Anemia (Types, Findings, Lab Values)
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- Опубліковано 28 тра 2024
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My goal is to reduce educational disparities by making education FREE.
These videos help you score extra points on medical school exams (USMLE, COMLEX, etc.)
For educational purposes only; NOT medical or other advice.
Some videos contain mild profanity and hyperbole solely used to assist with memorization. Viewer discretion advised.
Opinions are entirely my own.
B12 vs Folate: B12 has the #12 for 12 Cranial Nerves so it reminds you that it affects the Nervous System.
b12=b braine
B =bra brain
i dont wanna get all emotional, but i hope u guys are going to make it big in life, i would have never understood this without ur help, god bless u man!
Just wanted to add a little extra to dirty's amazing video. If they show ringed sideroblast, its only present in the bone marrow whereas on a peripheral smear its called basophilic stippling. How i remember it is stiPPling is in the PeriPhery, SideroBlast are in Bone.
One minor correction:
Beta thalassemia unlike alpha is not the result of a a deletion mutation, its a point mutation in the splice site and promoter sequence which results in a reduced synthesis. I've seen this come up as an important distinction between the two types in Q banks.
Also, thank you for taking the time to make these videos.
True
Plz confirm it also please mention if there is any other corrections because we are learning from this video.
@dirty medicine, can you make sure you annotate where the incorrect information are? We don't want to be misinformed.
Sickle Cell Anemia could be listed as another microcytotic anemia.
@@IeAtBulLeTs98 normocytic no?
One minor correction:
The PIGA gene does not code for CD 55 and CD 59, It codes for a surface protein on the RBC, which is anchor for these two!
Specifically the GPI anchor protein!
And also, CD 59 inhibits the MAC.
I can’t thank you enough, the way you make this simple to learn makes me believe that I can make it.
This page is a life saver for medical students before exams
Thank you sooo sooo much! God bless you, this is such a HUGEEEE help to the pathology quiz tom!
Damn, I can only imagine what an AMAZING preceptor you'd be !! Thank you so much for all your videos and helpful tips to remember everything :) You're phenomenal at explaining things !
Thank you so much for this!! Anemia has been such an uphill battle but this really consolidated things so well!!
Nothing short of amazing! Thank you for your videos!
I was chuckling to myself because "piga" in Swahili means to hit/beat, so the CD55 + CD59 slapping the C3 convertase was surprisingly accurate, hopefully that's another memory point! Thanks for summarizing anemias!!
Swahili meds tupo😁
At 6Pm, I get my Heinz ketchup and have a Bite. 6P = G6PD, Heinz bodies, Bite cells. Bonus: Heinz ketchup is red (RBCs).
Thank you! Great video really helped clarify the topics for me!
thanks a million for this awesome video! clarifies alot of confusing concepts
Merci dirty pour vos immense efforts..
Thank you for your wonderful explaining
Perfect timing with this video! We're literally half-way through our heme and lymph pathology module! 😂
to be honest it never made sense until I seen the mnemonics thank you so much!!
Excellent review!
Helpful videos thank you soo much sir
Thank you sir, explained very well👍🏼
Great work as always
Thanks respected sir for such agreat lecture ❤️
I wish I could give another 1000 thumbs up. Thank you!
I have exam tomorrow but dont have enough time to read book so i m watching this video and its pretty much helping me in revising everything .
I wasn't ready 😂😂when he said that Red bloods cells get FUCKED UP.🙊🤭
so minor correction, in thalassemia the problem is not in the heme but in the globin...............huge fan, you have helped me alot................thank you kind sir
Yeah . Genetics of the globulin , a protein
I was bored of studying the slides of anemia😢then i found this..very interesting.subscribed right away❤i love the way of talking😂yoo hide all iron😂..thank you for this video❤
Excellent!
Awsome, thank you👌🏻👌🏻👌🏻
Thank you very very very much..really it’s very beneficial video
Thank you for videos. . I really like the way you teaching; i think you should share more videos 😊
Awesome review!
Very helpful 👌 thanks so much
This was amazing!
Please make a video on Hodgkin and non Hodgkin lymphoma
Recently, I had anemia, or low red blood cell counts, which is common in CLL, and I have CLL.. Red blood cells are needed to carry oxygen to all the cells in the body. With my anemia I experienced fatigue and weakness, and I had pneumonia. My CLL specialist said 'time to treat' as my bone marrow was affected.
There are a million pathoma anemia videos. Do you have a link? Most of the ones I’m finding are difficult to understand the accent of the speaker.
Best explanation...thanku sir ♥️🥰
Great 😌
Great video thanks
Thank You!!!
Thank you so much
Great video thank you
excellent
Good job brother
Thanks a lot... Very helpful 👍👍👍
Thanks!
Imp point in Hereditary Spherocytosis - lacks a central pallor
thank you
Thanks
Thank you tremendously for all these VIDEOS... No lie, I often watch these videos before going to bed! Speaking of which, how would you feel about making a video on SHOCK? Could really utilize some tricks for the various forms of shocks... just a thought
Thanks for this
(Stress) makes me eat (bites) of (favabean) with (Heinz) ketchup
G6pd deficiency
Amazing 🤩
19:36
"heres a red blood cell"
*shows a blue circle*
You're a riot, DM
Thanks sir!
Howel jolly bodies appear in hereditary spherocytosis after therapeutic splenectomy is done so splen function is compromised resulting in howel jolly bodies
Chronic diseases I know could be under microcytic type of anemia, because of increase in hepcidin level which affects the iron absorption
PNH - The H can also stand for Hypercoagulability which shows up as a weird association.
Thank you!!
When you said "our bodies are pretty stupid when it comes to anemia", my Brain took that seriously. 😂
But thank you. ❤
Can you make one for fanconi and diamond blackfan anemia since they're so annoyingly tested on CK?
Thank you so much :)
Wowww.....👍👍
“they’re really quite stupid when it comes to anemia” 😂😂😂
You are amazing♥️
❤thx
Thanks for your video ❤️
Please tell me, is it all anaemia patients that have SS genotype?
Since there are different types, can someone with genotype other than SS be anemic?
You are truly a Gem! dirty medicine
What about perniciious anemia in relation to Zollinger- Ellison?
What happens to the MCV if there is both iron deficiency and B12 deficiency?
Could you please attach the ppt slide?
How about lymphoma pls cover this topic and ANS TOO
At 21:10 you mentioned that C3b causes a MAC to be formed. How does that happen? Is it not C5b and other peptide mediators? That's what it says according to my lectures and Google.
C3b cause it indirectly by initiating the alternating complement pathway and lead eventually to the formation of MAC from c5b and others .
That’s what he meant
@@themusicbasement2542 Oh okay, thanks! Could you maybe provide a link of some sorts detailing this pathway? In my lectures, we learnt that C3b is an opsonin, but then again I'm in first year med so I suppose they don't teach you everything :).
where's the link??
Can you make a video about fanconi anemia plz 😅
Wow i could literally see that fight scene with the cd3😂
The body is not stupid , but we are because still we do not know the reason yet
This video was amazing and you are smart I want you to read more about miracles in this universe created by god like the barrier between the river and the sea in which they never mix once you start read about these miracles You will understand the reason of our existence
If we have to check b12 or folate deficiency... We can get folate and b12 tests... What's the need of homocystein and mma
B12 can show up as normal even when the patient is B12 deficient. Mentioned in another video :)
CRACKS ME UP WHEN HE SWEARS :)))
So I know the Fenton reaction uses iron to make the hydroxyl radical...
I've always thought the hydroxyl radical was very dangerous because to my knowledge there aren't specific enzymes that scavenge/neutralize the hydroxyl radical and it causes a lot of oxidative damage...
Do you think a deficiency in b6 may exacerbate this hydroxyl radical damage?? Because if you have a lack of b6 then the iron can't be used to make hemoglobin so there would be a lot of iron and a lot of the Fenton reaction and a lot of hydroxyl radical formation and oxidative damage???
Does this make sense is there something about this rationale that isn't not accurate or I maybe missing? I begin med school next year I haven the started yet so I have a lot of holes in my understanding of Biochemistry 😕
If anyone knows or has a deeper insight on these processes I’d really appreciate it.... I know high amounts of iron can apparently accelerate aging? I’m concerned that there’s some hole in my thought processes and there’s something I’m missing or misunderstanding about b6 and iron and Fenton reaction metabolism?
Firstly Fenton Reaction is for free Iron that is circulating in the blood, not the one that is overloaded in mitochondria.After this I think your question becomes self explanatory.
Why tf were you watching this when you weren't even in med school
@@abdullahahmad4239 😭😭😭
You saved me. lol. But, seriously, thank you!
I'm in love, u deserve the heaven bro
Haemolytic anemias?
Doesn't c5b form MAC and not c3b? 20:07
How can I donate to you dirty?
💯
goated.
💝📚
Including Pernicious Anemia ????
15:20 go buckeyes
Should have included sickle cell
I think its 2 Alpha and 2 Beta chains and not 4 Alpha chains, needs correction
Lolol
I love you dirty :’j
Thanks