Autopsies were the source for the discovery of cholesterol in plaques. Atherosclerosis is a disease with a long research history. The role of cholesterol in atherosclerosis was initially reported in 1910 when it was discovered cholesterol content in atherosclerotic plaques of human diseased aorta was 25 times higher than that of normal aortas. There is an extensive history of additional discoveries including demonstrating that heart attacks were associated with increased blood cholesterol levels, especially LDL-C. In contrast, when blood high-density lipoprotein (HDL) levels rise, the heart attack risk is reduced. Moreover, the beneficial effects of HDL cholesterol (HDL-C) and the negative effects of LDL-C on heart diseases were further confirmed by the Framingham Heart Study (long-term, multigenerational study). That does not mean cholesterol is the sole cause of plaque, nor the only component. As stated in the video, plaques are comprised cholesterol, fatty substances, cellular waste products, calcium and fibrin. And atherosclerosis starts from injury to lining of the artery wall, as well as inflammation. Much more is understood about homeostasis between HDL and LDL levels. Additionally factors such as genetic inheritance and other environmental factors impact risk factors.
@@healthdecide But I can't find a paper/study of an autopsy showing/demonstrating that. Where they would dissect the artery of few dead persons, analyze what's inside and demonstrate that's it's indeed cholesterol. If it was done, it should be easy to find few. I keep searching but I can't find any. Would you have any to show me, please?
@Goodmorning1221- a simple google search pulls up many images of dissected arteries with atherosclerotic plaque from autopsies. You can also find images of plaques under a microscope that show components.
Plz make videos of respiratory system disorders
Thanks for your request, we don't have immediate plans for respiratory system disorder videos but will follow up if they get added!
@@healthdecide k thank you
@@Minitravler You're welcome. Please let us know if you have any other requests!
1:13 Please, show me the autopsies proving that the plaque is made from cholesterol.
Autopsies were the source for the discovery of cholesterol in plaques. Atherosclerosis is a disease with a long research history. The role of cholesterol in atherosclerosis was initially reported in 1910 when it was discovered cholesterol content in atherosclerotic plaques of human diseased aorta was 25 times higher than that of normal aortas. There is an extensive history of additional discoveries including demonstrating that heart attacks were associated with increased blood cholesterol levels, especially LDL-C. In contrast, when blood high-density lipoprotein (HDL) levels rise, the heart attack risk is reduced. Moreover, the beneficial effects of HDL cholesterol (HDL-C) and the negative effects of LDL-C on heart diseases were further confirmed by the Framingham Heart Study (long-term, multigenerational study).
That does not mean cholesterol is the sole cause of plaque, nor the only component. As stated in the video, plaques are comprised cholesterol, fatty substances, cellular waste products, calcium and fibrin. And atherosclerosis starts from injury to lining of the artery wall, as well as inflammation. Much more is understood about homeostasis between HDL and LDL levels. Additionally factors such as genetic inheritance and other environmental factors impact risk factors.
@@healthdecide But I can't find a paper/study of an autopsy showing/demonstrating that. Where they would dissect the artery of few dead persons, analyze what's inside and demonstrate that's it's indeed cholesterol.
If it was done, it should be easy to find few. I keep searching but I can't find any.
Would you have any to show me, please?
@Goodmorning1221- a simple google search pulls up many images of dissected arteries with atherosclerotic plaque from autopsies. You can also find images of plaques under a microscope that show components.
ua-cam.com/video/JwcZsiGztws/v-deo.htmlsi=l1A6S9zmhMpcDdXv
Treat your sicknesses and prevent from atherosclerosis :)
Dr John McDougall 😊