I had difficult weeks during initial start of my Anastrozole treatment, my hip and knee pain were so unbearable and I could not walk. I’m 52 years old and I felt like I’m 80. I felt like stopping it but I knew my tumor was 95%estrogen receptor positive and 5% progesterone +. I started regular exercises, and wore compression stockings (30mmHG grade) while on my feet at work, I work long hours standing as an RN. My symptoms eased up and I felt better. However, my cholesterol is up. My doctor will recheck and we will see. So fellow anastrozole users, it gets better , hang in there
Stop living in fear, get off the poison drugs now, change your diet don t eat a bite of sugar. Eat only 20 carbs a day, no milk or sugar ( white sugar) no grains pasta or rice.
I needed to hear this. Started the med in January along with bone infusions. Can hardly walk due to pain. I’ll give it more time as I was thinking of quitting meds.
Did letrazole w zometa infusions for a year, suffered massive bone pain and developed arthritis in one hand. Changed to anastrazole w zometa infusion (every 6 months) instead. Slighly better but still bone pain, esp after infusion. Also 2x to emerg w flashing lights in my eyes which turned out to be vitreous detachment (yes, can be related to anastrazole) and needed laser treatment to shore that up. Have gained 40 lbs and excercise is torture. My oncologist blames everything on age, and is not helpful. I feel 10 years older than when I started meds. Conflicted on what to do but we have to make choices. I used to be in superb shape, a gym bunny. Now live in fear of breaking bones and hobble down stairs.
That's why I didn't answer would never take it. My oncologist practically cursed me said you're going to drop dead if you don't take it I said so are you we're going to die one day but I didn't take it cuz I've already had two holes in my macula detached retina no way was I getting all that s***. I'm sorry that you are going through severe eye issues. I hope and wish you the best .
I would just like to add my experience: I started on Letrozole 8 months ago, and have had NO discernible side-effects. So it can happen! I have increased my level of exercise, which has had the added benefit of keeping my weight steady. (I have always watched it.) I am not intending to boast or dismissing others' problems, but maybe hoping to reassure those who might be anxious before they start on an AI. You may be lucky!
Really pleased that you are able to tolerate the drug, but my gut is telling me a big fat no even though I know I shouldn’t make assumptions. Terrifying side effects and my cancer was caught early. In the middle of 9 radiation sessions now.
16:52 This video left me speechless. I felt as though you were talking to me only. Two days ago I was at my wits end due to experiencing ever single side effect you mentioned, including osteoporosis … this last one really got to me. So I called my good doctor and told her I’m stopping the exemestane .. I can’t do this anymore. She talked me into taking a 2 week break and that I might consider Tamoxifen, because it’s kinder to the joints and bones. So, because of all your wonderful info, I’ll give it a go. What are your thoughts on receiving Prolia while on Tamoxifen? Research on it has shown that the group of women on it actually GAINED 8.8% of bone! I believe this study was done in the UK. I’m certain I’m driving my oncologist mad with all these thoughts and not knowing where to turn because I know she’s only human but it feels good talking with you because you’ve been through it. You are one of us. The fatigue and uncertainty of doing the right thing is .. I have no words. Bless you for staying strong for all of us.
Yes, the uncertainty of what to take to keep cancer from coming back vrs the potentially brutal side effects of totally blocking estrogen is nerve wracking.
I stopped, Anastrozole became too debilitating, be careful I had no symptoms, on Tamoxifen (as aches and pains came in) I had a whine so sent for a scan, showed a pulmonary embolism , off that on an anticoagulant which was horrendous caused blackouts and severe spinning out of control
Kudos to you for adding a piece of info not shared often. Heck, this was not even hinted to me except by an oncologist friend that I play tennis with. The body sometimes takes awhile to get used to the drug and symptoms may diminish over time. Time only to me meant a month or two but after three months the effects were unbearable. It took awhile to get an appointment to consider switching meds but….then I noticed some improvement. Like really? Eight months in and I’m considering sticking with Anastrozole at three months there was no joy to be had, consistently. The fact that you mentioned that symptoms may get better after a year to a year and a half gives me a clearer picture of possibilities as opposed to a finite state. It is something in the mix of my decision making and I’m glad you mentioned it. Your channel is providing nuances, nuances that I’m not coming across otherwise. My gut feeling is it is because of your personal journey with Cancer. Keep up the good work.
I try to work out why I always feel so emotional during all these Podcasts/UA-cam videos etc ... I think it's because this time last year, I had NO clue I had breast cancer; thank the Lord for mammograms. I am 63, never smoked, don't drink, eat healthily blah! blah!! Despite being caught early, Her2+/ER- and the op., tests and treatments going as planned, now on Letrazole - to date ..... no side effects ...... I guess I never imagined I would be selfishly hanging on Liz's every word, reassured by her knowledge, expertise and lived experience. How blessed are we to have such a professional in a sea of alternative this and integrated that! I shall get over myself, count my lucky stars and try to stop worrying ..... :)
@@carolshephard-blandy4261 mammograms are one of the most dangerous screening tools on the market. THEY ARE NOT SAFE but rather deliver massive amounts of radiation! This is why there is so much breast cancer today because of them. Get this, mammograms deliver 800 more times radiation than a single dental X-ray yet with a dental x-ray, what do they do? they cover you up with a lead cape from thyroid to thighs and the technician gets the hell out of the room?, right? With a mammogram, stupid women who have done absolutely no research into mammograms, much less 3D mammograms , are offering up their boobs to a stainless steel tray usually for the sole reason some mammogram advertising campaign told them to do it ( talk about mass formation psychosis) and because their insurance company was talked into paying for it by WASHINGTON LOBBYISTS. stop the madness. No wonder you have breast cancer and if you continue it will come back.
@@carolshephard-blandy4261 you should never do mammogram, doctors online say the 3D Mammograms are extremely dangerous, they recommend the softer method thermogram. Mammograms give you breast cancer, you should have figured that out by now.
Thank you Dr Liz for these videos. I was started on Letrozole right after surgery in January. Because of your information regarding the importance of exercise including weight bearing and resistance and maintaining a healthy body weight, I started a workout program as soon as my surgeon said it was ok. I have shed 50 pounds and have steadily increased my ability to use heavier weights/bands/etc. I have mild to moderate hot flashes most days which are a not pleasant but have not had the joint pain or many days of extreme fatigue so many women experience. (I still work out on those days-it does help!). My oncologist is very supportive of my efforts and agrees 100 percent with what you said . Thank you for making a positive difference. We are all different and some of us may have issues anyway but I hope women will give it a go. I know it has helped me. Anything we can do to lower chance of recurrence is good in my book
I'm almost 5 years bc survivor stage 3 estrogen positive. I will continue total 10 years zoladex and anastrozole. I don't like side effects but keep cancer away and I'm thankful be alive.Side effects:low libido,dry skin,sleep issues,stiff muscles but I walk every day 4 miles that really help and taking every 6 months zimeta prevent osteoporosis.
I’m a 77yr old female and was shocked when an MRI for Pancreas showed up a 1cm breast tumour. I’ve been on Letrozole for a week now and hopeful that it will start to shrink. Will be reassessed in 6 weeks but I have a marvellous consultant who drew me diagrams and explained everything. He was very hopeful that as it’s so small but a grade 2, not in any lymph nodes, I’ll be successful in the treatment. At my age 10 years would be great.
After some research it seems 4000iu vitamin D + 100 vit K together can help thinning of hair and bones. Definitely worth a try as it’s said to lessen inflammation throughout the body.
Just used the NHS predict there is a 4% lower survival rate for me over 15 years with my info and assuming that the lymph nodes are negative. I had surgery 2 weeks ago fingers crossed for biopsy results of sentinel nodes. Hoping I’m still low risk as I will be considering not taking them at all as I am nearly 68. Thank you for all of your videos they have been such a support to me over the recent weeks. Bless you for your kindness.
Similar - had surgery 5 years ago at 62. Predict stated 2% improvement with clear lymph nodes. Chose not to take it and so happy. An alternate proposed by Onc was annual mammograms, which I took up and have requested they continue annually.
How do we find the NHS predictor, and why did my doc not offer this? I had a lumpectomy for a 1 cm tumor and clear sentinel nodes? I did radiation, started Anastrozole and had terrible side effects which left me unable to maintain any quality of life or keep up with basic chores. Going to the grocery store required a 2-3 hr nap afterwards. Same with walking. Why am I having to take anti-estrogen drugs? I'd rather have quality of life.
@@cindy-ry3kp google 'Predict Breast’ and it will ask details of your diagnosis then will show your predicted survival rate - it is a personal decision but if your having QoL issues and your predict model indicates your at low risk ask your Onc to stop and alternately go on annual mammograms. I am certain your onc did review Predict for your case. good luck. k
Who still trusts the NHS after all of their corruption is being exposed everywhere? See Barbara O’Neill who has helped people cure stage four cancers with diet and healthy lifestyle alone .
Thank you so much Dr Liz, I appreciate your videos! I am about to start radiation now having undergone chemo & major surgeries (bilateral mastectomy & hysterectomy). I hate cancer! Thank you for your kindness & offering hope. I am praying for you.
@@colleendooley3820 do t do radiation your body is already broken due to chemo, the treatment you are going to need to deal with all the poison, especially your poor immune is shot and it’s going to be hard for a real cure like Chaparral to work. Stop with the insanity
I started with Letrozole and was switched to Anastrozole due to Letrozole continuing to raise my cholesterol. The APRN coordinated with the oncology pharmacist and the studies showed that over 50% of people on Letrozole had an increase in cholesterol levels. We will see on my next bloodwork if the switch helped.
I've been on anastrozole for 18 months. I developed high cholesterol, fatigue, and bone pain. I hope switching to it helps you. I am just going to try to hang in there until my 5 years are complete.
@@AdrienneKushner-qi6cl My cholesterol also has skyrocketed on Anastrozole after 2.5 years! I am worried it will not come down until I'm off these meds! 5 yrs total on Endocrine therapy for me was last month but my new oncologist says that staying on Anastrozole for 5 yrs is better at preventing recurrence I'm now taking it only 2x a week because of my research on intermittent dosing of Letrozole and Exemestane and the fact that Anastrozole has the Longest Half Life of 50-60 hrs and Letrozole is 48hrs & Exemestane is 24 hrs. My bone pain and swelling of ankles is much better and more able to tolerate! Bev My cholesterol won't be ck'd again until November but I'm talking Spirulina to help bring it down as well as more exercises and eating more fruits & veggies mostly cruciferous vegetables! www.webmd.com/diet/spirulina-health-benefits
I start my Letrozole journey this week after seeing my surgeon post op. on Thursday. Your video has been extremely useful as I could not get to a group class that offers help with exactly this information and you have answered so many of my questions and concerns. Thank you so much.
Thank you Dr. Liz for you amazing videos. I just completed surgery, chemo and radiotherapy and will start Letrozole in a couple of weeks. Your videos are extremely helpful, they cover many of the questions i often don’t have the time to ask my doctor during the short consultations
Thank you Liz for this super informative video, I'm now reassured that I've been prescribed the best combo of the drugs available these days: 7 years letrozole with ibandronic acid for 3 years to potect my bones, plus the calcium vit D supplement. Yoga is my go to weight bearing exercise, plus fast walking when I find the time (working from home full-time can make one stay seated too long)
Very useful and succinct video. I was prescribed Letrozole yesterday by the onco registrar (didn't even get to speak to the onco consultant). I was given no information whatsoever on what to expect and how to manage the symptoms so I'm glad I found this video. I'm starting taking it tonight and absolutely in dread - I hope I'm one of those with minimum side effects...
How are you getting on? Fingers crossed you can tolerate it. My oncologist wants me to take Letrozole but my gut is strongly telling me no. My tumor was 2cm, stage 1, lymph nodes clear.
Thank you Dr.O'Riordan, you answered all the nagging questions I had in my mind. I didn't understand why the cancer came back while I was on Tamoxifen. My oncologist changed all my treatments, and now I am on Letrozole, hence researching about it...I am hopeful that I will be fine. I am so grateful that I found your videos, extremely informative and positive. Thank you again.
Thank you so much Dr. Liz, I’m on year 3 of Letrozole my joints ache Like crazy. Plus I have Lymphodema in my right arm. Trying to get back into regular exercise now will add some weight bearing. I’m going watch all your videos. I’ve also got your book.
Thank you for such an informative video. I am about to start anastrozole after taking tamoxifen for the past 7 months. Hoping I dont get much side effects. Will continue watchinh your videos.
Hi Liz thanks for the information,been on letrozole for last 18 months only now getting to grips with previous cancer treatment of surgery,chemo and radiotherapy treatments.. My cholestrol and triglcerines have gone through the roof and therefore my hba1c has increased to 6.7% it used to be 5.4%.. the information has cleared my thinking and need to re-think my diet to a lower carb diet. will take on board you four recommendation you have mentioned thank you Regards Christine
Ive had large surge in BP after starting Anastrozle . I've also joint pain making it hard to walk sometime. I'm a gym member for 30 years. I've read Anastrozle stays in your system for 50 hours , I'm thinking of trying taking it every 48 hous instead of daily instead of giving it up completely .
I had a huge spike in BP too from anastazole of only one month on it. Actually frightened me. Family doc said to get off the anastazole asap and Onc said to just take a break from the med. Won’t the med make the BP climb again if I go back on it?
I've been taking just every second day about 8 weeks now. My BP is dropping now. I'm taking 2 BP meds after starting Anastrozole and it was uncontrolled despite taking them . Reducing it too every second day appears to be working.
I had stage zero insitu breast cancer. Very slow growing. Do you think I am at enough risk to warrant taking anastrozole? I have been taking it for a year. I worry about my bones and high cholesterol. Thanks for the video.
3cm tumor removed with really good margins, er/pr+. 1 lymph node with micro metastasis. Very small. The next one in line was clear. 5 days of radiation treatment. Started letrozole, had every symptom in the book. Developed carpal tunnel, both hands. Took a break for 3 weeks. Had surgery on both hands. Left and right EPL transposition, tenosynovitis release on 4 digits. left and right right radial tunnel release. Osteoarthritis in both thumbs. After on it for one year, decided enough was enough. Dexa score was a 12. I’m feeling a little better 6 months later, but I’m now looking at a knee replacement. Although anestozole, an letrozole are different, they are both Aromatase inhibitors. I felt like I would rather have quality of life than be miserable with more surgeries. I do take Turkey Tail. Please make an informed decision….btw, I’m 55.
Same here. I cannot do that to my poor body. 64. It is unbelievable this is Standard of care for us after all these years? These drugs are it?? Also, These meds do a number on our sex life! Sand paper feel is awful. Using vag estriol helps. Turkey tail causes diarrhea, I may try it again soon. Had dbl mast a yr+ ago.
Thank you for the very useful talk. I am on anastrazole and have osteopenia. I am afraid to take my calcium due known side affects like calcification of the arteries causing cardiovascular issues, I have a terrible family history. I am also afraid to take my alendronic acid tablet due to jaw necrosis, I have advanced gum disease and my dentist is against the drug for my use. I don't know where to turn. Regards Annette
Hello Dr Liz, I started with Letrazole and after two years I started having severe side effects. I then started anastrozole and after three days I had severe side effects and had to stop it. I’m now on exemestane and so far it’s a bit better. I have to have a short break once a year in order to cope with the side effects. I have two more years.
Fascinating about the possibility of cells in my blood. I've already had recurrences, 1 whilst on Tamoxifen for the 2nd time, which is.maybe why the Oncologist may keep me on Letrozole for longer than 5 years. Time will tell. Thanks for the information you provide.
Thank you, my Oncologist had none of this information for me. I recently had my 4th of 6 twice a year Zometa infusions to counter the lack of estrogen in bones.
Great video thank you so much. Had my first Zoladex last Thursday and being switched from Tamoxifen to Letrozole in next two or three weeks. Hoping it’s kind to me 🙏
This is great I wish I had this video 4 years ago! On Letrozole and only now I’m understanding the side effects. Luckily for me I’m keeping fit which helps.
I took Anastrozole for 2 + years and found my blood pressure rose dramatically during that period. GP advised me it was not a listed side effect in his reference book, yet there is a lot of info out there saying it can be. Would be interested to know your thoughts
High BP happened to me too. Family doc said to get off the Anastazole asap and onc said to just take a break from it but won’t the high BP and headaches happen again if I go back on the med? Is Letrozole known for causing high BP?
I have learned so much from your videos. I wanted to say that I’m taking Anastrozole as a preventative. I’m BRCA 2 +. So I haven’t had cancer. What are your thoughts on this?
Where in the country do you live? Some hospitals do a 'show and tell' presentation, of options for surgery for either cancer prevention or reconstructions after cancer. Search 'show and tell' for your nearest hospital. They give good advice on aftercare... wound care, infection prevention, scar minimisation etc. Information worth knowing for any surgery.
I'm also brca2 positive. I already had breast cancer and had a double mastectomy. Now I'm considering ovary removal to prevent ovarian cancer. Are you also considering it? I'm only 41 so I may wait a few years
Dr. Liz, I have learned so much from your videos. At 71 I was diagnosed with IDC. Multiple biopsies, mammograms and then surgery. Then radiation everyday for one month. I am currently on Letrozole 2.5. The muscle body aches are the worst. I’m terrified of bone density. Should I start a calcium supplement now?
Talk to your medical team about it. I've been on letrozole for a year now. Did a bone density scan in June, which showed I have osteopenia. To prevent further deterioration I now get Zometa every 6 months and take calcium supplement 3 times per week as my calcium level according to blood test is normal. It is very important to consult with your dentist before taking Zometa as it impacts dental health. The good news is that once you stop taking letrozole, the bone density goes back to what it would have been if you didn't take it. No need to be terrified, just follow the advice on bone density in this video and talk to your medical team)))
@@KTen-cm6wx get off the blockers, immediately. Just so you’ll know how unnecessary all that is on April 11 of 2024. I was diagnosed with lobular and ductal Breast cancer with lymph node involvement I refused all of their treatments to include chemotherapy radiation in 5 to 10 years of endocrine therapy not only I also refuse the bone biopsies in my spine and thyroid because that can cause cancer too . doing alternative which are painless and 100% effective with no toxicity for starters you can use chaparral do your homework look it up you can take ivermectin you can go to oxygen barometric chambers and flood the cancer cells with oxygen because cancer cells hate oxygen then you can change your diet and go on a ketogenic diet. Not only will you lose massive amounts of weight, but a way of eating that’s extremely healthy. You’re cutting out all the carbs which are your potato chips and pretzels, pasta, grains, and rice and bread and every granule of sugar and other words you’re cutting out the sugar that cancer needs to survive there is no need today in the year 2024 with the invention of, artificial intelligence that you need to be taking chemotherapy that was invented 60 years ago, it’s absurd it’s barbaric. It’s absolutely shameful and oncologist should be sued for doing harm.
I am on anastrozole, walked 2 miles every day,does gardening weight lifting.There are no pain,BUT, I have sleep issues.Every 2 hours I am awake, stayed awake up to an hour.I may get 5 6 hours nightlym
I take this injection once a month, in addition to daily doses of Tamoxifen. Is that standard? I’m in survivorship for 2.5 years. I was diagnosed with breast and lymph nodes cancer at age 47, I’m now 50. My side effects this far is brain fog, and significant fatigue. I call it a “no go of energy “, like I come to a full stop. I feel like my temperature rises, I guess hot flashes. I also have a strong IDGAS which could be age related.
Hello Dr ORiordan i love your information have your anything more on metastic bc ( my situation) am male so most info online is geared towards females I am taking letrozole and recently off ribo for a while anyway My advice to anyone in this situation is to get busy living ❤
I'm at 3.5 years on Letrozole only. Started at 59... I'm 62 now. My Oncologist checked whether I should stop at 5 years or carry on for several more. She said that the results indicate that taking it longer would not be therapeutic. Why would this be? Should I request to continue?
Thank you Dr. Liz for all the great information. Would you do a video on Mistletoe Therapy for breast cancer? What does the science say? Why is it so popular in Germany/Switzerland? Is IV or SubQ better? What brands are best (Helixor, Abnoba, Iscador)? Can it slow or inhibit tumor growth? Does it reduce recurrence? Some studies now suggest it does working along with traditional therapies. Please cover this major CAM therapy as a topic. It is getting a lot of news in the US lately too as the Johns Hopkins trial ramps up for Phase II. Mistletoe Cancer Therapy is expected to be a big part of the future of integrative oncology in the US. It is already prescribed to over 60% of oncology patients in Europe. It is the most studied alternative therapy to date. CAM therapies need more coverage and understanding. It is not typically meant to be a stand alone therapy for active cancer treatment, but rather it is a powerful adjunct therapy that boosts the immune system, strengthens the body's innate ability to heal, decreases side effects and symptoms from primary cancer treatments and generates apoptosis (death) of cancer cells. It is essentially an adjunct immunotherapy that supports the entire system through disease states. It is an extremely protective overall system aide. It may inhibit tumor growth while staving off metastasis. The latest studies are showing significant promise and the research is underway on this at Johns Hopkins Kimmel Cancer Center. But this is not a medical drug, it is an ancient plant-based medicine that has been in use since the time of the druids. This means that many aspects of what it does cannot be measured, because it works syngeristically with the system, with other medications, and with your own intuition about it. This way of being/thinking about medicine and healing is based on the principles of Anthroposophic medicine, which adhere to an underlying principal that goes unrecognized in Western medicine in terms of the body's innate ability to heal using its own inner wisdom and balancing mechanisms (homeostasis) which exist at the quantum mechanical level - none of which can be understood or examined as yet by our current gross-level modern science. Cancer is a microscopic problem, but our current science can barely understand it at the macroscopic level. In this sense, Anthroposophic Medicine (AM) flies in the face of everything we think we know based on our current post-modern science and rational/logical paradigms of Cartesian dualism based intellect; which is often so caught up in materialist reductionism, that these aspects (somatic wisdom for example) are not only misunderstood, they are altogether missing. It will be up to the user to find their own unprescribed, unpremeditated meaning and value in the esoteric aspects of AM, when they choose to embark on the mistletoe journey. This is a different kind of wisdom. Embrace it if you can. It is beyond words and data. This information is only a sign post to point the way to this path. Read more >> Anthroposophic Medicine, Integrative Oncology, and Mistletoe Therapy of Cancer academic.oup.com/.../chapter-abstract/303410701... The Future of MT and Integrative Oncology ua-cam.com/video/ll7mhjwkh20/v-deo.html
@@DrLizORiordan Thanks but it is not meant to treat cancer. It is an adjunct therapy meant to help the system get through cancer. It reduces symptoms of cancer treatments like chemo and it helps promote apoptosis. Don't conflate this with being a clinical cancer treatment, no one is is saying it is that. But it is a powerful adjunct therapy. It is the most widely studied and prescribed adjunct therapy. Thousands of Germans, 60% of German cancer patients are on this, are on it for good reason. President Ronald Reagan and actress Suznne Somers both used it. Please learn more about the amazing history of this CAM option (dating back to the druids) and explore this more before you speak out on this. Not all complemntary alternative medicines (CAM) are just bunk to be pushed aside. Mistletoe Therapy is now in clinical trial at Johns Hopkins in the US. It just past Phase I. There is a scholarly and peer-reviewed report published by AACR available as open access online, just google it. It will be soon coming on board in the US as a powerful complementary therapy. It is worht noting and doing a full program on. I hope you will do ore than brush it aside. Your takes need to include more CAM options imho. There isnow enough evidence-based science to show that CAM options are (not as primary treatments) but in combination with clinical treatments should be noted and not brushed off. That's old school imho. And Dr. Liz you ar enot old school!Right!
Dr Liz. Just read lovely article about you in Woman and Home. You are an inspiration. I had ducal cancer 20 years ago. Recently developed a tubular cancer in the other breast. It’s hard to get much information as it’s relatively rare. I had a lumpectomy and node removal. It was 8 mm clear margins and clear nodes. Hormone positive but her negative. I’m having radiotherapy next week. However I’m questioning whether I should take the hormone blockers or not as I’m 68 and already have back and joint pains. If I was younger I wouldn’t hesitate but at this age I want some quality of life. I would appreciate an opinion. I gather the type I have is slow to grow and spread.
Does anyone know if Letrozole can cause kidney problems? My cholesterol is slightly elevated, Triglycerides high, I have no HTN and am pre diabetic with HgbA1c of 5.8. Now spilling protein, urine ACR 252, and 6 most ago was 52... What next? So disgusted. I've been on AI for 6 yrs and 8 months. What predictor tool for continued AI do you recommend? Thanks for the great info and help you provide to us. Stage 1c or 2a, no node involvement.
I want to avoid any anti oestrogen medication and go back on my HRT after my lumpectomy. I've been reading the book Oestrogen Matters and I wondered what your thoughts are on this please Dr Liz? It seems to suggest great outcomes from doing this
Anastazole after one month made my blood pressure go very high. Doc said stop the med (family doc and onc). Should I go back on it? The drug also gave me headaches which I have never had. Also, could barely walk from joint and muscle pain. Does Letrozole have the same bad side effects? I worry not taking an aromatase inhibitor. I have mucinous breast cancer, grade 1, stage one, SNB negative. Oncotype 10. Please help!
Thank you Liz for your wonderful videos and podcast. I am also a health care worker with an aggressive BC and am navigating the maze of treatment options. I will finish Kadcyla in March and then start an AI. Your videos have been so helpful in providing sound information. Could you discuss how CDK inhibitors work and who should take them? I am also looking for more information on Ki67 and how that might impact treatment decisions. Your story has inspired me not to beat myself up for not detecting my breast lump sooner and encouraged me to continue moving forward and not looking back!
thanks a lot dr liz you really understand the pain we go through it was a big help for me i live in canada and cold weather doesnot help so every day i use heat hat and helps for the headacke and light excersise every morning help my join paint a lot drinking milk cheese and butter small piece everyday give the energy i cany go gem but i lift the 2 pond everyday with my 2 hand and i turn my wrist in different way with lifting overal abouth 1 hour per day and15 minuts walk in evening .i am in my second year of taking latrazol and i feel stronger apreciate for all detailexplanation and takecare.
Thank you doctor, what is the risk of recurrence after surgery, chemo and radiation? When having taken all these treatments and scans show no sign of cancer why take Anastrozole daily to destroy health. Why not take hormone therapy every other day since the drug remain the body 30-60 hours. In my case radiation therapy affected my thyroid gland which increased my fatigue.
Thank you so much. Such an informative video. I was on tamoxifen for just over three years until my hysterectomy and am now on letrazole for the remaining just under two years. Is that right, or should I have longer on it? Thanks
You mentioned a video to look for on your channel on Exemestane. Struggling to understand mostly because professionals are not making a differentiation and I can see that there is. The fact you mentioned the non steroidal as reversible brings me to my concern over switching to Exemestane. Why am I looking at options to ask my oncologist? My cholesterol levels have jumped with Anastrozole plus I have Pagets of the bone. My understanding is that Exemestane threatens cardio issues as opposed to bones. Being post menopausal, I also wonder about if Tamoxifen is less taxing on bones although 20 percent less effective at staving away cancer reoccurrence. My bone health is getting worse but not at a clip although my spine has improved. I was already on a course of Zoledronic acid and up to getting breast cancer I was steadily improving. I play tennis daily! My guess is you haven’t gotten to this video yet, but if this is true these are the issues I hope you will cover. You are the best!
I was switched from Letrozole to Exemestane because the Letrozole caused massive, frequent hot flashes. The oncologist said that they were similarly effective. He told me that Exemestane can cause bone thinning, so I have had 2 bone scans, which show osteopenia. So, it's possible that there are bone thinning effects with both of them. I have found Exemestane easier to cope with because I no longer have continuous hot flashes. Now, it still happens several times per day, even after the smallest exertion. I merely pick up the broom and I am sweating before I do anything with it. I am allegedly taking calcium, vitamin D and vitamin K to manage the osteopenia. (I forget frequently). I won't know if my bones are getting thinner or stabilising for another 12 months. I still get awful bone pain, but I tell myself it's a small price to pay for several years' peace of mind. My oncologist told me that my cancer was massively addicted to oestrogen; several times more oestrogen positive than most patients. Hence the effort to deal with it. I find myself worrying (when I remember that I had breast cancer) whether it will come back once I discontinue the hormone blocker. Interestingly, I developed terrible pain in my feet. This prevents me from standing more than a couple of hours each day. My GP says it might be bone spurs. I'm supposed to get an Xray and then a referral to a podiatrist. I find myself wondering, if the hormone blocker causes bone thinning, how can I grow extra bone on my feet? Hopefully some of this helps.
@@katykircher7413with so many decisions at the beginning this conundrum of whether to switch up meds seems to be the last decision left! Crazy as it seems hot flashes are not the big symptom for me, sometimes a bit warm at night but that is it! (However I do adore spicy foods) My big thing is that I constantly feel hung over, and I’m not drinking. What the heck. My burning concern with Exemestane is that it creates permanent change unlike the other two, Letrozole and Anastrozole, which are reversible. Best case scenario is that I have the option of stopping at five years and insofar a state of reversibility is a big factor in deciding what I do now. And who knows if they will come up with something in the meantime else to try. I’ve found it really hard to get info on this but did arrange an appointment with the pharmacist. I don’t even know if it;s a big deal or not but am thirsty to know more. This channel has been super great at exploring nuances and I’m hoping for more. Luckily, or unluckily, I’ve got scans related to bone density because of a previous diagnosis of Paget’s of the bone. It was stopped in it’s tracks by the infusion of zoledronic acid. (Biphosphnonate…spelling). I had gotten that yearly for three years, the last given after my cancer diagnosis. There has been a slight worsening of bone density with the aromatase inhibitor after a steady improvement before. The density of my spine continued to improve in an area that supposedly tennis is good for. I play 5 times a week. So I have a previous nuclear bone scan to compare with. No big changes there. So…my next bone density scan will be in September. Decisions to perhaps add another injection will depend on that or even some kind of change of meds….like Tamoxifen. Arghhhh…. However since Exemestane is on my radar it helps to hear of your decision and experience. You are not the only one I have heard tolerated it better than one of the other inhibitors. Thanks for that.
Thank you Liz this is so helpful. I stopped taking exemestane in July after taking for almost 9 years. My hot flushes have reduced so much and I have a general feeling of well being that I definitely didn’t have when I was taking it. However, now I worry about cancer coming back, my cancer was ER+ grade 3, stage 2. My GP contacted the oncologist to check with them that it was ok for me to come off and the message came back yes. Is there anyway I can get more insight into my PREDICT results or is it likely I might get an appointment with my oncologist, do you know?
Hi Doctor, I listened and I am on exemestane. I just started along with Lupron. I was not menopausal but put into menopause. I was looking for your video about exemestane. I didn’t know it’s steroidal. I don’t want steroids, more so since I have to take for 10 years. What’s your opinion on it?
Thank you dr Liz! Do you recommend weight lifting (light weight) in the gym if I had axillary node dissection? I heard that it can increase the chance of lymphedema. Thank you
I wish you were or I knew of this when I approached my oncologist in 2020 when I was being proactive when I was told I have a long time to cross the bridge that's when I get there that my concern is I can't take anything that is not steroidal because of my lungs is there anything besides what you're putting forth in front of me anastrosol versus Lexapro and he said no there are no steroidal I how about that extreme one he knew what I meant and he said no that's not for yo, I have to say it's a blessing that we have you and I wish I was able to write my story much clearer and my experience because I can't right well at all and I don't meanjust grammatically I'm just a horrible fragmented non-rama LOL but all my reports clearly states all these contradictions in my previous posts but you are a blessing for women and I thank you for that
This is excellent a video I now am aware of the side effects I am concerned I have hormonal positive breast cancer and I am using Anastrozole ...my point? What do I do to balance my hormones I am in menopause and 62 years old now The cancer spread to my left hip and my lower back.. please help me !!!!!
So did I and it really is a blessing. Start Letrozole after seeing my surgeon this week for BC and my husband has Pulmonary Fibrosis after having Covid and we use our wonder machine every day. Doesn't have to be an expensive one (we're pensioners) ours cost £200 from Amazon.
Thank you fir your clear explanations. After 10 years on Anastrozole then what? ( 8cm lobular tumor, 28/32 lymph nodes positive) afraid it will return if anastrozole stops) seeking advice!
I am on Letrozole but about to add ribociclib. It is designed to interfere with the cells’ growth cycles. I need an EKG and blood work baselines because of potential heart and other side effects from the drug. Adding another drug is really frightening.
Hi, Thank you for your amazing videos Dr O’Riordan. I take a 60ml cold pressed Immunity Support turmeric shot supplement from the Tumeric Co, containing Organic tumeric root, ginger root, vitamin C (1000mg) and D3 (3000iu) and am on Tamoxifen (for 2 years after a E positive breast cancer, a lumpectomy and radiotherapy). I had no idea the tumeric could interfere with the tamoxifen. Should I stop taking it? My lump was grade 2 I think. Also should I switch to Anastrozole now? I think I’m low risk of reoccurrence but I’m scared it might come back somewhere else. I’ve cut right back on alcohol, I exercise most days and am a healthy weight. I’m 57. Thank you so much. Ollie
Thankyou for making such informative videos. Pls guide me on below case. My mother is 71 years old and had undergone mastactomy last month. Post surgery on biopsy 2 tumors were identified. One of 1.2 cm invasive with ductal and lobular growth and second tumor of 2cm encapsulated pepellary carcinoma. All nodes are clear. On IHC both tumors are strong ER+ PR+ (8/8) and her 2 neu equivocal which is later negative in Fish test. She is on insulin as diabetic and hypertention. Pls guide now what further treatment she would require. Thanks in anticaption of the same
How do I know if I am still peri menopausal or in the full blown menopause? 3 years ago I had a mirena coil for heavy periods and started HRT then developed hormone hungry stage 2 breast cancer so had to stop the HRT and remove the coil. I have watched your videos and I have been advised to have radiotherapy and hormone treatment for 5 years but how do I know I’m on the right drug?
I am on ovarian suppression and anastrazole for stage 2 premenopausal breast cancer. My estradiol level is 19. Is that normal? I thought it was supposed to be less than 5?
I was diagnosed with sever carpel tunnel in both wrists prior to my breast cancer diagnosis. I have had 2 rounds of steroid injections to manage the pain. I had my lumpectomy last year and then finished my radiation treatment in November. I am currently on Letrozole for the next 5 years - although it causes sever nausea so I only take it 3x a week currently. My oncologist wants me to gradually increase this if I am able. My question is, does Letrozole make my carpel tunnel worse? I have read that Letrozole can cause carpel tunnel but I have not found anything about managing both carpel tunnel and breast cancer. Thank you!
I had 2.3cm her2+ive bc... treatment was 6 rounds of TCH, surgery plus one lymph node which was clear, the cancer had reduced to 1.3cm at time of surgery! Then 19 radiation treatments and the 14 rounds of Kadcyla and now at the 10th round (its awful stuff too) .... There was a trace of er positive and the oncologist has me listed to start letrozol soon after the targeted chemo, my body is struggling with pain all and need a break from treatment as 18 months is hard on body! My question for you, if I have only a trace of oestrogen does this warrant a AI?!?! I am 57, had a hysterectomy at 50 and now post menopause.... what are you thoughts please? 4:09 ! 4:57
At minute 5 you say you had a recurrence with Tamoxifen. My oncologist recommends it to me. How high in percentage is the benefit of taking Tamoxifen? Do those calculators predict or adjuvant online give answers to this question?
Can you please address the use of vaginal estrogen for dryness? I have been on it for years, long before my BC diagnosis due to post menopausal dryness (I'm 63). Moisturizers did very little. I'm stage 1 (invasive dcis with 4-6 mm), grade 1. I was diagnosed in the beginning of 2023 and had a lumpectomy, radiation, and Letrozole. Im still using vaginal estrogen (vagifem) because i don’t know what else to do. I had a bad case of vaginal atrophy long before getting BC. I'm scared!
BC is scary. I also experience PMD. My gynecologist prescribed VE for dryness & irritation a few weeks before my BC diagnosis. A wee internal voice told me to delay starting the VE. Once my biopsies came back ER+ I called the gynecologist to ask if starting VE was a good idea. She told me not to use it. Everyone is different. Please check in with the doctor who prescribed VE and your oncologist to help make the best choice for you. Well wishes on your journey.
@muniratjunaid8887 thank you! Best wishes to you, too. I tried the Mona Lisa laser last February and it has made a HUGE difference - better than thd estrogen I was taking. I'm off estrogen now.
This so helpful and explained well , i got her2 positive breast cancer grade 1 ,i have had a mastectomy and my oncologist put me on Anastrozole, but have been suffering from real bad bone pain and Neuropathy in my hands and wrist, so he told me to stop taking Anastrozole and has put me on exemestane ,i looked into this and its a steroid , i really dont like taking steroids as they cause extreme weight gain ,so im worried about taking them ,im still suffering from bone pain and have been of Anastrozole for nearly 3 months, would i be better just going back onto them ? Not sure if i can risk the other medication
I had difficult weeks during initial start of my Anastrozole treatment, my hip and knee pain were so unbearable and I could not walk. I’m 52 years old and I felt like I’m 80. I felt like stopping it but I knew my tumor was 95%estrogen receptor positive and 5% progesterone +.
I started regular exercises, and wore compression stockings (30mmHG grade) while on my feet at work, I work long hours standing as an RN. My symptoms eased up and I felt better. However, my cholesterol is up. My doctor will recheck and we will see.
So fellow anastrozole users, it gets better , hang in there
Stop living in fear, get off the poison drugs now, change your diet don t eat a bite of sugar. Eat only 20 carbs a day, no milk or sugar ( white sugar) no grains pasta or rice.
Cue…if you can’t pronounce the drug that is a sign you shouldn’t use it. Do t let the cut, burn or poison you this is criminal
Not taking it.
I needed to hear this. Started the med in January along with bone infusions. Can hardly walk due to pain. I’ll give it more time as I was thinking of quitting meds.
@@kelleywatt4167difficult choices when you have cancer and would like to live but I have to agree. Cancer is BIG business.
Did letrazole w zometa infusions for a year, suffered massive bone pain and developed arthritis in one hand. Changed to anastrazole w zometa infusion (every 6 months) instead. Slighly better but still bone pain, esp after infusion. Also 2x to emerg w flashing lights in my eyes which turned out to be vitreous detachment (yes, can be related to anastrazole) and needed laser treatment to shore that up. Have gained 40 lbs and excercise is torture. My oncologist blames everything on age, and is not helpful. I feel 10 years older than when I started meds. Conflicted on what to do but we have to make choices. I used to be in superb shape, a gym bunny. Now live in fear of breaking bones and hobble down stairs.
That's why I didn't answer would never take it.
My oncologist practically cursed me said you're going to drop dead if you don't take it I said so are you we're going to die one day but I didn't take it cuz I've already had two holes in my macula detached retina no way was I getting all that s***.
I'm sorry that you are going through severe eye issues.
I hope and wish you the best .
Watch that eye carefully
that drug is more depressing then the cancer itself... I don't know what to do anymore
I would just like to add my experience: I started on Letrozole 8 months ago, and have had NO discernible side-effects. So it can happen! I have increased my level of exercise, which has had the added benefit of keeping my weight steady. (I have always watched it.) I am not intending to boast or dismissing others' problems, but maybe hoping to reassure those who might be anxious before they start on an AI. You may be lucky!
Really pleased that you are able to tolerate the drug, but my gut is telling me a big fat no even though I know I shouldn’t make assumptions. Terrifying side effects and my cancer was caught early. In the middle of 9 radiation sessions now.
16:52 This video left me speechless. I felt as though you were talking to me only. Two days ago I was at my wits end due to experiencing ever single side effect you mentioned, including osteoporosis … this last one really got to me. So I called my good doctor and told her I’m stopping the exemestane .. I can’t do this anymore. She talked me into taking a 2 week break and that I might consider Tamoxifen, because it’s kinder to the joints and bones. So, because of all your wonderful info, I’ll give it a go. What are your thoughts on receiving Prolia while on Tamoxifen? Research on it has shown that the group of women on it actually GAINED 8.8% of bone! I believe this study was done in the UK. I’m certain I’m driving my oncologist mad with all these thoughts and not knowing where to turn because I know she’s only human but it feels good talking with you because you’ve been through it. You are one of us. The fatigue and uncertainty of doing the right thing is .. I have no words. Bless you for staying strong for all of us.
Yes, the uncertainty of what to take to keep cancer from coming back vrs the potentially brutal side effects of totally blocking estrogen is nerve wracking.
I stopped, Anastrozole became too debilitating, be careful I had no symptoms, on Tamoxifen (as aches and pains came in) I had a whine so sent for a scan, showed a pulmonary embolism , off that on an anticoagulant which was horrendous caused blackouts and severe spinning out of control
OMG, after the trauma of cancer you had more trauma. I am so sorry. It's unfair. @@L-ash777
Kudos to you for adding a piece of info not shared often. Heck, this was not even hinted to me except by an oncologist friend that I play tennis with. The body sometimes takes awhile to get used to the drug and symptoms may diminish over time.
Time only to me meant a month or two but after three months the effects were unbearable. It took awhile to get an appointment to consider switching meds but….then I noticed some improvement. Like really?
Eight months in and I’m considering sticking with Anastrozole at three months there was no joy to be had, consistently.
The fact that you mentioned that symptoms may get better after a year to a year and a half gives me a clearer picture of possibilities as opposed to a finite state. It is something in the mix of my decision making and I’m glad you mentioned it.
Your channel is providing nuances, nuances that I’m not coming across otherwise. My gut feeling is it is because of your personal journey with Cancer.
Keep up the good work.
I try to work out why I always feel so emotional during all these Podcasts/UA-cam videos etc ... I think it's because this time last year, I had NO clue I had breast cancer; thank the Lord for mammograms. I am 63, never smoked, don't drink, eat healthily blah! blah!! Despite being caught early, Her2+/ER- and the op., tests and treatments going as planned, now on Letrazole - to date ..... no side effects ...... I guess I never imagined I would be selfishly hanging on Liz's every word, reassured by her knowledge, expertise and lived experience. How blessed are we to have such a professional in a sea of alternative this and integrated that! I shall get over myself, count my lucky stars and try to stop worrying ..... :)
@@carolshephard-blandy4261 mammograms are one of the most dangerous screening tools on the market. THEY ARE NOT SAFE but rather deliver massive amounts of radiation! This is why there is so much breast cancer today because of them. Get this, mammograms deliver 800 more times radiation than a single dental X-ray yet with a dental x-ray, what do they do? they cover you up with a lead cape from thyroid to thighs and the technician gets the hell out of the room?, right? With a mammogram, stupid women who have done absolutely no research into mammograms, much less 3D mammograms , are offering up their boobs to a stainless steel tray usually for the sole reason some mammogram advertising campaign told them to do it ( talk about mass formation psychosis) and because their insurance company was talked into paying for it by WASHINGTON LOBBYISTS. stop the madness. No wonder you have breast cancer and if you continue it will come back.
@@carolshephard-blandy4261 you should never do mammogram, doctors online say the 3D Mammograms are extremely dangerous, they recommend the softer method thermogram. Mammograms give you breast cancer, you should have figured that out by now.
Thank you Dr Liz for these videos. I was started on Letrozole right after surgery in January. Because of your information regarding the importance of exercise including weight bearing and resistance and maintaining a healthy body weight, I started a workout program as soon as my surgeon said it was ok. I have shed 50 pounds and have steadily increased my ability to use heavier weights/bands/etc. I have mild to moderate hot flashes most days which are a not pleasant but have not had the joint pain or many days of extreme fatigue so many women experience. (I still work out on those days-it does help!). My oncologist is very supportive of my efforts and agrees 100 percent with what you said . Thank you for making a positive difference. We are all different and some of us may have issues anyway but I hope women will give it a go. I know it has helped me. Anything we can do to lower chance of recurrence is good in my book
Oh you are simply amazing!!!
YOU are the amazing one!!!@@DrLizORiordan
Thank you❤
Thank you for educating us and your kindness whilst you go through the cancer process yourself
I'm almost 5 years bc survivor stage 3 estrogen positive. I will continue total 10 years zoladex and anastrozole. I don't like side effects but keep cancer away and I'm thankful be alive.Side effects:low libido,dry skin,sleep issues,stiff muscles but I walk every day 4 miles that really help and taking every 6 months zimeta prevent osteoporosis.
Why don’t you take breast cancer index test which determines if 5 more years offers any benefits?
doesn't keep cancer away, just reduces re occurrence
I’m a 77yr old female and was shocked when an MRI for Pancreas showed up a 1cm breast tumour. I’ve been on Letrozole for a week now and hopeful that it will start to shrink. Will be reassessed in 6 weeks but I have a marvellous consultant who drew me diagrams and explained everything. He was very hopeful that as it’s so small but a grade 2, not in any lymph nodes, I’ll be successful in the treatment. At my age 10 years would be great.
After some research it seems 4000iu vitamin D + 100 vit K together can help thinning of hair and bones. Definitely worth a try as it’s said to lessen inflammation throughout the body.
Just used the NHS predict there is a 4% lower survival rate for me over 15 years with my info and assuming that the lymph nodes are negative. I had surgery 2 weeks ago fingers crossed for biopsy results of sentinel nodes. Hoping I’m still low risk as I will be considering not taking them at all as I am nearly 68. Thank you for all of your videos they have been such a support to me over the recent weeks. Bless you for your kindness.
Similar - had surgery 5 years ago at 62. Predict stated 2% improvement with clear lymph nodes. Chose not to take it and so happy. An alternate proposed by Onc was annual mammograms, which I took up and have requested they continue annually.
@@archkod thank you so much I will ask at my next appt x
How do we find the NHS predictor, and why did my doc not offer this? I had a lumpectomy for a 1 cm tumor and clear sentinel nodes? I did radiation, started Anastrozole and had terrible side effects which left me unable to maintain any quality of life or keep up with basic chores. Going to the grocery store required a 2-3 hr nap afterwards. Same with walking. Why am I having to take anti-estrogen drugs? I'd rather have quality of life.
@@cindy-ry3kp google 'Predict Breast’ and it will ask details of your diagnosis then will show your predicted survival rate - it is a personal decision but if your having QoL issues and your predict model indicates your at low risk ask your Onc to stop and alternately go on annual mammograms. I am certain your onc did review Predict for your case. good luck. k
Who still trusts the NHS after all of their corruption is being exposed everywhere? See Barbara O’Neill who has helped people cure stage four cancers with diet and healthy lifestyle alone .
Thanks a lot Dr. i really appreciat .you answer all my question better than my oncologist i pray for your health .
Thank you so much Dr Liz, I appreciate your videos! I am about to start radiation now having undergone chemo & major surgeries (bilateral mastectomy & hysterectomy).
I hate cancer!
Thank you for your kindness & offering hope. I am praying for you.
@@colleendooley3820 do t do radiation your body is already broken due to chemo, the treatment you are going to need to deal with all the poison, especially your poor immune is shot and it’s going to be hard for a real cure like Chaparral to work. Stop with the insanity
I’m sooooo pleased I’ve found your chanel 💕
I started with Letrozole and was switched to Anastrozole due to Letrozole continuing to raise my cholesterol. The APRN coordinated with the oncology pharmacist and the studies showed that over 50% of people on Letrozole had an increase in cholesterol levels. We will see on my next bloodwork if the switch helped.
I've been on anastrozole for 18 months. I developed high cholesterol, fatigue, and bone pain. I hope switching to it helps you. I am just going to try to hang in there until my 5 years are complete.
@@AdrienneKushner-qi6cl
My cholesterol also has skyrocketed on Anastrozole after 2.5 years!
I am worried it will not come down until I'm off these meds! 5 yrs total on Endocrine therapy for me was last month but my new oncologist says that staying on Anastrozole for 5 yrs is better at preventing recurrence I'm now taking it only 2x a week because of my research on intermittent dosing of Letrozole and Exemestane and the fact that Anastrozole has the Longest Half Life of 50-60 hrs and Letrozole is 48hrs & Exemestane is 24 hrs.
My bone pain and swelling of ankles is much better and more able to tolerate! Bev
My cholesterol won't be ck'd again until November but I'm talking Spirulina to help bring it down as well as more exercises and eating more fruits & veggies mostly cruciferous vegetables!
www.webmd.com/diet/spirulina-health-benefits
❤
I start my Letrozole journey this week after seeing my surgeon post op. on Thursday. Your video has been extremely useful as I could not get to a group class that offers help with exactly this information and you have answered so many of my questions and concerns. Thank you so much.
Thank you Dr. Liz for you amazing videos. I just completed surgery, chemo and radiotherapy and will start Letrozole in a couple of weeks. Your videos are extremely helpful, they cover many of the questions i often don’t have the time to ask my doctor during the short consultations
Super-great explanation of these drugs, how they work, and why they're prescribed! Thank you!
@@TRUTHisTRUTH70 not for everyone
@@healinhandagree! I’m terrified and my gut is telling me a big fat NO. I’d prefer a blood test and ultrasound every 6 months for 5 years.
Thank you Liz for this super informative video, I'm now reassured that I've been prescribed the best combo of the drugs available these days: 7 years letrozole with ibandronic acid for 3 years to potect my bones, plus the calcium vit D supplement. Yoga is my go to weight bearing exercise, plus fast walking when I find the time (working from home full-time can make one stay seated too long)
Brilliant video, thanks Liz. Very helpful.
Very useful and succinct video. I was prescribed Letrozole yesterday by the onco registrar (didn't even get to speak to the onco consultant). I was given no information whatsoever on what to expect and how to manage the symptoms so I'm glad I found this video. I'm starting taking it tonight and absolutely in dread - I hope I'm one of those with minimum side effects...
How are you getting on? Fingers crossed you can tolerate it. My oncologist wants me to take Letrozole but my gut is strongly telling me no. My tumor was 2cm, stage 1, lymph nodes clear.
Thank you Dr.O'Riordan, you answered all the nagging questions I had in my mind. I didn't understand why the cancer came back while I was on Tamoxifen. My oncologist changed all my treatments, and now I am on Letrozole, hence researching about it...I am hopeful that I will be fine. I am so grateful that I found your videos, extremely informative and positive. Thank you again.
Thank you so much Dr. Liz, I’m on year 3 of Letrozole my joints ache
Like crazy. Plus I have Lymphodema in my right arm. Trying to get back into regular exercise now will add some weight bearing. I’m going watch all your videos. I’ve also got your book.
Thank you, really helpful and straightforward as always ❤
You're so welcome!
Thank you for such an informative video. I am about to start anastrozole after taking tamoxifen for the past 7 months. Hoping I dont get much side effects. Will continue watchinh your videos.
Hi Liz thanks for the information,been on letrozole for last 18 months only now getting to grips with previous cancer treatment of surgery,chemo and radiotherapy treatments.. My cholestrol and triglcerines have gone through the roof and therefore my hba1c has increased to 6.7% it used to be 5.4%.. the information has cleared my thinking and need to re-think my diet to a lower carb diet. will take on board you four recommendation you have mentioned thank you Regards Christine
Thanks for the video, could we have the promised video about Exemestane please 🙏
Ive had large surge in BP after starting Anastrozle . I've also joint pain making it hard to walk sometime. I'm a gym member for 30 years. I've read Anastrozle stays in your system for 50 hours , I'm thinking of trying taking it every 48 hous instead of daily instead of giving it up completely .
I took mine once per week and still suffered from knee and other joint pain. I refuse to take another pill!
I had a huge spike in BP too from anastazole of only one month on it. Actually frightened me. Family doc said to get off the anastazole asap and Onc said to just take a break from the med. Won’t the med make the BP climb again if I go back on it?
@briggettecammett6181 yes it definitely will. These oncologist can care less! Do what's best for you at the end of the day!
I've been taking just every second day about 8 weeks now. My BP is dropping now. I'm taking 2 BP meds after starting Anastrozole and it was uncontrolled despite taking them . Reducing it too every second day appears to be working.
Didn't work for me
I had stage zero insitu breast cancer. Very slow growing. Do you think I am at enough risk to warrant taking anastrozole? I have been taking it for a year. I worry about my bones and high cholesterol. Thanks for the video.
Your videos are so helpful . Thank you so much for your work❤
3cm tumor removed with really good margins, er/pr+. 1 lymph node with micro metastasis. Very small. The next one in line was clear. 5 days of radiation treatment. Started letrozole, had every symptom in the book. Developed carpal tunnel, both hands. Took a break for 3 weeks. Had surgery on both hands. Left and right EPL transposition, tenosynovitis release on 4 digits. left and right right radial tunnel release. Osteoarthritis in both thumbs. After on it for one year, decided enough was enough. Dexa score was a 12. I’m feeling a little better 6 months later, but I’m now looking at a knee replacement.
Although anestozole, an letrozole are different, they are both Aromatase inhibitors.
I felt like I would rather have quality of life than be miserable with more surgeries. I do take Turkey Tail. Please make an informed decision….btw, I’m 55.
@@healinhand get of hormone blockers and gift your body by doing so. You do not need them, your body needs hormones.
Same here. I cannot do that to my poor body. 64. It is unbelievable this is Standard of care for us after all these years? These drugs are it?? Also, These meds do a number on our sex life! Sand paper feel is awful. Using vag estriol helps. Turkey tail causes diarrhea, I may try it again soon. Had dbl mast a yr+ ago.
Thank you for the very useful talk. I am on anastrazole and have osteopenia. I am afraid to take my calcium due known side affects like calcification of the arteries causing cardiovascular issues, I have a terrible family history.
I am also afraid to take my alendronic acid tablet due to jaw necrosis, I have advanced gum disease and my dentist is against the drug for my use. I don't know where to turn. Regards Annette
Very informative as always. Thanks you Dr💗
My pleasure 😊
Hello Dr Liz, I started with Letrazole and after two years I started having severe side effects. I then started anastrozole and after three days I had severe side effects and had to stop it. I’m now on exemestane and so far it’s a bit better. I have to have a short break once a year in order to cope with the side effects. I have two more years.
Fascinating about the possibility of cells in my blood. I've already had recurrences, 1 whilst on Tamoxifen for the 2nd time, which is.maybe why the Oncologist may keep me on Letrozole for longer than 5 years. Time will tell. Thanks for the information you provide.
Thank you, my Oncologist had none of this information for me. I recently had my 4th of 6 twice a year Zometa infusions to counter the lack of estrogen in bones.
😊thank you so much for these very useful information. I look forward to seeing your blog every week.
You are so welcome!
Great video thank you so much. Had my first Zoladex last Thursday and being switched from Tamoxifen to Letrozole in next two or three weeks. Hoping it’s kind to me 🙏
How did you go?💖
@@thelotusheart_I’d like to know also but alas no reply from Kate. I’m leaning towards 6 monthly blood tests and scans x
Thank you such a great and helpful information. God bless you!❤
I like your videos. I am learning a lot from you. Thanks
This is great I wish I had this video 4 years ago! On Letrozole and only now I’m understanding the side effects. Luckily for me I’m keeping fit which helps.
I took Anastrozole for 2 + years and found my blood pressure rose dramatically during that period. GP advised me it was not a listed side effect in his reference book, yet there is a lot of info out there saying it can be. Would be interested to know your thoughts
I haven’t read the full list of side effects for a while I’m afraid. What does it say on the leaflet in the packet?
High BP happened to me too. Family doc said to get off the Anastazole asap and onc said to just take a break from it but won’t the high BP and headaches happen again if I go back on the med? Is Letrozole known for causing high BP?
Thank you so much. We/I appreciate all the information
Thank you so much for sharing this extremely helpful video ❤🙏 ~ Mandy
I have learned so much from your videos. I wanted to say that I’m taking Anastrozole as a preventative. I’m BRCA 2 +.
So I haven’t had cancer. What are your thoughts on this?
Where in the country do you live? Some hospitals do a 'show and tell' presentation, of options for surgery for either cancer prevention or reconstructions after cancer. Search 'show and tell' for your nearest hospital. They give good advice on aftercare... wound care, infection prevention, scar minimisation etc. Information worth knowing for any surgery.
I'm also brca2 positive. I already had breast cancer and had a double mastectomy. Now I'm considering ovary removal to prevent ovarian cancer. Are you also considering it? I'm only 41 so I may wait a few years
Thank you so much for this very informative video.
You are so welcome!
Thanks for this video . I am taking anaztraole for my DCIS stage 1 diagnosis, just 4 months into it . The fatigue and sometimes hot flashes sucks!!!😩
Yes they do!
Dr. Liz, I have learned so much from your videos. At 71 I was diagnosed with IDC. Multiple biopsies, mammograms and then surgery. Then radiation everyday for one month. I am currently on Letrozole 2.5. The muscle body aches are the worst. I’m terrified of bone density. Should I start a calcium supplement now?
Talk to your medical team about it. I've been on letrozole for a year now. Did a bone density scan in June, which showed I have osteopenia. To prevent further deterioration I now get Zometa every 6 months and take calcium supplement 3 times per week as my calcium level according to blood test is normal. It is very important to consult with your dentist before taking Zometa as it impacts dental health. The good news is that once you stop taking letrozole, the bone density goes back to what it would have been if you didn't take it. No need to be terrified, just follow the advice on bone density in this video and talk to your medical team)))
@@KTen-cm6wx get off the blockers, immediately. Just so you’ll know how unnecessary all that is on April 11 of 2024. I was diagnosed with lobular and ductal Breast cancer with lymph node involvement I refused all of their treatments to include chemotherapy radiation in 5 to 10 years of endocrine therapy not only I also refuse the bone biopsies in my spine and thyroid because that can cause cancer too . doing alternative which are painless and 100% effective with no toxicity for starters you can use chaparral do your homework look it up you can take ivermectin you can go to oxygen barometric chambers and flood the cancer cells with oxygen because cancer cells hate oxygen then you can change your diet and go on a ketogenic diet. Not only will you lose massive amounts of weight, but a way of eating that’s extremely healthy. You’re cutting out all the carbs which are your potato chips and pretzels, pasta, grains, and rice and bread and every granule of sugar and other words you’re cutting out the sugar that cancer needs to survive there is no need today in the year 2024 with the invention of, artificial intelligence that you need to be taking chemotherapy that was invented 60 years ago, it’s absurd it’s barbaric. It’s absolutely shameful and oncologist should be sued for doing harm.
You explain very well, thanks!
Thanks for watching and subsciribing!
I am on anastrozole, walked 2 miles every day,does gardening weight lifting.There are no pain,BUT, I have sleep issues.Every 2 hours I am awake, stayed awake up to an hour.I may get 5 6 hours nightlym
I am 66, so I am not menopausal. I am post menopausal by over 15 years. But I have still been prescribed Anastrolzole.
I’m 62 and post menopausal and they want to give me Letrozole. My gut is telling me no as cancer caught early and lymph nodes clear. Feel so anxious 😬
@ What stage are you? I am stage 2.
I take this injection once a month, in addition to daily doses of Tamoxifen. Is that standard? I’m in survivorship for 2.5 years. I was diagnosed with breast and lymph nodes cancer at age 47, I’m now 50. My side effects this far is brain fog, and significant fatigue. I call it a “no go of energy “, like I come to a full stop. I feel like my temperature rises, I guess hot flashes. I also have a strong IDGAS which could be age related.
Hello Dr ORiordan i love your information have your anything more on metastic bc ( my situation) am male so most info online is geared towards females
I am taking letrozole and recently off ribo for a while anyway
My advice to anyone in this situation is to get busy living ❤
I love how you present the information.
I'm at 3.5 years on Letrozole only. Started at 59... I'm 62 now.
My Oncologist checked whether I should stop at 5 years or carry on for several more.
She said that the results indicate that taking it longer would not be therapeutic.
Why would this be?
Should I request to continue?
Could you please tell if you were offered Bisphosphonates.I am on Anastrozol and at the same time was advised to take bisphosphonete.
Thank you Dr. Liz for all the great information. Would you do a video on Mistletoe Therapy for breast cancer? What does the science say? Why is it so popular in Germany/Switzerland? Is IV or SubQ better? What brands are best (Helixor, Abnoba, Iscador)? Can it slow or inhibit tumor growth? Does it reduce recurrence? Some studies now suggest it does working along with traditional therapies. Please cover this major CAM therapy as a topic. It is getting a lot of news in the US lately too as the Johns Hopkins trial ramps up for Phase II.
Mistletoe Cancer Therapy is expected to be a big part of the future of integrative oncology in the US. It is already prescribed to over 60% of oncology patients in Europe. It is the most studied alternative therapy to date. CAM therapies need more coverage and understanding. It is not typically meant to be a stand alone therapy for active cancer treatment, but rather it is a powerful adjunct therapy that boosts the immune system, strengthens the body's innate ability to heal, decreases side effects and symptoms from primary cancer treatments and generates apoptosis (death) of cancer cells. It is essentially an adjunct immunotherapy that supports the entire system through disease states. It is an extremely protective overall system aide. It may inhibit tumor growth while staving off metastasis. The latest studies are showing significant promise and the research is underway on this at Johns Hopkins Kimmel Cancer Center.
But this is not a medical drug, it is an ancient plant-based medicine that has been in use since the time of the druids. This means that many aspects of what it does cannot be measured, because it works syngeristically with the system, with other medications, and with your own intuition about it. This way of being/thinking about medicine and healing is based on the principles of Anthroposophic medicine, which adhere to an underlying principal that goes unrecognized in Western medicine in terms of the body's innate ability to heal using its own inner wisdom and balancing mechanisms (homeostasis) which exist at the quantum mechanical level - none of which can be understood or examined as yet by our current gross-level modern science. Cancer is a microscopic problem, but our current science can barely understand it at the macroscopic level.
In this sense, Anthroposophic Medicine (AM) flies in the face of everything we think we know based on our current post-modern science and rational/logical paradigms of Cartesian dualism based intellect; which is often so caught up in materialist reductionism, that these aspects (somatic wisdom for example) are not only misunderstood, they are altogether missing. It will be up to the user to find their own unprescribed, unpremeditated meaning and value in the esoteric aspects of AM, when they choose to embark on the mistletoe journey. This is a different kind of wisdom. Embrace it if you can. It is beyond words and data. This information is only a sign post to point the way to this path.
Read more >>
Anthroposophic Medicine, Integrative Oncology, and Mistletoe Therapy of Cancer
academic.oup.com/.../chapter-abstract/303410701...
The Future of MT and Integrative Oncology
ua-cam.com/video/ll7mhjwkh20/v-deo.html
Until a trial proves that it has a significant impact on cancer survival I don’t think it should be used to treat cancer.
@@DrLizORiordan Thanks but it is not meant to treat cancer. It is an adjunct therapy meant to help the system get through cancer. It reduces symptoms of cancer treatments like chemo and it helps promote apoptosis. Don't conflate this with being a clinical cancer treatment, no one is is saying it is that. But it is a powerful adjunct therapy. It is the most widely studied and prescribed adjunct therapy. Thousands of Germans, 60% of German cancer patients are on this, are on it for good reason. President Ronald Reagan and actress Suznne Somers both used it. Please learn more about the amazing history of this CAM option (dating back to the druids) and explore this more before you speak out on this. Not all complemntary alternative medicines (CAM) are just bunk to be pushed aside. Mistletoe Therapy is now in clinical trial at Johns Hopkins in the US. It just past Phase I. There is a scholarly and peer-reviewed report published by AACR available as open access online, just google it. It will be soon coming on board in the US as a powerful complementary therapy. It is worht noting and doing a full program on. I hope you will do ore than brush it aside. Your takes need to include more CAM options imho. There isnow enough evidence-based science to show that CAM options are (not as primary treatments) but in combination with clinical treatments should be noted and not brushed off. That's old school imho. And Dr. Liz you ar enot old school!Right!
Absolutely mistletoe tinctture l take also eassiac tea kills cancer
Thank you that was really helpful
Excellent video. I'll exercise 1 or 2 days then lie around. Your video has motivated me to get moving. Thank you so much.
Dr Liz. Just read lovely article about you in Woman and Home. You are an inspiration. I had ducal cancer 20 years ago. Recently developed a tubular cancer in the other breast. It’s hard to get much information as it’s relatively rare. I had a lumpectomy and node removal. It was 8 mm clear margins and clear nodes. Hormone positive but her negative. I’m having radiotherapy next week. However I’m questioning whether I should take the hormone blockers or not as I’m 68 and already have back and joint pains. If I was younger I wouldn’t hesitate but at this age I want some quality of life. I would appreciate an opinion. I gather the type I have is slow to grow and spread.
Thank you so much!
You're welcome!
Does anyone know if Letrozole can cause kidney problems? My cholesterol is slightly elevated, Triglycerides high, I have no HTN and am pre diabetic with HgbA1c of 5.8. Now spilling protein, urine ACR 252, and 6 most ago was 52... What next? So disgusted. I've been on AI for 6 yrs and 8 months. What predictor tool for continued AI do you recommend? Thanks for the great info and help you provide to us. Stage 1c or 2a, no node involvement.
Thankyou for such an awesome video …. I’m finding weight again my biggest issue have you found that in some patients
I want to avoid any anti oestrogen medication and go back on my HRT after my lumpectomy. I've been reading the book Oestrogen Matters and I wondered what your thoughts are on this please Dr Liz?
It seems to suggest great outcomes from doing this
Anastazole after one month made my blood pressure go very high. Doc said stop the med (family doc and onc). Should I go back on it? The drug also gave me headaches which I have never had. Also, could barely walk from joint and muscle pain. Does Letrozole have the same bad side effects?
I worry not taking an aromatase inhibitor.
I have mucinous breast cancer, grade 1, stage one, SNB negative. Oncotype 10. Please help!
My family have a background about breast cancer and 1 am 45 yrs old that's why I'm very interested about your explanation
Thank you Liz for your wonderful videos and podcast. I am also a health care worker with an aggressive BC and am navigating the maze of treatment options. I will finish Kadcyla in March and then start an AI. Your videos have been so helpful in providing sound information. Could you discuss how CDK inhibitors work and who should take them? I am also looking for more information on Ki67 and how that might impact treatment decisions. Your story has inspired me not to beat myself up for not detecting my breast lump sooner and encouraged me to continue moving forward and not looking back!
I've got a video all about the CDK inhibitors - look for the playlist Breast Cancer Drugs
thanks a lot dr liz you really understand the pain we go through it was a big help for me i live in canada and cold weather doesnot help so every day i use heat hat and helps for the headacke and light excersise every morning help my join paint a lot drinking milk cheese and butter small piece everyday give the energy i cany go gem but i lift the 2 pond everyday with my 2 hand and i turn my wrist in different way with lifting overal abouth 1 hour per day and15 minuts walk in evening .i am in my second year of taking latrazol and i feel stronger apreciate for all detailexplanation and takecare.
Thank you doctor❤
Thank you doctor, what is the risk of recurrence after surgery, chemo and radiation? When having taken all these treatments and scans show no sign of cancer why take Anastrozole daily to destroy health. Why not take hormone therapy every other day since the drug remain the body 30-60 hours. In my case radiation therapy affected my thyroid gland which increased my fatigue.
Thank you so much. Such an informative video. I was on tamoxifen for just over three years until my hysterectomy and am now on letrazole for the remaining just under two years. Is that right, or should I have longer on it? Thanks
Thank you so helpful. Why did you find taking it at night is better I'd like to ask dear Liz?
Thank you so much for this importand information. I wll have a better understanding of thes medications when my oncologist prescibes one for me.
Since on anastozole cant sleep well thus coursing my BP to shoot high please advise.
You mentioned a video to look for on your channel on Exemestane. Struggling to understand mostly because professionals are not making a differentiation and I can see that there is. The fact you mentioned the non steroidal as reversible brings me to my concern over switching to Exemestane.
Why am I looking at options to ask my oncologist? My cholesterol levels have jumped with Anastrozole plus I have Pagets of the bone. My understanding is that Exemestane threatens cardio issues as opposed to bones. Being post menopausal, I also wonder about if Tamoxifen is less taxing on bones although 20 percent less effective at staving away cancer reoccurrence.
My bone health is getting worse but not at a clip although my spine has improved. I was already on a course of Zoledronic acid and up to getting breast cancer I was steadily improving. I play tennis daily!
My guess is you haven’t gotten to this video yet, but if this is true these are the issues I hope you will cover.
You are the best!
I was switched from Letrozole to Exemestane because the Letrozole caused massive, frequent hot flashes. The oncologist said that they were similarly effective. He told me that Exemestane can cause bone thinning, so I have had 2 bone scans, which show osteopenia. So, it's possible that there are bone thinning effects with both of them.
I have found Exemestane easier to cope with because I no longer have continuous hot flashes. Now, it still happens several times per day, even after the smallest exertion. I merely pick up the broom and I am sweating before I do anything with it. I am allegedly taking calcium, vitamin D and vitamin K to manage the osteopenia. (I forget frequently). I won't know if my bones are getting thinner or stabilising for another 12 months.
I still get awful bone pain, but I tell myself it's a small price to pay for several years' peace of mind. My oncologist told me that my cancer was massively addicted to oestrogen; several times more oestrogen positive than most patients. Hence the effort to deal with it. I find myself worrying (when I remember that I had breast cancer) whether it will come back once I discontinue the hormone blocker.
Interestingly, I developed terrible pain in my feet. This prevents me from standing more than a couple of hours each day. My GP says it might be bone spurs. I'm supposed to get an Xray and then a referral to a podiatrist. I find myself wondering, if the hormone blocker causes bone thinning, how can I grow extra bone on my feet?
Hopefully some of this helps.
@@katykircher7413with so many decisions at the beginning this conundrum of whether to switch up meds seems to be the last decision left!
Crazy as it seems hot flashes are not the big symptom for me, sometimes a bit warm at night but that is it! (However I do adore spicy foods)
My big thing is that I constantly feel hung over, and I’m not drinking. What the heck.
My burning concern with Exemestane is that it creates permanent change unlike the other two, Letrozole and Anastrozole, which are reversible.
Best case scenario is that I have the option of stopping at five years and insofar a state of reversibility is a big factor in deciding what I do now. And who knows if they will come up with something in the meantime else to try. I’ve found it really hard to get info on this but did arrange an appointment with the pharmacist. I don’t even know if it;s a big deal or not but am thirsty to know more. This channel has been super great at exploring nuances and I’m hoping for more.
Luckily, or unluckily, I’ve got scans related to bone density because of a previous diagnosis of Paget’s of the bone. It was stopped in it’s tracks by the infusion of zoledronic acid. (Biphosphnonate…spelling). I had gotten that yearly for three years, the last given after my cancer diagnosis.
There has been a slight worsening of bone density with the aromatase inhibitor after a steady improvement before. The density of my spine continued to improve in an area that supposedly tennis is good for. I play 5 times a week. So I have a previous nuclear bone scan to compare with. No big changes there.
So…my next bone density scan will be in September. Decisions to perhaps add another injection will depend on that or even some kind of change of meds….like Tamoxifen.
Arghhhh….
However since Exemestane is on my radar it helps to hear of your decision and experience. You are not the only one I have heard tolerated it better than one of the other inhibitors. Thanks for that.
Video filmed this week so coming soon
Thank you Liz this is so helpful. I stopped taking exemestane in July after taking for almost 9 years. My hot flushes have reduced so much and I have a general feeling of well being that I definitely didn’t have when I was taking it. However, now I worry about cancer coming back, my cancer was ER+ grade 3, stage 2. My GP contacted the oncologist to check with them that it was ok for me to come off and the message came back yes. Is there anyway I can get more insight into my PREDICT results or is it likely I might get an appointment with my oncologist, do you know?
Hi Doctor, I listened and I am on exemestane. I just started along with Lupron. I was not menopausal but put into menopause. I was looking for your video about exemestane. I didn’t know it’s steroidal. I don’t want steroids, more so since I have to take for 10 years. What’s your opinion on it?
Thank you dr Liz! Do you recommend weight lifting (light weight) in the gym if I had axillary node dissection? I heard that it can increase the chance of lymphedema. Thank you
Outstanding information 🌺u explained it so much better then my oncologist 🌺
Glad it was helpful!
I wish you were or I knew of this when I approached my oncologist in 2020 when I was being proactive when I was told I have a long time to cross the bridge that's when I get there that my concern is I can't take anything that is not steroidal because of my lungs is there anything besides what you're putting forth in front of me anastrosol versus Lexapro and he said no there are no steroidal I how about that extreme one he knew what I meant and he said no that's not for yo,
I have to say it's a blessing that we have you and I wish I was able to write my story much clearer and my experience because I can't right well at all and I don't meanjust grammatically I'm just a horrible fragmented non-rama LOL but all my reports clearly states all these contradictions in my previous posts but you are a blessing for women and I thank you for that
This is excellent a video I now am aware of the side effects
I am concerned I have hormonal positive breast cancer and I am using Anastrozole ...my point?
What do I do to balance my hormones I am in menopause and 62 years old now
The cancer spread to my left hip and my lower back.. please help me !!!!!
I brought a treadmill, which is great when its to wet or cold to get out ,highly recommended
So did I and it really is a blessing. Start Letrozole after seeing my surgeon this week for BC and my husband has Pulmonary Fibrosis after having Covid and we use our wonder machine every day. Doesn't have to be an expensive one (we're pensioners) ours cost £200 from Amazon.
Thank you fir your clear explanations.
After 10 years on Anastrozole then what? ( 8cm lobular tumor, 28/32 lymph nodes positive) afraid it will return if anastrozole stops) seeking advice!
How long you take Anastrozole?
So helpful as always. With high cholesterol with AIs do you recommend a statin?
A lot of people who has high cholesterol recommend not to take statin because it is toxic for your body.
I am on Letrozole but about to add ribociclib. It is designed to interfere with the cells’ growth cycles. I need an EKG and blood work baselines because of potential heart and other side effects from the drug. Adding another drug is really frightening.
I know to can be - but think of it another tool that can reduce the risk of your cancer coming back
Hi, Thank you for your amazing videos Dr O’Riordan. I take a 60ml cold pressed Immunity Support turmeric shot supplement from the Tumeric Co, containing Organic tumeric root, ginger root, vitamin C (1000mg) and D3 (3000iu) and am on Tamoxifen (for 2 years after a E positive breast cancer, a lumpectomy and radiotherapy). I had no idea the tumeric could interfere with the tamoxifen. Should I stop taking it? My lump was grade 2 I think. Also should I switch to Anastrozole now? I think I’m low risk of reoccurrence but I’m scared it might come back somewhere else. I’ve cut right back on alcohol, I exercise most days and am a healthy weight. I’m 57. Thank you so much. Ollie
Stop taking turmeric. You don’t need it n
I am interested about what you are talking doc I always watch and I learn also about breast cancer
Liz can you let me know if you should avoid grapefruit when taking anastrozole please?
Thank you ❤
Thankyou for making such informative videos. Pls guide me on below case. My mother is 71 years old and had undergone mastactomy last month. Post surgery on biopsy 2 tumors were identified. One of 1.2 cm invasive with ductal and lobular growth and second tumor of 2cm encapsulated pepellary carcinoma. All nodes are clear. On IHC both tumors are strong ER+ PR+ (8/8) and her 2 neu equivocal which is later negative in Fish test. She is on insulin as diabetic and hypertention. Pls guide now what further treatment she would require. Thanks in anticaption of the same
How do I know if I am still peri menopausal or in the full blown menopause? 3 years ago I had a mirena coil for heavy periods and started HRT then developed hormone hungry stage 2 breast cancer so had to stop the HRT and remove the coil. I have watched your videos and I have been advised to have radiotherapy and hormone treatment for 5 years but how do I know I’m on the right drug?
I am on ovarian suppression and anastrazole for stage 2 premenopausal breast cancer. My estradiol level is 19. Is that normal? I thought it was supposed to be less than 5?
I was diagnosed with sever carpel tunnel in both wrists prior to my breast cancer diagnosis. I have had 2 rounds of steroid injections to manage the pain. I had my lumpectomy last year and then finished my radiation treatment in November. I am currently on Letrozole for the next 5 years - although it causes sever nausea so I only take it 3x a week currently. My oncologist wants me to gradually increase this if I am able. My question is, does Letrozole make my carpel tunnel worse? I have read that Letrozole can cause carpel tunnel but I have not found anything about managing both carpel tunnel and breast cancer. Thank you!
I had 2.3cm her2+ive bc... treatment was 6 rounds of TCH, surgery plus one lymph node which was clear, the cancer had reduced to 1.3cm at time of surgery! Then 19 radiation treatments and the 14 rounds of Kadcyla and now at the 10th round (its awful stuff too) ....
There was a trace of er positive and the oncologist has me listed to start letrozol soon after the targeted chemo, my body is struggling with pain all and need a break from treatment as 18 months is hard on body!
My question for you, if I have only a trace of oestrogen does this warrant a AI?!?!
I am 57, had a hysterectomy at 50 and now post menopause.... what are you thoughts please? 4:09 ! 4:57
At minute 5 you say you had a recurrence with Tamoxifen. My oncologist recommends it to me. How high in percentage is the benefit of taking Tamoxifen? Do those calculators predict or adjuvant online give answers to this question?
Just started Letrozol, if it gets bad I'll quit
Can you please address the use of vaginal estrogen for dryness? I have been on it for years, long before my BC diagnosis due to post menopausal dryness (I'm 63). Moisturizers did very little. I'm stage 1 (invasive dcis with 4-6 mm), grade 1. I was diagnosed in the beginning of 2023 and had a lumpectomy, radiation, and Letrozole. Im still using vaginal estrogen (vagifem) because i don’t know what else to do. I had a bad case of vaginal atrophy long before getting BC. I'm scared!
BC is scary. I also experience PMD. My gynecologist prescribed VE for dryness & irritation a few weeks before my BC diagnosis. A wee internal voice told me to delay starting the VE. Once my biopsies came back ER+ I called the gynecologist to ask if starting VE was a good idea. She told me not to use it. Everyone is different. Please check in with the doctor who prescribed VE and your oncologist to help make the best choice for you. Well wishes on your journey.
@muniratjunaid8887 thank you! Best wishes to you, too. I tried the Mona Lisa laser last February and it has made a HUGE difference - better than thd estrogen I was taking. I'm off estrogen now.
What if one is already disabled? Weight bearing exercise is not possible for all.
How responsive is high ki67 to hormonal therapy and to chemo therapy?
Very
This so helpful and explained well , i got her2 positive breast cancer grade 1 ,i have had a mastectomy and my oncologist put me on Anastrozole, but have been suffering from real bad bone pain and Neuropathy in my hands and wrist, so he told me to stop taking Anastrozole and has put me on exemestane ,i looked into this and its a steroid , i really dont like taking steroids as they cause extreme weight gain ,so im worried about taking them ,im still suffering from bone pain and have been of Anastrozole for nearly 3 months, would i be better just going back onto them ? Not sure if i can risk the other medication
Thank you