Very good until the end when IDL and LDL exit the liver as plaque under the endothelium which further promotes the old argument of atherosclerosis and heart disease without any explanation of the original injury to the epithelial wall, which caused the injury in the first place.
Dr. mike, you are awesome. The way you break everything down and explain the meaning behind the terms is amazing. So helpful, please don’t stop making these videos.
Sir i really dont know hw to thank u ...u r really doing a great job ...everyday atleast once i think about ur lectures n u mean a lot in my educational career ...please do continue explaining many more medical topics so that students like us are likely to be much benefitted ....jus cant thank enough ...all i can do is blow lots of love peace and good health to u and ur family 🥰🥰🥰💝
Thank you for the detailed explanation of lipid transport and digestion. Truly wonderful!! Since this video was created there has been some very important work done regarding LDL and Cardiovascular Disease. Please see Dr. Malcolm Kendrick's book, "The Clot Thickens". In that book he details the reasons why LDL cannot "deposit" on our arterial endothelium. Instead, it is the high pressure in the arteries and damage to the glycocalyx that causes the injuries that form clots, to which the LDL respond in order to REPAIR the damage.
I'm in med school and I've got to tell you that you're video lectures is 1000x better than my university teachers. They're not exactly "bad" teachers but there's an incredible difference in the amount of knowledge I leave with having watched your video, in comparison to their more "sterile" approach. Pun super intended.
Thank you so much. I need to report this exact process. My class intructor does not want to explain these that's why she gave it as a reporting in our class. I have been crying because she wants it to be very detailed and this is the only video I find helpful in all explanations. thank you so much❤ Hope you continue to upload more lectures.
your videos have saved my butt! My professor has a tendency of saying things backwards or mixing things up. You are are so straight forward and have awesome diagrams that I can draw and follow along with. Your videos are the shortest and most helpful ones ive come across! a million times thank you!
I have not studied since 2009 and gone back to university as a mature age student. Your videos are the most easiest to understand for and I really enjoy watching them! Please do more content!
Your content is amazing! You are the only doctor who has been able to explain everything so easily, making my studies easier. Thank you! Keep making awesome content!💯
I literally never NOT skip ads but I watched this one because every Dr. Mike video I watch brings me closer to being a doctor of veterinary medicine! :) thank you dr mike for your help in finishing my degree!!! and you look so cute while doing it
5:05 - "So here's the deal OK the CCK tells the gallbladder to contract, thus squeezing the bile down the bile duct and squirt it into the duodenum". Dr. Mike: "PERFECT".
The way u explain everything in detail is awesome. The clarity and explaining in simple words makes it so easy to understand. You are too good. Would love to meet u atleast once in my life ❤
Excellent - Tip#1 : Use fresh markers(green) ! Look at the faded marker ink on this vital info ! Such an easy fix. Such superb teaching ! Tip#2: Improve (slow down), clarify your handwriting (print like an architect not like a doctor (Ha ! emoji here)
What determines whether free fatty acids are sent to skeletal muscle for energy usage or to adipose tissue for energy storage? Is it insulin? I have yet to find a thorough fat metabolism explainer such as this one that goes so far as to include the Usage vs Storage selection process. Perhaps the video I'm looking for is one for metabolism of mixed macros, such as carbs and fats together.
Ur way to teach : Excellet Ur looks : Excellent No. of times Im distracted by ur looks: Excellent. Btw Im really grateful to u for making this topic a tequila shot for me.
Brilliant explanation and thank you . I have a question . Does the cholesterol lay down in the blood vessels because the body signals that there is injury and it is trying to repair? The body always seems to have a reason ?
Wait a minute.. you said that when fasting you will produce more LDL cholesterol, which then is likely to be deposited in arteries and causes Atherosclerosis? This seems to go against the fasting argument for improved health amd longevity? Is this correct or am I missing something?
Thank you doctor !! I have a question that Why the monoglycerides and fatty acids get to lymphatic system /duct/ to reach the blood stream that is different from protein and carbs( where they travel through liver for further modification) ?
One thing i do noy quite understand. The tryglicerides from the chylomicrons are being processed (snapped from the glycerol) by the lipoprotein lipase and the free fatty acids are being stored into (fatt cells) adipose tissue for energy storage. So far so good. But why doesn’t the lipoprotein lipase (in the bloodstream) process the tryglicerides from the liver packed into VLDL, LDL the same way? As far as I understand the latter and mainly the small dense LDL causes arteriosclerosis. Are tryglicerides from our diet being treated differentely then the tryglicerides from the liver?
Approximately where in the small intestines do to the majority of the lipids get absorbed by the enterocytes? Based on the structure of the Jejunum compared to the Ilium I figured this would occur mostly in the jejunum (because of the higher quantity of lacteals) but my A&P instructor says it's in the Ilium. I thought it was at the distal end of the ilium that the bile acids are reabsorbed not the lipids. The lipids were passed on earlier on in the small intestines. Can someone clear this up for me?
I’m tryin to figure out how to turn my carb dominated diet, which causes constant battle against obesity, to fat + protein based diet. My body has 50 years of experience of using carb snacks every 2 hours to kick out the feeling of hunger. Now I noticed, that adding few centiliters of vegetable oil to coffee, kicks out the hunger for many hours. But it does not give instant feel-good affect, like carbs do. Then I started to prepare the sunflower coffee in tha shaker. The oil almost gets emulsified with coffee, and then the mouth releases:”oh yeah, this tastes food” hormone to body to take another sip, and another.. like carbs do. Now I’m wondering if emulsified fat turns quicker to glucose. Regardles if or not, I’m looking for simple way to emulsify sunflower. May be one micro drop of dishwashing detergent… That’s what I’m about to try once I have finished this comment. I tell the result in reply in hour or two.
Today my breakfast was: A cup of tea with 4 cl of sunflower oil first shaken without any emulsifier, and then adding a 1/100 of droplet of dishwashing liquid. Latter one made tea creamlike foody drink, which keeps the hunger away many hours. I’ve been fasting on/off for half year and now, once my waisteline is in harmony with my esthetique requirements, I try to learn to feed my body only to what I consume, to not make energy banks around the waste. Thanks for delivering information in very comprehensive manner.
this is hands down the best video on this topic, trust me I’ve looked. Thank you soo much!
Very good until the end when IDL and LDL exit the liver as plaque under the endothelium which further promotes the old argument of atherosclerosis and heart disease without any explanation of the original injury to the epithelial wall, which caused the injury in the first place.
In his words: fasting contributes to atherosclerosis. Nonsense
Glucose imbalance
Dr. mike, you are awesome. The way you break everything down and explain the meaning behind the terms is amazing. So helpful, please don’t stop making these videos.
Sir i really dont know hw to thank u ...u r really doing a great job ...everyday atleast once i think about ur lectures n u mean a lot in my educational career ...please do continue explaining many more medical topics so that students like us are likely to be much benefitted ....jus cant thank enough ...all i can do is blow lots of love peace and good health to u and ur family 🥰🥰🥰💝
Thank you for the detailed explanation of lipid transport and digestion. Truly wonderful!! Since this video was created there has been some very important work done regarding LDL and Cardiovascular Disease. Please see Dr. Malcolm Kendrick's book, "The Clot Thickens". In that book he details the reasons why LDL cannot "deposit" on our arterial endothelium. Instead, it is the high pressure in the arteries and damage to the glycocalyx that causes the injuries that form clots, to which the LDL respond in order to REPAIR the damage.
THE BEST MD LECTURE ABOUT FAT DIGESTION I HAVE EVER WATCHED AND STUDIED ....
I'm in med school and I've got to tell you that you're video lectures is 1000x better than my university teachers. They're not exactly "bad" teachers but there's an incredible difference in the amount of knowledge I leave with having watched your video, in comparison to their more "sterile" approach. Pun super intended.
Wow, thank you! ☺️
Thank you so much. I need to report this exact process. My class intructor does not want to explain these that's why she gave it as a reporting in our class. I have been crying because she wants it to be very detailed and this is the only video I find helpful in all explanations. thank you so much❤ Hope you continue to upload more lectures.
your videos have saved my butt! My professor has a tendency of saying things backwards or mixing things up. You are are so straight forward and have awesome diagrams that I can draw and follow along with. Your videos are the shortest and most helpful ones ive come across! a million times thank you!
I have not studied since 2009 and gone back to university as a mature age student. Your videos are the most easiest to understand for and I really enjoy watching them! Please do more content!
Your content is amazing! You are the only doctor who has been able to explain everything so easily, making my studies easier. Thank you! Keep making awesome content!💯
Amazing. Love how it starts with basics and then moves to details.
I have sent this to my professor and nursing friends! Incredible! Truly.❤
you're literally my go-to channel in every lessons because of how you explain details into really understandable informations. Thanks a lot, Dr. Mike!
I literally never NOT skip ads but I watched this one because every Dr. Mike video I watch brings me closer to being a doctor of veterinary medicine! :) thank you dr mike for your help in finishing my degree!!! and you look so cute while doing it
Love uh Dr. Mike. You are a life saver, I have my final exam tomorrow
That was great. I learned more in 5 minutes than all the educational material I read. Well done.
Really really clear and helpful for someone who has little biochemistry knowledge. Thank you.
5:05 - "So here's the deal OK the CCK tells the gallbladder to contract, thus squeezing the bile down the bile duct and squirt it into the duodenum".
Dr. Mike: "PERFECT".
feel like i just watched a christopher nolan film. so complex and so amazing
Proud that your Australian. Excellent teacher. 🙏
Best explanation I ever seen
This was amazing, made me do such an amazing recap before my physiology exam
The way u explain everything in detail is awesome. The clarity and explaining in simple words makes it so easy to understand. You are too good. Would love to meet u atleast once in my life ❤
Absolutely amazing, don't know how you manage to make it so clear and understandable!!
Sir thank you very much for great lectures very clear and easy to understan💯👏👏👏
Thank you so much sir for this unforgettable lesson ❤
Thank you so much for spending your valuable time to teach us with marvellous methods ❤
Excellent instructor. Explains things very clearly.
Excellent thank you. Very informative and so well explained
A round of applause. This video is a masterpiece
You are the best!!!!! Love your lectures.
You are just amazing sir,,,, love your teaching method more than say❤️.
Thank you for explaining so well.
I rarely comment on youtube but you sir are amazing
This is a brilliant summary; thank you very very much 😊
hands down for this man. very well explained. thanks a lot
Thank you so much sir...very well explained
ITS VERY CLEAR, VERY SIMPLE, didnt skip any important points. how can you do that!
You are very clear and concise! Thanks a lot for your effort.
Wonderfully detailed video! Very nice
Thank you very much for the fantastic lecture, very clear and easy to understand.
Thank you Sir UR explanation is AMAZING.....
Excellent - Tip#1 : Use fresh markers(green) ! Look at the faded marker ink on this vital info ! Such an easy fix. Such superb teaching ! Tip#2: Improve (slow down), clarify your handwriting (print like an architect not like a doctor (Ha ! emoji here)
Thankyou Doctor ,very helpful videos,short precise and to the point.👍
This guy is brilliant. Running out of superlatives now.
Thankyou very much, it helps me a lot on learning biochemistry✨✨
Please do a video on carbohydrate digestion!
Best explanation ever
This one has really worked for me good Job sir
Honestly, amazing stuff!! Thank you.
explained so well! thank you so much
Thank you soooooooo much! I had a hard time on this area.
thanks dr for the great lecture
You’re a supppppppppper star and life saver thanks
قمرر يا دكتور مات ❤️❤️شرح اكتر من رائع
من مصر i love you♥️♥️
What determines whether free fatty acids are sent to skeletal muscle for energy usage or to adipose tissue for energy storage? Is it insulin? I have yet to find a thorough fat metabolism explainer such as this one that goes so far as to include the Usage vs Storage selection process. Perhaps the video I'm looking for is one for metabolism of mixed macros, such as carbs and fats together.
Ur way to teach : Excellet
Ur looks : Excellent
No. of times Im distracted by ur looks: Excellent.
Btw Im really grateful to u for making this topic a tequila shot for me.
Love your digestive videos
So nice and clear .... thank you 🙏
I like your video, I use it for my students. I was surprised seeing you with mustache
Great explanation
Sir, it is a grate video. Even layman can understand your video. Request you to share similar video on ‘Digesting carbohydrates’ flow
Please make video on bile duct injury
You definitely saved me. Thank you very musche
Glad I could help!
love from Sindh, Pakistan😊❤
you are amazing doctor
thank you so much
I dont have a gallblader and is why i have bloating and gas depends on what i eat ??
Brilliant explanation and thank you . I have a question . Does the cholesterol lay down in the blood vessels because the body signals that there is injury and it is trying to repair? The body always seems to have a reason ?
You are awesome! Thank you so much!
Please do a video on how vitamins ADEK fits in the process
you're the best i swear
Great lectures ! Thank you
youre my hero
🙈
Wait a minute.. you said that when fasting you will produce more LDL cholesterol, which then is likely to be deposited in arteries and causes Atherosclerosis?
This seems to go against the fasting argument for improved health amd longevity?
Is this correct or am I missing something?
Thank you doctor !! I have a question that Why the monoglycerides and fatty acids get to lymphatic system /duct/ to reach the blood stream that is different from protein and carbs( where they travel through liver for further modification) ?
Thank you so much sir 😊
Thanks, sir!❤
One thing i do noy quite understand. The tryglicerides from the chylomicrons are being processed (snapped from the glycerol) by the lipoprotein lipase and the free fatty acids are being stored into (fatt cells) adipose tissue for energy storage. So far so good.
But why doesn’t the lipoprotein lipase (in the bloodstream) process the tryglicerides from the liver packed into VLDL, LDL the same way? As far as I understand the latter and mainly the small dense LDL causes arteriosclerosis. Are tryglicerides from our diet being treated differentely then the tryglicerides from the liver?
Love ur energy. ❤
Hello Dr.Mike, love your presentation video. I would like to ask if Lipases need to be active if the pH level is around 7.35 - 7.45?
they wouldn’t be. hes saying they only work in basic environment
Muito obrigada! Amei a explicação. Muito boa mesmo. Consegui entender finalmente. Thank you very much.
Excellent!
If this can be added subtitle that will be perfect.
Approximately where in the small intestines do to the majority of the lipids get absorbed by the enterocytes? Based on the structure of the Jejunum compared to the Ilium I figured this would occur mostly in the jejunum (because of the higher quantity of lacteals) but my A&P instructor says it's in the Ilium. I thought it was at the distal end of the ilium that the bile acids are reabsorbed not the lipids. The lipids were passed on earlier on in the small intestines. Can someone clear this up for me?
do you do online teaching ?
Concept 🔥
I’m tryin to figure out how to turn my carb dominated diet, which causes constant battle against obesity, to fat + protein based diet.
My body has 50 years of experience of using carb snacks every 2 hours to kick out the feeling of hunger.
Now I noticed, that adding few centiliters of vegetable oil to coffee, kicks out the hunger for many hours.
But it does not give instant feel-good affect, like carbs do.
Then I started to prepare the sunflower coffee in tha shaker. The oil almost gets emulsified with coffee, and then the mouth releases:”oh yeah, this tastes food” hormone to body to take another sip, and another.. like carbs do.
Now I’m wondering if emulsified fat turns quicker to glucose.
Regardles if or not, I’m looking for simple way to emulsify sunflower.
May be one micro drop of dishwashing detergent…
That’s what I’m about to try once I have finished this comment. I tell the result in reply in hour or two.
Today my breakfast was:
A cup of tea with 4 cl of sunflower oil first shaken without any emulsifier, and then adding a 1/100 of droplet of dishwashing liquid.
Latter one made tea creamlike foody drink, which keeps the hunger away many hours.
I’ve been fasting on/off for half year and now, once my waisteline is in harmony with my esthetique requirements, I try to learn to feed my body only to what I consume, to not make energy banks around the waste.
Thanks for delivering information in very comprehensive manner.
So cholesterol increases during calorie deficits and fasting ?
This was very helpfull today ;o) thanks DrMike
Can fat storage occur without insulin? Damage normally occur due to glycat ion caused by excess carbs
Best one!!
So good thank u
فدوه شون شرح يخبل 😞💗💗
Is cholesterol the cause of inflammation? Or is it the first-aid that was delivered to the site of inflammation?
No mention of the body's requirements for cholesterol. No mention of the effects of glucose on apoB100.
As someone who has a non responsive celiac disease with fat malabsortion, the problems is then relatednto the pancreas ot rhe stomach acid ?
Thank you sir
thank you SO much
Love your tutorials. However, is the moustache real?
So,does this.mean that when we fast for a long time,our LDL level goes up?
well constructed tutorial... thank you