Ep:369 THE SCIENCE BEHIND TREATING INSULIN RESISTANCE IN DIABETES (1&2)

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  • Опубліковано 22 кві 2024
  • TYPE 1 DIABETICS SUFFER AND DIE MOSTLY BECAUSE OF INSULIN RESISTANCE - A TYPE 2 EFFECT CAUSING HYPERGLYCEMIA. ENDOCRINOLOGISTS MISMANAGE TYPE 1 DIABETES HORRIFICALLY. TARGET INSULIN RESISTANCE BY INCREASING INSULIN DOSING AT FIRST IS VERY EFFECTIVE IN HELPING T1DM TO NORMALIZE BLOOD SUGARS AND HbA1c. Our clinical trial in our T1DM patients lowering blood glucose shows improved co-morbidities such as retinopathy, arrhythmias, peripheral neuropathy and cardiovascular events. These insights are not beliefs or conjecture. They reflect real data from an extremely busy clinical practice dealing with metabolic health transition. Know the scientific truth about how your body works. Ask and answer the right questions to optimize your health! Whether you agree or disagree with our content, if we’ve made you think and ask questions, we’ve done our job. Leave comments below.
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КОМЕНТАРІ • 90

  • @ekondigg6751
    @ekondigg6751 Місяць тому +4

    Thanks, and great to hear a mention of Dr Bernstein. His book, although intended for diabetics, is also a treasure of info for everyone in the keto space as well.

  • @robertcywes2966
    @robertcywes2966 Місяць тому +12

    I WISH THE ADA WAS NOT SO CORRUPT AND IT WOULD PROMOTE THESE CONCEPTS

  • @jenn7047
    @jenn7047 Місяць тому +10

    This makes a lot of sense. Glad your patient found you in time to save his eye.

  • @dobrilajovovic-schultz3636
    @dobrilajovovic-schultz3636 Місяць тому +8

    Thank you, I finally understand that i am am obesogenic type. Reduced carbs but not eliminated. Lost 45 lbs but need to do better
    Your explanations are always informative.

  • @my-yt-inputs2580
    @my-yt-inputs2580 Місяць тому +8

    This is something I have discovered about myself. Diagnosed Type 2 in 2011. Was already carb smart by that time. Took Metformin for many years. Around 2018 discovered Keto and slowly transitioned to ketovore. My highest A1c was 7.2. Lowest was 5.7. Over the last several years I've seen my A1C slowly climb back up to 6.3. Occasional cheat. Most or all of my blood markers suggest I am not insulin resistant yet my A1C suggests otherwise. 6ft, 170 lbs. It's not fat related. Liver? I am of the opinion my Pancreas simply is not producing enough insulin. LADA beginning? My current doctor is not smart enough to understand so basically using my own research/knowledge.
    Fasting Insulin, C-Peptide, both good. Trig/HDL ratio less than 1.5(previous was less than 1.0)

  • @michaelrocole7174
    @michaelrocole7174 Місяць тому +9

    Absolute best explanation I have ever heard. Now I am understanding my own situation.

  • @sandymorrison1400
    @sandymorrison1400 Місяць тому +1

    As a paramedic, the "standard treatment" for ALL in crisis diabetics was the same - I was so confused!

  • @LaurieR2255
    @LaurieR2255 Місяць тому +7

    Dr.. Cywes, this was so understandable. Thank you for this. You explained so much to me, tonight!

  • @sandybohon465
    @sandybohon465 Місяць тому +2

    This has way too much common sense for some people. Keep up the good work... :)

  • @brucekendall52
    @brucekendall52 Місяць тому +4

    You are a mountain of information.Thanks.JHB-SA.

  • @alimccoy9132
    @alimccoy9132 Місяць тому +3

    Amazing light from this new information, which has come to us from much more direct, practical research---research that is written down to prove it all! The opponents don't get it. THANKS!

  • @paulheinz2145
    @paulheinz2145 Місяць тому

    You teach us and entertain at the same time, got to love this guy

  • @shelleyhodgkinson1341
    @shelleyhodgkinson1341 Місяць тому +1

    Great explanation!

  • @angies5082
    @angies5082 Місяць тому +1

    Love your passion!

  • @petercyr3508
    @petercyr3508 Місяць тому +16

    You certainly can have type 2 superimposed on type 1 with bad diet and lots of insulin. My dentist is type 1 and has a big belly and all the signs of insulin resistance. He goes berserk when I tell him he needs to be in ketosis as I sit in the chair at age 66 at a slim 135 lbs with an A1C of 5.2. Makes me very sad because I doubt he will see 66.

    • @prestomattwine
      @prestomattwine Місяць тому

      I can’t say what I really want to say, but you’re a jerk!!

    • @tracy3812
      @tracy3812 Місяць тому +5

      @petercyr3508 do you find that even though you’ve turned your life around & maintain it that others dismiss you bec you’re not a doc/APRN etc?

    • @robertcywes2966
      @robertcywes2966 Місяць тому +5

      Share this video w him

  • @vickinewson7710
    @vickinewson7710 Місяць тому +2

    Loved this and shared it on Facebook hoping my parents maybe finally get it 😢

  • @noonchyo
    @noonchyo Місяць тому +2

    Thank you for the clear explanation of obesogenic terminology and how to classify insulin resistant people. Perhaps we should call those folks (of which I am one) "Type 3 Diabetics?" Really one of your best videos. 🎉

  • @ORCHIDLOVER2156
    @ORCHIDLOVER2156 28 днів тому

    That was informative. ❤

  • @mariecampos6923
    @mariecampos6923 Місяць тому +2

    I'm type 1, diy looping setup, a1c since going keto 4.8% - 5 7%. That high was the most recent one as I tumbled off my keto wagon and am having trouble climbing back into the driver's seat. I have the resistance of a type 2 though. And those who are thinking I might have been misdiagnosed, nope, dxd 27 yrs ago, c-peptides were practically non-existent.
    Have to say I like your no bullshite attitude.

  • @MartyRaaymakers
    @MartyRaaymakers Місяць тому +2

    Thanks for helping me get more healthy. 😊

  • @johnallday
    @johnallday Місяць тому +1

    Just found you on UA-cam! Luv your content Doc! Thank you!!

  • @nicholassmith4172
    @nicholassmith4172 Місяць тому

    This makes so much sense as a type 1. I wish I’d see this when I started carnivore and I couldn’t understand why I needed more insulin even tho I wasn’t eating carbs.

  • @marylunney3483
    @marylunney3483 День тому

    Total sense

  • @cherylnelson3815
    @cherylnelson3815 Місяць тому

    Not diabetic, never have been. Current A12 is 5.2….but struggling with intense insulin resistance. It’s been a real roller coaster ride. Thanks to Dr C I understand it better but my brain just won’t adjust to my victory point of ONEderment! 😭 I be been in the 200s for so many years. 😢

  • @elgrandosmokio5418
    @elgrandosmokio5418 Місяць тому +3

    Hi folks greetings from poor Greece

    • @robertcywes2966
      @robertcywes2966 Місяць тому +6

      Greece may be economically poor but it is one of the culturally and most beautifully rich places I have ever visited love Greece

    • @elgrandosmokio5418
      @elgrandosmokio5418 Місяць тому +5

      @@robertcywes2966 Yes sir but I can't afford beef every day and I have to eat pork most of the days. I guess its better than pizza and pasta tho :) Thanks for the love

  • @dryfastingclub
    @dryfastingclub Місяць тому +1

    This is exactly what I've been telling so many people. The title mimics my must popular videos, are you watching my stuff doc??? 😂

    • @johnp7158
      @johnp7158 Місяць тому

      haha powerful stuff ... used your info to literally heal my chronic illness, ty yannick!

  • @UCanHaveHim
    @UCanHaveHim Місяць тому +1

    My glucose, c-peptide and wbc are constantly high. My insulin is always normal. My A1C fluctuates between 5.5-6.

  • @sbcncsu
    @sbcncsu Місяць тому +2

    North Carolina Type 2 since 2017. Keto at first, trailed off and A1C went up. Back on Keto, on a CGM, endocrinologist wants me to inject insulin. Fasting insulin is 19.3 and average glucose on CGM is 162 mg/dl but coming down. Don't want to go on insulin.

    • @robertcywes2966
      @robertcywes2966 Місяць тому +3

      Set up a visit so that we can get you into remission

  • @blsrulz
    @blsrulz Місяць тому +1

    65-99 normal BS, A1c's in the mid-upper 4's. Type 1 can drive down A1C with insulin, but triglycerides go up from carb intake. My A1C in feb was 4.9 type 1 36 yrs. The Dexcom G7 isnt accurate (mine wasn't) #'s were off from glucose meter way more than they closely matched. Eating carnivore weight 205@5'11" (been lifting 40yrs) taking roughly 32u +/- daily. But large protein meals spike my BS so I eat 6 sm meals a day.

  • @jmh8510
    @jmh8510 Місяць тому +4

    T1 here. I cannot seem to get A1c down. 6.4. On carnivore for 7 months my doctor won’t give glp 1 drug. Take about 20 u total ( long acting and rapid ) per day. Help😞. I weight lift, walk. 62 yo female. And 10 lbs to goal weight to 130 at 5’7.

    • @DaveIrish66
      @DaveIrish66 Місяць тому +1

      How do you feel? How are your other blood markers? Triglycerides/hdl ratio?

    • @DaveIrish66
      @DaveIrish66 Місяць тому +1

      Are you low carb?

    • @jmh8510
      @jmh8510 Місяць тому +1

      @@DaveIrish66 great ratio. Yes, low carb.
      I did realize that, believe it or not, reusing syringes for my insulin injections can cause a lot of issues. The old residual insulin inside polymerizes and doesn’t work as well. I’m stunned. The syringes won’t be fully covered by my insurance after June so I was trying to scrounge and reuse the ones I have… But in only using new ones with each injection, the last few days it’s made a huge difference! I’m feeling very ashamed about this🥺. At least my A1c isn’t 12 or anything like that it’s 6.4.

  • @Jayla-dj2gj
    @Jayla-dj2gj Місяць тому +1

    We need thousands of Dr Cywes to treat the massive amount of people dealing with diabetes. I doubt many will be able to find a doctor with this knowledge. If I'm understanding this correctly obesogenic people don't need GLP1 agonist because they already have high insulin and GLP1 increases insulin to bring sugars down???

    • @robertcywes2966
      @robertcywes2966 Місяць тому

      Yes. But in obesity GLP1have appetite suppression effect

  • @darbiz4504
    @darbiz4504 Місяць тому +4

    Why wouldn’t you give Glipizide to a Type 2 diabetic if more insulin is all they need and the pancreas is still functioning? Doesn’t excess insulin as a hormone alter other hormones in the body? I thought Having excess insulin in a type 2 diabetic is what caused them to be insulin resistant?? I am so confused after this video

    • @robertcywes2966
      @robertcywes2966 Місяць тому +1

      Glipizide works

    • @mariomenezes1153
      @mariomenezes1153 Місяць тому +1

      Type 2 diabetes is not really a lack of insulin. It is the inability of the body to use insulin properly to get rid of glucose. In a healthy person, very little insulin is needed to get rid of a large amount of glucose. Once done, the insulin goes back to baseline. The more insulin resist you get, the more insulin is required required to get rid of the same amount of glucose. What this also means is that it will take longer for the larger amounts of insulin to drop to baseline during which time the body cannot access fat stores. Traditional thinking has been to increase the amount of insulin artificially which is like throwing oil on fire considering that the issue is that the body cannot process insulin well. Best course of action is to reduce the amount of sugar (carbs) consumed so that the body does not need to get rid of the glucose. Increasing doses of insulin will get the body deeper and deeper into trouble because it typically means the person is still consuming excess carbs.

  • @HannibalTLC
    @HannibalTLC Місяць тому +4

    At the 17:23 mark, I am wondering if you meant to say you want their blood sugar in 80s rather than 180s? If it is 180, I require more explanation. 😊

    • @robertcywes2966
      @robertcywes2966 Місяць тому +3

      Yes. 80s. 180 is good for my business🤣

    • @HannibalTLC
      @HannibalTLC Місяць тому +2

      @@robertcywes2966 So funny! 😂 Great video!

  • @markotrieste
    @markotrieste Місяць тому +1

    Hi, it's been four years now that I do low carb (zero sugar and refined grains, some leafy greens and the occasional whole grain biscuit with coffee) and intermittent fasting (+hiit and resistance training), lost weight improved health, however, my latest HOMA-IR is still slightly above the threshold of 2. U
    I wonder what is the problem. Shall I go even stricter on carbs? even fibre?

  • @roxannebrooksadamson3208
    @roxannebrooksadamson3208 Місяць тому

    Very good explanation. When I asked my gp why I could not get my blood sugar down below 130 I got crickets. On carnivore occasionally. My sugar would go to 70. But most of the day and night it was above 120-130. It was so frustrating. I am diet control only. So a short term of a glp agonist might Help increase insulin?

  • @DaveIrish66
    @DaveIrish66 Місяць тому

    I am seeing benefits from using ketone IQ. I run fasted and have had lows in the past . Very low carb diet here.👍

  • @ralfschwartz88
    @ralfschwartz88 Місяць тому +1

    This seems related to the phenomenon of upward drifting serum glucose and A1C in the long term carnivores (especially LMHRs). An effect of insulin suppression/lack of phase 1 response?

  • @TomSmith-cv8hk
    @TomSmith-cv8hk Місяць тому

    Currently doing a Doc Hudson, turning right to go left need a tighter LSD though.

  • @sunwm2003
    @sunwm2003 19 днів тому

    Dr, how do you reduce the risk of blood sugar goes too low if you raise the insulin intake and lower the carb intake at the same time?

  • @robertspinks835
    @robertspinks835 Місяць тому +1

    My fasting insulin stays at 6 no matter what I do
    Even experimenting with some metformin but that’s only improved the fasting glucose

  • @DavidC-rt3or
    @DavidC-rt3or Місяць тому

    I am curious though.. you mention you can produce large amounts of insulin to clear glucose.. if you were to eat something say of 90g carbs.. would it take you the "normal" 1 to 2hrs to come back to a normal glucose range?

  • @heatherburt2818
    @heatherburt2818 15 днів тому

    This is fascinating, but I have questions. I have T1D. I transitioned from low-carb to carnivore 3 weeks ago. My total daily insulin dose pre-carnivore was about 30 units (last A1C was 5.9). In the first few days of close to zero carb, my TDD dropped to 20 units, but it has since crept back up, despite the continued absence of carbs. Dr. Cywes is saying that in the treating of T1D and T2D with a keto/carnivore diet, insulin requirements generally increase before they can decrease. I'm not sure I understand the physiology of this phenomenon. Could someone explain?

  • @jmh8510
    @jmh8510 Місяць тому +3

    Huh, at 20:52??
    “Elevated a1c is a t2 problem not a t1 problem “
    My a1c was almost at 13 when I got dx in er/icu while in ketoacidosis. My bs was 980. My fasting bs a few months prior at annual physical was 76. Bonafide type 1.
    What is he saying with this? My a1c can stay at 6.4 and I don’t need to worry about it? I’m doing all I know to do, and would love to have a dr Bernstein a1c😢

    • @robertcywes2966
      @robertcywes2966 Місяць тому +1

      Yes. Of course at dx. But on insulin high A1c is insulin resistance or diabulemia

    • @robertcywes2966
      @robertcywes2966 Місяць тому +1

      Goal is A1c 5.2. V achievable

    • @jmh8510
      @jmh8510 Місяць тому

      @@robertcywes2966 what else can I do to get it down? With this disease I basically have a toddler with me 24/7.
      The past almost 20 yrs I’ve gone between 5.7 & 6.5. Was vegan for a while (BAD experience, but a1c was the 5.7). I eat super low carb, exercise, no smoking or alcohol. Nonstarchy Vegetables here and there. I do have small amount of fruit 2-3 x per week….but to cut out the only thing left I enjoy to get down a few points is just, well….🥺😩

  • @AltGenX
    @AltGenX Місяць тому +1

    💯

  • @anachung5223
    @anachung5223 Місяць тому

    Hi Dr C. My c-peptide and insulin are same as your numbers but my sugar is very high. I was diagnosed type 2. Been on ketovore for the past 5 years but my sugar hasnt budged. Im on metformin now but doesnt make any difference on my a1c or fasting sugar. Frustrating. Im going to talk to my dr and try your method. Thank you!

    • @DaveIrish66
      @DaveIrish66 Місяць тому

      Have you tried going zero carb for a period of time? Why are you on metformin? These meds tend to make you lose lean muscle mass, which will raise blood sugar from my understanding levels.

    • @anachung5223
      @anachung5223 Місяць тому +1

      I'm actually ketovore eating mostly carnivore. I asked for it bc of frustration. I've been on ketovore for about 5 years but my a1c hasn't dropped. Like I said my c-peptide and insulin numbers are as low as dr Cs. So I'm going to ask my dr to treat me w Dr Cs protocol. It also took me over a year to gain 10lbs. I also exercise 5 days a wk, w weight and cardio. I know this is TMI 😂

  • @tater9384
    @tater9384 Місяць тому +2

    In order to "go up to come down", won't using a large amount of insulin add a significant amount of body fat? Isn't that counter-productive? This is where I am stuck. [DM2 X 25 years, Insulin X 15 years, insulin pump X 10 years (~40 u/day), C Peptide 0.5, A1c 5.4-6.0.] Or does this only work on a Keto diet?

    • @robertcywes2966
      @robertcywes2966 Місяць тому

      May transiently gain a little wt

    • @robertcywes2966
      @robertcywes2966 Місяць тому

      Needs ultra low carb diet

    • @tater9384
      @tater9384 Місяць тому

      @@robertcywes2966 Thanks! Yeah - I am about halfway there. Dropping the remaining carbs, as you know, is difficult. My older sister (Type 2) is struggling with a Keto diet, but getting there. Also a recipient of two stents about 2 years ago, so my cardiologist isn't keen on Keto. 😉

  • @WickedLowCarb
    @WickedLowCarb Місяць тому +2

    I would very much appreciate an answer to this question, if there is one, or a video on it. I eat very low carb (less than 15 total grams per day, if that), take no meds and wear a CGM. My CGM indicates my 90-day glucose average as 96. During the day, it ranges from 95 to 105, occasionally a little higher or a little lower. This is corroborated by 2 different finger-stick glucose meters I have. So why do my 2 most recent hbA1C test results indicate 5.9 and 6.1? Over the last 2 years, my fasting insulin has ranged from 2 to 7 and my c-peptides have ranged from 1.1 to 1.7. I’ve read other people’s posts with this same issue, but never seen an answer.

    • @robertcywes2966
      @robertcywes2966 Місяць тому

      Watch my insulin suppression videos

    • @WickedLowCarb
      @WickedLowCarb Місяць тому

      @@robertcywes2966 Dr. Cywes, thank you for your reply. I have watched 3 of the videos but need to watch them again to truly understand all that you say. However, the one question that sticks in my mind that I can’t resolve is this: if my Dexcom G7 is measuring the amount of glycated blood and my hbA1c is measuring the amount of glycated blood, why aren’t they the same number? They aren’t even close. It just doesn’t make sense to me. Thank you again for responding and I really find your videos to be so informative!

    • @johnp7158
      @johnp7158 Місяць тому

      @@WickedLowCarb look up dry fasting club

    • @frederickhandani6419
      @frederickhandani6419 Місяць тому

      @@WickedLowCarb G7 can't measure true hba1c because it only scan the glucose at interstitial fluid and get that hba1c number from formulated calculation. True hba1c is collected from your bloodworks

  • @Cadets1986
    @Cadets1986 Місяць тому

    if our a1c is 5.1 but we're not losing weight can we still be insulin resistant? CPep is 2

  • @tracy3812
    @tracy3812 Місяць тому +4

    If insulin is an anabolic hormone-is there any link to tumor growth (malignant or benign)?

    • @robertcywes2966
      @robertcywes2966 Місяць тому +5

      Absolutely! Insulin resistance tightly associated w cancer

    • @tracy3812
      @tracy3812 Місяць тому

      @@robertcywes2966 Ty! I’ve been telling this to my onc but he says there’s no data/studies. BS.

  • @VolkyHaus
    @VolkyHaus Місяць тому

    Dr. is that young man taking only lantus?

  • @user-ho6wk7me3j
    @user-ho6wk7me3j Місяць тому

    Can I stop my insulin and do canavore safely

    • @carriesing
      @carriesing Місяць тому

      Monitor your glucose carefully. Taper so you don’t die!

  • @rsdaarud
    @rsdaarud 3 дні тому

    Give more to get less!

  • @DaveIrish66
    @DaveIrish66 Місяць тому

    Give your fruit to your endocrinologist. 🤣🤣🤣

  • @joecrone9862
    @joecrone9862 Місяць тому +1

    I was with ya till that nonsense about rugby being better than football?! Made doubt everything.

    • @robertcywes2966
      @robertcywes2966 Місяць тому +2

      Come on watch a game of Rugby go to the seventh tournament in LA and you will understand

    • @judywitthoft1122
      @judywitthoft1122 Місяць тому +1

      Yeah....rugby is the best, especially if you're South African😊😊😊