@@abimbolaaku2709 nothing wrong in being at supraphysiological levels if u know what ur doing . individual choices should not be questioned . to each their own.
This video offered my 7 minutes of peace. It cleaned the mess i created, by every word you say things get more and more in place in my mind. Magical really
I normally struggle with understanding chemistry, but you explained it in a way that was straightforward, but still easy to comprehend. I very much enjoyed this video.
Unfortunately this comment is potentially antiscience and possibly antivax so I had to report it... Remember, never study the chemistry, scientist did it for you and can't be bothered explaining it to a poor test subject, go shopping and get triple boosted, it's absolutely scientifically proven 😂
You are so skillful in the way you explain things. We learn not only what you share but we learn about ourselves. We learn that many of us who maybe thought we never had a scientific mind, were just never paired with the right teachers.
I was about to watch a video of Dr.Mike’s just for entertainment, then I said “ I should really do my homework and look up NAD+” … well, this man does everything.
Drake brother , do you know before I used produce energy from dietary fats but after some months daily consumption of fats now I get dizzy for hours, do you think it's nad n fadh difficency?
Thank you. This is the first time I ever understood completely what NAD+ does. You went in perfect detail and answered questions I have been having for weeks. I am incredibly grateful you made this video.
I gotta say Doc, I haven't been this excited from a video presentation explaining biological chemistry in many many sun's! You certainly have a knack for not only educating the common layman, but also for invigorating that passion to understand our own biochemistry. Thank you for such a brilliant, enlightening, and motivating presentation. 👏
incredible video, the explanation in general helped me a lot but especially the transition from NAD+ to NADH+H+ and the final release of the electrons, thank you very much!!!
THANK YOU! I was struggling with the concept of NAD+ vs NADH but understood everything else in my materials. Thank you for breaking it down, you made it make sense!!!
I have an auto immune disease so my white blood cell count has been high for the past 13 years. It causes constant fatigue. I was just wondering if NAD helped you with fatigue?
Thank you so much. I was searching the internet for hours trying to figure out a good explanation for the electrons and determining where they come from. I could hug you right now. No one explains this well. Mostly because I think people don't understand themselves. :)
I’ve been getting off meds and even felt tired just walking. It’s been HELL. I just started taking NMN+ and I actually had energy to walk my dogs today and feel like I can run a mile! I’m not sure how long this will last but I’m taking advantage of it. I got a months worth and will keep taking it. Even if it only works today just having the energy is a godsend. And want to be clear it’s not a jittery kinda energy like coffee or any drug. It’s a very calm energy where I can sleep if I really wanted to or go out and not be dragging. It’s very nice to feel energetic again.
Thank you so much! I was watching a Biology video on Khan Academy and they just assumed we knew all about NAD+ forming NADH and then ATP, and 'explained' it in a very brief and hard to understand way! Thanks to you, I understood it crystal clear!
what have i been doing my whole life and where were you 2 years ago when i was in my 9th grade, one of the best lecture, helped me out a lot thank youuuuuuuuuuuuuuu
I am sitting here having an NAD infusion the doctor gave me, and trying to understand why NAD is going to give me this promised energy. You explained it perfectly, Dr. Mike.
@@teddybearroosevelt1847 oh lords no. I had a teacher who supposedly did his PhD but I didn't understand one bit. Not that I'm insulting anyone, I was just exaggerating cuz typically people with PhD don't tend to simplify what they explain to, say, someone like me who wouldn't understand complicated terms. tldr : i was exaggerating
Bro you literally explain way better than my university teacher LOL Thanks for it, I was really stuck in a Wrong idea about Nad+ (the part about the Nadh + H) and you really killed my doubt 🙏🙏
hi doc, im a spanish student and i was able to understand everything. your explanation was so neat and i undertood even more than in my native language. i don't know if you ever will read this, but could you do a video of NADP? i would really appreciate it a lot. greetings from chile
My basic understanding of creatine is that it also helps produce ATP. So, does it do this on it's own or is creatine kind of useless without NAD after a certain point?
It's amazing how some people are so people smart. Man, watching this guy's video is equivalent to watching 10 other UA-cam videos on the subject, if not more!
I get it, I get it, I get it.. I’m so happy. I’m reading a book called Mitochondrial Dysfunction and it’s so good, but I really needed to understand, glycolysis and kreb cycle to really understand what’s happening. I was not making sense to me.. after this video I’m mind blown and how wonderful the human body is.. OMG
4:17- The reaction is not balanced. The left should be added one more H⁺: NAD⁺ + 2e⁻ + 2H⁺ because two hydrogen atoms, 2H, are involved. But the right side appears correct if the H in NADH was a hydride (i.e. H⁻ , a proton and two electrons). If so, the left should be: NAD⁺ + H⁻ (2e⁻ + H⁺) + H⁺.
New to the channel, thank you for making each and every one of your videos, they are well done, very informative and break down the subject matter in a very understandable, efficient and productive manner, my classmates and I are very grateful for your hard work and continued inspiration, the effort you put into your craft is very much appreciated and has helped to not only meet but to exceed our expectations, please keep up the great work Dr.😁
So that means, NAD+ gives more energy to the mitochondria which helps the mitochondria to produce more energy to the cell which help the cells grow. Can i explain it this way?
Hi Doc, I've seen some research on NAD+/NADH and the potential anti-aging benefits... could you comment on that? and also would it make a difference in whether you take NAD+ or NADH supplements? I also read in some journals that the NAD+/NADH ratio changes as we age but I'm not sure if there is enough research to support that... your input would very much be appreciated!!!
It's very important. We die instantly without this process. As we age our NAD+ levels decrease making things difficult for our bodies to function the way they used to.
@@lucky2653 NAD is essentially an electron carrier that then creates a gradient across the inner membrane of the mitochondria. Which makes hydrogen go through a protein complex called “ATP synthase” and ATP is ultimately produced from this. It makes ADP fuse with another phosphate :)
This makes a lot of sense. If I am trying to take a supplement for energy, Does this mean I want to take NAD+ or NADH? From your demonstration here, it seems like the better supplement is NAD+
Another amazing video!! Really love watching your lectures simply because of how you break down the concept and make it much more easier to grasp. Thank you sir! :)
That was so well explained and I still didn't grasp it completely. I understand the outline and will have to watch again. But great simple explanation.
If only you were my teacher, I would have been more interested in chemistry. I did not have a Chem passionate professor till college, it ruined my high school life.
Perfect explanation 🎉 my chemistry teachers during my form 6 and lectures during my biochemistry class were ALL a great failure by NOT able to teach this pathway appropriately . Thank you Mike 😊
Sir, I have many doubt on this topic thank you so much❤ for clearing my doubt....you are such a great teaching skill... Once again thank you sir... Love from India ❤❤❤
I took 260 mg of nicotinamide adenine dinucleotide and it was no placebo. Increased energy, mood, and focus all day long. I’m going to proceed with caution until more research is done on its tumorigenic potential and impact on sirtuens, but damn. I’m not going to name the manufacturer in case someone thinks I have a vested interest, but this stuff works. Obviously consult your doctor before taking any supplements.
I've got a question, now ok we get 2 NADH + 2H+ in Glycolysis which needs 4 hydrogens. What about the Krebs cycle where we make 6 NADH + 6H+ and also the 2FADH2. Where do those hydrogens come from?
I came here for science but I think I need to hit the gym now.
Or buy smaller clothes like this dude.
We used to have Bro Science, but now we have Science Bros.
LOL, he really has that classic Australian Bondy Beach Body, doesn't he?
lol
doc showing his gains , vascularity and dropping knowledge bombs. cheers.
Steroids lmao
@@abimbolaaku2709 nothing wrong in being at supraphysiological levels if u know what ur doing . individual choices should not be questioned . to each their own.
@@vivinvincent692 I agree 100%. If I had a doctors guidance, I would take steroids. I’m already on trt. But I want other stuff to make the gains go📈
@@abimbolaaku2709 u should hire an expert . this stuff is not worth experimenting on.. has grave consequences..
@@vivinvincent692 that’s exactly what i said😂 “under the guidance of a doctor”
This video offered my 7 minutes of peace. It cleaned the mess i created, by every word you say things get more and more in place in my mind. Magical really
I normally struggle with understanding chemistry, but you explained it in a way that was straightforward, but still easy to comprehend. I very much enjoyed this video.
Unfortunately this comment is potentially antiscience and possibly antivax so I had to report it... Remember, never study the chemistry, scientist did it for you and can't be bothered explaining it to a poor test subject, go shopping and get triple boosted, it's absolutely scientifically proven 😂
same me
HOw did he make something so complex........seem so simple!?!? And his bicep gains is amazing! Well done Doc!
That is a gift!! Not everybody can simplify a complex subject so that anyone can understand! Fabulous
You are so skillful in the way you explain things. We learn not only what you share but we learn about ourselves. We learn that many of us who maybe thought we never had a scientific mind, were just never paired with the right teachers.
I was about to watch a video of Dr.Mike’s just for entertainment, then I said “ I should really do my homework and look up NAD+” … well, this man does everything.
Thank you. I finally understand what NAD+ does. I would give you more if I could. I'm incredibly grateful I found this video.
No problem
Drake brother , do you know before I used produce energy from dietary fats but after some months daily consumption of fats now I get dizzy for hours, do you think it's nad n fadh difficency?
Thank you. This is the first time I ever understood completely what NAD+ does. You went in perfect detail and answered questions I have been having for weeks. I am incredibly grateful you made this video.
You don't know how much I appreciate this video. Thank you!
Oh my goodness you are the only person I have ever seen to explain exactly how NAD steals hydrogens from glucose! Thank you!!
I gotta say Doc, I haven't been this excited from a video presentation explaining biological chemistry in many many sun's!
You certainly have a knack for not only educating the common layman, but also for invigorating that passion to understand our own biochemistry.
Thank you for such a brilliant, enlightening, and motivating presentation. 👏
You sir...are jacked! Physically and mentally. Thanks for the information. Awesome!
incredible video, the explanation in general helped me a lot but especially the transition from NAD+ to NADH+H+ and the final release of the electrons, thank you very much!!!
Bro explained the whole respiration in just 7 mind👏👏 wow
You have no idea how clutch this explanation is. insane.
THANK YOU! I was struggling with the concept of NAD+ vs NADH but understood everything else in my materials. Thank you for breaking it down, you made it make sense!!!
Mike, you are an absolutely amazing teacher! Please keep doing your job and we will support you!
Been doing nad+ iv infusions a couple of times a month. Loved the breakdown you gave =D
I have an auto immune disease so my white blood cell count has been high for the past 13 years. It causes constant fatigue.
I was just wondering if NAD helped you with fatigue?
What has it helped you with?
@@Robmancan1987 Ozone therapy should help with that
Goddamn that’s expensive lmao, I’ve got my first this Saturday
@@rickyspanish9625 don’t blasphemy
I haven't reviewed my Biochemical pathways in Years. This is a fantastic refresher
Wow, finally understand why I’m getting energy from my NAD+ boosters. Living the fasting and NAD boosted life!! Love this video, thanks!!!
What brand of nad+ you take ? Thank you
Yes which one ?
Kara Langley , do you know for me dietary fats and fasting causing me a dizzyness is this because of nad difficency?
Healthy diet
Thank you so much. I was searching the internet for hours trying to figure out a good explanation for the electrons and determining where they come from. I could hug you right now. No one explains this well. Mostly because I think people don't understand themselves. :)
I am from India 🇮🇳 and I love this video thankyou Sir 😊
You're such an exceptional teacher and I'm here for it!
Phenomenal explanation! Wish I had this from an enthused professor about 12 years ago during my Microbio undergrad!
Lol right? I had the guy that droned on with the monotone voice...while my head bobbed uncontrollably as I dozed off! 😴💤
I wished my ion pumps put out that kinda heat... My funny currents are low
This Guy has a gift of explaining things!!
I might just have found the best video on UA-cam
I’ve been getting off meds and even felt tired just walking. It’s been HELL. I just started taking NMN+ and I actually had energy to walk my dogs today and feel like I can run a mile! I’m not sure how long this will last but I’m taking advantage of it. I got a months worth and will keep taking it. Even if it only works today just having the energy is a godsend. And want to be clear it’s not a jittery kinda energy like coffee or any drug. It’s a very calm energy where I can sleep if I really wanted to or go out and not be dragging. It’s very nice to feel energetic again.
How are you now?
...this channel is so *chef's kiss*.
Thank you so much! I was watching a Biology video on Khan Academy and they just assumed we knew all about NAD+ forming NADH and then ATP, and 'explained' it in a very brief and hard to understand way! Thanks to you, I understood it crystal clear!
Glad it was helpful!
You advice me to take NAD
Legendary stuff! I take NMN and sometimes nad+ and THAT makes sooo much sense! Thanks legend! Have a good one! Karl, Gold Coast, Australia
Doc lookin jacked and jacked on science too. Love it! Thanks for the info
what have i been doing my whole life and where were you 2 years ago when i was in my 9th grade, one of the best lecture, helped me out a lot thank youuuuuuuuuuuuuuu
I cant understand how being handsome and smart could be in one body.
I am sitting here having an NAD infusion the doctor gave me, and trying to understand why NAD is going to give me this promised energy. You explained it perfectly, Dr. Mike.
I was staring at his arms the whole time. He’s got some great guns! 💪🏻 💪🏻
You explained it so well! Not even a person with PhD could do it like that! Thanks!
What does that even mean? That he’s not as smart as someone with a PhD? Or they you really look up to people with PhDs?
@@teddybearroosevelt1847
Nuance, my dude. I don’t think they actually believe mean a PhD wouldn’t be able to grasp this.
Mike Todorovic (PhD) & Dr. Matt Barton (PhD) are Senior Lecturers and Medical Researchers at Griffith University, Australia.
@@teddybearroosevelt1847 oh lords no. I had a teacher who supposedly did his PhD but I didn't understand one bit. Not that I'm insulting anyone, I was just exaggerating cuz typically people with PhD don't tend to simplify what they explain to, say, someone like me who wouldn't understand complicated terms.
tldr : i was exaggerating
this is the only vid ive found that actually helped me understand cellular respiration
Bro you literally explain way better than my university teacher LOL
Thanks for it, I was really stuck in a Wrong idea about Nad+ (the part about the Nadh + H) and you really killed my doubt 🙏🙏
hi doc, im a spanish student and i was able to understand everything. your explanation was so neat and i undertood even more than in my native language. i don't know if you ever will read this, but could you do a video of NADP? i would really appreciate it a lot. greetings from chile
Bravo 👏 I went back to my Chemistry class
Dr. Mike is an incredibly good teacher.
Thanks! You explained it in a wonderful comprehensive way! Although i struggle to understand chemistry.
Is it good for my body?What does it do to my body and take it?What's the side effect
Which is better nad+ injection or L -carnitine injections?
Inquiring minds need to know.
My basic understanding of creatine is that it also helps produce ATP. So, does it do this on it's own or is creatine kind of useless without NAD after a certain point?
Thank you🌹.it's easier to understand when the marker and white board is used since we get time to see and grasp what is explained.
Simple yet amazing explanation! Thanks!
This is golden, thank you very much for your quality videos and content overall.
It's amazing how some people are so people smart. Man, watching this guy's video is equivalent to watching 10 other UA-cam videos on the subject, if not more!
You are really genius n competent. I need this information from long time ago. Many thanks, Dr
I get it, I get it, I get it.. I’m so happy. I’m reading a book called Mitochondrial Dysfunction and it’s so good, but I really needed to understand, glycolysis and kreb cycle to really understand what’s happening. I was not making sense to me.. after this video I’m mind blown and how wonderful the human body is.. OMG
Such a complicated process - well explained.
4:17- The reaction is not balanced. The left should be added one more H⁺: NAD⁺ + 2e⁻ + 2H⁺ because two hydrogen atoms, 2H, are involved. But the right side appears correct if the H in NADH was a hydride (i.e. H⁻ , a proton and two electrons). If so, the left should be: NAD⁺ + H⁻ (2e⁻ + H⁺) + H⁺.
New to the channel, thank you for making each and every one of your videos, they are well done, very informative and break down the subject matter in a very understandable, efficient and productive manner, my classmates and I are very grateful for your hard work and continued inspiration, the effort you put into your craft is very much appreciated and has helped to not only meet but to exceed our expectations, please keep up the great work Dr.😁
Thank you. Simplified a very complex concept for me.
Excellent narration of complex topic in very easy manner ..respect🥰
Best explanation I’ve see yet
So that means, NAD+ gives more energy to the mitochondria which helps the mitochondria to produce more energy to the cell which help the cells grow. Can i explain it this way?
Hi Doc, I've seen some research on NAD+/NADH and the potential anti-aging benefits... could you comment on that? and also would it make a difference in whether you take NAD+ or NADH supplements? I also read in some journals that the NAD+/NADH ratio changes as we age but I'm not sure if there is enough research to support that... your input would very much be appreciated!!!
its in the H, allows for more water absorption. More water = healthier.
Bro mind EXPLODED (in a good way) Thanks for the content and allowing us to actually understand
I have no idea what any of that means, but it sounds important, so I’m glad it happens I suppose!
It's very important. We die instantly without this process. As we age our NAD+ levels decrease making things difficult for our bodies to function the way they used to.
@@lucky2653 NAD is essentially an electron carrier that then creates a gradient across the inner membrane of the mitochondria. Which makes hydrogen go through a protein complex called “ATP synthase” and ATP is ultimately produced from this. It makes ADP fuse with another phosphate :)
Yeah I'm glad my body is smarter than me.😂
@@Robmancan1987 lol
Supplements NAD, NR, NMN, NAD+, NADH…. all ultimately doing the same thing? Any of these the better choice?
This makes a lot of sense. If I am trying to take a supplement for energy, Does this mean I want to take NAD+ or NADH? From your demonstration here, it seems like the better supplement is NAD+
Another amazing video!! Really love watching your lectures simply because of how you break down the concept and make it much more easier to grasp. Thank you sir! :)
dude you just helped me answer a question on my bio quiz! thanks!
That was so well explained and I still didn't grasp it completely. I understand the outline and will have to watch again. But great simple explanation.
You nailed it, bro. Thanks a lot, I understood it the first time in life.
If only you were my teacher, I would have been more interested in chemistry. I did not have a Chem passionate professor till college, it ruined my high school life.
Excellent!! Great presentation !!! Thanks for that, Doc!
I have been struggling to understand the process , thank you so much. This video is outstanding.
Hello,
What’s the collateral effects of injecting NAD?
What’s the difference between an injection that cost 500$ and 1.500$ ?
Perfect explanation 🎉 my chemistry teachers during my form 6 and lectures during my biochemistry class were ALL a great failure by NOT able to teach this pathway appropriately . Thank you Mike 😊
What is the absorption rate for ingesting pills instead of getting infusions?
Wowza, loved this video and the great explanation! 😊
Than you for this explanation. It really helped me to understand the benefits of NAD🙂
Dr Matt, Muscle Man, very cool explanation! BTW, the best NAD+ is liposomal. ⚛💕☮🌎🌌
I just wanted to learn about NAD+ and NADH and ended up understanding the whole respiration thing 10 times better. Great video (and gains)
Sir, I have many doubt on this topic thank you so much❤ for clearing my doubt....you are such a great teaching skill...
Once again thank you sir...
Love from India ❤❤❤
I love man u'r great teacher you have my all respect 🙏 ❤
I know you used glucose as an example, but what if you are doing keto and using fat as your fuel? Does it work the same way?
I took 260 mg of nicotinamide adenine dinucleotide and it was no placebo. Increased energy, mood, and focus all day long. I’m going to proceed with caution until more research is done on its tumorigenic potential and impact on sirtuens, but damn.
I’m not going to name the manufacturer in case someone thinks I have a vested interest, but this stuff works.
Obviously consult your doctor before taking any supplements.
Brand please
Yes honest man. Dont care: b r a n d please !
I'm not a doctor or medical student but I'm passionate when comes to fitness. This I easily understood with no struggle
do you want a medal kid
You are so great at making this all make sense! Can you help me understand the "spike proteins" etc????
Is it a coincidence that this video was recommended to me after watching Tim Pools experience with COVID??
Lol guess I’m not the only one. Through me off bc I look into all of this but never heard of nad till pool said something.
@@steffytheking wait, hold on, what did he say?
@@im_so_bored3896 it was one of the things he received when he was diagnosed with covid iirc.
@@steffytheking ooooh ok then. thx. i heard they did a study on it and covid. and it shortened the recovery time.
Wow, you've cleared all my doubts
Thank you 😊
hope you do more biochem vedios ,cz its really help
I was struggling to understand this topic at school, now i finally get it
I've got a question, now ok we get 2 NADH + 2H+ in Glycolysis which needs 4 hydrogens. What about the Krebs cycle where we make 6 NADH + 6H+ and also the 2FADH2. Where do those hydrogens come from?
What happens with fatty acids instead of glucose? What does the + mean?. What is a carrier molecule?
Excellent video! I take NAD+ as a supplement! According to many studies, it is likely to be beneficial in human longevity!
Have you noticed any benefits?
Doc, can 15 yrs old take NAD+ iv drip?
It means that If a diabetic patient takes a high dose of NAD, it may help him to regulate energy expenditure along with DM reversal in long run.
WOW! VERY TECHNICAL, BUT CLEARED TO UNDERSTAND
Thanks a lot, this actually helped way more than the textbook!
What is the difference between Nicotinamide adenine dinucleotide hydrate
And
Nicotinamide adenine dinucleotide lyophilized
so helpful!! i wish you were my professor
Verrrrry goood Dr. Mike. Verrrry good.
I’ve have never seen one of your videos, Nice job breaking it down. Thank You!
Doc, do you reccomend a specific brand that we can buy?
❤
I still don't really know the benefits of NAD+ therapy. But it was good chemistry explanation :).