VJNeurology
VJNeurology
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The R4VaD study: cognitive impairment trajectories two years after stroke
Cognitive decline is a recognized risk factor for stroke, as well as a common consequence. Joanna M Wardlaw, CBE, MD, FCRP, FRSE, FMedSci, University of Edinburgh, Edinburgh, Scotland, UK, discusses her study into cognitive impairment rates and trajectories two years after stroke, involving 2500 UK residents. Results showed that around 50% of patients had some degree of cognitive impairment in the initial weeks following stroke. They were found to improve 6-12 weeks after stroke, followed by a gradual decline thereafter. Some risk factors for cognitive decline after stroke were recognized, such as stroke severity and increasing age, however socioeconomic factors such as lower education were not found to be significant in this cohort. Prof. Wardlaw highlights that more research is required into the impact of cognitive decline after stroke with regards to socioeconomic factors, ethnic diversity, and geographical location. Enhanced understanding of risk factors would allow for a more personalized approach to diagnosis and rehabilitation. This interview was conducted at the 10th European Stroke Organisation Conference (ESOC) 2024 in Basel, Switzerland.
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Переглядів: 6

Відео

The debate on the use of EVT for low NIHSS strokes
Переглядів 52 години тому
Wim H. van Zwam, MD, from Maastricht University Medical Center, Maastricht, Netherlands, weighs in on the debate regarding the use of endovascular thrombectomy (EVT) for stroke patients with low NIH Stroke Scale (NIHSS) scores. He highlights that the evidence for treatment is still of low quality and further research in this area is required. He advocates for quick action, especially for patien...
Collecting evidence on delayed reperfusion after thrombectomy
Переглядів 3712 години тому
Adnan Mujanovic, MD, from Inselspital, Bern University Hospital, Switzerland, outlines the challenges of collecting data on delayed reperfusion, noting that imaging does not typically occur in centers 24 hours post-intervention. There are known factors which impact the likelihood of complete delayed reperfusion, such as better collaterals and a lower number of thrombectomy passes. In his recent...
Clinical trials of left atrial appendage occlusion together with anticoagulation
Переглядів 112 години тому
Aristeidis Katsanos, MD, from McMaster University, Hamilton, Ontario, Canada, discusses ongoing randomized clinical trials focused on closure of the left atrial appendage alongside anticoagulation therapy for stroke prevention in patients with atrial fibrillation. It is hypothesized that this combination will result in decreased rates of stroke compared to those who solely received anticoagulat...
Patent foramen ovale: the unresolved questions
Переглядів 92 години тому
Valeria Caso, MD, PhD, FESO, from Santa Maria della Misericordia Hospital, University of Perugia, Perugia, Italy, discusses the key areas that lack data regarding the management of patent foramen ovale (PFO) after stroke. More evidence is needed on the benefits of PFO closure in patients over 60, as growing observational data suggests that there may be a benefit, particularly in patients in goo...
Updates on stroke prevention techniques in patients with atrial fibrillation
Переглядів 182 години тому
Jaime Masjuan, MD, PhD, from The Hospital Universitario Ramón y Cajal, Madrid, Spain, outlines the current approaches to stroke prevention in patients with atrial fibrillation. Anticoagulant drugs are the primary treatment provided to prevent ischemic stroke; however breakthrough strokes can still occur in some patients with atrial fibrillation. Dr Masjuan highlights occlusion of the left atria...
Investigating the effect of a probiotic in patients with Parkinson's disease
Переглядів 11412 годин тому
Proinflammatory alterations at the level of the gut have been identified in patients with Parkinson’s disease (PD), providing the rationale for several studies investigating the use of gut microbiome-modulating interventions. Valentina Leta, MD, King's College Hospital & King’s College London, London, UK, shares details of a double-blind, placebo-controlled, randomized trial that aimed to inves...
Developments in biomarkers for neurodegeneration in RBD
Переглядів 2212 годин тому
Aleksandar Videnovic, MD, from the Massachusetts General Hospital, Harvard Medical School Boston, MA, outlines commonly utilized biomarkers in REM sleep behavior disorder (RBD) and highlights recent developments in detecting a diverse range of biomarkers in tissue and biofluids such as CSF and mucosal tissue. He also discusses the need for further research into the detection of blood biomarkers...
Investigating voluntariness in functional neurological disorder
Переглядів 1212 годин тому
Mark Hallett, MD, from the National Institutes of Health, Bethesda, MD, discusses the underlying mechanisms involved in involuntary movement associated with functional neurological disorder (FND), in particular functional movement disorder (FMD). He discusses the possibility of a paradox with respect to the involvement of voluntary movement mechanisms in producing movements experienced as invol...
Educating healthcare professionals to improve the treatment of functional neurological disorder
Переглядів 1312 годин тому
In this video, William Curt LaFrance Jr, MD, MPH, FAAN, FANPA, DFAPA, FAES, Brown University, Providence, RI, briefly discusses the effort which is being made, both in the United States and globally, to improve education in the area of managing functional neurological disorder using neurobehavioral therapy. By providing healthcare professionals with the the tools and knowledge to address the di...
Save Standard Time: advocating for permanent standard time
Переглядів 612 годин тому
In this video, Karin Johnson, MD, University of Massachusetts Chan Medical School-Baystate, Springfield, MA, briefly introduces the Save Standard Time initiative, which is working at both the state and federal levels to push permanent standard time bills and fight against the implementation of permanent daylight savings time in the United States, due to the negative effects of daylight savings ...
Categorizing ALS to improve trial outcomes
Переглядів 2512 годин тому
The multifactorial nature of amyotrophic lateral sclerosis (ALS) results in different cohorts of patients presenting with different pathophysiology. Jinsy Andrews, MD, FAAN, from Columbia University, New York, NY, highlights the importance of considering this, as clinical trials researching experimental therapies by grouping these patients together have been largely unsuccessful. She explains t...
BRAINs program to promote internal medicine residents’ confidence with assessing neurology patients
Переглядів 1914 годин тому
Prashanth Rajarajan, MD, PhD, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, discusses the Bedside Rounding Alliance for Internal Medicine & Neurology Residents (BRAINs) program, which is being trialed at Brigham and Women's Hospital. This initiative aims to address the unmet neurology educational need of internal medicine residents. As internal medicine residents are often t...
EMBOLISE: middle meningeal artery embolization to prevent the recurrence of subdural hematoma
Переглядів 1714 годин тому
Jason Davies, MD, PhD, State University of New York (SUNY) at Buffalo, Buffalo, NY, discusses the results of the EMBOLISE trial (NCT04402632), examining the use of middle meningeal artery embolization for treatment of symptomatic subacute or chronic subdural hematoma (SDH). The EMBOLISE trial assessed the use of Onyx™ Liquid Embolic System embolization as an adjunct to surgical treatment, compa...
Effects of climate change on neurologic infectious diseases
Переглядів 1514 годин тому
Dr Monica Diaz, MD, from the University of North Carolina, Chapel Hill, highlights the implications of climate change on brain health. As global temperatures rise, hotter summers and shorter winters extend the breeding seasons for disease vectors such as mosquitoes and ticks. This increases the prevalence of infections they carry, such as malaria, particularly in the regions most affected by cl...
Comparing hormonal exposure in late-onset and early-onset Parkinson's disease
Переглядів 1714 годин тому
Comparing hormonal exposure in late-onset and early-onset Parkinson's disease
Skin biopsies for synucleinopathies: key research questions
Переглядів 1314 годин тому
Skin biopsies for synucleinopathies: key research questions
The microbiome in Parkinson's disease onset and exacerbation
Переглядів 2714 годин тому
The microbiome in Parkinson's disease onset and exacerbation
Detecting and preventing secondary brain injury in status epilepticus
Переглядів 1614 годин тому
Detecting and preventing secondary brain injury in status epilepticus
History of investigations into the pathophysiology of FND
Переглядів 514 годин тому
History of investigations into the pathophysiology of FND
The occurrence of refractory migraine in pediatric patients
Переглядів 614 годин тому
The occurrence of refractory migraine in pediatric patients
Growing evidence for sleep and brain health
Переглядів 2014 годин тому
Growing evidence for sleep and brain health
Defining special populations in headache medicine
Переглядів 414 годин тому
Defining special populations in headache medicine
Regulating metabolism in migraine: diet, exercise, and sleep
Переглядів 814 годин тому
Regulating metabolism in migraine: diet, exercise, and sleep
Disease-modifying gene therapies for common epilepsies
Переглядів 1114 годин тому
Disease-modifying gene therapies for common epilepsies
Importance of communication in mitigating the impacts of climate change
Переглядів 1014 годин тому
Importance of communication in mitigating the impacts of climate change
Recent advancements in investigational products for ALS
Переглядів 1214 годин тому
Recent advancements in investigational products for ALS
A biopsychosocial model for FMD diagnosis
Переглядів 1214 годин тому
A biopsychosocial model for FMD diagnosis
The switch to ofatumumab after liver injury associated with ocrelizumab treatment in MS
Переглядів 4614 днів тому
The switch to ofatumumab after liver injury associated with ocrelizumab treatment in MS
The role of HSCT in the treatment of relapsing-remitting and secondary progressive MS
Переглядів 6014 днів тому
The role of HSCT in the treatment of relapsing-remitting and secondary progressive MS

КОМЕНТАРІ

  • @annaburdziej3233
    @annaburdziej3233 Рік тому

    Thank you. You and prof G are incredible despite you dont have the same opinion on some matters. Thank you for this video and precious thoughts ❤ We really appreciate what you are doing for MS community.

  • @kashyappatel3497
    @kashyappatel3497 Рік тому

    Wow! Thank you so much for this video. This has been a long-time coming for my little research group in Canada. Much appreciated.

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