Coagulation cascade | Human anatomy and physiology | Health & Medicine | Khan Academy
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- Опубліковано 26 вер 2024
- Created by Patrick van Nieuwenhuizen.
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I studied Robbin's pathology, I studied guyton and believe me, these 14 minutes have stood more valuable for me than those 20 pages of textbooks
Exactly! Those who really know how complicated this whole coagulation thing is have great respect for this presentation. Of course, this presentation is targeted towards an entry-level allied health students: nurses, paramedics, respiratory therapists, etc. I am a nurse (now retired, thank God) with an extensive background teaching allied health students, and many years of experience in ICU, PACU, ER, and Med-Surg. and I’ve forwarded these coag. videos to colleagues who’ve enjoyed them as I have.
World needs more teachers like you...
Nicely broken down and very easy to follow! I swear, I spend an hour just trying to read about this stuff, but watching a 15 minute video and I completely grasp the concept now! Thanks a lot!
"lets say you weren't very good at counting" omg that entire part brought my sides into orbit
I felt less dumb after watching this video, my lecturer talked like a machine gun
our lecturers always have
10 years out of college and I tried to learn it in multiple occasions from so many different textbooks and you did it in 14 minutes. Thanks 🤣😍
Studying this cascade from the pov of different subjects at college and never been able to carack it doen like today
honestly, after the complement system this is like a walk in the park
It's the opposite for me? But this was still pretty easy to understand. Guess it depends on who u r learning from as well
@@gh-ps5es how is it easy for you I am dying trying to learn them 😂💔
Been studying this sh*t for ages and you taught me the easiest way to remember it! I like how you said about the numbers (factors) ultimately leading to the 'goal.' And yes it worked for me because I'm bad at counting lmao
A living legend...man u dont know how much u help...i can only say God bless u
It's just wonderful how you organize notes so that it can be easily remembered! Love your videos!
Extremely clear explanation!! amazing
I’m about to cry this video helped me more than I could imagine
This was fascinating. I am learning about anti-coagulants in nursing school, and this really helped me with the foundation as to WHY we bother with PTT, PT/INR lab values. Thank you!
Thank you very much sir .. Thats how medicine should be explained to doctors .. 👍
This was amazing! I was struggling to fully understand my uni lecture on coagulation but this video made it so much easier by going thru the steps diagrammatically and vvv simply! v relevant + to the point too, no waffle!!
Fell in love with the explanation, its saving the life out of me. Thank you sm❤️❤️❤️
You have helped me understand this thru the past several months. It took a while, but it's all coming together. Thank you.
God bless you!! You explain this so well and oh my gosh I needed this!
Best best vedio on coagulation cascade I've come across
This is very helpful and easy to understand ,also loved the tricks to memorize it better
Omg …. This video is so good. I had to pause it halfway to give a thumbs up and comment. I am phlebotomist, and I have been wondering how anti Xa works. With all the video I have gone through online. This video, I believe is the best. The cascade is well explained with tricks to help me remember. I will love to explain to some of my patients this amazing biological process in our human body. Thank you for this amazing 🤩 video 🙏
thanks! I have to study 140 pages of notes on anticoagulant, anti-platelet, and fibrinolytic drugs. This is going to help me a bunch.
No way i can describe how much of a great helpful and intelligent human being you are
"Assuming you have those friends" LOL
Lol. I can relate
This is the absolute BEST video I've watched on intrinsic/extrinsic pathways! Such a clear understanding now! THANK YOU!
This video deserves noble prize in education
Videos like this make me love UA-cam. Great job! I loved the visuals.
Almost a decade later and still the best video on the net to learn clotting factors
One of the best coagulation videos out there!
omg, you are my hero, god bless you, im gona smash this knowledge right to my profesor face, thank you so much!!!
Easiest way to remember it, thank you so much!
Most beautifully explained - thank you!
This was so so very well explained!
And I love the little things to help us remember it!
Thank you. This was much easier to follow than the first two I watched.
such a good teacher. thanks for making this!
Great video, greetings from Colombia Armenia U. Humboldt
this was beautifully done. it made so much sense. if my lecturer only showed this video instead of talking for an hour
"...while evolution was designing us". Wow! Such an intelligent designer evolution is. How people can believe this masterpiece just came together with no design is beyond human comprehension or reason.
They're stubborn
I thought the same thing! Such a betrayal of their own beliefs to personify a seemingly meaningless and random process!
this is amazing...you are God's sent. my teacher makes it look so complicated...
best video? no best video EVER!!!
I tried to learn this a couple of years ago for my exams and I must confess, I could not answer the question. Listening to this video and watching you create such a complex concept so simply is so good, thank you
Wow this explanation was amazing
Just Khan Academy saving the day again. thanks!
Brilliant Lecture.
The best explanation I ever had in coagulation cascade I wish you where our lecturer 🥹
amazing... i am an egyptian vet and i love your videos so much 💙💙💙
thank god for this channel... about to singlehandedly save my degree!!
I clicked on your video by accident. But your video and explanation skills were so good, I subscribed. Thank you for the information, this is great!
I alway look for videos from Khan academy .. always useful .. many thanks ❤️
you just explained in 15 minutes what my lecturer failed to do in 3 hours
Thanks for existing
This video is an A for brilliant explanation
i just love the way you teach along side how to remember it. i wish my teachers were like this! :/ thanks
It's not easy getting your head around this but you did a great job of explaining all the pathways. Thanks.
"you'd become one large walking clot" HAHAHAHAH
Brilliant delivery. Thank you!
it's REALLY helpful, thanks.
Zymogen forms are one of the most amazing things in the body, in my view. Your body is locked and loaded to do so many things, it's very efficient. Especially in this case, when something soluble is turning into something insoluble.
Wow - great little story to remember the factors :) thanks!!
wow this video is super good! im gonna leave a comment here!
...and then i saw who published it; OH! KHAN! i knew it. thanks khan academy ;)
Great help. Big thanks
thank you Patrick for the very informative lecture :)
Seriously, this video is amazing.
Great explanation!
Very simple to understand it by these little cute drawings .
Thanks a lot .
Clotting factor 2 is actually Prothrombin, not thrombin. Thrombin is 2a. Great Video!
Thank you so much for your efforts in doing this video!! God bless you
thank you so much for this video, so easy to follow
such a clear simple explanation thank u!!
Thank you for the excellent lesson. The amplification sequence explanation (07:16) was very helpful in understanding the significance of the activation process.
this literally just rewired my whole brain
it's just awesome! you simplified it like a boss
U made it so easy
Helpfull in understnaging and memorizing too ...!!! Thank you ....!!!
You made this sound so easy and it made so simple to understand. Thank you so much!!!
this guy is just awesome..
you have just saved me !!! thank you so much for the video
im so happy i found your page!
this video is gold
Great summary, really useful; but you said the first step would be the platelets aggregating to the site of injury, but wouldn't the first step be vasoconstriction? This would significantly slow down the blood flow
I think it is because he is talking only about the clotting cascade with platelets and such, even though that would be the first part.
obviously...
@@user-rj8wm8oj1c If it was obvious then why bring it up? A little bit of a contradiction here lol.
Three years too late.. but vasoconstriction will be the first thing to occur in PRIMARY hemostasis. The coagulation cascade occurs in SECONDARY hemostasis. He shouldnt have worded it that way, but for this portion of hemostasis it makes sense.
I love you and this video, thank you so much
Thank you so much, I always come in this channel for help and you guys never disappoint me
Thank you!
Wow! You really helped me learn this material. I was so confused by my professor. Thank you !!
Thanks for this amazing explanation!!
Really helpful thank you!!!
You did such a magnificent work over here
Well done
Incredibly helpful! Thank you!
so good thanks
Loved this.
What a great video. Thank you :) I would love to see a video like this and include how heparin, Coumadin, aspirin, etc works on this pathway. :)
yup
+Katelin Gates Subscribe to my channel, I will be posting the cntent in a matter of moments
That would make this video pretty lengthy and kind of long shot. Aspirin inhibits formation of TXA2 (thromboxane2) which is part of the primary hemostasis process. Coumadin inhibits epoxide reductase which activates Vitamin K. Vitamin K is necessary for gamma carboxylation of factors II, VII, IX, X and proteins C and S. And heparin inactivates thrombin (IIa) and Xa through another mechanism known as antithrombin dependent mechanism..
Maybe in a different video it would be helpful
Katelin Gates ]b
Thank you
This is exactly what I'm looking for! This is very helpful!
Fantastic. This is just incredible. Great job.
Thank you so much for your great videos! I got a better grade on my midterm from watching your videos!
This was so helpful! Thank you so much.
Wow, thanks! My lecturers are shit! You explained in 15 minutes what my lecturer could not in an hour.
What's heparin? I hear that comes into play when breaking down a clot or something.
Heparin is basically a natural anti coagulant protein . Natural because is made in your body. You can use it before performing a cannulation , you put some heparin on the tip of the needle to prevent blood clots from forming and eventually close the tip of that needle, which would make injecting drugs into the vein harder.. :P
Heparin promotes Antithrombin 3 (a serine protease). Antithrombin 3 inactivates Factors 2 and 10.
Doktor One True, only heparin is NOT a protein but a GAG (glicoseaminoglican) polymer.
PonzooonTheGreat it's an anticoagulant made by liver which keeps the blood in liquid form when the blood capillaries are not hurt
Does Prekallekrein and HMW Kininogen also includes in the intrinsic pathway? Please explain anyone. Thankyou.
This was tooooooooooooooooooo good!!! Thank you so muchh
Thank you. Really made a big difference 👏🏽
This video is pretty good, thank you so much really