Remarkable Science: Understanding lifespan and why aging might be reversible with Dr. David Sinclair

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  • Опубліковано 17 лис 2024

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  • @juliak2591
    @juliak2591 Рік тому +29

    I wish the interviewer would have asked more questions about the actual science of anti-aging than debating the anti aging concept.

  • @MarkZiegler
    @MarkZiegler Рік тому +33

    I would stick with PHD's for moderators.

    • @fr1571
      @fr1571 Рік тому +1

      Or at least somebody intelligent who is aware who she’s talking to. This is what happens when we put diversity before merit. Happened with our VP too. Normal these days.

  • @kingo55
    @kingo55 Рік тому +47

    David handled that interviewer expertly. She can choose to live a shorter life if she wants... not sure why she was so offended.

    • @thomasjust2663
      @thomasjust2663 Рік тому +7

      She got me confused as well, almost like because her father died, everybody must die then...weird

    • @JackSmith-kp2vs
      @JackSmith-kp2vs Рік тому +2

      @kingo55
      What are you talking about? Nobody got offended, they just debated a point that they disagreed on in a respectful and friendly way

    • @antoninanavarre9107
      @antoninanavarre9107 Рік тому +3

      @@JackSmith-kp2vs Calling a scientist in a podium discussion out for having a Peter Pan complex, without that being more than a passing remark and without arguing the point, really is a thing which can be best explained with a pretty severe shortage of social sensibility, or being pretty gravely offended, is my impression. It is a pretty rude thing to say.

    • @JackSmith-kp2vs
      @JackSmith-kp2vs Рік тому +2

      @Antonina Navarre
      Was she supposed to just ask him all the questions he wanted to answer? It’s the debaters job to ask questions that maybe isn’t the most comfortable for the other debater in order to have a healthy debate. Asking or saying someone has a Peter Pan complex is hardly an insult is it.

    • @Jessica-kk1cz
      @Jessica-kk1cz Рік тому

      @@thomasjust2663 Agreed.

  • @rebeccah1437
    @rebeccah1437 Рік тому +3

    Speak for yourself lady, I didn’t care for her attitude towards David. My husband died at 34 from cancer and I was his caretaker for years, I won’t be able to go though that again with the rest of my family members. His main point is to not die in a long and dragged out painful way where the person suffers in a living hell… she came off to me as passive aggressive towards him and he’s truly trying to help humanity. I like David, he seems really compassionate towards his loved ones that have suffered. I personally don’t believe we were meant to age this rapidly, life goes by too fast and humans used to live a lot longer

  • @Almost-Infamous
    @Almost-Infamous Рік тому +10

    This moderator made this discussion very awkward to watch.

  • @sherryrogers426
    @sherryrogers426 Рік тому +9

    While I appreciate the questions of the host, they could’ve been stated, and more polite, less devils advocate way. Dr. Sinclair came across as a completely gracious wonderful human being. A person you would like to be friends with. The host was in my opinion, not very professional.

  • @brett7077
    @brett7077 Рік тому +14

    This interviews was meh - David is great

  • @corinaglavan4528
    @corinaglavan4528 Рік тому +4

    Another amazing dialogue! Thank you.
    David, I hope you are right and that by following your advice from your research I’ll live longer, otherwise I haunt you! 😊
    I was joking. The truth is that I feel that I am reversing my age in following for the last two years your theories. Whether I live to 150 or die at 70 it does not matter, instead it matters the quality of my life that I am living. I’m very grateful.

  • @RajuGogul
    @RajuGogul Рік тому +9

    He has several points to his credits!!!! Mindfully reading or listening to his book “Lifespan: Why We Age - and Why We Don't Have To.” might give us deeper dive into his insights and for our practice.

  • @BarsandNightclubsAU
    @BarsandNightclubsAU Рік тому +8

    Probably best not to let this lady near a microphone for a while. My god.

  • @jonathanswellnesslab
    @jonathanswellnesslab Рік тому +1

    Bro... for 53, Sinclair looks amazing and excludes youthful energy.

  • @digitalsyanide1746
    @digitalsyanide1746 Рік тому +12

    Someone explain to me how sinclair looks like a Vulcan from start trek which is great due to their advanced technology and skills and Aubrey de grey looks and talks and has a name like a damn wizard if this is the timeline cern switched us to I am perfectly happy about this timeline with what is available in tech and possibly immortality lol

  • @johndoyle4468
    @johndoyle4468 Рік тому +15

    As always David Sinclair is awe inspiring. However the interviewer is totally crap. Surely someone could have found someone better to interview David. She had a lot of nonsensical questions.

  • @PattyRichardson1
    @PattyRichardson1 11 місяців тому

    David is amazing! Inspiring!!!!!

  • @milamaslen3594
    @milamaslen3594 Рік тому +6

    The interviewer represents the point of view that many people have. She does ask a lot of questions many so-called normal people ask when talking about aging and reversing it. And there is a widespread sentiment many people have that we are supposed to die or that aging is part of life or that it is natural, making it somehow good. Nature for many is associated with healthy and wholesome and right. Mind you, viruses and cancer and flesh-eating disease are also very natural, but we don't put them on a pedestal. Evolution has no mind of its own. It is a mechanism for survival and we really are the vehicle for genes. What happens to us - thinking, conscious, sentient creates the evolution doesn't care. We've battled the evolution for thousands of years now. By fighting diseases, by creating dwellings - safe, comfortable environments protecting us from weather elements, by taking care of our old who cannot hunt and gather themselves. We do care about survival past the age of reproduction. Aging is one more frontier on the path we are already on. But many are so used to the idea of aging, in many cases propelled by the ideas of Christianity, which says that is just another stop along the journey, that it shocks them to even think that that's something we can change. We do have a mechanism blocking the thought about our own death because it is too horrible to really think about. And I know some people make some kind of peace with it. But, I personally, will never do. I do think that however radical the idea of fighting aging is, it is just one of those important ideas we have to rethink and reevaluate and re-adjust to. Fighting aging will have a great pushback in society which will ask the same kind of questions - for example - what about God and soul and the end amount of resources. If this type of treatment became a reality there would be ethics committees and fears much worse than we have now about GMO, fears of inequality and overpopulation. But we already went through cultural changes that made unthinkable normal. We can do things right now that we would be shunned and put in jail for just a half of a century ago.

    • @gsferreira3048
      @gsferreira3048 Рік тому

      Vc esta equivocado em Ingleskkkk;esse tratamento ja existe e eu mesmo sou uma prova viva que parte da "ciencia" foge como o diabo
      Da cruz;se fosse vc adentraria
      Na telomerase e sirtuinas e mitocondrias e celulas tronco
      De cabeça;temos que entender que meu medico😂
      Dr Sinclair tira la suas moleculas "da cartola" ou como falmos em portugues
      Cachola e vou te dar uma informacao priviligiada;os super polifenois de Harvard
      Geram super celulas no nivel
      De celulas tronco;a vitamina
      B3 e outra que gera celulas
      Destas linhagem;o importante
      E saber que ja temos um asernal anti envelhicimento.
      Eu nao tenho medo de morrer
      Como vc por que eu creio
      Que a ciencia esta se multiplicando pela palavra de Deus!Daniel 12...

  • @gunjangupta6690
    @gunjangupta6690 Рік тому +7

    I agree. It was good that she was asking lot of "obvious questions" that may seem unfair to Sinclair's fan but are out there. It really helped clear up the air on lot of Elon-Musk-Style anti-David-Sinclair propaganda out there...

    • @rosalbadelriogarcia9598
      @rosalbadelriogarcia9598 Рік тому

      I'm glad you mentioned this!!! such an eye opener about the #humanity and #sympathetic #empathetic scientist research.
      I'm sure #ElonMusk too is correct on hid premised worries. The context of the science is based on lots of pharmaceutical biochemistry vs natural and optimized human nutrition. What is *the proper human diet* ? #LongevityProject
      #epsteinHarvardLab
      #AstronautGotBloodClots2018
      #anticoagulantTherapy
      #oxygentherapy
      #epigenetics
      #covid #mRND
      #CRSPRcas9
      #carnivoreCure
      #TheNutritionistDilema
      #whyWeGetSick
      #LiesDoctorToldMe
      #DrThomasSeyfried
      #DrDaleBrenesen
      #DrDominicDagostino
      #metabolicMind
      biohackers #timFerris
      #levels #agenomore

  • @ivascunicolae8920
    @ivascunicolae8920 Рік тому

    Congratulations to Lifespan!

  • @robynhope219
    @robynhope219 Рік тому

    Notice his choice of words "why aging MIGHT be reversible, NOT that it IS.

  • @lisanidog8178
    @lisanidog8178 Рік тому +3

    I don’t care how old Mr. Sinclair is. It doesn’t matter.

    • @lisanidog8178
      @lisanidog8178 Рік тому

      @@Phoebus_Apollo you can’t stop or delay age. You’re not going to look or feel like a teen your whole life. Life is hard young or old.

  • @selin-demi
    @selin-demi 4 місяці тому

    Young people do get cancer nowadays though. It didnt use to happen, but recently 20 year olds are getting cancer a lot more. How does he explain this?

  • @voiceanddrum
    @voiceanddrum Рік тому +1

    The pursuit of “anti-aging” is about kicking the can down the road as much as possible. Imagine maintaining the youthful health of your twenties well into your 40s. And imagine reproducing in your 40s and 50s rather than from your late teens to your thirties. Wouldn’t you be a much better parent? The gap in her understanding is that the additional years are on the front end…pre-disease. Moving a disease state to much later in the human experience and allowing our end to happen quickly instead of over the course of years. It’s painful to think that humanity might improve their plight in such a significant way, but not in time for her own parents. Nor for mine. Rather than the terrible bandaids applied at the end of life, the idea is to create a youthful level of health for much longer on the front end.

    • @antoninanavarre9107
      @antoninanavarre9107 Рік тому

      Well, reproducing in the 40s and 50s is a more or less individual choice. Most people chose not to do that, but that's because of social pressures and customs, which might change as a knock-on effect if aging is cured, but we could change them even now.

  • @hulamei3117
    @hulamei3117 Рік тому +3

    Peter Pan... major shade.

  • @wisdomclub888
    @wisdomclub888 10 місяців тому

    Similar to a Jordan Peterson interview, and handled well here as well.

  • @robynhope219
    @robynhope219 Рік тому

    I'm beginning to think this whole thing about slowing or reversing bio aging is bullshit. I bought the book and was enthused about it, but now skeptical. For instance, I took Metformin for a year and felt no different. In addition I took some of the neutraceuticals he recommends...no change in my chronic fatigue. A strict diet hasn't helped, either. Maybe I'm too old to expect a change. I'm on DHEA now and hope for more energy down the road. Alas, I had to quit metformin bc of bad side effects. And as far as NMN and NAD, they're way too expensive for the average person. Overall, this business of anti aging medicine is for the rich😢

  • @alessandrobalboa3536
    @alessandrobalboa3536 Рік тому

    amazing talks. the interviewer is amazing, all great questions

  • @rtnjo6936
    @rtnjo6936 Рік тому +2

    Nah, she's actually good. I first wrote angry comment, but it's better to ask hard questions. THank you!

  • @gsferreira3048
    @gsferreira3048 Рік тому

    Dr David por favor ja tem tradução de lifespam em portugues?

  • @slimbuttermilk
    @slimbuttermilk Рік тому

    I’m a living example of proof that aging can be reversed! That’s why I’m going through my second childhood😊

  • @TaniaSeabock
    @TaniaSeabock Рік тому +1

    I did not like this interviewer at all and thought it was just me. But after reading all the comments, it looks like I was not the only one.
    She made me cringe.

  • @yibichen
    @yibichen Рік тому

    Aging research is for over come death obstacle , it's painful when you grow old and got disease ,the most is death itself.
    Many old peoples were suffering this and these are not right for us to thinking about it is a right things got disease and death.
    I am gotting to call you if you already successfully in human.
    No matter what I am gotting to finish this research work.

  • @marionharris5952
    @marionharris5952 Рік тому +1

    Interviewer could have been better.

  • @andreamazzaferro5168
    @andreamazzaferro5168 Рік тому +7

    a waste of David’s time … and ours

  • @zack_120
    @zack_120 Рік тому +1

    Well, whatever and however much you eat less, you must have been eating enough energy and protein to allow you to get those biceps unless you've got ultra-thrifty genes. For people to believe what you said here you must explain this apparent discrepancy first.

  • @thebeautiestbeast
    @thebeautiestbeast Рік тому +3

    What is wrong with this woman ... She obviously never witnessed someone die in pain .... Dying is a real disaster ...

    • @Sciencetalks123
      @Sciencetalks123 Рік тому

      True!

    • @secretname2670
      @secretname2670 Рік тому

      First world privilege aye. In most modern countries morticians, nurses, volountaries and grave diggers (if they still exist) take care of the dying or the body, everyone just kinda awkwardly tries to not see the reality and forget what they gazed upon.
      Pathetic society

  • @thomasjust2663
    @thomasjust2663 Рік тому +5

    This woman was very annoying

  • @martaschaffner6709
    @martaschaffner6709 Рік тому

    En español, please

  • @kelliesiwicki7398
    @kelliesiwicki7398 Рік тому

    I can't take the echoing mic

  • @dover1129
    @dover1129 Рік тому

    i dont see any point in dying, so i hope we can get around that like integrating with AI or something

  • @frankwilliams3036
    @frankwilliams3036 11 місяців тому

    Why shouldn't we live forever?

  • @monag.769
    @monag.769 Рік тому +2

    The moderator doesn‘t seem to accept nor understand what Dr. Sinclair explains. She is also very negative…what a waste of time and energy.

  • @secretname2670
    @secretname2670 Рік тому

    David; "well we could heal aging as bodily decline instead of sticking a band aid on problems caused by aging"
    Interviewer; "then what would people die from? Someone should die"
    Well in my humble uneducated peasant's opinion , you shouldnt say out loud that other people should die, even if you want them to.
    She's also unprofessional constantly stopping sinclair mid-track and whatnot.

  • @VermontJayson
    @VermontJayson 9 місяців тому

    I’m half way through. This woman has asked terrible questions. I hope it gets better

    • @VermontJayson
      @VermontJayson 9 місяців тому

      3/4 of the way and she’s getting worse.

    • @VermontJayson
      @VermontJayson 9 місяців тому

      Maybe she’s religious because her questions seem very negative towards anything that might slow down the trip to heaven.

    • @VermontJayson
      @VermontJayson 9 місяців тому

      Ha! her final question shows why her questions generally suck. she doesn't want to slow aging. well great, wish I knew that for sure in the beginning.

    • @VermontJayson
      @VermontJayson 9 місяців тому

      Oh geez "he's with me" bloody hell why is she allowed to interview David?

  • @reneoyanadel3377
    @reneoyanadel3377 Рік тому +1

    The host the only bad thing in this video

  • @dorisford7313
    @dorisford7313 Рік тому

    Echo

  • @felipenajera787
    @felipenajera787 Рік тому

    What she wants.. it’s an ok I’ll make you young for free, because you need it .

  • @dv8760
    @dv8760 Рік тому +1

    Loved the interviewer

  • @lq4657
    @lq4657 Рік тому +1

    She sounds confused lol

  • @roberthadley4157
    @roberthadley4157 Рік тому +1

    Worst moderator ever!

  • @lq4657
    @lq4657 Рік тому +1

    She's trying too hard to sound smart

  • @FVLMEN
    @FVLMEN Рік тому +1

    She meant half a millennium not plural millenia. She was annoying.

  • @elvisburgerking8675
    @elvisburgerking8675 Рік тому +1

    46:25 my partner
    who'd have guessed ?
    longevity is irrelevant without reproduction of the species
    LOL

  • @bororobo7036
    @bororobo7036 Рік тому

    Dr is a dreamer with heavy vested interest between science/marketing and she is sort of intelligent, but boring to death.

  • @rg-cb2wd
    @rg-cb2wd Рік тому

    and now you can buy his subs for 5% less use the code scammer

  • @lisanidog8178
    @lisanidog8178 Рік тому

    So what you look younger than you are. So am I! So were all the ones on both sides of the family. I just have “good genes” as dad used to say. I started graying at 35. Not completely white at 63. Not a wrinkle, and I don’t do a thing. My joints feel like 90. I take aspirin and creak along the best I can. I’m not age obsessed like this society. No wonder no one enjoys life. You can’t beat the clock. We’re all gonna go eventually. It’s called life.

    • @DimensionPicturesAOT
      @DimensionPicturesAOT Рік тому +6

      Pessimistic and disappointingly one-sided opinion on the subject of living a longer healthier life

    • @lisanidog8178
      @lisanidog8178 Рік тому

      @@DimensionPicturesAOT not pessimistic at all. You can die healthy or sick. Getting old is just part of life. Get used to it. You can’t change it. You’ll eventually go anyway. In 5 billion years when the sun expands and swallows this planet understanding aging and trying to reverse it will be moot.

    • @123ChrisG
      @123ChrisG Рік тому

      We will eventually stop the ageing. And these anti ageing therapies won’t just delay ageing, they will regenerate the body, heal old injuries, heal joints, regenerate organs, regrow entire limbs, (we already can do this in animal models), heal the brain so we can think clearer like when we were younger, and so many other benefits. It is the future and it’s going to happen within the next 20 years.

    • @lisanidog8178
      @lisanidog8178 Рік тому

      @@123ChrisG give immortality then you got something. In the end you still die until then.

    • @lisanidog8178
      @lisanidog8178 Рік тому

      @@Phoebus_Apollo I just did. Quite interesting. Thanks for recommending something new to learn about.

  • @haydukethor
    @haydukethor Рік тому +1

    turned it off after hearing the host for a minute so annoying I’m out

  • @margaritaa5780
    @margaritaa5780 Рік тому

    David looks like his grandmama