What Science ACTUALLY Says About Glucosamine & Chondroitin

Поділитися
Вставка
  • Опубліковано 25 січ 2023
  • I review Glucosamine Sulfate and Chondroitin for Joint Pain & Arthritis.
    pubmed.ncbi.nlm.nih.gov/35924...
    pubmed.ncbi.nlm.nih.gov/35024...
    bjsm.bmj.com/content/52/3/167...
    ► Things my patients have found helpful:
    Please note that I get a lot of requests and questions about what equipment is ‘best’ for treating a variety of conditions. The following is not meant to be an exhaustive or definitive list. Please use it as a starting point. If you have questions, please discuss with your healthcare provider. With that said, I have tried a number of the products below, but not all. I have included some based on positive feedback from many of my patients. As an Amazon Associate, Dr Peng earns from qualifying purchases. If you purchase any product using the below affiliate links, you are helping Dr Peng maintain this channel.
    Supplements
    The following are Thorne supplements which are NSF certified. NSF independently assesses products without being affiliated with the companies that produce them. Not only do they certify that what’s on the label is in the bottle, they also do toxicology review to certify product formulation and contaminant review to ensure the product contains no undeclared ingredients or unacceptable levels of contaminants.
    Boswellia Extract: amzn.to/3L00rYn
    Turmeric & Curcumin: ​​amzn.to/47NacD9
    Glucosamine & Chondroitin: amzn.to/44AVoow
    Creatine Monohydrate: amzn.to/45JW9wq
    Omega 3 and 6: amzn.to/45LTBh7
    Vitamin D 5000: amzn.to/47T8MHs
    Vitamin B complex: amzn.to/3L0Bdcm
    Magnesium: amzn.to/3snHuZc
    Soft Tissue & Rehab
    Theragun: amzn.to/4363zJG
    Massage ball: amzn.to/40BUC9f
    Foam roller: amzn.to/4324E5c
    Stretching strap: amzn.to/3U9a2iQ
    TENS unit: amzn.to/3mcCqnI
    Heating pad: amzn.to/40VidSc
    Resistance bands: amzn.to/3nFyb4C
    Braces & Supports
    Hinged knee brace: amzn.to/3U6oyrH
    Neoprene knee sleeve: amzn.to/3Zzhsgt
    Volar wrist brace: amzn.to/3KawW55
    Thumb spica brace: amzn.to/3nHj9vl
    Ankle lace up brace: amzn.to/3m6iR0u
    Tennis/Golfer’s elbow brace: amzn.to/3ZEGgE1
    Superfeet orthotic inserts: amzn.to/436tRf5
    Recommended Textbooks & Resources
    The Trigger Point Manual: amzn.to/4340cTt
    Trigger Point Wall Charts: amzn.to/3zrinVR
    ► Be Active. Live Healthy. Subscribe for more free videos like this: / @jeffreypengmd
    ► ABOUT ME
    Jeffrey Peng MD is a nonoperative orthopedist and sports medicine specialist. He created a UA-cam channel and blog to translate cutting edge medical knowledge and clinical research to benefit all those looking to live an active and healthy lifestyle. He focuses on maximizing non-surgical treatments for sports injuries and orthopedic conditions. He specializes in using orthobiologics and ultrasound guided minimally invasive techniques to treat osteoarthritis, tendinopathies, and musculoskeletal disorders.
    Dr. Peng is board certified in sports medicine and family medicine. He completed residency with the Stanford family medicine residency program and completed his sports medicine training with the Stanford primary care sports medicine fellowship in San Jose. He is an active faculty member for both programs and is excited about training the next generation of physicians.
    Dr. Peng’s sports medicine clinic is located in Campbell, California.
    Twitter: @JeffreyPengMD; / jeffreypengmd
    Website: www.jeffreypengmd.com/
    ► Disclaimer
    My content reflects my own opinion and does not represent the views or opinions of my employers or hospital systems I am affiliated with. They are meant for educational purposes only. They do not substitute for the medical advice of a physician. Always seek the advice of your physician with any questions you may have regarding your health.

КОМЕНТАРІ • 513

  • @garryjistel280
    @garryjistel280 7 місяців тому +259

    I have been taking glucosamine and condroitin for 40 years. It has kept me on my feet and avoid knee replacement. I am not going to stop it now. I was diagnosed with osteoarthritis in my mid 20's. I am now 68.

    • @tamilkalakkalkitchen623
      @tamilkalakkalkitchen623 6 місяців тому +3

      Is it true ?? Are you able to manage this situation for 40 years...

    • @phlotographer
      @phlotographer 6 місяців тому +10

      I have been using 1500 MG Glucosamine Sulfate from Costco for about half the time of your usage. It was recommended by a friend and I was told to use it for at least 2 weeks. Even prior to that the severe pain I had with my R achiles tendon was eliminated. However, when stopping usage, the pain immediately returned and so I have never stopped using the product and likely never will but I might do another test to see if the issue has totally disappeared over the years.

    • @tresahines9862
      @tresahines9862 6 місяців тому +8

      Wow thank you for that information, I don't want surgery

    • @leisurely6711
      @leisurely6711 4 місяці тому +2

      Have you gotten recent mri it ct scans? I wonder if there was any improvement

    • @HepCatJack
      @HepCatJack 4 місяці тому +1

      Some supplements also include Elk Velvet Antler (Cervus Elaphus Canadensis) and Devil's claw. Others have white willow bark, Boswellia serrata extract, Boswellic acid, Lumanite, Selenium, Maganese, Pantothenic acid and collagen.

  • @artwise1415
    @artwise1415 3 місяці тому +69

    I'm 73 years old. I don't have arthritis. I run. I'm physically active. I do take Glucosamine and chondroitin. My study is my aging body. When I don't take it for a month or two my knees and hips hurt and keep me from running and even from long walks. When I get back on the glucosamine and chondroitin, after a few weeks the pain diminishes to no pain at all. I can sprint, top speed, the joy of flying on my feet. I feel good in my body. It feels great to feel good. That's my personal research. Onward.

    • @richardf911
      @richardf911 2 місяці тому +2

      I've heard similar stories from a number of runners.
      Glucosamine works. Chondroitin is unnecessary.

    • @heleneikerenkotter2950
      @heleneikerenkotter2950 Місяць тому +5

      I would never take this supplement as a solo. They work better in combination. The better supplements come in combination and made with Glucosamine sulfate and Chondroitin sulfate and not Glucosamine and Chondroitin hydrochloride . These are not drugs and represent the vital structure of joint tissue itself. It also promotes resiliency of other flexible tissue such as skin , arteries ,veins and heart valves. This is information found on the container of my supplement and the maker does not mess with supplements that are useless. He does years of studies before he makes the product. My husband and I both take and notice a difference when we stop. If you are allergic to the shells of shellfish ( shrimp, crab and crawfish ) do not take. Look at most studies that discourage supplements and encourage OTC or steroid injection with jaundiced eye. You have to take this supplement for a period of time to notice a difference. This is not a quick fix. This is not instant pain relief and temporary . It takes time to ruin joints and it takes time for them to heal and repair.

    • @lynamor2959
      @lynamor2959 21 день тому

      Amen! 🙌💯💪

    • @a.scotth.9955
      @a.scotth.9955 7 днів тому

      My mother took it and eventually was pain free. I have arthritis in my thumb joint that joins my rest in one hand and in the middle of my hand to mt wtist in the other hand. I have arthritic damaged several fingers. Wonder if it would work for these locations. Don't see why not.

    • @sailingaeolus
      @sailingaeolus 5 днів тому

      Same for me but I'm mid 50s.

  • @phillipoleary2532
    @phillipoleary2532 3 місяці тому +32

    Glucosamine alone worked for me. At age fifty was told both knees needed replacement and I had severe pain. Glucosamine was recommended and now at age eighty nearing eighty one am still running upstairs. No pain, no grating, no locking for thirty years. Only addition was MSM at age seventy.

    • @rit20095
      @rit20095 2 місяці тому +2

      Great to hear that. I have been diagnosed with osteoarthritis of knee

    • @barkpeeler2000
      @barkpeeler2000 Місяць тому +1

      GC always worked like a charm for me. I'm older now and thinking about my knees as well so I just started on it again. Glad I came across your comment because no one is taking my natural knees from me thank you😅

  • @digital.mente.
    @digital.mente. Рік тому +351

    My own totally non scientific study with my own knees is that the supplement I take with glucosamine, chondroitin, collagen, msm, hyaluronic acid and a few vitamins means no pain in my knees. When I don't take it for a couple of days the pain comes back. You have to try different brands to see which works for you.

    • @JeffreyPengMD
      @JeffreyPengMD  Рік тому +25

      Thanks for sharing your experiences!

    • @scotchbarrel4429
      @scotchbarrel4429 Рік тому +8

      I just checked my glucosamine supplement, and bloody hell, there's no chondroitin in it 😂
      Great vid, had to change the filter to recent to pickup this new update, otherwise first results are vids from 2 - 6yrs ago, and all consensus on the skeptical side, which didn't feel to good, considering I'm taking this stuff, but my man has reassured me that I'm on the right track, just gotta find one that includes chondroitin.

    • @malihahaque3710
      @malihahaque3710 Рік тому +6

      Any side effects ?

    • @digital.mente.
      @digital.mente. Рік тому +9

      @@malihahaque3710 For me none that I have noticed.

    • @holycrapfreakinsweet
      @holycrapfreakinsweet Рік тому +7

      is there any way for us to eventually overcome the dependency with supplements? like sure, I'd want to take them on for a certain amount of time, but not ALL OF THE TIME. that to me is just not helping.

  • @islandbirdw
    @islandbirdw 3 місяці тому +10

    Your presentation was clear concise and easy to understand. As a wellness nurse I firmly believe knowledge is the key to helping people engage in pursuing healthy sustainable habits over a lifetime. People generally will be willing to make positive lifestyle changes if they can see benefits early in the course of any potential illness.

  • @martinpolach1330
    @martinpolach1330 Рік тому +12

    I will be 77 this summer ..
    I still xc and down hill ski….I ride a mt bike ….I have been taking glucosamine and chondroitin for more than 20 yrs …
    I’m VERY fortunate that I don’t have joint issues ..!! Studies or no…but it works for me …

  • @somerset6646
    @somerset6646 8 місяців тому +52

    I was skeptical, but I recently started taking glucosamine, chondroitin, MSM, and it has helped my knee pain and overall aches. I take the triple strength.

    • @Pellican516
      @Pellican516 2 місяці тому

      What is the triple strength

    • @isaacelone3699
      @isaacelone3699 Місяць тому

      ​@@Pellican516 probably 3 times more than the usual dosage sold on the market?

  • @voxpopuli348
    @voxpopuli348 4 місяці тому +18

    I am 66. I started taking G & C in the 90s when I was still doing ballet. I kept taking it. I still do yoga, hiking, weight training, biking. I plant to keep taking it to stay off meds and nsaids. I also take turmuric and hyaloronic acid for my joints and ligaments.

  • @annpringle8219
    @annpringle8219 Рік тому +4

    All your videos are great! Also glucosamine works for me and my knee pain.

  • @BillyG869
    @BillyG869 3 місяці тому +15

    In 1993 my wife and got rear ended by a truck on the freeway. After that my neck was trashed, so painful it literally limited me to muscle relanta and pain pills. Months after doctors, orthopedic surgeons and eventually chiropractors. Then I started taking a very heavy does of glucosamine/chondroitin. It took a few months to take hold, but eventually I believe my cartilage became more functional and possibly repaired itself. That is a fact and it made me functional once again. I’m now 77 work hard and take little meds. If I were to sustain another damaged joint, I would immediately turn to this supplement once again. It takes a steady intake of a sizable dose, and it takes several months to recognize its effects. See for yourself…

  • @Southprong59
    @Southprong59 3 місяці тому +24

    I have a bad case of osteoarthritis in my knee and took Glucosamine & Chondroitin pills for approximately 30 years and it helped somewhat. Then I switched to a liquid Glucosamine & Chondroitin approximately 18 years ago and it made a big difference. I experimented a couple of times by stopping my intake of Glucosamine & Chondroitin for 3-4 days and my pain increased. Obviously, you body absorbs liquids more readily than tablet forms; if you use Glucosamine & Chondroitin, I highly recommend trying the liquid form.

    • @theresahenry4936
      @theresahenry4936 3 місяці тому

      😢

    • @Pellican516
      @Pellican516 2 місяці тому

      What brand?

    • @Southprong59
      @Southprong59 2 місяці тому

      @@Pellican516 Nature's Way Joint Movement Glucosamine, Extra Strength - each serving contains 2000mg Glucosamine, 1200 mg Condroitin, msm, and vitamin D3. I purchased mine online through Vitacost. I took 3-3.5 teaspoons every day. You may want to start out with a little heavier daily dose for the first week to get it into your system and back of to 3 full teaspoons a day. I also take psyllium husk every day and mixed the liquid Glucosamine and water with my powdered psyllium husk. It doesn't taste bad; you could take it by itself or mixed with water or juice.

    • @RobertBee-fs8hv
      @RobertBee-fs8hv 13 днів тому

      Never heard of liquid form

  • @67daltonknox
    @67daltonknox 4 місяці тому +15

    In my late 40s I had knee pain hiking and skiing. I even took up scuba so I would have a sport if my knees got worse. I also started G&C daily. It took a couple of years, but I was able to stop using neoprene compression on my knees. Now 76, my knees are fine and I'm still hiking and skiing, yes and taking G&C.

  • @tabathv1
    @tabathv1 22 дні тому +1

    I have been taking them since my thirty’s to avoid having problems as my mother suffered from arthritis. I’m nearly 60 and gave to say my joints are in good condition for my age

  • @edwinthomas618
    @edwinthomas618 23 дні тому +2

    It works for me as i had Hip Flexor pain. Thank God I found this miracle 😊

  • @MyNigellus
    @MyNigellus Рік тому +4

    Thank you very much for tackling this topic. Very useful for an average everyday user

  • @joecook8352
    @joecook8352 4 місяці тому +25

    In my early thirties my elbows and knees would get horribly stiff and painful, I saw a 60 minutes show about msm, glucosamine and chondroitin and there were several older people talking about there experience with it, this was in the late eighties. I started taking it and it helped tremendously. I’ve taken them ever since and I’m 64 now. It worked for me. I started taking a prescription nsaid for arthritis several years ago in addition to the supplements because as I got older I got stiffer and it hasn’t helped near as much as when I first took the supplements

  • @mjanebautista9477
    @mjanebautista9477 5 місяців тому +2

    Dr.Peng, thank you so much to your such a good information...

  • @nexxterra
    @nexxterra 7 місяців тому +10

    I love how the study says "in the short term" I have never been under the impression that these were beneficial unless taken for a while...

    • @heleneikerenkotter2950
      @heleneikerenkotter2950 5 днів тому +1

      This is not a supplement that works short term. It takes time for it to work to feel a difference. It is a long term supplement. It took a long time to develop worn painful joints and it takes time for Glucosamine, Chondroitin and MSM to help in the healing process. We have become a society of instant gratification. The body heals but not in an instant. An ounce of preventation is worth a pound of cure . Look at medical studies with a jaundiced eye. Who is sponsoring the study?

  • @triston5540
    @triston5540 5 місяців тому +6

    Great video! I have psoriatic arthritis. I’m on a biologic. I also have developed chondromalacia patella. These supplements I assume are tested by themselves not with any added rehab exercises. My hypothesis is that combination of these with a proper workout plan designed to promote cartilage health might increase the rapidity and total gains seen in the injury.

  • @venenareligioest410
    @venenareligioest410 5 місяців тому +10

    I remember reading an academic paper which broadly said that daily Glucosamine with chondrites was as effective as ibuprofen at releasing pain. With the added benefit that the analgesic effects did not reduce over time, as Ibuprofen does.

  • @MrLeedebt
    @MrLeedebt 8 місяців тому +20

    For me, glucosamine was a miracle. But probably not for everyone. I started a job delivering meat in my 50's. I would jump off the back of the truck, trying to give the impression I was young again. After a few months, my hand and knee joints were extremely stiff and painful in the morning when I woke up. I started taking glucosamine and it brought immediate relief. Because I had worked these joints for only a few months, maybe it would be different for say a carpet layer or bricklayer, who may have done it all their lives. I kept taking them, even after leaving the job after 10 months.
    After three years I changed brands and it seemed to produce blood thinning and low blood pressure, so I ceased taking the glucosamine. Amazingly, I felt as good as I did prior to doing the job.

  • @brucetownsend691
    @brucetownsend691 4 місяці тому +7

    I have found taking the Kirkland brand Glucosamine Sulfate, Chondroitin and MSM works for me. I just take 2 tablets each night. If I stop this routine I start getting arthritic pain again, so I keep it up. (Before getting on to this combination, I was using just Glucosamine with good effect, provided it was the more expensive sulfate rather than the cheaper hydrochloride form.)

  • @garygauthier1551
    @garygauthier1551 3 місяці тому +3

    I also have been taking glucosamine and chondroitin with MSM since 1998 ! At that time I was suffering with pain and stiffness in my right hip, my family doctor ordered a X-ray and found that I had moderate to severe joint degenaration in my hip. He suggested that I could try glucosamine and chondroitin with MSM. I also would see Chiropractors for neck & hip adjustments. After about 3 weeks I could feel my mobility had improved as well much less pain . Not only did I get improvement in my hip but also my neck issues disappeared.
    Just to mention that Veterinarians also prescribe glucosamine and chondroitin to horses & dogs that have mobility problems where noticeable improvement is seen !
    One more thing that I think needs to be said is that glucosamine and chondroitin won't work if your joint is bone to bone.

  • @maluell738
    @maluell738 Рік тому +4

    Thank you very much Dr. Peng for the very useful lecture. From my own experience Glucosamine /Chondroitin as long term supplement helped me in summer months. Unfortunately, I suffer from extreme pain during Autumn/Winter season. So I tried with Hyaluron injection once a week all in all 5x to which the Orthopedic told me I can have up to 10 injections yearly. To date I have none or just tolerable pain during Autumn/Winter time.And that saved me to date from having artificial knee joint.

    • @JeffreyPengMD
      @JeffreyPengMD  Рік тому +3

      Awesome, thanks for sharing

    • @maluell738
      @maluell738 Рік тому +1

      @@JeffreyPengMD I thank you Dr. Peng. I gained additional knowledge following your Vlogs. 👍👏

  • @michaelcale272
    @michaelcale272 6 місяців тому

    It appears that this helps my wife greatly in regard to joint pain

  • @paulmaglio9254
    @paulmaglio9254 Рік тому +1

    I take Amlodipine. That and my Don Joy unloader brace are total game changers for me.

  • @readthebook55
    @readthebook55 Рік тому +2

    Thanks for this helpful information.

  • @armerwillenbring4732
    @armerwillenbring4732 9 місяців тому +11

    Several years ago my left knee hurt so much I couldn't go up stairs. I saw a knee surgeon who said nothing can be done and I should schedule knee replacement. I asked to have a PT appointment. He said 90% of my knee pain would go away in 3 months if I did the ankle and hip exercises he recommended. I did and my knees are still pain free. I use Glucosamine and MSM just for insurance. I regularly do the ankle and hip exercises. My hips and ankles were extremely weak before doing the exercises. Bottom line, define the problem before scheduling treatment.

    • @jondowling720
      @jondowling720 4 місяці тому +1

      Be very interested to know exactly which exercises you were prescribed if you don’t mind. Thank you

    • @debritukidane8163
      @debritukidane8163 2 місяці тому

      😅

  • @etsout
    @etsout 16 днів тому +1

    They've helped my pain greatly.

  • @michaelh2797
    @michaelh2797 Рік тому +6

    I agree with digital.mente. I've been taking Osteo Bi Flex for years. I've tried other brands when the store was out, but they didn't work as well. And if I run out, I can really feel it!

    • @JeffreyPengMD
      @JeffreyPengMD  Рік тому +4

      Glad you found something that works for you!

  • @sionitacarnen9053
    @sionitacarnen9053 11 місяців тому

    Thanks immensely this beneficial video. Helpful . ❤

  • @bestsk8eva
    @bestsk8eva Рік тому +1

    Thank you Dr Peng for the info 🙏I'm your new subbed!!!!

  • @michaelstagar525
    @michaelstagar525 Рік тому

    Excellent stats-peer review!

  • @stevec8861
    @stevec8861 4 місяці тому +7

    Been taking Osteo Bi-Flex or generic triple strength equivalent for decades after osteoarthritis started in my hands in early 40s. Works great. However, I take 2-3X what label says (2 pills per meal vs. label dose of 2 pills per day with food), which is also 2-3X dose that doc here suggested near end of video. At lower dose, my joint pain quickly returns.

  • @00708046
    @00708046 3 місяці тому +5

    My experience taking Condroitin and glucosamine
    (g & c)together took time (several months ) but performed 3 repairs for me .
    1/ I had a tear in my miniscus (knee) causing clicking and locking up with pain .
    2/ My big toe was locking up and bending my foot in normal or quick walking was very painful .
    3/ I tore a tendon in my little finger knuckle .
    By taking g & c 2 times per day for 4 months my toe suddenly made a loud click . I exercised it back an forth further clicking . I was able to walk and run again without restriction and pain .
    My knee stopped locking up and clicking after 6 months .
    I stopped taking my 2 doses and my toe locked up again after 2 months so I took g & c again and it disappeared in days . I would take
    g & c for 2 days whenever my toe would lock up .
    My knee remained healthy for nearly 11 years when after kneeling on a hard floor for 5 minutes doing repairs I acquired a new clicking not miniscus but more like a tendon that was sliding out of its normal place and rubbing badly .
    Im working on that with g & c and limiting the incorrect sliding by using elastic bandage when exercising now .
    I also had the same issue in my little finger knuckle . I would bend it but could not straighten it . I wrapped it to keep the tendon from sliding to the side of the knuckle and took g&c and in 2 months regained normal function .
    Glucosamine with Chondroitin has helped me fix tendon /ligament damage , arthitic joint lock (big toe) and repaired a torn miniscus in my knee so far .
    I would say that it has really helped make repairs in my body .
    After its already in my system , I only take it when joint damage occurs for brief periods .
    It seems to work for a few months after .
    I feel that it is helping the damage to reattach itself and mend back to its normal .

  • @marilynjackson5752
    @marilynjackson5752 3 місяці тому

    Thank you so much. I'm starting this today.

  • @fatoomgierdien110
    @fatoomgierdien110 9 місяців тому

    Thanks for a great video. 👌🙏🤲♥️

  • @josephabdilla1383
    @josephabdilla1383 Рік тому

    Thanks
    Very helpful

  • @serenity8475
    @serenity8475 Рік тому +11

    Thank you for your research and all you do to inform us. YOU ROCK! 🙌 BTW: I have been taking it for awhile now and it is deff God sent🙏🙏🙏

  • @briansmale5457
    @briansmale5457 8 місяців тому +2

    I've tried just about everything known to Man without much success, i then tried Green Lipped Mussel from NZ & have found a great improvement :) I gave everything i tried 12 weeks & if i didn't feel any improvement i moved on to another supplement, the green lipped musssel showed improvement with in a few weeks.
    I've been taking it for about 2 years now & i have to say i'm really impressed with the results.

  • @sable2146
    @sable2146 4 місяці тому +7

    4:13 started taking a glucosamine and chondroitin for joint achiness a few years back and definitely noticed they have a delayed which is easy to overlook both going on and coming off (about effect 3-5 days for me). That these also act to address inflammation helps me to put in perspective why they work for me.

    • @lopezb
      @lopezb 4 місяці тому

      Yes, agreed. G and C with HA and collagen, the last 2x-day. Right hip pain almost gone. Still cant sit lotus position, but now I walk 40 min/ day with no pain. Initially 1 year ago I couldn't walk 1 step w/o pain, and was taking acitaminophen to sleep- which is terrible for liver.

  • @mwilliams-castillo9609
    @mwilliams-castillo9609 Рік тому

    Great info thanks for sharing , my doctor told me to use that

  • @Rockdoc2174
    @Rockdoc2174 4 місяці тому

    I have found that Glucosamine and Chondroitin work well with the osteoarthritis in my wrists. I was taking Glucosamine alone for some time before joint pain led to a referral to the local hand clinic. They confirmed the loss of cartilage between the lunate and capitate bones and recommended adding Chondroitin to my intake. Since then the wrist function has improved greatly and I have no pain at all.

  • @rameshnamdhe979
    @rameshnamdhe979 Рік тому

    Thanks for important information

  • @dcspangler8025
    @dcspangler8025 7 місяців тому +5

    Thank you for this post. I see that, along with the Glucosamine/Condroitin (G/C) some combinations include Methylsulfonylmethane (MSM). So how does this alter the equation? The majority of these supplements are manufactured using shellfish. There are some that are shellfish free, created by fermentation, I believe of corn. Further, what roll do GMO foods play? Both in causing inflammation in the first place and how the supplements manufactured with them differ in outcomes.
    Lastly, what about all the "other" ingredients? Magnesium stearate. stearic acid, etc. and how could they possibly alter the findings?

    • @thebrowns5337
      @thebrowns5337 4 місяці тому

      Microplastics and particle pollution - something we all have and cannot limit exposure to, lead to chronic inflamation. These have been found in umbilical cords so pass from mothers lungs into babies blood. We are setting ourselves up for shorter lives with more suffering. Ditching plastic and fossil fuels is needed to help our grandchildren.

  • @BradiKal61
    @BradiKal61 3 місяці тому

    Started getting knee and joint pain in late 40s (after being put on statins for high cholesterol, and was told by friends that they felt statins were the problem). After stopping the statins mist of the effects seemes to decrease but not disappear. Doctor later recommended glucosamine & C) which Ive been on for almost 5 years and joint pain and weakness feels much better but I can't say my regimen is a guaranteed success. Thanks to Costco prices my G&C costs are low so I keep taking it.
    The recent discussion about unknown higher levels of microplastics in bottled water may explain a LOT of health issues and I hope THAT research ramps up immediately.

  • @raymondlanier1112
    @raymondlanier1112 3 місяці тому

    This supplement saved my life

  • @SS-jb8wj
    @SS-jb8wj 4 місяці тому

    I knew I had arthritis in my knees and the specialist said I would need a knee replacement down the track. In February 23 I started weight lift training. I now have no pain in my knees and I have ditched the cane. The replacement diagnosis 10 years ago. The weight lifting has built up the muscles around the knees supports the knees.

  • @StephenfromChch
    @StephenfromChch Рік тому

    Very helpful.

  • @faridasukra8570
    @faridasukra8570 8 місяців тому +1

    Thank you so much ❤

  • @mikelanglow-bi2sv
    @mikelanglow-bi2sv 7 місяців тому +1

    THANKYOU. Respect -

  • @shrinandan3458
    @shrinandan3458 11 місяців тому +21

    Dr. Peng, Thanks for a very informative video. My personal experience is that the two meds when combined with MSM are very beneficial. I'm a 78 year old male with a family history of osteoarthritis. MSM definitely adds to the effectiveness. More studies should be done with the trifecta. I am living proof that it works.

    • @JeffreyPengMD
      @JeffreyPengMD  10 місяців тому +3

      Thanks for sharing

    • @kenhoward3512
      @kenhoward3512 7 місяців тому

      And the next question would be whether the chondroitin could be supplanted by MSM? I've been taking glucosamine with MSM for 23 years. As always: "More studies are needed..."

    • @revathik9225
      @revathik9225 4 місяці тому

      @shrinandan3458 Which brands of glucosamine and MSM do you use?

  • @tlmqp1426
    @tlmqp1426 3 місяці тому

    Wow, that was a mouthful. Thanks for the vid. It would be also interesting and helpful to know the exercise and lifestyle habits of those in the study, as well as the use of G & C in terms of preventative benefits before any onset of osteopetrosis. People may not be incorporating these supplements and/ or a healthy diet and/ or an exercise regime into their routines. Rather, as in the scope of this video, G & C serve as a potential remedy to treat the effect of joint pain; whereas, these supplements may play important roles in preventing joint pain in the long term. If they do, which is likely, their effectiveness should be measured along with diet, exercise, age, and even hereditary factors. The premise here is supplements in the after-the-fact, rescue role, and we just aren’t supplied with the other variables. Sports medicine is about treatment of pain in part, but hopefully more so about investing in being and staying active, which is proactive.

  • @brianbanks3044
    @brianbanks3044 3 місяці тому

    i take both Gluc and Chon and Syn Flex for 20 yrs...I stopped the synflex for a month and my knees started hurting...guess what, I went back on synflex and all the pain went away....I will take both for the rest of my life

  • @cynthiagonzalez658
    @cynthiagonzalez658 4 місяці тому +1

    Hooray for those to whom G/C worked.
    Worked for me for a few weeks, then the pain all came back.
    BTW, same experience with Meloxicam so maybe my liver just is super active in discarding meds

  • @lynettamurdoch5443
    @lynettamurdoch5443 5 місяців тому +3

    I used to take the combined glucosamine/chondroitin, but then read that the one of them - I don’t remember which one - made no difference in studies so I quit and started taking MSM/chondroitin(?). Eventually, I started taking only the MSM. I really don’t notice much difference with any of the combinations - or when used alone and may quit. I do take the fish oil, or krill oil. I think it helps - but mostly, my first noticeable difference was in my thinking/brain. Lately, I’ve discovered red light therapy and I’ve been using a band that wraps around my back, hip or knees, and recently, my shoulder. It has made the most noticeable difference.

  • @MadDawg-bp5wt
    @MadDawg-bp5wt 4 місяці тому

    The first study mentions was has no effect on 'short term' pain and function, the other studies appear to look at a longer view .... glucosamine & chondroitin is a long term play. After years of knee pain (not arthritis) it took a few months of glucosamine and chondroitin for the pain to leave, and function improve.

  • @johnmontana4898
    @johnmontana4898 7 місяців тому

    I've been taking it for almost 30 years.the hyaluronic acid. Keeps my skin from wrinkling. I'm 73 years and of course. You gotta exercise. I do some running also.

  • @Omegawerewolfx
    @Omegawerewolfx 3 місяці тому +3

    For my knee I do mobility exercises and strength training. My diet is pretty high on anti inflammatory foods too. Still have some bad days but I'm doing good. I'm not one of the people just popping pills and then claiming they work without any data.

  • @jeanwang2475
    @jeanwang2475 7 місяців тому +1

    Hi Dr. Peng, I'm 61 now, after I seen the video, I'm curious to know if it's the right thing for me to take.
    When I go up or down the stairs, my knees are painful, and as I walked too long it's also in pain

  • @user-fh4xq2ig7z
    @user-fh4xq2ig7z 3 місяці тому

    30 years ago I tore my ACL and got a classic bucket handle meniscus tear which was shaved smooth. Surgeon warned me I would have osteoarthritis there within 20 years. At year 19, the grinding started (great prediction by surgeon!). After confirming the arthritis with my doctor, I started taking glucosamine and chondrointin, but at 1/2 the recommended dosage. Within 6 months, the grinding went away and stayed quiet for 8 years. I did stop running (switched to cycling) and high impact exercises (I now teach indoor cycling and pilates). I did an accidental experiment when I tried to save money by buying gluchosamine without the chondrointin. Within 2 weeks, I had sharp pains start, so I added the chondrointin back, and the pain diminished within a month. I have now doubled my dose (which is the normal recommended daily dose) to maintain relatively pain-free living (as long as I avoid fast movements and high impacts). The combo really works! Are higher dosages than the recommended daily dosage safe?

  • @krefcenz
    @krefcenz Рік тому +6

    Great video. It’s really helpful to get the most up-to-date studies. I was wondering if you could do a review on a recent treatment for the arthritis call GAE. Genicular artery embolization. It is a technique developed in Japan, where they insert a catheter into your artery and inject a dye to pen point inflammation inside the knee joint. Then they release small particles to block the arteries, feeding the vascularization. some of the data coming out of UCLA. Impressive up to three years. I was just wondering if you had any thoughts. I’m currently doing PRP with hyaluronic acid injections staggered. I’m wondering if this new GAE could be an adjunct for me. Thanks

    • @JeffreyPengMD
      @JeffreyPengMD  Рік тому +7

      Genicular artery embolization and genicular nerve ablations are promising treatments but need to be studied more. These would be more for symptomatic relief and would not have the disease modifying effects (to my knowledge) that PRP may potentially have. I think it's an option worth exploring if other treatments have not worked and someone does not want a knee replacement surgery. My go to treatments right now include a combination of some or all of the following: diet, exercise (cardio+strength), PRP injections, supplements, and potentially trigger point injections if myofascial trigger points are present.

    • @megakwong6822
      @megakwong6822 10 місяців тому

      @@JeffreyPengMD 7:25
      😊

  • @visforvegan8
    @visforvegan8 4 місяці тому

    Based on this, I'll continue to use it for my dog who's torn both his ACL's.

  • @gcea123
    @gcea123 Рік тому

    My own independent study over past 10 + years. Glucosamine Chondroitin MSM helped my knees but not my hip.

  • @marilynroper5739
    @marilynroper5739 6 місяців тому +2

    I knew after 1 bottle that I would be using this. I’m sure it helps that I’m low carb and do strength training 6 days a week.Thanks for the detailed review, Dr Peng!

  • @georgehugh3455
    @georgehugh3455 4 місяці тому

    I took glucosamine and condroitin for my knees a decade ago and inexplicably started to get pain in both big toes. Tried it again (just two doses) two years ago and it happened again...and it lasted a long time. No mas.

  • @Seija729
    @Seija729 4 місяці тому

    helped with knee pain and back pain. i only take it when pain flares up so body doesn't become dependent, works every time.

  • @cynthialorenzo9376
    @cynthialorenzo9376 7 місяців тому

    That it works also for meniscus problem..

  • @user-qn8xe8os4x
    @user-qn8xe8os4x 2 дні тому

    I have been taking Glucosamine on its own, which works really well for me. I don’t take Chondroitin as I have a bad reaction from it.

  • @d.c.9895
    @d.c.9895 8 днів тому +1

    I was taking NAC for some flue symptoms and it fixed my knees, so now I'm taking NAC everyday and my knees are back to a 20 years old athletic guy

  • @Commiefornia
    @Commiefornia 4 місяці тому +3

    Beginning in my 40s my right knee didn't have pain but rather felt loose. When I stressed it, like running for a just a very short distance it would again, not hurt but felt even "looser". When going down steps it would pop when I bent that knee. I knew I needed to do something or I was going to eventually have to do knee replacement.
    I began taking a shellfish based liquid glucosamine/condroitin/MSM and I began feeling a positive change. I tried other types of powder glucosamine and eventually I would have the same loose feeling in my knee. I went back to the shellfish based liquid glucosamine and my knee would get better. I concluded that shellfish is the best source of glucosamine if you're not allergic. I've been taking a shellfish based gummy glucosamine/condtroitin/MSM supplement and it's been working just as well as the liquid, but I don't have to worry about refrigeration.

    • @smarzig
      @smarzig 2 місяці тому

      what brand?

    • @Commiefornia
      @Commiefornia Місяць тому

      @@smarzig I was using Flexicose. But when my old fridge stopped working a couple times causing me to dump a couple of opened bottles I switched to gummy glucosamine since they don't have to be refrigerated.

  • @Rosebie88828
    @Rosebie88828 3 місяці тому

    I agree with you doc base of my experience

  • @pauljmey
    @pauljmey 7 днів тому

    One or both of those is known to block glucose uptake in the gut. People with metabolic disease typically have greater pain/burning sensations when exposed to sugar/carbs, so that's a mechanism that would apply depending on when you ingest relative to a meal.

  • @mr.nonamanadus4463
    @mr.nonamanadus4463 4 місяці тому

    I slipped on ice and tore up my ankle, ended up going to the physiotherapist for an evaluation (this was six months after the accident). The reason was my ankle was stiff in the mornings and it took ten minutes to loosen it up.
    I was recommended this supplement and after taking it for three months I noticed a improvement (took it for another three months before discontinuing).
    It has been twenty five years later and I have absolutely no issues with my ankle.
    Now I am not sure how long a severe sprain regardinging the ankle takes to heal but I can honestly say taking the supplements did not hurt.

  • @robohippy
    @robohippy 3 місяці тому

    Prior to getting bilateral hip replacement and one knee replacement, I tried several different brands of each of clucosamine and chondritin, and as far as I could tell, they didn't do anything to relieving joint pain. It was long enough ago that I don't remember if I tried them together. There could be multiple reasons for them not working, including how severe my issues were.

  • @saralakushwaha1180
    @saralakushwaha1180 8 місяців тому

    Thank You 👍👍👍

  • @abradfordajb
    @abradfordajb Рік тому +10

    I'm presently using a product from Solgar which combines, in 3 daily tablets, the recommended mg levels of these two nutrients, integrated with 1,500 mg MSM & 300 mg of their formulation of "Biocell Collagen II" (180 mg Hydrolyzed Collagen II, 48 mg Chondroitin Sulfate, 30 mg Hyaluronic Acid). I also drink a daily scoop of a collagen peptide powder mixed in water.
    My objective is focused on rebuilding cartilage rather than simply reduction in pain. Knee cartilage destruction results in damage to the meniscus. In theory the meniscus can heal, but degenerated cartilage will just continue to "grind" the meniscus like sand paper. So, the goal is to reduce degeneration of cartilage.
    I plan to continue on this formulation for 1 year and see where it takes me. My knee arthritis does not produce chronic pain, though most days low to moderate discomfort. I am 70 yo and exercise consistently including a return to measured weekly running. I am interested in reading your thoughts on this regimen.
    Thanks for your informative posts .... much appreciated.

    • @JeffreyPengMD
      @JeffreyPengMD  Рік тому +1

      Thanks for sharing!

    • @SKs.
      @SKs. Рік тому +2

      Good video. Extremely informative. Thank you

  • @retiredlogman
    @retiredlogman 4 місяці тому

    It works for me. It takes a few weeks initially to feel the difference. User of over 30 years. Study has ended.

  • @Mickchillagegainford01
    @Mickchillagegainford01 3 місяці тому

    I'm 55 and ride BMX bikes on and off for the last forty years. I started with knee pain about three years ago, much physio, insoles for my flat feet and the pain came and went. in October of 2023 the pain retuned and I got an MRI scan in early 2022 , result onset of osteoarthritis, I've been recommended Glucosamine and have been told it could take up 6 to 8 weeks for the pain to go away. I'll try it and see if there is any improvement. If not I'll look to alternatives. Missing my bike riding a lot now.

  • @chirho777
    @chirho777 День тому

    I've been taking thorne joint support nutrients with glucosamine and msm with curcumin, bromelain and boswellia but now will be buying thorne glucosamine & chondroitin and try that out. Haven't really noticed a difference with the support nutrients as I was just told I have mild arthur and ostio. I exercise regularly. 🙏🏽

  • @motherof1132
    @motherof1132 3 місяці тому

    My knee was bothering me when I was in my 30’s. The doctor told me my cartilage had gone down. So I couldn’t even kneel in church to pray nor change my baby’s diaper. I took the Glucosome Chondroitan. I took it for just a couple weeks. The pain went away and I never had to take it again

  • @Desperado3248
    @Desperado3248 4 місяці тому +17

    I was skeptical at first, as a physician. I tried a short course of Glucosamine / Chondroitin in the past with little relief. I had been active, going to gym, hiking , martial arts and work. Sudden onset of arthritis in my k red was extremely painful. Tried nsaids, then knee injections with steroid once then two injections with hyaluroninase gel. First gave some improvement. Wore off in a few weeks. Second was not terribly successful, needed, nsaid. Started combination Glucosamine/Chondroitin and relief started in about 3 weeks, and is better entering my second month. I am walking, with my dog which was difficult, not getting pain at rest bit driving, can do more squats and horse stance posture workouts , and able to perform martial arts kicking again. A study looking at poor response from gel with addition of Glucosamine/Chondtoitin. I was looking at knee replacements , which now do not appear to be necessary. I will follow up with repeat k we c rays to see what status of arthritis changes are

    • @Sirrehpotsirch
      @Sirrehpotsirch 12 годин тому

      I'm encouraged by your post! It's been four months. Care to report on your progress? Still positive about G and C? Thanks.

  • @harjitkaur5407
    @harjitkaur5407 11 місяців тому +15

    I have been having knee pain..later diagnosed as osteoarthritis for almost a decade. The doctor suggested surgery but I did my own research on what is effective for me.. Collagen, omega 3, boswellia with turmeric and pepper besides glucosamine + chondrotine +MSN.. Very very effective for me.

    • @JeffreyPengMD
      @JeffreyPengMD  10 місяців тому +1

      Thanks for sharing

    • @revathik9225
      @revathik9225 4 місяці тому

      @harjitkaur5407 which brands do you use?

    • @harjitkaur5407
      @harjitkaur5407 4 місяці тому

      @@revathik9225 swissmed omega plus 1000mg , Himalaya shallaki (boswellia),

    • @rit20095
      @rit20095 2 місяці тому

      Which brand r u taking?

    • @harjitkaur5407
      @harjitkaur5407 2 місяці тому

      @@rit20095 as of present I am only taking boswellia Himalaya brand and omega 3. Omega Plus Swiss med . Has cut down on the rest of the supplements. Now maintaining with only those two.

  • @phyllissirois2118
    @phyllissirois2118 3 місяці тому

    I will try ty

  • @dannydelatorre7122
    @dannydelatorre7122 8 місяців тому +16

    I have had DDD in one of my lower back discs, and last Sunday I had a massive flare up. I had extreme pain and could not stand up straight, couldn’t sleep well, and could not walk normally or even bend over without pain.
    The first morning following the day I took glucosamine and Chondroitin, my pain is basically gone. The pain level went from a 10 to a 2.

    • @vineysharma8245
      @vineysharma8245 7 місяців тому +1

      How are you doing now ?

    • @Beau1990
      @Beau1990 5 місяців тому

      I have DDD too and this gives me hope.

    • @garrynorth6199
      @garrynorth6199 4 місяці тому +1

      How much G/C were you taking, I’ve just started taking 2 capsules a day for my osteoarthritis and hoping it helps after a few weeks.

    • @ryanyunuss572
      @ryanyunuss572 4 місяці тому +1

      Hi so recently, i started feeling a low back pain untill i figure it out it was my sciatica never and my friend whos a personal trainer advised me to take msm glucosamine + magnesium + amino acids, fun fact i started yesterday and was i was feeling pain yesterday at night, today i woke up with a almost no pain 😅 its crazy but its true, i will keep taking it and see how i feel in the next few weeks

  • @JSWilliamssr
    @JSWilliamssr 6 місяців тому +5

    That study is completely wrong. My Basset Hound has arthritis and nearly could not walk. We started giving her glucosamine & condroitin and she improved on the very first day. (We didn't tell her what it was, so no placebo effect :) ). She has been taking it for about 3 months and her improvement has been consistent and dramatic. She is running again.

  • @santhoshpt5630
    @santhoshpt5630 Рік тому +2

    Cartirise plus is very effective in my case. Having meniscal / cartilage damage led to initial arthritis. Physiotherapy with regular exercise with medicine improves condition.
    Your videos are outstanding among all knee related videos available across globe...👍👍

    • @JeffreyPengMD
      @JeffreyPengMD  Рік тому +1

      Thanks for the comment and support!

    • @ashokghose51
      @ashokghose51 Рік тому

      Very informative.

    • @rit20095
      @rit20095 2 місяці тому

      How r u now?I have been diagnosed with mild osteoarthritis of knee n have meniscus tear.How long did it take u to heal?

  • @larrym2434
    @larrym2434 4 місяці тому

    The cited study said specifically, "in the short term." I think a completely different, and more relevant question is, "Does glucosamine chondroitin help in the long term with consistent use?" In my experience, it doesn't help much in the short term, but IT DOES HELP when taken consistently in the long term.

  • @keithbutcher5386
    @keithbutcher5386 19 годин тому

    I take turmeric, glucosamine, chondroitin. All help my OA, but just started on Hyaluronic Acid. Results are stunning.

  • @user-ky7js5uv9h
    @user-ky7js5uv9h 3 місяці тому

    Anecdotally, I noticed a definite lessening of joint pain after starting glucosamine/chondroitin several years ago.

  • @narenmenon6906
    @narenmenon6906 7 місяців тому

    Did they use the "sulfate" form?
    I have not taken "pain killers" in many years.

  • @Earthstein
    @Earthstein 3 місяці тому

    Thanks Doc. Very helpful to me. Mr 71yo .

  • @lisag18
    @lisag18 4 місяці тому

    I took this for many years then i started using fish oil. I feel a lot better overall. Fish oil helps with everything, not just achiness and arthritis. It helps the body as a whole. Curcumim is good, too

  • @sandramurkerson9041
    @sandramurkerson9041 7 місяців тому

    More about MSM PLEASE

  • @boonkailee8237
    @boonkailee8237 6 місяців тому

    Hi doctor, please advise can i take glucosamine (include MSM & chondroitin) and boswellia together?

  • @pietrocantuccini5584
    @pietrocantuccini5584 3 місяці тому

    I've read on Pubmed, which I regularly use for checking up on things, that in a good sized trial the dispensed combination did not help the patients with knee osteoarthritis. I didn't doubt the results but thought they selected the wrong clientele. Namely already long-time sufferers. Said report did not mention how long participants have had their ailment. When one of my knees once started being painful (first on stairs only, then on flat ground after 3 more weeks) my GP wasn't helpful by offering just painkillers. Somewhere I had read that the combination with the recommended dose helps 85% of sufferers after ca. 3 weeks., so I tried it. Bummer, no change. As I didn't want to waste money I undertook to finish the bottle. In week 5 the painful inconvenience was gone. Good thing I didn't let it linger for months or longer. Then I reduced the intake by and by until I forgot to take it. There are still a few occasions a year when the knee starts playing up again. But two or three days of supplementing fixes it again for at least 3 months. (Can't use the natural method as I'm not fond of greasy fish)

  • @abrianec
    @abrianec 8 днів тому

    There is a big difference between repairing a damaged joint and maintaining joint health over the long term, many studies have focused on short term repair and many are very poorly designed using vague metrics- one widely reported study used vague measures of patient evaluated discomfort in patients with serious joint damage over a short period. Many people I know take supplements for maintenance and inflammation reduction- these are very active people with osteoarthritis. I take glucosamine/chondroitin/ASU as formulated by Dr Theodakis who claims clinical evidence for ASU is stronger than for G -C, even given clinically demonstrated benefits of G-C. I haven’t seen much on ASU in the popular media.

  • @user-ff9yk7ik2n
    @user-ff9yk7ik2n 5 місяців тому

    As suggested the "multi model approach" in your other video, will Glucosamine & Chondroitin work fine along with PRP injections?

  • @shunhingengco1171
    @shunhingengco1171 7 місяців тому

    what's your opinion about glucosamine chondroitin msm CREAM? any good?

  • @missfreshair
    @missfreshair 2 місяці тому

    how about eggshells. and other treatmemts such as prp, biocartilage, maci or arthroscopy seem to be less invasive. all promote the production of a vascular connective tissues/cartilage