ONE Supplement SLASHES Risk of Death by Over 80%?
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- Опубліковано 1 кві 2024
- This supplement is doing it... again!
We already have seen 2023 study showing taurine increases longevity 10-12% in mice.
But, this is only half of the picture.
Today, we’ll explore another shocking study on longevity that examines how taurine affects the risk of lifetime death from a common chronic condition affecting one in six people.
In this study, they also compared Vitamin E and selenium to taurine. Who won, who lost, and by how much?
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Disclaimer & Disclosure: The information in this video and/or at this channel is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice. It is intended as a sharing of knowledge, educational and information from the research and experience of Rimon, who encourages you to make your own health care decisions based upon your research and in partnership with a qualified health care professional.
Rimon is not a medical doctor. If there is a contradiction between the advice here to your doctor or local authorities, always go with the doctor and the authorities.
Statements made, or solutions suggested in this video and/or at this channel are not intended to diagnose, treat, cure, or prevent any disease.
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Is it ok to mix NAC glycine and NMN TMG, is it ok to take both. My family memeber is sick and Im tryiing to help, please I hope you can answer.
I am 80. I use 3g daily. Improved sleeping. Besides I take liposomale nicotinamide riboside+TMG+ptorostilbene;complex Magnesium glycinate+threonate+citrate; omega3. Daily walking 3-6km, table tennis training 3 times 2 oures weekly
Sounds fantastic Tony 👍🏻
You're much more intelligent than men half your age!
Add glycine to your list. We don't get nearly enough from our diet and it's essential for our bodies to process collagen. I take about 4 tsp daily.
@@yogimaster1 Isn't that included in TMG, or is that not usable as glycine? (or not enough if taking 1-2 g TMG/day?)
that's a huge line of supplements just like your life span. You go Tony
my buddy In Arizona just passed away last October at age 47! He went into the hospital on Friday and was on life support by Saturday night! They kept him alive until Thursday when his sister could show up and then they pulled the plug! He was a single dad with a daughter named Valerie! Im still heart broken and having a hard time dealing with it. If you make it past 70 your doing good but its hard because the food industry is poisoning people like my buddy!!!!! :(
I’m sorry for your loss. What did he die from? Was it cardiac problems or a freak illness?
@@vicki4552 thank you .... some form of lung cancer. I dont remember what his sister told me and she ghosted me after a few calls. I was way too upset to remember and it still bothers me today. Just shouldn't have happened! :(
Thanks for telling us about the One Supplement at the start of the Video.
a shortcut!
I watched a video about taurine about a half year ago and decided to try it. Even with other vitamins, my main problem was a few years of tiredness and a complete lack of interest in doing anything. It took about a week and a half for me to realize the change. I woke up that morning and actually started working on one of my hobbies. It took me a few weeks to realize that my mental outlook changed in a subtile but important way. I'm still taking it and almost always continue to have an improved mental outlook. I don't care about length of life, only quality of life. I'm confident this supplement is helping me, but I honestly can't say if it can help anyone else. (I'm 66 yro)
How much do you take
@@KelvindeWolfe I bought bulk generic capsules. They are 2000mg. For the first week and a half I took one a day. After I realized it was helping me, I decided to take one in the morning and one in the evening. The bottle recommends 4 a day.
I had a similar problem except I lost two fingers in a firecracker accident when I was ten. But since I’ve been taking taurine I grew back my fingers, plus two more! It may not work for everyone but it definitely works for me.
I don’t necessarily want to live as long as possible. I want to live as healthy as possible. What good is it to live as long as possible if one is going to be miserable for the last 30 years of their life? ….. I take Taurine because it helps me sleep.
Well Taurine has more effect on healthspan than on lifespan. That's why the mice doesn’t die so young.
So, taurine is exactly what you want then!
When you are bed ridden in the last years of life, why even exist? Health is wealth!
@@marnold2791 Because one day that won't have to happen.
If I was old now I would want to try hang on for the next 10 years, World is about to change faster than ever, A lot of health issues are going to be resolved within the next 10-20 years.
Yeah, live to be 130 but be connected to all sorts of tubes, jacked up on all sorts of chemicals to prop me up, and bionics to physically function. Nah, I'd rather burn out than fade away.
@@ShaneMcGrath.yep. Don’t die. Help is on the way. Unless we destroy ourselves.
I listened the whole video because you did not click bait us
Ive been taking taurine daily for almost 8 years and it really helps with my energy levels and also helps with water bloat you can get in a bulking phase. It makes you look leaner and more defined. Also if you live in an area with a lot of air pollution it can help mitigate the damage done to the lungs and brain. Taurine also helps with anything lung related, for example being an ex smoker and trying to restore lung function quicker this is partly because it is the main amino acid in lung tissue.
Why would it make you leaner or more defined?
@@ash9x9 Taurine is a regulator of fluid and electrolyte balance and helps reduce water retention. This means more water where we want it, in the muscles and body cells and less in the interstitial spaces, aka body fat. An extreme level of this bloating would be something like moon face which is normally caused by binge eating too much especially carbs and salt and not getting in enough potassium to balance it out, also too much aldosterone which is the body’s way of holding onto salt for whatever reason will have the same bloating effect. Taurine will help reduce this bloated look.
Taurine also helps with burning fat during exercise, lowering body fat and potentially sparring some muscle glycogen, both mechanisms contributing to a leaner more muscular look.
Creatine also goes very well together with Taurine, and will help stop the cramps some people get with creatine use. Which again is down to the electrolyte balancing properties it has.
My main reason for taking taurine is because it helps me with my endurance power, like HIIT, cycling and things like hill sprints. I always speculated it’s because the muscles are better hydrated and saturated with electrolytes. Anything from 1g + will have a positive effect.
I started taking Taurine a few months ago and my liver scores got about 10% better.
hmm i quit smoking a year ago and hopefully this will help me. will try it out. thanks for the specific info
I have a lung nodule already 9mm ,i just started taurine ,hope it can help ,thank you.
Taurine has elevated my metabolism, boosted energy levels, helped IBS/digestion significantly.
Can u elaborate on it helping ur ibs
@@ketokarbs3671 i also would like to know about it
What is the best bio available form of taurine and which supplement is recommended?
Yeah, please elaborate on the IBS/digestive problems. I've been dealing with IBS and digestive issues for years now. In what way taurine helped you?
Been taking taurine for about 3 months at 1000 mg. Daily in the morning. There is a big improvement in the calmness of my mind. Went from 4 to 5 hrs of sleep a night to 6 to 8 hrs. I also started using green sound while i sleep for i have tinnitus for 12 years. This supplement helped me loads with diabetes. Im having gastric sleeve the 29th of april. And by going on taurine i was able to finish my insulin reduction from 10 units 2 x daily to no insulin at all. Im On the 2 week liver reduction fast before surgery and the pharmacist and hospitalist want me to continue taurine until 2 days before surgery. This is one supplement i have intention to continue with my beariatric vitamins ill have to take rest of my life. Im 67 years old and never used vitamin supplements. Until year and half ago.
Thanks for your research, I’ve been taking Taurine for about 2 decades now thanks to my Naturopath Doctor.
Do you notice anything worth sharing after 2 decades?
@@mark2073 He just died ? lol
Anyone with a heart arrhythmia should absolutely try 1000mg 2 times daily without food. My mom and I both have it. My mom has had a debilitating arrhythmia for 30 years and read about taurine lessening or altogether stopping it. She was told she would have to live in a constant state of heart arrhythmias and that many people can live that way. She started taking taurine 5 years ago after being on many different heart meds for YEARS. She has had 2 small and very brief episodes since. I have not had any since I've been on it.
Try it, nothing to lose and everything to gain.
magnesium
2:14 hilarious editing. Thanks again for another quality video. I would double subscribe.
Very well explained. Thanks ❤
Well, here at just shy of 70 I don't have any medical maladies, eat moderately and healthily and I take only two supplements. One is 2x1000mg capsules of taurine and second is 2x300mg capsules each containing 250mg's of nicotinamide riboside and 50mg of pterostilbene. Some here may recognize the latter as being part of a product called "Basis" proffered by a company named Elysium. I take it (Basis) to foster mitochondrial health. Daily, first thing in the morning, I've been taking both with "Basis" having been taken for close to 10 years, and Taurine being taken for the last 2 years.
Some may ask how I feel, etc. Well, I feel fine. I haven't noticed anything too overt in turns of positive impacts. Certainly, there have been zero negatives. But maybe that's the point? My body just keeps ticking along. I have noticed, by way of comparison, that I seem to have more "pep" than my peers, colleagues and friends in the same age cohort. I can just keep going all day and have no problems with sleep. So perhaps the regime I mentioned (above) IS working, and properly? I'm certainly not expecting to feel and look like I was 20 again. But the energy is there whenever I need it.
But all that said let me also disclose this. Yes, I'm almost 70. Both my parents, now north of 90, are alive and while one (mom) is fading the other (father) is still motoring along and is viewed as something of a freak by his doctors. He has no maladies and takes no medications. Neither of them take supplements, at all - except possibly a 1-A-Day vitamin. So despite what I do the results might be more associated with good coding, meaning genetics, than any advantage rendered by the supplements. But since they're not hurting, I'll just keep doing what I'm doing and consider it all good.
Just some thoughts. Sorry for the long-winded write-up.
John~
My 2 cents: keep your father out of the medical industry to keep him safe. 🤞🏻👍🏻❤️
@@melaniejo5296 LOL! Thanks for the chuckle. You should picture him running down the street with the medical community trying to follow along with their charts, graphs, stethoscopes and blood test units trying to figure out why he's as healthy as he is. In fact he's a runner. Been one as far back as I can remember. Runs 3 times a week and each time runs about 20 miles. Yeah...did I mention he's a freak?
Trouble is, the doctors in trying to track him can't keep up. 🤣🤣 It's a wonder, I suppose, when you find yourself outliving your doctors. Or maybe that's poetry? I dunno. He doesn't mind them much. Did I mention he's ex-military? Yeah, that too. So you can probably picture the attitude. It's kind'a sort's the same one I have, too. So it goes.
John~
Great genes. Congrats.
I think you came from good stock! 5 stars for your parents and you!
Thank you! I enjoyed your info. I'm 60, with quite a few health problems. Trying to get healthy and love myself!
Another great and informative video! Taurine is very exciting and I look forward to more research being done, especially human trials, in the future. Early returns look good but the longevity field is littered with substances that looked good and then didn't pan out. But right now taking taurine may be a decent gamble. I've been taking 6g/day, an at one time, for a few months now. Hopefully it will pay off in the long run!
For anyone skeptical of taurine effectiveness, keep in mind that it is a standard nutrient added to breast milk replacement formulas. Scientists aren't entirely sure all the reasons it's so important for human health and development, but that it's important is beyond doubt.
Do they put growth hormone in breast milk replacements?
Yes, and I'm adding "I don't feel anything" parameter isn't relevant for aging (nor for cardiovascular disease...we don't feel plaque accumulation, for example). The aging process is feeling-less.
Wow. They add taurine to breast milk? Well then, just take taurine and we will break maximal lifespan. You have the proof; BREAST MILK!!!!????😂
is it possible to reverse "calcium buildup in arteries that was called age appropriate?" I was told my buildup was just that and when I expressed concern about this my cardiac doctor at the Cleveland Clinic told me she does not really feel that this is any indication of coronary heart disease nor should I be concerned, as it is just the way you age.
I then asked her for a calcium score blood test but she does not do that normally in her treatment and told me very bluntly that my exam was normal period.
I had to disagree. I do not want this buildup even if it was not excessive and was "normal" for my age. Can anyone here comment on their experience with this particular type of coronary artery buildup and if they were able to either stop it or reverse it? I know that taking Vit K2 in form of mk7 is what to do. But how much is recommended and how can I take an aggressive response to reversing this even though she told me 90% of all men develop this.. I would think that you cannot let this happen if you want to extend your life for as long as humanly possible. I need professional guidance imo.
My aunt is 103 years old. She is wheelchair bound but takes care of herself. I also want to live that long but do not want to be able to walk and take care of myself. I can see now how your joints begin to deteriorate. Hearing goes bad. Fingers get crooked. Mental accuity deteriorates. What can I do to give myself it's best chance to stop the progression of age related deterioration? Anyone? Please comment my best effort or who I can contact for advanced living goals?
@@gizmobentlyI assume you meant you do not want to NOT be able to walk ?? K2 mk7 yes but add vit D3 5-10k iu/daily as even if you get plenty of sunlight, given you are older you will synthesise it less so you need to supplement. Get your levels checked of vitD so you can feel how much you need to supplement but, it still might not alter your levels that much. A few doctors will suggest the dosage I mentioned. UA-cam has plenty of great specialists who do seminars or videos to help you know what I mentioned is accurate and it’s great to be learning from these highly experienced professionals.
Thank you for sharing this. I will continue to investigate this.
Hi check the previous investigation:
ua-cam.com/video/U6mh0_yTBnY/v-deo.html
I take 1 g as often as I feel up to 4-6 times a day, best time is before sleep.
Great exposition. Thanks!
Very interesting video!
Good info
Great, thank you for the video:) Can you provide a good dose recommendation? And how often ?
Hi Jennifer, I will delve deeper in the next video with another amazing study on doses!
I'm currently experimenting with 4-5 grams per day, I take before my afternoon nap, or if I wake up in the middle of the night - it helps me calm my mind. In the morning - it's making me sluggish.
Please Subscribe 😉
Very good video :)
Thank you John you're very kind... now subscribe 😊
I have an "antioxidant budget" because so many supplements are also pro-antioxidants. I usually limit my AO's to grape seed, green tea (catechins) and alpha-lipoic acid. Sometimes NAC in-between work out days. I want to take quecetin and curcumin at some point again and astaxantin on sunny days out in the summer.
Why astaxanthin in sun?
Its amazing that these things have been known since 2002-4 with negligible adobtion in society.
No money = no payments for marketing people. The 2023 study really forced me to revisited all these pervious studies.
Follow the money!
Doctors are just pseudo pharmaceutical reps!
The truth is that all of these supplements work together as a whole, and to benefit from them you get it from your food. If our food was totally nutrient dense, health issues and chronic illness would be a thing of the past. The people who knows this, but keep pushing the agenda will answer to their own enemy inside. We, the people are lost, and is willing to accept anything that is giving to us, and the scientific world understands this, but continues to prey upon those with no knowledge, but I can say this with conviction that no stone will be left unturned as Mother Nature is an excellent judge of character. The INTERNET has provided us with a wealth of knowledge, but you have to learn how to do your own deciphering of information, and use it intelligently and share❤
If food had less sugar in it, diabetes might not be so prevalent. Processed food is very dangerous.
@@michelelindseth8250most foods might as well be cardboard nutrionally compared to 60+ years ago.
Most people have food addiction which leads to less taurine , so supplements like taurine are needed for health
Fascinating!!!
Now thaf you explain the concept of some antioxidants interfering with the body at an early age, it is understandable.!
69M, been using E and Se for year's.
Thank you!
Subscribed.
Great video
Had my TAURINE this morning😊
I've studied/Used this for years....
Well said.
Death & Old Age Sufferings: Cancer, Disease, Organ Failure ( kidney ....), HBP, Diabetes, Inflammations leads to painful skin diseases (Acne), Quality Sleep, Teeth Plaque & loss making eating difficult, Visual problems, Financial Security, Frailty of the bones of the body, Facial Sagging & decline in beauty.........
and?
@@janebond8342😂😂
Thoughts on some research showing long term taurine use can downregulate your neurons receptor sensitivity to Gaba? I paused my taurine use because of this, I think for now more research is needed. My concern is over the long term it could act like long term anti-depressant usage where some users unfortunately develop dependance on anti-depressants as long term anti depressant usage can gradually down regulate neuronal synaptic serotonin sensitivity in some individuals.
Soo eat food rather! 🎉
It can be. Extensive research is needed.
But certainly majority of people does not experience adverse neurological effects from taking doses up to 3 grams per day.
Been on and off the supplement for a year. No dependency at all.
Try to mix it with food or coffee. Latter one causes arrhythmia.
Yes, It activates the GABAA and glycine receptors. I will make a video on it later this year. It's the main concern, but it seems after a while the receptor resists taurine and you get no effect in continuous supplementation. The lifespan animals didn't show any negative impact, but it's an important side effect to track.
Taking with food also can reduce this effect.
Hey Rimon, I'm 33 and taking codliver oil for quite a time now. Unfortunately it has additional Vitamin E with about 6mg in 10ml. Should I consider taking other supplements for gaining DHA and EPA or do you think this isn't a problem according to the fairly low dose of 50% RDA?
Hi I wouldn't worry about it. It's minimal to protect the oxidation of the fish oil. Fish oil consumes (and balances) this content in your body too... its good.
Extremely beneficial video, thank you. Been taking about 6-8g of taurine per day, feel so much better, especially my sleep quality and skin. Thanks Rimon
so u take all at once or divided doses
@@wasimahmed1570 divided dose. During Ramadhan I was taking 4g after Iftar and another 4g at suhoor time (just before fajr). Hope this helps.
@@TheReminderChannnel Jazak ALLAH FOR LETTING ME know ....EID MUBARAK to u and all
@@wasimahmed1570 BarakAllahufeek my dear brother, Eid Mubarak
Why that amount?
No, risk of death is 100%, always was and always will be.
LUV!!
I started taking this and I have been alive since I started taking it so I am a living example of what you say that it’s an insurance against mortality. But I also eat good sometimes and drink water every once and awhile. I also sleep once a week so it’s really hard to say and that’s why I think the best thing you can do is combine taurine into a more extensive protocol just to be sure.
We see dramatic life extension in short lived species (mice, rats) with interventions, but not so much in long lived species (e.g., monkeys humans). So if there is any carry over life extension effect at at all from mice to humans with an intervention,, we will likely see 5X less impact in humans. So if you see a 10% effect in mice, you might see a 2% or less effect in humans.
Most of the claims in this video are in conclusive and not supported by the real research going on in many Medical Univerisities.
Hi just a comment on how to interpret survival functions. You say that the mouse survival curve with vit E catches up with Taurine around 23 months, and do not recommend taking vit E for humans under 70. However, this is a misinterpretation of the survival curve. The risk of death at a certain age is the SLOPE of the survival curve (usually called the hazard rate/probability). This becomes less than the for the Taurine survival curve around 15 months: that means the probability of death for mice taking vit E who are 15 months or older is less than for those taking Taurine. The main benefits of Taurine are enjoyed by the younger mice (up to 15 months). Hence it is best to supplement with Taurine when young (mice below 15 months) and vit E when old (above 12 months). This is clearer if you plot the hazard rate rather than the survival rate, and indeed if you plotted the hazard ratio (vit E versus Taurine). I am 65, so I guess I should start vit E now!
I had not noticed it, but you are right. Actually the gap starts to close from the 9-th month. It would be very interesting to do a trial with taurine and replace it or add with vit E after the 9-th month.
An interesting observation! Maybe the researchers should have presented a survival function graph as well.
Maybe the next time!
This must mean that we should look for things giving another curve than we get for taurine on mice.
Ideal would be if it started further out, and then contonued with less slope than the control group.
A slope like the end of the vitamin E group!
But it's not just the slope of the curve for one group by itself that's interesting. Shouldn't it be a comparison between the slopes of the groups at the same age? I have to re-watch the video to look for that. It's a little complicated to eyeball that, though!
I've been taking Taurine 5 grams a day since 1825 BC, I'll say it makes you live longer, much much longer. The bad thing is I can't convince anyone, too many non believers. I have a tough time at the DMV when they want to see my birth certificate to confirm my age, my birth certificate is in Cuneiform, they told me they can't find anyone to read it, so I'm driving on a temp license.
How did you get this supplement back in the day? :) Me too around 300 years old, don't tell anybody!
Hi, reviewing I found out that R-ALA and Omega 3 supplements that I take have Vitamin E and Selenium. Seems to be low dose, less than 10mg. I am 27, so I believe I should change the brand and look for one without E and selenium right?
I would avoid Vitamin E... selenium isn't an issue, it's neutral.
I have been taking 7 g of taurine in my daily lunch smoothie, and now believe this is why I feel sleepy for several hours afterwards. Thanks to other commenters who noted this effect. I will now start taking it before going to sleep at night! I look forward to better sleep and better energy throughout the day.
Rimon, I love your channel and donated to your wife's fund. I have a suggestion for you to consider.
@rimon I learned about taurine from you and followed your recommended dosage for someone my age. I believe this is a great supplement and encourage everyone over 65 to take it. I am so glad I just learned from today's broadcast to take taurine at night and not midday. I strongly encourage you to alert your followers that it can make one very sleepy, especially at 7 grams a day. Many will not realize why their energy has declined and will stop exercising, going out with friends, and taking care of everything needed for a healthy independent life. This is a catch-22, for if this goes on for very long, they will actually become frail and not be able to reverse course.
Why so much ?? Isn’t 1-2g the recommended dose ??
Is 7 grams okay? Isnt it to much?
@@willcook403 @ainhaga Rimon recommends 7 grams someone in their seventies.
The same thing happened to me!. It actually made me feel quite sleepy, was just informed it was better to take in the evening.
I just noticed that taurine reduces my pulse
Just don't let it get down to zero. That could be a problem.
@@lashedbutnotleashed1984 🤣
@@lashedbutnotleashed1984
They did a study a while back, and they found out that a pulse getting close to zero was not indicative of good health...They asserted that more research was needed in order to formulate a more definitive conclusion.
@@deavman Well, a pulse getting close to zero is generally not the problem, and I never said it was. It is when it gets to zero and stays there that the problems tend to arise.
There's a lot of debate over whether it is the omega 3 in fish - or something else about fish - that reduces mortality. I wonder could most of it be the taurine in fish? Other food sources of taurine - like meat and dairy - could have more detrimental effects that offset its positive ones? Just a theory, but I do wonder.
Probably both! Remember taurine in seafood is in the 50-200mg per day...in the studies they showed efficacy in 4-8 grams and more. So you only begin to get the longevity benefits..
While I do believe there's something more than the omega 3 in fish for mortality/longevity, I now avoid regular consumption of seafood because of microplastics, heavy metals, parasites and other toxins. I miss eating it, but don't feel it's something to eat more than 1-2x a week at most.
Have you checked out what light does? See an old film of Dr Ott
What type of vitamin E are you suggesting a person should supplement with?
I would suggest Tocotrienol.
What is a good amount to take daily?
How much taurine per body weight should be used that would be effective without using extreme dosing? Thanks, great video, well narrated and explained without getting long winded. Thanks again.
Hi I will delve deeper into future videos. For now I I think 5-8 grams... usually 1 gram per decade of life. I'm still reading more and more studies to be certain. This seems the right range
Isn't it odd that the study didn't include a second control group without diabetes? After all, it could be that taurine (in large doses) doesn't help or even harms people who don't have T2D. I think we must be careful about extrapolating too much from this one study.
I fall for all of these supplement videos and find no change. Been on Taurine for months along with a bunch of other supplements and no difference in how I feel or look. Just a wee bit poorer
What did you take else?
What did you take else?
What do you want to feel lady? It’s doing its thing behind the scenes on a molecular level, you’re expecting it to make you Supergirl? 🤣
Supplements definitely have their place but this obsession with them as some kind of wonder method for whole body rejuvenation is ridiculous. A healthy organic diet, proper breathing, fresh air, pure water, whole body joint mobility exercise can do much much more. As for me personally I take an ounce of Wujinsan Fulvic Acid daily, follow the Medical Medium protocols, do endogenous respiration with the Frolov Respiratory Trainer, and full body Joint Mobility exercise with Scott Sonnon's Intu-Flow Joint Mobility program. Eat plenty of steamed potatoes, asparagus, zucchini, etc.
Think of it like its maintaining the body, it’s not gunna be like meth and give you crazy energy haha
Question for Rimon: Eight known substances are classified as "Vitamin E" (the four Tocopherols, and the four Tocotrienols). All eight, when taken together, are referred to as "Natural vitamin E". Rarely do studies use this Natural Vitamin E. The studies usually opt for the cheapest synthetic Vitamin E (DL-Alpha-Tocopherol). So, what Vitamin E substance (or substances) were used in this study?
Alpha-tocopherol. They didn't specify DL or d-alpha-tocopherol. I find it difficult to believe a research lab will be skimpy and use the cheaper synthetic version
Good explanation.
Your conclusions about the effects of Vitamin E in this study may be missing a key point about the type of Vitamin E used. Nothing beyond the abstract of the cited study is available for free; but it is very common for such studies to use one of the cheapest form of Vitamin E available: racemic alpha tocopherol.
Aside from the fact that the alpha isomer is not the most common form of tocopherol found in natural foods, the racemic form of it (d,l-alpha-tocopherol) is COMPLETELY unnatural. As such, its effects on the bodies of rats (and humans) may be slightly harmful. It is not unreasonable to speculate that using a form of Vitamin E that IS found in nature (d-alpha-tocopherol) might be more supportive of health, both in the short AND long term.
thank you
Yes I had to buy this study... many studies I show in my channel I pay for. They used d-alpha...the highlight of the study is taurine, anyhow
@@WellnessMessiah Taurine may have been the "highlight" of the study, but they also spent time, effort and money on a separate Vitamin E and selenium group, and consequently you took several minutes to discuss Vitamin E, as well. Which is why I'm responding to your video. If you only wanted viewers to engage with you about the taurine, you should have made that clear. If the researchers only wanted to study taurine, they shouldn't have wasted time and money on Vitamin E and selenium.
As to "They used d-alpha...", I assume you're referring to the single mouse study on which your presentation focused. But you didn't merely present the single mouse study; you offered ancillary evidence in the form of a meta-analysis from 2012 involving antioxidants that (supposedly) demonstrated a) no benefit and b) potential harm from Vitamin E supplementation. Unfortunately, the stated selection criteria for included studies is no more specific than "Vitamin E".
But I'd bet good money that most (if not all) of those studies used the cheaper, artificial racemic mixture, because over the past two-plus decades I've been scouring the available literature, I'm pretty sure I've read many of those included studies. But setting that aside, unless YOU'VE read every one of the individual studies in that meta-analysis, and seen that most or all use the non-racemic d-alpha tocopherol (vs the racemic d,l-alpha tocopherol), whatever time you spent discussing it in your presentation is not enough to do it justice. The issue of racemic toxicity is important, whether you understand it or not.
And as far as the single taurine-Vitamin-E-selenium study: the presence (or absence) of an "l" (d,l-alpha tocopherol vs d-alpha tocopherol) is easy to overlook, especially if you're unaccustomed to the distinction. Not seeing a copy-pasted quote or (better yet) the passage in the Materials and Methods section myself. I will default to my decades-long experience reading such studies. the vast majority of which even now use the cheaper, unnatural racemic mixture.
And that doesn't even address the fact that the d-alpha tocopherol isomer is never found in isolation in nature; it is one of eight naturally-occurring isomers, the most prevalent of which by far is the d-GAMMA-tocopherol form. But honoring that fact would make such studies even MORE expensive, and funding for non-patent-able supplements is hard enough to come by.
Believe me, I WISH biochemistry was simpler. But I value understanding over simplicity when it comes to health. I hope you do, too.
Does it make a difference which vitamin E they were using in the trial? Was it vitamin E tocopherol OR Vitamin E tocotrienols they were using?
Many are deficient in Vit D. Which is also a hormone, affects 200 genes to improve many factors related to a 25% reduction in mortality and contributes to robust health. Combined with its necessary cofactors k2, Magnesium, Zinc, Boron (slowing D metabolism) and exercise. Has numerous layers of protection/improving: autoimmune disorders/immune system defenses, is anti-inflammatory (CV/diabetes), mental status/wellbeing, hormone production, sleep, recovery, anticancer effects etc.
Missing Vit D status in those studies is a serious flaw in the multivariate analysis, as Vit D another fat soluble Vitamin besides Vit E imparts significant benefits. Also Tocotrienols vs Tocopherols both making up the Vit D classification, already show Tocotrienols at various doses are superior and beneficial over Tocopherols.
What do you think of a low dose of supplemental vitamin A to just reach the RDA though? I mean it's quite difficult to reach that level with your diet alone when you don't want to harm animals or eat lots of spinach or certain fruits each day. Is artificial/isolated vitamine A worse than a deficiency? Should I also avoid too much vitamine E and A from natural sources?
Hi Vitamin E is straightforward no for young people. Vitamin A can help in certain conditions... better to get in food anyhow (organ meat, grass fed liver), not a supplement
Wouldn't it be interesting to try optimal supplementation research on mice?
Research with single substances might not be ideal, since most of these work together. Giving just one thing might even be detrimental!
We might get some kind of answer to the question if we need more than the RDA, or not.
I would like to know if Bruce Ames triage theory is valid for m9re than a few vitamins, minerals, and non proteine amino acids like taurine.
Taurine is synthesized from methionine and cysteine in the body. If you eat red meat you're getting plenty of methionine, if not too much, and I already supplement cysteine in the form of NAC. But is it enough?
I take taurine but I was diagnosed with prediabetes last year
prediabetes is reversible..
@@ash9x9 Ye but shouldn’t taurine have kept it from being a thing? I’m underweight and only eat whole foods. I have a host of food intolerances so my diet was already restrictive
@@SargeMaximuscan you eat meat and eggs ???
@@willcook403 I eat meat and eggs everyday
You can’t supplement your way out of a bad diet & lack of exercise.
Been on taurine its great
“Reduce your chances of death by 100%” that phrase is certainly impossible and a mistake.
Is there a particular Taurine you recommend?
There is no special formula, it's cheap material. Just buy from reputable brand with minimal fillers.
Subscribed again
Still don't get emails
The 1st 2 weeks it helped me feel more relaxed. So, it does have positive effects. Though, after 2 weeks, and after taking everyday for 1 year, I don't really notice any impact. Maybe it's still doing something for me but I can't tell??? Hopefully protective effects
Consider cycle one day a week off
I bough amino acid (glycine )powder is it the same as taurine or are they different.and can I take both if they are different?? Thanx lot
you must be a genius to ask a question like this.
Vitamin E consists of 8 different kinds. But supplements stubbornly give only alpha-tocoferol!
It's well known that this form disturbs the effect of the other forms. That's one probable reason why high doses of alpha-tocoferol isn't good for us.
The overuse of alpha-tocoferol in multivitamins and everywhere else as antioxidant is a problem!
By the way, the relation between vitamin E and vitamin C is that when vitamin E in our cell membranes is oxidized to protect the fat, it's restored by vitamin C. So, these two v8tamins work together to prevent the oxidation of the cell membranes.
With only vitamin E it would be a cascading effect of oxidation.
I guess researchers should give us, or the mice, every other form of vitamin E than alpha-tocoferol, and make sure we get enough of vitamin C to go along with that. (By enough, I mean someting in the order of 400 - 500 mg, and not the excessive doses some people belive we need.)
Exactly. I've made these two points over and over again on various venues....to deafening response. None of these reserachers ever talk about either the need to use Vit C with Vit E (otherwise the latter turns into a pro-oxidant)...or the need to use a full-spectrum Vit. E supplement in their research studies (otherwise, as you point out, the alpha 'crowds out' the other forms). Sometimes it feels like I've landed on Planet Stupid.
any tips for Parkinson's disease
So exactly which form of Vit E was used? If it was tocopherols, that is a bad form. Best form is tocotrienols. Please comment
Dose taurine magnesium has the same effect?
I take the tocotrienol form of Vitamin E , as well as vitamin A every other day, may need to think about discontinuing them. The reason I take them is because I know my diet doesn't contain enough vegetables.
I have the same concern. I’ve reduced my E and A supplements to every third day. I may eliminate them altogether. I take 200 iu of Selenium every other day. I’m trying to reduce my risk of prostate cancer recurrence post radical prostatectomy. I do a 16 hr fast everyday as the norm, and a 24 hr fast one day a week.
2 ounces of sunflower seeds will give you about 100% rda of vitamin E. Throw in 2 ounces of hazelnuts and a half of avocado daily and you're up to 200%. Likewise, vitamin A is pretty easy to get through food.
@@generalnguyenngocloan1700 I would maintain the Selenium daily, increase Vitamin D3 + k2 daily intake to 20,000 IU or higher and also look into mega dosing with nightly melatonin (has anti cancer) benefits.
The third point is quality of life. this is a huge omission!
Yes, you're correct - healthspan. My goal is define "lifespan" only, then you have healthpan and lifespan. Taurine helps in both but needs time!
Yes; quality of life is also known as "healthspan" (as opposed to lifespan) and GlyNac taken with Taurine has been studied as well. Together they attenuate the individual efficacy.
Am I to understand that you can mix Taurine in smoothies as well
Yes, because it seems to work on empty stomach and with food. Either way
Is it ok to mix NAC glycine and NMN TMG, is it ok to take both. My family memeber is sick and Im tryiing to help, please I hope you can answer.
right now I am taking NAC glycine niacin and magnesium all together don't know if that helps but I will pray for you and your family
@@carolmaplesden916 what a kind angel you are. God bless you and thank you
I take both and am 70. My health has improved immensely and all maladies have disappeared.
Taurine is good. Helped diminish arhythmia/tachycardia but the root cause was carbs, especially bread. The blood glucose spikes inflame your cardion vascular systems heart and veins. Gotta keep that low and you're ok
What type of Vitamin E did they use? Synthetic or Natural?
Did they use synthetic vitamin e in the study? There has been research showing that synthetic vitamin e is very bad for you.
What is the one supplement as a result?
I wish you would clarify the form of vitamin E. As the older traditional form of vitamin E tocopherol versus the newer form and promoted as being far more effective and beneficial is tocotrienol
Alpha-tocopherol. They didn't specify DL or d-alpha-tocopherol. I find it difficult to believe a research lab will be skimpy and use the cheaper synthetic version
@@WellnessMessiah better had they used a more balanced form with d-beta, d-delta and d-gamma tocopherol, not to mention the tocotrienols. It's not hard for me to believe that they would use a cheaper synthetic version.
News flash. We are all going to die.
Would you consider astaxanthin as an external antioxidant that would blunt the impact of exercise?
yes since it's fat soluble. It has little data on longevity, unlike vitamin E, beta carotene, and vitamin A. I suspect the same negative effect, and positive as we get old.
@@WellnessMessiah good thing I am getting old then
@@joebartles3986 I think astaxanthin for about 2 years now. I am 36, shredded and natural bodybuilder. It hasn't had any negative effect.
@@WellnessMessiah Is it therefore reasonable to conclude that all external antioxidants should only be taken from the age of 71?
@@say6837 great point!
What food has taurine
Today is day 70 of taurine supplementation. So 10 weeks. And 15 1/2 weeks of GlyNAC supplementation
I am 63 should i takeTaurine with a 3.4
aortic aneurysm ?
Today is for me day 32 of Taurine supplementation. Tomorrow is day 70 or 10 weeks of GlyNAC supplementation. In 2 months I will be 71 years old.
How many grams of taurine per day do you consume? I’m not sure what the minimum should be.
Taurine and NAC (a form of cysteine) are both sulfur containing amino acids along with methionine. There are also a lot of other supplements and foods high in sulfur compound, e.g. MSM, glucosamine, chondroitin, eggs, garlic, onions, et cetera. I would hazard a guess that there are diminishing returns and eventually negative effects of overdoing sulfur. For one, it increases acidity in the blood. While most of the PH diet and the like are taken out of context, if your body has to do too much PH buffering that is going to become a negative effect at some point. I personally do take taurine semi often, but not everyday and I tend to stagger it between NAC and eggs and the like. I think it helps to understand what first order effects the supplements and food you eat have and use them accordingly. I.e. taurine tends to increase exercise endurance when taken an hour or so before exercise, so on hard workout days I'll take some taurine. The next day while I'm recovering from the hard workout I assume I've increased my endogenous antioxidant needs and therefore take NAC to help increase glutathione production. I might also have eggs that day for the high amount of protein, fats, et cetera in order to help muscle recovery too..... hopefully these thoughts help!
Do you have any data to share, comparing your organ functionality and metabolic health indicators since beginning supplement use?
Any true, measurable evidence you're getting benefit? Even a perceived reduction in pain, increased energy, range of motion, etc.? Stay well.
@@generalnguyenngocloan1700 I take 2 grams in the morning and 2 grams in the evening. 4 grams per day was the minimum given per day in the study. 4 - 10 grams over all if my memory serves me correct. The exact amount that should be taken is unknown. Sorry, I didn't keep the source of the video I seen.
@@donaldzielke4124 My last health check was September 2022. I'm about to go in for another check. I was waiting for 16 weeks to go by (I'm on week 10) with the GlyNAC supplementation as that was the test time in human trials for the 74 year olds. GlyNAC supplementation restored the glutathione (the body's master antioxidant) levels in 74 year olds to levels similar to 24 year olds with 16 weeks of GlyNAC supplementation. According to mouse studies taurine supplementation added 10 to 12% increase in lifespan with the mice. GlyNAC added a 24% increase in lifespan. I'm doing both. I'm also doing resistance training 4 days a week with consumption of 150 - 180 grams of protein per day with certain amino acid supplementation (L-carnitine, L- leucine and creatine).I'm trying to reverse early onset sarcopenia. I'm seeing gains in the weights I lift as well as seeing muscle growth in my arms, shoulders, back and chest
Since September 2020 my weight has gone from 295 pounds (134 kilos) to 215 pounds (97 kilos). I did a number of water fasts with the unfortunate result of a lot of muscle loss. Hence the gym and the protein. I got another 30 pounds of fat loss to get to where I want to be, 185 lbs. I am photographing everything and keeping records of my blood pressure and glucose levels which are excellent. I do keto and now mostly carnivore with intermittent fasting.
I take 2 grams of NAC (N-acetal cystine) along with 2 grams of glycine. I do this amount twice a day. I buy kilo bags of Bulk Supplements off of Amazon. I also take 30 grams of Porcine collagen daily. And at least 15 grams of glycine in addition to what I get from the collagen (33%) and the GlyNAC. So about 25-30 grams per day of glycine.
This is a very important study, if you happen to be a diabetic rat. Does taurine affect humans not suffering from diabetes and if it does what are those affects ?
What about taking hydrogen water as an antioxidant if you're younger? Is that okay?
Hydrogen peroxide is corrosive water ,we uses externally for killing bacteria in infected wound or root abscess.Don't ingestes hydrogen peroxide.
what about tocotrienols instead of Vitamin E?
Avoid diabetes is a first step.
Dang! he was quick to the point! From now on, I'll be taking a jar full of Taurine. I want to reach the ripe old age of 50!
I always believed that this was exclusively a cat problem. Other mammals were thought to produce an adequate supply. In cats this deficiency causes epigenetic damage limiting their reproduction to only 3 generations. Is this what is causing increased levels of "genetic" problems.
B12 vitamin are good too, venant look younger. I take some. Tape higher than the nominal dose.
Supplementation works to correct nutrient deficiencies; however, most supplements do not work. Most brands have dangerous fillers, toxins, and additives. At one time, 95% of vitamin c made came from Roche, in NJ, That's the worst I know about other than Nestlé owning a once reputable food based supplement company. Anyway, taurine is a powerful antioxidant and reverses oxidative stress. Most powder forms are of equal quality. Consumer labs have some results, though I don't trust.
Slashes risk of death? So I am safer if I going parachuting, riding a skateboard on the edge of cliffs or swimming with sharks? I think you meant increases *longevity* by 150%
Rimon, do you think, NAC, as a precursor to Glutathione, is also not a good idea to take before 70?
Before 40 or 50yo
@larryc1616 I am not sure. Antioxidants kill off the effect of exercises bc of reducing the oxidation.
I actually used NAC + Glycine for about a year, 3-6 grams of each a day. I also measured my blood glutathione level. I didn't notice a significant change. I also can't attribute any other positive change to it.
Hi It's very good. It builds the natural antioxidant system, the opposite of vitamin E - external anti-oxidant which triggers laziness.
I thought sulforaphane built the endogenous antioxidant system while things like NAC stimulated glutathione production often in areas it wasn't needed?
@@purelife8559
NAC and Glycine are just the limiting molecules for the body to produce glutathion. I would expect the body to regulate precisely how much of it is needed in different cells. If so, it shouldn't affect exercise... much.
By the way, I utilize L-cysteine, not NAC, because I don’t want the extra effects NAC itself has.
What is the best taurine supplement people are taking with true hard facts of results ?????
Vitamins A, C, E and zinc along with Lutein w/zeaxathin is needed for eye health.
Where is the thumbnail before and after picture from?
Hi I used some app, I think "Face" something... coudn't get a website, only an App to do this. Ask chat GPT on apps that simulate aging
@@WellnessMessiah thanks
Taking Vitamin E Tocotrienols for a long time ... sad to hear it probably did more harm than good.. however I did note its positive effects mainly with libido.
I give taurine to my elderly cat. Cats and rats do not manufacture taurine in their bodies, hence eating it is essential for their survival. Humans can. I am really interested to see what you have found out about the impact on taurine supplementation on humans.
Yes I will delve into that. We do have aging symptoms, but never a lifespan study. We won't have one in the next 20-40 years I believe