Hacking the 3 Pathways of Aging

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  • Опубліковано 25 лис 2024

КОМЕНТАРІ • 655

  • @bradmolyneaux5883
    @bradmolyneaux5883 4 роки тому +53

    Just to vent to my vegan community: I came across a video from a channel that I followed for personal growth and inspiration but they have branched into health topics. They had a video about being young fit and healthy forever. The "doctor" was quoted early on saying that you have to eat a ridiculous amount on a plant based diet and compared quinoa and chicken breast. I don't know if we are ever going to properly educate the majority of people because of these propagated misconceptions. When I'm talking about plant based diets My parents still throw in "there are some things missing" it's like the information can't get past previous biases.

    • @rachelgoodkind6545
      @rachelgoodkind6545 2 роки тому +11

      Hi, there is an incredible bias against veganism in the omnivore world. It is true, studies show vegans in general are
      low or deficient in many nutrients which we need to pay attention to. I think this is the main reason for "failed
      vegans". However, the omnivore diet (and carnivore, keto, etcetera) are also low (or deficient in) several nutrients, but you
      never hear about this from critics of veganism. How about having your parents watch several of Dr. Greger's videos, and getting your parents to get a blood test and show them they are far from perfect!. I have been vegan 20+ years and humans are fearful of changing, especially away from animal flesh and blood. Here are some examples.....cheers
      pubmed.ncbi.nlm.nih.gov/26502280/
      pubmed.ncbi.nlm.nih.gov/34069944/
      nutritionfacts.org/video/omnivore-vs-vegan-nutrient-deficiencies-2/

  • @ryuji_chua
    @ryuji_chua 4 роки тому +181

    I found also that waking up in the AM super activates my Pikachu

  • @Pyriphlegeton
    @Pyriphlegeton 4 роки тому +32

    I don't particularly want to live forever.
    But as long as I'm healthy, I won't want to die. So that kind of follows.

  • @ericmeiselbach7416
    @ericmeiselbach7416 4 роки тому +118

    Read the book. Anxiously awaiting “How not to age” from Dr Greger

    • @foodguy3435
      @foodguy3435 4 роки тому +8

      I’m so excited for that book, I can’t wait!

    • @wcraca5
      @wcraca5 4 роки тому +10

      How not to age from someone that looks like a crypt keeper, no thanks

    • @irjake
      @irjake 4 роки тому

      Even knowing that it does not exist, I would pre-order it right now if I could.

    • @DannyStopMotions
      @DannyStopMotions 4 роки тому +11

      wcraca5 Sounds like your own judgements and mental health may be your first health issue to start with.

    • @IRosamelia
      @IRosamelia 4 роки тому +2

      I already read How not to Die and got How not to Diet, will get around to reading it before autumn 🍂🍁🍂

  • @shannonweymark2308
    @shannonweymark2308 4 роки тому +88

    Ugh. This was fantastically full of information and legitimate studies as usual 🤤👏🔥 Thanks for making my brain happy :')

  • @jelatinosa
    @jelatinosa 4 роки тому +9

    I don't know why but I found you very endearing in this video. You would make such a good professor, the way you talk and make complicated subject matter much easier to understand and digest. And you make it interesting with humor and a lightness about you. Glad people like you exist in the world.

  • @wlgeiger
    @wlgeiger 3 роки тому +3

    I love how you spend hours and hours reviewing all these studies and then you're nice enough to thank us for watching less than a 30 minute video. I have listened to a few of David Sinclair's videos. Great constructive criticism and review of his points.

  • @Annibals
    @Annibals 3 роки тому +5

    Mike's outstanding in breaking down broad matters involving overwhelming research to it's key points that everyone can understand and digest

  • @roku3216
    @roku3216 4 роки тому +39

    That's a pile of research, Mic. Thank you for doing it so we don't have to (also, I didn't know that I didn't know half of this).

  • @reishiman8440
    @reishiman8440 4 роки тому +42

    Thank you pikachu in the morning for keeping my mitochondria burning clean

  • @poogissploogis
    @poogissploogis 4 роки тому +40

    I learned a lot as always! Thank you for all of your hard work over the years Mic. All of your nutritional science has really helped me shut down all of the annoying criticisms of my diet and lifestyle that meat heads throw at me, and I've even changed a few minds: all thanks to your information! Keep up the hard work my friend!

  • @phatmonkey11
    @phatmonkey11 4 роки тому +26

    Thanks for your thoughtful, well researched videos, Mic. While I'm not yet totally plant-based, it's content like this that encourages me to keep plugging away.

  • @sparky9839
    @sparky9839 4 роки тому +19

    Thank you , I’ve listened to Dr. Sinclair many times and have maintained a healthy skepticism. It’s very interesting research that he’s doing but if something is tested on mice it doesn’t necessarily translate to humans. He does seem a little too focused on supplements and really doesn’t know much about nutrition either. You are the only one that has pointed out these flaws. ✌🏻🌱

  • @funnybribri1234
    @funnybribri1234 4 роки тому +18

    So excited to see this vid, Mic. I had a friend buy me Sinclair's book, Lifespan. Such a wonderful read. Look forward to hearing what you have to say!!

    • @radhablinderman2183
      @radhablinderman2183 4 роки тому +2

      I’m also a fan of the book and would love to know more on what Mic thinks.

  • @JulieOParkCity
    @JulieOParkCity 4 роки тому +66

    I’m in my 50’s and an ex-pharma rep but I wouldn’t take Metformin.

    • @Runpierre
      @Runpierre 4 роки тому +1

      Why?

    • @Greg-il8by
      @Greg-il8by 4 роки тому +11

      @@Runpierre the benefit listed is relative, not absolute, and the longterm side effects are not good. It's just a well-marketed product sold to doctors who don't know any better. Watch Dustin Rudolph and John McDougall on this.

    • @someoneusa
      @someoneusa 4 роки тому +6

      It's insane how many doctors are taking metformin for anti-aging. Ok, well, maybe not that insane -for them- since they are so obsessed with pharmaceuticals and not that into total body health. SMH. I've heard diabetes patients go on and on about side effects. So not worth it, we don't know enough. They just did a recall on a few metformin generics for cancer risk.

    • @msmreviews8408
      @msmreviews8408 4 роки тому +2

      They gave me that for fertility. Didn’t work. Still childless.

    • @gisenda
      @gisenda 4 роки тому

      @@msmreviews8408 me too

  • @wikjor100
    @wikjor100 4 роки тому +8

    Thanks for doing this video Mic. Grateful for all your research. I agree, staying away from drugs for longer life and being on a meatless whole foods diet is the magic pill for a longer lifestyle. I started a healthy lifestyle at 20 with meatless diet and mountain biking for over 35 years/ being 65 now with a BMI of 21 and a BP of 110/65 and resting HR of 47. And living longer now than most of my my grandparents who died of strokes and heart disease. Except for one grandmother who lived to be 98 because she also lived a healthy low meat lifestyle. I can truly testify that the lifestyle you have researched is truly the path to take. I look forward to many more years because of it. And I encourage anyone who wants to stay healthy and off of debilitating drugs and heart surgery when you get older to follow the lifestyle Mic has given us completely. And as to NAD and Sirtuins are stimulated form Sulpherphane found in high levels from broccoli and kale. I put a lot in my smoothies every morning.

  • @greggibbs3639
    @greggibbs3639 2 роки тому +1

    I'm 70 now. My father died at 44. One grandfather at 53. I take no medications and try to be a vegan, especially when I can fully control my diet. Your video's are great, as most of us do not understand all the science. But since I stopped working, exercise has decreased, as I used to bike or walk to work. So ... daily exercise...

  • @emily7198
    @emily7198 4 роки тому +97

    Wow... Metformin also has been shown to increase dementia when taking long term. So longer life, but at what cost...

    • @Fearzero
      @Fearzero 4 роки тому +5

      Exactly. I tried it and my feet started burning.

    • @BalHatase
      @BalHatase 4 роки тому +5

      Yes, using this drug to promote life extension is not a good idea

    • @DannyStopMotions
      @DannyStopMotions 4 роки тому +5

      Way too many reported side effects. Scary!

    • @sweetcaramelsmile
      @sweetcaramelsmile 4 роки тому

      I actually have to take this med. PCOS= insulin resistance. Stopped taking it and BLEW UP! That was on a less caloric diet and more active, smh.

    • @metalguru5226
      @metalguru5226 4 роки тому

      @@sweetcaramelsmile Glad it's working for you. Any side-effects in your case?

  • @kimscheuer8023
    @kimscheuer8023 4 роки тому +8

    Great video. Very thought-provoking especially about metformin. I would love to see a study on longevity on people who eat a WFPB diet comparing those who took metformin and those who didn't. I am waiting for those results before starting to take metformin myself as I am not diabetic.

  • @michaelboller5314
    @michaelboller5314 3 роки тому +1

    An alternative to Metformin would be Berberine. It increased lifespan in mice and is available as a supplement. However, there are many things that might increase lifespan (such as exercise, healthy weight, nuts, Omega 3, garlic, tea, coffee, berries, Chlorella, ginger etc).

  • @MattAngiono
    @MattAngiono 4 роки тому +26

    Still in my thirties, and just hoping I get to test these someday....
    Animal ag is destroying the planet so fast that I fear ecosystem collapse will actually be what determines our "longevity"....
    Vegans need to be deeply concerned with the environment (everyone does) but more so *environmentalists absolutely need to adopt veganism!*
    Enjoyable video buddy, keep it up!

    • @Hoppensagen
      @Hoppensagen 2 роки тому +1

      It's kind of a myth that animal agriculture is bad though, people always say they take a lot of water, but a lot of the water they take is actually just peed out onto the ground. It's not like if they drink 100 gallons of water they just keep it the whole time. They only keep what they need to maintain body weight. Same with the whole methane argument, it's really not as bad as people say. The real pollution problem comes from China and India these days. Especially huge plastic issues. I would say though, pasture raised farming is preferred. I would love to get rid of any corporitization of the food system. It would help farmers be free and not in debt. Also just keeping animals in feeding lots is horrible. You have to understand though these studies on meat are limited, we don't actually know if eating meat is as bad as a lot of vegans say. Eating bad processed meat sure, but a lot of studies on meat are following people who also smoke and make a bunch of other bad lifestyle decisions. People who are vegan are usually more health conscious and don't smoke etc.

    • @MattAngiono
      @MattAngiono 2 роки тому

      @@Hoppensagen you should look at the studies on land use.... they explain we could rewild an area the size of Russia back into natural biodiverse habitat, which would really help with both carbon absorption and stabilizing the climate. It would also help slow the mass extinctions already underway.
      But really, it's the whole impact of all these things put together, not just one variable. Land is by far the big one when it comes to animal agg though.
      People still act like we have no limits to our consumption and I still see people throw trash out the window and find it pretty much everywhere.
      We are just too stupid to realize we're killing our beautiful planet through our everyday decisions, and food is the biggest factor in that. We get terrified over a bad cold spreading around, but can't see the very obvious things we've done that are making the ecosystem break down. And somehow we think we'll just move to Mars if it gets real bad, which is even more absurd.
      I'm not sure we deserve this paradise and soon it'll be too late to do anything about the damage we've done

  • @kiesnutrition2809
    @kiesnutrition2809 4 роки тому +2

    30 studies! Really appreciate all the research that goes into these videos. Thanks, Mic. 🙏🙏

  • @猪憨憨
    @猪憨憨 4 роки тому +2

    So glad to see that ur channel has grown quite a bit! I remember how, 3 years ago, it had way too little attention for how good the info already had been. Keep spreading the truth brother, cuz you’re changing the world for the better.

  • @ade1963
    @ade1963 4 роки тому +19

    Dr Greger's book, How not to diet, explains at great length that you can activate AMPK without exercise - just take 2 tablespoons of vinegar per day (it doesn't have to be ACV)

    • @wcraca5
      @wcraca5 4 роки тому +2

      Yup, just like wine replaces exercise right?

    • @Crepitom
      @Crepitom 4 роки тому +1

      Ade S his next book, is called How not to age ;€

    • @wcraca5
      @wcraca5 4 роки тому

      @I like Potatoes it doesnt work if it's not vegan? haven't heard of a nation that's vegan, i guess i missed memo about French

  • @veronikazakharova4526
    @veronikazakharova4526 4 роки тому +3

    Big thanks, Mic. 💗 You are so good at breaking down complex studies. 👍👍

  • @MBison-im2qy
    @MBison-im2qy 4 роки тому +15

    2 seconds into video. "This is the best video ever!"

  • @PridedTomb55
    @PridedTomb55 4 роки тому +4

    I learned something from this video and that is eat plant foods,workout and do a bit of cardio

  • @jeanneamato8278
    @jeanneamato8278 4 роки тому +119

    You know what’s better than Metformin? Plant based eating.

    • @annala2956
      @annala2956 4 роки тому +5

      THIS!

    • @Kazuma-des
      @Kazuma-des 4 роки тому +6

      Ya man. Eat some beans & legumes to reduce sugar spikes instead.

    • @jeffk464
      @jeffk464 4 роки тому +7

      #1 cycling
      #2 cycling
      #3 cycling
      In that order

    • @brioche8123
      @brioche8123 4 роки тому +4

      Everyone wants to find the magic pill.

    • @ice1311
      @ice1311 4 роки тому +5

      Yeah i would take a banana over a pill any day

  • @justStardust940
    @justStardust940 4 роки тому +6

    It's amazing all the work you do behind the scenes for your videos. Thanks for all you do

  • @Test-eb9bj
    @Test-eb9bj 4 роки тому +4

    I wish I could like it everytime I watch it. Great job to condense those complex information in such a great video! I have watched all of Sinclairs talks and find his topic and findings fascinating. Will continue to follow his findings!

  • @jackiec8680
    @jackiec8680 4 роки тому +14

    "Where dem food that?" 💀
    Thanks Mic. I forever will see pikachu sleeping as AMPK lol

  • @CataNavarro
    @CataNavarro 4 роки тому +5

    Great video Mic, and agreat quote too! "The best strategy for animals (for increased longevity) is not to eat animals". I'll be citing you so much this week. Best regards ^^

  • @ronstanley9873
    @ronstanley9873 4 роки тому +2

    I am following David Sinclairs protocol I am 65, I have been watching you for a few years now,I went total vegan for one year I wanted it to work for me, but it killed my gut and I think gave me a slight case of IBS. now I fast 16 to 18 hours a day,calorie restrict and eat a more ketogenic diet,things are better for me, thats all I wanted to say,,and thanks for your videos I believe you help people..

    • @ganapatikitty
      @ganapatikitty 4 роки тому

      Thanks for sharing. I think being a vegan have me candida it was scary - once I eat meat my digestion gets good again.. I wish I could eat plant based but the meat does the trick I guess..

    • @Anthony-nx4vr
      @Anthony-nx4vr 4 роки тому

      @@ganapatikitty transition slowly. This will make you body be able to adjust properly.

    • @Anthony-nx4vr
      @Anthony-nx4vr 4 роки тому

      @@ganapatikitty I promise you it's only because your body is so used to your current way of eating. Anyone can eat plant based👍🏻😁 it's all about how you transition.

  • @veraromao1
    @veraromao1 4 роки тому +2

    I have diabetes type 2 and I decided not take insulin or pills for treatment like a 2 months ago I started this vegan diet got my diabetes decreased from 300 to 143 and it’s still working out and I am 54 in old and feel wonderful

  • @CheriLay
    @CheriLay 2 роки тому +1

    I listened to Sinclaire, he seems like a nice smart guy. I felt good that he said he eats predominantly plant based, at least he's not on some high protein or keto bullshit, which makes him at least more credible.
    Good points, Mike!
    David also said other interesting things that combat aging, like brown fat in your body, saunas

  • @bartacus2836
    @bartacus2836 4 роки тому +2

    I am still trying to stand up from the floor without leaning on something...

  • @NonDelusional74611
    @NonDelusional74611 4 роки тому +4

    7:37
    So I’ve got an ankle injury right now, and that standing up test proves I’m seconds from death

  • @litua13
    @litua13 4 роки тому +1

    The way you can research all of this is truly incredible!! Great video. Literally would never have come across some of the stuff you said if i wasnt subscribed to you. Thank you for that.

  • @deepakhiranandani6488
    @deepakhiranandani6488 4 роки тому +2

    😊😊😊 This video made me smile even more that the others. Thanks. Lots of witty amusing touches sprinkled right through, and of course your own smiles seen often too. 👍. Clearly a huge amount of research. Plenty for the viewer to digest. Or to try. Somehow I too would rather concentrate on and improve/correct if possible things like diet, exercise, sleep rather than chugging down supplements. Though I'm 62 to your 30. Yes exercise is my weak spot too... must do something about it. Anyhow, thanks again for an informative and very enjoyable video though it did keep my mind on its toes to keep up with all the knowledge.

  • @williamx0
    @williamx0 4 роки тому

    Your explanations and research are 10X better than almost all doctors (incl those on youtube) who just repeat the findings of his research and aren’t practical in application at all. Thank you for doing what you do.

  • @Minth431
    @Minth431 4 роки тому +4

    Yes! I was looking forward to this one! I’ll watch tonight. Thanks Mic!

  • @jaden.phillips
    @jaden.phillips 4 роки тому +1

    WOW. This was a wicked amount of research, absolutely awesome video!!!!!!!!!!!!!!!!!

  • @bridgetwatts2702
    @bridgetwatts2702 4 роки тому +2

    dying to know how you keep track of all your citations!

  • @gothichippielovechild3198
    @gothichippielovechild3198 4 роки тому +5

    🌱🌱🌱Hi Mic! Love your videos, thanks for great content! We’ll all make it to 100! 🌱🌱🌱

  • @waynegolding3184
    @waynegolding3184 4 роки тому +77

    I can't watch this right now but I've already like it because I know I will lol

  • @cclambie
    @cclambie 4 роки тому +2

    Thanks @micthevegan appreciate the research! Great video, as always.

  • @amiesmith4095
    @amiesmith4095 4 роки тому +2

    Fantastic video, thank you for making these complex issues understandable! So important.

  • @whitepeachtangerine7234
    @whitepeachtangerine7234 4 роки тому +2

    Thank you for always making this information digestible!!!! And for linking all studies that you reference!!! You put soooo much hard work into these videos and I hope you know how appreciative I am!!! 🌳🌿🌱

  • @woody3307
    @woody3307 4 роки тому +4

    As I recall the summary of the study on the Okinawan diet shown in your chart did conclude that they were very active physically and at that time were in a 200 calorie a day deficit according to their calculations. I model my own diet after this evolutionarily proven diet which jives with all the science we now have so I am familiar with the chart intimately, and my own personal observation has been that on some days when I drop to 1500 calories from their 1750 average I feel even better than if I grab the nuts and add extra 200 calories or more. And yet my body weight remains fairly consistent. The Okinawan diet is VERY efficient. Also, inexpensive at about $6 a day for me. Another critical factor in that same data brings up the notion that not all calories are created equal where the human body is concerned. The "O" chart indicates an incredibly low fat intake of 6 percent and 9 percent protein with about 85 percent carbs. Without the fat to gum up the works the mitochondria and other cell functions are extremely efficient. In addition, the Okinawans embraced the idea of eating til 8/10ths full which is suggestive of calorie restriction as a lifestyle. Add to this that they drank green tea all day which I find to give a pleasant anorexia. As far as eating disorders these longest living people enjoyed being hungry at times of the day as I have found by eating the way they did. This is not an eating disorder but simply observing a sensation that monk's have known for millennia which is that to really enjoy something you must experience some emptiness and enjoy that as well. Everything I have learned about the Okinawans leads me to believe they were physically active a good bit of the day although not running track or at the gym, they ate sparingly a diet of mostly sweet potatoes, rice and vegetables, they drank green tea and they lived on an island that was somewhat isolated and probably were exposed to very few damaging viral diseases that would have infected the cities in the mainland areas. Certainly the idea of drugs would have been unthinkable to these people as it should be to us all. We live in a medical matrix and few see true reality where health is concerned. Like chumps taking street drugs we are fooled too often by profiteering drug pushers and peddlers of misinformation.

    • @Felipe00162
      @Felipe00162 2 роки тому +2

      I am also restricting my feeding time and going to bed somewhat hungry. Amazingly, I am enjoying it! A lot! Thank you for your comment!

  • @roverdover4449
    @roverdover4449 3 роки тому

    I can find so many videos on both sides of these issues.
    But I trust Mic the Vegan and Dr. Gregor.
    Thank you for this.

  • @Rachel_2112
    @Rachel_2112 4 роки тому +8

    Talk about valter longo's longevity fasting-mimicking diet💚

    • @michaelmore
      @michaelmore 4 роки тому +2

      nutritionfacts.org/video/the-5-2-diet-and-the-fasting-mimicking-diet-put-to-the-test/

  • @Heidi_137
    @Heidi_137 4 роки тому +4

    That was an amazingly informative vid on anti-aging! Thanks!! Sometimes its far simpler than most think, eat WFPB and keep a good weight as well as sleep. Mental and emotional health is a big one too. All those supplements may not be assimilated to the body and it could end up being damaging more than good? I used to take well over 50 supplements a day while really serious about training weights but now with more studies I realize too much is not better.and presently take far less, the minimum, and feel great!

    • @markveen1373
      @markveen1373 4 роки тому +1

      Pretty much everything you can find in supplements, you will find in real foods. But with real foods you get the complete package, meaning better absorption and utilization. Also much cheaper.

  • @ozlemtuncel3032
    @ozlemtuncel3032 4 роки тому +2

    Thank you Mic for another great video and this awesome summary about these acronyms like mtor etc. Great content, much love from Toronto 🌱

  • @eelkeaptroot1393
    @eelkeaptroot1393 4 роки тому +1

    I had heard a lot about these different pathways cause I'd seen many interviews with doctor Longo. But I forgot what most of the acronyms stand for, so thanks for refreshing my mind.

  • @thebrunnerfamily192
    @thebrunnerfamily192 4 роки тому +2

    We appreciate all the well researched and organized videos Mic, keep up the good work 💪🌱🙏

  • @sapphire7004
    @sapphire7004 4 роки тому +4

    Awesome video! I love how much information you’ve shared

  • @astoria0777
    @astoria0777 3 роки тому +1

    this was really informative and digestible, thanks for the info. not plant based myself but i really appreciate your perspective and knowledge!

  • @WisconsinWanderer
    @WisconsinWanderer 4 роки тому +3

    Guess I’ll keep it simple, plant based and exercise. Oh I almost forgot no oil!! Thanks Mic☮️😎❤️

  • @dairy_fairy
    @dairy_fairy 4 роки тому +3

    I remember watching an interview that Tom aka the most tired looking man on earth that wants to live forever did with him. He gets compliments for looking younger than his age, but I’m sure he’s had cosmetic surgery done...

  • @jeanneamato8278
    @jeanneamato8278 4 роки тому +2

    You are one of the few I trust. keep it up

  • @simeoncarter3768
    @simeoncarter3768 4 роки тому +46

    But hold up Mic, Vegan Deterioration said vegans are aging terribly. She even has the heavily filtered pictures to prove it!

    • @gabrielgagne3850
      @gabrielgagne3850 4 роки тому +8

      I’ve seen a vegan that looked 38 and told me she was 60, it’s about crowding out the bad stuff with the good stuff, exercising and eating enough calories

    • @Fearzero
      @Fearzero 4 роки тому +7

      I will be 50 in 5 months. I date 30 year old women. Vegan almost 20 years. It has worked great for me, my junk works just as well as ever and no animals have to die.

    • @domenikschmitz334
      @domenikschmitz334 4 роки тому +2

      Why are you still "dating" at age 50?
      Don't you have kids?

    • @Fearzero
      @Fearzero 4 роки тому +21

      @@domenikschmitz334 Dom do you really want my life story? I am an anti-natalist. 8 billion people is enough.

    • @GarudaLegends
      @GarudaLegends 4 роки тому +3

      Look at freelee, vegan gains, mic the vegan, the vegan couple, unhealthy vegan, happy healthly(🤣🤣), vegans, ect... Never seen a single vegan who look younger than and old person.

  • @jabbathehutt1618
    @jabbathehutt1618 4 роки тому +10

    You’re SOOO funny 🤣🤣-that ENDING!!!

  • @rcic3706
    @rcic3706 3 роки тому +1

    Dear Mic, I just found your channel and I'm already deep in love with it.
    I would like to understand more about the sirtuins signalling pathway: activation, regulation, downstream effects. I was looking into it as linked with calorie restriction, but I just found a lot of reference to NAD and resveratrol. Could you address me to some material explaining this pathway and its correlation to CR?
    Thank you so much in advance,
    Roberto.

  • @Academic_G
    @Academic_G 4 роки тому

    Just an anecdote: I did a fasting-mimicking diet (FMD) for 5 days a while ago. I lost a bit of weight, but didn't lose any muscle. In fact, my first aerobic exercise after the FMD, was great. I took a vitamin supplement, of course. I will definitely keep trying it, since, although it was hard, the autophagy and loss of fat but increase in lean muscle mass, does feel good. I did do yoga and meditation and ate healthy, in-between.
    Love your vids and humor, Mic.
    Good work! I'll set some green tea and coffee now

  • @starsaligninthesky
    @starsaligninthesky 4 роки тому +19

    I have absolutely NO confidence in pharmaceutical drugs.

    • @charlesgraham5550
      @charlesgraham5550 4 роки тому +4

      Do you have any confidence in any non-'pharmaceutical' drugs? Come on, be honest...😄

    • @Joseph1NJ
      @Joseph1NJ 4 роки тому +3

      Great, let's bring back smallpox. Come on now, admit that was too broad a statement.

    • @AQWVegeto
      @AQWVegeto 4 роки тому +1

      @@charlesgraham5550 mushrooms and grass baby 😅

  • @verom1552
    @verom1552 4 роки тому +1

    You are amazing 🙏🏼💜 thank you this was awesome 👏 all my questions answered 🧘‍♀️

  • @nicolaybastos
    @nicolaybastos 4 роки тому +1

    Thank you for the rabbit hole research, this is why I love your videos!

  • @aSyMbolden
    @aSyMbolden 4 роки тому

    Good job to you man! Rich Roll shout out heck yeah!!

  • @bonniepoole1095
    @bonniepoole1095 2 місяці тому

    Great job condensing the research into understandable concepts.

  • @braveintofuture
    @braveintofuture 4 роки тому +1

    Great video! I just did the fasting mimicking diet for the first time and feel great

  • @ellistarceansa8182
    @ellistarceansa8182 4 роки тому +1

    I learned that I can't handle too many acronyms in one go ... NRM, NA, NR, NAD, etc.

  • @learningmoreabout
    @learningmoreabout Рік тому

    Amazing video I enjoyed your insights and the research love to join you on your next cruise

  • @andreawalker7138
    @andreawalker7138 4 роки тому +1

    AMPK, mTOR, NR, NMN?? I feel like I just watched the hardest episode of Sesame Street ever! LOL.
    But seriously, I'm going to have to watch that again and pay more attention this time.

  • @francescocastrillo
    @francescocastrillo 3 роки тому

    Oh my goodness you shoveled a lot in this video! Great job Mic!!

  • @jamessullenriot
    @jamessullenriot 4 роки тому

    Well I have watched so many Sinclair interviews over the past year, even ordered his book and am still reading it. I've also heard Dr Rhonda Patrick talk about the same topics. Nothing against them two, but your summary of all of these topics is so much clearer. Now it may help that you don't have Joe Rogan interrupting and trying to steer the convo, but still, this is such a clean presentation.

  • @brioche8123
    @brioche8123 4 роки тому

    I love HIIT. I discovered it a few years ago in high school. Can’t live without now. I had no idea about It’s connection to anti aging

  • @456mjb
    @456mjb 4 роки тому

    Excellent points about the downsides of fasting, and great explanations of processes I vaguely understood before!

  • @perlaserrano1791
    @perlaserrano1791 4 роки тому

    Thank you for taking your time to make this video! :) Very useful!

  • @tyras_heartlocker
    @tyras_heartlocker 4 роки тому +1

    Love that you’re always objective and entertaining!!

  • @michaelholliday6216
    @michaelholliday6216 4 роки тому +1

    Thank you mike! You’ve done me so many favors. I love all your videos

  • @angelagarcia7093
    @angelagarcia7093 3 роки тому

    I'm still on the younger side, so I'm going to wait a few days before I decide to try longevity supplements. For now, just focusing on foods

  • @anulfolantigua6291
    @anulfolantigua6291 4 роки тому +1

    Wao Franklin this has been the most interesting video I had ever seen in a while I just wanna learn more about this increase on longevity stuff

  • @kiaranjay5153
    @kiaranjay5153 4 роки тому +6

    I'd be interested in your thoughts on Valter Longo's works with the fasting mimicking diet, unless you've covered it before..

    • @michaelmore
      @michaelmore 4 роки тому +3

      nutritionfacts.org/video/the-5-2-diet-and-the-fasting-mimicking-diet-put-to-the-test/

    • @kiaranjay5153
      @kiaranjay5153 4 роки тому +3

      @@michaelmore Thanks for the link. Can't go wrong with Dr Greger!

  • @TCMcGowan
    @TCMcGowan 4 роки тому +1

    Thanks for doing that - its a ton of research!

  • @JD-xh6cy
    @JD-xh6cy Рік тому

    Thank you for this great video! I appreciate the effort you put into the research and that you tell us the about the quality of the studies.

  • @AngelaKayAustin
    @AngelaKayAustin 4 роки тому

    For those of us over 40, thanks for the research! This was interesting. I think I'll stick with working out as well.

  • @Kristers_K
    @Kristers_K 4 роки тому +1

    Living forever? Hard to say, on one hand it would be fascinating to see the world around you change, grow and evolve...or fall, but on the other hand, people you get close to, people you know would die time after time, pain and suffering, and in general the toll it would take on one's psychology as ages go by. It would be tough, and there would come a point where you are just tired of life and would long for the peace of death. In a way, death gives life meaning, the limited time you have, but if you never die then eventually all becomes meaningless.

  • @lainisos
    @lainisos 4 роки тому

    I love how excited you get when you talk about your research lol. Thanks so much for another great video!

  • @andrewpennington2251
    @andrewpennington2251 4 роки тому +2

    Love your work. Thank you so much.

  • @renee3384
    @renee3384 4 роки тому +1

    thank you for the effort you put into your videos!

  • @SEACRUZNY
    @SEACRUZNY 4 роки тому +3

    Forever Young 👁🙏👁

  • @mskittygemma
    @mskittygemma 4 роки тому

    "disordered eating does not help with your life span unfortunately"
    *Flash backs to my ED in Late 2017 to Early 2018*

  • @Firebuck
    @Firebuck 4 роки тому

    @Mic the Vegan Dr Gregor has a chapter in How Not to Diet called "Amping AMPK". (Not only does AMPK activation correlate with better mortality outcomes in people, it also appears to contribute to visceral fat loss.) Gregor talks about nicotine from veggies (pepper, tomatoes and other nightshades), acetic acid (from SCFA produced by gut flora -- go fiber! -- or vinegar in the diet), and barberries as some of the ways to amp AMPK. If you want to follow your current research rabbit hole even farther the book has 5000 references (!) listed for free on the nutrition facts site. The citations for the Amping AMPK chapter are 2564 - 2680.

  • @thedancingveganatheist6310
    @thedancingveganatheist6310 4 роки тому

    A monthly or weekly 24-hour fast is perfectly reasonable. It can be supplemented with increased caloric intake (during non-fasting times) for the very thin or very old.

  • @gigio2376
    @gigio2376 4 роки тому +1

    This talk of demonizing IGF 1 doesn't make sense since exercise also raises serum IGF 1 levels, not just eating animal protein

  • @sarahbridgemancomedy
    @sarahbridgemancomedy 4 роки тому +2

    Bravo, I don't know how you manage to make these studies digestible (pun intended) but you do, nice one 😀👍👏👏👏

  • @juz5zzz
    @juz5zzz 4 роки тому

    Great Vid as always Mic, I will definitely need to watch this one again as there is much to take in. Interesting about the height/ longevity connection.

  • @JustJulia-qt9nh
    @JustJulia-qt9nh Рік тому

    I love this! Great work on this video and wading through all the technical jargon. 😆

  • @jennymorgan6810
    @jennymorgan6810 4 роки тому +1

    Bravo, another masterpiece!! Love you

  • @DIYDSP
    @DIYDSP 4 роки тому +1

    mic's like me: got into veganism for the animals, then got super nerdy abt the health benefits!