Stereochemistry - R S Configuration & Fischer Projections

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  • Опубліковано 26 лис 2024

КОМЕНТАРІ • 495

  • @TheOrganicChemistryTutor
    @TheOrganicChemistryTutor  3 роки тому +68

    Organic Chemistry PDF Worksheets: www.video-tutor.net/orgo-chem.html
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    PDF Worksheet - 38 Sub-Problems: bit.ly/3HaeWas

    • @realndu
      @realndu 3 роки тому +6

      Thanks Man! Hope to get a like :)

    • @Curiousviewer23
      @Curiousviewer23 Рік тому +6

      In minute 17:00 shouldn't there be 9 chiral centers and not just 8. I am referring to the carbon under the second carbon that you numbered. Isn't that also a chiral center since it is attached to 4 different groups?

    • @macysnatural8144
      @macysnatural8144 Рік тому +2

      @@Curiousviewer23 I thought the same too but I just goggled for the structure of cholesterol and he has the wrong structure....the particular c you speak of own the double bond too that was put away

    • @sammuelboateng282
      @sammuelboateng282 Рік тому

      Thanks man, i don’t usually go to class I learned from you 🙌🙌🙌🙌

    • @ThariCute
      @ThariCute Рік тому

      ​@@Curiousviewer23 samee!!! Doubt

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    @bluefdg10 3 роки тому +2186

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  • @user45601
    @user45601 2 роки тому +384

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    • @amdkits
      @amdkits 2 роки тому +5

      Bro what happened if you take norflox by mistake? I accidentally took one

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      @p-dawgisaregisteredsexoffe7890 Рік тому

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    • @amdkits
      @amdkits Рік тому

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    • @hexcoff1689
      @hexcoff1689 Рік тому

      Same here

  • @saraparrish3756
    @saraparrish3756 Рік тому +198

    TY, I appreciate all your hard work. I watch many of your videos and they have helped a lot! ***Possible CORRECTION? looks like the cholesterol molecule in your video has the double bond in the wrong place. *** I kept going over and over this and could not understand why Carbon-5 (the one due south of the methyl group) was not a chiral center? As the figure is drawn, it should be...which would make 9 stereocenters, not 8. But when I looked up cholesterol, the double bond is actually between C-5 and C-6 not as you've shown it. Just in case anyone else got stuck on this problem.

    • @yevheniiavelihina1197
      @yevheniiavelihina1197 Рік тому +4

      Same for me

    • @DrTuph
      @DrTuph Рік тому +22

      Thanks for this comment. I've been sitting here the past few minutes trying to figure out why there would only be 8 given the drawing in the video. After looking up what cholesterol should look like, it makes sense.

    • @boatman3132
      @boatman3132 Рік тому +2

      I have struggled for this question as well until I found out your comment.
      It seems that there are 2^9=512 different stereoisomers in cholesterol.

    • @dukeaboagye3099
      @dukeaboagye3099 Рік тому

      thanks can't believe I realized it

    • @pfelixtutor8738
      @pfelixtutor8738 11 місяців тому +1

      I saw that too, the double bond is in a wrong position. All the same thank you 🙏

  • @michaelc2946
    @michaelc2946 Рік тому +37

    the double bond in the cholesterol is incorrect. it needs to be moved one bond to the left. I kept thinking there were 9 chiral centers until I googled it. Keep up the great work!!

    • @wdzcix
      @wdzcix Рік тому +9

      i was so confused on that lol

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    @junovalentines3304 Рік тому +37

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    @maueenmothapo6011 3 роки тому +134

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  • @paulnegoita5769
    @paulnegoita5769 3 роки тому +360

    17:08, isn't there another chiral center below carbon #2, since first bond goes to a sp3 C, second to sp3 CH2, and third to a sp2 CH and a hydrogen?

    • @FBWUniverseMode
      @FBWUniverseMode 3 роки тому +56

      yess there are 9 not 8 chiral Cs

    • @oluwajobipeterpelumi1279
      @oluwajobipeterpelumi1279 3 роки тому +41

      Brilliant you are correct.. Wanted to ask too

    • @xeel224109
      @xeel224109 3 роки тому +90

      Yes, he drew the molecule with the double bond in the wrong place. Cholesterol has 2^8 isomers but the drawn molecule has 2^9.

    • @n_7458
      @n_7458 3 роки тому +29

      He made a small error and drew the double bond in the wrong place. So, you're right that the molecule shown has 9 stereocenters! In reality, cholesterol only has 8. You can confirm this by googling the molecule. xx

    • @Scifiotica
      @Scifiotica 3 роки тому +8

      @@xeel224109 Oh thanks I thought I had lost it there! Now it makes sense.

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  • @PunmasterSTP
    @PunmasterSTP 3 роки тому +58

    Another incredible video; thanks so much for posting! If the hydrogen (or lowest priority group) isn't where I want it to be, sometimes I just exchange two groups to make that happen, and remember that that inverts the stereochemistry (R -> S or vice versa).

  • @tanviaher1150
    @tanviaher1150 10 місяців тому +8

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    • @TheOrganicChemistryTutor
      @TheOrganicChemistryTutor  10 місяців тому +6

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      @allwasmie 9 місяців тому

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    @kowatheeexplorer9093 2 роки тому +10

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  • @nightmarefredbear7739
    @nightmarefredbear7739 3 роки тому +524

    Ah,lets learn stereochemistry at 1 AM

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  • @Billybingo69
    @Billybingo69 15 днів тому +3

    At first I thought that you missed a chiral center (the tertiary carbon directly underneath chiral #2) but I looked it up and the double bond you drew was just in the wrong place! That carbon is supposed to be sp2 hybridized, just FYI for anybody else confused.

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  • @ZoeZhiXiu
    @ZoeZhiXiu Рік тому +4

    The position of the C=C in cholesterol is wrong, according to your drawn diagram, there should be 9 chiral centers, but for cholesterol, there is only 8 because of the positioning of the C=C. But other than that, I loved the video and it helped me a lot in understanding stereochemistry.

    • @Airraca
      @Airraca 9 годин тому

      actually i thought so too but there's actually only 8.. even with the double bond placement

  • @jannatstyle45
    @jannatstyle45 Рік тому +9

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    @abdullahasif9812 2 роки тому +4

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    • @maryamshafeeq1423
      @maryamshafeeq1423 7 місяців тому +1

      This is actually difficult, I couldn't understand 😢

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  • @nathanmanning3816
    @nathanmanning3816 Рік тому +11

    For Q3, the one assigning chiral centers for Cholesterol, would there not be a chiral carbon just below the 2nd chiral carbon? It is attached to a sp2 hybridized carbon, the carbon with a methyl group, and a ch2 carbon that eventually leads to an alcohol

    • @ayaansurti2876
      @ayaansurti2876 Рік тому +9

      yes, it is chiral so there are 9 chiral centers

    • @felipe-n9t
      @felipe-n9t 11 місяців тому +2

      Yes, he drew the double bond incorrectly, the two cicle hexanes are supposed to be "fused" via a double bond between the carbon under chiral carbon 2 and the carbon to it's right, so in the cholesterol molecule there are only 8 chiral centers, but the molecule shown in the video has 9 chiral centers.

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    @vakalevuvinaka8570 3 роки тому +6

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  • @TUTORFREDOXIDE
    @TUTORFREDOXIDE 23 дні тому +1

    Keep up with the great work .... the double bond should be between carbon 5 and 6

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  • @SidneyFlo
    @SidneyFlo Рік тому +16

    When identifying the chiral centers on cholesterol, I think you accidently missed one and it would be 9 instead of 8. Isn't there a chiral center on the carbon below the one you indentified as 2?

    • @XQJimmy
      @XQJimmy 10 місяців тому +2

      You are right! Based off of his structure, there are 9 chiral centers. However, the double bond in his cholesterol drawing is in the incorrect position; it should be moved one spot to the left. After that change, there will only be 8 chiral centers

    • @Me-bk3bj
      @Me-bk3bj 2 місяці тому

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  • @kshitijgoyani4389
    @kshitijgoyani4389 3 роки тому +8

    at 17:30 there is an another chiral carbon on the left of the double bond

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  • @Sam-qf7hk
    @Sam-qf7hk 2 роки тому +1

    Mistake: Hey Erm, i think u made a mistake in the position of the double bond in cholesterol. Thanks, and great video!

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  • @strabo1828
    @strabo1828 3 роки тому +32

    17:07 Shouldn't the tertiary carbon beneath the one numbered 2 be counted as a chiral center?

    • @alanc6468
      @alanc6468 3 роки тому +15

      He drew cholesterol wrong, there should be a double bond there.

    • @aaliyahnuma4176
      @aaliyahnuma4176 3 роки тому +8

      thank you for asking this because i was confused why it wasnt considered as one

    • @mahdialachyarendriko8893
      @mahdialachyarendriko8893 3 роки тому +6

      he misplaced the double bond,

    • @princeslime831
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    @noturecologist Рік тому

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  • @carolinnicolai615
    @carolinnicolai615 3 роки тому +17

    I've got a question regarding the Hydrogen Atoms in the Cholesterol Molecule. Did you follow any rules when placing the Hydrogens in between the Carbon structure regarding their position behind or in front of the planes? Or is their position arbitrary? Thank you so much for this great tutorial. It really helps!

    • @seungminned0922
      @seungminned0922 2 роки тому +1

      Can anyone answer this? I wanna know too. Thank you to the one who will answer.

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    @razasyed575 Рік тому +1

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  • @minkim4374
    @minkim4374 Рік тому +1

    When you explain chiral centers in cholesterol, there is an error in cholesterol at 17:17. The double bond should be on Carbon 5 and 6 not on 6 and 7.

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    @acadvids8668 3 роки тому +1

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  • @jeewakasilva7879
    @jeewakasilva7879 Рік тому +1

    Dear Sir, The double bond should change the position in the cholesterol molecule.

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    @blockhead4221 3 роки тому

    It litteraly 1 minute you the best

  • @WolMaror-wi5ly
    @WolMaror-wi5ly Рік тому

    So helpful in understanding Stereochemistry ❤

  • @TheGuy9000000
    @TheGuy9000000 2 роки тому +5

    In problem 3, why is the tertiary carbon closest to the double bond not considered a chiral center? I am talking about the bottom right carbon on the farthest benzene to the left of the cholesterol.

    • @quinnparker3863
      @quinnparker3863 2 роки тому

      I noticed that too, I think he just over looked that one

  • @geoffacabado
    @geoffacabado Місяць тому +1

    On the cholesterol example, why isn't the tertiary carbon directly below the 2nd chiral carbon considered as a chiral center?

  • @Julie-fh5gi
    @Julie-fh5gi Рік тому

    thank you for simplifying ochem!

  • @noahmartin2130
    @noahmartin2130 2 роки тому +7

    For number 3, why is the carbon below the second chiral center NOT a chiral center?