X-Linked Pedigrees MADE EASY

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My goal is to reduce educational disparities by making education FREE.
These videos help you score extra points on medical school exams (USMLE, COMLEX, etc.)
For educational purposes only; NOT medical or other advice.
Some videos contain mild profanity and hyperbole solely used to assist with memorization. Viewer discretion advised.
Opinions are entirely my own.

[@DirtyMedicine]

The pedigree examples at the end (example #1 and #2) were not proofread by a geneticist. I made them quickly just to illustrate visually what rule #1 and rule #2 may look like on a real pedigree. Obviously the other sex offspring not included in the relevant rule might be affected, but for simplicity sake i made them non-affected in the examples. This is not intended to be used to learn the nuances of genetics, this is to get points right on test day.
TL:DR - just memorize rule #1 and rule #2 if you want to get all X-linked pedigrees correct.

[@abuilsult]

Mnemonic for X-linked Dominant:
X-linked *D*ominant = affected *D*aughters from affected *D*ads

[@aj7147]

pls make pedigree videos for ad n ar pls

[@fatmanasser9676]

thank u very much that was helpful....i have a Q .... can X-linked inhe come from a carrier? u didn't give us this example

[@ksuar8996]

Thanks Dirty!
Also shouldn't X-linked recessive be affected sons from unaffected mothers?

[@crystallemmon2830]

Thank you !!! This made it easier to remember @@abuilsult

[@a-fitness]

I usually think Dad-Daughter->Dominant (DDD). Thank you for the video.

[@SaravanaPrathap]

Thank you. It was helpful 👍🙂

[@somtochukwusylvesterngini1766]

thanks

[@anshika_agrawall]

It helps

[@basabeebora8916]

Good one! 👌

[@MedicalBroadcast]

Excellent

[@pulsator8221]

I've been confused about x-linked pedigrees for a while, thank you for making this so clear.

[@migs6869]

Damn you made something thats usually really complex to understand, easy thanks man !

[@karineeskandar1352]

Awesome as usual... Happy 2020, Dirty! And good luck for all the ones that are taking the test this year.

[@dominickbo5799]

since most of the people nowadays perform ASMR video, It is helpful to use it in MB exam:
ASMR;
Affected
Son
Mother
Recessive

[@19depression]

This was so helpful. Thanks a lot Dirty !!

[@teejaygauhar6826]

Excellent and I think the most easiest way to overcome in understanding x linked diseases

[@jendeh1000]

Excellent Video, thank you.

[@scoobyboobydooby]

This video is great! Can you make one for AR and AD please?

[@eddsygarcia]

this helps me understand the X linked pedigree! thank you!

[@RedandWhite26]

Thank you so so much for making this video!!

[@zildjianmirra]

Thank you so much! God bless you!

[@adamelias8082]

thanks a lot. I was really struggling, I really appreciate your tips.

[@tonimahan7235]

Thank you so much ! Exam in two hours I needed this

[@nidan6934]

Please do explain the CARRIER GENE phenomenon too for XD and XR scenarios

[@yunadunno3399]

Awesome video! Thanks for the explanation:)

[@KeabetsoeMmabatho-zr3xe]

This was the simplest version ever❤thanks DDF😅😅

[@Siriseviltwin]

This was so helpful, thank you so much!

[@emmanuelessel8650]

Best explanation

[@syedhasanraza2334]

please also explain the chance of carrier carrying the gene , most of the quests are also related to this c

[@SuyashJ]

Please make one on AR and AD too please!!

[@aj7147]

plssssss

[@monika246]

Yeah please please please🙏🙏🙏🙏

[@scoobyboobydooby]

Patiently waiting 😭

[@carolo6098]

Still waiting 😢

[@ezrabuckman2843]

God bless you

[@fatimak2729]

you're amazing.Thank you

[@HockeyGuy_in_STL]

Brilliant!

[@justinelargo6752]

Hi, is this only applies from 1st generation to second one usually? or it is also applicable from 2nd generation to third one and then from third to fourth?

[@timothyguo2668]

nice and clear. easy to understand!

[@1001GV]

Amazing 😻

[@PowderChaser]

Perfect!!

[@satyasankalpapanigrahi9416]

Thanks for this quick revision shot on Mendelian disorder traits in the Pedigree chart.
Thanks from India 🇮🇳. Post more of this ❤

[@noneofyourbusiness8748]

I did not get it in class and i expected it to be like super hard but it’s literally so easy! Thank u

[@sarahm8557]

right?!

[@saumyajoshi8088]

Amazing

[@demoonopinion2777]

awesome video as usual

[@KhardhyBhanks]

All the way from Ghana 🎉😊

[@arifshah2115]

V nice explanation

[@abdulrahmanenayeh3045]

you made a mistake making the pedigree in the middle at minute 4:03 the sons should be dominant X and recessive X not both dominant. But other wise this is great. Thanks

[@ahadabdul2795]

Super easy concept I have ever watched thaks to you for your beautiful concepts helping ❤love from Ahad side ❤😊

[@KhardhyBhanks]

I subscribed because u made it so easy for me now😭😭

[@camiloguillen2177]

YOU ATE!!!

[@hollywan8082]

Thank you so much for this video! It helped a lot! I wish I watched this video earlier

[@lstrawaya6403]

Thank you so much 😊

[@mollytheyorkie-poo7514]

You are a godsend thank you

[@ChristinaAaliyah]

Soo helpeful!

[@lazymedic5988]

About question 1 that u put..wasn't that autosomal dominant inheritance ???

[@Girlypop177]

this is so rad thank you

[@usmanwisa3386]

How we know whether its x linked or autosomal?

[@tristbaeza260]

Thank you

[@usmleislife3396]

Can u make video on confidence interval and hypothesis testing for biostat

[@shaymaahassan9708]

جزيت خيراً

[@Shmo7e]

YOU REALLY HELPED ME ALLOT , THANK YOU SO MUCH

[@dulcetoralba1868]

You are theee best i love u. Thank u sooo much

[@yasmin90s]

thank you!!

[@CarolinaL2411]

FDD 🕺 MSR 🕺 FDD 🕺 MSR 🎶 🎶 my latino head already making a choreography in my head lol

[@yuxitai5639]

have a gene exam tmr, this helped me a lot. thanks for the vid!

[@aryan7767]

help me please

[@Ms.Havana7]

thank you

[@rizwankhattak5015]

thanks sir so easy lecture so so so thanks

[@insteadofthereis]

really helpful!

[@anjenikonmalo6602]

This video is MFly brilliant. 😅😅😅😅 luuuuuv it!!!!!

[@SomendraGarnayak-cn7eg]

Thanks

[@studying_myself]

I have a biology quiz tomorrow on this tyyyyy for making it really easy 💗

[@abinayam9139]

Thank u sir it's really useful heartly thank u sir

[@michaelcohen7247]

very good video 😁

[@tejaswinigadde7202]

Need more videos on genetics please!

[@AnnabelleLaibe]

Thankyouuuuu

[@IIT-jam-bg2kq]

Thankyou soo soooo sooo much ❤❤❤

[@tahanayyar1182]

In the second punnet square both of the sons have The Gene A (dominant allel) but why it’s not effecting them??

[@krin5506]

nice

[@harshilchawla574]

Wait! In the X linked recessive one the third punnet square had two homozygous recessive females. Thaat makes the female affected right?

[@ksuar8996]

Is it affected mother or carrier mother for x linked recessive??

[@xsmartaanand6822]

What is the correct option?

[@JT-vj5ce]

As a general pedigree structure/composition rule, aren't males always on the left and females are on the right in a couple that mates (ie:// example 1)

[@afnan4593]

Thank u

[@shivmahima4]

The chart displayed at the very beginning....it is Autosomal recessive, right ???

[@moob2020]

how? shouldn't it be autosomal dominant

[@hannahjiele8916]

@@moob2020 yep dominant bec all the generation got the ds.

[@Marie-ls4nb]

amazing.

[@deepalisharma8173]

Thank you 🫂

[@diona5370]

I have a pedigree where there is an affected father x wt female producing an affected daughter and unaffected son. But my professor stated all cases, autosomal dominant+recessive and x-linked dominant and recessive work here....but how cold I check for rule 2 here?

[@emb433]

Do u hv videos on how to solve all pedigrees

[@asasahtv5822]

👍👍👍

[@imranrashik7234]

Make a t shirt with dirty med logo! I wanna buy!

[@drme2399]

Thakyouuuuu❤❤❤

[@reemanazer9778]

What about carriers !!

[@speak_charlie]

👍🏿👍🏿👍🏿👍🏿

[@amyzhou3237]

love u bro

[@salleguechynnadawno.1088]

So does that mean, affected mother cannot pass the affected allele to their daughters?

[@akankshayadav465]

She does, mother shows equal inheritance while the father by transferring Y chromosome to son and X one to her daughter shows unequal inheritance. That was just an example for you to determine the possible genotype of parents in a pedigree.

[@sarasims2207]

heaven sent

[@nouribrahim9565]

So if the allele is recessive and affected sons don't come from affected mothers, can we say based on that info that the disease is not X linked? Someone please help

[@nouribrahim9565]

because this goes against what m teacher taught me.

[@selseladariz5906]

“Only Male from Uneffected parents” is also X linked Recessive???

[@princesspat5239]

I LOVEEEEEEEEEEEEEEEEE YOU

[@dafnagellman9695]

what about X-linked dominant mothers?

[@MubashraZahoor]

Where are the explanation of next types

[@SapphireZeev36]

Dads are dominant over daughters X’s.
Mothers take their sons for Recess

[@Eskolol]

Freaking entry exams into med school were harder than the med school itself :D

[@ARTDEVGRU247]

Really?

[@cutiestcat19]

Ily

[@quandaledingle5562]

00:00

[@moatazgamal34]

FDD: Father Daughter Dance

[@stevebradford3939]

it takes me 5 min to remember the diff between the circle and the square.

[@harshsatwat2749]

Sound died

[@safeabdellatef9423]

FDD
MSR
FDD
MSR

[@lowerterror7993]

yeah don't get it

[@lowerterror7993]

I think I get it now, thank you

[@ayaanmohameddaleel1355]

Thanks