EP 90: Metformin, Berberine, Dihydroberberine: Which One Is Best?

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  • Опубліковано 16 січ 2025

КОМЕНТАРІ • 70

  • @robinham2796
    @robinham2796 8 місяців тому +9

    Finally got the book!!!
    You are a hero for women!! I took your list to my new hormone doctor and she said, we will test what YOU want to test!! She’s a NAMS doctor and I think she’s a good one!!!!
    Thank you Dr Tassone…

  • @mellie_mel72
    @mellie_mel72 8 місяців тому +31

    I tried Berberine last year to see if it would help my cholesterol levels. I eased into it with one pill a day (600 mg) for a week and two a day (1200 mg) the next week so I could see if I had side effects, which I never did. Over a period of 8 months my total cholesterol went from 200 down to 178. Triglycerides went down from 152 to 103. It didn’t do much for good or bad cholesterol though. I also did not see any weight loss on 1200 mg. When I started taking 1600 mg ( 3 a day) I lost 5 lbs, I cycled off shortly after, so not sure how effective it really is for losing more weight. I cycle off for about 4-6 weeks. I have less bloating on it. It does suppress your appetite and less cravings for sweet food. An interesting note is my PCP had never heard of Berberine.

    • @ShawnTassoneMDPhD
      @ShawnTassoneMDPhD  8 місяців тому +2

      It’s great stuff

    • @salviaprezzemolo2165
      @salviaprezzemolo2165 8 місяців тому

      @@ShawnTassoneMDPhD Have you seen it lower LDL?

    • @mellie_mel72
      @mellie_mel72 8 місяців тому +2

      ⁠​⁠@@salviaprezzemolo2165 No, it only went from 137 to 121.

    • @salviaprezzemolo2165
      @salviaprezzemolo2165 7 місяців тому

      @@mellie_mel72 A modest reduction, but my LDL is reading at about 200. Every little reduction helps.
      Thank you for letting me know. I appreciate the response. I wonder what @ShawnTassoneMDPhD has seen among his patients.

    • @privateeyeagent194
      @privateeyeagent194 6 місяців тому +2

      My Dr just started me on Metformin a couple weeks ago (off label for wt loss... I'm 66, have been post menopausal for 19 yrs, have no sugar problems & I eat Keto. I don't drink soda or alcohol & don't eat processed or fast food or at restaurants. AND since I'm just under 5', every extra pound shows 😬). I have Berberine but have never seen any difference with it.. I only just recently learned about Dihydro Berberine. My Dr had never heard of Berberine 🙄 I haven't lost anything yet since starting Metformin (other than my "normal" .5-1# daily fluctuations), but he eased me into it to help prevent side effects. I started whole 500mg tablets bid yesterday... Gosh I hope this works! I am desperate to the lose 40-45 pounds I've slowly gained over the last 30ish years 😢

  • @peterfallnbigl3582
    @peterfallnbigl3582 4 місяці тому +4

    Very logical and sequential. Excellent presentation...very matter of fact and no conflict of interest. Many thanks.. and as one woman commented is there a male-serving version of Dr Tessone?

  • @sunnyboy4553
    @sunnyboy4553 19 годин тому

    It's also used to get rid of intestinal parasites.

  • @thoth80
    @thoth80 5 місяців тому +7

    If you looked at a recent study on metformin and those who exercise compared to a placebo and what it does to VO2 max you may be shocked. I think I'll stick to berberine.

  • @desmondwagner7607
    @desmondwagner7607 Місяць тому +2

    I clicked on this by fluke. The picture mislead me. I thought it was Del Boy (David Jason) from only fools and horses. Nevertheless, I was impressed with the discourse and I am going to try the meds. 😂

  • @sblaising1
    @sblaising1 8 місяців тому +8

    I am concerned about using berberine because I have blood pressure that hovers around 90/60 almost every other day and sometimes goes into the 80's. I definitely don't want it any lower. Would this be a contraindication? Most people don't have to be concerned about low blood pressure.

    • @SassyO100
      @SassyO100 4 місяці тому

      I have naturally lower blood pressure two and in peri menopause and can only tolerate 500g once a day AM before first meal as two a day affected my blood pressure greatly… that I stopped totally. I’ve had a two week break and back on to 500g only as I felt great on it. I’m near to being pre diabetic so trying to do something about it. It’s a hard one taking supplements as General Practitioner Doctors don’t usually have a broad knowledge of alternatives. I’d seek some help from a Functional Medicine Practitioner or a Naturopath.

    • @GalacticWoman
      @GalacticWoman 3 місяці тому

      I've ordered some Berberine but I too have low BP 90-100/ 90-50 usually...now I am concerned

  • @roxanalabode
    @roxanalabode 7 місяців тому +4

    Can you please do a video on Tirzepatide Vs. Semaglutide? 💜💜💜

  • @rogerwilliamjefferson7490
    @rogerwilliamjefferson7490 7 місяців тому +2

    Please need a link to the endurance supplement. Thanks

  • @G.G.8GG
    @G.G.8GG 5 місяців тому +5

    I use berberine to head off diverticulitis. If i take it at the first twinge of pain, it will resolve in 2 - 3 days so i don't have to take Bactrim and Metronidazole, which tear up my entire digestive tract and make me wish for death. I also can't take fluoroquinolones. I continue to take the berberine 2 - 3 X/day for a couple of days after symptoms disappear.

    • @christineandcarlmilitz2883
      @christineandcarlmilitz2883 4 місяці тому

      How many MG do u take and where do u get it??

    • @G.G.8GG
      @G.G.8GG 4 місяці тому

      @@christineandcarlmilitz2883 I don't remember the dose of the one i usually take as I don't have it on hand right now. The one I do have, which seemed to work fine this last go round is 400MG and I take it three times a day.

  • @47retta
    @47retta 21 день тому +1

    Will a doctor prescribe metformin if I'm not diabetic yet? My ha1c is 5.5, glucose is 95, but insulin is 29. I'm overweight.

  • @glamlife8176
    @glamlife8176 6 місяців тому +2

    What are your thoughts on taking Berberine with a GLP1? Or with Repatha?

  • @johnkelly6265
    @johnkelly6265 6 місяців тому +1

    Thanks ,great information!

  • @KarenNelmapius
    @KarenNelmapius 3 місяці тому

    Very helpful.thank you very much!

  • @j-uk2189
    @j-uk2189 17 днів тому +1

    Does berberine lower muscle gain? Just like metformin. Does it lower mtor??

  • @nerylabrador2861
    @nerylabrador2861 6 місяців тому +8

    I stick to berberine forever. It has been a miracle pill. Very satisfied with this supplement.

  • @anneg8319
    @anneg8319 5 місяців тому +2

    Hello. My husband is 64 and, if possible, would you suggest an MD on UA-cam that would be trustworthy to watch for men? Thank you in advance.

    • @tarpara
      @tarpara 3 місяці тому

      Dr Robert Cywes

  • @liameneuk
    @liameneuk 7 днів тому

    But it is really difficult to buy pure supplements. Formulated ones may save you from some filler materials (inactive ingredients).

  • @LaLunaSkinandBody
    @LaLunaSkinandBody 8 місяців тому +1

    Can you add a link to your book?

  • @forsalebymb
    @forsalebymb 8 місяців тому +4

    I have had a radical hysterectomy in 2005 and been on Metformon since. I also take it because diabetes in in my family on both sides so dr told me it helps prevent that too. I have had no problems what so ever on Metformon and had no side effects. I also take B12 shots once a week.

  • @kenoshakat916
    @kenoshakat916 6 місяців тому +1

    The Endurance Company’s Dihydroberberine has vegetable wax (rice brand and/or carnauba), isomalt (vegetable), stearic acid (vegetable), magnesium stearate (vegetable), and silica. Am I looking at the wrong Endurance brand?

    • @ShawnTassoneMDPhD
      @ShawnTassoneMDPhD  6 місяців тому

      Nope that’s it

    • @kenoshakat916
      @kenoshakat916 6 місяців тому +1

      @@ShawnTassoneMDPhD aren’t those considered fillers?

    • @cindiesue1
      @cindiesue1 6 місяців тому

      @@ShawnTassoneMDPhDhi dr Shawn
      I’ve been taking 100 mg berberine for years not to lose weight but heard good for keto diet.
      I started on metformin a mo th ago 400 2 x day. No side affects nor weight loss
      I’m still taking berberine
      Should I start taking more berberine 2x day along with metformin? Should I only take one or tge other?
      Should u start taking more mg of metformin?
      Should I change my berberine to the new one along with metformin?
      Thanks for your help
      I’m 70, 5’4 140 lbs

  • @scoobybopbop
    @scoobybopbop 8 місяців тому +1

    Do you prefer the Epic endurance dihydroberberine product? Why is it tag as glucovantage? Does it means its a conconction of several ingredients??

    • @lisetteaguilar105
      @lisetteaguilar105 7 місяців тому +1

      I saw that too and was wondering the same thing

    • @esoteric.breadcrumbs.
      @esoteric.breadcrumbs. 6 місяців тому

      I saw less expensive supplements with the same labeling.

  • @MichaelV369
    @MichaelV369 6 місяців тому +11

    Are you my doppelganger? My wife and I thought this was an A.I. image of me.

    • @ShawnTassoneMDPhD
      @ShawnTassoneMDPhD  5 місяців тому +11

      @@MichaelV369 you are obviously then a very handsome fella

  • @pn3180
    @pn3180 2 місяці тому

    Can you make a video about Metformin & vit B1 interaction/ interference re absorption leading to Neuropathy(nerve damage)

  • @pinkpineapple2149
    @pinkpineapple2149 Місяць тому

    Im getting heart burn while taking berberine. Have pre existing acid reflex and heart burn issues. If i switxh to dehydro berberine will it be better? What dose?

  • @jenniferbryan295
    @jenniferbryan295 Місяць тому

    I've been using dihydroberberine for over a year. I take 1500 mg a day. I lost weight, however the scale has stalled, but I'm still taking it. I'm thinking of taking a break, but worried I could gain the weight. I've had no side effects.

    • @pinkpineapple2149
      @pinkpineapple2149 Місяць тому

      Did you have heart burn with dihydro berberine? Regular berberine was burning me inside

    • @ketokarbs3671
      @ketokarbs3671 13 днів тому +1

      Dihydroberberine doesn't come in 1,500mg

  • @jesseepudu5037
    @jesseepudu5037 6 місяців тому

    I have been on metformin n igot change in my nails weight loss anemia
    How can I adress it

  • @trinagreenfield5198
    @trinagreenfield5198 8 місяців тому

    4:00AM, perfect time! May I ask what time zone? I just Googled Texas, and I'm guessing it's central time zone. (PST here)

  • @annac6066
    @annac6066 8 місяців тому

    Dr Tassone- Do you recommend any of these options (or other options ) for women who are over weight with metabolic syndrome or prediabetes who are trying to lose weight and are trying to conceive (TTC). You mentioned no berberine for pregnancy or breast feeding women but what about those trying to optimize weight to improve fertility??
    You mention in most your podcasts your focus is perimenopause and menopausal women but do you consult for women TTC? Or do you recommend any specialists who CAN consult with women who are TTC? Infertility rates are rising& many women who are TTC are looking toward holistic approaches to help them. Thanks for any help you can offer!

  • @Painting1959
    @Painting1959 8 місяців тому

    I had a partial hysterectomy and they never gave me any hormones. I see my gyn should I ask for some. I’m 65 and my ovaries hurt. This was at a young age after my third child…but having problems.

  • @latashaakins-brown1820
    @latashaakins-brown1820 3 місяці тому +2

    Can u take Berberine with Tizepiatie or Semiglutide?

  • @jesseepudu5037
    @jesseepudu5037 6 місяців тому +1

    Can metformin be taken at the same time wth turmeric black paper at the same time

    • @keywestconch8
      @keywestconch8 4 місяці тому

      Yes. I take all those at three same time. 😊

  • @jeannedurco7405
    @jeannedurco7405 Місяць тому

    Why do people always talk about metformin when metformin ER has soooo many less side effects??

    • @ShawnTassoneMDPhD
      @ShawnTassoneMDPhD  Місяць тому

      Because 99% of the time insurance companies won’t pay for the extended release version would because the regular version is like five dollars so you may have great insurance or you may just pay for it out-of-pocket but most people can’t do that

  • @trinagreenfield5198
    @trinagreenfield5198 8 місяців тому +1

    This isn't aimed at the west coast. I'll catch you at a different premiere. I'm loyal, but 2AM is just not in the cards for me. (WA)

    • @ShawnTassoneMDPhD
      @ShawnTassoneMDPhD  8 місяців тому +1

      Not sure what you mean

    • @trinagreenfield5198
      @trinagreenfield5198 8 місяців тому +1

      Good morning. I’m actually watching this now. Wonderful and very insightful.
      My apologies for the confusion. I just didn’t want to miss this but it started at 4AM CST. I’m over here in the state of WA, and being with it live would have meant waking up at 2AM. But regardless, I’m watching it now and it’s terrific information.
      I hope you have a productive day!

  • @G.G.8GG
    @G.G.8GG 5 місяців тому

    I almost never buy a supplement with multiple ingredients as usually i will be allergic tobone or several of the ingredients. Exception: an herbal complex of adaptogens that helps me sleep.

  • @kevinmason6228
    @kevinmason6228 3 місяці тому +3

    This guy tested 27 brands of Berberine. It’s shocking how many brands are 0 or less than the amount on the M label.
    ua-cam.com/video/_2oLWLsoIUw/v-deo.htmlsi=LznUxAnBt5ClWUOp