Alpha Lipoic Acid | The Most Promising Compound for Inflammation and Insulin Resistance
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- Опубліковано 15 тра 2024
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References
www.tandfonline.com/doi/epdf/...
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pubmed.ncbi.nlm.nih.gov/10926...
www.ncbi.nlm.nih.gov/pmc/arti...
www.liebertpub.com/doi/10.108...
www.ncbi.nlm.nih.gov/pmc/arti...
pubmed.ncbi.nlm.nih.gov/25245...
www.ncbi.nlm.nih.gov/pmc/arti...
Timestamps ⏱
0:00 - Intro
2:00 - 30% Off Your First Order AND a Free Gift Worth up to $60
2:42 - Reducing Inflammation
4:37 - Prior to Exercise
5:45 - Diabetic Neuropathy & Circulation
6:28 - Who is ALA for?
8:18 - When & How to Take
With your hundreds of things that you have told us to take, it would be a really good video to pair it all down and give us your top 25 or something like that!
Its best to cycle your supplements.
"Take it on an empty stomach." Again? There are just not enough hours in a day to take everything you need on an empty stomach 🤪
Good point!
That's my main issue while taking herbs, supplements, etc.
Haha, very well said, so true
You should only be eating 1-2 meals a day
Just do it when you wake up...
If you are on HYPO-Thyroid Meds, ALA will suppress T4 to T3 conversion. That is a problem.
Wow, didn't know that, thanks. But isn't it true for everyone (but obviously more of a risk of hypothyroid people)?
Show the evidence, please.
Well, why the fucccccc do you have thyroid probs. Fix your damn diet lol
Alpha Lipoic Acid is has tremendous benefits for your liver as well. It in fact has been known to actually aid in liver regeneration. However, R-type has much greater bioavailability than the s-type, which is half natural, have synthetic. The reason that s-type is made is because ALA must be stabilized in order to provide any benefit, and can actually be somewhat detrimental if it is not, in supplement form. If you do go with r-type, make sure that it is stabilized, usually with sodium atoms. S-type works as well, but is less potent
Name a good R brand please, thanks.
Thomas, you should've discussed R-Alpha Lipoic Acid vs. S-Alpha Lipoic Acid.
Correct! R is the better one
natural version of ALA, R-ALA more fast to absorb than non R-ALA and have controversy dosage for consumtion if you have neuropatic problem
You’d really think he would have mentioned it
APA helped a lot with my Chronic Fatigue Syndrome! I take it everyday!
I do reduced form: R-ALA, with benfotiamine, and L-Citroline. Tom does superb presentations!
Great news. Thanks! I am already taking R-ALA.
But I also follow an anti-inflammatory diet as much as possible to help with my arthritis flare-ups.
Thank you, Thomas, as always, very helpful video as I never hear much about what helps with inflammation and insulin resistance which most people have excess of
ALP Alpha Lipoic Acid
This was the best timing as I'm having an inflammation and insulin flare up as a PCOS sufferer.
Whats PCOS?
Polycystic ovarian syndrome.
Thanks!
I usually have high inflammation as I have endometriosis so I take it to help out with the inflammation in general. I do take R-ALA
Save money by waiting for the "Why-I've-Changed-My-Mind-On-ALA" video.
Thats why your a loser in life lol
I have been dealing with plantar fascitis for a year and a half. Started taking this and after 2 weeks it is gone! Still good for over a month now. Thankful!!
Really?? Thats exciting. Ive been dealing with it myself. Im doing the excersises for it and it will not go away. Imy going to try ALA. How much have you been taking if you dont mind??
@@taoster3638 I did a lot of things with no success. I take B R O N S O N brand, 600 mg., one twice a day. Its like a miracle. Good luck.
Why would you hide the name of it lmao I get why the youtuber does it but lol...
Its ALA @@bjornlindgren1774
Change your shoes. Had planters for entire year and it was brutal. Stopped wearing my dress shoes that i wore everyday and got new insoles and it all went away. Foot doctors could not do anything for me until I changed all my shoes out with new arched insoles. Haven’t had a problem for years.
R-Alpha Lipoic Acid is the best type I've read and heard.
I just now ordered those nut butters on Thrive!! Very excited to try them
Could you please Tell me the products Name? I do Not find a Link
Helped my senior dog recover from a spinal issue and regain hind leg use.
Have been taking the Solgar ALA for quite some time. It is one of the builder blocks of glutathione.
Same here, I have been using it on and off for 4 years for diabetic neuropathy!
Kind and brand please.
There has also been many studies on Glisodin in reducing free radicals. It comes from a Mellon wheat gliadin that increases natural endodogenoes like catalyze. I have good results also good for sunburn protection 😊
It's also used for H.M chelation.
I started taking because it helps with nerve pain and nerve damage. Then I saw it can lower blood pressure as well and I have that. So it is great. If it has even more benefits I'm very into it
Please do a Video on Zeolit ❤
Had neuropathy in feet for years while battling diabetes. Managed to get it under control with nutrition and exercise but take ALA daily as it has significantly reduced the sharp and burning pain. In fact over time it is nearly gone. But as a fitness product, probably shortchanges the possible gains.
How much do you take a day? What brand? And are you taking R-Alpha Lipoic Acid or S-Alpha Lipoic Acid?
Yeah wouldnt you want inflammation to recover after workout?
YES!! ALSO WITH ME TOO!
Been taking it since 2004 along with ALC....
Oh man. Wish I knew this 3 days ago. My workout put so stress on me, thought I was getting the flu for 3 days.
Hey Thomas, love your videos - been watching since I started my journey back in 2015. Could you slow down a bit when talking dosages? I've noticed lately it's often really quick and easy to miss, maybe highlight side effects(if any) to look out for? Wish ya the best
Edit: this video is actually solid though lol
Hi, if you go to the Settings icon at the Top Right of the video you can choose a lower Playback Speed any time you need to double check something!
I had heard that only if you have chronic health issues should a person take it. It really seems to help neuropathy and diabetes issues for certain.
LOL
I have been taking ALA for years for neuropathy. You do not have to take it on an empty stomach. BTW Love the macadamia nut butter.
do you still think boiled oysters in water are good to eat frequently? Like from Otter Kingdom? I only heard because I havent heard you mention oysters in a while. Love the videos
Alpha lipoic acid is the second enzyme cofactor needed in the dehydrogenase enzyme complexes such as pyruvate dehydrogenase, a key part of metabolism. Right after the first which is thiamine.
I take Na-R-ALA, 2×300mg
I've taken the racemic form, the powder burns in the throat. If you try it, use the stabilized sodium r-ALA.
My doctor told me to take this for my neuropathy i had stopped taking it for a bit and my neuropathy was bad again so it does work and i just started caster oil on feet that helps too
Omg, macadamia nut butter? I order from Thrive Market twice per month. I didn’t know they carry macadamia nut butter. I’m getting some today for sure. 🤤
I also make my own nut butter, if you are into that
How about GliSODin?
Any suggestions on the brand of this supplement?
I've read it also helps with fatty liver
Sounds like ALA works for intermittent faster and daily exercisers
During the early 2000s,musclethech used to add ALA to their creatine supp and even Dymatize added the ALA pills with their creatine supp. Wonder why?
Been taking Alpha Lipoic Acid for years.
Do yu have inflammation?
@jogilliland8364 everyone dose bc ur suppose to
shouldn't we take SUPPLEMENTS NOT PERMANENTLY?
@@bladadupa8774 You can't take it permanently.
Are you a health superchad?
I got big on APA about 9 months ago. I was taking about 1800mg daily for about 6-8 months. At about the 7-8 month mark I started getting weird sensations in my peripheral nerves. I played around with process of elimination for a while trying to rule out what it could be. I stopped ALA cold turkey and it went away. I hope I can start taking it again as I felt it was beneficial but I can’t even take 200mg now with causing some weird sensations in my fingers and toes.
Hey Thomas, I joined Thrive recently, thanks to you, and I am enjoying your nut butters. Thrive is helping me improve my eating and I am feeling a little better (after just a few weeks). Thanks for your informative but accessible videos. Trying to change my life (turn 55 soon), and it helps to have modern information that is science based and continually updated as new research comes out. 🤘🏻
I'll be 55 on June 30! Happy Birthday to us!
Your telling me with everything you do, Mediterranean diet , 300 sups you still get inflamed 🤔
Initially, I was erroneously using *S-ALA (S-Alpha Lipoic Acid)* as opposed to the more bioavailable *R-ALA (R-Alpha Lipoic Acid)*
Natrol Alpha Lipoic Acid (ALA) Time Release Tablets - 600mg. Is this a good ALA?
If you take it right after a workout won’t the lower ph of your blood from lactic acid affect the absorption?
Ok, so how much do you recommend and can I just take it first thing in the morning instead of trying to juggle taking this on an empty stomach and then waiting more time to eat dinner? I generally fast through to lunch and try to eat about 3 hours before heading out for my workout, but taking this first thing in the morning, maybe with my coffee, keeps me in an acidic stomach and no food having environment.
THANK YOU 🙏 I love you too death,,,,,,,,,and I know you want to explain things very detailed,,so I appreciate you finding a way to “tightening things up and getting to the point….. I’ve always enjoyed your videos…so I had to skip so much and go back later if I remember…..now I have time to finish….i truly appreciate you & the info…thanks for getting to the point faster and shortening things…Fan for life❤
Lol get a life
Doesn't an anti-inflammatory effect blunt hypertrophy?
When i took it.. my arm and the space between the neck and shoulder started to hurt.. i think those are nerves that hurt. Also i had a slight headache too..... this doesnt mean its bad, it might just mean it does stuff.... mby i need something else that supports those processes.... idk
Is this stuff safe for people w sarcophagy of aging w autoimmune disease? Why not speak about the twotypes and how only R is effective and the other form negates the active one%?
It gives me brutal heartburn with or without food…
Drink a ton of water with it
i have a 500 mg dose which does that. At 100 mg I am fine, so get a weaker version.
You want the "R" type.
Is red meat specifically beef?
Right but are the stength gains the same once inflammation is lower? Isn't oxidative stress what makes mitochondria improve?
Good point. So maybe do not take for a couple hours after workout? As with a cold plunge, anti- inflammatories or antioxidants. Just speculating here.
A big problem, though, is that NA R ALA is more expensive than steriods!!!
I don’t take it because I’m a very intense sitter inner…
What about chronic inflammation? Can ALA help this?
Yes, paired with an anti inflammatory diet, adequate sunlight exposure, grounding and adequate sleep.
Carnivore diet can rectify that problem.
Is this the same as b1?
If you take ALA on an empty stomach, how long do you have to wait with eating after you toke ALA?
What about those with amalgam fillings?
Foods high in ALA:
Red meats
Organ meats
Broccoli
Spinach
Tomato
But I get it. Thomas means taking in more than from food.
Flax seed oil should have like 50 % of ALA in it. I combine it with EVOO for my salad daily, like 2/3 EVOO and 1/3 flax seed oil...
@@andrejpolak8946I believe you're referring to alpha linolenic acid in flaxseed oil.
Wait what is the compound?
ALA 4 life
It's brilliant for skin health and I'm sure for tons of issues, but it gives me low mood 😢
I almost always get crazy heartburn whenever I take ALA without food and even sometimes when I take with a meal. Recommendations how to mitigate this is appreciated!
weaker dose. I never had a problem until I got 500mg capsules.
Does anyone else experience constipation issues after taking ALA?
I will tell you what the compound is 2 seconds before the sponsor sale
Who all ran to amazon? Hahahah
Skip Amazon. The stuff isn’t tested to even contain traceable amounts of what you’re looking for. Go straight to nootropics depot and get the real things that doesn’t waste your hard earned money
The most educated scientists in the world say ALA's two enantiomeric forms, called S and R enantiomers cancel each other out. But TD is catching up. TD is only 25 years behind the most advanced science. :)~
Who all?!?🤌🏻🙄
@@DebbieTDPAre you aware you could research ALA on line and find this information?
@@knowledgeishalfthebattle = Full of 💩
Should we take ALA or R-ALA or S-ALA, which one is the best ??
R-ALA. It is the biologically active form of the molecule.
@@davidmontoute2074thanks
It sounds like this might be one of those compounds that ends up blocking the good effects of exercise. The whole point of exercise, especially vigorous exercise, is to create inflammation that your body fixes up, regulating your endogenous antioxidant mechanisms. At least as I understand it.
We shouldn’t be interested in primarily how it effects inflammatory markers, but we should be more interested in things downstream of that like: does it improve response to exercise or weaken response to exercise.
I take it and I'm jacked so I don't think it blunts hypertrophy or endurance training. Not enough to make any noticeable difference. Idk maybe I'd be more jacked if I didn't take it but for me the benefits outweigh that hypothesis
I was thinking the same thing.
I kinda thought so,if we don’t want soreness effects of High intensity exercise, kinda like why exercise, just sit our ass and save money and not pill pill pill SOLUTIONS. WHEN SORE AFTER EXERCISE YOUR BODY WANTS YOU TO REST IT, guess what that’s how our bones get strong. Osteoblast osteoclast theory pe se. Your muscle will heal.
I was wondering about that too. Is it going to prevent muscle growth?
@@bigbadwolfe7849how many mg a day?
So you wouldnt recommend taking any antioxidants daily ?!
Because im taking a bunch😅
If you have heavy metals you should not take ALA bc it displaces them.
What is a worker-outer lol
The Macadamia nut butter is terrible.
Hopefully somebody in the comments can answer me I don’t think he will see this but I’ve been doing keto for about three months now and intimate fasting. I normally do a 23 hour fast besides drinking a coffee in between the day with heavy cream. However, I developed a very low appetite, but I’m starting to worry that I’m not eating enough protein to maintain or build muscle cause I could only consume about 900 to 1200 cal per day. Those calories are all healthy, fat and protein. I am 6 foot tall and way 278 and I am active in boxing.
I eat a lot of red meat and that is one of the foods that naturally has ALA. What the recommended daily amount one should take OR am I getting enough while doing a carnivore diet?
Nobody knows. The good thing is your eating the right foods that contain not only ALA but so many other important nutrients.
That depends on your health issues. If you have neuropathy, then Carnivore's great but alone probably won't repair those nerves. R-Alpha Lipoic Acid and Benfotiamine supplementation will.
Good point about the RED MEAT!
If you're taking ALA to control blood sugar shouldn't it be taken daily?
Yes, but not indefinitely. The long-term way to control blood sugar is through Carnivore or Keto, as well as daily IF and periodic PF.
Thanks for sharing 😊
@@Cosmo-Kramer Thanks, I'm familiar with everything except PF, what is that. I may know🤷🏻
@@mybabybookpage Sure. Prolonged Fasting. IF is fasting a certain number of hours per day, and PF is fasting multiple days in a row.
I used to take it too, but stopped.
It would be really helpful to know why you stopped taking it? What did it do to you and how did you take it?
Is it “worker outer” or “work outer”?
Workener whats of the outs
I wonder if Olympic athletes / big time athletes are already up on this.
They tend to supplement with BALCO.
Ask Putin.
Yes I used to take that as well for a while but the acid it created in my stomach was out of this world. Wasn’t able to keep it up unfortunately
Take it with breakfast or lunch. Not on an empty stomach 😅 even if Thomas says the contrary 😊
@@DebbieTDP thanks Debbie, let me try that
@@redzebra6688 I've been on and off ALA for years, I used this trick at the beginning. Now I can take it without problems without food. 👍🏻
Let me know 🙌🏻
Tinnitus on keto ?
I get acid reflux on empty stomach
Just be careful if you're not low carb because Alpha Lipoic Acid can effect low blood sugar. 🥰
I literally tripped while walking because dude said “worker-outer”.
English is not my mother tongue and I noticed that. He must believe it's work out instead of workout ie. worker outer instead of workouter. Or maybe he just needs to be special, because he often uses witty phrases.
Same lol.
Authors and video makers often "stretch" language and use odd combinations and spelling in order to be creative or emphatic or to gain reader attention.
It's definitely more challenging to those whose first language is not English. I'm certain this is done in other languages as well.
@@igorpotocnik7231 "Exerciser" works as well lmao
Does the type of ALA have any effect on bioavailability? R - ALA. versus S - ALA.
You want R-ALA.
If there's one thing american public schools taught it is that the mitochondria is the powerhouse of the cell.
👍
I take it every day. The best for anti aging. Youth in a bottle. I take it to look better, not for inflamation. I'm 59 and I look 35 because of the antioxidant effect. I take it during my 12 hour fast, which is the best kind. Seems like you're still missing the point of taking it.
What brand?price?
Sadly I’ve gone from 12 stone to 15 buy taking all these Vitamins..😂😂😂😂
But inflammation builds muscle.
THERE ARE DIFFERENT TYPES OF BODY INFLAMMATIONS AND CAUSES. MUSCLES WILL GROW FROM IT'S SPECIFIC WAYS OF NATURAL REBUILD PROVIDED WE HAVE STIMULATED GROWTH AND RECUPERATION. LIKE MUSCLE STRESS AND LIFE WORRIES AKA BRAIN STRESS ARE DIFFERENT. SICK, INFLAMED PEOPLE NOT HEALTHY PEOPLE ARE NOT GOING TO HAVE A MUSCLE BUILDING ADVANTAGE OVER A FIT, HEALTHY, ATHLETIC PERSON PERIOD.
Imagine that, Thomas pushing another product 😅
With older adults having more inflammation, wouldn't it make sense they would be a candidate too?
Worker outer...
I thought the current trend in anti-aging is that too many antioxidants are bad for us.
The studies you refer to all seem to measure biochemical endpoints rather than quality or duration of life endpoints. So I'm still a bit cautious with respect to high-dose ALA.
My man……if I took everything that you told me to take I would need to own a supplement store and eat only those supplements because I wouldn’t have money for food!!!!
Sales pitch informercial channel
New studies show… Worrying about all these supplements to maximize one’s performance is twice as detrimental as any benefit from the supplement itself. Kidding, but seriously.. Stress less, Eat smart, train hard & prioritize rest.
K.I.S.S folks…