Methylcobalamin vs Cyanocobalamin: Which version of B12 is best?
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- Опубліковано 24 сер 2024
- Methylcobalamin vs cyanocobalamin: which one should you take? Both of these are versions of vitamin B12 but differ dramatically in how they are processed by your body and/or utilized. Even though they both contain vitamin B12 they are NOT created equal with one being significantly better than the other.
But first, why would you even worry about using a B12 supplement? Because B12 deficiency is so common! It is one of the most common nutrient deficiencies out there and it leads to symptoms such as weight gain, depression, and fatigue.
Because it's so common, B12 is often added to various supplements to help improve those symptoms. Unfortunately, many manufacturers of B12 supplements use the wrong form of B12 which can cause issues.
Methylcobalamin vs cyanocobalamin: What's the difference?
While both of these contain vitamin B12 the difference between these two is in what the B12 is bound to. In the case of cyanocobalamin, the B12 is bound to Cyanide.
This cyanide must be eliminated and detoxed out of the body.
Even though it doesn't cause damage to your body it's still something that should be considered. Lastly, cyanocobalamin is not naturally found in nature unlike methylcobalamin which means it's synthetic and manmade.
Methylcobalamin, on the other hand, is basically the exact opposite. Methylcobalamin is the form of B12 found in food and occurs naturally. In addition, it doesn't require detoxification of cyanide and comes in its pre-activated and pre-methylated form which means that it is easier for the body to use.
For these reasons, it's ideal to use methylcobalamin.
Is cyanocobalamin harmful because it contains cyanide. Studies have shown that it doesn't cause harm and the amount of Cyanide contained is so small as to not cause toxicity. Having said that, it doesn't sit well with me using a product that contains a potentially deadly product so I prefer to avoid it.
You also should be aware that there are several ways to put B12 into your body. These include: B12 injections, sublingual B12, and oral B12 capsules/tablets.
You may need to play around with what works best for you, but I have found that B12 shots tend to be the best as they bypass absorption in the gut and get straight into your cells.
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Disclaimer:
Dr. Westin Childs received his Doctor of Osteopathic Medicine from Rocky Vista University College of Osteopathic medicine in 2013. His use of “doctor” or “Dr.” in relation to himself solely refers to that degree. Dr. Childs is no longer practicing medicine and does not hold an active medical license so he can focus on helping people through videos, blog posts, research, and supplement formulation. To read more about why he is no longer licensed please see this page: www.restartmed...
This video is for general informational, educational, and entertainment purposes only. It should not be used to self-diagnose and it is not a substitute for a medical exam, treatment, diagnosis, prescription, or recommendation. It does not create a doctor-patient relationship between Dr. Childs and you. You should not make any changes to your medications or health regimens without first consulting a physician. If you have any questions please consult with your current primary care provider. Restart Medical LLC and Dr. Westin Childs are not liable or responsible for any advice, course of treatment, diagnosis, or any other information, services, or product you obtain through this website or video.
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"But it has cyanide in it!!"
ok? loads of foods have cyanide in them. Have you ever eaten almonds? It's not enough to be harmful to you. And remember that ur body converts cyano to methyl.
And just because cyano is man-made does not mean it is bad for you. Lots of medicine is man-made, yet beneficial for you.
Love love love you Dr.! And thank you Jesus for this Man/ child of God
Thank you. So well explained.
No 2 people are alike. But with that being said would you ever share your regime? Such as what you take but detailed info such as 1 shot of B12 per week of x amount. What benefits you notice immediately. Side effects of anything you have used etc. I feel you already make such EASY to digest understandable educational vids and this may take them even to the next level. Also please do vids on Liothyronine, how to read labs when on it or what to look for, when to take of getting labs done, what to do when t4 and TSH plummet.
I started out one shot a month and it only took few months to get it up. Then just on sublingle 1000 a day
Great info here , glad I listened to this and get rid of B12 Cyanocobalamin and take my B Complex that includes B12 that I bought from you 😊
This was very informative, thanks Doc!😀
Thanks for the KNOWLEDGE!!!
Yes, I am taking B12 in the methylcobalamin form, sublingually.
Can anybody help me?
i'm taking mecobalamin sublingual and you can get 6000mg doses, maybe that could make up for what isn't absorbed if you swallow it ?
Dr. Westine Childs, as we know Cyanocobalamin is metabolized into two active forms:
adenosylcobalamin in the mitochondria and methylcobalamin in the cytosol. If one has B12 deficiency, then taking only the active form of B12 supplement (Methylcobalamine), would leave the body without adenosylcobalamin which is needed for energy production? Can you explain please? Thank you!
I didn't know that about Methylcobalamin, and I will investigate. Did you ever get an answer to your question
I have pernicious anemia....B12 cyanocobalamin injections are 1x per month for the last 5.. i feel like i am on a rollercoaster...2 weeks after injection symptoms return..... maybe methylcobalamin injections would keep me feeling better for the entire month... thanks
I did some internet research when I started B-12 and not knowing the difference bought the Cyano version. I decided to get the Methyl a week later and have trusted it to help ever since...about 5 years now. I take 2000 per day. What is a correct dosage for a 295 lb human version of the Goodyear Blimp? Great video, I have a friend whose wife just started taking Cyano injections. He stubbornly refuses to talk to his doctor about switching, So, in the mere chance that he may look nto my Facebook posts, I planted the link to this video on my page. Thanks a lot for clarifying via a well explained video. Oh, my friend's wife has an extremely bad heart condition so I worried about the 1000 mcg doses he must give her, soon to be monthly.
Thank you, Doctor, that was clearer than water . Is What I needed to know. I'm subscribed now.
Great Video!!
Someone said that the liver usually removes the cyanide, but if the liver was not working to full level or if it was already inundate with toxins that it may have trouble.
I appreciate you explaining the cyano. I worked in the semiconductor manufacturing field . One of the my projects was to plate electroless gold on on certain components the electroless gold solution was suspended in a cyninde solution. I've wondered if that contributed to not having a positive reaction when receiving cyano injections where the methyl injections I would get a positive reaction most always within 10 minutes. I have PA and my father also had PA.
@@ralphc8039
More likely you have genetics which don't handle cyanocobalamin well. It's not something our bodys has evolved to deal with.
The amount of cyano isn't likely to be enough to do any harm. But it's unneccesary, of course.
But methylcobalamin, adenosylcobalamin , and the hydroxycobalamin forms are what our bodies know to handle, so stay with those.
The research tells us that any of the three natural forms will work. They all do the job about the same, except for details in absorbtion, which we can only guess about.
Thanks for the valuable info .I m in the market for purchasing a b12 supplement before I purchase I thought I would research the variance in supplements.
I do take b12 and now heading to check the bottle. Ay yay yay!
I have felt that Cyanocobalamin is better than methylcobalamin to treat anxiety.
I gave up on Methylcobalamin (1000mg) after three days bc i was about to jump out of my skin with anxiety and strange psychological reactions. Taking the same amount (1000mg) of Cyanocobalamin after discarding Methyl , there are no strange reaction and all is normal. You might want to adress this Dr. Westin. Reddit has a thread with dozens if not hundreds of people reporting the same kind of intolerance to methylcobalamin. Some of them severe and lasting and all of them put out a warning
I assume you know who Dr. Greger is. Here's his take on B-12: "For adults under age 65, the easiest way to get B12 is to take at least one 2,000 mcg supplement each week or a daily dose of 50 mcg. Note that these doses are specific to cyanocobalamin, the preferred supplemental form of vitamin B12, as there is insufficient evidence to support the efficacy of the other forms, like methylcobalamin."
Very very informative so grateful. I've had 2 injections in India that helped my defficency
Everywhere that I research, it states that cyancobalamin is the better choice.
Paid by and for your big pharma. Cheaper is better for their wallet, who cares about ur health.
Ok I found it. I read the best B12 to take is Adenosylocbalamin
Global healing has liquid b12 with methyl hydroxy and adeno
Hi i found your comments very usefull.i am using injectadle B12 cyanocobalamin, every two weeks. Now sinse i watch your comments i try to find methycobalamin and it is imposible throu farmacies and health stores.I live in canada province of ontario north area small town.iam 76 years old and i suffer from severe periferal nevropathy.Please Advise. Thank you in advance. George C.
This is not accurate. Our body need both methylcobalamin and adenosylcobalamin. So if you only take methylcobalamin you can risk being deficient in Adenosylcobalamin. Whereas the synthetic cyanocobalamin will convert into these two forms more effectively.
But Cyanocobalamin is made from human waste sludge, what do you think about that?
You are right. Cyano form can be converted into both forms.
Cyano doesn’t work for me. Meryl I feel it working. I don’t process it. So methyl sublingually works best.
I’ll be switching to methyl
My pharmacy didn't even carry the methyl form..
I can't remember what the name was but I watched a video and she said the B12 to use started with A but can't remember what it was. Does anyone know?
Adenosylcobalamin
Adenosylcobalamin is the best. Hydroxocobalamin injections are also very good.
The methylcobalami is hard to get because it is better
Great video
What about Natural yeast it's more natural and has all vitamin B12.. 👍🏻
Now one cannot find any yeast with natural B vits. If B12 is in the nutritional yeast it's fortified. If the ingredients list different Bs that means they were added. I can't find any nutritional yeast that's NOT fortified.
@@peace1108 I have unfortified nutritional yeast that us filled with B12.
@@acdcmiami you have unfortified yeast with B12?
Is methylcobalamin unstable?
At pH 3, methylcobalamin was the most unstable showing 79% degradation loss, which was down to 12% after sorbitol was added (p < 0.05). The losses of cyanocobalamin at pH 3 and pH 9 (~15%) were prevented by adding sorbitol. Addition of sorbitol to hydroxocobalamin at pH 3 and pH 9 reduced the loss by only 6%.
What is the dose of cyanocobalamin and methycoblamin
Awesome stuff
If Cyanocobalamin has issue as its attached to Cyanid then giving that same argument H2O i.e. water is also bad. Both Hyroden and Oxygen help to burn.
Good video. Dr Childs talks fast and clearly, he packs a lot of good info into his videos. Thanks.
I take one 1200 mcg tablet per day. Methylcobalamin. Swallow. Costco canada, it's inexpensive .
I'm vegan, I have no b12 problems, but I'm aware of the vegan/B12 issue.
Thanks, I watched another YT and they recommended if you take supplements to put them under your tongue. Is that an option with the Costco brand?
After taking Armour for only 3 days I developed some tingling all over the body. It’s been 12 days now since I stopped it and the tingling is still there, didn’t expect this side effect, wondering how long it will last. I am very sensitive to meds. Thanks I love your content. 🙏🏻
As I recall, Armour is made with GLUTEN
Yes Tingling D3 had help me and l dont feel anymore tingling. And also Glucosamine good for me .
Actually animals are supplemented with b12, which I believe is also cyano
I can assure the wild fish I eat are not injected with b12! Nor is the organic beef I buy. In fact it's uncommon to give any cattle b12 supplements unless they are unwell. Cows get it from their gut bacteria and always have done.
YEP!!
@@Jack-ye6fm That is incredibly naive. Farmers are giving all their animals b12 regularly, they are not checking to see if a few in hundreds are a bit sick. They are also giving them 5-in-1 whatever you call it to keep them healthy.
@@Jack-ye6fm bro animals gut dont have b12 already .. they have to be given in some form... Your body cant produce b12 on its own.. the foods that beef and fish eat they do is mix supplements in them
@@nickmeale1957 Factory farmers might be doing it along with the antibiotics and hormones and everything else, but pasture raised cattle from family farms and local farms are not injected with B12. I grew up on a cattle ranch and we never used B12 injections.
Hey doctor! Do u have a guide to finding a good doctor? I feel so lost and helpless. The brain fog my hypothyroidism is causing is ruining my life, and I just can't motivate myself to do anything.
🙏🏻
Same. I can’t concentrate.
@@ayieisondeleon4534 🙏
What brand give you the right one Thank you
Question: I have been told i have a NAFL and given some B12 and changed my diet completely which B12 is best in my situation.
I switched to only bang energy now because that’s the only one I can find without poop in it
Thank you Dr Westin.....Most interesting....A Question for forty years, on originally discovery a B12 deficiency which led to a poor B12 absorption, I have been receiving Methylcobalamin injections which started as twice a year increasing to two every two months, this is the only way of stopping pins and needles in my legs. Doctor yesterday suggested a high dose, 1000micro grams, orally. I see Solgar offer two different types, which you cover in your video.....Doctor told me that there is recent evidence that a high dosage orally can be as affective as injections..../do you have any comment on this?
I place my bet on methyl...
shots can be also very cheap if you do and buy everything yourself, like the b12 injection doses from hevert and all other things. you get to 1€ per shot.
i did this many times myself
How do we go about getting the shots the b twelve shots
sorry to say but methocobalomin didnt cure my b12 difficiency. rather cyanocobalamin worked best for me.
also I see a lot of experienced health professional like dr neal barnard, dr Michale greger, dr michale klaper and ............ suggest cyanocobalamin form over methcobalomin.
How much b12 was in your Methylcobalamin supplement? Was it a hard pill or liquid? Was it a daily or weekly supplement? I just found out my supplement is also Methylcobalamine 😟
My body not absorb methylcobalmin
So best absorb cyanocobalamin
Hi. Did you take cyanocobalamin injections or capsules?. I think the same cyanocobalamin can reach deeper in body but slowly. And methylCbl is only 1 form of b12.
@@OneEarthOneFamily1947 both capsule and injections works the best.
Mine was capsule.
@@sayuktaojha5015 What problems did you have before starting the supplements. I have many problems like anxiety panic and nerve tingling numbness. I tried methylcobalamin. It lift my mood but nothing for panic and nerves.
Wow! I just took a look, and the B12 I have is cyanocobalamin!
It's the cheapest version so it's commonly found in cheaper supplements. One of the many reasons to buy high quality supplements!
Same here and I have 4 bottles.
Hi I'm 53 y/o, 56kg newly diagnosed diabetes type 2 on Metformin 2g perday. After 1 month on Metformin I've started to have B12 deficiency symptoms suc as fatígue, mood swing, low concentration, dry tongue on night. I've just bought capsule Methylcobalamin 1500 mcg as for replacement. Is it indicated?
So....injectables...for a normal 200 pound man....20% body fat...what gauge needle is best for the IM....
second....where might one get a good source of injectable Vitamin B12 please. What is a good Loading dose and then ongoing therapeutic dose and how often please.....for a person exhibiting most B12 deficiency signs; twitching, some difficulty walking, forgetfulness, irritability, etc.
It’s crazy that they put cyanocobalamjn in body armor and prime, even thought it’s under 4 micrograms why not just use the methyl form
I do Sublingual b12, Methyicobalamin 5000mcg. I ml dropper daily
😂😂😂😂
What do you think Westin, of T3 supplinentation with Tirosint if wanting ti get pregnant, and during pregnancy?
Do you have hypothyroid? If so, it always in remission when you are pregnant. I was surprised that after giving birth I lost 40 lbs in 3 weeks without even trying.
Eat right while pregnant and take all the vitamins before and during pregnancy and add trace minerals and you will be amazed. You won't even have those crazy craving, nausea etc.good luck
@@DarkAngel-cj6sx Thanks ... its not regarding weight ... Im thinking of safety for the baby and me - I have hashimotos, and taking Tirosint, my THS is 0,04 and with very low T3 and I wish to try T3 or NDT to see if I feel better 🌺🌺🌺 and wish to become pregnant 🌺 and Im not sure if I can supplement with T3 when I wish for a pregnancy ...
In Denmark I have no trust in endokrinologists ...
So what brands of b12 supplements are best?
Global healing
I use Mary Ruth’s organic for my supplements.
Don't you need a prescription from a doctor to use the B12 injections yourself? I know how to do shots, needles, etc., but can you even buy injectable B12 without a script? How much do you need for a deficiency?
A Dr has to prescribe it. My Dr prescribed Vit B12 for me because he said never take those over the counter vitamins and supplements because they're made in China and other countries that do not inspect them and you never know what is in those.
How will I know which type of B12 the injection is ?
Sr i some liver issue,my bilururbin increased 1.39 and b12 is 218 .dr give me cycnocobalmin 2.2 mcg sr is this enough potency then methyl
can i get Methylcobalamin in injections?
Should i trow mine with cynacobalamin away?
i did
witch brand give the b12
As soon as i learned this i returned the one i bought that has the cyanide and got the mythel kind.
Yes. I looked at my bottle and mine is cyanide too! Spring valley brand from Walmart! 2500 mcg.
@straightbeef, @nigma195, @StevenOsburnHollywood, @Footy_Shorts
I recently threw away my poo poo gummies and got me some Metilcobalamina!!! Wasn't cheap, but I'm feces-free!!! Funny, because I went to a market where all they had was the poop gummies, and then I went to a health food store ....they only sold *ONE* type of B12 supplement, with *METILCOBALAMINA!!!* that's it!!!
500micro gram, 1000 or 1500 ? Which should I take if I have 275pg..
Are you are really doctor show mi you credencials
Hi doctor, do u know a good doctor in New jersey?
Would you mind to address B12 via IV infusion?
Methylcobalamin. ✅
b12 methylcobalamin i take 2 caps of 5.000mcg in morning and after dinner b4 bed . i got type 2 diabetes . i also have b1 benfotiamine take 2 .300 mg and biotin 5.000 mcg .
How many mg should 1 shot be?
Hi , my B12 test came out and it's 357 pg/ml and i have the symptoms associated with B12 defficiency, should i take methyl B12 ? if so should i take after or before meal ?
Yes, it would be a good starting point.
Does bioperine aid in absorption?
What about b12 folate?
Would you recommend subw or inter muscular injections?
Woman.....have you NOT listened to this video? The best method is injectables. Come on.
What about liposomal B12?
Without the enzyme it won't absorb. A sublingual methylated pill is better.
@@Shiv1971 Do sublingual methyl versions actually bypass the gut successfully?
Dosage please
The first 2 ug of a dose is actively absorbed. The rest of the dose by much less effective diffusion.
Therefore, a very high dose of 500 or even 1000 ug might be needed to get more than that.
About 7 ug absorbed would be good, perhaps optimal. The RDA of 2.4 ug is low.
I would suggest supplementing with, let's say 25 ug three times a day. Because the uptake of higher doses seems to be severely reduced.
But that's just my idea. Most just take a very high dose once a day.
Methylcobalamin would work well.My guess is that 500 ug once a day would be pretty good for most people.
But intestinal problems can kill absorbtion! In that case, see a doctor.
I'm not a doctor. I've just researched this for my own purpose, finding out what's optimal for me.
Cyanocobalamin is made from RAW SEWAGE Sludge
So Helpful wowie, I love to learn. I have 100 ug in my complex really surprised me to learn, it makes me Leary of this so called all natural supplement from Flora. I take 1000 of the B12 methylation My blood work shows I have way to much B12 I was having shots because it was so low now levels are up I love the mental stuff that comes from B-12. Open to learn any ideas???🦅
Nancy Adams Do you know what is the OPTIMAL level of b12?
Thanks.
I’m No Dr. My ND has me on 1000
@@nancyadams4358 Thank you.
@@luzysombra5291 I’m glad your healing😊🐝
Why do I keep hearing people say that something does (or doesn't) occur "naturally in nature"?
When you encounter something that does (or doesn't) "occur in nature," isn't that the same thing?
thank you for the best video about b12, i going tomorrow to take the injection for my self and my parent..methylcobalamin and b complex.
nice
YOU NEVER ANSWERED MY QUESTION ..😒
Yeah seems like he just want to view's and enjoyed it
What a crap Dr
Can one take selenium and zinc together??
this is a silly question...why wouldn't one be able to?
Wise people always ask questions, telling someone the question is silly is wickedness and horrible.
Cyanocobalamin has cynide in it
My B12 came back as being 286. My doctor wants me to take 500 mcg sublingual B12 a day. I have been googling the different forms to figure out which one to take. Another doctor says the cyanocobalamin is the best one to take so I am still unsure.
Cyanocobalamin is definitely not the best form to take. Pretty much anything except cyano is a good idea.
@@drwestinchilds I emailed my PCP after seeing the differing opinions. He told me to please take the cyanocobalamin so that is what I am going to take.
@@saranelson841 gee, why not try both. its not like a big deal
I used to take cyano. Switched to methyl. And now taking 2000mcg and I’ve been fine since the switch. I don’t have a thyroid.
@@CERnoriVELO please share the name of supplements
Przetlumacz na pol 0:56 ski
Hi. My b12 level is 175 pg/ml. How much should i take to get it to the normal level and for how long ? Thanks
Mine is 183, my doc prescribed a 500mcg sublingual tablet.
@@mohsin_sait
Thank you !
Billion dollar industry
Mine was 2900 back in June. I stopped taking 5000mcg methyl B12 3 months ago. Noticed small tongue fissure this morning. What to do???
Did he reply to you
You might be deficient in zinc, vit B ( get the complex) or iron.
@user-ls2fh6qr8q added zinc and tyrosine about a month ago. Have not been retested. Feel good tho.
@00:53
Both of them toxic and are not good for you what mean you shout not drink redbull every day or priworkut
Cyanocobalamin his crap make me sick every time I take any thing with this in it
monster drink vatamin water has it they both make me sick . and walgreen vatamins have cyanocobalamin also get really sick to my stomch ya my body does not like it at all
Can anybody help me?
I understand what you going through, I suffered hypothyroidism for 18 years, I was able to beat hypothyroidism with pure natural root and herbal supplement no surgeries. Thanks to dr isibor on youtube
Hello x
B12 shots causes early morning awaking 3 am every day. I lost my peaceful sleep with these shots
You may just need to adjust your dose.
Take magnesium supplements at night
Methyl with hydroxy cobalin global healing 5000mcg liquid b12 45 bucks for 2 Oz but it's worth it very good brand
I’m doing the exact opposite
Of what your saying.
Your just throwing around big words