Coagulation Cascade - Easy Way To Remember Intrinsic vs Extrinsic Pathways | PT or PTT?

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  • Опубліковано 31 гру 2024

КОМЕНТАРІ • 144

  • @PiyushKumar-lg9is
    @PiyushKumar-lg9is Рік тому +66

    Play table tennis and play tennis, what an excellent way to remember diagnostic tests. Amazing clear and concise information

    • @RhesusMedicine
      @RhesusMedicine  11 місяців тому +5

      Picked that one up in Medical School, has stayed with me!

  • @icymoorge
    @icymoorge 4 роки тому +248

    This video is very good. Clear, gives good mnemonics, I feel like I remember everything, I will be back in a few months when I forget it all again

  • @nilsboller4651
    @nilsboller4651 7 місяців тому +15

    You can remember Via-K-Ant with the year 1972 (10,9,7,2)

  • @clieolada3601
    @clieolada3601 9 місяців тому +8

    Calcium is not Plasma Factor V, but IV. plasma factor V is labile factor/proaccelerin

  • @yadums1448
    @yadums1448 Рік тому +12

    This was about 2 hours of reading compressed to 6 minutes. All the needed points and mnemonics .tysm

  • @RhesusMedicine
    @RhesusMedicine  4 роки тому +6

    Buy Us A Coffee!: www.buymeacoffee.com/rhesusmedicine
    For more medicine videos consider subscribing (if you found any of the info useful!):
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    Video Timestamps:
    0:00 Intro
    00:27 Intrinsic vs Extrinsic Pathways
    00:57 Common Pathway
    1:37 Easy way to remember intrinsic vs extrinsic pathways
    2:08 What is the difference between PT and PTT?
    2:48 What are the Vitamin K dependent clotting factors?
    2:55 What causes a prolonged PTT?
    3:09 What causes a prolonged PT?
    3:30 What causes a prolonged PT and PTT?
    4:04 Where in the coagulation cascade do different anticoagulants work?
    5:45 What are the antidotes to anticoagulants?
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  • @JK-jd1ir
    @JK-jd1ir 3 роки тому +41

    This helped me recap the coagulation cascade for post-graduate exams. I especially liked how you included the clinical side of things with the blood tests and medications. Keep it up!

  • @K1312-s8d
    @K1312-s8d Рік тому +3

    As an emergency doctor, this is an excellent recap of the clotting pathway and the relevant drugs.

    • @RhesusMedicine
      @RhesusMedicine  11 місяців тому

      Thank you, appreciate the feedback!

  • @chibzyt5699
    @chibzyt5699 Рік тому +2

    BRILLIANT BRILLIANT BRILLIANT video. The effort and ease for everyone you considered is just heartwarming. Really love this video.

    • @RhesusMedicine
      @RhesusMedicine  Рік тому +1

      Thank you for the feedback, and for watching! 😊

  • @dumisanzama3901
    @dumisanzama3901 7 місяців тому +5

    Vitamin K dependant factors: "1972 was the disco era" (1=10) 9,7,2 and diSCo=protein S&C) this has worked for me instantly after I had tried and failed to memorise them. I would always confuse them and would sometimes mix up the numbers after some time.

  • @FishoeShoe_da_great
    @FishoeShoe_da_great 7 місяців тому +5

    that tennis mnemonic is just beautiful

  • @gagagig2895
    @gagagig2895 3 роки тому +5

    Awesome! I try to read this topic by myself for half a day and still confusing but u make it clear in 6 mins. Thank you so much.

  • @krutika8656
    @krutika8656 3 роки тому +13

    So beautifully explained!! And you guys have managed to cover everything, in such a short time!! Thank you so much for this video! :) :)

  • @jamiuadebiyi6778
    @jamiuadebiyi6778 3 роки тому +3

    This is the best video on clothing factors so far.Thank you

  • @adamwalsh1977
    @adamwalsh1977 2 роки тому +1

    Ur am you so much you make a complex algorithm more simple & REALLY liked the mnemonics. It’s the best way I learn & they defo stuck 👍🏻

  • @abdu_jilani
    @abdu_jilani Місяць тому

    Greatest video on the coagulation cascade!

  • @wael9704
    @wael9704 11 місяців тому

    Fantastic video! Love the clinical correlation and drug action mechanisms. Perfect for post-grad exams. V nicely done.

  • @rgvn5
    @rgvn5 2 роки тому +27

    Ninja nerd taught me an easy way to remember: Intrisic pathway = 12 11 9 8, Extrinisic = 7 3, common pathway = 5 2 1
    Put 10 in the middle.
    Intristic pathway you count down except 10
    Extrinisic path way 7 + 3 = 10
    Common pathway 5 * 2 * 1 = 10
    Now you will never forget again

  • @razanabdullah1016
    @razanabdullah1016 3 роки тому +3

    Clear, simple ,short and highly informative 👏🏼👏🏼👏🏼👏🏼 thanks

  • @viona8897
    @viona8897 Рік тому

    I just want to say a big big big thanks.
    I especially enjoyed the memory aids- really amazing!

  • @allisonsouter9589
    @allisonsouter9589 Рік тому

    best video I have seen yet on this topic, thanks so much

  • @arnavupadhyay5970
    @arnavupadhyay5970 4 роки тому +3

    Really covered it all in so less! Great work!!

  • @naveenkumar9215
    @naveenkumar9215 9 місяців тому

    This video really helped me now! Thanks a lot for your contribution for medical education!

  • @bakindeakindapo9618
    @bakindeakindapo9618 Рік тому

    From the bottom of my heart, Thank you so much. I really really appreciate your explanation.

  • @lorifondren5583
    @lorifondren5583 Рік тому +1

    This video is absolutely AMAZING! Thank you so very much for sharing it with us.

    • @RhesusMedicine
      @RhesusMedicine  Рік тому

      Very glad it was helpful, thanks for watching :)

  • @maisaaabuwasel6040
    @maisaaabuwasel6040 8 місяців тому

    what an amazing video! great explanation and very helpful memorizing tools!

  • @pakchess69
    @pakchess69 2 дні тому

    What a bloody legend I have an exam in 2 hours and I will not forget table tennis

  • @zackabdihakim2737
    @zackabdihakim2737 Місяць тому

    Amazing lecture. Thank you very much.

  • @ICU_NERDSE
    @ICU_NERDSE Рік тому +1

    you are so brilliant ! Thank you for this!!!

  • @rahulkumar-wf1dd
    @rahulkumar-wf1dd 3 роки тому +3

    Been through a lot of videos, in search of this topic, it couldnt have been better 🙏
    Posting it at 3.45 a.m, my exam is in next 4 hours,
    Thank you

    • @RhesusMedicine
      @RhesusMedicine  3 роки тому

      Thank you Rahul, the feedback means so much! Crush that exam- best of luck! 💪

    • @jaymorgan.
      @jaymorgan. 2 роки тому +1

      Did you pass? This topic is still confusing to me. Lol

  • @shadysid5570
    @shadysid5570 Рік тому

    Wow, this video has every bit of information I needed

  • @OmnipotentO
    @OmnipotentO 8 місяців тому

    Really nice "cheat sheet" style layout. Very useful

  • @seadimogladness2461
    @seadimogladness2461 5 місяців тому

    Tennis mnemonic is really helpful. Thank you

  • @theanonymouspotato1924
    @theanonymouspotato1924 11 місяців тому

    i'm not being dramatic when i say this video probably saved my life

  • @monicag918
    @monicag918 2 місяці тому

    This video is amazing!!! Thank you so much

  • @wellermasong6984
    @wellermasong6984 2 роки тому

    Thank you for this. Brief and concise. God bless!❤

  • @DrPBaptiste
    @DrPBaptiste 4 роки тому +6

    Not an easy topic to cover but you've done it really well!

    • @RhesusMedicine
      @RhesusMedicine  4 роки тому +1

      Thanks Dr Baptiste, I appreciate that! Hopefully provides an all in one video for people to come to for a refresher

    • @DrPBaptiste
      @DrPBaptiste 4 роки тому

      Rhesus Medicine yes it was good for me!

  • @JesúsEduardoPalaciosLópez
    @JesúsEduardoPalaciosLópez 3 місяці тому

    We should share this way of rememebering important topics

  • @MommaBearsCorner
    @MommaBearsCorner 18 днів тому

    tks for explaining this so well.

  • @angrygunther2569
    @angrygunther2569 3 роки тому

    Excellent video! I really love these mnemonics.

  • @dskim24
    @dskim24 Рік тому +5

    That first sentence you open with; yup, hence I'm here.

  • @alexahmed2581
    @alexahmed2581 Рік тому

    simplified and explained very well thank you!

  • @alexandradelliou
    @alexandradelliou 6 місяців тому

    This is your first video that I watched. SUBSCRIBING!

  • @bivoist
    @bivoist 9 місяців тому

    Thank you so much. This nice explanation helped me alot.

  • @ritikasrivastava4084
    @ritikasrivastava4084 10 місяців тому

    U r best all in one helps 🙏🙏🙏

  • @DrAmmanuel
    @DrAmmanuel 2 роки тому

    Very helpful , especially the tenis mnemonic

  • @elpedro812
    @elpedro812 3 роки тому +2

    It's very helpful and very well explained! TY

  • @gabrielehiraoka4853
    @gabrielehiraoka4853 Рік тому

    Thank you for this video! Studying for hematology for my lab tech exam and this video really helped

  • @lammeesakc867
    @lammeesakc867 Рік тому

    Thankyou for these❤

  • @ortaekvator
    @ortaekvator 10 місяців тому

    Harikaa çok teşekkür ederim. Kanalın ilerleyiş biçimini de çok beğendim emoji kullanmanız odaklanmayı kolaylaştırıyor. Arkadaşlarıma önereceğim inşallah❤

  • @FelixNgoge
    @FelixNgoge Рік тому

    Thanks am from long holiday this context has really recaped. My mind

  • @dr.leelaram
    @dr.leelaram Рік тому

    Great lecture❤

  • @rebbekandahuma2173
    @rebbekandahuma2173 Рік тому

    Awesome! Thank you❤️

  • @wajeehashah7103
    @wajeehashah7103 3 роки тому

    Awesome video thanks dudes

  • @michellegordon3319
    @michellegordon3319 3 роки тому

    Informative, thorough and to the point. Thank you 🙏

  • @hanisofiamazlan794
    @hanisofiamazlan794 Рік тому

    Love it, thank you so much

  • @jazzygirl160
    @jazzygirl160 2 роки тому

    thank you this helped me differentiate between all 3

  • @shinigglory3689
    @shinigglory3689 3 роки тому

    Thanks for this informational ❤️❤️

  • @tejasmahajan1557
    @tejasmahajan1557 7 місяців тому

    Nice explanation

  • @АлександрМуравский-з3ю

    Omg. Thx very much ❤

  • @dumindasamarawickrama3795
    @dumindasamarawickrama3795 9 місяців тому

    Great work

  • @ReyShen-tv3xj
    @ReyShen-tv3xj Рік тому

    hello, I thought LMWH didn’t really have a reversal agent, which is why heparin is preferred in critical care situations

  • @curelord
    @curelord Місяць тому

    very good 👍

  • @ameliamorton1686
    @ameliamorton1686 Рік тому

    Thank you God bless

  • @alangoomez
    @alangoomez 9 місяців тому

    Thank you ❤

  • @timothywiebe4714
    @timothywiebe4714 2 роки тому

    Great one! TY

  • @nagatsatti8426
    @nagatsatti8426 3 роки тому

    Thank you very much doctor

  • @EJTDB
    @EJTDB 2 роки тому

    You are magnificent! I will never forget this!

  • @aamirmuhammad7962
    @aamirmuhammad7962 3 роки тому

    Wow amazing 🤩

  • @macsuip2
    @macsuip2 Рік тому

    Good job

  • @stevebradford3939
    @stevebradford3939 Рік тому +1

    its very easy to forget.

  • @marine-se2vl
    @marine-se2vl 11 місяців тому

    great video

  • @bryanamante7532
    @bryanamante7532 4 роки тому

    👏 Amazing. Thanks!

  • @jacquelineparadzayi5859
    @jacquelineparadzayi5859 3 роки тому

    Amazing 👌simply amazing

  • @swatimishra697
    @swatimishra697 4 місяці тому

    THANK YOU :)

  • @sheliceallen68
    @sheliceallen68 3 роки тому

    Can you give an example of injuries that would release contact activation or cause tissue factor to be released?

    • @RhesusMedicine
      @RhesusMedicine  3 роки тому +1

      Hi Shelice! Generally speaking, we'd mainly be looking at trauma- which is of course a situation where coagulation would be a physiological attempt to reduce blood loss.
      There are of course others, but there are technical differences. Endothelial dysfunction, for example, may result from many causes including smoking, hypertension, diabetes mellitus, dyslipidemia etc. Endothelial dysfunction has been shown to contribute to the pathogenesis of thrombosis, but this is more of a pathological process rather than a physiological process seen in response to trauma!
      Hope that helps somewhat. Thanks for watching!

  • @JzQ21
    @JzQ21 4 роки тому

    Thank you so much!

  • @A.2.0.2.4-5
    @A.2.0.2.4-5 3 роки тому

    WONDERFUL.

  • @nonyeonochie3250
    @nonyeonochie3250 Рік тому

    Perfect!!

  • @sabaamjad632
    @sabaamjad632 Рік тому

    why i saw this so late ALSO please mention heparin monitoring is done by APTT n why?

  • @kenp2396
    @kenp2396 2 роки тому

    Is platelet factor 3 the same as tissue factor/factor 3?

  • @janaadham9011
    @janaadham9011 Місяць тому

    Brilliant

  • @reagananesthetist-ss4bh9wr9

    Fantastic

  • @stacymethvin3426
    @stacymethvin3426 3 роки тому

    Thank you ! I needed this for my exam tomorrow and yes....I will be back as well, but the calcium Ion is Factor IV, not V. Just so you can make the change.

    • @RhesusMedicine
      @RhesusMedicine  3 роки тому +1

      Hi Stacy! Thank you! (Also for the coffee!! 😁). I'm so glad it helped - as for the Factor V, you are absolutely correct that Factor IV is a calcium ion, in the video I say that Factor V is needed alongside a Calcium Ion, I can see however how it could cause confusion as they're listed together- I should have made it clearer! Thank you again for your support, it really means a lot. All the best with your exam :)

  • @ephraimjosephfalcunit5768
    @ephraimjosephfalcunit5768 3 роки тому

    damn, that was good! thank you!

  • @hk6474
    @hk6474 2 роки тому

    Good sheet

  • @sohanirahman720
    @sohanirahman720 10 місяців тому

    Tissue factor II is inhibited by heparin

  • @09ch03
    @09ch03 3 роки тому +1

    hey the calcium is factor IV
    na

  • @jamalazmat9617
    @jamalazmat9617 24 дні тому

    Tennis excellent

  • @kenp2396
    @kenp2396 2 роки тому

    My professor says run(one) to(two) the five and ten store.

  • @switchblade8028
    @switchblade8028 3 місяці тому

    Just wow

  • @gem270
    @gem270 4 роки тому

    Thanks. It’s starting to click

  • @dianneloma9047
    @dianneloma9047 Рік тому

    idracizumab or idarucizumab?

  • @samjones1320
    @samjones1320 7 місяців тому

    I love you

  • @zux1153
    @zux1153 4 роки тому +1

    👏👏👏👏👏

  • @andycheng2191
    @andycheng2191 3 місяці тому

    SN0T makes your Vit (K)LOT. Seven, Nine, 10, Two (SNOT)

  • @zahidhussain_8
    @zahidhussain_8 Рік тому

    Rhesus monkey😎

  • @JiminFanx
    @JiminFanx 2 місяці тому

    Thank you 💘💘

  • @wiamalbouzidi7778
    @wiamalbouzidi7778 2 роки тому

    Thank you so much !

  • @tonythomas55
    @tonythomas55 2 місяці тому

    Good job