Understanding Aripiprazole: Uses, Side Effects, and More with Dr. Syl
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- Опубліковано 28 вер 2024
- Join Dr. Syl, a junior doctor in psychiatry, as he delves into the fascinating world of Abilify, the brand name for aripiprazole. This medication is widely used in psychiatry for conditions like schizophrenia, bipolar disorder, and depression. Learn how Abilify works, its benefits, potential side effects, and the science behind its use. Whether you're a medical student, a patient, or just curious about mental health treatments, this video provides valuable insights into one of the most commonly prescribed antipsychotics. Don't forget to subscribe for more in-depth mental health education content!
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Timestamps
00:00 - Introduction
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Remember me? I am the guy that used to get first a lot!
My relative who has bipolar takes aripiprazole regularly. She gained weight and striaes. And I'm worried about her blood sugar levels as well as her kidney function. What do you think, Doctor..? She also exercises 1-2 a week but overall I'm really worried about her health 😢
This is the medication I'm on
Abilify sent me maniac and hospitalized for a week.
Me too
is there a way to vomit or take it out of the body?
@@ItaloT-gu2rpthese drug caused me permanent damages
Tried it for my (horrifically) treatment resistant depression. The only thing it did was make me want to eat ALL the carbs. This kicked my purging disorder into gear again and I finally told the doc managing my meds I needed off it. Ugh, it was awful
as an Aussie MH nurse I find your videos incredibly informative and helpful for clinical practice. Keep up the great work Doctor Syl!
I have noticed a marked improvement in negative and cognitive symptoms. I did not notice how impaired I was until I was on this drug for a couple weeks.
My psychosis was as bad as any case, and aripiprozale helped me to overcome my voice hearing. Total life saver!
Unfortunately antipsychotics actually have worse longterm outcomes than taking no medication
@ganglestank If I didn't take my meds my life would be insufferable... so I take them. It's been four years now and I don't get any side effects.
U probably low in b vitamins and magnesium
Hi sir
My kid is 8 years old, he is on 1.5mg risporidone, is there anything else helps him. Kindly reply
This drug cause me permanent damages and destroyed my life and many others.
My psychosis was better than drug induced hell
A nightmare medicine. Just hearing the name gives me chills
Got prescribed this one because it makes people extroverted. Spent the whole day vomiting. Also had a good laugh at the notice listing "sudden inexplicable death" as a side effect.
SECOND!!!!! LETS GO, DR. SYL HONOR THIS PLEASE. THIS TOOK DEDICATION AND TIME!!!!! YAYYAYAYAYAYAYA
Interesting video - i was put on Abilify as my first anti psychotic medicine and it made me into a zombie, it was horrible to be on.. I guess i responded really bad to it then haha!
It took them 2 years of all medicine not working before they gave up, it took 3 years before someone asked if i was correctly diagnosed 😑
Interesting it can be used for depression and aggressive autistic people!
I did get my diagnosis changed to Autism actually - I DID have small psychotic episodes, but i think we agreed that they where major anxiety symptoms compressed by stress and eventually blowing out of proportions..
I have heard from friends who does need anti psychotics that it works really well for them though!
I find medicine very interesting though!
A good friend of mine is autistic and has been a doctor for 20+ years. Every autistic person is different (obviously), but autism doesn't have to stop people from striving for their dreams.
Im on abilify. Its very effective against my schizophrenia and I’m happy with it. I love this video. It made me feel even better. I saw a thumbnail of a scary video on UA-cam saying “abilify causes chemical lobotomy” I don’t feel that myself. I only feel it keeps me in check. So I don’t get so emotional that I break down and get psychosis. For example my grandmother is on her death bed and I am very sad that I have to say goodbye to her beacouse she is very close to my heart. But I feel I have the sadness under control which I did not when my other grand mother (on my dad’s side) passed away. Then I broke down completely and ended in psychosis. At that time I had quit the mediciation in secret. I was on another antipsychotic before.
But abilify makes me feel so good, it takes away my depression and I have not got oculogyric crisis with it. I have got that with another. It was very distressing and horrible for me.
I like abilify a lot and what it has done and is doing for me. Bless Arvid Karlsson.
Thank you for this video!!
That "abilify causes chemical lobotomy" video really scared me. I have the same results from abilify that you described. They gave me abilify and risperidone and it's the best and most functional I've ever been, when I manage to take them.
Each person responds differently to antipsychotic drug. Side effect is real. Add more meds to cover that ? What if the patient refused the med, any alternative ways and support?
I'm so lucky I only experienced Akathesia once (titrating up on Ami). It is absolutely relentless. Couldn't sit for more than a minute without my own body (independent of my mind) compelling me to move. It's honestly torture.
Could you maybe make a video on the use of Mdma in therapy for depression or ptsd? I found out that the research has come as far so that its now a treatment in Australia. What are your thoughts and/or where do you stand on the matter?😊
Abilify caused akathisia for me and I was moved to Latuda. Latuda definitely works a lot better for me
Love these medication videos, please make more
This is fantastic, thanks Dr Syl.
Would you be able to do similar videos for other common medications?
I see you've done some, I'm on desvenlafaxine and would love to hear your take on it
I was given this to help with sleep at one point I think 🤔 I like learning about dopamine receptors. What triggers the dopamine increase and can dopamine be decreased in the long term?
A family member is on Abilify and it has worked wonders almost back to 100%. My family member had tried Risperidone and Paliperidone which were both ineffective.
I tried it along with lamotrigine and bupropion, and it was the worst in the world, the first days felt like a very bad flu, then when I increased the dose it induced " Pure O OCD", horrible thoughts and images about torture and pain, they tormented me a lot.
What about ADHD? Its been used off label there too to help regulate dopamine
Really? Most ADHD meds are designed to increase Dopamine, not block or reduce it.
Thanks doc! Do one on cariprazine.
I had a bad acute dystonic reaction on Abilify and akathisia so it was not for me, but I can see it being a great choice for many.
Bad drug!
just started taking this 2 days ago! wish me luck lol
Update???
update
@@amn_ham9678 guess he died
@@xgengx7530 @amn_ham9678 it has been the best medication I have ever taken. Especially for anger. I feel amazing
But I do have a pretty increased appetite. I think gaining a few pounds is worth it tho
So weird case here. High functioning autism, on set of psychosis same time a year after 6 months of cannabis use. Second episode caused life threatening catatonia.
Symptoms were similar to those with Lewy body disease. Similar to low dopamine disorder.
So my question is do we know why individuals with low dopamine have same symptoms as Individuals with psychosis who have high dopamine?
They gave him Abilify as a way to balance his dopamine since they had no clue why he had symptoms of low dopamine while having psychosis.
Good question… wonder if Syl will answer it.
For me it was really helpful at reducing the compulsions ive had for 20 years
Aaaaaat the tradeoff that it made me eat uncontrollably
Overall i decided the skin picking was preferable to wanting to eat all the time
I wonder if that could have settled down after time if i kept up with it because nothing else has helped nearly so much
Is it useful in bpd? I take high doses of seroquil but have experienced weight gain and cholesterol issues
Can they make me take abilify? Is that legal?
I answered this question in an upcoming video.
ameprazole is one of my meds, is this like what youre talking about...
DrSyl….Have you had experience with Nabilone+Duloxetine tx for (severe) neuropathic pain, C.P.T.S.D+N.E.S+nausea.Thoughts?Suggestions? Ie.medications breaks, brain zaps, etc.*We very much enjoy your info sessions/podcasts.
I have a problem with walking round in circles and shaking
Could you do a video on Paliperidone 1 monthly depot, 3 monthly and bi annual-thanks
Yes this!
Im on 400mg once a month depo
Horrible akathesia
abilify is still sedating for me so i take it at night😅
this didnt work at 30mg for me and all the other antipsychotics are terrifying, ill probably stick to something less harmful like lsd
Weak sister to the evil litany of the rest of this evil class of meds!.Antiquated , Over used. Time for something not 40yrs old.
Why isent eny gay Schizophrenia
you're making videos about a field of pseudo-science even it's accepted as scientific. i can't blame you since you're educated by this sick system but it doesn't change the fact that you're doing a really bad thing for ordinary people.
Go to work on medical 😷 😂😂🤔😭😅😜🤞🤞🤞
Is such side effect common? Or was the prescription just wrong? 🫠
Abilify didn't work for me. I was 12 and apathetic. After a few months I quit the medication on my own coz I was scared with being unemotional and depersonalized.
Only at the age of 24 I was diagnosed with "15-years-lasting" clinical depression and began treatment with sertraline. Never felt better.
i wonder what would my life be if this depression was treated earlier...
Aripiprazole was an awful medication for me. Was not strong enough even on the highest dose to help me when I was in full blown psychosis, but it made me feel terrible as well. I became like a zombie and lost interest in every thing. I would sit and stare at a wall non-stop for 12 hours a day apart from to eat or go to the toilet, because nothing interested me and I couldn’t bring myself to do anything. At the same time, my legs were restless, so if I wasn’t jiggling my legs on the spot, I was pacing for hours every day.
happening rn damn
Sad wery terrible
This is worst than holycost
Apparently it dulls down dopamine, one reason why some people stunningly went from never gambling to gambling….( Needed “reward”.). You describe a dopamine blocking effect, though of course it’s far more complicated than that… which is one partly truthful reason the R&D ppl, manufacturers, and doctors will say “don’t know exactly how it works.” This med is prescribed for ANYTHING and everything, but note most of all perhaps it’s use in turning down so-called “aggression” in suffering 6 to 10 year old kids. It’s a variety of “throwing wet spaghetti against the wall.” Not necessarily evil, but wandering round in the dark. Not always (the profession and drug manufacturers) so honest (certainly not transparent or interested in longterm use effects… studied for 6 weeks, not 6 years or 6 decades) … I’ll maybe finish this but I’m writing this at minute 5-7.
Horrible drug. I’ve been off for a year and a half and am still not ok.
Could you do a video on diet With medication news to see is it any research to support the diet could play a big part in Psychosis in illnesses so the closest player part
Dr Syl. Would love to hear your thoughts on mental health of Clinicans, as we work with such vulnerable people and we can be exposed to client deaths. Wondering if you know about this and how it impacts and how you feel Australia’s health care system is supporting this side of mental health
Please do Respiridone 🙏
I was prescribed this medication for bipolar. It was perfect for me mentally, but not physically so I had to change meds. It made really relaxed and chill so it was good for my anxiety, but it made me too chill. It made me overly sleepy all the time. I’d have to practically overdose on caffeine just to have the energy to stay awake on these meds
Sam
You're explanations are the best I've ever had I have to say !
And you are very attractive 😊
Can you please explain the drug Lamotrigine for BPD mood stabilisation please Dr Syl? :)
I got Tardive Tourettism from Abilify. I've had it for 5 years, got off Abilify years ago and this appears to be permanent and severe at times.
Also, I gained 70 pounds on abilify and I only lost it when I switched.
These drugs cause DISASTERS
What was your dose?
@@xgengx7530 I was at the 400mg injection for years and then the 300mg injection
I got so lucky that I responded so well with risperidone, now I'm down to a .5mg daily dose. But, it has been such a life saver, the auditory hallucinations are unintelligible, and although the visual hallucinations are still startling they aren't terrifying, and both quickly fade
People get angry it is normal to medicate a autistic person because they are overestimated is wrong there are other ways to reduce the sensory overload than dosing them with antipsychotics which can have very unpleasant side effects depending on the amount given. Doctors and CPN's need to work towards having a therapeutic relationship with their patients this means hearing them their needs and being prepared to compromise. Also as far as possible resolve issues.
Which is a more safest antipsychotic for schizophrenia in diabetic patient in between Lurasidone or Aripiprazole?
Very informative video! I read about a new medication for the treatment of schizophrenia spectrum disorders (possibly other disorders aswell); I don’t remember the medication class, but from what I heard they are revolutionary. Also, would you be willing to make an in-depth video about the hypothesis’s of various mental disorders (depression - noradrenaline and serotonin, schizophrenia - glutamate, dopamine, etc). I’m taking pharmacology soon and would find that type of video informative.
I’m sure other people would also find it incredibly useful and informative. I think a video on how you use your medical knowledge objectively, without being biased would also be a cool video.
Awesome video as always! Could you make videos about quetiapine and lithium?
I have diabetes because of it. I was suffering from anxiety. I also do have thyroid issues that happened after this. Before this video I had no idea this could happen. Of course the doctor never mentioned that. My life has been ruined of all these meds since i was 12. This was when I was going through puperty that should have been looked at instead. I am a trans guy and I have not been depressed since hormone treatments. I also had a hysterectomy now it is not possible to ever get my cycle anymore because that screwed things up for me.
Aripiprazole 5mg can be used during pregnancy?
I had a horrific and pretty unusual reaction to aripiprazole for treatment-resistant depression. It made me incredibly drowsy and sedated, but I could not actually fall sleep. I spent whole days and nights laying in bed, constantly about to drop off to sleep, but every time I did, I jerked back awake with that sudden sensation of having fallen. Over and over again. I also had akathisia. It was torture and I could barely function or think. I only managed micro-sleeps and very light sleep for several days before I refused to take it any more.
Never been prescribed it before, but that sensation of falling jerking back awake happens to me from time to time. When it does happen it's irritating. Usually when I've been staying up too long.
This sounds like me in two episodes of major anxiety.are you surf it was the medicine?
@@w.okkerse915 yes, it went away as soon as I stopped taking it.
this happened to me but on wellbutrin too so its definitely some mechanism of dopamine that they dont fully understand
My severe allergic reaction: about 12 years ago I was prescribed Abilify (unfortunately, I don’t recall the dosage) by my Psychiatrist as an adjunct to 300 mg Effexor XR treating chronic MDD with minor anxiety.
After only 2 doses, I was in the ER with severe allergic symptoms - I felt like my throat was closing over. In addition, I had a puffy-swollen face (eyes watering) with red/splotchy & itchy neck and upper chest.
I was given some medication (sorry, I don’t recall what it was… perhaps Epinephrine) and immediately discontinued Abilify and within 24 hours felt fine. The ER Dr. also reviewed what else may have caused the reaction such as ingestion of new/unknown foods, environmental changes, etc.
I have Abilify flagged as an allergy on my pharmacy profile to be safe. Also, it is noted on my GP profile as I no longer have a psychiatrist.
Edit: typo
Would be fun to hear more about vortioxetine/trintellix. It has such a weird activity, it's kinda unique, and it helps some people who have GAD and some don't get effects for GAD
It’s an interesting one. Meta analysis showed it’s basically worse than even buspar in terms of effect size on anxiety. Yet, like buspar, some do find immense GAD relief!
For me, it was like a slightly less extreme Prozac / Fluoxetine. Very activating and any energy automatically turned into worsened anxiety, nervous tension, stress and irritability. It never ended up helping me.
Aripiprazole 5mg puts your emotions on a leach. It limits their extent, but don't eliminate them. But I stopped them after feeling that my emotions were somewhat annoyingly restricted; especially in terms of experiencing positive emotions.
Clark Maria Wilson Cynthia Jones Susan
I would love to see you dona video on dopamine partial agonists as adjuncts for depression
I feel no inner peace anymore, no feelings at all, when I take a full deep breath, I feel nothing...
Are/were you on Abilify?
@@TAG-1984 Yes I'm on abilify and zoloft
Very interesting. Abilify for aggressive autism! Low dose would be the aim, due to these medications cause movement disorders (making life more stressful)
You'd posibly enjoy Josef's channel, (the taper dr.) He's actually been on an antidepressant himself and has uploads on his withdrawal. He's an aussie shrink who used to work for FDA, but perhaps works from canada!
😊thanks for the upload
Yay! A fellow Dr. Josef supporter. Also I want to see definitive non bias studies proving Abilify works for aggressive autism and that its benefits outweigh the risks. I am not convinced this viable. I totally need to see the data. Also Josef is USA based.
@kassi4837 brilliant! He has some amazing advice, due to personal benzo withdrawal experiences.. Syl and Josep are my faves. I work in the disability field and my youngest 2 adult children have Tourette's 26 &28 y.o now...
Four years ago, a doctor overdosed me on maxalon & it gave me tardive dyskinesia & dystonia..
It gave me my children's illness/syndrome.. My gp didn't believe my symptoms at 1st! Awful!
When I first asked the neurologist, Weather TD and dystonia is the same thing as drug induced tourettes syndrome, he said "yes, more or less"
At 1st, I was too afraid to let him know that I had been admisted maxalon during my last 2 of four pregnancies 🤔
That's how I ended up here🤣 Because ME & the medical profession, needs to catch up on side effects aka the possibility of movement disorders from anti-nausea and ssri medications
i actually get this super rare side effect of eye-spasms (i can't stop rolling my eyeballs upwards)
otherwise i feel this is one of the better meds when it comes to drowzyness. oh well - quetiapine it is for me, i suppose
I have seen these eye spasms happen to someone before. Looks extremely uncomfortable. Sounds like you have to be super careful when managing meds to avoid/ manage this.
@@kassi4837 it's mostly annoying especially if you really need your eyes (for example, you visit a friend with your car, then get these spasms - and they last for a few hours and then it gets to evening and you want/need to go home) - it's mostly a huge inconvinience
@@N3Selina I am sorry to hear this.
@@kassi4837 i appreciate the kindness - quetiapine works well for me (most of the time) so i am not comepletely without medication
For the "people with autism," the preferred term is "autistic people." The reason for this is that saying "people with autism" pathologizes the autistic neurotype.
So "schizophrenic" or "person with schizophrenia"? Which is correct now?
@@monte68x I love the idea of some countries to get rid of the term schizophrenia as it is more of a buzzword then everything else. Maybe its chronic maybe its degenerative, that might be valid, but stigma makes things worse. I would create a hashtag out of it#psychosisNotSchizophrenia, maybe?
Dear Doc , my 15 year old nephew took them for 14 days he’s doing great , has addiction to games and phone Omg ! But when the doctor said he has shown tremendous progress but should still take it for another 14 days it broke my heart and I’ll fully against this ! My sister is insisting but I’m against it , please say something
Thank you Dr Syl for this informative video. I have been on Aripiprazole for almost four years now, and my dosage has been decreased (by increments of 5 mg) from 30 mg to 15 mg over a long period of time. I feel a whole lot better, now that my dose has been significantly decreased. You say that weight gain is not a common side effect, but I have experienced a weight gain of over 14 pounds, which has significantly affected my body shape. And yet, when I was on Risperidone for some years, I gained not an ounce. I guess, different strokes for different folks. I also feel considerably less sedated, now that I am on a lower dose. You describe this drug's use for Schizophrenia, but may I respectfully point out that Schizophrenia is somewhat different from Schizoaffective Disorder (which I have been diagnosed with, and treated for). My own psychiatrist highlighted the differences to me, when I described myself as 'Schizophrenic'.
On 10mg ive sufferred Akesthesia. And with fibromyalgia ive been in so much pain. Ive had to reduce to 5mg and its less acute but now on propanalol to counter the Akethesia. Ive never felt so good as on 10mg mentally. 5mg im less stable but glad im on it. Will see how the weight gain goes but less appitite than respiradone on which i never felt full. Thank you for this video. From UK
Abilify is being used now to treat ME/CFS (what I have) with great success in some cases. Which I find fascinating considering ME is an autoimmune disease and comes usually with POTS as well. I wish more doctors would talk about this condition because right now very few ones are 🙏🏻
8:10 wow I’ve never had these tests / measurements performed before starting an AP or while taking it, maybe because I’m a skinny guy?
Either way this med seemed to work for my bipolar depression at first but then stopped. As the dose was increased I got akithisia so I eventually had to switch to Latuda
Great vid !
I'm wondering if the metabolic workup is still generally recommended if Aripiprozole is being used at the 2 mg dose for SSRI augmentation?
I was the first real human to respond!
🔳 Check the box to verify you are human.
@@Maverick_Mad_Moiselle DONE!
Yeah my daughter is on max dose Aripiprazole and max dose olanzapine to maintain stability. Theyve tried to reduce it but nope she totally needs both
Abilify is the bomb 💣 schizoaffective here
How much caustic soda is in Abilify Maintena?
Can you do a video on lurasidone? Love these educational videos!
Is ablify useful in dp/dr
Depot are horrible never take one
Thank you for the informative video! Abilify was really helpful for my intrusive thoughts. could you please do a video on lamotrigine and how it works for borderline personality disorder?
I was on Lamotrigine alongside antidepressants (Venlafaxine and then Zoloft) for a few months and it no effect at all on my anxiety, depression, OCD, or my BPD.
I've used alcohol at one point where i had prescribed aripiprazole and i had anterograde amnesia episodes for 3-4 days, which repeated after 20 or so days for a few times
I've been taken to hospital and had an EEG which detected no anomalies so i don't know what to think about this whole ordeal
Do one on CLOZAPINE
Done already!
Benzos are best
benzo's are the most damaging drug out there, they cause severe addiction and withdrawal, worse they are the only thing that treat akathesia, but they also cause akathesia so if you get it while on them, you are officially screwed.
Props to all who no longer desire to resign their own personal power & are transitioning off this demonic crap 💪
Amen
I was a doctor before I retired, worked in different fields including psychiatry and as a GO in the end.. Ability is the ultimate Zombie drug.
It's Abilify. Not Ability..
I tried Abilify and loved it! I was a super responder, even wrote an ode to the medication. lol I was on it for a year before I decided to switch to Latuda due to weight gain (15.8 kg).
It was so great that you had to switch to a different med? Makes sense.
@@monte68x"due to weight gain" side effects sometimes outweigh the benefits of a medication
Edit: I honestly didn't mean that pun, I'm so sorry..
Bot 😂
I'm on it for bipolar disorder. It's worked wonders for me. I haven't had a manic episode in forever. And i have zero side effects.
Bot
Helpful advice from the category of the classic "useful idiot." No offense meant. I've been there and done that and bought the T-shirt myself. Nasty habit. As if religion were the only "opiate of the masses. In any event, I'm looking to engage in a low dose, intermittent protocol, preferrably free from the constant, intrusive and harassing abuses of the authoritarianists whose advice per the norm of the professional world, is quite often worse than worthless. no offense. been there myself... ever heard of the concept of a "moral injury." yeah. I still carry that pain.
Im on olanzapine 20 mgs and i was going to switch to abilify when my dose of olanzapine got lower. Now they want me to stay on it instead of switching to abilify. Im having so much sedation with olanzapine and i heard that abilify is less sedating. Is that true? I gained 50 lbs on olanzapine in 1 yr.. When i was lowering it i lost 80 pounds. A few months ago i stopped all 0f my meds and i ended up in the hospital so im glad you put in there to talk to your dr before making changes. Haldol and thorazine made me have restless legs really bad.
Arirpiprazole gave me akathesia so I had to change to brexpiprazole. That worked so much better for me