Casey, I viewed an 'open' video that I appreciated the researcher approach, but could not resist trying to peak interest in adding melatonin from mitochondria, and D3 plus the other active forms to the list of research questions considered by this lab. I hope my comments to him can help spread the importance of your work into wider influence. Let me know if I am being premature, or inappropriate with this kind of communication with others? ua-cam.com/video/FfewbNsHPt0/v-deo.htmlsi=I-QGigDhJPZqoBG8 Jarred Younger Neuroinflammation, Pain, and Fatigue Lab at UAB comments to his site: Thank you for this 'open' approach! IMHO, searching across specialties and broadening 'peer review' exposure seems prerequisite for best scientific method toward more fruitful outcomes. I have recently come to understand need for approaches considering quantum biology knowledge as a bedrock to inform QA/QC for such important effort. Lab subjects are all evolved by having adapted over untold thousands of years to thrive outdoors. The complexities involved in their physiologies, we are only 'scratching the surface of'. The energy carried in the orchestra of daylight breadth of wavelengths sustains physiology complexity. Lab environments, lit by LEDs and fluorescent light, w/o benevolent modulation of 'what was left outdoors' really DOES need to be accounted for. Lab animal physiology (especially human), is essentially and thoroughly tied to the physics effects of the specific light reaching it. Shinning toxic isolated narrow bands of wavelengths biases the resultant outcomes of testing. Best wishes for your work, onward and upward into the light. On the list under hormones, I would highlight 'mitochondrial melatonin' as well as pineal melatonin. Also, Vitamin D3 hormone plus its other active forms produced in daylight. Dr, casey Peveler on YT has summaries of research on these as presentation videos.
Keep at it Casey - more than anyone else I am aware of, I think you are both genuine and knowledgable. I feel like the main obstruction to progress is 'big pharma'. The biochemistry might be complex, but 'eating real food' is not. Here for the journey forward ... Go for it !
Thank you for your support and encouragement. It really helps. Any industry that loses money on less sick people and profits off more sick people is the problem.
@@raykinney9907 What took decades to occur cannot be solved overnight - first thing to do is what one should have done all those previous years. But with some differences - for example, where a variety of fruit such as berries might once have been a great choice, now one might choose extracts instead to avoid the sugar content. That aside, imo the prevention and management of C is more or less the same. Imo, one should zoom out and fix the bigger picture rather than focus on the specific ailment, first of all.
I'm not to this one yet, but loving these video's, great depth into the science behind Jack Kruse et all. Just a suggestion, can you sort the playlist in the order we should watch them? It's currently latest first (except this one which is last) which makes it more difficult than it should be to watch these in an order that makes sense.
Thank you for your kindness. Lets just be honest, this is dense science with uses other areas of dense science to understand all of it. Its hard to know where to start because even starting in one direction, requires background information you may or not have. I think the best is to watch them from the very first video in the cancer as a metabolic disease series. I go from what is cancer, all the way through conventional views and unconventional views. Break down normal and cancer metabolism. Then when we get here, talking about Vitamin D or melatonins affect on glycolysis, HIF1a, glutamine, you already understand to some degree why that is so critical. Hope that helps some...and thank you for your support!
The dose, timing, and scheduling would be a conversation between you and your doctor. I have seen doses from 30mg to 180mg nightly, as well as 120mg 4x per day upwards of gram quantities. The recommendations are vast and need to be tailored for your specific issue. I hope this at least gets you started.
Hey doc! my mother is eating apricot seeds from past 20 days , she experiences headache after eating them . she is having phyllodes breast tumor for which she is consuming apricot seeds.is this serious? Should she stop eating them. She consumes 4 seeds daily
I have obviously heard of this alternative strategy. I even to some degree understand the proposed mechanism it is supposed to employ. I cannot say that I have heard a lot of success stories from using them and they may be dangerous. I think this highlights a key point that you need to at least have some guidance from a like minded local integrative healthcare provider.
FYI Thank you Casey. I have begun maximizing my sun exposure these last few days and in the short time that I have, my pain and inflammation has reduced substantially.
Brilliant video ! Wow Melatonin does so so much ! I make sure to always wear blue blockers at night inside and outside . The issue I have is a huge Power Line next to my house , how bad are they? Any way to protect against them?
Thank you and I am glad you enjoyed the video! Melatonin is a miracle hormone! When it comes to EMF you have to test. Test the electric, magnetic, and radio frequency fields. Also need to test dirty electricity and body voltage. Hire an EMF specialist or a building biologist. Hard to know but that might be hard to mitigate. In my experience radio frequency/microwaves are the easiest to shield.
Allow me to approach dosing from a different angle-because I don't have a doctor to converse with. If I were to start taking 30mg of melatonin every night, how long before, I might notice an improvement in my energy levels and /or other effects of inflamation?
Thank you for your question. It would be impossible to say the energy component because I do not know what’s wrong with you. That should be investigated it sounds like. The inflammatory question would also be somewhat difficult. Has the cause or causes of inflammation been investigated and addressed? The hormone would have immediate effect once in your system, but you would need to track your symptoms and inflammatory markers to look for both subjective and objective evidence.
What would be the optimal duration of a morning walk to boost the health of mitochondria? I mean, one could walk say, 4h to get 100% of benefit. But maybe 2h is enough to reap 90%, making the first 2 hours optimal. Any idea?
That is a great question. Walking is a powerful overall health strategy. Generally recommendations would be get more than 8,000 steps per day. That takes roughly 80 minutes to accomplish. If you look at that graph you get rapid spikes in as little as 20 min. So a long walk or maybe 3-5 shorter walks could also likely work.
If you live in a high latitude country and sunset is at 4pm. Would it be best to put red lights on in the evening? I was thinking what if I have UV full spectrum bulbs on till 6pm, and then use red lights till 10pm and blue blocking glasses that would be okay, hmmmm. It's tricky
Are you generally well or are you dealing with disease of any kind? Context would be king here. In general, nothing less than about 550nm after sunset.
So what is the takeaway, especially if one desires metabolic therapy to inhibit cancer? Get more sun? Can we increase melatonin in healthy cells and reduce it in cancerous cells?
We want melatonin in every cell of your body. ESPECIALLY cancer cells where it inhibits Warburg metabolism. Sunlight and darkness are your allies. If you have cancer, can discuss exogenous supplemental melatonin with your doctor.
@@DrCaseyPeavler My doctor (ND) did prescribe me a melatonin supplement which I take at night. I am thinking that I don't want to inhibit ROS in cancer cells.. but if it reduces fermentation and they can't respire, then they die that way
What I showed I believe in the prior video, is that in cancer cells, melatonin INCREASES ROS. So no need to worry about that. In normal cells, decreases ROS and oxidative damage. Miraculous.
Would be a discussion between the patient and their healthcare provider. I have seen doses of 30mg nightly to 180mg nightly to 120mg 4x/d talked about by integrating doctors when dealing with patients with cancer.
I would have to recommend you talk to a healthcare provider about specifics. That being said, I have seen anywhere from 30mg nightly to 180mg nightly to 120mg 4x/d used. But these exact recommendations should be between you and your doctor. Also, no matter if you are supplementing or not, you need to be getting max solar and NIR exposure to make your own as well. The supplemental would be just that, a supplement to maximum endogenous production. That also includes max attention to circadian biology and adequate darkness in your evening and night.
For some reason my anxiety is much better now from only 3 days of Sun I wasn’t able to get sunlight because of monsoons in India. Does sunlight of vitamin D has a relationship with this mood behaviour?
Vitamin D possibly as it does have an effect on glutamate which is a stimulator’s neurotransmitter, but dopamine, serotonin, beta-endorphin, met-enkephalin definitely do which are all modulated by sunlight. Plus it’s a more balanced light of red/blue so it takes your body out of sympathetic overdrive (fight or flight).
12:51 supplementing with melatonin has definitely helped me feel refreshed and less “inflamed” and aching joints reduced - making me think it was reducing or somehow interacting with LPS (endotoxins) - remember n=1 🙂
Now we have proof! Before I read these papers I didn’t realize melatonin was an anti-inflammatory…but after getting into the literature, it seems to be extremely powerful on that front. No wonder you noticed what you did.
I've read mouse studies (Pub Med?) using high dose melatonin (10mg/kg) in drinking water of aged animals for (30 days?). The results showed rejuvenated thymus and improved spleen weight.
Does not surprise me. Melatonin is a master regeneration hormone. I think because it is over the counter and so ubiquitous on store shelves and cheap its not useful or powerful. But we would be wrong...
So, what mechanisms regulate the 'regulator'? Too much of a good thing could ever be problematic? More NIR, more UV, yielding more mitochondrial melatonin, what's the limiting high end feedback loop(s)? I assume you can't be outdoors in daylight too much. Could there be too much curtailment of ROS, to limit signaling function? And, have our lifestyles of starvation of NIR, brought so much inflammation as to increase ROS so much that the glutathione is chronically depleted too much, so it is such 'a breath of fresh air' to mitochondrial function every time we DO manage to get 'the next little hit' of daylight, or incandescent light? So much work to do! So many sunglasses to throw away? Don't even want to give them to anyone else. Bless us all! and thank you Casey!
Best chance, imo, comes from choosing life - being at peace, being positive, helping others, enjoying nature and the sun and moon and grass and mountains and sea. Letting go of the past. Eating fresh food. Loving life.
Wow! So lifestyles indoors, working and sleeping w/o NIR (and almost no daylight REGULARLY) prevent adequate and timely resupply of half-life modulated melatonin very quickly and pervasively.... leaving a lot of unnecessary inflammation! So, I've built my house (my cocoon) with low e-glass, have LED light bulbs (which now know I need to replace back to hard-to- get incandescent bulbs where possible), or run outside very frequently for twenty minute 'hits' of life-giving daylight?!! So, now with all this puzzling activity back and forth, my family, friend, relatives, and potential friends will laugh and really think I've 'gone over the EDGE'! And, if I were to try to point out to them just WHY I had to run around like this to stay healthy, and that THEY were getting chronic diseases more because THEY were not also running around like a headless chicken out into the dreary winter rain forest every couple of hours, I will continue to be 'their conspiracy theorist'' whackadoodle' entertainment? It is going to be a LOT of work explaining some sense of this complexity, to get any appreciable credibility back. And, if I use too many big words, it will be destined to fail. What a 'pickle' we are all in when we 'get' the enormity of the implications, with the NEED for lifestyle changes quickly. Ha, Ha, going to be interesting living indoors, but trying to really make it 'the outdoors'. Powerful information!
We can always fall back on party incandescence, reptile bulbs etc. And because Scott Zimmerman is a genius, his bulbs are in compliance with regulations but have both natural spectrum and IR built in. When I move I will have my house filled with bulbs from Scott and EMR-tek both of which I have tested and like alot. But more importantly having sliding glass doors and windows open during day or just sitting out in the shade as much as possible. You really do have to re-think everything you likely have in place now.
Can you look in to and do a video on cell suppression theory of cancer posited by Mark Lintern. I don't think cancer is caused by DNA mutations and whilst it can be described as a metabolic disease, this isn't appearing to be what it actually is... To me it appears to be a microorganism based disease at its root. Not to be dismissed as just another player on the field of the tumour microenvironment as it has been so far by oncology and even integrative practitioners. No, this is literally what it actually is. Metabolic approaches think they are treating the cancer cell, but all along it could just be treating the microorganisms both intracellular and extracellular of the tumour cells. The main scapegoat for the observable warburg effect could very well be fungi, supported by a host of other microorganisms. The warburg effect is also an infection response by cells under Dr Naviaux's danger response model. This is what cell suppression posits. The cancer cell is merely the vehicle, whilst the fungal pathogen is its driver. Treatments fail to work long term because they are focused on bashing up the vehicle. But the driver just gets out and jumps in a new (and improved/resistant) one. Yet if we take out the driver, the vehicle runs off the road with it.
I have, and still, wonder about this ... Not sure, maybe it's just a tipping point of mitochondrial damage, but there could be microrganism hijacking involved - I'm open minded on this. As anyone should be. I have confidence in Casey to follow the evidence - and so will I - wherever it leads ...
I am picking up what you are laying down in a very clear as concise manor. I have heard of theories such as this. I have no problem learning about the author you mentioned. Getting through the material and learning about it. I don’t think I could realistically produce a video on it anytime soon just because it sounds like you have a better grasp than I do at this point. But I will check it out.
@@DrCaseyPeavler thank you, the theory was only released last year - it claims to coherently explain all the hanahan hallmarks of cancer, and the process of carcinogenesis in a sequentially explained fashion. I've struggled to take it down as I don't want to follow a path of false hope in treating my wife who is now on month 30 of NSCLC derived brain mets (Kras Adenocarcinoma). I think Mark Lintern may have overlooked the role of parasites, or underestimated their role as they are not too dissimilar to fungi. I'm following a protocol, which comprises a 10 day cycle of anti fungal drugs (fluconazole, itraconazole, Nystatin, ADP Oregano Oil), following by a 10 day cycle of anti parasitic drugs that i have seen scans show it is shrinking glioblastoma without conventional treatment, consistently now for 6 months (near unheard of - usually it just stops growing for a bit at best, or there is some conventional treatment involved, or it works for a couple months and quickly acquires resistance). The person reported their best improvement after following the first 10 day cycle of anti parasitics (ivermectin, tinidazole, praziquantel, pyrantel pamoate, doxycyline and artemisinin) Mark Lintern rightly suggests many anti parasitic drugs are inherently anti fungal, which is true in some cases but it doesn't explain why this anecdote felt more better after anti parasitics than anti fungals. I'm hoping you could put a critical eye across the theory, the author is very welcoming of this, and am happy to invite you to his facebook group, i'm well versed in the theory, by no means a cancer expert, just a somewhat smart dude trying to save his wife, thank you for listening
And, even the science labs are NIR and daylight starved? How to control for all of that hubris?!? And, the gyms the same? And how to control for that? Just go outside every couple of hours, to get some life-giving free therapy? How many drugs can we do without?
Its blatantly obvious the main issues that plagues humanity is lack of full spectrum natural light during the day (sunlight deficiency) and overexposure of artificial light particularly at night (darkness deficiency).
@@DrCaseyPeavler I also eat a LOT of eggs. I'm thinking that if they are well pastured so grass/bug/seeds etc. the chicken bodies have already done a lot to filter out possible contaminants, and probably are low deuterium content. Plus they are a pretty nutritious food that we are very evolutionarily adapted to thrive on. For mitochondrial benefit, the deuterium reduction potential might turn out to be big.
Can you believe how powerful melatonin is?
Indeed! The design of our bodies is truly awesome.
Absolutely amazing! Just wondering if your view(s) on exogenous supplementation might change the further you look into it 🙄🙊🙃
Supplemrnt?
Casey, I viewed an 'open' video that I appreciated the researcher approach, but could not resist trying to peak interest in adding melatonin from mitochondria, and D3 plus the other active forms to the list of research questions considered by this lab. I hope my comments to him can help spread the importance of your work into wider influence. Let me know if I am being premature, or inappropriate with this kind of communication with others?
ua-cam.com/video/FfewbNsHPt0/v-deo.htmlsi=I-QGigDhJPZqoBG8
Jarred Younger
Neuroinflammation, Pain, and Fatigue Lab at UAB
comments to his site:
Thank you for this 'open' approach! IMHO, searching across specialties and broadening 'peer review' exposure seems prerequisite for best scientific method toward more fruitful outcomes. I have recently come to understand need for approaches considering quantum biology knowledge as a bedrock to inform QA/QC for such important effort. Lab subjects are all evolved by having adapted over untold thousands of years to thrive outdoors. The complexities involved in their physiologies, we are only 'scratching the surface of'. The energy carried in the orchestra of daylight breadth of wavelengths sustains physiology complexity. Lab environments, lit by LEDs and fluorescent light, w/o benevolent modulation of 'what was left outdoors' really DOES need to be accounted for. Lab animal physiology (especially human), is essentially and thoroughly tied to the physics effects of the specific light reaching it. Shinning toxic isolated narrow bands of wavelengths biases the resultant outcomes of testing. Best wishes for your work, onward and upward into the light.
On the list under hormones, I would highlight 'mitochondrial melatonin' as well as pineal melatonin. Also, Vitamin D3 hormone plus its other active forms produced in daylight. Dr, casey Peveler on YT has summaries of research on these as presentation videos.
Absolutely, hence so many Black ppl coming up missing all the time.
Keep at it Casey - more than anyone else I am aware of, I think you are both genuine and knowledgable.
I feel like the main obstruction to progress is 'big pharma'.
The biochemistry might be complex, but 'eating real food' is not. Here for the journey forward ... Go for it !
Thank you for your support and encouragement. It really helps. Any industry that loses money on less sick people and profits off more sick people is the problem.
Yes, pieces of the puzzle!
@@BeijingBuzzz-China-Travel
Wonderful encouraging statement!
❤️❤️
@@raykinney9907 What took decades to occur cannot be solved overnight - first thing to do is what one should have done all those previous years. But with some differences - for example, where a variety of fruit such as berries might once have been a great choice, now one might choose extracts instead to avoid the sugar content. That aside, imo the prevention and management of C is more or less the same. Imo, one should zoom out and fix the bigger picture rather than focus on the specific ailment, first of all.
@@BeijingBuzzz-China-Travel Yup!
I just rematch the D3, and melatonin videos. They just blew me away again! Wow. How many oncologists have not read these papers? I wonder...
Don’t get me started Ray lol…the next 2 melatonin videos will about cancer prevention and treatment. Buckle up.
I'm not to this one yet, but loving these video's, great depth into the science behind Jack Kruse et all. Just a suggestion, can you sort the playlist in the order we should watch them? It's currently latest first (except this one which is last) which makes it more difficult than it should be to watch these in an order that makes sense.
Thank you for your kindness. Lets just be honest, this is dense science with uses other areas of dense science to understand all of it. Its hard to know where to start because even starting in one direction, requires background information you may or not have. I think the best is to watch them from the very first video in the cancer as a metabolic disease series. I go from what is cancer, all the way through conventional views and unconventional views. Break down normal and cancer metabolism. Then when we get here, talking about Vitamin D or melatonins affect on glycolysis, HIF1a, glutamine, you already understand to some degree why that is so critical.
Hope that helps some...and thank you for your support!
thank you very much for making your videos. it is appreciated.
You are very welcome!
Dr Casey. What dose would we take for effective mitigation of prostate cancer?. I have read it inhibits signaling pathways
The dose, timing, and scheduling would be a conversation between you and your doctor. I have seen doses from 30mg to 180mg nightly, as well as 120mg 4x per day upwards of gram quantities. The recommendations are vast and need to be tailored for your specific issue. I hope this at least gets you started.
Hey doc! my mother is eating apricot seeds from past 20 days , she experiences headache after eating them . she is having phyllodes breast tumor for which she is consuming apricot seeds.is this serious? Should she stop eating them. She consumes 4 seeds daily
I have obviously heard of this alternative strategy. I even to some degree understand the proposed mechanism it is supposed to employ. I cannot say that I have heard a lot of success stories from using them and they may be dangerous. I think this highlights a key point that you need to at least have some guidance from a like minded local integrative healthcare provider.
FYI Thank you Casey. I have begun maximizing my sun exposure these last few days and in the short time that I have, my pain and inflammation has reduced substantially.
Endorphins at least!
Amen! 🙏 AND it’s free…
Brilliant video ! Wow Melatonin does so so much !
I make sure to always wear blue blockers at night inside and outside .
The issue I have is a huge Power Line next to my house , how bad are they? Any way to protect against them?
Thank you and I am glad you enjoyed the video! Melatonin is a miracle hormone!
When it comes to EMF you have to test. Test the electric, magnetic, and radio frequency fields. Also need to test dirty electricity and body voltage. Hire an EMF specialist or a building biologist. Hard to know but that might be hard to mitigate. In my experience radio frequency/microwaves are the easiest to shield.
Allow me to approach dosing from a different angle-because I don't have a doctor to converse with. If I were to start taking 30mg of melatonin every night, how long before, I might notice an improvement in my energy levels and /or other effects of inflamation?
Thank you for your question. It would be impossible to say the energy component because I do not know what’s wrong with you. That should be investigated it sounds like.
The inflammatory question would also be somewhat difficult. Has the cause or causes of inflammation been investigated and addressed? The hormone would have immediate effect once in your system, but you would need to track your symptoms and inflammatory markers to look for both subjective and objective evidence.
Great info as always, wondering if you’ve looked into how lack iodine might affect the mitochondria?
I have yes. I have tried to look at every known nutrient that directly impacts mitochondria. I will be sharing those in future videos!
tx for the video! Did u hear about Normotim? It seems to have a similar effect to melatonin. WYD think about it?
You are very welcome. No I have not heard about it, but I can look into it though!
What would be the optimal duration of a morning walk to boost the health of mitochondria? I mean, one could walk say, 4h to get 100% of benefit. But maybe 2h is enough to reap 90%, making the first 2 hours optimal. Any idea?
That is a great question. Walking is a powerful overall health strategy. Generally recommendations would be get more than 8,000 steps per day. That takes roughly 80 minutes to accomplish. If you look at that graph you get rapid spikes in as little as 20 min. So a long walk or maybe 3-5 shorter walks could also likely work.
Which graph? @@DrCaseyPeavler
Should be in this video when talking about NIR:
ua-cam.com/video/NnPikAeMUXI/v-deo.html
If you live in a high latitude country and sunset is at 4pm.
Would it be best to put red lights on in the evening?
I was thinking what if I have UV full spectrum bulbs on till 6pm, and then use red lights till 10pm and blue blocking glasses that would be okay, hmmmm.
It's tricky
Are you generally well or are you dealing with disease of any kind? Context would be king here. In general, nothing less than about 550nm after sunset.
So what is the takeaway, especially if one desires metabolic therapy to inhibit cancer? Get more sun? Can we increase melatonin in healthy cells and reduce it in cancerous cells?
We want melatonin in every cell of your body. ESPECIALLY cancer cells where it inhibits Warburg metabolism. Sunlight and darkness are your allies. If you have cancer, can discuss exogenous supplemental melatonin with your doctor.
@@DrCaseyPeavler My doctor (ND) did prescribe me a melatonin supplement which I take at night. I am thinking that I don't want to inhibit ROS in cancer cells.. but if it reduces fermentation and they can't respire, then they die that way
What I showed I believe in the prior video, is that in cancer cells, melatonin INCREASES ROS. So no need to worry about that. In normal cells, decreases ROS and oxidative damage. Miraculous.
What sort of dosages would be used in these contexts?
Context is king. Are you healthy, with mild disease or have severe disease like cancer?
@@DrCaseyPeavler asking for someone who has cancer
Would be a discussion between the patient and their healthcare provider. I have seen doses of 30mg nightly to 180mg nightly to 120mg 4x/d talked about by integrating doctors when dealing with patients with cancer.
What would be a good dosage for someone with cancer
I would have to recommend you talk to a healthcare provider about specifics. That being said, I have seen anywhere from 30mg nightly to 180mg nightly to 120mg 4x/d used. But these exact recommendations should be between you and your doctor. Also, no matter if you are supplementing or not, you need to be getting max solar and NIR exposure to make your own as well. The supplemental would be just that, a supplement to maximum endogenous production. That also includes max attention to circadian biology and adequate darkness in your evening and night.
@@DrCaseyPeavler thank you
You are very welcome!
For some reason my anxiety is much better now from only 3 days of Sun I wasn’t able to get sunlight because of monsoons in India.
Does sunlight of vitamin D has a relationship with this mood behaviour?
Vitamin D possibly as it does have an effect on glutamate which is a stimulator’s neurotransmitter, but dopamine, serotonin, beta-endorphin, met-enkephalin definitely do which are all modulated by sunlight. Plus it’s a more balanced light of red/blue so it takes your body out of sympathetic overdrive (fight or flight).
You didn't give dosage for 60 plus?
I don’t recommend supplements except for extreme cases to be honest. You make your own in nearly unlimited quantities under the right conditions.
12:51 supplementing with melatonin has definitely helped me feel refreshed and less “inflamed” and aching joints reduced - making me think it was reducing or somehow interacting with LPS (endotoxins) - remember n=1 🙂
Now we have proof! Before I read these papers I didn’t realize melatonin was an anti-inflammatory…but after getting into the literature, it seems to be extremely powerful on that front. No wonder you noticed what you did.
@@DrCaseyPeavler wish more Dr’s were as open minded as you! Appreciate the work and the videos as always! 💪 🙏
@@DrCaseyPeavler Yes, one surprise after another.
You are very welcome! I really have enjoyed making them, somewhat enjoy editing them lol as it is very tedious. Thank you for the support!
@@DrCaseyPeavler lol yeh I’m sure the editing can become tedious somewhat! Nevertheless, your work and you are very much appreciated 🙏 💪 💚
I can’t help staring at your lips 😂
Lol not sure what to make of that. I am glad you liked the video.
I've read mouse studies (Pub Med?) using high dose melatonin (10mg/kg) in drinking water of aged animals for (30 days?).
The results showed rejuvenated thymus and improved spleen weight.
Does not surprise me. Melatonin is a master regeneration hormone. I think because it is over the counter and so ubiquitous on store shelves and cheap its not useful or powerful. But we would be wrong...
This is a running sentence
Yah, needs to run fast because time is running out! Good thing tech can slow the speed down as needed for playback.
@@raykinney9907 sounds like a Ai
I’ve always admired Lt. Commander Data on Star Trek TNG…but no not AI
So, what mechanisms regulate the 'regulator'? Too much of a good thing could ever be problematic? More NIR, more UV, yielding more mitochondrial melatonin, what's the limiting high end feedback loop(s)? I assume you can't be outdoors in daylight too much. Could there be too much curtailment of ROS, to limit signaling function?
And, have our lifestyles of starvation of NIR, brought so much inflammation as to increase ROS so much that the glutathione is chronically depleted too much, so it is such 'a breath of fresh air' to mitochondrial function every time we DO manage to get 'the next little hit' of daylight, or incandescent light? So much work to do! So many sunglasses to throw away? Don't even want to give them to anyone else. Bless us all! and thank you Casey!
There IS almost always shade outside to move out of too much sun!
As Uncle Jack says "Why discuss too much when 99% of people get too little?"
Yup, and there is a lot of benefit to shade. Reflexion of UV and IR both!
@@DrCaseyPeavler Hmmm, I must be around 62%.
Better than being completely oblivious to the problem and wondering why their health is deteriorating....knowledge is power...
? Yes or no
No not AI…I wish, would save me a lot of time and energy ha
Best chance, imo, comes from choosing life - being at peace, being positive, helping others, enjoying nature and the sun and moon and grass and mountains and sea. Letting go of the past. Eating fresh food. Loving life.
Amen 🙏 to that.
Wow! So lifestyles indoors, working and sleeping w/o NIR (and almost no daylight REGULARLY) prevent adequate and timely resupply of half-life modulated melatonin very quickly and pervasively.... leaving a lot of unnecessary inflammation!
So, I've built my house (my cocoon) with low e-glass, have LED light bulbs (which now know I need to replace back to hard-to- get incandescent bulbs where possible), or run outside very frequently for twenty minute 'hits' of life-giving daylight?!! So, now with all this puzzling activity back and forth, my family, friend, relatives, and potential friends will laugh and really think I've 'gone over the EDGE'! And, if I were to try to point out to them just WHY I had to run around like this to stay healthy, and that THEY were getting chronic diseases more because THEY were not also running around like a headless chicken out into the dreary winter rain forest every couple of hours, I will continue to be 'their conspiracy theorist'' whackadoodle' entertainment?
It is going to be a LOT of work explaining some sense of this complexity, to get any appreciable credibility back. And, if I use too many big words, it will be destined to fail. What a 'pickle' we are all in when we 'get' the enormity of the implications, with the NEED for lifestyle changes quickly. Ha, Ha, going to be interesting living indoors, but trying to really make it 'the outdoors'. Powerful information!
Whackadoodle!
Hilarious 😂😂
Incandescent lighting is harder to find, but not impossible!
Life is easier without neighbors. Fuggem..
@@gmw3083 Relatives?
We can always fall back on party incandescence, reptile bulbs etc. And because Scott Zimmerman is a genius, his bulbs are in compliance with regulations but have both natural spectrum and IR built in. When I move I will have my house filled with bulbs from Scott and EMR-tek both of which I have tested and like alot. But more importantly having sliding glass doors and windows open during day or just sitting out in the shade as much as possible. You really do have to re-think everything you likely have in place now.
@DrCaseyPeavler
Dr. P, thanks for sharing your very helpful Knowledge!
Can you look in to and do a video on cell
suppression theory of cancer posited by Mark Lintern.
I don't think cancer is caused by DNA mutations and whilst it can be described as a metabolic disease, this isn't appearing to be what it actually is...
To me it appears to be a microorganism based disease at its root. Not to be dismissed as just another player on the field of the tumour microenvironment as it has been so far by oncology and even integrative practitioners. No, this is literally what it actually is. Metabolic approaches think they are treating the cancer cell, but all along it could just be treating the microorganisms both intracellular and extracellular of the tumour cells. The main scapegoat for the observable warburg effect could very well be fungi, supported by a host of other microorganisms. The warburg effect is also an infection response by cells under Dr Naviaux's danger response model. This is what cell suppression posits. The cancer cell is merely the vehicle, whilst the fungal pathogen is its driver. Treatments fail to work long term because they are focused on bashing up the vehicle. But the driver just gets out and jumps in a new (and improved/resistant) one. Yet if we take out the driver, the vehicle runs off the road with it.
I have, and still, wonder about this ... Not sure, maybe it's just a tipping point of mitochondrial damage, but there could be microrganism hijacking involved - I'm open minded on this. As anyone should be. I have confidence in Casey to follow the evidence - and so will I - wherever it leads ...
I am picking up what you are laying down in a very clear as concise manor. I have heard of theories such as this. I have no problem learning about the author you mentioned. Getting through the material and learning about it. I don’t think I could realistically produce a video on it anytime soon just because it sounds like you have a better grasp than I do at this point. But I will check it out.
@@DrCaseyPeavler Definately worth keeping an open mind about this. Imo, it's plausible.
Mind is open, no need to worry about that
@@DrCaseyPeavler thank you, the theory was only released last year - it claims to coherently explain all the hanahan hallmarks of cancer, and the process of carcinogenesis in a sequentially explained fashion. I've struggled to take it down as I don't want to follow a path of false hope in treating my wife who is now on month 30 of NSCLC derived brain mets (Kras Adenocarcinoma). I think Mark Lintern may have overlooked the role of parasites, or underestimated their role as they are not too dissimilar to fungi. I'm following a protocol, which comprises a 10 day cycle of anti fungal drugs (fluconazole, itraconazole, Nystatin, ADP Oregano Oil), following by a 10 day cycle of anti parasitic drugs that i have seen scans show it is shrinking glioblastoma without conventional treatment, consistently now for 6 months (near unheard of - usually it just stops growing for a bit at best, or there is some conventional treatment involved, or it works for a couple months and quickly acquires resistance). The person reported their best improvement after following the first 10 day cycle of anti parasitics (ivermectin, tinidazole, praziquantel, pyrantel pamoate, doxycyline and artemisinin) Mark Lintern rightly suggests many anti parasitic drugs are inherently anti fungal, which is true in some cases but it doesn't explain why this anecdote felt more better after anti parasitics than anti fungals.
I'm hoping you could put a critical eye across the theory, the author is very welcoming of this, and am happy to invite you to his facebook group, i'm well versed in the theory, by no means a cancer expert, just a somewhat smart dude trying to save his wife, thank you for listening
Vitamind lamp 😜
They work!
No substitute for the sun, that being said.
And, even the science labs are NIR and daylight starved? How to control for all of that hubris?!?
And, the gyms the same? And how to control for that? Just go outside every couple of hours, to get some life-giving free therapy? How many drugs can we do without?
Its blatantly obvious the main issues that plagues humanity is lack of full spectrum natural light during the day (sunlight deficiency) and overexposure of artificial light particularly at night (darkness deficiency).
Hospitals!?!!!
Don’t get me started…
@@DrCaseyPeavler Boom!
Haha classic Uncle Jack
Eat LOTS OF EGGS
I eat a lot of eggs myself, but can you please help me understand what you mean?
@@DrCaseyPeavler I also eat a LOT of eggs. I'm thinking that if they are well pastured so grass/bug/seeds etc. the chicken bodies have already done a lot to filter out possible contaminants, and probably are low deuterium content. Plus they are a pretty nutritious food that we are very evolutionarily adapted to thrive on. For mitochondrial benefit, the deuterium reduction potential might turn out to be big.
Thanks Ray! Definitely higher fat foods have lower deuterium. That is true.