Thank you very much for this informations,ive ADHD and fibromialgia (chronicles pain) itake gaba(500mg) with magnesium and vitaminB complex by night since few week .I slept better 💫
Hi David, I just found your channel and am grateful for all the thorough information you provide. I am wondering if you’ve done a video on Bromantane or have thoughts on it? I couldn’t find one, but could’ve missed it. I know Bromantane isn’t considered a “nootropic “ because of the lack of research on healthy populations, but it seems to provide many of the benefits… Thank you!!
Another Great video n content 👌 is taking GABA supplement like pharmagaba helps with OCD or ADHD (obsessive thoughts and behaviors) ? I live in Canada, how's the best way to get the supplement. Greatly appreciated 🙏
L-Glutamine has been reported to help with OCD but I have not seen any evidence that GABA as a supplement will help. You can certainly try it and see if it helps you. Try 30 mg Zinc with Vitamin B6 for hyperactivity.
Lion's Mane main benefit is boosting Nerve Growth Factor. GABA provide the anxiolytic benefits attributed to GABA and goes on to help produce Human Growth Hormone. Which is different than Nerve Growth Factor.
Could you please share your thoughts on combining lemon balm, GABA, and glycine? Additionally, I've read that taking sublingual GABA with vitamin B6 can cross the blood-brain barrier.
Synthetic GABA with niacin has been shown to cross the blood-brain barrier. Or you can use PharmaGABA which is natural and easily gets into your brain. This is what I recommend and use for sleep: 400 mg magnesium glycinate, 500 mg Tryptophan, 250 mg PharmaGABA, 500 mg Lemon Balm extract, 400 mg L-Theanine, and 20 40 mg CBD Oil.
What is the best nootropics to use for problem solving, creativity and focus I'm junior electrical technician and busy with practical tests I need an exstra help
Hey man, I have a question about this, I picked up some gaba after this video and immediately noticed effects. I was recently watching another video about gaba, this man was saying if gaba just supplemental gaba is working, it is most likely because you have a leaking gut/blood brain barrier. Now this is somthing I’ve been told I may have before and never looked into it. Do you have any insight you could offer, and if you know any natural things to help with a leaking gut? I have been doing the tumeric you made a video about too.
Andrew, I thought that was true as well but have since learned that GABA has transporters to take it across the blood-brain barrier. It is a large molecule to it helps to use a BioActive form of GABA like PharmaGABA which is grown on lactobacillus bacteria then harvested. It's the same for that you naturally synthesize in your gut and easily and quickly gets into your brain.
Side effects from using a GABA supplement are usually only due to much higher doses of GABA that what should be used. Not sure why you're getting a migraine from its use. It just sounds like it is the wrong supplement for you.
I am 37 years old. 6.2 feet tall . Iam unable to fall asleep and having disturbed sleep Does GABA, increase the height further?bcoz it increases growth harmone, i am bit scared to take GABA.please clarify. How long is it safe to take GABA as a sleep supplement ?
I've heard that iron, phyllic acid, and carnitine help with autism symptoms. Do you happen to know which forms of these substances are best suited for this scenario? Thanks in advance.
You'll have to speak with someone at UA-cam Customer Service. Because I am doing the best I can with English and have found it's hard for this brain to learn new languages.
My GABA levels are extremely low also is my glutamate so low. Serotonin and dopamine normal but in the low end of normal. Which GABA will help me? Thank you my anxiety levels are off the charts makes me dysfunctional
What about about glycine can it effectively have a positive impact on gaba modulation? Also does everything wich helps with blood circulation automatically correlate with gabaergic activity??
Studies show GABA boosts blood levels of Human Growth Hormone. Not blood circulation. And Glycine has been shown to increase the production of serotonin in the brain. Not GABA.
So supplements that boost growth hormone may not boost gaba correct fo example people taking alpha gpc experience insomnia instead ..? Also gaba is synthesized from glutamine and it is usually taken early in the day so it is a bit confusing thanks
It can be confusing. Alpha GPC certainly does not increase GABA. GABA is produced from Glutamate which is made from Glutamine. That is a longer pathway which may be why L-Glutamine doesn't make you sleepy. But PharmaGABA can help with sleep because is very effective in calming you down.
The racetams are a derivative of GABA. And each racetam has a different mechanism of action. Mostly effecting acetylcholine and how its released and used in your brain.
Hello.. When I face an audience or a problem occurs in front of me, my body trembles, my heartbeat increases, I feel difficulty speaking and I sweat a lot.. What do these symptoms indicate?
Kareem, it's a type of social anxiety from the sounds of it. I recommended Lemon Balm Extract for a guy in Silicon Valley who had the same problem and he said it solved it for him.
Pregabalin is structurally similar to GABA but does not bind directly to GABA receptors. Using GABA as a supplement should not have any effect on the way that drug works as far as I can tell when looking at the mechanism of action for each. But that's an educated guess so don't hold me to it. Someone may prove me wrong.
@@NootropicsExpert Ok, thanks very much for your answer. I’m actually down to 50mg at night and was planning to take GABA sometime in the day so they may not interact that way.
@@NootropicsExpert I've tried a lot with zero results as singles or combos for years. 1 mg of Ativan works well about every 4 hours or so and 1.5 mg in the morning. Been on Ativan since 99 and no side effects/tolerance or memory issues. Thanks for getting back
how did you find out what test? or just guessing? I am also having sleep issues I used 5htp for a month now I don't wanna use it because I found out that it may cause damage to synapses and heart valve I don't know if it i true. They said take it with EGCG but I don't wanna risk it. Since quitting unable to sleep I used to get 3 hours sleep now maybe 30 minutes if lucky :((
5-HTP will not damage synapses. But a better option is 500 mg L-Tryptophan, 500 mg magnesium glycinate, 400 mg L-Theanine, 500 mg Lemon Balm extract, 250 mg PharmaGABA and 20 mg CBD Oil and you should sleep with no problem.
I have since changed my mind about Iodine dosage. At the time I did what video naturopaths were recommending crazy high doses. But Iodine can be toxic at high doses. Most of us only need 1 mg Iodine or less per day.
@@NootropicsExpert Forgot - The stimulants don't work either. Diagnosed with a Neuropath Blockage. For decades I drank my fair share share of coffee and about 03 it did not stimulant me for some reason - ?? Cocaine may be legal in a few years in Canada, should work
Good report. Using a GABA , theanine, valerian stack. Sometimes experience the flushing and heart race , but it subsides in minutes. Thanks Bro.💯😉
great info ... as always
Glad you enjoyed it
Always great content 🖖😎
Much appreciated
Nice discussion.
Thank you very much for this informations,ive ADHD and fibromialgia (chronicles pain) itake gaba(500mg) with magnesium and vitaminB complex by night since few week .I slept better 💫
Great video.
Thanks!
Hi David, I just found your channel and am grateful for all the thorough information you provide. I am wondering if you’ve done a video on Bromantane or have thoughts on it? I couldn’t find one, but could’ve missed it. I know Bromantane isn’t considered a “nootropic “ because of the lack of research on healthy populations, but it seems to provide many of the benefits…
Thank you!!
Jen, Bromantane is not on my to do list because I cannot find any verifiable nootropic value to using it.
@@NootropicsExpert Gotchya - thank you for responding!
thanks .
You're welcome!
I love me some GABA.
Another Great video n content 👌 is taking GABA supplement like pharmagaba helps with OCD or ADHD (obsessive thoughts and behaviors) ?
I live in Canada, how's the best way to get the supplement. Greatly appreciated 🙏
L-Glutamine has been reported to help with OCD but I have not seen any evidence that GABA as a supplement will help. You can certainly try it and see if it helps you. Try 30 mg Zinc with Vitamin B6 for hyperactivity.
Is NADH supplementation dangerous for someone with high catecholamines like dopamine & epinephrine
No
Could you please do a video about skullcap😢
Thx
Hi David,
Can Lions Main Mushroom do similar to what GABA does?
Lion's Mane main benefit is boosting Nerve Growth Factor. GABA provide the anxiolytic benefits attributed to GABA and goes on to help produce Human Growth Hormone. Which is different than Nerve Growth Factor.
Could you please share your thoughts on combining lemon balm, GABA, and glycine? Additionally, I've read that taking sublingual GABA with vitamin B6 can cross the blood-brain barrier.
Synthetic GABA with niacin has been shown to cross the blood-brain barrier. Or you can use PharmaGABA which is natural and easily gets into your brain.
This is what I recommend and use for sleep: 400 mg magnesium glycinate, 500 mg Tryptophan, 250 mg PharmaGABA, 500 mg Lemon Balm extract, 400 mg L-Theanine, and 20 40 mg CBD Oil.
Picaminol is absolutely greatest.
Better than benzos that have side effects and create physical dependence.
What is the best nootropics to use for problem solving, creativity and focus I'm junior electrical technician and busy with practical tests I need an exstra help
See this video: ua-cam.com/video/TX8h5wYPCZs/v-deo.html
Hey man, I have a question about this, I picked up some gaba after this video and immediately noticed effects. I was recently watching another video about gaba, this man was saying if gaba just supplemental gaba is working, it is most likely because you have a leaking gut/blood brain barrier. Now this is somthing I’ve been told I may have before and never looked into it. Do you have any insight you could offer, and if you know any natural things to help with a leaking gut? I have been doing the tumeric you made a video about too.
Andrew, I thought that was true as well but have since learned that GABA has transporters to take it across the blood-brain barrier. It is a large molecule to it helps to use a BioActive form of GABA like PharmaGABA which is grown on lactobacillus bacteria then harvested. It's the same for that you naturally synthesize in your gut and easily and quickly gets into your brain.
Gotu kola also seems to work wonders
Hi David 👋🏾, does 5 HTP boost GABA?
@@TzoHill No
Nope. 5-HTP goes on to produce serotonin.
5 HTP boosts serotonin
@@polygon2744 thank you. Yeah I can mix it with Magnesium and L theanine for GABA 😎
David would you explain why I get an ocular migraine when taking pharmagaba
Side effects from using a GABA supplement are usually only due to much higher doses of GABA that what should be used. Not sure why you're getting a migraine from its use. It just sounds like it is the wrong supplement for you.
Nice !
Thank you! Cheers!
i started taking Ablitfy 300mg injection every month. Any suggestions what I should take to avoid damages
NAC 500 mg 3-times per day will help repair dysfunctional dopamine receptors.
I am 37 years old. 6.2 feet tall .
Iam unable to fall asleep and having disturbed sleep
Does GABA, increase the height further?bcoz it increases growth harmone, i am bit scared to take GABA.please clarify.
How long is it safe to take GABA as a sleep supplement ?
If you are using benzos you could put yourself into a coma using a GABA supplement. See my video on this channel for sleep for other options.
I've heard that iron, phyllic acid, and carnitine help with autism symptoms. Do you happen to know which forms of these substances are best suited for this scenario? Thanks in advance.
See this video: ua-cam.com/video/PWHOvbAAcK8/v-deo.html
@@NootropicsExpert
Hi David, we need a translation for the video. I can't get the translation to work.
Hi David, we need a translation for the video. I can't get the translation to work.
You'll have to speak with someone at UA-cam Customer Service. Because I am doing the best I can with English and have found it's hard for this brain to learn new languages.
Experiencing hyper vigilance and racing thoughts in the middle of the night upon waking up. Is that overactiction of sympathetic nervous system.
Could be. I suggest seeing my latest sleep video for some tips on helping you sleep.
My GABA levels are extremely low also is my glutamate so low. Serotonin and dopamine normal but in the low end of normal. Which GABA will help me? Thank you my anxiety levels are off the charts makes me dysfunctional
I use Pharma GABA and it works great: geni.us/KOYKKYL
@@NootropicsExpertthank you so much❤
What about about glycine can it effectively have a positive impact on gaba modulation? Also does everything wich helps with blood circulation automatically correlate with gabaergic activity??
Studies show GABA boosts blood levels of Human Growth Hormone. Not blood circulation. And Glycine has been shown to increase the production of serotonin in the brain. Not GABA.
So supplements that boost growth hormone may not boost gaba correct fo example people taking alpha gpc experience insomnia instead ..?
Also gaba is synthesized from glutamine and it is usually taken early in the day so it is a bit confusing thanks
It can be confusing. Alpha GPC certainly does not increase GABA. GABA is produced from Glutamate which is made from Glutamine. That is a longer pathway which may be why L-Glutamine doesn't make you sleepy. But PharmaGABA can help with sleep because is very effective in calming you down.
What about fasoracetam? I thought that increased gaba receptor sensitivity!
The racetams are a derivative of GABA. And each racetam has a different mechanism of action. Mostly effecting acetylcholine and how its released and used in your brain.
Hello.. When I face an audience or a problem occurs in front of me, my body trembles, my heartbeat increases, I feel difficulty speaking and I sweat a lot.. What do these symptoms indicate?
Kareem, it's a type of social anxiety from the sounds of it. I recommended Lemon Balm Extract for a guy in Silicon Valley who had the same problem and he said it solved it for him.
@@NootropicsExpert Thank you.. What dose of lemon balm do you recommend?
The usual adult dosage for Lemon Balm extract is 400 - 500 mg. But if that makes you sleepy then reduce the dose.
@@NootropicsExpert thank you
This is the one I use: geni.us/wbfBMhG
I want to add GABA to my noortropics but wonder if I can if I take pregabalin (just once at night now) and GABA or not.
Pregabalin is structurally similar to GABA but does not bind directly to GABA receptors. Using GABA as a supplement should not have any effect on the way that drug works as far as I can tell when looking at the mechanism of action for each. But that's an educated guess so don't hold me to it. Someone may prove me wrong.
@@NootropicsExpert Ok, thanks very much for your answer. I’m actually down to 50mg at night and was planning to take GABA sometime in the day so they may not interact that way.
I'm damaged by a medicine called Reglan. Can you please help us find a solution, we are many who suffering
Reglan is an antagonist of D2 receptors. You can use NAC 500 mg 3-times per day which helps restore dysfunctional dopamine receptors.
I have damaged Gaba Receptor sites - Various Chloride Channels no doubt. Any known fixes etc/work arounds? An ADDer
Any supplement that boosts Brain-Derived Neurotrophic Factor and Nerve Growth Factor should help.
@@NootropicsExpert I've tried a lot with zero results as singles or combos for years. 1 mg of Ativan works well about every 4 hours or so and 1.5 mg in the morning. Been on Ativan since 99 and no side effects/tolerance or memory issues. Thanks for getting back
how did you find out what test? or just guessing? I am also having sleep issues I used 5htp for a month now I don't wanna use it because I found out that it may cause damage to synapses and heart valve I don't know if it i true. They said take it with EGCG but I don't wanna risk it. Since quitting unable to sleep I used to get 3 hours sleep now maybe 30 minutes if lucky :((
5-HTP will not damage synapses. But a better option is 500 mg L-Tryptophan, 500 mg magnesium glycinate, 400 mg L-Theanine, 500 mg Lemon Balm extract, 250 mg PharmaGABA and 20 mg CBD Oil and you should sleep with no problem.
I just watched your vid on Iodine/6 months ago. Curious - Is not 25 - 50 mg/day way too much? Woops - 7 years ago
I have since changed my mind about Iodine dosage. At the time I did what video naturopaths were recommending crazy high doses. But Iodine can be toxic at high doses. Most of us only need 1 mg Iodine or less per day.
@@NootropicsExpert 1 mg as a therapeutic dose as well as maintenance? You may want to delete the old vid all things considered.
Or do an updated video is likely a better idea. But include a note on the old video with the correct info.
@@NootropicsExpert Update it as this would be the best by far, all in all
@@NootropicsExpert Forgot - The stimulants don't work either. Diagnosed with a Neuropath Blockage. For decades I drank my fair share share of coffee and about 03 it did not stimulant me for some reason - ?? Cocaine may be legal in a few years in Canada, should work
GABA and L-theanine makes me super duper lethargic
Then take them before bed.
I think Gaba work as opposite function of Glutamate
The pathway goes like this - Glutamine > Glutamate > GABA > Human Growth Hormone.
Hi could you please do a video on nicotine
ua-cam.com/video/KaHuP8nDnuY/v-deo.html
I thought GABA doesn't cross the BBB?
Dan, that is old science which has since proven not to be true. GABA does get transported into the brain.