Berberine shrinks Arterial Plaque, Study Shows

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  • Опубліковано 30 лис 2024

КОМЕНТАРІ • 634

  • @ericspry8402
    @ericspry8402 Рік тому +467

    Two years ago, a 2D echocardiogram revealed coronary calcification, which was preventing one heart valve from closing. My doctor indicated that no surgery was immediately warranted, and the issue would be monitored. I sought some way to address the calcification, and eventually learned about Berberine possibly being able to dissolve the calcification.
    I started taking Berberine as a daily supplement about a year ago.
    Last month, a follow up ultrasound of my heart found all valves to be functioning normally, and there were no signs of coronary calcification! I am so relieved and glad that it worked. Meanwhile, my cardiologist asked for the second time, "What's Berberine?"
    Go figure.

    • @Physionic
      @Physionic  Рік тому +47

      Congratulations :)

    • @nebojsa1976
      @nebojsa1976 Рік тому +6

      I mean, what what, if berberine dissolves calcification, that is bad, very very bad. Heart attack or most likely stroke waiting to happen.

    • @d_e_a_n
      @d_e_a_n Рік тому +28

      @@nebojsa1976
      Use more words. What do you mean.

    • @nebojsa1976
      @nebojsa1976 Рік тому +13

      @@d_e_a_n You have 2 layers. One is soft (soft plague) and one is hard (calcium). If you take away hard one with berberine, soft one will come out and cause stroke. Couldn't be simpler.

    • @FrenchViking466
      @FrenchViking466 Рік тому +1

      ​@@nebojsa1976I'm not sure it works like that.

  • @KatJaguar1122
    @KatJaguar1122 Рік тому +71

    It’s easy to see the correlation. Berberine lowers glucose and insulin, high blood glucose increases inflammation in arteries which causes plaque.

  • @theancientsancients1769
    @theancientsancients1769 Рік тому +175

    My dad took both Metformin and Berberine. Metformin affected his kidneys negatively and his blood markers for cholesterol and liver were not great . With Berberine his cholesterol levels went down and his liver markers improved and his kidneys too

    • @zzzxxzzz3248
      @zzzxxzzz3248 9 місяців тому +7

      Dihydroberberine is better

    • @zzzxxzzz3248
      @zzzxxzzz3248 9 місяців тому +8

      I avoid mRNA vaccine

  • @kurtisviktor3314
    @kurtisviktor3314 Рік тому +286

    My A1C was 6.8 / 8 months ago. I looked for ways other than low carb /exercise which I have been doing already for years to try and help lower my A1C. Came across some good info on Berberine. So immediately found a respected brand and began taking 500 mg a day. After 8 months and no change in diet/exercise from normal routine my A1C came back at 5.1 on Friday. I was pretty hyped about that. Having any cardiovascular benefits on top would be a bonus.

    • @stephx9759
      @stephx9759 Рік тому +9

      A1C levels can fluctuate because of vitamin deficiencies, supplements, stress, lack of sleep, and more.

    • @tokk3n-hj4xg
      @tokk3n-hj4xg Рік тому +19

      what's the name of the brand?

    • @jrmint2
      @jrmint2 Рік тому +4

      congratulations...sound like you are on your way to better health!

    • @chazwyman
      @chazwyman Рік тому +7

      What do you think is "low carb"? Maybe not low enough, or not complex enough. Not all carbs are the same. Clearly sugar calorie for calorie has a significantly damgaing effect on your A1c, more than the same amount of jumbo oats.

    • @kurtisviktor3314
      @kurtisviktor3314 Рік тому +14

      @@chazwyman My low carb lifestyle is basically under 30 net grams of carbs a day with an average of 10-15g of sugar per day 6 days a week. Sugar source would primarily be from Greek yogurt and natural peanut butter. I pretty much eat the same things everyday. And I tracked it for a month to get the average. 1 day a week I have my cheat day which might be pasta/sandwich/pizza/tacos/french toast…etc. Not an all day cheat day. Just one meal. And of course you have to live a little. Oh and I also fast a minimum 12 hours per day. Originally I thought my original results of 6.8 were the result of faulty testing, I couldn’t believe my A1C was that high. I told my Dr the next step would be ZERO carbs. What is strange is my blood sugar was 80 with an A1C of 6.8.

  • @robe4159
    @robe4159 11 місяців тому +61

    What was the dose of berberine taken in the study. Kind of an important piece of information.

  • @bruceg
    @bruceg Рік тому +233

    Just to be safe, I'm taking some chocolate cake along with my berberine.

    • @寿司食べたいな
      @寿司食べたいな 6 місяців тому +3

      Me too, I love my bourbon.

    • @mutantryeff
      @mutantryeff 5 місяців тому +2

      Try making brownies with urfa biber peppers

    • @AeriykTheRed
      @AeriykTheRed 3 місяці тому +2

      As God intended.

    • @curtissharris8914
      @curtissharris8914 2 місяці тому +1

      It's weird to hear how something that improves your risk means lowers your risk.😅😅

    • @paulhailey2537
      @paulhailey2537 Місяць тому +1

      Honestly , I do 100% Cacoa Dark Chocolate with my Berberine

  • @pondboy3682
    @pondboy3682 Рік тому +145

    As a hamster, I feel really left out for no reason! 🐹

    • @itsshepherd5618
      @itsshepherd5618 Рік тому +8

      That’s because u identify as pondboy, not as hamsterboy

    • @pondboy3682
      @pondboy3682 Рік тому +4

      @@itsshepherd5618 I didn't realize that putting your species in your username was required! Are you a German shepherd, then? Prounoun it, and distinguished from at least 5617 others by your number? 🐹

    • @dtnuh
      @dtnuh Рік тому

      @@pondboy3682 lulz

    • @kevinpalmer9619
      @kevinpalmer9619 8 місяців тому +1

      me too

    • @mutantryeff
      @mutantryeff 5 місяців тому

      Politicians are squirrel hybrids, but they just don't play in the road enough.

  • @phillialevine
    @phillialevine 8 місяців тому +6

    I’m so grateful that I found this channel

  • @conscience-commenter
    @conscience-commenter Рік тому +44

    For type 2 diabetics , the use of berberine along with K2 +D3 supplements, healthy eating and exercise is very helpful at removing arterial plaque . Just make sure you don't go overboard on dosage and eat consistently healthy.

    • @semiprolific774
      @semiprolific774 Рік тому +6

      What would happen if you went overboard?

    • @theancientsancients1769
      @theancientsancients1769 Рік тому +1

      ​@@semiprolific774My dad took both Metformin and Berberine. Metformin affected his kidneys negatively and his blood markers for cholesterol and liver were not great . With Berberine his cholesterol levels went down and his liver markers improved and his kidneys too

    • @danmarjenka6361
      @danmarjenka6361 Рік тому +3

      @conscience-commenter Define "healthy eating." Everyone's idea of eating healthy is different.

    • @SoloEmpireOfficial
      @SoloEmpireOfficial Рік тому +1

      Expand on the effects of “going overboard”. K2 (mk7) along with d3 aids in driving calcium from arteries into the bones.

    • @2nostromo
      @2nostromo 11 місяців тому +1

      How do you know all this? Are you an Oracle? Should I buy Anaconda Copper?

  • @betterplacetobe7896
    @betterplacetobe7896 9 місяців тому +19

    Best supplements for blood clots, plaque buildup and remove calcium from the arteries and yes all true from CT scan, stress test, bloodwork and echocardiogram. Berberine, K2 & D3, nattokinase and kyolic garlic with lecithin

  • @ericspry8402
    @ericspry8402 11 місяців тому +45

    Although French lillies sound like a great medicinal source, it's my understanding that recent studies found that metformin exacerbates neuropathy, and this effect is multiplied further by gabapentin.
    My first exposure to gabapentin was due to a bout with shingles that I had in December 2015. One year later, I was diagnosed with high blood pressure. The medicine I was prescribed for high blood pressure was subsequently found to cause coronary calcification. So for my shingles I was given gabapentin, which likely caused neuropathy and inflammation, which caused high blood pressure. The blood pressure medication caused calcification in my circulatory system, which likely triggered my type 2 diabetes. I was prescribed a. Increasing amount of metformin for the diabetes. Within a year of metformin exposure, I began having neuropathy in my feet. I was prescribed an increasing amount of gabapentin to deal with the neuropathy. It took less than six months of metformin and gabapentin to lose nerve sensitivity in my feet. Along with the lost nerve sensations in my feet, I also began developing skin ulcers on my ankle that don't heal. For example, in the last week of December 2021, an ulcer wound formed on my right ankle, which persisted until the second week of October 2022. I was taking metformin and gabapentin during that time.
    The wound care doctor that was treating the wound got upset with me because the wound was not healing. He told me that he was going to have me fitted for a prosthetic foot because amputation was warranted if the wound continued in its static state of being. His point was valid, because I could have contracted gangrene at any time. Faced with the prognosis of an impending amputation, I decided to research antiseptics. More specifically, I was interested in what antiseptics would be used in the context of an amputation procedure. To my surprise, the answer was Acetone.
    My ankle got to the point where the agony was all consuming. I had a can of Acetone, and a machete. I had to do something. The machete was out of the question. There's just no way I would give up my foot unless it definitely had gangrene. So that left me with the Acetone. I soaked a cotton cloth with Acetone and applied it all around the wound. It hurt pretty bad, but not more than the wound. So I decided I needed to drown the wound in Acetone. I filled the wound, and experienced a burning sensation that almost rendered me unconcious. The burning actually went away pretty quick. I filled the wound again, and kept adding drops of acetone as it evaporated and absorbed. Within a minute, some bubbles came up from the bottom of the wound. I applied pressure, put bandages on, and within ten days, the wound was completely healed. Since then, any time I have a mosquito bite, or any skin abrasion, I soak a cotton ball with acetone, hold it on the wound or bite, and by the next day the wound or bite will have completely healed. I am not a doctor, so please dont take my personal testimony as medical advice. The issue relates to all of these secrets that the medical industry holds as a matter of protecting their income. Acetone should be the go to antiseptic solution in our drug stores. We shouldn't be going to the paint section of a home improvement store to get the best antiseptic for treating minor skin wounds. Acetone has a danger aspect I hadn't known until I was researching it. Acetone is the most addictive liquid to drink in the world. It took desperation for me to pour acetone on a wound, but I still have my right foot. I don't know what possesses one to drink Acetone, but apparently just one taste of it results in a fatal addiction lasting less than three months.
    It wasn't until this year that i was finally allowed to stop metformin, as Gardiance was available as a generic, so it was covered by insurance. I had quite the gabapentin in 2021. It was also in 2021 that the coronary calcification was found to be preventing a valve in the left atrium from closing. The condition was an inoperable time bomb. That's when I researched ways to treat coronary calcification and found out about Berberine through the video this thread links to. My heart was checked via uktrasound in August of this year. There were no signs of any coronary calcification.
    I have been off of metformin for four months now. Very slowly, I am noticing a return of sensation to the skin on my feet. I also notice that neuropathy ebbs and flows with sugar levels. No spikes in sugar , no spikes in pain. The spikes can go in either direction to the same effect. Therefore the focus is on learning where the balance is for our bodies, and helping our body maintain that balance. Part of doing that is not having to chronically take medications like metformin, gabapentin, and hypertension medications which may make some numbers on a report look better, but ultimately prove to be cures that create more disease. It's all about making money to feed the illustrious hospital profit machine. For those who just became unglued from what I wrote in that last sentence, I never signed an NDA. The truth is the truth, and our medical industry needs to stop their practice of keeping secrets as a means of protecting revenue. Cancer was cured in 2016. Yet last year my sister was diagnosed with breast cancer, and received traditional surgery and chemotherapy. In the same month she was diagnosed, I had a routine physical which found at least 13 skin cancer lesions spanning from the top of my head to my lower extremeties. I treated myself for the skin cancer by taking a course of Fenbendazol, one pill per day for four days, three days no pill, repeat for 90 days. The skin cancer diagnosis was made in October 2022. My first appointment with a skin cancer specialist was in the last week of January 2023. The shock and disbelief on the face of the specialist was priceless, as every lesion had been photographically documented, and none of the lesions were found active. Instead, I have white spots now where the cancer had started.
    My sister refused to even consider the treatment I took because she trusted her doctor. She didn't lose her spouse to cancer. I did. Because she didn't, and still won't avail herself of the cure (because Im the little brother, so what do I know,.right). Sadly this means that at some point the cancer she had will metastasize, or the chemo they administered to her will cause a new form of treatment resistant cancer. She's essentially on an assembly line for the medical industry's income, when she could have taken the course of Fenben for less than $100, and she would be cancer free.
    I do apologize for going on such a long tangent here, which really wasnt warranted by the simple question. But I saw the word metformin, and that got me going to where I had to spill these beans.
    There's so much to say about all of this, I am planning to start a youtube channel to help spread the word and hopefully make a difference in this world for all the people that are needlessly suffering, simply because they trust their doctor to do what's best for them. The doctors do what is best for their practice, so they can support themselves. Patients are just the inventory doctors use to make their money. It's really that simple. I believe that there is always a need for doctors, even if a lot of their hidden tricks of the trade are common knowledge, doctors will always have plenty of work, and they deserve a handsome reward for the differences they do make in many lives. But please, stop taking metformin and insist on a replacement med like gardiance.
    Cheers

    • @glenliesegang233
      @glenliesegang233 9 місяців тому +7

      Metfotmin blocks B12 absorption. If you get peripheral neuropathy GET A B12 LEVEL (even better, an RBC B12 level. ) If 800.

    • @PattiKeefer
      @PattiKeefer 8 місяців тому +2

      God bless you for sharing your experience. I pray you are well. You are brave not foolish. It's so difficult to separate truth from lies these days. Sometimes the stress of trying to do that is more detrimental to our health than anything else.

    • @The_10th_Man
      @The_10th_Man 7 місяців тому +3

      Is this the power of AI ?

    • @darrenclarke4671
      @darrenclarke4671 5 місяців тому +1

      O just finished reading your story, and I have to add that I have a very similar story! Foot infections, neuropathy, type2 diabetes, gabapentin, metformin, etc, etc. I suffered with what was diagnosed as neuropathy, years before becoming TYPE2 diabetic, and every doctor blamed it on sugar. I always knew they were wrong but it took more about 15 years of looking for answers to realize that I wasn't wrong. The prescription medication I was continually being prescribed caused so much damage and pain to my body, but starting in September 2019, after 3 months of researching veganism and going vegan for 2 years, I was able to get off of all of the 16 pills per day I was taking, plus the pain meds. None of my doctors seemed to be happy with me getting healthy, except for 1. I do a vegan diet 4 - 5 days per week, and allow myself to eat meat the other days, and I feel great. I still have some tingling and numbness in my feet, but it's not bringing me to tears anymore and I Don need pain meds at all.
      You're correct with all that you said above. Blessings to you! We have to wake people up! The food in America so many eat is making us sick, and the medication doesn't really heal anything, in the long term, especially.

    • @alisonbamford6723
      @alisonbamford6723 5 місяців тому +3

      I reversed my neuropathy 16 years ago by dumping highly refined wheat & sugar & adopting a whole food diet with supplements including magnesium, B1 & ‘Active’ B12.

  • @PileofKyle
    @PileofKyle Рік тому +17

    Allicin found in garlic also lowers TMAO.

    • @zzzxxzzz3248
      @zzzxxzzz3248 9 місяців тому

      Dihydroberberine is much better than berberine .

  • @Ellifiknow
    @Ellifiknow 6 місяців тому +20

    My opinions are as follows... Bernerine is usually taken twice a day before meals, similar to Metformin, at doses of 400 to 500 mg. Prohealth Longevity and Swanson sell it online. Swanson berberine is about half the price of Pro-health Longevity berberine. Bernerine has a very distinctive taste, and it tastes incredibly bad so you want to get it in capsules. Consumer Labs tests a lot of supplements and Swanson is often highly rated. For some reason they don't test Prohealth Longevity as of yet.

  • @georgeloveday9674
    @georgeloveday9674 9 місяців тому +8

    Thanks for the info, but I truly love your sense of humor.

  • @DCGreenZone
    @DCGreenZone Рік тому +17

    Best look into Nattokinase, Lumbrokinase and Serrapeptase if certain unmentionable health challenges have you in a fit.

    • @incognitotorpedo42
      @incognitotorpedo42 Рік тому +3

      What health challenges are "unmentionable"? Covid? If so, it's hardly "unmentionable".

    • @DCGreenZone
      @DCGreenZone Рік тому

      @@incognitotorpedo42 I gave you a link at the NIH regarding Nattokinase and Cardiovascular health... it was immediately removed. You can find it with little effort. Oops, screen refresh and it's there.

    • @xXaustinxX3
      @xXaustinxX3 11 місяців тому +4

      I take all 3

  • @candyrosepetals
    @candyrosepetals Рік тому +5

    Love Berberine and Myo and D-Chiro Inositol for metabolic balance!

  • @whobdis77
    @whobdis77 Рік тому +34

    Great stuff as always. I've been taking Berberine for about a year and it seems to help me keep my weight down and blood sugar in check. I've had some stents in the past so if this helps in that area all the better. I would think just keeping sugar in check and weight down helps with the heart in itself.

    • @Nivloc317
      @Nivloc317 Рік тому +25

      I too have had two stents put in, and I was on a statin for a year post implant. I started having adverse effects from the statin (diarrhea, a known side effect) so I decided to try Berberine. I told my doc what I was doing, and asked to monitor my blood work to see what the net effect was going to be on it. My cholesterol is lower on Berberine, and my APOA1 markers are better than they have been in years. And the diarrhea is gone. I see no down side to taking Berberine other than the price. Statins, covered by insurance only cost me $3 dollars a month. The Berberine is about $30 a month. WORTH IT!

    • @toyman70
      @toyman70 Рік тому

      how much you take a day and milligrams? thanks @@Nivloc317

    • @theancientsancients1769
      @theancientsancients1769 Рік тому

      ​@@Nivloc317My dad took both Metformin and Berberine. Metformin affected his kidneys negatively and his blood markers for cholesterol and liver were not great . With Berberine his cholesterol levels went down and his liver markers improved and his kidneys too

    • @roba.8907
      @roba.8907 Рік тому

      @@Nivloc317I’m glad to hear you’re doing well after your stents and that Berberine is improving your blood work! I recommend most of my cardiac patients also consider taking Magnesium Glycinate and vitamin D3 + K2 supplement as they will further reduce your risk of another cardiac event.

    • @kimkenny556
      @kimkenny556 11 місяців тому

      Research Barbara O’Neill she suggests 1/4 teaspoon of cayenne pepper daily to naturally thin the blood

  • @Burnrate
    @Burnrate Рік тому +30

    It's really cool that the youtube analytics show the percent of hamsters viewing along with all the other info.

  • @dlg5485
    @dlg5485 Рік тому +19

    I started taking berberine about a year ago to help improve blood sugar management and gut health and it has definitely helped with both. My A1C dropped from 5.8 to 5.5 and my gut is functioning much better. I've never had my arterial calcium score tested, but my vascular health (BP, lipid profile, etc) are excellent so I'm not too concerned about plaque. In any case, I do recommend 500mg berberine daily for prevention, but be sure to choose a reputable brand that is 3rd party lab tested for potency and purity.

    • @OnyxOnyx-r7w
      @OnyxOnyx-r7w Рік тому +3

      @dlg5485 Thank you for your contribution; which brand did you use, please? Did you combine it with silymarine to improve berberine bioavailability?

    • @marknasia5293
      @marknasia5293 Рік тому

      @@OnyxOnyx-r7wi shifted to liposomal berberine and it made a noticeable difference.

    • @incognitotorpedo42
      @incognitotorpedo42 Рік тому

      @@OnyxOnyx-r7w How does silymarin improve the bioavailability of berberine? I'm not aware of a bioavailability problem with berberine.

    • @dlg5485
      @dlg5485 Рік тому

      @@OnyxOnyx-r7w My preferred is Douglas Labs Berberine Balance, but it has been out of stock everywhere for several months and each time I ask them about it they say it'll be back soon. I switched to Thorne Berberine which is a fine product, but I prefer Douglas Labs. Hopefully it will be back in stock soon.

    • @DF-de8ib
      @DF-de8ib Рік тому +4

      What brand you using?

  • @Violet-NYC
    @Violet-NYC Рік тому +16

    Excellent video; love your humor! 💠

  • @theprofessor8517
    @theprofessor8517 11 місяців тому +3

    3.2% is in some studies a margin of error. I'm not sold. If it helps other items such as A1C I'd stick to that vs. relying on it reacting to a biome component that could wildly vary in people.

  • @nicoeffem3483
    @nicoeffem3483 9 місяців тому +3

    Thank you sir. Could you mention other effects of Berberine more deeply...including dosage etc. Cheers

  • @erikjanse3994
    @erikjanse3994 Рік тому +50

    My understanding is as follows: It is mainly the soft plaque that may lead to a heart attack (when it erupts into the bloodstream causing a clot), the "hard" plaque which is illustrated in the diagram as plaque (I assume it are the calcium deposits in the artery that lightens up on the diagram and give an indication of the amount of hard plaque) is stable and does nearly not lead to a hart attack. Further my understanding is that statins have a mechanism to convert soft plaque into hard plaque. In other words, when using a statin the amount of (hard) plaque as measured via the calcium deposits may even increase and the amount of soft plaque will decrease, i.e. the risk of a heart attack will also decrease. So only measuring hard plaque does not tell us a lot about the risk of getting a heart attack...... Something to consider???

    • @RichardHarlos
      @RichardHarlos Рік тому +16

      I'm certainly no doctor but from what I think I understand, the soft plaque eruption is a consequence of increased inflammation at the site. If this is so, then protocols for reducing inflammation are also something to consider. With this in mind, I've been taking serrapeptatse and nattokinase enzymes on an empty stomach first thing in the morning, waiting an hour and then eating as usual. Berberine seemed to be recommended immediately before, or midway through, a meal, and also many people recommended taking it with milk thistle, so that's how I take it: berbering & milk thistle, usually midway through my midday meal.
      I have no data or scores to share, but in case you found any of this 'food for thought', I shared. Cheers!

    • @TheRoadhammer379
      @TheRoadhammer379 Рік тому +29

      I just recently survived a 100% blockage of the left ventricle, hard plaque causes the constriction in the artery, soft plaque dislodging log jams against the hard calcified plaque and you are suffering a heart attack. Neither plaque is good, and calcified plaque causes angina.

    • @utubeape
      @utubeape Рік тому +2

      @@TheRoadhammer379 what do you think caused the buildup of the calcim in your arteries?

    • @jimk59
      @jimk59 Рік тому

      Not aware of any reputable study showing statins harden calcium. Sounds like big pharma marketing.

    • @KAT-dg6el
      @KAT-dg6el Рік тому +5

      @@utubeape Inflammation

  • @CTompkins496
    @CTompkins496 Рік тому +66

    I would be curious about the relative effects of Berberine versus Metformin since they are comparable in many ways. If there was some plaque removal effect of Metformin it is surprising that such studies have not been undertaken.

    • @marknasia5293
      @marknasia5293 Рік тому +14

      metformin is very affordable where i live in Asia and you can get it without prescription, no money in studying that, but that is me being skeptical of the pharmaceutical industry

    • @orthotron
      @orthotron Рік тому +4

      @@marknasia5293 industry doesn't fund all the studies, there's also public funding and other sources as well. Govt should prioritize funding studies that the industry doesn't have an incentive to. Maybe they already do

    • @OceanFrontVilla3
      @OceanFrontVilla3 Рік тому +14

      Well given the amount of campaign donations from Pharma, don't expect government to be funding such studies anytime soon!!

    • @tarkovtxusa6626
      @tarkovtxusa6626 Рік тому +3

      There are animal studies and there was an observational study showing fewer vulnerable plaques in those receiving metformin. I scanned the papers quickly but there is data and I read your comment before watching this video.

    • @orthotron
      @orthotron Рік тому

      @@OceanFrontVilla3 yeah, the world is not as simple or screwed up as you think. I'm currently working on a research project funded by the govt (not in the medical field), that's not at all in corporate interests, even though they make huge campaign donations too. And so are many other people I know.

  • @chrisclinton8949
    @chrisclinton8949 6 місяців тому +3

    I started taking berberine…made me nauseous a couple of hours later, but nausea didn’t last more than 15 minutes or so. More concerning is that it made me feel very lightheaded & faint, & that didn’t last very long either. However, those side effects were uncomfortable enough that I quit taking it.

  • @kiwihame
    @kiwihame Рік тому +48

    How are professional researchers still not able to produce robust, high quality studies? Boggles my mind.

    • @ATHLETE.X
      @ATHLETE.X Рік тому +19

      Funding

    • @dabig_guy2204
      @dabig_guy2204 11 місяців тому

      I think you are missing a key factor..They can and are able to produce the most sophisticated research but that would greatly reduce their profits from all the drugs they push down on people. Big pharma is the second largest industry after the industrial-military complex, and we are talking of hundreds of billions of dollars.

    • @donnachristman2528
      @donnachristman2528 11 місяців тому +5

      Yes. It all depends on who’s paying for “research”.

    • @carnivorechronicles
      @carnivorechronicles 11 місяців тому

      Companies and the US government can not rape billions from natural compounds such as berberine and thus no monies for research.

    • @aliciaheisey5194
      @aliciaheisey5194 10 місяців тому

      Because they don’t want to know the truth… big Pharma would take a hit and then pockets wouldn’t be filled.

  • @danieldmg
    @danieldmg Рік тому +13

    I take it, for blood sugar lowering. I had 8,5 a1C and now, for more than 4 months, 5,5 .....for heart, I take also krill oil, good quality fish oil, and garlic oil. I had no previous heart problems, but these measures (plus daily gym) ensurem my last cardio exams were 100% OK

    • @danieldmg
      @danieldmg Рік тому +2

      @@mrcadoia 1500mg/day divided in 2 pills.

    • @danieldmg
      @danieldmg Рік тому +1

      By the way: I started with 2 pills/day (each 500mg) of metformin. Three months after my 'food protocol' I had an appointment with my endocrinologist doctor, and the a1C was already 5,4 and she reduced the metformin to 1 pill/day. Four months later (now) my a1C is 5.5 (lower than the 'normal' limit = 5.7) so I hope she will eliminate the use of metformin, and make a new blood test in 3 months (my appointment is next Wednesday).

    • @danieldmg
      @danieldmg Рік тому

      @@mrcadoia I take both. Metformin prescribed by the doctor, and berberine as a result of my research.

    • @theancientsancients1769
      @theancientsancients1769 Рік тому +1

      ​@@danieldmgMy dad took both Metformin and Berberine. Metformin affected his kidneys negatively and his blood markers for cholesterol and liver were not great . With Berberine his cholesterol levels went down and his liver markers improved and his kidneys too

  • @humblecourageous3919
    @humblecourageous3919 6 місяців тому +8

    I am my own guinea pig. I didn't think I needed statins as the doctor did. I got a CAC scan (coronary artery calcium). My score was 107. For two years I took statins and then got another CAC scan. It had gone up to 193 even with 117 cholesterol. I stopped the statins and just kept with my 50 year vegetarian diet and added K2, D3, magnesium. In two years it went down to 164 even with cholesterol around 235. But the doctors wanted to see low cholesterol. I found that lecithin would reduce cholesterol. So I took it for two more years and my cholesterol was about 199. But the arterial plaque score went UP to 293! Why? Lecithin has choline which increases your TMAO. I'm one year beyond that into only K2, D3, magnesium. I'll see if it goes down again as it had before. Seems like when I personally lower cholesterol, the plaque in my arteries increases. (I have no physical symptoms of heart problems. I think people with 1,500 and 2,000 CAC scores are getting the bypass surgery.)

    • @marcierenee15
      @marcierenee15 3 місяці тому

      Cholesterol gets a bad name- I'm assuming because they have drugs to push.

    • @paulhailey2537
      @paulhailey2537 Місяць тому

      A CAC SCORE has absolutely nothing to do with The Actual Artery being Clogged. You can have a CAC SCORE OF TEN THOUSAND and still have Clear Arteries

  • @alex_candoit
    @alex_candoit Рік тому +20

    Great video as always! Love the editing as well. Good job!

  • @ericmaclaurin8525
    @ericmaclaurin8525 Рік тому +16

    I love those diagrams! It's so much easier than reading words that describe those actions.

  • @GallivantingGrandma
    @GallivantingGrandma Рік тому

    Very informative, concise and helpful! I appreciate your style, thank you!

  • @blanerobertson6515
    @blanerobertson6515 Рік тому +8

    Does the study address whether this is impacting soft plaque, hard plaque, or both?

  • @stevec3526
    @stevec3526 11 місяців тому +18

    Just had a coronary calcium scan of the heart, and a carotid ultrasound of my neck. The calcium score for both my wife and I was zero. We eat a mostly Japanese diet. My A1c is 5.2 and my wife's is 5.3. I am 69, and the wife is 62.

    • @samatoid
      @samatoid 10 місяців тому

      I wonder if cannibals who eat a Japanese diet are very healthy?

    • @lpg12338
      @lpg12338 6 місяців тому +1

      Congratulations! 👍

    • @229glock
      @229glock 2 місяці тому +2

      Totally relevant to the video.

  • @donnamelcher7978
    @donnamelcher7978 9 місяців тому +3

    💓 great information !

  • @davenockels5028
    @davenockels5028 Рік тому +22

    The “TMAO causes CVD” hypothesis needs to address the fact that fish consumption. (Which is VERY high in TMAO) is associated with lower risk of CVD

    • @mjs28s
      @mjs28s Рік тому +6

      Depends on the fish that you are eating and where they are from.
      You can't just look at all fish as "fish".
      The further up the food chain the more compounds (mercury and other industrial pollutants) bioaccumulate.
      Fish lower down in the food chain have less of the other garbage that you don't want in your diet that is in higher concentrations in fish like tuna, sword fish, etc.
      Fish, wild not farmed, are also high in some healthy compounds. Cold water fish, for example, are high in healthy lipids (omega-3, etc). The lower down the food chain the more plants that the fish are eating rather than other fish so less you are getting your low in the food chain fish from polluted waters, they are not giving you as much of a dose of chemicals from industry and farming as higher level fish / predatory fish.
      The lower on the food-chain fish might have enough omega-3s to offset some of the damage brought on by the TMAO.
      "Fish" is a very broad term. It would be like saying food from fast food places is bad for you. Well, if you get a salad with the vinaigrette or baked potato from Wendy's or you build a salad bowl at Chipotle out of the veggie options and leave out the meat and cheese you can easily make for a much healthier meal than if you just averaged every meal combination together to figure out the health benefiting or detrimental impacts of "fast food". Just the beverage choice makes a huge difference. You getting soda? A 12 ounce soda or the 32 ounce soda? Maybe you get water or unsweetened tea.

    • @scottyoung4126
      @scottyoung4126 Рік тому +6

      @@mjs28s The assumption that TMAO is delivering damage, which you state, is perhaps an overstatement of some slivers of evidence.. for some. The other person was trying to say: on paper, in the way nutritional epidemiology assesses these broad dietary impacts, the pescatarians are the only people living longer, when compared to vegetarian and vegan or everybody else. As well, many fish contain high quantities of TMAO, much of which is delivered to the human eater almost directly. Meat eater is a broad term; Fish eater is a broad term; Vegetarian is a broad term. We'll have to imagine that Pescatarians are eating Fish of several shapes and sizes.

    • @davenockels5028
      @davenockels5028 Рік тому +1

      @@mjs28s The heavy metal content of fish has nothing to do with TMAO, unless you know differently………

    • @arihaviv8510
      @arihaviv8510 8 місяців тому

      Farmed fish is much lower in heavy metals than wild (not to mention parasites which is why you should never eat raw wild fish)..plus since they are fed a plant based diet, won't have the issues of cumulative toxins putting them down the food chain

  • @rosemensah5959
    @rosemensah5959 10 місяців тому +4

    Can you do one on nattokinaise ? Also, does fasting shrink the plaque ?

  • @copisetic1104
    @copisetic1104 Рік тому +3

    Dr. James Robert’s did three two hour lectures on UA-cam just on Berberine and it’s effect on human systems.

  • @joerockhead7246
    @joerockhead7246 Рік тому +5

    Thank you.

  • @tiwidub8809
    @tiwidub8809 9 місяців тому +2

    Great info as usual. Thanks a lot. It helps. You're good, man. ❤

  • @mrfoodarama
    @mrfoodarama Рік тому +20

    Leaf Blowers at 8am on a weekend morning = rage inducing 🤣

    • @jonathonpotts5666
      @jonathonpotts5666 Рік тому +2

      my friend is a landscaper he has an electric leaf blower, it is silent there is no excuse

    • @danmarjenka6361
      @danmarjenka6361 Рік тому

      Someday, almost everything will be electric. The world will then be quieter and people's blood pressure will be lower.

    • @markbajek2541
      @markbajek2541 2 місяці тому

      My grass tends to be too wet to cut at 8 AM, otherwise I think my city allows a 6 AM start time.

  • @tas1624
    @tas1624 9 місяців тому +1

    Why would anyone expect plaque to decrease in size based on mechanism of decreased TMAO formation? Assuming TMAO is a oxidant from its description and oxidize LDL is the necessary initiator of plaque formation then expected result should be a decrease in plaque growth.

  • @johnmacmac7550
    @johnmacmac7550 5 місяців тому +1

    I'm wondering if the effects of dihydraberberine would be better?

  • @stacyvie
    @stacyvie Рік тому +7

    Interested in knowing how the plaque buildup was lessened. Was it dissolved or dislodged?

  • @bryanstanley4295
    @bryanstanley4295 11 місяців тому +8

    Exercise, grounding, and avoiding sugar and excess carbs can prevent and even reduce plaque size. Its all about reducing and preventing inflammation

    • @xiamengbaby
      @xiamengbaby 8 місяців тому

      What is grounding?

    • @louismartin9546
      @louismartin9546 6 місяців тому +3

      ​@@xiamengbabyno footwear. Going barefoot while doing outdoor activities. Not on concrete, asphalt pavement. Soil and grass only

    • @mikemcmullen5637
      @mikemcmullen5637 Місяць тому +1

      @@xiamengbaby It helps in lowering blood viscosity, by going barefoot one absorbs ions from the earth...

  • @blueprint7000
    @blueprint7000 Рік тому +7

    What about K2 mk7 vitamin ? I heard it also helps

    • @Shiv1971
      @Shiv1971 9 місяців тому

      2 MG a day for a month, I used to take 20 liposomal pills (without choking on them) in about a minute. Also small doses 180mcg when taking calcium helps. 9 mg a day boron also works well with bones.

  • @billkemp9315
    @billkemp9315 Рік тому +24

    Are there any studies done combining Berberine, Nattokinase, and K2 for plaque?

    • @MrKanti-yy5ux
      @MrKanti-yy5ux Рік тому +2

      Almost certainly not, but I can't see the harm in it for prevention.

    • @safedba
      @safedba Рік тому +18

      I found one, though it's behind a paywall. Park, H. J., Choi, M. S., & Lee, W. S. (2015). Combination of berberine, nattokinase and vitamin K2 effectively reduces atherosclerotic plaque formation in apolipoprotein E-deficient mice. Phytotherapy Research, 29(8), 1373-1378.

    • @theancientsancients1769
      @theancientsancients1769 Рік тому

      ​@@MrKanti-yy5uxCX8 by Xtend-life targets arterial plaque and it has these ingredients and more

    • @lisalapoint7022
      @lisalapoint7022 11 місяців тому +1

      ​@@safedba❤

    • @satxsatxsatx
      @satxsatxsatx 9 місяців тому

      I'm taking that combination.
      Of course I have no idea as usual whether it's doing any good.😂

  • @jbayne7761
    @jbayne7761 Рік тому +2

    Question. I have read mix human studies where transplant patients have used berberine.
    Can you do a video on transplant drugs berberine? From what i can tell berberine increases the strength of the meds.

  • @josephabdilla1383
    @josephabdilla1383 Рік тому +5

    Awesome breakdown! Thanks

  • @jstevenson21567
    @jstevenson21567 8 місяців тому +2

    If I currently supplement with magnesium and nattokinase, would it be safe for me to also take berberine? I am not on any medications. I am just concerned that all three of these supplements can thin blood.

  • @Asiansxsymbol
    @Asiansxsymbol 5 місяців тому

    Molly is a good source of reducing many illnesses. It makes me dance all night long, which is a very effective aerobic exercise. 😊

  • @DM-jt4rh
    @DM-jt4rh 8 місяців тому +4

    Are you saying that 1% of humans are actually HAMPSTERS!?!?

  • @danielwalker4056
    @danielwalker4056 Рік тому +6

    How much berberine is suggested.per day ?

    • @lorah2087
      @lorah2087 7 місяців тому

      One of tge main studies recomends 500mg one half hour before meals 3x a day but that was for regulating blood sugar levels.

  • @jennygibbons1258
    @jennygibbons1258 5 місяців тому

    Thanks so much for your balanced information.

  • @katkalucky4060
    @katkalucky4060 8 місяців тому +1

    Thanks for your informative videos

  • @EV-wp1fj
    @EV-wp1fj Рік тому +3

    Some of this suggests L-Carnitine supplementation or anything that increases TMA / TMAO might promote arteriosclerosis? Help me out here.

  • @RG-yz8ov
    @RG-yz8ov 3 місяці тому +2

    Can you go over nattokinase for this

  • @DCGreenZone
    @DCGreenZone Рік тому +5

    Maybe the reduction in insulin resistance plays a part as well.
    >>Multiple studies have demonstrated that insulin resistance is a strong predictor of atherosclerotic cardiovascular (CV) disease (ASCVD) (1-11) and have been summarized in a recent meta-analysis by Gast et al. (12).

  • @tonypolistina3357
    @tonypolistina3357 9 місяців тому +2

    Is there any recomended places to buy this supplement that is good quality?
    Or combined with other helpfull sups such as cinnamon ect?

    • @katiedid1851
      @katiedid1851 8 місяців тому +1

      Do you have a natural food co op or health food store in your area? Or nearby?

    • @lpg12338
      @lpg12338 6 місяців тому +1

      Check out Thorne supplements.

  • @granthuxham2491
    @granthuxham2491 Рік тому +2

    Thank you for posting this - fascinating and enlightening.

  • @EVentures888
    @EVentures888 24 дні тому

    What was the daily dosage of Berberine administered in the studies?

  • @dabig_guy2204
    @dabig_guy2204 11 місяців тому +2

    Amazing information and the video.

  • @carolj.3175
    @carolj.3175 Рік тому +1

    OMG my dr is having fits my CAC was 70 and TC is 277. Wants me on Statins yesterday. I'm 66 my HDL is 78. Only thing concerning me is TG too high.

    • @blanerobertson6515
      @blanerobertson6515 Рік тому +2

      Cut out ALL refined carbs (they're everywhere if you eat anything froma box from the grocery store) for a few weeks, then check your TGs again. If still high, look to cut any other carb sources (fruits for example).

  • @MichaelMerritt
    @MichaelMerritt Рік тому +3

    I wish I could take berberine without intense gerd as a side effect. With or without/o food doesn’t seem to help much. Seems like a great natural option.

    • @cynthiam1381
      @cynthiam1381 11 місяців тому

      Try taking it at bedtime

    • @MichaelMerritt
      @MichaelMerritt 11 місяців тому

      @@cynthiam1381 that’s when I was mostly taking it. I wake up all night with acid in my throat.

    • @maryannnargang8109
      @maryannnargang8109 2 місяці тому +1

      I’ve had customers switch from the dried berberine herb to Lipomicel form because of nausea and stomach upset with great results.

  • @aperson1181
    @aperson1181 11 місяців тому +4

    What were the amounts of Barberine used in the studies?

  • @elizabethpears307
    @elizabethpears307 6 місяців тому +1

    Look at amla studies. Carotid imaging showed a small plaque. I started taking Amla in liquid form and the next year that plaque was gone.

    • @samia6888
      @samia6888 2 місяці тому

      How much amla did you take?

  • @Nando_lifts2021
    @Nando_lifts2021 Місяць тому

    Is it unsafe to take phosphotylcholine supplements for liver?

  • @FunJayJay
    @FunJayJay 3 місяці тому +1

    Wait .. does that mean if I take choline and l-carnitine supplements,
    TMA will increase the
    and that will increase the plaque in my arteries?
    Is that correct?
    Now I am too worried

  • @andyrwebman
    @andyrwebman 8 місяців тому +1

    Nice to know. I've already ben taking Berberine to help my arrhythmia (it's pretty effective)

  • @wakeupthebear
    @wakeupthebear 6 місяців тому

    Love the diagram?
    This was interesting.
    Thank you!

  • @LagMasterSam
    @LagMasterSam Місяць тому

    I tried taking Berberine as an appetite suppressant. It did work for that, but the side effects were too much for me...
    - I was constantly ultra thirsty.
    - When I would take a shower or apply lotion or sunscreen, a really sour odor would come off my skin.
    - It amplified the effect of my beta blocker too much. My heart rate would refuse to go above 127 when working out, even if I was huffing and puffing like crazy. I tried not taking the beta blocker and just taking berberine, but that didn't work.

  • @edelmary1131
    @edelmary1131 Рік тому

    nattokinease really works...i got rid of a 8 yera blood clot in 3 weeks with it...amazed

  • @inachu
    @inachu Рік тому +1

    I take it for a while and I love it!

  • @danielmcshane6502
    @danielmcshane6502 Рік тому +2

    I had a bad reaction to berberine, vomiting for 2 days, couldn’t keep food or water down. I’ve never spewed so much in my life.

  • @gabriellew6467
    @gabriellew6467 Рік тому +2

    Highly interesting facts served with a dose of chuckles - thank you

  • @gbensen8069
    @gbensen8069 Місяць тому

    Any input on taking berberine and nattokinaise after heart valve replacement?

  • @wheelofcheese100
    @wheelofcheese100 Рік тому +7

    I’ve heard this once before and kinda blew it off but hearing again from you is shocking (in a good way).

  • @thesystemera
    @thesystemera 10 місяців тому +3

    Damn i love your humor man!

  • @josearieltrinidad7734
    @josearieltrinidad7734 Місяць тому

    Berberine is typically used in Vietnam to treat stomach disorders.

  • @MeesterJ
    @MeesterJ Рік тому +3

    Choline is essential for methylation and so good for a lot of things. Why does it turn into Tmao?😮 makes no sense

  • @wread1982
    @wread1982 10 місяців тому +1

    My LDL went up after a year on Berberine and it gave me anxiety and palpitations, it all went away when I stopped, I don’t have any side effects of Crestor

  • @nicolabenson1155
    @nicolabenson1155 Рік тому +2

    Rather than taking Berberine, would it not be easier to reduce dietary choline to reduce TMAO in circulation?

  • @tkinnc1
    @tkinnc1 10 місяців тому +1

    Maybe it's role is more preventative than restorative.

  • @elibennett6168
    @elibennett6168 Рік тому +8

    Spouse had an A1C of 6.1 and started taking berberine about six weeks before next A1C and it came down to 5.9 (listed as high normal from prediabetic at this particular reference lab). Obviously we don't know if it was the berberine but it was the main change. Could it's affect on carbs be of the plaque lowering capacity?

    • @N330AA
      @N330AA Рік тому +2

      That change is within margin of error FYI. Though Berberine does seem to have a positive effect anyway.

  • @plakeway2588
    @plakeway2588 9 місяців тому

    Which berberine product do you recommend?

  • @salleone6387
    @salleone6387 7 місяців тому +1

    Is it worth switching to Dihydroberberine?

  • @DEValentine
    @DEValentine 11 місяців тому +2

    What dosage of berberine did the study subjects receive?

  • @MichaelAmen316
    @MichaelAmen316 8 місяців тому +1

    Does dihydroberberine do this as well??

  • @kevinmccue1005
    @kevinmccue1005 2 місяці тому +1

    What was the dosage and time span?

  • @JamesMcCabe703
    @JamesMcCabe703 Рік тому +1

    @Physionic is there a berberine dosage that was used? if so, can you post it? Currently I take 1200mg per day.

    • @tracymullane8818
      @tracymullane8818 Рік тому +1

      I read 1 study with good statistical outcome that used 500 mg twice a day for a total of 1 g a day.
      This was a study that focused on insulin resistance though not TMAO.

  • @farhat5325
    @farhat5325 Рік тому +5

    Does exercise reduce the arterial plaque ?

  • @samia6888
    @samia6888 2 місяці тому +1

    I just want to know what actually decreases plaque formation. They found a small amount of plaque in my carotid artery and I just want to safely get rid of it.

  • @Anthropic312
    @Anthropic312 11 місяців тому +1

    How many mg berberine?

  • @cosmonaut9942
    @cosmonaut9942 9 місяців тому

    Does metformin shrink plaque or does it prevent the formation of plaque?

  • @jesincov
    @jesincov 11 місяців тому +3

    I took Berberine for a few months after seeing this study. Unfortunately I think I caused an irregular heartbeat

    • @shanti888
      @shanti888 6 місяців тому

      That will reverse after stopping within 3-4 weeks usually

  • @tonypolistina3357
    @tonypolistina3357 5 місяців тому +2

    Did you just say Berberine increases the risk of heart disease ?

  • @tobyramsey4692
    @tobyramsey4692 Рік тому +5

    As someone who has the APOE 4,4 gene it has been my experience that choline (and there's a few different molecules) is recommended for the health of certain brain tissues which are "deteriorating". How do I attend to both my heart and brain health?

    • @nicolabenson1155
      @nicolabenson1155 Рік тому +2

      Most things good for our brains are good for our hearts, so if you trying to get your sleep, exercise, social stimulation, reducing stress and moderating alcohol, while eating a lots of fruit, veg, nuts, seeds and beans, some extra choline is probably fine.

    • @tigerspiritjourney
      @tigerspiritjourney Рік тому +3

      High fat, moderate protein!

  • @kriswalter8273
    @kriswalter8273 7 місяців тому

    Thank you , because of you m'y brother IS going to tale berberine, but you forgot to Say that it lowers blood sugar, reduces cellular telomerase etc etc

  • @peterpots74
    @peterpots74 8 місяців тому

    How was Berberine administered? Orally? How much? How long? I have DoTerra Berberine and I think I can ingest it diluted in water. OR, put it on the skin to be absorbed topically?

  • @jrmint2
    @jrmint2 8 місяців тому +1

    what is a good brand of Berberine?

    • @lpg12338
      @lpg12338 6 місяців тому +1

      Check out Thorne supplements.

  • @mmnairkochi
    @mmnairkochi 7 місяців тому

    Are the Berberine benefits also available with Dihydroberberine? I am unable to take berberine due to gastrointestinal side effects, but have been taking Dihydroberberine for 3 years now.