Chronic Lymphocytic Leukemia (CLL) - Diagnosis and Treatment- Hematology and Oncology Series

Chronic Lymphocytic Leukemia (CLL) - Diagnosis and Treatment- Hematology and Oncology Series (Part 2).
Complications of CLL or SLL
* Autoimmune hemolytic anemia (AIHA)
* Hypogammaglobulinemia -- decreased immunity
* Ritcher’s syndrome: aggressive large cell lymphoma (diffuse large B-cell lymphoma)
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[@MedicosisPerfectionalis]

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[@Mazzawak]

These videos must require IMMENSE effort to make while still succeeding in making them fun and interesting, well done sir.

[@MedicosisPerfectionalis]

Thank you so much 😊

[@Patanawakoyoutube]

Thank you so much sir🙏 I have been procrastinating for 3 weeks because I find ALL, CML, AML, CLL hard to study, but because of your videos, I am able to understand and conquer my fears🙏 thank you so much again sir🙏 you are God sent from heaven✨

[@MedicosisPerfectionalis]

Thank you so much, Cindy!

[@heyitsdiamedico5538]

Your channel is very underrated.. I will tell all my friends about your channel.. Its truly amazing ♥️

[@MedicosisPerfectionalis]

Thanks a million, dear :)

[@lauramed6654]

This guy's teaching is SOOO GOOD! THANKYOU!!

[@MedicosisPerfectionalis]

You’re always welcome 🙏

[@musicjazz7723]

I am super super proud of u 🥺🥺
I am Egyptian too and a medical student at Mansoura Manchester program for medical education
Hope u are safe and healthy!!!!
I benefit alot from u, thank u so much sir!!!! ❤️❤️

[@motazmahmoudegy2148]

Is he an Egyptian???how did u know?

[@Ra-ko1yo]

Woah , he is Egyptian!!!!

[@chrizstele5922]

@@motazmahmoudegy2148 yes he keeps saying that in his videos that egypt is his home country...

[@fatimazohraelyaagoubi6835]

your channel is saving my life Thank you Medicosis perfectionalis I LOVE YOUUUUUU

[@Sevendandra]

It will be a DAT coombs test. Also you will see spherocytes in the blood picture because the spleen will be removing those antibodies.

[@roonagy3702]

Thnx for your effort ❤️

[@valeriemiller1286]

Thank you for your education.

[@MedicosisPerfectionalis]

My pleasure 😇

[@Roon864]

Your channel helped me a lot
Thank you very much

[@MedicosisPerfectionalis]

My pleasure 😇

[@DR-rb9lv]

You are better then the best.... thanks sir.

[@MedicosisPerfectionalis]

Thanks 🙏

[@ghidaaatef8481]

You're great❤❤❤

[@ghdsds]

Your videos are amazing my friend

[@MedicosisPerfectionalis]

Thanks 😊

[@joomahabuzaid3296]

thank u

[@michael_s_hi]

Thanks!

[@MedicosisPerfectionalis]

My pleasure 😇

[@mariya5605]

Thanks

[@MedicosisPerfectionalis]

My pleasure 😇

[@mdriyaz1859]

Hi brother my father has ccl in early stage so now should do reduce this

[@MedicosisPerfectionalis]

Tallk to your doctor

[@cairotalaba1]

I saw direct comps test and I want to know what pen you use to draw and write, and thank you very much, professor.

[@MedicosisPerfectionalis]

Apple 🍎 pencil ✏️

[@ThatsWhy-]

Indeed, he is a smart professor. I love his style

[@lamazfarsi6843]

hello:
1-what different between clonal and monoclonal disorder because i noticed that acute and chronic leukemia is monoclonal and MDS is clonal
2-why is there thrombocytopenia is PBS in CML and thrombocytosis in PBS OF AML??

[@MedicosisPerfectionalis]

1- monoclonal means originating from one root (one crazy cell)...Clonal means it’s a stem cell problem that will affect several generations of different cells.
2- You switched them...It’s the opposite...CML has thrombocytosis because it’s a myeloproliferative disorder (all cell lines are increased)
AML has thrombocytopenia because the leukemic cells “crowd out” other cell lines.

[@inasali2235]

Medicosis Perfectionalis great but thrombocytopenia also occur in CML , right?

[@ApoorvaVerma2]

Do we have help group in India for CLL? where people can talk and share their thoughts.
Please share if anyone have this information🙏

[@mdrahamatullahmd4574]

Kindly give me also the address of cll help group if available anywhere so that I am also benefitted.

[@jillpuffer2740]

Can smudge cells be caused by anything other than CLL?

[@MedicosisPerfectionalis]

Yeah

[@lamazfarsi6843]

ALSO you mentioned in CML normocytic anemia in prephral BS !! you meant its nomocytic cell like in ALL AND AML?

[@MedicosisPerfectionalis]

Thanks for your question...Normocytic has only one meaning (normal cell size)...There is no such thing as nomocytic. And yes, they all have normocytic anemia because the leukemic cells “crowd out” the RBCs.

[@salwabassem6859]

Amazing ✨👌🏻

[@MedicosisPerfectionalis]

Thanks 🙏

[@mohammedamir7197]

Brilliant

[@MedicosisPerfectionalis]

Thanks 🙏

[@lamazfarsi6843]

also i want to get sure that i figure it (hyper cellular cell ) in all type f leukemia and MDS ..right?

[@MedicosisPerfectionalis]

Excellent! All of these are hypercellular (unlike aplastic anemia which is hypocellular).

[@Doctor____Z]

🎉🎉🎉big thanks

[@MedicosisPerfectionalis]

My pleasure 😇

[@noorhamed4690]

Very good information...I have question ....in leukemia leukocyte in first elevated and then decrease or what????

[@MedicosisPerfectionalis]

Why?

[@noorhamed4690]

@@MedicosisPerfectionalis I don't know.....and I want to know why this accur from you

[@MedicosisPerfectionalis]

I don’t know if that’s true.

[@heyitsdiamedico5538]

No its not like leucocytes are 1st increased then they decrease.... They are either very low (less than 5000) .. Or very high like 100000 per microlitre

[@itzelaguacate]

DIRECT COOMBS TEST!

[@nefertiti7367]

الله يدخلك الجنة

[@mashaelalasmari2475]

Nef 345 😂😂😂😂

[@mohonali-ej1sv]

Sir my lymphosite 48% but i need lymphosite under 40%. So u help & advice me for lymphosite treatment

[@MedicosisPerfectionalis]

It depends on the cause.

[@andrewami1114]

You have magic in your illustration ✨️
A follower from Egypt 🇪🇬 😊

[@MedicosisPerfectionalis]

Thank you 😊

[@kurtcurtis5585]

Are you from St. Louis??

[@MedicosisPerfectionalis]

No...I was just visiting 😊😊
Are you from St. Louis?

[@oveshp2155]

Very nice

[@MedicosisPerfectionalis]

Thank you 🙏

[@hannahrosa5485]

Thank you.

[@MedicosisPerfectionalis]

You’re always welcome 😊😊😊

[@faridaakbari7591]

Just in 4 days I think had finished all of the hematology videos on your channel. Thank you so much, Stay safe - Be happy - Study hard!!!!

[@MedicosisPerfectionalis]

Wow 🤩
That’s amazing 🤩

[@Mtz2604]

From minute 0:27 to 0:58 the audio is mute. :(

[@MedicosisPerfectionalis]

I am sorry 😐

[@Mtz2604]

@@MedicosisPerfectionalis no worries, I benefit a lot from the rest of the content. Thank you for your video

[@disujashakya]

Direct Coomb test

[@MedicosisPerfectionalis]

You’re right...That’s the answer! 👍

[@bhaveshgarg8142]

increased retic count will only be seen in stage 3 of CLL or it can present in any stage ?
the thing i want to clear is that anemia that occur in CLL at stage 3 is due to hemolytic anemia or because bonemarrow becomes innefficient eventually?

[@ThatsWhy-]

Can CLL turns to become ALL? especially from stage 3 up to 5 .

[@ThatsWhy-]

Crowded antibody-mediated destruction results in anemia, i guess

[@farjanashimu3662]

When you say,, hey guys.. It's sound good...

[@MedicosisPerfectionalis]

Thank you 😊

[@mounirsalek3421]

direct coombs test

[@MedicosisPerfectionalis]

Absolutely correct!

[@emymeni5438]

Why drict coomb why not indirect
Wa is the difference

[@MedicosisPerfectionalis]

Watch my video on: “Direct Coombs vs Indirect Coombs”.

[@krutisavani4328]

Mast

[@MedicosisPerfectionalis]

??

[@jabizebadi6982]

direct coombs test +

[@Cizbuvax]

❤❤❤

[@MedicosisPerfectionalis]

:)

[@Chrisanna123]

DAT!!!

[@MedicosisPerfectionalis]

😊😊

[@sofiaahmed3872]

M tired😞

[@MedicosisPerfectionalis]

What happened?

[@sofiaahmed3872]

I have final exam

[@deepakkumargupta9511]

direct coombs test