The End of Ozempic - What Shocking Research is Now Showing (Dr. Peter Attia & Dr. Nadolsky Opinions)
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- Опубліковано 28 тра 2024
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Is This the End of Ozempic?
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Timestamps ⏱
0:00 - Intro
1:12 - Ozempic for Weight Loss & Reducing Glucose Levels
2:32 - Nausea
2:59 - Muscle Loss
4:11 - Dr. Peter Attia & Dr. Spencer Nadolsky's Views on Ozempic
5:47 - The Good News (GLP-1 & Muscle Growth)
6:49 - Preventing Muscle Wasting on Ozempic
7:50 - Urolithin A
9:03 - 10% Off Timeline Nutrition MitoPure
10:05 - Taurine
10:41 - Essential Amino Acids (EAAs)
11:18 - Creatine
11:57 - Protein is Crucial - How Much to Consume
12:41 - Recap
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your understanding on the insulin secretion from GLP-1 is wrong - which is very common. the release of insulin gets faster when the beta cell GLP-1 receptors get triggered. but not more insulin. it is less insulin. there studies regarding this and the show a very nice graph. that shows a higher insulin spike but it was way shorter. and the AUC (area under the curve) showed that the total amount of insulin was lower over a longer period. this is part of the weight loss.
with more total insulin you get fatter and not slimmer!
@@stefanweilhartner4415just
😊
@@stefanweilhartner4415ah very interesting. Thanks for enlightening!
Wow Thomas is looking really old in his face these days, not as bad as Paul Saladino but still aging quicker than his actual age. Maybe he should change up his diet (more fate needed), put less strain on his body with workouts and stop fasting.
I've been on mounjaro for 20 months because my physician called me about my blood results, indicating I would have a heart attack or stroke in 6 months without lifestyle changes. My physician decided to put me on mounjaro. My weight was 480 lbs with A1C of 6.9 and a body fat percentage of 48.7%. Today, I weigh 299 lbs with A1C of 5.1 with a body fat percentage of 26.0%. I'm off my high blood pressure medication and no more joint pain. I use mounjaro with strength training 5 times a week with a daily 45-minute walk. I feel so blessed to have my health back. I feel amazing.
That’s great. A lot of these people won’t understand what you were experiencing and will call you lazy. Sometimes we just need the little extra push and as much help as We can get. Yes these medications may have side effects that we don’t even know about. But in your case you had to make a choice between a death diagnosis, and a medication that could help you get started in the right path. I believe you made the right choice. My only advise to you is to use this medication as a tool to teach you how to eat correctly and start exercising slowly till your life is completely changed and you no longer need any medication. The point of this medication should be a help to transform your habits.
Should try just eating meat for a month. It might sound crazy but that's how I lost 30kg and turned my life around
@@Jason31256I know a vegan who did the same thing!
Very happy for you!
Yea good luck with the long term side effects ….
“If you have taken Ozempic you may be entitled to compensation” coming soon
You, or your deceased loved one, took Ozempic most likely.
That’s already on tv. I work in healthcare and those ads run constantly. It’s for people who experienced organ system damage due to Ozempic.
Yep
👍
no kidding
I cut out junk food, I eat whole food, and as minimally processed food as I can. My clothes fit again, and my pants are actually falling off. No Ozempic.
same here
💯
Five years ago I commuted to work, sat most of the day, ate out nearly every day, and ended up hitting the heaviest weight I've ever been (215 lbs, 5'9"). I started to lose it before the pandemic hit, but when it did I found myself working from home, where I've been ever since. I started preparing my own meals, working out regularly, walking frequently, and jogging. Lost about 10 lbs a year and now am about the same weight I graduated from high school at (several decades ago), and feel like I'm 30. Basically the cure, or the fix, is to retire from our sick society and take control of your life. Unfortunately the number of people who want to do this is fairly small, and the number who can is even smaller. Now that a combo meal at McDonalds is about $20, a lot more people may be pushed in this direction. They may find it burdensome, but it will be the best thing that ever happened to them, as the pandemic was to me.
@@davidkusner5637 congrats!! I was them. There was something always preventing me from just doing it. I took a week made my diet plan, which is really a lifestyle change not a diet and started losing 10 pounds a month. I eat a lot of proteins, spoonful of vegetables with each meal, eggs, half of avocado, nuts, etc. I recommend people take their time and prepare the change. You have to follow certain eating habits on Ozempic anyway. Gradually introduced intermittent fasting and walking. Nothing over the top But it made a big difference in my life. Good luck everyone.
I need to do this again it feels so good to not me suffering from inflammation
My ex was complaining how better quality food was so expensive and wants to go on ozempic for like $1350 a month. Seems like a pretty common thought process.
He would be better off fasting.
Wow I didn’t know it was that much.
Yo this hit hard and is so true! We always strive for the easier way, while deviating from the more feasible way avenue.
“My ex”
Good decision 👍
You can get it way cheaper than that. I'm talking less than $120 per month
I have binge eating disorder and Ozempic has quieted the “food noise” from my brain. I was 414 pounds. I’m down to 364 pounds (losing about 5 pounds per month). I’m looking forward to being able to walk unassisted again!!! And yes, I do work out with a trainer.
I started tirzepitide 15 months ago and lost nearly 200 lbs in the first 10 months. I know that i lost a ton of muscle mass even with resistance training added in. However, I would say for Me, i wont speak for anyone else, getting the weight off quickly, being able to move more freely and because of that, add in more activity was more important to me than the possibility of losing muscle mass. Maybe its short sighted, but, I think me at 180 lbs going to the gym training to build muscle, is a lot more healthy than a1c through the roof at almost 400lbs, still struggling to do things a "more natural way." I doubt i would have ever done it after a decade plus of trying alternatives.
Awesome you are making so much progress. My wife says it helps her not to think about food so much. I think we are all so different and if it helps people get started and see some quick progress they will stick with it.
@righthalfthetime-do4nt thanks! I can definitely agree with your wife about the not thinking about food part. It's been a game changer for me. Everyone has different health goals and journeys, but I will say watching Thomas's videos help keep us all pointed in the right direction, which is just a better/ more healthy version of ourselves.
@@RollingRocke"Everyone has different health goals and journeys," exactly, well said.
I used to be obese and although I didn't take Ozempic, the diet that worked for me _worked for me_ and we're all different. Congratulations on your weight loss, isn't it a great feeling!
Come back in 2 years to tell us how your life is then.
Dropping muscle mass won’t kill you. Obesity will. Once you can move better you can gain appropriate muscle mass back. Consider all the social influencers promoting calorie restriction for longevity. They are not worried about above average muscle mass. It’s all about nutrition and movement.
How about the REAL QUESTION 👀.
The effect on CARDIAC ❤️ MUSCLE 👀 ???
Logically its lost at the same rate, take Ozemoic with Oxandralone to save muscle...Including you heart
Great question!
The new discovery is OZEMPIC reduces heart issues but 25%.. so…
You might want to do your research because GLP-1 agoists are extremely Cardiac-Protective! I am Type-2 Diabetic and my doctor prescribed me Mounjaro last fall. Aside from all the improvements I have experienced specifically regarding diabetes before I had even lost ten pounds my blood pressure had gone from 165/90 down to 123/78 which was absolutely stunning.
Years ago I had a Dr that put me on a cocktail of off label meds for weight loss. I was skinny for the first time in my adult life. I felt like crap though. And when I stopped them, I gained most of the weight back. This was my personal experiment on why there's no magic pill for me. I needed lasting changes to my lifestyle, healthier eating, more movement & therapy for my stress in an abusive relationship.
Everyone is different & I can see the benefits for someone who's so overweight that it's life threatening. As with any medication, each person most weight the pros & cons in their individual situation. These sorts of videos give more information on making the decision that's right for you. For me, it's a no. I'd never use anything like this again.
N=1 lost 125lbs to my target weight on Mounjaro. Maintaining and even lost 5lbs more while off for over six months. Couldn’t have done it without Mounjaro!! Best thing I ever did. Allowed me to change my diet, exercise and weight training when nothing else worked!!
As a practicing endocrinologist, I am a doctor and prescribe these medication’s frequently to make my patients more metabolically healthy. I emphasize all the points that you discussed, and it does help them preserve muscle mass. The problem is prescribing physicians don’t discuss the importance of nutrition and resistance training, when using these medication.
If they had focused on nutrition and resistance training initially, they would not need these medications. But you can't get some people off the couch.
What was the long term side effects? Or don’t they talk about it in medical literature? Don’t trust them after COV-VID lies.
@angelaadams3625 that is not true and very ignorant of you.
Had a whole lot to do with the fact that drs don't get hardly any nutritional training in medical school and because they ONLY know how to use meds to treat people, they just ASSUME they're being lazy, when they're just given wrong dietary advise.
@@steelergr1975Agreed a lot of weight gain is tied to genetics and aging also obese people will burn less resting calories then those with normal BMI after exercise making it less efficient, no to mention post exercise hunger.
I lost 22% of my total body mass, 59lbs in 15month. 32% body fat down to 18%… No Semaglutide or any other weight loss supps except caffeine. I just ate properly, 3x week full body strength training, 10k steps a day minimum and I followed most of the advice Thomas gives daily. I also watched his content multiple times a day to stay motivated. I’m at the 2yr mark now, weight is still off and stronger than ever. LMNT, taurine, green tea, 200g protein a day and also blueberries when I have a sweet tooth are daily mandatories too. Thomas, keep up the great work and content! You’ve helped change my life and saved my career.
well done. you're a good role model for others in your life hopefully.
You were dumb enough to get fat dont brag that you lost it.
Everybody loses muscle if you are on a strict diet. I lost a ton of muscle doing super strict keto.
It depends on how you diet. Rapid weight loss means you will typically retain less muscle. Slow controlled weight loss who is hitting their macros while on a slight caloric deficit will retain far more muscle.
On Mounjaro for what it was designed for Genetic insulin resistance and type two diabetes. Don’t have a lot of weight to lose. Only lost 15 lbs in 8 months. Could stand to lose about 15 more, but totally okay if I don’t. Keto diet, but modified with higher protein and also practice IF. No nausea, no vomiting, no negative side effects so far. A1C is 5.1. I feel better than I have felt in years.
Mounjaro is the best one. Least side effects. Im on it now and only issue I have is acid reflux the first few days of the shot. A1C is down to 4.7 and Ive lost 36 pounds.
I was prescribed this by an endocrinologist before I’d ever heard the name of it. I lost 15kg. Yes, I had nausea, but I have no regrets.
I’m curious. It seems many people gain the weight back when they quit. Were you able to avoid that? If so, that’s awesome.
@@Sacarat no, didn’t gain it back. It gave me the kickstart I needed and I didn’t get Ozempic face. One of the best side effects was the aversion to alcohol.
Good for you the only thing I want to add is that it seems like the reason why people lose so much weight is because even a binger like me could not eat if I wanted to 🤢🤮. I guess all I’m trying to say is it’s still calorie restriction it’s just easier to restrict when you can’t keep food down or want to eat!
@@ryanlewandowsky2077 I think it works at a more scientific level to do with controlling glucose levels and glucose spikes. I have never been a big eater or eaten poorly. I am a woman and in my forties so there are always hormonal challenges. What actually piled my weight on was a severe burn out which was actually a physical burnout not a mental one. It landed me with crippling anxiety which is never bad in my life. It all hit me in a week. Then my doctor over prescribed me with anxiety meds. 40mg which was double what I should have been on. At the time I had no clue. If he had me on 100mg I would have done what he said. Then I broke my ankle… this wasn’t a case over uncontrolled eating. But I do get your drift this is the case for some. Reducing alcohol was probably a huge factor because it prevents fat loss. Though I wasn’t drinking huge amounts it was regular red wine with my meal kind of thing. I have an added complication which I’ve only just sealed with medically. It’s called LIPOEDEMA. Most doctors, at least in Australia don’t know what this condition is. It affects 1 in 10 women. It’s genetic. I am not going to explain this but for any women who read this and have fat they cannot lose on their legs, hips and butts, including arms eventually (there are more factors) look up this condition. It’s taken me 40 years of wondering what was wrong with me for no matter how hard I worked out or healthy I ate I could not lose this weight. This is scientific so please do your research. Perhaps your spouse struggles this way. Honestly, knowing what this condition is, is a game changer. I will say it again LIPOEDEMA.
I have no problems on Oz. No side affects. Lose it slowly, high protein and exercise. I started slowly.. better than all the health issues with obesity. I like it.
I've been on Trulicity for a year. Lost 40lbs and my A1c dropped from 8.4 to 5.5. I used to get nausea, but eventually figured out that it was all about what I was eating. Eating too much and eating too much carb heavy food makes me nauseous to the point where I would have to throw up to feel better.
Changed to a high protein, fiber diet and the nausea went away. Started actually weighing and tracking my food. I can still indulge in carbs on special days like holidays without getting sick. I wouldn't say I have ''Ozempic Face." But my face is for sure thinner from the weight loss.
Ozempic hurt me really bad. I never made it to weight loss dose… i stopped after a few weeks and now six months later relentless abdominal pain….
Thanks for your testimonial. I was always curious but scared. Glad I haven't tried it out.
Please have a ct scan of your liver and pancreas. Same thing happened to my sister. Please get checked. A liver function blood test isn’t conclusive, don’t rely on thi😢test. You must look at the ct scan
I lost 40+ pounds through time restricted eating and regular dog walking (always did the dog walking-just made sure to take one 4-5 mile long walk most days). Over 65. No side effects.
I’m sorry this happened to you. Sounds painful and scary.
Haha. And all you had to do is start exercising and stop eating like a 🐖.
I take Semaglutide and started working out 5 days a week with 10 minutes of cardio. Lost 80 lbs but have gained lots of muscle mass. I've seen people take it but don't work out they do look sickle. I take ammonia, protein, vitamins .
Is that a typo, or do you really take ammonia?
@@higherresolution4490You need Ammonia only when you are Not Eating a Proper Human Diet 🥩🐟🧈🥓🥚
He obviously is a VEGAN
Yup. U def should have resistance training and eat enough proteins and healthy fats to minimize muscle loss
@@higherresolution4490 Probably aminos
@@higherresolution4490 He is likely referring to AMINOS, zero chance he takes ammonia 🤡🤡🤡
Any weight loss is going to include muscle loss. No one bats an eye at bariatric surgery. I will gladly give up 6 pounds of muscle to lose 200 pounds of fat and get my A1C down, while developing a better relationship with food.
There's no shortcuts in weight loss, everything has consequences. Steady weight loss is the only way with long term success.
After a lifetime of believing that, I started intermittent fasting, zero sugar and super low carbs. At age 64, I was slowly dying with long covid, so did this for health. It improved my health VASTLY, and as a bonus, I lost 2 sizes, and take zero meds (now I'm 66).
@@jennifermarlow. Yep. The key seems to be SHORT PULSES, like IF, or water fasting for 3-4-5 days, stuff like that. Or extreme calorie restriction for similar periods. Longer extreme restriction can cause problems, but the short stuff works good. Go hard and heavy for a short time, then back off and stabilize, then go hard and heavy again.
@@jennifermarlow.that’s awesome! The point may still stand though. When you lose weight you lose muscle, and probably bone density as well. Maybe you didn’t. Hopefully you didn’t lose bone density at 66 years old. That’s very important. Load bearing activity increases bone density🙂
@@jennifermarlow. Then you can keep on believing that because thats what you did. Breakfast is a scam, literally.
I believe that those who take shortcuts doing hard things miss at least half of the benefit of the result. Building the proper mindset necessary for long-term success carries over into every other aspect of your life. Persistence, endurance, discipline above and beyond what most people around you posses.
It may not be for everyone but Mounjaro damn near saved my life. It’s been a game changer as a tool in my arsenal to get back on track with my health goals post menopausal, post cancer, and working on staying symptom free with autoimmune arthritis. Now back down to the starter dose as my maintenance for now. (Luckily I started with a high level of muscle from early training.) But thank you for letting people know about this danger. 😃
Fellow Mounjaro taker here. I think quite often men underestimate the devastating effects of hormone imbalances that are unique to women, resulting from problems or changes in our reproductive systems. These problems present immense challenges for weight loss. In general, men have an easier time losing weight than women anyway, but you add something like PCOS or menopause to the mix, it's damn near impossible to lose a significant amount of weight without practically killing yourself. Mounjaro has been a gamer-changer for me as well, but I also agree that these drugs aren't for everyone and if you can do it yourself, it's better. Every individual has to make their own risk/benefit assessment and determine if going on one of these drugs is right for their situation. For me it was, do I keep watching my weight and A1C climb despite my best efforts and keep getting sicker and sicker, or do I take a chance on one of these drugs to help me take back control? I don't know what the effects will be long term, and I'm nervous about that, but for now I feel I made the right decision.
@@ladykilgore2337 APPLAUSE. The anti-Ozempic ppl, like the anti-GH ppl, want everyone to do things the "natural" way, but that is not possible for everyone. This "natural" crowd overwhelmingly consists of men, and typically younger athletic men -- like Attia. A male athlete like Attia cannot understand how difficult it is for people who do not have his enormous advantages.
@@alan2102X I mean no disparagement to men overall nor to anyone who has the ability to do it naturally, but there is definitely a disconnect experientially. Thank you for your kind support. ☺
Mounjaro did not work for me - I ended up twice in ER with excruciating pain - developed gallbladder stones. I would not recommend it to anyone. I get that many are losing weight on it but the pain I went through was worse than giving birth. If you are lucky that you get to lose the weight and not develop such a bad side effect then you are really lucky. I guess one will not know until they try, each body is different. If you do not have insurance never take the chance because the ER visits are extremely expensive around $30K per visit!
@@ForPeaceOnly Gallstones are not an uncommon thing in people losing weight very rapidly.
How many GLP-1 adverse effects are due to ppl taking high doses and losing weight too fast? IDK, but probably a lot.
I'm 20kgs down after three months on the carnivore diet. Good food and some exercise is all you need.
I’m taking semaglutide. I’m running an experiment on myself.
I’m an experienced lifter - been training over 10 years. I’m 210 lbs, 5’7”, around 30% body fat.
I gained about 30 lbs in the last five years - some muscle, no doubt, because my lifts have improved - and I attribute this to increased calorie intake from the stress of starting a business and having two kids.
I’m still lifting 3x per week and I’m taking semaglutide. I’m curious to see if I see much muscle loss.
Will check back in and let you know 😅
If you do muscle training its not true.. I've gained 5 pounds of muscle the last year by training, and been on Ozempic for like 2 years, because of diabetes...
So, I’m a T1 diabetic that’s been on mounjaro for several months. It has had a huge impact on my blood glucose even as a T1. Doc and I didn’t expect it to be that significant. I generally run a 500-1000 calorie deficit. I aim for 170gr of protein per day. I’m down 13% with minimal muscle loss so far but then, about 2% of the weight was muscle. I push pull legs at least once a week. So that is obviously helping keep this in check.
Basically, they’re prescribing this and there isn’t enough education on maintaining muscle mass and proper diet. People want to take the pill and then continue to eat like shit.
As it is, what I do is based on my own knowledge plus the help of your channel, Renaissance Periodization and Nippard.
Mitopure is ridiculously expensive. They have to bring the price point down at least to a third of current pricing. Their charging "magic supplement" prices.
Thomas, the study said they lost 15kg, not 15 lbs. 15kg is about 33lbs. Look at time signature 3:05. Even more disturbing...
Not sure Thomas cared about accuracy and science....he has a team...they make scripts for him....hes here to make money....he's not someone you should take health advice from.....he's on steroids and starves himself.
But it didn't seem to say anything about lean mass, the highlight just mentioned body weight
@@defeqel6537 why would you get advice from Thomas delauer at all? The guy is an actor...not an intellectual....he takes steroids and starves himself.to stay lean because this is.HIS MONEY
He doesn't care.about health and is just reading scripts that his team makes for him
That highlighted section was talking about overall weight loss not muscle loss. Don’t know why he highlighted that part when not talking about that but, anyway.
WOW
I appreciate this video, thank you 🙏🏾
There’s many other reasons glp-1 agonists work. Not related to insulin sensitivity. Weight loss always causes an amount of muscle loss along with fat loss. Nadolsky is correct. If you look at the studies. The studies show people are then able to exercise easier, this also has an effect on the family leading them to also exercise. There are many other positive effects of Glp-1 agonist, Gip agonists, positive heart effects, kidney effects, less food noise, less compulsive behaviors.
I recently started Oz to get my A1C down. I am well into my workout regiment of 5-6 days a wk, including 3-4 of those days being resistance training. I make sure to supplement, protein, EAA's, vitamins and water. I also make sure to eat at least 1600 cal per day to make sure that I'm not starving myself. doing regular resistance training should counter the muscle loss from being on Oz for the purposes of diabetes, right? my goal is to get my glucose back down to a sub 6 and build muscle while losing fat.
Ozempic for me is perfect at .5mg. Almost 2 months, no bad side effects, and I've lost 10 lbs. My ravenous hunger is completely gone. I eat 160 grams of protein per day, strength train, and have only lost 1 lb of muscle. The nausea is from pigging out, so just don't overeat.
Yeah, only people I see really complaining about it are the edge cases (which every medicine has) and people who haven't ever taken it. Study after study is showing its effectiveness and potential life extending benefits. Everything from reduction in cardiovascular disease, diabetes, brain deterioration and even addiction to nonfood substances.
@@nicholascolletta1777
The person you are replying to is the edge case.
Rip to your kidneys. Not only are you taking that trash but throwing 160g of protein on top
@@MiLitioN
Protein doesn't damage the kidneys.
@JasonBuckman ok my man. When you wanna come back to reality let us know.
I took Ozempic and about 2 months later I hade horrible gastro that lasted 2 weeks. My mum suspected that because it takes so long to clear the stomach on this drug, if you eat something bad it has more time to stay in your system and cause problems.
Thanks for the education
Some of that “muscle” loss is inter muscle fat from metabolic syndrome.
Awake doctors are changing peoples lives with low dose Ozempic. I wouldn’t be to quick to right it off yet. Low dose seems to have no side effects.
Yes most ppl who start at higher doses have the most side effects.
So take protein, urolithin a, creatine, taurine and possibly mild steroids along with ozempic. Also lift weights.
Great Video! Thank you 🔥👏💪🫶
Thanks Thomas I appreciate all your work 🌹🌹
Correction: at the 3:12 mark, you say "...lost 15 POUNDS of muscle", while the video showing an excerpt of the study shows "The change in body weight from baseline to week -15.3 KG (kilograms) in the semaglutide group..." So what is the real 'poundage' of muscle loss?
Yeah I caught that too!
15.3kg x 2.2 = 33.66lbs
I don't think we should make a big deal about muscle loss when the drug prevents something more important which is life loss
My doctor put me on the keto diet rather than on Ozempic. I'm down approx 10 lb, which is t an issue. Ozempic was primarily meant for managing diabetic hyperglycemia. The diet works at least as well, as I have no more high blood sugar, my thoughts are clearer, and I'm happier.
Weight loss just makes you healthier if you lose fat and protect muscle. This is important to reverse insulin resistance. Thinking that it is weight loss itself that makes you live longer is pure ignorance.
For actual diabetics.
Not for people who want to take the lazy way to lose 15 pounds.
Very informative. I take everything Thomas has to say into consideration. He does the research. He reads and understands the literature. Thank you for sharing.
Intermittent fasting …. Everyday is the way …. No drugs . No seed oils . Low sugar . No soda. Minimal processed food.
So I would ask those critics of glp 1 agonists to research proper dosing. Most initial doses of the injectable given are way too high as a starting dose. Women who have experienced the misery of perimenopausal/menopausal hormonal weight gain and insulin resistance (significant abdominal weight gain despite "doing everything right' - speaking from experience here) are a population that seems to get ignored in this conversation. Not everyone using glp 1's needs to lose 100+ pounds due to poor lifestyle.
Dr Tyna Moore lists some great studies in her extensive research on peptides.
Seems like remaining obese is the higher risk.
Yeah, it’s obesity treatment so only obese people should use it and it’s temporary. It’s a means to an end, it’s a valuable medicine for some people. It’s effective and comparativly safe
@@user-nz4ux4cw2z It's for diabetes.
Yes it's worse, but not actually exercising and using these drugs long term is worse. A lifestyle change is mandatory for actual results.
Amen.
Or having the muscle mass of a 80yo
Always love your channel ! Yes review the science and data !!
I can’t imagine taking a drug for something you can do yourself, and for free. Do your intermittent fasting, lose weight slowly, don’t make drug companies richer.
Lean muscls is incredibly important for all assets of life. You dont need to look like a bodybuilder but you should be able to walk up an incline without melting. That is horrifying news. I'm glad i take accountability for my life and dont look for shortcuts at the expense of longevity. Trading obesity for anorexia is not the play. Get healthy habbits, track your calories, get counciling to overcome any emotional attachments for food and stay away from fad diets. You will be fine. I just lost 40lbs naturally over 7 months. It took work, it took dedication, but i did it myself and i now have ideal health markers. Dont be a sheep, its benicial for the health care system to treat rather than prevent.
Blah blah blah...No one cares
@@nik07nik you're right, not many people care to take care of themselves and prefer a life a mediocracy, I don't blame you, it's easier to follow the herd which has become obese by choosing highly processed foods over healthy foods. It's funny that people care enough to seek out life altering drugs and fad diets but not enough to take a few minutes and learn the staples of being healthy.
@@Girthquake9 Sorry pal, just read thorough these post and everyone want to talk about their weight loss (horrible term it should be fat loss) Bragging about getting out of problem they created by their own sloth, gluttony and stupidly .
@@nik07nik while I agree it's not much to brag about, it can hopefully be a motivating success story for others that keeps them away from prescription drugs
@@Girthquake9 it’s the virtue signaling culture… Look at me look at me look at me… You don’t mention that you were the fool who got yourself into that place to begin with
Urolithin A is available from MANY different places. Curious on What makes this brand worth 100 bucks more.
Because they're a sponsor... 🤑
This was a good video it was very helpful.
My daughter is nearly 300 pounds, has PCOS, an A1C of 7.1 and other issues that comes with obesity. I got her doc to prescribe Ozempic. Its better to take a medication than to see her get worse and worse.
I'm only on the beginning dose and it's really helping me not crave sweets so much. I'm no longer gaining weight rapidly like I was post hysterectomy. I eat a lot of protein and now that I can exercise I am using weights.
Don’t worry, keep the protein intake high and move forward. If you start feeling badly or see any red flags, stop.
You are in a similar situation to my mother, she also had a hysterectomy and low doses of semaglutide (given by me) have really helped her kickstart her weight loss.
Good don't skip exercise,and get off ASAP
@@-whackd That's sad. I would not risk stomach paralysis, and though my mother was an abuser, I wouldn't even do that to her. People are losing their common sense. smh
"Ozempic face" happens to ANYBODY who loses a lot of weight whether it's from gastric bypass, gastric sleeve, weight watchers, Jenny Craig, keto, Atkins, intermittent fasting, carnivore etc.
That is very true.
People are always going to hate.
True. May maybe if a really young person lost slowly, they may not start looking gaunt. When I was 34, I began yoga and working, eating better again, and lost some weight. I remember my dad saying, "you've lost enough weight, you're starting to look gaunt."
My wife took ONE shot, we ended up taking her to the hospital. She threw up for 3-4 days straight, couldn't keep anything down even water. She had to take a prescription stop-throwing up drug for a week after that one shot, and it only made it tolerable, she still threw up every couple hours or if she tried to eat anything.
I am borderline diabetic. I did have a crappy diet before. Now I have lean proteins, veggies and fruit, and limit my carbs. After 2 months I feel much better and am noticeably thinner. It’s not easy, but it’s worth it.
And how much protein did they eat? How many did resistance training? Again, why not tell people how to take it properly?
Thank you!! Ozempic is a tool, not a replacement for better food choices and exercise. I have taken Ozempic for quite a while now, with no ill effects. My A1c went down, and I lost weight. ANY medication comes with a certain amount of risk. I wish people would educate themselves as far as pros and cons and not jump on the villifying Ozempic bandwagon.
Nope. It is just the beginning of Ozempic. This is going to be sold and sold hard. I expect it to be on the FDA list of approved childhood treatments and get exemption from claims of compensation.
I have nothing to say about Tirzepatide but great things am losing the weight beautifully and I feel amazing. Since I started I feel healthier. I Started on Feb 1 24 down 43 lbs so far I love the way I look now. So grateful 😊🎉
Big Tommy!
We do not agree on thumbnails but that is a beautiful shirt!
Good video!🤙
I started ozempic. I immediately had severe constipation problems. I eat a good percentage of spinach, squash, broccoli, etc. I was going 3-4 days constipated pain. So I finally convinced my doctor to stop his advice. I felt back to normal in about a week. Do the doctors receive a “kick back” for prescribing it?
If the drug is still patented, you can bet your ass they receive kickbacks for prescribing it.
Semaglutide is not patented. It is not even a drug, but an endogenous peptide produced by the body. The delivery method (the auto injector) is patented. You can easily get semaglutide prescribed from a compounding pharmacy and do the small injections once per week yourself, and it will cost you about twenty bucks a month.
It is the delivery method that is patented--the auto injector.
Semaglutide is actually affordable if you have a doctor prescribe it from a compounding pharmacy and inject yourself. I'm talking about $20 bucks per month for a reasonable dose.
The reason why the compound semaglutide is not patentable is because it is an endogenous peptide produced by our bodies.
No we don’t receive a kickback. That’s illegal. It works in over 95% of our patients. There are patients that just cannot tolerate it.
But I would like you to realize that doctors are human and in reality, you can take a lower dose to start out. Have you ever drank 1/2 of a container of water by chance? You probably have. It’s the same thing with medication. You don’t always need a full tablet of medication (that’s why tablets are sometimes scored?) or a full typical dose. Everybody has different amount of GLP receptors.
Humans are inherently lazy because we don’t have to hunt or gather for our food. On top of that, our food is of rather poor quality. Your body is actually going after nutrients - First - so the cells and the system can operate well overall. Then probably calories. But there is plenty of stored energy in a body to last quite a while. it’s much easier and more effective to eat a diet that is more vegetarian based. Good quality meat or eating eggs in moderate amounts. With our patients, we generally want them to eat around 0.6 to 0.8 g Protein per pound of weight per day, drink 100 ounces of water per day and get 30 minutes of strength training with full body three days per week. It doesn’t have to be super intensive. When you have a catabolic state that these medications can cause (since you’re eating less) - your body goes into a state of distress, thinking it’s dying. So the adrenal stress is already being caused by diet so aggravating it with overtraining will make it worse.
*Moral of the story is that think of this medication like a full plate of food. You don’t have to eat the whole plate and you don’t have to take the full dose in the beginning. It has a click dosing system…
@@trentknight8661 jeez, Doc, tell me everything you know. Yes, I started with a small dose. Yes, my portions with Whole Foods were smaller. Always included leafy greens and fibrous veg. And, 3-4 days of painful and difficult constipation. I refuse to take trendy medications and advice on health issues from Oprah or Kelly Clarkson.
This is what happens when we look for short-cuts instead of actually fixing the problem!
this is what happens when people abuse a drug meant for diabetes, not weight loss
I’m so happy u have no idea what ravenous hunger feels like. My bias is very natural based. I literally do everything “right”. Nothing suppresses my appetite. My input always matches my out. All Zep Bound does is reduce my hunger to a normal person. But like I said I have everything else dialed in. I used it for a year and lost 70lb while maintaining my strength and muscle. I haven’t taken it in 6 months and haven’t gained an ounce. And guess what….my hunger hasn’t come back.
@@geekspeak1066 Comment was related to society as a whole, and not individuals: If we as a society, were focussed on addressing root causes it may have become apparant what ravenous hunger may be attrbutable to (deficeincies, gut microbiom etc.)
If it were me, I would still speak to a high quality functional medicine doctor to possibly get some answers
It's going to be a lifesaver for many people.
Facts💯
Just one correction sorry. You’re more than just some dude on the internet! The work you do, the research you do makes so much difference! I’m grateful ☺️🙏🏾
Yes, this makes sense. Thanks.
I know someone who took Ozempic for 3 weeks on/2 and weeks off. lost a good amount of weight slowly or at a more moderate rate. he looks great and has maintained the weight off. he was loosing about 5 lbs to 7 lbs per month. he has a summer body now.
I love your channel. Have you seen the news in the UK. They are saying that it has other benefits and these are from studies also...
Age 28 i weighed 230 pounds with a bmi somewhere between 30 and 40 today i stand at 168 pounds and 13% body fat at 34 years of age... im in better shape than the majority of guys in their early 20's . I perform at the level of a pro athelete 2x10-15 mile rucks + 30 pounds weekly. With 3 hard days of calisthenics resistance training weekly. In the last 2 years i tore a rotator cuf (6 month recovery) and got upcer in my left eye along with a nasty sinus infection causing me vertigo (3month recovery) my body fat was tested yesterday... we dont need anything but ourselves
The doctor tried to put me on Semagultide and I refused, cut out sugar, eating whole food and cutting processed food, and exercising 3 times a week for 50 minutes. It has been 14 weeks and I am down 18-19 pounds, 10 inches and gain 4% muscle and my blood work has improved across the board. I’m really sedimentary and recovering from a car accident so anyone able can do this. If possible try to eat better and move more for your overall health ❤
I have no idea where you got the idea the participants lost 15 lb of muscle during the treatment. I read the study, it doesn't list any numbers about muscle mass loss, it only mentions that they did lose some lean mass. The figure you keep showing doesn't even say what you are claiming, it's talking about total body mass and it says 15 kg not lb...
Good catch - lean tissue doesn't necessarily mean ONLY muscle. You also lose vascular tissue, cellular membranes, and even your organs shrink a little bit as you downsize the rest of your body.
@@katarh right, but my point is the numbers he "quotes" are wrong, not only is he saying LBs rather than KG, making me doubt he really even read this stuff, but that figure isn't referring to lean mass, it's referring to total weight, so there is no way to know how much was lean or not. It's such a blazing error I don't know how it let this get released on youtube.
It’s common sense obese people, who CLEARLY ARENT WEIGHT TRAINING OR EXERCISING, are losing muscle.. along with fat.. BECAUSE EVERYONE who looses weight looses muscle.. I enjoyed the video but when he’s pushing some supplements at the end.. I start to ask questions.. 😂😂😂😂
You looking for a summary? I've got you covered, you beautiful, lazy genius.
GLP-1 receptor agonists, like Ozempic, help with weight loss and glucose control but can cause muscle loss, often noticeable as "OIC face." Studies, such as those in the New England Journal of Medicine and Diabetes, Obesity, and Metabolism, show significant weight loss and reduced HbA1c levels. Common side effects include nausea (11-20%) and vomiting (10%). Experts, including Dr. Peter Attia, are concerned about the significant muscle loss observed in users. To prevent muscle loss, resistance training is crucial, along with supplements like Urolithin A, Taurine, EAAs, and Creatine. Prioritizing sleep and protein intake is also vital. Proper exercise, nutrition, and supplementation can help mitigate muscle loss during weight loss with GLP-1 agonists.
I tried saxenda it gave me really bad side effects, mainly bloating couldn't do anything, thanks to you and Dr berg I learned about keto, now I am 13 months in keto + IF down 53kg, not so far from my target weight.
I took myself off of it after 3 years. I started having digestive problems.
A 1% reduction in HbA1c is significant? Hardly! It's completely insignificant. I'm Type 1 45 years and have developed stubborn, hereditary metabolic issues of late. Ozempic is my miracle drug with almost no side effects. Can't speak highly enough of it! It definitely has its place.
But this might put big Pharma and Thomas out of a job😉
@@amydean269 highly doubt it.
My doctor recommended i start taking ozempic for fat loss ( this is before it got popular) i said no thanks ill lose weight the natural way and ive lost weight ( not as much as i wantbut still pretty good) and im glad i didn't take it ill stick to natural weight loss thanks
Well obviously the doctor was wrong... he thought that you did not have the stamina for fatlose yourself.... But you did obviously... NOT. Why the fuck go to a doctor if you know in advance what to do WITHOUT a doctors advice. THE DOCTOR WOULD NOT RECOMMEND THIS IF YOUR ARE NOT OVERLY OBESE!
Hoping to get sleep back into my equation very soon. Waking up 1am for work is very hard no matter what time you try to get to sleep. Moving from 1am to 5am will be huge difference for my circadian rhythm. Right now I get 4 hours on a good night.
I Have Lost a Lot of Muscle Mass on ozempic. I am looking to come off Ozempic due to HbA1C being back in normal range.
I have lost muscle mass in my face also.
I will be getting back into the gym, sleeping more and taking these supplements.
See how I look in 3-6 months
Significant muscle loss on a GLP 1 is completely optional, as you mentioned. Prioritize protein, strength train, and get good sleep. They are game changing if you do those things.
If people were actually prepared to do those things, they’d lose weight without it and without the associated risks.
In the British press headlines today some of our top cardiologists are now claiming sensation early results for the treatment of heart conditions. They are claiming the drug could be as revolutionary a treatment as statins and should be a treatment of choice in the future!
Wow, and statins are killing MILLIONS. The UK (and NHS) has really gone to a dark place. Sad, just like here in Canada.
I eat like a robot 90% of the time but I’m on vacation living it up right now. Currently headed for a donut and i felt the need to share this hahahaha
I took Ozempic for a year for Diabetes and weight loss...didn't ask for it like thousands of people do...was given it by my primary doctor...I had Diabetes and I was over 300 lbs and at the time I was on Januvia and it had stopped working...Ozempic almost took my life and now that I'm off of it and I have lingering health issues because of it...I can honestly say these health issues are from Ozempic, even without a doctors diagnosis( which they will never give me one...I've tried) because I didn't have these issues before Ozempic...sad that we are the human guinea pigs for this drug
Initial nausea resolves for most after a month and if you keep protein high and lift weights you only lose as much muscle as you would if you lose the weight slowly.
“Ozempic Face” is the “meth mouth” of Hollywood
I’ve been on semaglutide for 2 years now. I have not lost any muscle. I work out 4-5 days per week at orange theory and also do 5k’s. I do not have Ozempic face. My ha1c, glucose and insulin are amazing now. I’m also a health coach for a wellness company and have MANY patients on semaglutide. I don’t have one with “Ozempic face.” I also have had probably 4-5 people who had vomiting on semaglutide, so we switched them to tirzepatide (Mounjaro) and they were fine. It’s been a life changing medication for so many!
Ozempic is giving people the ability to do a hard cut, but doesn’t teach them anything about how to manage doing it well…
So glad I did my weight loss and muscle gain all by myself. Frustrating though that all lot of people think I am taking Ozempic rather than hard work (exercise and nutrition).
If you need to lose 150lbs, exercise and nutrition may not be sufficient, at least not in a reasonable timeframe.
Getting fat off you or keeping muscle. Both are important, but for a person that is obese, getting the fat off is far more important for health. Muscle can be rebuilt. Losing fat and becoming regular weight, that has huge effects on every aspect of your health, especially if you’re obese to begin with.
If you’re not obese but overweight, then I’d say that yes keeping muscle becomes important but again my personal preference is getting into a very healthy weight range over building muscle. If you’re older though, then keeping muscle also becomes important.
If ozempic can help people to stop stuffing their face with food and lose weight, that’s great. Personally I used to use ozempic but it didn’t work for me. So I stopped using it and did a combination of intermittent fasting, extended fasting, low carb. Now I’m graduating to meal planning and nutrition.
I have type 2 diabetes and was on ozempic for almost a year and I quit because it was not working for me anymore. I never lost a lot of weight and I was having to take insulin and had trouble with muscel loss. I now have no problem with my sugars since. I now take berberine to help me.
When I was anorexic I lost a significant amount of muscle mass. It fucked my body, caused significant weight gain, and ruined my metabolism. Being thin at any cost is NOT worth it.
It's abundantly clear to me that people in the comments have no idea what they are talking about. The drug doesn't cause you to lose weight. The drug affects hunger and digestion - which then makes you feel fuller for longer and drastically reduces food noise.
So if you eat just as much as you normally do, you won't lose weight. However, the odds of that happening are low given the effect it has on cravings, food noise, and appetite - as well as how full you feel.
People on the drug still have to change behavior to make it as effective as possible.
This. Both Ozempic and Mounjaro lowered the volume of my food noise. Mounjaro was better at it, didn't have such awful side effects, and also tackled some of my inflammation. However, it's in short supply so I'm back in Oz *ha* These drugs have helped me to initiate and maintain keto and the keto is causing me to slowly lose weight.
@@skyethebard And that's the key word - slowly. Everyone here is acting like it's a "shortcut" or some form of "cheating." It takes a long time and consistency to hit your goal weight.
Do we tell people with ADHD just to get better at focusing? Do we tell people with depression just to get over it and stop being sad?
I'm convinced people are just so miserable that they need someone to feel superior to in life.
"Hey fatty, just stop eating!"
"NO NOT LIKE THAT, THAT'S CHEATING!"
And then they wonder why people are willing to put up with the side effects? Insane.
@@rewskyExactly! The medication itself isn’t making you lose weight. It’s the behavior modification that it ultimately facilitates. People who are against the drug just say “eat less” even though that’s precisely what it helps you to do. I feel like the naysayers *want* to see people fail.
My mom has been taking it for Diabetes. She was already very skinny when she started it. She has lost more and more weight, to the point that she's skin and bones now. Her doctor is going to take her off the Ozempic if she loses any more weight.
I've been on ozempic I also take Testosterone. I'm losing weight slower than most people. I think this is because I focus on protein and I believe the Testosterone is helping me maintain my muscle mass. I push dumpsters around daily and haven't seen any decrease in my strength. I also don't know anyone with vomiting and nausea. No pooping is my issue and have to take miralax daily.
Repopulate your gut microbiome with good quality probiotics.
I gained 8 pounds over 16 weeks on ozempec …. No bs… gained a lot of strength and muscle… didn’t affect my appetite really… only sometimes I would get full quicker
Was on tirzepatide for a week I’m on day 7, been sick all weak battling low blood pressure and dehydration due to it acts as a diuretic which I didn’t know my kidney hurt, stomach hurts, anxiety. It stay in body 10days waiting for it to wear off. Never touching it again. Don’t take it. Not worth it. Some do great but many will not and have alot of side effects especially with ozempic. Now I’m focusing on intermittent fasting calories and high protein.
I personally believe that it has more to do with lifestyle choice. The body is fantastically adaptive. If you're in a caloric deficit, and don't exercise or challenge your body, your body will selectively get rid of that which is most metabolically expensive, which is muscle tissue. However, if while you're in a caloric deficit, you can put a significant strain on your body physiologically through exercise, you will signal to your body that you still need the muscle in question, and you will preferentially lose fat.
I've been on Tirzepatide for 7 weeks, I've lost 17 pounds, but am eating at least 200g of protein per day, walking at least 4 miles per day, and have continued to lift weights just as heavy as I did prior to my weight loss journey. So far I haven't lost any strength, which would seem to indicate I have not lost much, if any, muscle. I am however going to get a DEXA scan here in the next couple of weeks just to make sure.
The problem is not that you lose muscle mass , the problem is where you lose that muscle mass. And from what i see online is mostly small core muscles that are hard to train or to regain back , im pretty sure that's not how you lose muscles on a normal dieting plan.
At my current age and composition, at best, I will lose fat and muscle in a cut at a ratio of about .5-.7 kg muscle mass for every 1.0 kg of fat per week. Usually scaled down from that a bit. That is "muscle mass" as measured by the dorky smart scale, though, which includes water and glycogen, etc., in the tissue. Not sure about actual fiber loss. It comes back fast, in a similar ratio in the other direction. Just looking at rough figures.. 15 lbs is only around 7 kg, and we are talking about people who lost over 50 lbs (~25 kg) of fat. That seems pretty standard for people at high fat percentages.
I’m a 71 year old woman. It just took me 7 months to lose weight. I don’t know how much weight I lost but I’m guessing at least 60-70 lbs. I was eating around 800 calories a day. I am in the process of upping the calories but my mindset is to keep eating less calories. Today for the first time in my daily eating I ate 1200 calories. I want to resistance train, I used to years ago and I loved it. Problem is I have an umbilical cord hernia and I don’t think you’re supposed to resistance train with that. I have a lot of hanging skin from years of losing, binge eating and gaining so I really need to resistance train. I do exercise videos. I take supplements and I’m really kind of tired of adding more things to take every time I watch a video. Plus I’ve lost all the weight I want to lose so is it still beneficial if you’re not trying to lose weight? I had high blood pressure and now it’s low and I’ve been having issues with low blood sugar so I’m dealing with that and it’s frustrating.
Not worth what risk? The risk of staying obese is pretty bad as well.
This drug is saving lives.
It takes lives. There’s no magic pill. You’re not getting to the root cause, it’s a bandaid.
Ozempic has been perfect for me. In 12 months I've lost 60 pounds. A1C from 8.7 to 5.1. Gained 7 pounds of muscle. Ozempic should just be a helper. You still have to take responsibility for yourself and for your body.
I am a diabetolgyst and I am also a dietitian. I have been advocating the muscle loss Ozempic causes since it has appeared on the Romanian market. I also noticed that the fat mass increased, so no true weight loss was present in the true sense of the word.
Thomas keeps saying pounds but all of the highlighted text says kg?
It was lbs on the muscle loss. The highlighted portion is showing total weight loss in KG
The problem is that you can't take ozempic for a long period of time. People would probably think " nah I'll just take ozempic and sit on the sofa and it will work", at the end after stopping ozempic, with less muscle mass it will be easier to regain the weight normalized again the metabolism.
Yeah let's spend money on things that will probably give us nausea instead of just increasing the steps we do in a day and do just a little bit of bodyweight workout...
I do both. on a cutting diet, I take semaglutide, work out and eat a carnivore diet. On a bulk, I eat a carnivore diet plus lots of cream and dairy, don't take semaglutide, and work out.
It's great, makes dieting easier, costs less than $10 a month at the doses I use.
How come you cant take ozempic for a long period of time?
I know someone who takes the shots, they're lazy as hell, smoke a lot, and they look like sh!t even though they got skinnier. They were off the doses for about 2-3 months and gained their weight back. They also dare to give health and weight loss advice while all they ate in a day was a bunch of candy and a bag of chips.
It's seen as a live long drug. Ppl who stop gain over 70% of the weight they lost back within the first year.
@@beewest5704 wow thats crazy
I have never taken ozempic, in the last year and a half, I have lost 75 pounds and build a lot of muscle. However, I don’t blame anyone for taking ozempic. Finally something that helps people lose weight that works and people just poop on it. So many people struggle with there weight, and yes, a lot of it is because of not being able to control how much they eat and the overwhelming cravings for high calorie food. Some people need help, no reason to hate on them.
congrats!! how did it come off?
@@KQDYMagallaz started with eating in a calorie deficit of 500. Tried to get use to eating appropriately. Then added in walks. Eventually added in working out. I also found a sport I like, and it is beneficial to weigh less (not be over weight) and gain muscle. So that was a bigger factor for me to do the workouts/diet even when I didn’t feel like it. I lost most of the weight in about 8 months. I do have really bad sugar cravings and carb cravings, like binge eating type. Which is why it took longer to lose the rest. Still haven’t found a “cure” to beat intense cravings.
@@KQDYMagallaz but in order to build and keep muscle while in a calorie deficit, for every pound I weigh I eat 1g of protein. All I know is it is sure as heck working. I am a woman and you can see the muscles 💪
@@KQDYMagallaz I also find it helps when you are in a lull to do something that makes you feel “pretty “ or “handsome “. For me, it would be getting my hair done or my lashes or a spray tan. Just something that gives you a bit of a confidence boost. Whatever that is for you.
@@terrie6738 your amazing, I LOVEEE what your doing!
While on Ozempic, then Mounjaro, I improved my body composition as long as I bulked up on protein and was consistent with weight training. It works. If you don’t workout nor eat the right amount of protein, you just lose muscle.