TWiV 1150: Clinical update with Dr. Daniel Griffin
Вставка
- Опубліковано 20 вер 2024
- In his weekly clinical update, Dr. Griffin dives into West Nile virus in New Jersey, poliovirus vaccination campaign in Gaza and Afghanistan, California dengue virus infections, children dying from flu, mpox vaccination procurement and antiviral usage, flu circulation in US, before reviewing the recent statistics on SARS-CoV-2 infection, finding a new wasterwater dashboard, if the monovalent XBB.1.5 COVID-19 vaccine is effective against circulating SARS-CoV-2 isolates, the need for nasal mucosal IgA in response to SARS-CoV-2 infection, where to find PEMGARDA, does administration of molnupiravir reduce symptoms in the vaccinated, when to use convalescent plasma, how molnupiravir treatment leads to better outcomes 3 and 6 months after treatment, a reminder of how and when to use steroids to treat COVID-19, what do when healthcare workers succumb to SARS-CoV-2 infection, if vaccination against SARS-CoV-2 does protect against long COVID, and if those taking the anti-diabetic drug metformin have higher or lower incidences of long COVID.
Show notes at www.microbe.tv...
Become a patron of TWiV at microbe.tv/con...
----------- CONNECT -----------
🎯 Subscribe! bit.ly/2HOYdNP
Instagram: @profvrr and @microbe.tv
Twitter: @profvrr
TikTok: / microbe.tv
Facebook: / thisweekinvirology
Our Podcasts: microbe.tv
Contribute: www.microbe.tv...
----------- MORE VIROLOGY -----------
•My Virology Course virology.ws/co...
•Virology Blog: www.virology.ws
•Virus Watch bit.ly/3ngvQIM
•Principles of Virology textbook amzn.to/34onDtg
----------- OUR SCIENCE PODCASTS -----------
•This Week in Virology bit.ly/30uUhrX
This Week in Parasitism bit.ly/3ndUNUZ
•This Week in Microbiology bit.ly/33tOUeO
•Urban Agriculture microbe.tv/urbanag
•This Week in Evolution bit.ly/3ne1bf5
•Immune bit.ly/2HOyCVb
•This Week in Neuroscience bit.ly/2So12Yd
•Infectious Disease Puscast bit.ly/3K4EKF0
- Who Am I? -
I’m Vincent Racaniello, Earth’s Virology Professor, and I believe that education should be free.
I’m also a professor of virology at Columbia University in New York. I’ve been doing research on viruses since 1976, and teaching virology in classrooms and online since 1999. On this UA-cam channel I share videos of my lectures, podcasts, and more.
New videos are uploaded several times each week.
I do not run ads on our work as it is disruptive to learning. We depend on your support.
If you would like to support our work, go to www.microbe.tv...
MicrobeTV appreciates your donation and your support of our mission. Our budget and ongoing financial health rely on accounting for and accepting irrevocable, non-refundable donations from the public. Therefore, MicrobeTV considers all donations to be nonrefundable.
Content in this video should not be construed as medical advice.
-----------------------
#microbe #viruses #coronavirus #pandemic
-----------------------
You guys are among the most generous people in the world, it's a pleasure to be here
@@DudeFun-yi7nu I love the use of the word generous. Reminded me of what this really is. I don’t want to take this for granted.
I’ve been watching this show for a while now, and the both of you are doing a brilliant job.
Please don't ever stop doing this - it really matters!
Many, many thanks for sharing your knowledge with us! The viewer questions/answers were especially great this week.
Thank you thank you. I always listen closely and try to learn!❤️❤️❤️
Thank you both again for all the effort you obviously make to produce these weekly episodes. They are GREAT! Do you have updated information on the relative effectiveness of the Novavax, Moderna and Pfizer boosters? Best Wishes, William Bailey
Thank you for sharing your time, effort and expertise. 🎉
But great show, thanks for all you both do!
Thank you.
That's excellent .Thank you very much guys.
FYI I'm 83 now. I have had flu vaccines every year in late September or early October every single year as long as it has been offered by my HMO. I have diabetes and asthma, high blood pressure and my age is a factor. This is a sample of one, but I do not get influenza. I go shopping every week at a busy grocery store and go to my local farmer's market that is quite busy Spring through Autumn. My family visits and my caregiver moves from home to home six days a week and has exposed me to covid which I did not get because I am throughly vaccinated for that too. I live in a huge complex of apartments and density for over a mile all around is very high so opportunities for infection are high too. When influenza has raged through our apartment complex I have not been infected. I am an advocate for vaccinations, not only because it works for me, but also because it will work for you. These days I mask at the grocery, but not at the outdoor farmer's market. I wash hands fairly often but not incessantly. I also keep current with all other vaccines. Why can't others be as diligent?
Asymptomatic
Great information yet again. Thank you both
Thank you for another informative video.
Looking really tired and losing weight rapidly. Raspy voice. Hope all well.
I don’t know if I have this just right, but it’s close: Perturbations in motion of Uranus (FACT) didn’t fit the theories developed at the time (Newton and, I think, Kepler). The laws (THEORIES) certainly weren’t thrown away. The fact was shelved until an explanation for it could be found.
Eventually, the fact was integrated into the theories with the discovery of Neptune.
So, let’s not be too simplistic. Naturalistic inquiry advances with good logic, open minds, and willingness to be puzzled by the apparently simple or obvious. 😍
Please give us the current symptoms for Covid 19. I have had a cold that stays in my nasal passages for almost four weeks. Sometimes have a fever. What does Covid19 present as symptoms and am I still able to transmit the viral infection I have.? Thank you .
Unlikely to be COVID-19. Perhaps you should get a LFT.
@@christopherrobinson7541 what is LFT?
It's all COVID related. COVID is so rampant and constantly mutating we'll probably never have a mild common cold like we did before 2019
Health is a quadrillion dollar industry
What happened to the TWiV audio quality lately? Why are episodes so super quiet? This is, after all, an audio format (at least that's how it started and how I still consume it), so please go back to the former good quality we had been used to. Much appreciated.
Maybe intradermic way of vaccination increase more IgA secretory antibody ?
Maybe If ,,cold agglutinine,, occur ,warmed oxigen (warming water in barbotor)can prevent erytocite aggregation at lung capillary level ?
Like all the facts that were censored away and kept from people during the pandemic. Thanks to freedom of information the truths are coming out slowly.
_"Like all the facts that were censored away"_
Which facts?
You obsessed over "facts" taken out of context. Had little experience in any experimental data. Made up theories and used FOI to push a pov and platform unproven points.
Dr Racaniello is poorly informed about epidemiological topics so it is disappointing to see Dr Griffin yielding every time to Dr R's opinions. Like the one about T-cells even though all available research shows that vax protection wanes after 4-6 months. It is strange to see a presumed scientist so dogmatic in his thinking. If you want to get better insights on epidemiology of COVID etc you would be better served listening Dr Osterholm's podcast.
Why are you here then? Stop trolling, if you have another expert with another opinion why not talk directly to the host, that would be proper IMO!
Michael Osterholm is (very) poorly informed about virological topics and does not appear to know the difference between antibodies, which fade quickly, and cellular immunity, which doesn't. The influence he had in the early days of the pandemic was unfortunate.
_"Like the one about T-cells even though all available research shows that vax protection wanes after 4-6 months."_
The protection afforded by antibodies falls as the immune response contracts. These antibodies target specific regions on the spike protein (epitopes) that move as the virus mutates. This allows the virus to avoid immunity acquired from from the vaccines and previous infection. The cellular immunity (T cells) target different epitopes on the spike protein, that do not change much between variant subtypes, so it remain effective.
The upshot is that as the antibodies fall the ability of the vaccine to protect against mild disease fall, but the protection against serious disease and death, is maintained at a high level.
The 7 dead high-school football players. That's what doesn't fit. That's when discerning people throw away your theories.
That is the way young people die. The rates of MADS now as it was before the pandemic.
Ah an anti vaxxer. Then what was the death rate of highschool football players otherwise. What is the death rate of the disease itself. Your number is pretty useless. Recently, in the US, the percentage of deaths in Kentucky was 4-6% due to COVID of all deaths in the state.
0:37 I'm sorry to hear Dr. Griffin has Ebola, again!!
To misquote Oscar Wilde To have Ebola is unfortunate to have it twice is carelessness.
He's referring to his bow tie!