How to Draw Fischer Projections
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- Опубліковано 10 лют 2025
- Leah4sci.com/F... presents: Introduction to Fischer projections including how to quickly draw and interpret them for molecules with single and multiple chiral centers
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In this video you’ll learn all about Fischer projections including what they are, how to read them, how to quickly draw and convert 3D molecules into Fischer projection and back without ever having to build a model kit.
You’ll learn a number of different methods for converting 3D to Fischer from small molecules containing a single chiral center, to complex molecules like D-Glucose containing multiple chiral centers.
You’ll also learn what happens when you rotate a Fischer Projection 90 and 180 degrees.
↪ Additional Links & Resources ↩
▸Fischer Projections Series + Cheat Sheet Leah4sci.com/F...
▸Chirality and Stereochemistry Series + Cheat Sheet Leah4sci.com/C...
▸How to Use Your Organic Chemistry Model Kit Leah4sci.com/M...
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⏱ In this video:
[0:18] Interpreting Fischer Projections - Mr. Organic Chemistry
[0:56] Drawing Fischer Projections from 3D Structures
[3:09] Rotating Fischer Projections
[4:06] More than One Chiral Center - Example #1
[7:01] More than One Chiral Center - Example #2
[7:58] Turning Fischer Projections into 3D Structures
[9:01] Multiple Chiral Centers - Glucose Example
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Thank you mam, you literally had no idea how I was stuck with this concept for a month! The concept of rotation was beautifully explained too. Thank You.
You're so very welcome! I'm thrilled I was able to clear things up for you
Soooo helpful. Never seen it explained like this before. Seriously saved my life
Nice! So glad this filled in the holes and helped you understand!
thank you sooo mucchhhh, this is the only video i understand after hours and hours trying to understand it 😭😭
I am SO happy to help you understand it quickly and easily!
That was genuinely helpful, thank you sm. The only video/article that explained it well and in an easy manner!
So glad it was helpful!
You are the only person I have been able to understand when explaining this concept, thank you so much lol. My ochem final is tomorrow hehe
I'm glad I helped clear it up for you, how did your final turn out?
You're a savior. Thank you so much. ❤
Aww, thanks and you're so welcome!
Tank you mam .the way you taught was really easy to understand
You're very welcome! I'm glad you found it helpful
This video is genius! This is the way I wish I was taught things 💕
Wow, thanks! I'm so glad you not only liked the information but how it was presented!
Great video. The left/right eye method is one in which I will never understand. I'm sticking with the R/S guess/check method
Sounds like you found what works for you! Thanks for watching!
WOOOWWWWW Thank you soooo much for this break down!
Question: How do you know which side to place the invisible H? Left or right of the atom in front?
You are very welcome! As for where to put the invisible H, if the molecule is drawn with stereochemistry you can
1- look at the visible sub (dash/wedge) and place accordingly, then put the H on the other side
2- you can draw in the appropriate dash/wedge/line for the H and then place accordingly
how do you know where to place the head? is it based off priority? because for example at 4:24 you placed the head on top where you can see bromine coming towards you to your left eye but at 7:23 you placed the head at the bottom. You said you can place the head anywhere but it changes the way you view the molocule. So question, how do you know where to place the head?
Since molecules can rotate in space, it doesn't matter so long as you can follow what you're doing. I typically choose to place my head where there are bigger or bulkier substituents facing me as that is easiest for me to visualize. if the bigger/bulk is facing away then I have to do mental rotations or switching which adds extra work
@@Leah4sciMCAT I love that you reply to comments. Thank You
thank you!
you're very welcome!
THANK YOU!!
You're welcome!!
why do i have a crush on mr organic chemistry
I'm not sure?
I really like the ways you simplify everything and have awsome mnemothech! Can you do a video about glycogenesis.. really I can’t understand..
I hope to tackle all of the different biochemistry pathways at some point soon
I hope you anderstand my question,
if the Newman projection is staggered but in different way than you wrote, for example the H atom is up in the front carbon, what should we do? to turn it to fisher?
I hope you answer me quickly cause I have an exam and I didn't got it 😢
I'm sorry for the late response! However, this video does not have any Newman projections in it. I'm struggling to understand your question, based on this video.
If you would like to ask further questions, please provide the video and time stamp and contact me through my website at Leah4sci.com/contact
@Leah4sciMCAT
Thank you
I got A- in organic chemistry which is 96%
❤️❤️❤️
need more content on basics for orgo 1
I have an entire youtube channel for that leah4sci.com/youtube
I understood the left eye right eye method.but in 1:48 ,how we know the exact direction we should keep our eye? I drew the fischer projection from keeping eyes from up like 5:37 So the structure got different than what you got.in this sturcture, u kept the eye from downwards.how we know the exact position that should keep the eye.Is there any trick?
Given that molecules can rotate in space, so long as you remain consistent it doesn't matter where you place your eyes. Meaning, if you looking at it from one angle and draw it correctly, even if I look at it from another angle and the molecule is drawn from a different perspective, as long as we both did it correctly it should be ok. Compare your structure to mine, is the stereochemistry the same? If yes you're good even if it looks a bit different
Mam the Fischer projection is changed according the way and the side we see.is it ok?
Thankyou madam I think I am about to understand
Happy to help!
tysm for making the video! i just want to ask why do we have to look in that way to figure out fischer projections? tysm for your help ^ww^
You're very welcome! As for why do we have to look at it this way, I'm not sure I understand what you're asking
Please how do you know if you should look at the molecule from left side or right side or whether to look from the top or down?
Since molecules rotate in space, it doesn't matter if you look at it from the right or left. Just make sure the perspective lines up with whatever form you're turning it into
sorry,but may i know if the guess and check method,for the up down group,is it ok to put it reversely if I just check the R and S starting from the group corresponding to the 3D structure,for example,I put the CH2OH on the top in the last example, and use the guess and check method and get the fischer projection,is it equivalent to the example one? thank you
As long as configuration remains the same, it's fine to rotate the Fischer projection by 180 degrees. However, convention usually dictates us putting the aldehyde at the top.
If wanting a faster way to identify configurations in a Fischer projection, make sure to my Fischer projection stereochemistry trick here: ua-cam.com/video/lf6hLBl6wxo/v-deo.htmlsi=TZEb0343pEX7AVMk
Hello ma’am a regular viewer here.
Can you please tell me position of dash H like how you decide where to put it. Im really really confused please help me
In this video, we were drawing Fischer projections when given the 3D sawhorse drawing. In other words, the dash H was given to us in the question and not something we were asked to draw. If you have a more specific question, feel free to reach out to me through my website at Leah4sci.com/contact and provide the video and time stamp that you're needing help with.
It's not easy only she understands 😅
I'm sorry you're having trouble, what can I do to clear things up?
You should do one where you have to get the methyls on the same plane before converting into a fisher no videos explain this.
Why would you want to get them in the same plane? Why not just convert from whatever form you're given?
man what the fuckkkk, this is killin me
This is a tricky topic, hopefully it feels a bit better by now
I don't want to know where Mr. Organic Chemistry wears his second bow tie. I knew he was a perv. 😂
😆🤦 on his neck? on the first button of his shirt?
well shit
Good or bad?
I don't get it, 7:49 i did the guess and check method and in the left they were both s configuration but in the fisher they are both R
Remember that, in the Fischer projection, the Hydrogen is coming forward out of the paper. In order to find the correct configuration, we must move that hydrogen to the back of the molecule.
The swap method can be really helpful for finding configurations in a Fischer projection. See this video for my Fischer Projection stereochemistry trick: ua-cam.com/video/lf6hLBl6wxo/v-deo.htmlsi=TZEb0343pEX7AVMk