Fat Digestion - Lipolysis & Lipid Transport

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  • Опубліковано 26 лис 2018
  • What happens to the fats that we eat?
    In this video, Dr. Mike discusses how and where we digest lipids (triglycerides, cholesterol, and phospholipids) and how we transport them around the body.
    He also introduces the lipoproteins and highlights the differences between chylomicrons, VLDL, IDL, LDL, and HDL's. Focusing on cholesterol management.

КОМЕНТАРІ • 126

  • @michaelirwin1887
    @michaelirwin1887 Рік тому +18

    Very good until the end when IDL and LDL exit the liver as plaque under the endothelium which further promotes the old argument of atherosclerosis and heart disease without any explanation of the original injury to the epithelial wall, which caused the injury in the first place.

    • @user-mv8rw8hd6r
      @user-mv8rw8hd6r Місяць тому +1

      In his words: fasting contributes to atherosclerosis. Nonsense

  • @grochef
    @grochef Рік тому +15

    Thank you for the detailed explanation of lipid transport and digestion. Truly wonderful!! Since this video was created there has been some very important work done regarding LDL and Cardiovascular Disease. Please see Dr. Malcolm Kendrick's book, "The Clot Thickens". In that book he details the reasons why LDL cannot "deposit" on our arterial endothelium. Instead, it is the high pressure in the arteries and damage to the glycocalyx that causes the injuries that form clots, to which the LDL respond in order to REPAIR the damage.

  • @birdscrytoo
    @birdscrytoo 9 місяців тому +10

    this is hands down the best video on this topic, trust me I’ve looked. Thank you soo much!

  • @phanikumar4402
    @phanikumar4402 5 років тому +37

    Sir i really dont know hw to thank u ...u r really doing a great job ...everyday atleast once i think about ur lectures n u mean a lot in my educational career ...please do continue explaining many more medical topics so that students like us are likely to be much benefitted ....jus cant thank enough ...all i can do is blow lots of love peace and good health to u and ur family 🥰🥰🥰💝

  • @KH3Art
    @KH3Art 2 роки тому +16

    Dr. mike, you are awesome. The way you break everything down and explain the meaning behind the terms is amazing. So helpful, please don’t stop making these videos.

  • @gina4168
    @gina4168 3 місяці тому +1

    Amazing. Love how it starts with basics and then moves to details.

  • @user-wb6je6mw5x
    @user-wb6je6mw5x 6 місяців тому

    you're literally my go-to channel in every lessons because of how you explain details into really understandable informations. Thanks a lot, Dr. Mike!

  • @mostfuncked4551
    @mostfuncked4551 Рік тому +3

    your videos have saved my butt! My professor has a tendency of saying things backwards or mixing things up. You are are so straight forward and have awesome diagrams that I can draw and follow along with. Your videos are the shortest and most helpful ones ive come across! a million times thank you!

  • @lawsonsimons-px8pe
    @lawsonsimons-px8pe 9 місяців тому

    I have sent this to my professor and nursing friends! Incredible! Truly.❤

  • @dalidali2757
    @dalidali2757 2 роки тому +1

    THE BEST MD LECTURE ABOUT FAT DIGESTION I HAVE EVER WATCHED AND STUDIED ....

  • @Demi-8
    @Demi-8 3 роки тому +2

    Love uh Dr. Mike. You are a life saver, I have my final exam tomorrow

  • @metsutai
    @metsutai 4 роки тому +2

    You are very clear and concise! Thanks a lot for your effort.

  • @layaldergham45
    @layaldergham45 Рік тому +1

    I literally never NOT skip ads but I watched this one because every Dr. Mike video I watch brings me closer to being a doctor of veterinary medicine! :) thank you dr mike for your help in finishing my degree!!! and you look so cute while doing it

  • @kyms1862
    @kyms1862 2 місяці тому

    I have not studied since 2009 and gone back to university as a mature age student. Your videos are the most easiest to understand for and I really enjoy watching them! Please do more content!

  • @seokdoespilates
    @seokdoespilates 2 роки тому +3

    Really really clear and helpful for someone who has little biochemistry knowledge. Thank you.

  • @MA4TU2
    @MA4TU2 3 місяці тому

    That was great. I learned more in 5 minutes than all the educational material I read. Well done.

  • @ktmilliken1860
    @ktmilliken1860 2 роки тому +2

    Excellent instructor. Explains things very clearly.

  • @saadfallah1237
    @saadfallah1237 4 роки тому +3

    Absolutely amazing, don't know how you manage to make it so clear and understandable!!

  • @jellycopter007
    @jellycopter007 4 роки тому +3

    Thank you very much for the fantastic lecture, very clear and easy to understand.

  • @jkipoiuoty2
    @jkipoiuoty2 11 місяців тому

    The way u explain everything in detail is awesome. The clarity and explaining in simple words makes it so easy to understand. You are too good. Would love to meet u atleast once in my life ❤

  • @lanahamerlitz5926
    @lanahamerlitz5926 2 роки тому +1

    This was amazing, made me do such an amazing recap before my physiology exam

  • @neelo14
    @neelo14 4 роки тому +2

    Thankyou Doctor ,very helpful videos,short precise and to the point.👍

  • @noeliaprietoschwartzman273
    @noeliaprietoschwartzman273 2 роки тому +3

    Thank you for explaining so well.

  • @eyadakhras3521
    @eyadakhras3521 Рік тому +1

    This is a brilliant summary; thank you very very much 😊

  • @choonghuh
    @choonghuh Місяць тому

    feel like i just watched a christopher nolan film. so complex and so amazing

  • @melgu9355
    @melgu9355 2 роки тому +2

    You are the best!!!!! Love your lectures.

  • @weddjammal9413
    @weddjammal9413 3 роки тому

    ITS VERY CLEAR, VERY SIMPLE, didnt skip any important points. how can you do that!

  • @xlalouba
    @xlalouba Рік тому +2

    Excellent thank you. Very informative and so well explained

  • @guest-zn8zs
    @guest-zn8zs 10 місяців тому

    Wonderfully detailed video! Very nice

  • @Hamo4differentvideo
    @Hamo4differentvideo Рік тому +1

    Best explanation I ever seen

  • @estiakshakil2663
    @estiakshakil2663 2 роки тому +2

    You are just amazing sir,,,, love your teaching method more than say❤️.

  • @yoe91
    @yoe91 2 роки тому +2

    5:05 - "So here's the deal OK the CCK tells the gallbladder to contract, thus squeezing the bile down the bile duct and squirt it into the duodenum".
    Dr. Mike: "PERFECT".

  • @deekircher21
    @deekircher21 4 роки тому +1

    Great lectures ! Thank you

  • @thatdancinggirl9882
    @thatdancinggirl9882 4 місяці тому

    A round of applause. This video is a masterpiece

  • @zaarahussain3552
    @zaarahussain3552 2 роки тому +1

    Thank you Sir UR explanation is AMAZING.....

  • @Chipalo_with_a_c
    @Chipalo_with_a_c 7 місяців тому

    Honestly, amazing stuff!! Thank you.

  • @kiranmayivemuri5813
    @kiranmayivemuri5813 2 роки тому +2

    Thank you so much sir...very well explained

  • @jaytran247
    @jaytran247 3 роки тому +2

    thanks dr for the great lecture

  • @zakirzak1494
    @zakirzak1494 3 роки тому +1

    So nice and clear .... thank you 🙏

  • @abdullahahmed7604
    @abdullahahmed7604 2 роки тому +1

    explained so well! thank you so much

  • @ilyaskhanilyaskhan4787
    @ilyaskhanilyaskhan4787 2 роки тому +3

    Sir thank you very much for great lectures very clear and easy to understan💯👏👏👏

  • @mekonnenmengistu7332
    @mekonnenmengistu7332 9 місяців тому

    Great explanation

  • @anapaulacastro1534
    @anapaulacastro1534 3 роки тому +2

    Muito obrigada! Amei a explicação. Muito boa mesmo. Consegui entender finalmente. Thank you very much.

  • @lawsonsimons-px8pe
    @lawsonsimons-px8pe 9 місяців тому

    Thank you soooooooo much! I had a hard time on this area.

  • @filmonhaile3327
    @filmonhaile3327 4 роки тому +2

    I rarely comment on youtube but you sir are amazing

  • @rogersssemwogerere5590
    @rogersssemwogerere5590 3 роки тому

    This one has really worked for me good Job sir

  • @alyaagamal5907
    @alyaagamal5907 2 роки тому

    Best explanation ever

  • @aldinstuart5787
    @aldinstuart5787 10 місяців тому

    Excellent!

  • @eoinmcsweeney2632
    @eoinmcsweeney2632 8 місяців тому

    Love ur energy. ❤

  • @iaprawitasari3028
    @iaprawitasari3028 Рік тому

    Thankyou very much, it helps me a lot on learning biochemistry✨✨

  • @treramirez109
    @treramirez109 2 місяці тому

    You are awesome! Thank you so much!

  • @Hi-ny6iq
    @Hi-ny6iq 2 роки тому +1

    you are amazing doctor
    thank you so much

  • @dodi8086
    @dodi8086 Рік тому

    You’re a supppppppppper star and life saver thanks

  • @user-ix6wq6nj3i
    @user-ix6wq6nj3i 2 роки тому

    قمرر يا دكتور مات ❤️❤️شرح اكتر من رائع
    من مصر i love you♥️♥️

  • @sovannypond-tor8867
    @sovannypond-tor8867 5 місяців тому

    thank you SO much

  • @megburrows1398
    @megburrows1398 2 роки тому

    So good thank u

  • @asuramunikavishadesilva371
    @asuramunikavishadesilva371 Місяць тому

    Thanks, sir!❤

  • @Catchfish201
    @Catchfish201 25 днів тому

    well constructed tutorial... thank you

  • @somasekhar4331
    @somasekhar4331 2 роки тому

    Sir, it is a grate video. Even layman can understand your video. Request you to share similar video on ‘Digesting carbohydrates’ flow

  • @ludelyntejada3239
    @ludelyntejada3239 Рік тому

    Thank you sir

  • @doinagorenco739
    @doinagorenco739 Рік тому

    Thank you!!!

  • @shohrehmousavi2090
    @shohrehmousavi2090 3 роки тому

    Thank you!

  • @martinford76
    @martinford76 3 роки тому

    This was very helpfull today ;o) thanks DrMike

  • @sanamsomani3404
    @sanamsomani3404 5 років тому +2

    Please make video on bile duct injury

  • @user-oj3uj9uj3r
    @user-oj3uj9uj3r 5 років тому

    amazing thanks a lot

  • @randdawoud5960
    @randdawoud5960 Рік тому

    you're the best i swear

  • @foreverrainbow3566
    @foreverrainbow3566 Рік тому +1

    You definitely saved me. Thank you very musche

  • @whittenoval
    @whittenoval Рік тому +1

    This guy is brilliant. Running out of superlatives now.

  • @mrabin8098
    @mrabin8098 3 роки тому +1

    Best one!!

  • @retnomurwani7226
    @retnomurwani7226 3 роки тому +1

    I like your video, I use it for my students. I was surprised seeing you with mustache

  • @alaamohamed3211
    @alaamohamed3211 3 роки тому

    Thank u very much

  • @patriciamartin6309
    @patriciamartin6309 8 місяців тому

    Brilliant explanation and thank you . I have a question . Does the cholesterol lay down in the blood vessels because the body signals that there is injury and it is trying to repair? The body always seems to have a reason ?

  • @xeff3280
    @xeff3280 3 роки тому +1

    Approximately where in the small intestines do to the majority of the lipids get absorbed by the enterocytes? Based on the structure of the Jejunum compared to the Ilium I figured this would occur mostly in the jejunum (because of the higher quantity of lacteals) but my A&P instructor says it's in the Ilium. I thought it was at the distal end of the ilium that the bile acids are reabsorbed not the lipids. The lipids were passed on earlier on in the small intestines. Can someone clear this up for me?

  • @j7ndominica051
    @j7ndominica051 3 роки тому

    Does medium and short chain enter the blood as triglycerides, and require for all 3 fatty acids to be short, or does it enter as free fatty acids and can be sourced from mixed triglycerides?

  • @sakurabonita9905
    @sakurabonita9905 2 роки тому

    Please do a video on how vitamins ADEK fits in the process

  • @hschaufeld
    @hschaufeld 2 роки тому

    you're my hero

  • @Olivia-ck6jz
    @Olivia-ck6jz 2 роки тому

    فدوه شون شرح يخبل 😞💗💗

  • @janetmosquera4628
    @janetmosquera4628 2 роки тому +1

    I dont have a gallblader and is why i have bloating and gas depends on what i eat ??

  • @DaveMcCammon
    @DaveMcCammon Рік тому

    Wait a minute.. you said that when fasting you will produce more LDL cholesterol, which then is likely to be deposited in arteries and causes Atherosclerosis?
    This seems to go against the fasting argument for improved health amd longevity?
    Is this correct or am I missing something?

  • @Heisenberg.1927
    @Heisenberg.1927 2 роки тому +1

    Concept 🔥

  • @user-qq9it4vn7p
    @user-qq9it4vn7p 4 місяці тому

    Wow doctor ❤❤❤❤

  • @andrewnguyen5837
    @andrewnguyen5837 Рік тому +1

    Hello Dr.Mike, love your presentation video. I would like to ask if Lipases need to be active if the pH level is around 7.35 - 7.45?

    • @doctorposting
      @doctorposting Рік тому

      they wouldn’t be. hes saying they only work in basic environment

  • @Loonapopyoutube
    @Loonapopyoutube 2 роки тому +3

    youre my hero

  • @Roozy_Persepolis
    @Roozy_Persepolis Рік тому

    So,does this.mean that when we fast for a long time,our LDL level goes up?

  • @effiechen1027
    @effiechen1027 Рік тому

    If this can be added subtitle that will be perfect.

  • @attahussain7559
    @attahussain7559 Рік тому

    love from Sindh, Pakistan😊❤

  • @peterleighton4716
    @peterleighton4716 Рік тому

    If you fast more frequently, does this mean that you are at a higher risk for vascular disease due to very low density lipoproteins?

  • @ntnjadeabdulhadi3386
    @ntnjadeabdulhadi3386 Рік тому

    do you do online teaching ?

  • @DeltaSanjula
    @DeltaSanjula Рік тому

    So what happens to this process if the gallbladder is removed?

  • @telegnes4500
    @telegnes4500 3 роки тому

    Love your tutorials. However, is the moustache real?

  • @tarunleegos4940
    @tarunleegos4940 2 роки тому +1

    Ur way to teach : Excellet
    Ur looks : Excellent
    No. of times Im distracted by ur looks: Excellent.
    Btw Im really grateful to u for making this topic a tequila shot for me.

  • @johnnyb620
    @johnnyb620 5 років тому

    Could it be implied that people who are long term ketogenic adapters, will eventually develop atherosclerosis?

    • @DrMattDrMike
      @DrMattDrMike  5 років тому +1

      johnnyb620 too difficult to say. The current evidence says that increased saturated dietary fats + cholesterol will increase likelihood for atherosclerosis. However, there are multiple other contributing factors such as genetics, that are significantly influential.

    • @mtofta
      @mtofta 3 роки тому +5

      @@DrMattDrMike This is old and outdated research. New research has proven that saturated fats are good. Why no mentioning of fats and ketone bodies as effective energy source?

  • @GingerWaters
    @GingerWaters 2 місяці тому

    I’m tryin to figure out how to turn my carb dominated diet, which causes constant battle against obesity, to fat + protein based diet.
    My body has 50 years of experience of using carb snacks every 2 hours to kick out the feeling of hunger.
    Now I noticed, that adding few centiliters of vegetable oil to coffee, kicks out the hunger for many hours.
    But it does not give instant feel-good affect, like carbs do.
    Then I started to prepare the sunflower coffee in tha shaker. The oil almost gets emulsified with coffee, and then the mouth releases:”oh yeah, this tastes food” hormone to body to take another sip, and another.. like carbs do.
    Now I’m wondering if emulsified fat turns quicker to glucose.
    Regardles if or not, I’m looking for simple way to emulsify sunflower.
    May be one micro drop of dishwashing detergent…
    That’s what I’m about to try once I have finished this comment. I tell the result in reply in hour or two.

    • @GingerWaters
      @GingerWaters 2 місяці тому

      Today my breakfast was:
      A cup of tea with 4 cl of sunflower oil first shaken without any emulsifier, and then adding a 1/100 of droplet of dishwashing liquid.
      Latter one made tea creamlike foody drink, which keeps the hunger away many hours.
      I’ve been fasting on/off for half year and now, once my waisteline is in harmony with my esthetique requirements, I try to learn to feed my body only to what I consume, to not make energy banks around the waste.
      Thanks for delivering information in very comprehensive manner.

  • @sanamsomani3404
    @sanamsomani3404 5 років тому

    Please make video on varicose vein

  • @bigcat9977
    @bigcat9977 3 роки тому +1

    Is cholesterol the cause of inflammation? Or is it the first-aid that was delivered to the site of inflammation?

    • @andywong8786
      @andywong8786 3 роки тому +3

      No mention of the body's requirements for cholesterol. No mention of the effects of glucose on apoB100.

  • @MnrBugi
    @MnrBugi 4 дні тому

    So indeed, eating fats does not increase triglycerides in the blood as these are transported through the lymphatic system.
    Only in a fasting state, triglycerides are transported from the liver and hence in the blood.
    BUT doesn't this also mean, the body will be exposed to fat soluble toxins because they aren't sent through the liver? 🤔

  • @kimcruz3889
    @kimcruz3889 Рік тому

    soo. IS IT BAD TO FAST?? 😀

  • @Amelia-jk6bh
    @Amelia-jk6bh Місяць тому

    who needs a cheeseburger when you can make us full

  • @sw121fy
    @sw121fy 8 місяців тому

    I like your Mustache doctor

  • @drTERRRORRR
    @drTERRRORRR 2 роки тому +1

    Freddie in med-school?