OSTEOPOROSIS GAME CHANGER: VITAMIN E & GG w/ Dr. Barrie Tan + BoneCoach™ Osteoporosis & Osteopenia
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- Опубліковано 6 лип 2024
- Fascinating episode for those with osteoporosis on the Power of Vitamin E, Tocotrienols, & GG for bone health.
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-- EPISODE OVERVIEW --
Joining us today to explore Vitamin E, Tocotrienols, and Geranylgeraniol and how these two little known nutrients may hold the key to improving your health and your bones is Dr. Barrie Tan.
-- RESOURCES MENTIONED --
**Find the show notes @ bonecoach.com/drbarrietan-vit...
-- TOPICS COVERED --
0:00 - Episode start
2:24 - Meet our guest, Dr. Barrie Tan
4:03 - Dr. Tan's discovery of the annatto plant and his motivation to study it
7:48 - An introduction to tocotrienols, geranylgeraniol, and their differences
9:48 - Understanding vitamin E and the significance of tocopherol
19:01 - The function of geranylgeraniol
20:53 - Benefits of tocotrienols for osteoporosis and bone health
30:31 - The reason behind Dr. Barrie Tan's specific study
32:17 - Geranylgeraniol's role in MK4 synthesis and its importance for bone health
39:19 - Benefits of MK4: kidney stones, artery calcification, and dementia
41:34 - Discussion on preclinical and animal studies on geranylgeraniol, its effects on bone turnover, stiffness, and its benefits for those on bisphosphonates
47:52 - Overview of 20 clinical studies on tocotrienols and their diverse benefits
57:02 - Summary of key studies and results, specifically focusing on Tocotrienols
1:00:17 - Dr. Tan elaborates on recent studies, insights on statins, and other crucial findings
1:06:35 - Guidance on where to find exact dosages and amounts of discussed nutrients and ingredients
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-- MEDICAL DISCLAIMER --
The information contained within this episode should not be considered medical advice. Always consult with your healthcare team and trained medical professionals before making any medical decisions and changes to your diet, lifestyle, and exercise routine.
-- CLOSING NOTE FROM BONE COACH --
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Kevin
Bone Coach
#osteoporosis #osteopenia #bonehealth #bonecoach #kevinellis #vitamine #womenshealth #healthyaging #boneloss #bonedensity
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In many cultures, we use the Anatto seeds to color foods reddish orange color
Dr Tan is adorable. I love his personality and passion.
Amazing !!! I am in complete awe of Dr Barrie Tan and his research !!! It makes so much sense and this is so inspiring and imperative to wellness!!! Thanks Kevin and please bring Dr Tan back !
Fabulous interview that filled me with so much hope. However, disappointingly your product is not available in Australia. This only says to me your product must really work in improving the health of older people, otherwise our customs would not stop it from entering our country. I have experienced this with other health products that also work to improve the health of people. Thank you for the interview. You both have such great energy and enthusiasm.
Thank you for sharing… glad this interview was helpful! ❤
Right now, this is available in the U.S., UK, and Canada with other countries becoming available in the near future.
If you Search for Healthy Bones Co. Annatrol on Google, you can learn more about these two nutrients we discussed and see the studies we mentioned.
You can also find the product we discussed here.
=> healthybonesco.com/products/annatrol
Hi there. Also from Australia ... have been following Dr Tan's work for the last month or so and have had to source the GG, Tocotrienol, MK4 and CoQ10 separately. Very confusing and frustrating. I hope the Bone Coach will eventually ship to Australia. What I have not been able to find out is what is the best combination of these nutrients - the Tocotrienal +GG in one pill is great, but I'm also taking the MK4 (with 1000mg VitD because I read that D is needed to assist the MK4 get to the bone) but where does CoQ10 best sit? I guess I'll just keep watching Dr Tan's videos to see if he gives that info somewhere. Very exciting to think that these nutrients may help improve a number of conditions, but osteoporosis is my primary goal at the moment.
It's impossible not to like Dr Tan and what a fantastic contribution he has made to our understanding of these important anti-oxidants. He's also helping to make sense of the mechanisms for bone loss and subsequent treatment by taking the supplements we need.
Such excitement :) contagious! Thank you.
Passionate Dr Tan
Thank you lot. I have already of both nutrients.
Who is this cute fella so excited
The very best interview with Dr Tan so far! ❤
Wow this was an incredible interview.
Giving so much hope and clarity to people in this often contradictory and controversial landscape of what to do/take for osteoporosis.
Thank you 🙏
So glad that was helpful, Lisa. Thank you for sharing and supporting! 🙂
If you Search for Healthy Bones Co. Annatrol on Google, you can learn more about these two nutrients we discussed and see the studies we mentioned.
You can also find the product we discussed here.
=> healthybonesco.com/products/annatrol
Love using annatto as food coloring.
Thank you for bringing this podcast to everyone. Wonderful information to have for my severe osteoporosis and for those just beginning a journey of osteopenia or osteoporosis.
Glad it was helpful!
If you Search for Healthy Bones Co. Annatrol on Google, you can learn more about these two nutrients we discussed and see the studies we mentioned.
You can also find the product we discussed here.
=> healthybonesco.com/products/annatrol
Fantastic interview and information! Thank you!
Glad you enjoyed it!
If you Search for Healthy Bones Co. Annatrol on Google, you can learn more about these two nutrients we discussed and see the studies we mentioned.
You can also find the product we discussed here.
=> healthybonesco.com/products/annatrol
Break show. I take vitamin e complex that has Tocotrienols in them. But the GG is new to me. Thanks
Is there available in Canada?
Please Doctor we want to know how i purchase the GG? And others products?
So we need three different vitamins, Vitamin E with Tocotrienols, GG and k4. Do I have that right?
my question is if tocopheral cancels out tocotriebal and that want us to take it with food which is how we get to tocopheral? We would always be canceling it out
This was such a great interview and great information. I found myself smiling several times due to the positive energy. I feel hopeful!
I’ve been taking tocotrienols for several years, but my bones still deteriorated due to undiagnosed Hyperparathyroidism. (I’m thinking maybe the damage would have been much worse if I had not been on it?)
I’m going to watch again later(that’s how good it was😂) and order the additional supplements.
Thanks again, gentlemen!
Really glad you enjoyed this!
Dr. Barrie has researched Vitamin E for over 30 years. He’s the leading expert in this area. 🙂
Search for Healthy Bones Co. Annatrol on Google.
You can also find the product we discussed here.
=> healthybonesco.com/products/annatrol
@@BoneCoach - thank you!
Would GG also help in growing and improving the gums?
Great question!
Multiple studies that show GG can be helpful for oral health and gum health including:
Geranylgeraniol (GG) improving bone in tooth sockets and restoring bone desposition. (1)
GG reduces Bisphosphonate Related Osteonecrosis of the Jaw (BRONJ) Damage including preventing jaw necrosis (2.5x) and preventing gum death (3.5x) (2)
Other studies showed Geranylgeraniol helped seal empty lacunes (extracted sockets) by 45% and improved gum vascularity, osteoblast lining, and epithelial coverage by 67% (3,4)
The benefits for most applications of GG start at around 150mg/day for bone health, oral health, CoQ10 replenishment, muscle tone and balance and go up to 300/mg day for those who have used or are using Statin & Bisphosphonate medications and for myopathy (muscle disorders and weakness) and sarcopenia (age-related progressive loss of muscle mass and strength).**
Healthy Bones Co. Annatrol Bone Support contains 300mg of pure and premium tocotrienols (shown in a double-blind randomized controlled trial to decrease bone resorption/breakdown and increase bone formation) and 300mg of geranylgeraniol.
You can find Annatrol Bone Support here:
👉👉 healthybonesco.com/products/annatrol
(1) Source: Nagaoka Y, Kajiya H, Ozeki S, Ikebe T, Okabe K. Mevalonates restore zoledronic acid-induced osteoclastogenesis inhibition. J Dent Res. 2015 Apr;94(4):594-601.
(2) Source: Chen, X., et al., Geranylgeraniol Restores Zoledronic Acid-Induced Efferocytosis Inhibition in Bisphosphonate-Related Osteonecrosis of the Jaw. Front Cell Dev Biol, 2021. 9: p. 770899.
(3) Source: Zafar S, et al “Effects of zoledronic acid and geranylgeraniol on angiogenic gene expression in primary human osteoclasts.” J. Oral Science 62 (1):79-83, 2020.
(4) Source: Koneski F, Popovic-Monevska D, Gjorgoski I, Krajoska J, Popovska M, Muratovska I, Velickovski B, Petrushevska G, Popovski V. In vivo effects of geranylgeraniol on the development of bisphosphonate-related osteonecrosis of the jaws. J Craniomaxillofac Surg. 2018 Feb;46(2):230-236.
**These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.
So it sounded like these are two separate products. Does he recommend to take both for bone health??
And would this be two separate pills?
These are two separate nutrients each with their own specific health benefits. Both of these nutrients can be found in one single pill called Annatrol™ Bone Support by Healthy Bones Co.
Two tiny pea sized capsules a day deliver the nutrients and potential health and bone benefits.
You can find it here:
👉 healthybonesco.com/products/annatrol
Does the product work if I already have osteoporosis & osteopenia, pls & thank you, this product sounds like what I need
I would say it’s even more important if someone has osteopenia and osteoporosis.
Tocotrienols have been studied in a human clinical trial of postmenopausal osteopenia subjects and reductions in bone loss were observed. In this 12-week study of 87 postmenopausal women, DeltaGold® annatto tocotrienol was administered at dosages of 300 and 600mg/day. Both doses led to decreased bone resorption and improved bone formation. One bone biomarker, the BALP/NTX ratio, which is a measure of bone remodeling, increased 100% after 12 weeks. In addition, the RANKL/OPG ratio that indicates bone resorption is high was reduced 13-24% after 12 weeks, whereas this ratio increased 21-36% in the placebo group. Furthermore, the use of annatto tocotrienol for application in postmenopausal women was shown to be safe.
Healthy Bones Co. Annatrol™ Bone Support also contains 300mg of Geranylgeraniol (GG), a compound synthesized endogenously in the human body via the mevalonate pathway-the same biochemical pathway by which cholesterol, vitamin K2, steroid hormones and ubiquinone (CoQ10) are synthesized. As such, it plays a critical role in tissue systems and metabolic processes throughout the body, including healthy mitochondrial function and the generation of ATP-the currency of energy in all mammals including humans.
GG occurs naturally in various foods, but the majority is synthesized endogenously. GG is an essential building block that supports protein synthesis, muscle health, bone health, hormone regulation and CoQ10 synthesis. Production of GG declines naturally during aging and is inhibited by use of certain pharmaceutical drugs, namely, statins and bisphosphonates.
Vitamin K2, also known as menaquinone, comes in different forms like MK-4 and MK-7, each with a unique structure. MK-4 is the primary form found in the body and is crucial for managing calcium transport, especially to the bones. Many studies have now confirmed, Geranylgeraniol (GG) is required for the synthesis of MK-4 in the body.
By replenishing natural levels, GG can protect from age-related physical decline, maintain structural support for the body and revoke skeletal muscle fatigue. Extracted from the annatto plant, GG-Gold® found in Annatrol™ Bone Support can help replenish GG levels.
Both of these nutrients can be found in one single pill called Annatrol™ Bone Support by Healthy Bones Co.
Two tiny pea sized capsules a day deliver the nutrients and potential health and bone benefits.
You can find it here:
👉 healthybonesco.com/products/annatrol
@@BoneCoach thank you so much for responding, I am ordering as soon as my SS hits my bank, can’t wait to order
We cannot get GG in UK at all.
I have spotted tocotrienols in UK. It is a bit pricey, but will order it, as I can now understand the benefits for recovery from osteoporosis and osteopaenia.
When will GG supplementi be available? This sounds awesome 🙏🏻
Lately I started wondering if I was getting enough vitamin E I know it's good for skin but I didn't know it was good for bones and MK4 is better for bones and MK7 ? I take a vitamin K supplement that says it contains all forms of vitamin K up to K 10
But is it better to just take a concentrated MK4 version?
Oh I felt like crying when the doctor started talking about the dentist and necrosis of the jaw , I have badly crooked teeth and recently got told I have gum disease even though I take very good care of my teeth for years but having crooked teeth is a risk factor,, my teeth hurt they're so uncomfortable I can't afford braces but even if I could the orthodontist told me I could lose my teeth due to my osteoporosis 😞 I know if I was taking osteoporosis medication no doubt it would destroy my jaw
I've already lost some jawbone I hope GG supplement becomes available soon 🙏🏻🙏🏻
Great to hear from you 🙂
Search for Healthy Bones Co. Annatrol on Google.
You can also find the product we discussed here.
=> healthybonesco.com/products/annatrol
Fortunately this is already available! You can find it here or by Googling “Healthy Bones Co. Annatrol”
👉 healthybonesco.com/products/annatrol
@@BoneCoach oh Awesome thank you I'll check out this link 🙏🏻 thank you ❤️
Your body makes GG.
@@vibhaspalding6457 it does?
Are there foods that can increase the production?
Is there a way to get a coupon code for purchases, or is there only a discount with a subscription?
Great question! Subscriptions always save 10% and you can always pause that later.
You can also sign up for the Free Strong Bones Kickstart at the bottom of the page and you can get a one-time use code for 10% off without subscription.
Scroll to the bottom of this page and you can see it 🙂
👉 healthybonesco.com/products/annatrol
Buy actual annatto and put it in a cheap coffew grinder. I eat mine over poached eggs...
Is there an agent in Australia for the products please??????
Hi, Tocotrienol is available at Design for Health australia
What if you have ITP?
We’re going to look into this 🙂