Positive ANA test (antinuclear antibodies) and autoimmune diseases
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- Опубліковано 22 тра 2024
- What does positive ANA (antinuclear antibodies) test mean and what are the diseases that can have a positive ANA test. Here I explain all these possibilities.
#anatest #antinuclearantibody #autoimmunedisease
Chapters
0:00 Intro
0:40 What is the ANA test ?
01:50 Why was the ANA test ordered?
02:47 Is the ANA titer important?
03:28 ANA titers -what they mean in healthy people?
04:45 Is the ANA pattern suggestive of a specific disease?
06:21 What are the most frequent causes for a positive ANA?
06:31 ANA and autoimmune diseases
07:32 ANA and infections
08:16 ANA and medications
09:22 ANA and cancers
09:46 ANA in healthy individuals
10:20 ANA helpful tips
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👩🏻⚕️ About me:
Dr Diana Girnita is a double board certified physician in rheumatology and internal medicine. She completed a PhD in immunology, a postdoctoral fellowship at Harvard University, immunology fellowship at University of Pittsburgh and rheumatology fellowship at University of Cincinnati. Dr. Girnita graduated from the Nutrition Science course from Stanford University and a Mindfulness course from The University of Massachusetts; She is the founder & CEO of Rheumatologist OnCall, a practice focused on broadening access to rheumatology and offering patients an integrative medicine approach.
Dr. Girnita teaches patients about autoimmune disease, arthritis and also helps them customized their treatment plans to incorporate the proper nutrition, exercise and management of stress: "You have a disease, but YOU are not the disease"
* The information in this video is not intended nor implied to be a substitute for professional medical advice, diagnosis or treatment. All content, including text, graphics, images, and information, contained in this video is for general information purposes only and does not replace a medical consultation. Any comments and/or recommendations made in the comment section by anyone other than Rheumatologist OnCall does not reflect our opinion or recommendation.*
This was an excellent video! It was very informative and very easy to understand!
Glad it was helpful!
I have seen many videos, but I really enjoyed yours. It was very easy to understand. Thank you.
I'm so glad!
@@rheumatologistoncall Dr. Girnita, all my extensive autoimmune blood tests are negative. However, i have aching joints, swelling, pain, burning and cramping, fatigue, frequent low grade fever, headaches, dry eyes/throat/skin, petechial rash on my shins, and neck MRI results of spondyloarthropathy. My brand new rheumatologist has just ordered MRI of my SI joints as I have burning low back with stabbing pain in upper buttock. My labs are all normal, so what is happening?
I am so happy I found you. I am enjoying your videos. Thank you so much for this info. I have Sjogrens and I am struggling with mobility issues, severe back snd knee pain , terrible neuropathy. Your videos give me hope.
thank you!
check out my personalized program www.myarthritiswellness.com/
This was helpful, thank you!
Glad it was helpful!
I am a RA (negative RA factors) patient
ANA 1:80 speckled
Your video is helpful to the public
Thanks
I also have 1/80 ti
Thank you 😊
You're welcome 😊
Thank you 🙏
You’re welcome 😊
I got ANA positive just yesterday only an the doctor send me to test it an the result will b out soon but after I go through your video I really feel myself great an now am not worry at all thankyou so much Dr. it really help me
Thank you for watching my videos and supporting my channel!
You are very informative. I have 1:640 titer and hair loss and weightloss.i see a rhuma next month
Thank you for watching my channel!
I just got a ana test of 1.100 saying weak positive . And they wrote :
POSSIBLEANTIBODIESAnti NOR-90 (AC-10) POSSIBLECONDITIONSProgressive systemic sclerosis.
Don't have any symptoms ( only some q he's here and there and I'm 7 months postpartum) thank you in advance
Is it possible to have a 15 anti dsDNA level but IFA came back negative and AC-0
Dr Diana Girnita, I want to ask smoe suggestion for my case, my ANA IF result is 'reactive' with cytoplasmic fine speckled (AC-20) titer 1:320. Anti synthetase syndrome, polymyositis/Dermatomyositis , systemic sclerosis limited form.
And ANA profile euro-3 result is negative.
My ESR is high (41, my age 47 yo, woman), CRP 5.99
Leukocyte in sedimentation (urine) 105, blood in urine 0.75 mg/dL, leukocyte esterase 25.
My doctor diagnose me 'susp syndrome sjogren'.
Pain in joint and muscle, dryness in my eyes and mouth,
Would you pls give me suggestion?
Thank you so much in advance..
at what titer usually is lupus "definitive"? Meaning, at what dilution level will i say "this patient for sure has lupus, these are not healthy autoantibody levels"?
Hello my ana tests 1:100 4 times negative 2 times pozitive 1:100 and 1 times weak pozitive 1:100 2 times nucleolar and homogenous patern 1 time speckled patern and my hands have redness and itching puffy sometimes and sometime my foot ankle swelling sometime my foot heel swelling plantar fasciit and when my swelling is always 1 day after going another side of my body when swelling is gone a patch stay there what you prefer to me thank you
Hello, Thank you for the comprehensive explanation! Could I ask, is a borderline result for ANA, e.g. 1:160 a reason to test the whole panel, when the diagnosis is not definitive for arthritis. I have also constant low grade fevers and massive hair loss
retest for thyroid antibodies and AVISE testing
Ty for that video! Question..
What if, the ANA screening was positive.. 1:400 - humogen.
But the ELISA Screening was negative? ( the following test they do after a positive ANA)
Because None of the tested specific antibodys could be tracked. But still 1:400 Ana positive. Is that a common case?
Thank you for watching my channel!
Can speckled pattern shows in
Drug induced lupus?
Drug induced lupus SLE?
Also in Drug-induced leukocytoclastic vasculitis?
you need clinical symptoms and a rheumatologist
Could you please answer my question?
Can ANA test (IFA, 1/80, IgG) show a response of the body to a metal implant (titanium screws on the jaw)?
Is an autoimmune/autoinflammatory response can be induced by metal adjuvants and may they cause a positive ANA test result?
Or, could we say a negative ANA test means there is no response of the body to the metal (titanium) implants?
unfortunately I cant answer your specific question without a proper consultation.Thank you for taking the time to watch my UA-cam channel! I appreciate your support and interest in my content. It is always motivating to know that my videos are reaching and resonating with people like you.
Thanks again for being a part of my community and supporting my work.
I just got some bloodwork and the ANA was 1:40 , the Dr said no need to worry . It said Homogenous and lupus or RA , I guess as posibilites , I do have Hashimotos , and goiter , but my thyroid levels are normal. But Im always tired , and I lose alot of hair. I think they have given up .
Thank you for watching my channel!
1:640 Ana my c3 and c4 slightly elevated
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My results were 1:1280 speckled. That's usually high right?
Im 1:640 speckeled
My DFS70 antibody results is also very high it is 78.0 u/ml and my ana titre IIF is 640
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I have an negative ANA and a positive dsDNA ….dr says I have RA with a negative RF . Originally she said I have RA another time she says I have Lupus and sometimes MCTD . I am confused ….5 years ago I had stage 4 kidney failure , now I have stage 2
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Doctor,Are there any possible treatment to get negative ANA for positive ANA person?
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Hi, Doctor - mine came back as ANA titer 1:1260 speckled. What does this mean
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What is the meaning of POSITIVE 1:80 DILUTION
HEMOGENOUS PATTERN?
my video explains a lot!
Thank you for watching my channel!
Thank you for watching my channel!
My tests all came back negative. But I have all the symptoms of Sjögren’s. Is it possible to have Sjögren’s and get a negative test?
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@@rheumatologistoncall is it possible to have Sjogren's even though my blood tests come back negative?
I am having joint pains, muscle pains from 3 years onwards and heavy hair fall is happening from the past 6 months recently I have tested with Aso titre it came positive after that I have consulted a rheumatologist he wrote Ana test and it came Positive with 1:80
I am having severe pains in my joints and underneath feet please doctor tell me with which auto immune disease I am suffering with? Please do reply to my comment ma'am.
I’m having the same problems,it’s been 2 years for me now,a few tests of mines keep coming back positive,for me I don’t know yet,but I might have lupus
Have you had your Vit D levels checked? I have the same symptoms and my Vit D was low.
Mine came back abnormal and my vit d was very low I'm taking the vitamin and I drink the water it's call shine hopefully when I go back it will be up but yes vitamin d can make this test off
I have a positive Ana and also a 1.8 AI positive scleroderma.
My glucose is slightly high 113.
Alt and Als are high.
I have skin rash , and mild joint pain.
Doctor, what would you recommend?
THANK YOU !
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ANA Positive and Centromere Antibodies high ( lab range 0.0 - 0.9) result 6.0 What could it be?
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@@rheumatologistoncall is 6 very high on the centenmere abs
I have ana +
Anti rnp ++ 37
Sm (+) 8
Anti DNdn -
Anti DN natif iGg + 33.7 UI/mL
What is the diagnosis please?
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@@rheumatologistoncall ?
I am having 1/80 tires
What is that?
Thank you for watching my videos and supporting my channel! check my videos about positive ANA test
My wife has Antibodies positive... Can she became mother because she got miscarriage twice
hello mam myself sai from india my test report can -it be cure
my anti nuclear antibody- immunoflorescence : anti nuclear antibodies ( immunofluorescence assay ) shows Nucleolar pattern Intensity 3+ associated antigens - fibrillarin , rna polymerase , nor-90 , scl-70, ribosomal antigens clinical association - ai rheumatic disease , scleroderma , myositis , sle dilution - 1: 100
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Value
Positive
ANA results are reported as NEGATIVE, BORDERLINE, POSITIVE, and STRONGLY POSITIVE based on testing of normal patients. The table shows the percentage of normal patients with each level of ANA. The ANA must be interpreted within the clinical context of each patient. Result % Normal Population Negative 92% Borderline 6% Positive 1% Strongly Positive 1%
ANA Titer
View trends
Value
Positive = 1:320
ANA Pattern
View trends
Value
Speckled
What could this indicate?
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what about cytoplasm pattern?
Have you found any info on that? Just got positive Ana with cytoplasmic. Have no idea what pattern that is.
Hi, just got a positive ANA test Value: Positive, Standard Range Negative, Titter Value 1:40 with dense fine speckled. what a positive and negative standard range means? thanks
thank you
What if your ANA came back positive for Nucleolar 1:1280 and Speckled 1:640?
I did as well. No idea and I am freaking out
I’m speckled 1:640 serious trying to figure it out
@@jasminerogers5756 hi mines too. Im 60 and was recently on UTI meds i take norvas blood pressure pills.i been having weight loss massive hair loss n tired. So im buggin too