Chronic Lymphocytic Leukemia (CLL) - Etiology, Risk Factors, Symptoms, Signs, Diagnosis, Treatment

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  • Опубліковано 23 сер 2018
  • Chronic Lymphocytic Leukemia (CLL) - Etiology Symptoms, Diagnosis, Treatment- Hematology & Oncology Series
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    * Autoimmune hemolytic anemia (AIHA)
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    * Ritcher’s syndrome: aggressive large cell lymphoma (diffuse large B-cell lymphoma)
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КОМЕНТАРІ • 306

  • @MedicosisPerfectionalis
    @MedicosisPerfectionalis  2 роки тому +3

    💊🦠 Antibiotics Course: www.medicosisperfectionalis.com/
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  • @arlenegage9873
    @arlenegage9873 4 роки тому +46

    Im a 75 yr old women with CLL 10 yrs. Im in otherwise excellent health and suffer only minor problems with my stage 3 cancer. Im one of the lucky ones says my Oncologist☺

  • @MedicosisPerfectionalis
    @MedicosisPerfectionalis  5 років тому +7

    50 hematology 💉 *cases* - written by me: www.medicosisperfectionalis.com/

  • @itsjijai
    @itsjijai Рік тому +17

    Whenever I need some previews of new topics, I always search for your versions bc I understand them much easier. Your drawings help a lot, too. Thank you!

  • @rozash18
    @rozash18 4 роки тому +9

    Thank you for all of these amazing videos! You have a great way of making everything so clear and concise!

  • @wedeyforyou
    @wedeyforyou 11 місяців тому +6

    25k subs. Bro has almost a million now

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  11 місяців тому +1

      Thank you! It’s all because I have wonderful people like you!

    • @raneishaknight7188
      @raneishaknight7188 2 дні тому

      Over 1 million now🎉 it was interesting to watch this video and see that he was asking for 25k at one point. Goes to show that we all start somewhere 😊

  • @scarletmigrino132
    @scarletmigrino132 3 роки тому +13

    I like how you say, "Can you solve it? Of course you can". I've been feeling down for missing out a few points on my Hematology practice quiz, and it's little things like those that count. Thank you so much.

    • @christfollower5713
      @christfollower5713 3 роки тому

      Be encouraged , God bless u , all love

    • @wedeyforyou
      @wedeyforyou 11 місяців тому

      @@christfollower5713naa mate. This guy probably had a 98 instead of 100

  • @luisinha154
    @luisinha154 Рік тому +3

    you have literally saved my life with these videos! thank you so so much for making things easier to understand

  • @quyendisabino6877
    @quyendisabino6877 4 роки тому +3

    Thank you very much for being so generous in sharing your amazing knowledge!!!

  • @Mariah-ge5be
    @Mariah-ge5be 5 років тому +25

    Indeed you have made pathology easy for me 🤩👌
    Can't thank you enough for your efforts!💙

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  5 років тому +1

      Thank you so much...Please consider sharing my videos...Good luck with everything!

  • @becky5950
    @becky5950 3 роки тому +48

    tip- I always remember 'Smudge CLL'

  • @adensphotosandnotes5414
    @adensphotosandnotes5414 Рік тому

    I love you. You make me feel like I can actually solve these questions!

  • @abdulrahman_imad
    @abdulrahman_imad 4 роки тому +3

    My hematology exam was yesterday, thank for God and for you, for your videos, your kindly explanation, God bless you my bro.

  • @niharnayak6417
    @niharnayak6417 5 років тому

    Excellent explanation! Covered everything!! Thank you so much 😀😀😀

  • @nouranhassan5352
    @nouranhassan5352 3 роки тому

    you literally saved my life, thank you so much!!!

  • @anvayajadhav9766
    @anvayajadhav9766 3 роки тому +6

    Thank you so much! I wish our university teachers would have also taught us the way you taught !

  • @madhukardeshpande563
    @madhukardeshpande563 5 років тому +2

    We must be very thankful for ur detailed information

  • @ayeshasaeed5443
    @ayeshasaeed5443 3 роки тому +1

    Ohhh ! Seriously thanku so very much ! At the end of my session ! I found such organized , lectures ! With short tym ! Nd full knowledge ❤️❤️✨ bundles of thanks 🥺

  • @miahender7991
    @miahender7991 Рік тому +2

    I enjoy listening to your vids. Your low key sense of humor cracks me up every time! 🤣🤣🤣🤣

  • @hi99999991
    @hi99999991 3 місяці тому +1

    Hello, I am a medical laboratory scientist student and your videos have been game changing! Totally helping me through school, thank you :)

  • @mcjabaresmael9558
    @mcjabaresmael9558 3 роки тому +1

    Thanks for the generous of sharing idea.

  • @MusaMindset
    @MusaMindset 5 років тому +3

    You should also mention how to diagnose CLL, which is by flow cytometry showing a clonality of mature B cells)

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  5 років тому +1

      There is a video for that: Diagnosis& Treatment of Chronic Lymphocytic Leukemia (CLL) ua-cam.com/video/UPGi7V0vNQs/v-deo.html

  • @sameerasyed8572
    @sameerasyed8572 5 років тому +1

    I love your videos... Its making concepts very clear .. the way you are explaining it .. Keep it up n make more such videos... Thank you

  • @samilazhar8197
    @samilazhar8197 3 роки тому

    god bless you and your channel ! so informative content thank you so much

  • @celineait8131
    @celineait8131 5 років тому +3

    very very helpful you are saving my life

  • @Fr3doskin
    @Fr3doskin День тому +1

    Congrats on the 1 million subs🙏🏾❤️

  • @dr.sananesar958
    @dr.sananesar958 5 років тому +4

    U made it so simple...my concepts are much clear now, not just about CLL but other leukemia also..great 👍..

  • @mdrahamatullahmd4574
    @mdrahamatullahmd4574 8 місяців тому +1

    Today i am 59 years old battling cll since one year. I am very much afraid and anxious about this disease. I am following the advices and suggestions of my oncologist. Would any one like to like experiences etc.

  • @SHUBHAMRAJ-ff1pn
    @SHUBHAMRAJ-ff1pn 2 роки тому +3

    You are a magician. You make us understand any topics in a very short span of time 😊😊 Thank you sir 🙏🙏

  • @Farheen78601
    @Farheen78601 Рік тому +2

    Thanku sir for saving my life....i found hemat so tough but your videos r perfect like u...i love your way of teaching and your voice.😇😇😇

  • @nilupulihennayake2390
    @nilupulihennayake2390 4 роки тому

    Thnks alot.very clearly Understood ❤

  • @NuclearMedicine070
    @NuclearMedicine070 3 роки тому

    This video made pathology interesting ..!!!!

  • @catrina5808
    @catrina5808 2 роки тому

    You help me a lot in my study , thx !

  • @meghaagrawal9723
    @meghaagrawal9723 4 роки тому +13

    Stay safe , be happy and study hard .... Ty for these lines ♥️

  • @sahandsoltani6094
    @sahandsoltani6094 Рік тому

    In stage 3 and 4 of the Rai staging system we also need to have Lymphocytosis which is not mentioned in the video

  • @rodeselgac
    @rodeselgac 4 роки тому

    Thanks so much prof! It was very clear

  • @esc5561
    @esc5561 3 роки тому +3

    I love it how you make associations like lemonade and lemon for betting understanding. Great way of teaching. I appreciate this very much. Thank you!

  • @sittienorhanietampi7267
    @sittienorhanietampi7267 2 роки тому

    QUESTION. In stage 4 of CLL., Is smudged cells will still be present in the PBS?

  • @008-rara9
    @008-rara9 2 роки тому

    Can you describe about mechanism of action of Chronic lymphocytic leukemia?

  • @rutvikrana512
    @rutvikrana512 4 роки тому +22

    Teacher: "Who classified Leukaemia ?"
    Me: "Who"
    Teacher: "Yes that’s the question."
    Me: "Who"
    Teacher: "Ok! U don’t know. It’s WHO."
    Me - 🥺🥺🥺

    • @artyomgunard4491
      @artyomgunard4491 4 роки тому +4

      I'm pretty sure the owl make the classification of leukemia.

  • @kikigonzaga1336
    @kikigonzaga1336 5 років тому +1

    Fantastic explanation!

  • @wobbyyy
    @wobbyyy 2 роки тому +1

    Watching you ask for 25k subscribers when you have over 500k now! Growth!!!

  • @upasanatayade4962
    @upasanatayade4962 3 роки тому

    Sir u are awesome.thank you ✨

  • @abirkhan9940
    @abirkhan9940 5 років тому +3

    Thanks for the video

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  5 років тому

      My pleasure! Thanks for watching and taking time to leave a comment! All the best!

  • @linzyl7440
    @linzyl7440 2 роки тому

    Thank you ❤

  • @rayan01
    @rayan01 2 роки тому

    You are a life saver!!😍

  • @danae7022
    @danae7022 3 роки тому +1

    Love this video..thank you

  • @gamergirlmars
    @gamergirlmars 2 роки тому

    What about Central Nervous System Leukemia? I got diagnosed with MS and eerily enough I'm Albino with chronic anemia. I've been very, very sick my whole life, only to get worse here in recent years. Losing a ton of weight, just all the symptoms are there for some type of blood cancer. I'm not sure if I've been misdiagnosed or what. I can't hold on to iron so I get blood transfusions. This was in childhood until present. Haven't seen a hematologist in a very long time though. Blood work came back with some worrisome results at the neurologist. Currently waiting on the hematologist referral and so thus, my neurologists have decided to start Ofatumumab medicine in hopes that should my MS diagnosis be wrong, it could prove beneficial on all fronts. It's approved for leukemia's too. But It's been really hard trying to grapple with this potential diagnosis bc I honestly can't find much on it. Just that it really can mimic neurological and anemia conditions. Could you perhaps make a video on that? This video is so easy to understand and follow, hard to find!

  • @Roon864
    @Roon864 4 роки тому +1

    Thank you very much ❤️

  • @33farahhafiz56
    @33farahhafiz56 3 роки тому

    excuse me . which textbooks do you refer sir

  • @144.gali.tanmayi8
    @144.gali.tanmayi8 3 роки тому

    Thank you for video medicosisperfectionalis.can you please reply Why there hepatosleenomegaly ??? In cll.

  • @thedudeabides97
    @thedudeabides97 Рік тому

    Fantastic presentation!

  • @haveaniceday7767
    @haveaniceday7767 4 роки тому

    My brother was diagnosed with ALL diagnosed at 42 and deceased at 44. He was told at his first appointment to get his affairs in order 2 years was his life expectancy. He dies 2 years and 2 moths later on October 6, 2016

  • @hannahrosa5485
    @hannahrosa5485 4 роки тому +1

    Thank you.

  • @emmanuelniyi3870
    @emmanuelniyi3870 Рік тому +1

    Thank you so much

  • @abdurrhmanbinshmlan2670
    @abdurrhmanbinshmlan2670 Рік тому

    Can we see blast cell ( lymphoblastic ) in P•B or B•M ???

  • @eliskavavreckova373
    @eliskavavreckova373 2 роки тому

    Thank you very much 😊

  • @allet3693
    @allet3693 Місяць тому

    I searched for a rubik's cube solving method called CLL, but I only got videos about a leukemia with the same acronym

  • @bradenharris4997
    @bradenharris4997 5 місяців тому +1

    Thank you!!

  • @LOOP931
    @LOOP931 Рік тому +1

    At the beginning, u asked to reach 25000. Now 702 000 subscribers 🎉. CLOSE TO MILLION THANK U FOR EVERYTHING ❤

  • @raniaal-abdullah6629
    @raniaal-abdullah6629 4 місяці тому +1

    Thank you thank you
    you make me love pathology ❤😊😊

  • @aishwaryanagwanshi9303
    @aishwaryanagwanshi9303 3 роки тому +1

    Sir spleenic sequestration mean?

  • @Did6661
    @Did6661 5 років тому +5

    2:18 I'm a female who's only 35 (dx last year) but have had CLL since my early 20s- I actually know a girl in my online CLL support group who was diagnosed at only 18. It's a lot more common in older people, that's true, but it can affect anyone, even teens

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  5 років тому +1

      I agree...and I am so sorry you are going through this.

    • @lucylu9792
      @lucylu9792 5 років тому +1

      What support group did u join, i also joined an online support group

    • @Did6661
      @Did6661 5 років тому +2

      @@MedicosisPerfectionalis Thank you- I was diagnosed with High Risk CLL (there was a worry I had Richters Transformation for a while, but after tests & biopsies we were relieved to find it wasn't Richters). I've been doing well on an Ibrutinib & Venetoclax medical trial so, please God, I'll be around for a while 🙂

    • @Did6661
      @Did6661 5 років тому +1

      @@lucylu9792 Hi Lucy its called CLLSA 🙂

    • @lucylu9792
      @lucylu9792 5 років тому +1

      @@Did6661 i joined cllsa also my profile name is sushibruno

  • @hishamsaadallah8902
    @hishamsaadallah8902 2 роки тому +1

    Now you reach 628k not only 25 k ..
    Keep going and good luck 🤞

  • @user-jh8iz9nk9i
    @user-jh8iz9nk9i 4 роки тому

    Hello ..if you please is there any video about types if CLL as unmutated IGHv and mutated؟ it is so confusing for me ...thank s

  • @IQ24908
    @IQ24908 4 роки тому

    Thank you

  • @mhtrang1
    @mhtrang1 4 місяці тому +1

    Thankyou for all of your haematology morphology videos! Very useful n informative. Ur explanation is clear n it’s funny how u used the descriptive word for the cell: they suck! LOL 😂

  • @nabeelabidhussain8577
    @nabeelabidhussain8577 Рік тому +1

    day before exams trying to save my medical year , Prayers needed

  • @user-xd2yw1zr7n
    @user-xd2yw1zr7n 5 років тому +1

    Thanks

  • @gayathrijinesh3004
    @gayathrijinesh3004 5 років тому +1

    In ALL, AML, anemia thrombocytopenia not high risk, since they begin with blasts replacing bonemarrow. But in CLL it is high risk, since it is not replacement, but is metastatic. Please correct me if I am wrong.

    • @DentalClinician
      @DentalClinician 5 років тому +2

      CLL is low risky, CML is most riskier... Only normal B cells increased in CLL...survival rate is 7-9 yrs. In other leukemia abnormality is present in cells depending on type of leukemia, but CLL has normal mature cells

    • @gayathrijinesh3004
      @gayathrijinesh3004 5 років тому +1

      @@DentalClinician Yes sir, what i meant was, anemia and thrombocytopenia shows later stages of CLL, than its first stages. Unlike ALL,AML where they are present at the start itself.. is that correct?

    • @DentalClinician
      @DentalClinician 5 років тому +2

      @@gayathrijinesh3004 yes, that's why I mentioned CLL as "Low risky"...
      Risk = CML > AML > ALL > CLL.

  • @HafizahHoshni
    @HafizahHoshni 5 років тому +2

    Thank you so much! 28/7/2019

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  5 років тому

      My pleasure 😇.
      It has been a long time since you commented.
      How is everything?

    • @HafizahHoshni
      @HafizahHoshni 5 років тому

      Medicosis Perfectionalis everything is good ! I’m in my final year now my final examination is about one month time ! Hehe

  • @zeglammohamed
    @zeglammohamed Рік тому +1

    thank you

  • @jafarsaif182
    @jafarsaif182 Рік тому +1

    Thanks alot. ..great. .

  • @hassanabdigedi4502
    @hassanabdigedi4502 3 роки тому +1

    thanks dr

  • @Priyanka-rawat.154
    @Priyanka-rawat.154 2 роки тому

    My grandmother wbc count is 90,000 nd her blood test mentioned smudge cells....does it mean CLL?

  • @MusicalK93
    @MusicalK93 3 роки тому

    2:40 What about patients aged 14-40? Thanks.

  • @muhammadasadrazajatoi959
    @muhammadasadrazajatoi959 5 років тому +2

    U r life saver man...Love from pakistan💙

  • @michaelkino3637
    @michaelkino3637 5 років тому +2

    Best video ever made

  • @ItsMe-jr6kd
    @ItsMe-jr6kd 2 роки тому +1

    You are the best like usual ❤😍❤

  • @ayannagoring2796
    @ayannagoring2796 4 роки тому

    Can someone answer my question please? A patient with CLL that has hepatomegaly and splenomegaly, what stage is she at?

  • @zahraamohsen8352
    @zahraamohsen8352 5 років тому +2

    Amazing

  • @Faisal-ek5nv
    @Faisal-ek5nv Рік тому

    You are the best❤

  • @AsimAli-vk6oz
    @AsimAli-vk6oz 4 роки тому

    CLL only effect the lymphocyte then how anemia and thrombocypenia occur in CLL ?

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  4 роки тому

      The abnormal WBCs will "crowd out” other cell lines as discussed in the introduction videos.

  • @rathodnehal2869
    @rathodnehal2869 4 роки тому +1

    wow great 😊👍👍👌 i enjoyed 😊 your lacture

  • @noorhamed4690
    @noorhamed4690 5 років тому +1

    Thanks for this video...I have question...how can differentiate between CLL and lymphoma ow non hodgkin's lymphoma???? I want the answer becuses I have exam

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  5 років тому

      What does “ow” mean?

    • @DentalClinician
      @DentalClinician 5 років тому +3

      CLL : normal B cells but increased in PBS...Lymphoma : RS cell I.e, abnormal giant B cell (RS cell ) seen in Lymphnode biopsy

  • @ekeomodigabrielle9195
    @ekeomodigabrielle9195 11 місяців тому

    I love you Medicosis 😊❤❤❤❤❤❤

  • @masoomesadraei6695
    @masoomesadraei6695 2 роки тому

    thank u sooooo much

  • @alexanderbeck5786
    @alexanderbeck5786 2 роки тому +2

    really really good! im a German and understand everything :D

  • @isrameh9014
    @isrameh9014 6 місяців тому +1

    thank u 😍

  • @gayathrijinesh3004
    @gayathrijinesh3004 5 років тому +1

    Immunophenotype?

  • @nazmircool
    @nazmircool 4 роки тому +5

    You came a long way from trying to achieve 25k subs to having 246k subs

  • @kii9579
    @kii9579 Рік тому

    Nice explain 😊

  • @justlovehz
    @justlovehz 4 роки тому

    Please can u make cardiology playlist?! 🙆‍♀️🙆‍♀️🙆‍♀️

  • @stephiix3
    @stephiix3 Рік тому

    Watch & wait for what? For it to get worse or go away in its own?

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  Рік тому +1

      Aggressive intervention may do more harm than good when the cancer is not aggressive.

  • @SajidaMoizQamari
    @SajidaMoizQamari 3 роки тому +1

    Thank you so much for your videos. They are a great help and also fun to watch. May God bless you. Love from Pakistan

  • @Sommatix
    @Sommatix 4 роки тому

    Can CLL occur in patients at a slightly younger age? My father passed away from CLL at 50 years old and I was just curious to know.

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  4 роки тому

      It’s possible

    • @bcham7373
      @bcham7373 2 роки тому

      I was diagnosed age 33 and 48 now. I’ve been fairly stable and have not needed any treatments so far for it.

  • @dr.areenmansour6677
    @dr.areenmansour6677 3 роки тому +1

    U r great❤️

  • @aminrudwan231
    @aminrudwan231 2 роки тому

    amazing❤️✨️

  • @cametientaucoeur
    @cametientaucoeur 4 роки тому

    Informative . However, please clarify; I the last example, you have symbol for man not woman & usually found in males. Also last example stage 0 not 1? Jeanne

  • @ulfatgul868
    @ulfatgul868 3 роки тому

    thanks a trillion