I cannot believe how simple it actually is but our presenters made such complicated annotations with confusing markings and an unwelcoming font. This was great!
All the years Iv been studying and scouring the internet for little bits of simply put explanations, this is one of the nicest and easiest videos to follow. I'm not one to usually comment on things, but I feel like this deserved a big thank you! Love the videos, please keep it up! :-)
I could not understand Coagulation Cascade for long time but your tutorials which is long just 4 mins can make me clearly understand and also I can remember it. Thank you so much.
Hello there! I'm back after 5 years. I used to watch your video and incorporate it whenever I study back in college. And all of them helped me a lot. Thank you so much. God bless! *i always fell asleep whenever I read the whole chapter of the book, so this video saved me from all the reading that usually don't get into my mind*
Your Tutorial was one way helpful but at the same time you have forgotten I think.. That Factor 7 in the extrinsic pathway and Factor 9 in the intrinsic pathway require Calcium ions as their cofactors for the activation of the respective factors in their respective pathways.. :) :)
They are just wonderful and especially for the undergraduates and postgraduates as well, just keep it up and keep posting more and more ...thanks once agasin
you forgot to include the factors that requires calcium ions to get activated. that's pretty much important though! so, in this case; i would add calcium with factor VIIIa to activate factor X, and would add it as well with factor Va to transform prothrombin to thrombin. In addition, i guess that u miss that VIIa in the extrinsic pathway can activate IX to IXa. Otherwise i like ur simplicity.
Great presentation for lay person like me. I heard that Ca++(IV) is not considered a special factor as it is abundantly available around. Please correct me if I were wrong. Regards
Basically it rains down Roman numerals until Prothrombin get converted to Thrombin. Then fibrinogen converts to Fibrin mesh (which all the platelets and crap stick to). Got it. Ty.
can you tell me if you have a video about the antagonists and the agonists and about the different receptors like endogene agonists. thanks a lot for your helpful videos :)
You didn't mention that the thrombin produced in the extrinsic pathway is not enough to activate conversion of fibrinogen to fibrin. The extrinsic pathway only enables the activation of intrinsic pathway from which you can generate enough thrombin to produce fibrin. Pretty important step to mention 😬 I do really like the style of the videos though :)
After watching this vid it's easier for me to understand now and I realized that our teacher made mistake about the the extrinsic and intrinsic pathway's😬
This is a good video for someone new to the Coagulation Cascade but... You didn't add the HMWK and prekalikrein in the video. Both of which are part of the intrinsic pathway. You also didn't include Factor XIII (Fibrin Stabilizing Factor), in the presence of calcium, stabilizes factor Ia or soluble fibrin monomers into a insoluble Fibrin polymer. Other than that, it's good. :)
Has anyone told you that you sound a lot like Stewie. Cause - you do. And when I realized that you do whilst listening to your vid. I start to giggle a bit. I do apologize :< but thanks for these great videos. :)
![Lp. Сердце Вселенной #60 РОЖДЕНИЕ ЛОЛОЛОШКИ [Финал] • Майнкрафт](http://i.ytimg.com/vi/YoR0pAV9FVQ/mqdefault.jpg)
I cannot believe how simple it actually is but our presenters made such complicated annotations with confusing markings and an unwelcoming font. This was great!
a
you are right
I saw this video 9 years , back then I had just entered med school..
Now in 2023, im watching it again for my MS exam...
Time flies...
Thank you
All the years Iv been studying and scouring the internet for little bits of simply put explanations, this is one of the nicest and easiest videos to follow. I'm not one to usually comment on things, but I feel like this deserved a big thank you! Love the videos, please keep it up! :-)
I could not understand Coagulation Cascade for long time but your tutorials which is long just 4 mins can make me clearly understand and also I can remember it. Thank you so much.
Simple, directly to the point... I love it
that's what's missing in our classes
THANK YOU SO MUCH!!! People really make things harder than what it is! I saved so much time watching this video!
I watched literally 2 hours of videos before I FINALLY FOUND ONE I UNDERSTOOD! THIS ONE! THANK YOU!
Hello there! I'm back after 5 years. I used to watch your video and incorporate it whenever I study back in college. And all of them helped me a lot. Thank you so much. God bless! *i always fell asleep whenever I read the whole chapter of the book, so this video saved me from all the reading that usually don't get into my mind*
This is just perfect! Thank you for clearly explaining what my textbook couldn't do
I have watched countless videos trying to grasp this concept in time for my exam and this was by far the easiest to remember.
Your Tutorial was one way helpful but at the same time you have forgotten I think.. That Factor 7 in the extrinsic pathway and Factor 9 in the intrinsic pathway require Calcium ions as their cofactors for the activation of the respective factors in their respective pathways.. :) :)
Ravindranath Kamath right it's written in my book , but really he is amazing in explaining
I was thinking the same thing the factor 7 was helped by factor 3 and Ca2+ so it converted into 7 a, well its okay tho he can forget about something
Thank you
They are just wonderful and especially for the undergraduates and postgraduates as well, just keep it up and keep posting more and more ...thanks once agasin
don't know what any of this means, i just memorized the entire video 🙌💁
Thanks 😊.
I can't tell you
How much easy you make this for me :)
Best tutorial I've seen so far! Thanks a lot!
Dude, you killed that. Well done
This is great. I need to present this in class and this video helped me a great lot in summarising all the info I read, much thanks :)
Whose amazing idea was it to denote this cascade using roman numerals? /sarcasm
Yeah, it's like it could not be anymore convoluted if you tried really, really hard.
pretentious scientists probably lol
...Probably to differentiate it from the complement cascade that uses Arabic numerals?
How stupid are you that you can't read Roman numerals?
My professors did the thing too probably to differentiate it and so it'd help you when you're actually try to remember the scheme
you have the best tutorials online!
These are so useful and clear. Thank you very much!
The best explanation so far
this guy has the same voice as that curly haired chef tutorial guy on the food network. love it
Very super explanation actually ur vedio is more effective than others
Thank u .... This was simply Awesome..... Undesrstood the thing in just 4 mins !!
you forgot to include the factors that requires calcium ions to get activated. that's pretty much important though! so, in this case; i would add calcium with factor VIIIa to activate factor X, and would add it as well with factor Va to transform prothrombin to thrombin. In addition, i guess that u miss that VIIa in the extrinsic pathway can activate IX to IXa. Otherwise i like ur simplicity.
This is the Most important comment I was replicating my teachers work and was missing that
This was wonderful! Thanks! You must continue the good work!
this is the best, short but brief. Thanks a lot
Great presentation for lay person like me. I heard that Ca++(IV) is not considered a special factor as it is abundantly available around. Please correct me if I were wrong. Regards
you miss Ca but it's ok, but still a good work :)
I appreciate your work! It is so so so clear~
Amazing explanation
Thank you for your help. I have a question
What is the role of calcium in coagulation
Basically it rains down Roman numerals until Prothrombin get converted to Thrombin. Then fibrinogen converts to Fibrin mesh (which all the platelets and crap stick to). Got it. Ty.
can you tell me if you have a video about the antagonists and the agonists and about the different receptors like endogene agonists. thanks a lot for your helpful videos :)
Please can you update to do new cell based model? Intrinsic and extrinsic aren't taught anymore...
thanks immensely for making it sooo simple!
He baghwan... Sab sirr ke upar se nikal gaya....
You made it very simple for me, thanks
Very good video sir ....thank you sir....sir please send videos on all topics of biochemistry and physiology
Very helpful thank you! I was struggling with my med class notes.
comprehensive. Awesome and really helpful. Thanks a bunch tutor
What initiated factor 12? Is it in active form always? Thanks
HMWK & Prekallikrein
Thank you thank youuuu i was suffering from it 😂
Tomorrow is my practical exam wish me luck i don't know shit about hematology 🔥💔
Most useful video in coagulation cascade , thx very much
excellent tutorial! very helpful indeed
You didn't mention that the thrombin produced in the extrinsic pathway is not enough to activate conversion of fibrinogen to fibrin. The extrinsic pathway only enables the activation of intrinsic pathway from which you can generate enough thrombin to produce fibrin. Pretty important step to mention 😬
I do really like the style of the videos though :)
thank you
it really makes it too much easier
Thank u sooo much for ur amazing explanations
Thank you so much. This clarified my doubts :)
Thank you for this!📚
Very informative. Thanks a ton!
Does tissue factor activate VII? If not, what activates VII?
Yes
Thank you so much this helped me a lot 🙏.
is there any factor 13 ah??
Love it, but you didn't include factor 13? and calcium
Omg I love this guy #nohomo ..... I have a final tomorow , this is my intervention 💯
Great tutorial sir...👍😃
of great help n I can even wrt it for 1st MBBS paper with other details. I love the wrtn part...its great.
you made it very simple. thanks!
Excellent explanation thank you☺️
thank you. this was very helpful
Such a good tutorial!!
Thank you!! that was so helpful
OMG!! So it was easy like this! thank you soooo much 🥺❤️🩹
it haa been a great vedio.. thank you alot
but unfortunately i have to know their names which is hard to remember
Simple, clear , effective
Where is the factor 4 used (ca++)
YOU SIR ARE AWESOME!
Well explained.. 🎉 thanks..
Woooow thank you sooo much!!! Very helpful! So clear and well explained! Love yooou!! XD
Who attends lectures? I haven't been to one in months :P
After watching this vid it's easier for me to understand now and I realized that our teacher made mistake about the the extrinsic and intrinsic pathway's😬
I can't thank you enough!
thank you!!
Thank you, thank you soooo much 😭😭
This is great, thanks a lot!!
This is a good video for someone new to the Coagulation Cascade but...
You didn't add the HMWK and prekalikrein in the video. Both of which are part of the intrinsic pathway.
You also didn't include Factor XIII (Fibrin Stabilizing Factor), in the presence of calcium, stabilizes factor Ia or soluble fibrin monomers into a insoluble Fibrin polymer.
Other than that, it's good. :)
Nice presentation
You're amazing😘😘 thank you so much 😍😍😘😘
amazing video, thanks
This was great!
JUST AWESOME. THANK YOU.
can anyone explain how do scientists identify all these
Excuse me but you forgot to add factor IX which is needed for stabilizing the fibrin clot and it was activated also by thrombin :)
thank you very much
that was helpful .
That was helpful. Thanks!
Wow its so amazing thank u so much
pray for me so that I'll be a successful doctor in 5 years and I'll donate some money. I'm broke now.
Great video. Thanks!
I think you forgot factor 3 on the extrinsic pathway
factor 3 is the Tissue Factor
Thanks 🙏🏻
Has anyone told you that you sound a lot like Stewie. Cause - you do. And when I realized that you do whilst listening to your vid. I start to giggle a bit. I do apologize :< but thanks for these great videos. :)
excellent one
I really don't know how to thank-you !
Thank you very much !!
This is amazingggggggggg ! Thanks you helped me a lot !! XD
God bless you ❤️
ooooo... time saver ....thank you.
It is OK but u have not discussed about calcium ion
Great video..comment after 8 year
Superrrrrrb sir so helpful
Thankyou :)