Part 7: Microcytic Anaemia Introduction, Iron Deficiency Anaemia, Anaemia of Chronic Disease

In this series we shall discuss the NeedToKnow physiology and pathologies of the Red Cell (RBCs/Erythrocytes)
Part 1: Haematopoiesis - how blood cells are produces
Part 2: Erythropoiesis reticulocytes, erythropoietin, hypoxia-inducible factor, and the structure and function of RBCs
Part 3: Haemoglobin - Structure, Synthesis, and Function
Part 4: Iron Physiology & Clinical Relevance
Part 5: Red Cell Indices
Part 6: Introduction to Anaemia
Part 7: Introduction to Microcytic Anaemia, Iron Deficiency anaemia, Anaemia of Chronic of Anaemia
(other parts pending)
We are currently working on our bank of Need to Know questions, that will support your studies using the recall-consolidate methods detailed in the awesome Make it Stick book
Please like, subscribe, and share our channel with your friends
We aim to created Need To Know content on all the Medical syllabus - if there is a specific topic you have in mind that you’d like for us to cover please leave us a comment below.
Facebook: / need-to-know. .
Instagram: needtoknowmedicine
We are currently working on getting our Free Question Bank launched.
Feel free to leave us any comments/questions below.
NTK Team.
Logo music: www.bensound.com

[@needtoknowmedicine735]

Recommended watching speed: x1.25
00:00:07 - Introduction
00:00:18 - MCR definition of Microcytic Anaemia
00:00:26 - TAILS mnemonic for causes of microcytic anaemia
00:00:46 - Logical way of understanding the causes of microcytic anaemia
00:01:10 - What causes of the microcytosis (small cells) + reason
00:02:08 - Listing the composition of haemoglobin to understand the causes of microcytic anaemia
00:04:22 - What are the 2 most common anaemias in the world?
00:04:43 - Iron Deficiency Anaemia (IDA) introduction + pathological definition
00:04:55 - IDA: most common causes
00:05:22 - IDA: other causes of IDA classified by 3 general causes
00:05:46 - IDA: causes of reduced iron absorption
00:06:26 - IDA: causes of increased anabolic state
00:06:33 - IDA: causes of increased iron loss
00:06:50 - IDA: stages of iron deficiency and why IDA can be both NCNC and MCHC
00:09:01 - IDA: specific clinical features
00:10:06 - IDA: differential diagnosis
00:10:27 - IDA: investigations + explanation of each investigation result
00:14:35 - IDA: the important relationship between ferritin and TIBC
00:15:47 - IDA: management
00:16:47 - IDA: most common cause of failure to respond to oral iron
00:17:14 - Anaemia of Chronic Disease (ACD): introduction + definition
00:17:54 - ACD: causes of ACD
00:18:10 - ACD: also known as Anaemia of Inflammation (AI)
00:18:33 - ACD: pathophysiology of ACD
00:21:30 - ACD: thinking laterally - why does hepcidin synthesis increase in ACD?
00:22:40 - ACD: investigations
00:25:08 - ACD: treatment