EP 95: Low Dose Naltrexone (LDN) - What When Why How
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- Опубліковано 10 вер 2024
- In this episode, Dr. Shawn Tassone discusses the use of low dose naltrexone (LDN) as a treatment for various conditions, particularly autoimmune diseases. LDN has been shown to reduce symptom severity in conditions like fibromyalgia, Crohn's disease, multiple sclerosis, and chronic pain syndrome. It acts as an anti-inflammatory agent and has neuroprotective effects. Dr. Tassone explains how LDN works, the dosing, and the potential side effects. He also mentions the LDN Research Trust as a resource for more information. LDN is being used in various medical fields, including women's health, and can be prescribed by doctors with a functional or integrated medicine background.
Episode Highlights
- Low dose naltrexone (LDN) has been shown to reduce symptom severity in various conditions, particularly autoimmune diseases.
- LDN acts as an anti-inflammatory agent and has neuroprotective effects.
- The dosing of LDN is much lower than the typical opioid dosage and can vary based on the patient's sensitivity.
- LDN is well-tolerated and has minimal side effects, with the most common being stimulation and vivid dreams.
- LDN is being used in various medical fields, including women's health, and can be prescribed by doctors with a functional or integrated medicine background.
Resources:
Dr. Shawn Tassone's Practice | www.drshawntas...
Dr. Shawn Tassone's Book - The Hormone Balance Bible | tassonemd.com/....
Dr. Shawn Tassone's Integrative Hormonal Archetype Quiz | Tassonemd.com/quiz
Medical Disclaimer
This podcast and website represent the opinions of Dr. Shawn Tassone and his guests. The content here should not be taken as medical advice and is for informational purposes only. Because each person is so unique, please consult your health care professional for any medical questions.
You never offend Dr Tassone.. you are real and have helped and continue to help many women on this crazy menopause journey 🙏❤️
Just a word of caution: a few years back after seeing so many folks raving about LDN I talked with my doc and he prescribed a very low dose, with plans to increase. I had trouble tolerating it but was told that was normal, just keep taking it. But it sent me into Afib, which since that time gave me plenty of trouble, surgery, enlarged heart. I have other issues, including autoimmune and metabolic issues, so the cause probably wasn't all LDN but definitely a factor. I'm just saying, if it's making you feel awful, have a serious talk with your doctor and honor your own intuition.
You would greatly benefit from a low carb diet for both autoimmune + metabolic issues. Unlikely LDN sent you into AF (I work in cardiology, my husband is also an electrophysiologist). Your metabolic issues are likely the primary driver for AF.
What dosage were you taking?
@@xokissmekatexo
Most doctors don't know how much you should take. My doctor started me on too large of a dose and I researched it and found out how to start it. I started on 0.5 mg. and worked up to 4.5 mg. where as my immunologist had started me at 12.5 which is way too much. It comes in a 50 mg. tab and I compound it myself mix it with 50 ml. of distilled water. The large dose made me very ill for an afternoon. Vomiting, brain shocks, etc. I have a heart problem also where my electrical system has partially shut down and I have too high and low heart rhythm. Still in the diagnose stage for that and have an implanted loop recorder to monitor my heart.The danger is AFIB, and I take med for that, and my have to get a pacemaker. Make sure your doctors know about what you are taking and why.
I started LDN April 2, 2011. I take it for my fibromyalgia I did the titration. I started with 1/2 mg worked up to a milligram and then a milligram and a half and so on and so forth until I got to 3.0 That was too much for me so I cut it back to 2.5 and I've been at 2.5 mg for all this time. It's my belief from the day I started it until today that it is an immune modulator. and it's a grassroots because no doctors is going to tell you about it unless they're great like this one
Have you noticed improvements?
@@kjkernSerendipity well yes I wouldn't be taking it once daily for 13 years if I didn't. It is a lifelong treatment and that's what I intend to do.
I don't have vivid dreams anymore but in the beginning I did I wake up thinking that the dream was real that was a trip.
But also I have switched to daytime dosing instead of nighttime dosing some people end up doing that I did that halfway through so maybe like six years ago.
And if you wanna learn a lot about start of Low-dose-naltrexone-aka-LDN you can look up Dr. Bahari on UA-cam he was using 50 mg x3 daily on his alcoholic patients and found out months go by the alcohol patients that had multiple sclerosis were actually feeling better. So he started experimenting with the doses lower and lower and lower till he can get the same effect Without a full 150 mg a day doses.?
3.0 mg Was good dose he landed on.
Few yrs later then one day one of his MS patients who was taking 2.5 accidentally took her medication twice in the a few hours and she said she felt better so he started trying & then prescribing 4.5.
Like I said it doesn't have a lot of studies also no big pharmaceutical rep is going to come in push and LDN at $10 a month
because it's so inexpensive well at least it was when I started buying it it was $10 a month now it's up to $35. Most insurance Doesn't cover it because it's a compound medicine that they have absolutely no clue about. Some people will get prescribed naltrexone and then diluted with distilled water and use a syringe to dose. But the problem that people have been having over the years is ins tagged some as narcotic Abusers if they are prescribed full doses of naltrexone so you see the catch 22 there. That's why I just get it compounded
I started a Facebook group of April 2011 called got endorphins? LDN and it's still up-to-date 22,000 members. But I got so burned out on it I gave it to my admin for the past four years. But it's still going strong. It's not as technical and as rigid as the group that he suggested.
It's been a life saver for my Long Haul covid symptoms.
Than you for talking again on LDN, I'm a nurse and have take to peers, like me, they had no idea about this use an an anti-inflammatory
I use LDN for trigeminal neuralgia. It has taken the edge off the excrutiating pain.
Dr.T.I love your teaching,,you are great !! Can definitely tell you are sensitive to your patient's because you talk in a way females can immediately connect.!❤
Today was a fun and informative episode! Loved it!!!!🤩
I sure am grateful for LDN! Been on it for years at 0.5mg. Take it in the morning on an empty stomach. It has helped my pain and long haul CV as well!
I take LDN, 4 mg. I'm really lucky that I have a GYN here in the greater St. Louis area who prescribed this to me and has a general holistic approach. She also, based on experimenting on herself about 25 years ago, promotes the use of bioidentical hormone pellets, which for her, had an immediate positive result, and so then offered it to her patients. I've been on pellets, estradiol and testosterone since 2002 and have done wonderfully.
I have Hashimotos which is why I'm on LDN. My GYN has also written a couple of books on the importance of testosterone for women.
I've only recently discovered this holistic GYN here, and so appreciate everything I've had a chance to listen to!
Hello, curious who you see in the St. Louis area that Rx's LDN? My niece lives there and is looking for a more holistic doctor. Thank you!
@@cheribeck101Hi there. The Dr. Is Kathy Maupin, MD and her practice has evolved away from regular GYN practice into hormone treatments, etc. It is called BIOBALANCE HEALTH, on Olive Blvd. She employs several well qualified Nurse Practitioners who also administer treatments and prescribe LDN, among others. Hope that helps : )
@@cheribeck101 Hi there. My Dr. is Kathy Maupin, MD. Her practice has evolved away from regular GYN to holistic hormone treatments, etc. It's BIOBALANCE HEALTH, located on Olive Blvd. And she employs several qualified Nurse Practitioners who also administer treatments including prescribing LDN and others. Hope that helps : )
Hello, would you mind sharing the name of your Dr. I the STL area. I have peripheral neuropathy and PCOS, and would like to get another opinion.
I've put in a comment to answer someone's question twice, but it won't show up!
My Dr. in the St. Louis area that handles hormone replacement is Dr. Kathy Maupin, MD. She focuses only on hormones and some other things, but no longer does traditional GYN exams, etc.
Her practice is called BIOBALANCE HEALTH, located on Olive Blvd.
Hope that helps.
My understanding is that fibromyalgia research is starting to lean back the other way again towards a belief that FMS does in fact have an autoimmune component.
LDN is a great topic, thanks for the video!
Doc… many sleep aids also cause disruption like insomnia and vivid dreams etc. back the dose up by 2hrs. In our group of hackers… in the 20% that have these effects, 99% resolved by back it up.
LDN coupled with the healing period of sleep… boom
EMF… phone blockers are BS. We used a high end spectrum analyzer. Earthing sheets have an error in the lead wire… needs to be shielded.
As to my side effect. Bluetooth sets off my tinnitus. Buddy has a tech store. Some days all Bluetooth active and other days none. I recorded the trigger days and then we compared… yup.
Been on LDN 7.5 mg for my UC for about 1 year. It’s been amazing and shocking how well it works. My functional medicine doc suggested it and it’s been great. I used a compounding pharm. My “regular” doc thought my functional medicine doc was a “quack” ..typical. I see my functional meds doc now…yes, it is very activating in the beginning, but about a week or so, that resolves…
All right here I go again anyway as far as the veterinarians black book about LDN for cats they have it completely wrong it's supposed to say .25 mg but the book says 2.5 mg which is what I take I couldn't imagine giving that to a 10 pound cat so make sure you do your research I don't know if they change the book but I'm sure some vets still have the old book about what to do with LDN and Dogs even take it I've seen horses take it
Uh oh 😳 if it helps too well, FDA will block pharmacies from distributing it like they did ivermectin...you know the horse de-wormer...
Interesting comment regarding exercise. I have MS, tried LDN, didn’t really think much about it, can’t say it did anything for me overall but I do feel remarkably better with consistent exercise (biking + yoga).
I compound it myself. It comes in a 50 mg. tab. Mix that with 50 ml. of distilled water and let dissolve. Use a syringe type dropper to measure to 4.5 mg and put in mouth. ( I started out with .5 and worked up to 4.5 gradually.) I've been taking it for almost 10 years. Prescribed by my immunologist.
Do you treat interstitial cystitis? I’m going to make an appointment with you for HRT. I’m 54 and had to have a total hysterectomy at 35 for severe endometriosis.
Quit carbs and those things go away as they are the cause.
Interesting topic
Gol dang it. I missed another live!
@@shelleykapp9637 it was prerecorded
What are your thoughts with using LDN for anxiety & depression?
Narcan is NaLOXone. Not naltrexone. Research the difference
Thank you Dr. T. !!!! How receptive are health insurance providers approving this med? Sorry ,you answered my qs in the video:)
Interesting topic on microdosing. I just watched The Diary of a CEO with someone talking about microdosing Ozempic.
And what happens when you microdose Ozempic?
@@kjkernSerendipity I wouldn’t do that personally
@@ShawnTassoneMDPhD I wouldn't either; fascinating topic, nonetheless.
Oops... you got cut off, Dr. T!
I was wondering
Can it help for type 1 diabetics?
Have you had experience with Lichens Sclerosus as a Gyn MD and autoimmune disease? Steroids are the “Gold Standard” of TX for LS. Steroids don’t do much. Might LDN help with Lichens Sclerosus?
I've been on LDN for over 13 years as of June. And I do belong to some health groups. And I have done so much research on my own problems even though LS is not one of them I have a problem with oxalate, Oxalate Toxicity. And I did see a piece online from the Mayo clinic about oxalate toxicity and LS