Developments in biomarkers for neurodegeneration in RBD

Aleksandar Videnovic, MD, from the Massachusetts General Hospital, Harvard Medical School Boston, MA, outlines commonly utilized biomarkers in REM sleep behavior disorder (RBD) and highlights recent developments in detecting a diverse range of biomarkers in tissue and biofluids such as CSF and mucosal tissue. He also discusses the need for further research into the detection of blood biomarkers for neurodegeneration, which would enable mass screening for the risk of neurodegeneration within a population. Dr Videnovic also emphasizes the variety of imaging biomarkers under investigation, particularly those used to visualize dopaminergic dysfunction, which appear clinically significant for predicting phenoconversion. This interview took place at the American Academy of Neurology (AAN) Annual Meeting 2024 in Denver, CO.
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