Currently on a five day , I’ve done several three day fasts . I have healed many things through fasting. Brain is alive again, pain has diminished all over body .
Today is Day 5 and I feel amazing! Highly recommend for everyone. Do it! You won’t regret it. You may not be able to do 5 days right away. Try one meal a day first, then try intermittent fasting where you don’t eat breakfast and stop late night eating. Practice your ability to say no to food.
That means so much to me, Hector - I've been working on clearing up my style and improving how I communicate, so your comment really means a lot - thank you.
Triglycerides remaining higher at three months compared to d0 might be caused by the increase of fat metabolism imprinted by the 5day fasting. In other words, metabolism versatility improves
finally something healthy for me to binge ;) your videos! lol i've been practicing forms of prolonged fasting and intermittent fasting for just over a year now, but i REALLY need to get my head back in the game. 70 more lbs to go for me til my ideal weight (20 down in the year i've been going). i've mostly been doing 24s and 48s, longest i've gone is 6.5 days! wanting to master 7 days. videos like these keep me motivated and focused!!
I did lab work on a 4 day water fast and saw doctor same day . My BP went from 150/90 to 110/70. Cholesterol was surprisingly high. Fasting glucose usually around 100 on previous test, this time was 73 after 4 days fasting.
There's a fasting protocol for lipid test. See the fasting method. It's like two weeks before labs cycle eating every four hours throughout the day. Fasting dumps lipids into the bloodstream. Gives artificial number mine was 70 points until I learned this.
Thx for the Video. Why are people so focused on water fasting? IMO i consider the Heal-fasting by Dr. Otto Buchinger as superior. His "water- fasting" allowed the patient to cook a vegetable broth (no eating, just drinking the broth once a day instead of only-water) to counter the head-achs and loss of vitamins.
@@Physionic the idea of Dr. Buchinger (from year 1935) focused to prevent side effects such as headaches, circulatory disorders or flatulence while water-fasting for a long time period; 10-12 days. Basic Rules of the modern version: Before the water fasting: - consult your Doctor; with some health conditions, fasting is risky. - 1-3 Preparation/Relief-days. Cook and eat only steamed or porriged vegetable. (There are variations eating rice) While Fasting: - every 2-3 days: Clean the intestines with enema or an irrigator (if possible) - Sport and/or Yoga are recommended to prevent muscle-loss. - Cook the vegetable broth (no salt, just vegetables, herbs and water) and drink 200 - 400 ml each day - selfmade vegetable juice (fe. tomato, carrot) once per day are also allowed. Optional: - Meditation - "liver wrap" (Warm water bottle around your stomach/liver for 30-40 minutes.) After the fasting: - Start slow for 1-2 days with mostly eating vegetables and fruits, cooked and steamed food that is easy for your digestions. - Change your eating habbits; Withdrawel from sugar-addiction.
Fabulous video and longer term insights. I only do shorter fasts up to 48 hrs end of wk on top of time restricted feeding each day and eat healthy whole foods - mainly Flexitarian/Mediterranean (not Keto which will cause large leaps in lipids on fasting). I do however take fish oil tablets and a few other supplements to lower triglycericides and LDL/VLDL each meal (as well as BSL) despite that my lipid/BSL profile are normal, before I start a fast. Many people on intermittent fasting long term have improved lipid profiles but I believe it really depends on your diet and your original levels. ie I think your 2 hypotheses are both correct. LDL transports cholesterol from liver to peripheral tissues including the adrenal glands and gonads for both hormone synthesis and cell membrane repair and it is known that cortisol does increase somewhat in fasting. Triglycerides are mobilized and used for fuel after conversion to ketones to spare what little glucose is left for brain use so they should be elevated during your fast. They however will also be elevated if you keep eating lots of fats during refeeding or if you eat too many carbs without also increasing your fiber intake. The other thing is exercise. If you aren't burning them off, you are storing them.
Good video. It appears, from your videos on fasting and insulin and my own experience ( int-fasting, and 3 and 5 day ) the key takeaway may very well be, resetting or calibrating insulin-resistance greatly enhancing benefits of healthier diet going forward. Lots of good avenues for further research and myth-busting ; addressing goals, ie, fat loss, vs weight (muscle ) gain and body chemical upkeep/balances. and there is no secret to overcome genetic disposition... it's harder for some, impossible for some, and easy for some.
Great content and presentation! Thank you. In terms of why TG are higher, if ones body becomes more dual fuel (sugar/fat) as a result of fasting, what if our body then sees more utility in fat based fuels - like TG? Interested to get your perspective on this as the PhD in the room :)
@@Physionic I'm Curious, If You Could Personally Choose A System For Better Health And Mitochondria Production, Would It Be Fasting Or Eating Very Heathy and Hard Interval Training?
Awesome! as always! very nice video! would be nice to see in the future, some comparison about fasting versus caloric déficit. i personally think that any "benefit" from fasting can be achieved by a caloric déficit...
@@alvarocoronel67 Yes, it happens, kind of always happening, we do not need to fast for days for it to happen, even the break between meals can increase autophagy, also exercise and lack of nutrients.
I believe this is dependant on your body weight/body fat % when you are in a caloric deficit. Body builders frequently go into caloric deficits in preparation for shows; during this period they frequently report feeling significantly worse and generally feel much better during the off-season where they go into a caloric surplus. So if you're at a high body fat %, I speculate a caloric deficit would probably have similar benefits to a fast as you have the resources to burn through whereas at a lower % body fat this is not the case.
Weight creeping back after fasting is not an issue. I hope nobody believes fasting is a magic trick to get you slim -- you still have to put in effort to keep your gains after you have achieved them. Thinking you can fast *once* for 5 days and be slim forever is like thinking you can run daily for a month and be healthy for life. Not monitoring body composition is really poor study design here. You want to understand how much of that weight loss was fat and how much was muscle / everything else. I think the most important results of a 5 day water fast is not weight loss itself -- a lot of it is usually regained soon. The most important results are overall health improvements, especially reduced insulin resistance as well as mental improvements -- it trains your willpower and gives you sense of accomplishment. Personally, I have been running throughout my week long fast. On my second day my performance dropped severely, but about day 4-5 it started going back up. After couple of days of refeeding my performance and especially endurance jumped much higher than before I started the fast -- my suspicion being improved ability to burn fat improving my running at my slow speeds.
Dr Ekberg explains the cholesterol phenomenon on his video where he fasted for 100 hours. I'm not exactly sure (because I haven't studied medicine) but apparently one has to look deeper at the Ldl - p because the increase is in the good fluffy ones and not the dense ones.
very easy to follow content! I’m very new to the channel but enjoy how digestible (no pun intended) your content is. I think I’ll try a 7 day fast and see what occurs.
"I have been practicing fasting for five years now, and despite having a BMI of 19, my cholesterol levels have remained high for the past three years. Recently, I have noticed signs of poor circulation in my extremities, and my blood pressure tends to be on the low side. I am feeling somewhat apprehensive about the potential long-term effects on my blood vessels."
Thank you for the video but I am so confused. I do a 48 hour fast once a week for almost 2 years and I also do keto for the next 2.5 days immediately following my fast (have been doing that for the last 7 months). My triglycerides plummetted since when I first started doing the fast and continues to be very low now. My LDL was high before I started the fast and spiked up since the fast and recently improved by 20% but still more elevated than my doctor is comfortable with. I continue to resist taking the statins per doctor's recommendation. My bp was 130/80 before fasting and now like 110/80. But I did lose a bunch of weight I'm sure helped with the bp. Was 165 lbs and now between 143 lbs to 150 lbs. Anyway super confused about elevated triglyceride from your video in light of my results.
Nice work with the presentation. There are health benefits to fasting however I would imagine there is greater muscle loss because to build muscle you need protein intake every 4 hours.
One thing that comes in mind is that people mind also change their behavior/approach to food/eating after the study. I mean, for me for example, fasting showed me that cravings might come not from physiological needs (i.e. I need energy) but from psychological "needs" - i.e. eating will help me avoid some emotions I do not want to feel. So, after fasting, I chnaged my relationship with food and started choosing a bit different food etc. So, the question is if the people changed their habits/approach to food after the fasting.
Great video, do you know whether just balanced diet with local fresh food and some fresh meat and fasting and moderate exercise is key to longevity. There are tons of video of carni crazy bashing vegan and vice versa
A part of this puzzle that is missing is what is being consumed during refeeding as well as after departing for the remaining 3 months. If you have insulin resistance why would you return to the diet that got you there?
How did prescriptions and supplements factor into water fasting? Are their certain vitals one should track closely during a fast? Are there certain people who should not fast?
For the finding of higher triglycerides after 3 months, did the study subjects have their calorie and macronutrient consumption tracked during this period? The explanation might be behavioral--i.e. after the 5 day fast was over, maybe the deprivation triggered some long-term "poorer" eating habits--(the body thinks periodic famine conditions may be a regular occurrence in the future, therefore, test subjects become more "fat seeking" in their dietary choices)
the increase in TG could be that the body got used to utilizing more fats even when glucose is available. When i started cardio fasted i was very week at first but after weeks of training i was much better, and even after a good period of not fasting i felti kept these gainz for a long time. I also remember to start getting irritable when hungry and trembeling and after a few mornings of fasting it went away forever even if i eat normaly, as long as i fast occasionally.
Raised cholesterol is the body’s reaction to stress. Cholesterol being used to build glucocorticoids like adrenaline and cortisol. Cortisol causes insulin resistance. It makes sense from a survival standpoint. The body says, “I better become insulin resistant so I can store any shave I encounter as fat”. Metabolism is thereafter lowered and excess energy is saved in the form of fat via insulin resistance.
What is your opinion? I am diagnosed NAFLD, and my enzymes were around 550 after a 48 hour fast (I am/was a heavy drinker until the last few weeks also)... after those results I have cut back alcohol to rarely... and I have been losing weight with keto/occasionally 24-36 hour fasts... is the fasting causing more damage than it is repairing due to the weight loss?
Just done 5 days 17 hours. Felt like needed to break out of boredom. Black tarry diarrhea past day or so. Broke fast with couple pieces bread and butter. Tin of chicken stock. Banana muffin and now couple of yoghurts. Lost 5 kg+. Worked out during fast. First two days worst. Days 3 and 4 okay. Made my mind you to crack 5 days. Wasn't hungry and could have continued but felt bored not eating
Omg you never come off a fast like that 😮you come off a fast with veggies or fruits only read Dr fungs book on fasting , or look up Cole Robertson the snake diet guy he does a lot of research about fasting ! He has a bit of a potty mouth yells a lot but he is very good at this fasting stuff, worth a looks❤
Cortisol is probably off the charts. I did a 7 day water fast, felt like crap. Didn't lose not one pound. I didn't do any blood test though and at the time I had Cushing's.
My thoughts on elevated TRG after the fast. As was mentioned the weight came back. So they had calories surplus. Since they probably were on standard carb centric diet the excess of carbs was converted into fats and being delivered to tissue by TRG.
It's probable that they were in a surplus, I hear you there, les. Thanks for adding your input, I'm trying to get more people to speculate a bit - it's fun.
I wonder what effect taking statins would have during the high cholesterol period mid fast. Would this lead to more rapid weight loss or even greater use of fat stores? Or would it be very harmful?
I have a potential explanation. I watched a video about cholesterol- wish I could tell you the name or anything- wherein it explained that all cholesterol was actually the same and whether it was good or bad had to do with how it is directed. That's the very simplistic explanation from a non-doctor me, so be patient. They said something about triglycerides raising after a fast because the body is doing much more repair work than it had been doing before the fast. That's all I have for you to work with.
colestrol raise is quite normal, liver already makes 80% of the colestrol , by not eating the fuel source is body fat , colestrol is essential, it is the carb in the mix thats the problem
Thank you for this topic. I would like to do this sort of fast to improve metabolic health (and potentially longevity through autophagy) but I don't have the reserves to do so healthily. This is suppose, is where Prolon saw a gap in the market as a treatment protocol for those with chronic illness or who lack the willpower to comply with a water fast unsupported.
@@littlevoice_11 I did Prolon for four months. My triglycerides dropped 50 points. My overall blood panel much improved, including glucose. But very little weight due to a medication that I have to take for chronic illness. At least I maintained a 30 lb weightloss from previous ketogenic regimen. My focus now is uric acid and associated illnesses, and I have problems with research that does not include differentiation between ages, health status and sex. I have been tempted to recreate the Prolon diet by making my own food, the marketing of their product and the expense kinda bug me. That would mean it kinda boils down to calorie restriction. Oh! And I think these cycles of fasting have to be repeated for long term effects.
@@littlevoice_11 I was horrified re sugar level as a strict ketogenic follower, but I fell for the explanation by Longo. My daily numbers that I monitor were never better….it appeals to me Longo’s life as Pescatarian and vegetarian, but so does Carnivore. Seems calorie restriction, carb reduction, insulin control is key on all.
one possible explanation for the cholesterol at 3 months is that they may have been able to break their addiction to sugars and changed their diet to a more protein-based diet. Just one possible variable
For triglycerides and cholesterol...Could it be that the lack of nutrients hardens the veins and arteries walls? The body might need to lubricate as a compensation. If this is stupid, please disregard. I am not in the medical profession, just using average Joe logic.
Valtor longo said that the body resets its ability to use fat as fuel during a 5 day fast, so these increases in ldl/hdl would concur with that. Also he said the benefits come from autophagy and stem cells being released months after the fast. More UA-camrs really should interview him
Well the triglycerides staying high is alarming. I've been curious about doing this for quite some time but have never felt fully comfortable with the idea. I just keep collecting information. Thank you for doing this series.
I have done fasting for 3 to 4 days like 3 times in my life and on the contrary my triglycerides crashed very low endeed, my cholesterol goes up tho, I have read studies that note that triglycerides actually get significantly low with fasting and that’s what makes sense biochemically.
The liver doesn’t produce cholesterol particles to transport fat. It produces lipoproteins which transport fat, cholesterol, liposoluble vitamins, etc. It is important to make that distinction. LDL and HDL are not cholesterol. They are vessels for various substances, including cholesterol. Having said that, I don’t really care about cholesterol or lipoprotein numbers. I don’t believe they are at all causal in heart disease.
Isn't the cholesterol elevated because we simply run on our own saturated fat ? This leads to a hypothesis if only the presence of LDL cholesterol in blood is bad, as carnivore people often asking.
Hey doc, can you please do a video about tightening skin with fasting. I ve seen your skin video but don't remember that specifically. Love the channel btw. Just discovered. Also love your call out videos as well!🙂
@@lynntrovert2471 so far it seems like fasting is helping me. I have lost 90 plus pounds in last year. I have very little loose skin. Under arms and belly. But I have been doing a 5 day straight fast every month plus mostly intermittent fasting. Like I say, seems to be working and loose skin I do have seems to be tightening slowly as well.
im curious to see what these types of fasts do with muscle and organ tissue. claims exist of muscle preservation, and/or that muscle and organ tissues restore after the fast, but im not confident in these claims. im so excited about this subject, as someone who has done multi-week water fasting.
Muscle mass is largely preserved, but after a time, there's definitely some loss. You'll have to tune in tomorrow for the multi-week fasting video, then, Cherryl.
It mostly depends how lean you are. A guy with 20% body fat will lose minimal quantity of muscle. A guy who is athlete around 10-12 % body fat will lose a lot of muscle. Since I am at about 12% bf I have tried this on myself and I lose muscle during my 2 day fast.
have a doubt bro please clarify me I want to loose weight My doubt was I will eat only 4 or 5 days in a week and remaining days are fasting until i reach my target my daily calorie deficit budget was 2300 Does my BMR will help me to loose weight in fasting days ? I mean can I count BMR calories in fasting day ???
Hm ... just thinking: One part of the weight loss from water fasting is the lack of glycogene and the water it holds in the body; the second - and likewise fast effect - is the loss of gut contents; both can in my experience sum up to 3-4 kilograms. That will be restored with a normal diet within a few days.
It's a mind thing if you believe in Jesus Christ ask him to walk you through it! We've been brainwashed since birth to believe we need food everyday 3 times a day !! Trust and believe if God demands fasting its Good for ya
Start slow. Skip a meal. Go to two meals a day, no snacks. Then one meal a day....thats 24 hours. Then after you've done OMAD for a week or two try 36 hours, then 48 hours.
2:182:36 :How do you come to the quick conclusion that they lost subtantial FAT withing 5 days of fasting, rather than primarily muscle mass? Doesn't muscle mass tend to go before fat? Isn’t “loss of weight => loss of body fat” precisely a common mistake? How is “weight” even a relevant indicator for anything but largely overweight people? (which as you point out is not even the case in this study) What did these people do in the lab for 5 days? Did they train or just zone in hypoglycemia limbo? In which case, what was the effect on training?
The cholesterol results are consistent with my similar (but not identical) experience, and consistent with "LDL hyperresponders". It would be interesting for Dr Ben Bikman to converse with "Dr Physionic".
I hear about so many people being healed but so far my goiter hasn't gone away . I really didn't want to have it surgically removed ... anyone hv success with goiter going back to normal size with fasting
When i was doing 10 days water fast i had high trigl. Slightly high colesterol, after 10 days i had my blood checked had loverd triglicerides and almost dubled cloesterol also had high lvls of uric best explantaion for this was given by Buchinger wilhelmy doctors in one of theyrs videos about long therm fasting should lookt them up if you havent jet thery work is great, ps ty for video always plesure to learn sonething new
Kako su poviseni trigliceridi pozotivna stvar? Ok insulin se smanjio ali se i vratio brzo, ali koliko vidimo trigliceridi se nisu vratili kao sto su bili pre
Cholesterol has gone up because the body is mobilising fat to be used for energy. There's more cholesterol in the blood stream because all triglycerides and fats in general are moving around from their stores to be used in target tissues.
Omigosh the triglyceride increase really scares me. I would never have thought this would happen. What is mineral water? Like, Smart Water? Can I drink LaCroix?
I've got an off topic question for you. Has anybody ever asked you if you're related to the late Buddy Holly? To me you look just like the man and not that that has anything to do with anything, but I was just curious. Great video though, very informative.
I'm starting day 5 of a 5 day fast, I've lost 11 pounds, or 4.68% of my total body weight. I started at 235 pounds, I'm sure that's above normal. Last year's 5 day fast I lost 10 pounds. What was interesting was I did my first 5 day fast last year, and it broke my food discipline I had formed dieting the previous year. I really struggled to get back to eating specific things at specific times
Fasting may not improve things dramatically unless you change your diet-and that includes basal insulin. I had dramatic weight loss fasting, but was only successful in keeping it off when I changed my macronutrients, reducing carbohydrates and processed foods (including seed oils.) PS: Virtually all the standard metrics for health improved, with the exception of LDL, because LDL is BS. My coronary artery calcium scan even went down to "zero."
So, Professor, have you done a five day fast? I would be afraid of passing out. A few years ago I lost a dear friend and subsequently lost my appetite for several weeks. I wasn’t fasting, but I definitely was not eating much. I had a blood test during this period and my total cholesterol was shockingly high. Maybe the result of utilizing fatty acids as fuel?
No, I haven't. There's been no need in my life, plus with me lifting weights religiously, it's counter to those goals. I'm sorry to hear about your friend; I can imagine that was extremely turbulent, emotionally. I certainly understand the lack of appetite; I've been there, myself. It's possible it was elevated for that reason, but that's just educated speculation on my part, Ariel.
@@Physionic That was probably the closest I came to fasting, but I remember when I did eat it was mostly this grain bread with something called coconut butter on it. So between not eating much but having this coconut butter, my cholesterol shot up. Just an observation.
@@PhysionicHa ha ha. I remember our PA who were assisting during many orthospine neurosurgeries… all of them dumped their heavy weights. No heavy liftings. The only activity they were doing: “religiously” swimming every day. 😂
@@Physionic yikes well I actually watched the video. Increased LDL does not sound good. I'm borderline high with 110 ldl and 95 apob and somewhat of a family cvd history. (But could have been due to others smoking). I should research this more before fasting regularly.
@@Physionic Thank you. You make some thought provoking videos. I need to go back and watch vids specifically about autophagy. Apoe4/3 so I am hoping to lower my AD chances. already slim and fit and minimal refined carbs and pretty good sleep. So perhaps some fasting.
If I make them any louder, the audio will clip. I set the audio to around -8dB. Not sure I can make it any louder without distorting the sound, unfortunately.
In my experience, fiber is the best way to reduce cholesterol numbers. When I was on a strict keto diet, my cholesterol was sky high. ApoB was 186. Switching to a high fiber diet (i.e. lots of legumes), literally cut that number in half. So of course, we aren't taking in fiber on a multi-day water fast, and cholesterol will increase.
![5 Stages of Extended Fasting [HUGE Benefits, Smoother Transitions, & More]](http://i.ytimg.com/vi/5OkEabJWQeQ/mqdefault.jpg)
![5 Stages of Extended Fasting [HUGE Benefits, Smoother Transitions, & More]](/img/tr.png)
![2 Week Water Fast: Is Longer, Better for Health? [Study 56]](http://i.ytimg.com/vi/4a4Pdg_1slc/mqdefault.jpg)
Currently on a five day , I’ve done several three day fasts . I have healed many things through fasting. Brain is alive again, pain has diminished all over body .
Wonderful news, Brian!
Why nobody talks about insomnia while prolong fasting?
@@sidjohnson1776 ~ True. Seems very common.
@@sidjohnson1776 some tlk about it....the ketosis energy the brin is getting is different from carb....
@@sidjohnson1776 I know, right?!
Today is Day 5 and I feel amazing! Highly recommend for everyone. Do it! You won’t regret it. You may not be able to do 5 days right away. Try one meal a day first, then try intermittent fasting where you don’t eat breakfast and stop late night eating. Practice your ability to say no to food.
I've not gone beyond 40 hours Fasting. Currently prepping for a 72-96 hour fast. You've got me very motivated to keep it up.
Dude… your presentation style and videos are Amazingly formatted. So clear, thorough, etc. Thanks so much for proper health science analysis 👍🏽🙏🏽
That means so much to me, Hector - I've been working on clearing up my style and improving how I communicate, so your comment really means a lot - thank you.
Triglycerides remaining higher at three months compared to d0 might be caused by the increase of fat metabolism imprinted by the 5day fasting. In other words, metabolism versatility improves
finally something healthy for me to binge ;) your videos! lol i've been practicing forms of prolonged fasting and intermittent fasting for just over a year now, but i REALLY need to get my head back in the game. 70 more lbs to go for me til my ideal weight (20 down in the year i've been going). i've mostly been doing 24s and 48s, longest i've gone is 6.5 days! wanting to master 7 days. videos like these keep me motivated and focused!!
Glad I can provide, Lucy :)
If you've only lost 20 pounds in a year I think you may want to reevaluate your strategy.
I did lab work on a 4 day water fast and saw doctor same day . My BP went from 150/90 to 110/70. Cholesterol was surprisingly high. Fasting glucose usually around 100 on previous test, this time was 73 after 4 days fasting.
Incredibly consistent with these results, wow! Thank you for sharing, ricky - hope you've been well!
There's a fasting protocol for lipid test. See the fasting method. It's like two weeks before labs cycle eating every four hours throughout the day. Fasting dumps lipids into the bloodstream. Gives artificial number mine was 70 points until I learned this.
Hmmm interesting stuff 🤔👏🏻 I’m loving these videos full of useful information 👍🏻🥰
Interesting study parameters and design 👍 Tq for bringing this to light . On On
Longer Water Fasting - Are there Greater Effects?: ua-cam.com/video/4a4Pdg_1slc/v-deo.html
Thx for the Video. Why are people so focused on water fasting? IMO i consider the Heal-fasting by Dr. Otto Buchinger as superior. His "water- fasting" allowed the patient to cook a vegetable broth (no eating, just drinking the broth once a day instead of only-water) to counter the head-achs and loss of vitamins.
I can't say I've heard of it, Berek. Would be nice to do a comparison.
@@Physionic
the idea of Dr. Buchinger (from year 1935) focused to prevent side effects such as headaches, circulatory disorders or flatulence while water-fasting for a long time period; 10-12 days.
Basic Rules of the modern version:
Before the water fasting:
- consult your Doctor; with some health conditions, fasting is risky.
- 1-3 Preparation/Relief-days. Cook and eat only steamed or porriged vegetable. (There are variations eating rice)
While Fasting:
- every 2-3 days: Clean the intestines with enema or an irrigator (if possible)
- Sport and/or Yoga are recommended to prevent muscle-loss.
- Cook the vegetable broth (no salt, just vegetables, herbs and water) and drink 200 - 400 ml each day
- selfmade vegetable juice (fe. tomato, carrot) once per day are also allowed.
Optional:
- Meditation
- "liver wrap" (Warm water bottle around your stomach/liver for 30-40 minutes.)
After the fasting:
- Start slow for 1-2 days with mostly eating vegetables and fruits, cooked and steamed food that is easy for your digestions.
- Change your eating habbits; Withdrawel from sugar-addiction.
Fabulous video and longer term insights. I only do shorter fasts up to 48 hrs end of wk on top of time restricted feeding each day and eat healthy whole foods - mainly Flexitarian/Mediterranean (not Keto which will cause large leaps in lipids on fasting). I do however take fish oil tablets and a few other supplements to lower triglycericides and LDL/VLDL each meal (as well as BSL) despite that my lipid/BSL profile are normal, before I start a fast.
Many people on intermittent fasting long term have improved lipid profiles but I believe it really depends on your diet and your original levels.
ie I think your 2 hypotheses are both correct. LDL transports cholesterol from liver to peripheral tissues including the adrenal glands and gonads for both hormone synthesis and cell membrane repair and it is known that cortisol does increase somewhat in fasting.
Triglycerides are mobilized and used for fuel after conversion to ketones to spare what little glucose is left for brain use so they should be elevated during your fast. They however will also be elevated if you keep eating lots of fats during refeeding or if you eat too many carbs without also increasing your fiber intake. The other thing is exercise. If you aren't burning them off, you are storing them.
Thanks, Talia. I appreciate it. I also appreciate the thoughtful and detailed response.
Good video. It appears, from your videos on fasting and insulin and my own experience ( int-fasting, and 3 and 5 day ) the key takeaway may very well be, resetting or calibrating insulin-resistance greatly enhancing benefits of healthier diet going forward. Lots of good avenues for further research and myth-busting ; addressing goals, ie, fat loss, vs weight (muscle ) gain and body chemical upkeep/balances. and there is no secret to overcome genetic disposition... it's harder for some, impossible for some, and easy for some.
thanks for the information, very informative!
My pleasure, Mark - thank you!
Thank you, very informative
I truly enjoy your content because you use hard science and actual studies to back up claims
Thank you, Riya. :)
great video again, clark
Thanks, Clark!
Great content and presentation! Thank you. In terms of why TG are higher, if ones body becomes more dual fuel (sugar/fat) as a result of fasting, what if our body then sees more utility in fat based fuels - like TG? Interested to get your perspective on this as the PhD in the room :)
Great topic. Thanks. ☘️☘️☘️☘️☘️
Subbed. Awesome content. 7 days dry water is far superior for the trouble.
Sounds Like Good Science To Me, I Like How You Finish The Story and Explain The Temporary Effects, Interesting About The Triglycerides! :)
More on that in the next few videos, Reed.
@@Physionic I'm Curious, If You Could Personally Choose A System For Better Health And Mitochondria Production, Would It Be Fasting Or Eating Very Heathy and Hard Interval Training?
Great video. What's your thoughts on a 5 day fast for people with kidney issues and gout? Beneficial or detrimental?
Many thanks Nick!
Thank you, Horea!
Awesome! as always! very nice video! would be nice to see in the future, some comparison about fasting versus caloric déficit. i personally think that any "benefit" from fasting can be achieved by a caloric déficit...
I'm really not sure - it's something that could be teased out, but if anyone has to any extensive degree, I'm not sure. Thanks, KK!
But what about the benefits of autophagy? Do you think these also happen with caloric deficit?
@@alvarocoronel67 Yes, it happens, kind of always happening, we do not need to fast for days for it to happen, even the break between meals can increase autophagy, also exercise and lack of nutrients.
I believe this is dependant on your body weight/body fat % when you are in a caloric deficit. Body builders frequently go into caloric deficits in preparation for shows; during this period they frequently report feeling significantly worse and generally feel much better during the off-season where they go into a caloric surplus.
So if you're at a high body fat %, I speculate a caloric deficit would probably have similar benefits to a fast as you have the resources to burn through whereas at a lower % body fat this is not the case.
Weight creeping back after fasting is not an issue. I hope nobody believes fasting is a magic trick to get you slim -- you still have to put in effort to keep your gains after you have achieved them.
Thinking you can fast *once* for 5 days and be slim forever is like thinking you can run daily for a month and be healthy for life.
Not monitoring body composition is really poor study design here. You want to understand how much of that weight loss was fat and how much was muscle / everything else.
I think the most important results of a 5 day water fast is not weight loss itself -- a lot of it is usually regained soon. The most important results are overall health improvements, especially reduced insulin resistance as well as mental improvements -- it trains your willpower and gives you sense of accomplishment.
Personally, I have been running throughout my week long fast. On my second day my performance dropped severely, but about day 4-5 it started going back up. After couple of days of refeeding my performance and especially endurance jumped much higher than before I started the fast -- my suspicion being improved ability to burn fat improving my running at my slow speeds.
Dr Ekberg explains the cholesterol phenomenon on his video where he fasted for 100 hours. I'm not exactly sure (because I haven't studied medicine) but apparently one has to look deeper at the Ldl - p because the increase is in the good fluffy ones and not the dense ones.
very easy to follow content! I’m very new to the channel but enjoy how digestible (no pun intended) your content is. I think I’ll try a 7 day fast and see what occurs.
Thank you, Bean. Good luck with yours.
"I have been practicing fasting for five years now, and despite having a BMI of 19, my cholesterol levels have remained high for the past three years. Recently, I have noticed signs of poor circulation in my extremities, and my blood pressure tends to be on the low side. I am feeling somewhat apprehensive about the potential long-term effects on my blood vessels."
Great Chanel! Out of curiosity - did you ever research the effects of fasting on autoimmune diseases (like systemic lupus) and chronic inflammation?
Not yet!
Thank you for the video but I am so confused.
I do a 48 hour fast once a week for almost 2 years and I also do keto for the next 2.5 days immediately following my fast (have been doing that for the last 7 months).
My triglycerides plummetted since when I first started doing the fast and continues to be very low now.
My LDL was high before I started the fast and spiked up since the fast and recently improved by 20% but still more elevated than my doctor is comfortable with. I continue to resist taking the statins per doctor's recommendation.
My bp was 130/80 before fasting and now like 110/80.
But I did lose a bunch of weight I'm sure helped with the bp. Was 165 lbs and now between 143 lbs to 150 lbs.
Anyway super confused about elevated triglyceride from your video in light of my results.
I cant wait for the research on the first ever 30 day fast... that will be so interesting. Great Video Nic!
Thanks, b. cage!
This supports my hypothesis that LDL increases because fatty acids are being used in higher amounts during a calorie deficit.
Nice work with the presentation. There are health benefits to fasting however I would imagine there is greater muscle loss because to build muscle you need protein intake every 4 hours.
One thing that comes in mind is that people mind also change their behavior/approach to food/eating after the study.
I mean, for me for example, fasting showed me that cravings might come not from physiological needs (i.e. I need energy) but from psychological "needs" - i.e. eating will help me avoid some emotions I do not want to feel.
So, after fasting, I chnaged my relationship with food and started choosing a bit different food etc.
So, the question is if the people changed their habits/approach to food after the fasting.
Hi! What about stomach dilation? Is a 5 days fasting effective to reduce stomach dimensions?
Great video, do you know whether just balanced diet with local fresh food and some fresh meat and fasting and moderate exercise is key to longevity. There are tons of video of carni crazy bashing vegan and vice versa
A part of this puzzle that is missing is what is being consumed during refeeding as well as after departing for the remaining 3 months.
If you have insulin resistance why would you return to the diet that got you there?
Could you talk about constipation and fasting? Thank you.
I love that study design as well. Wish I could participate in something like this.
How did prescriptions and supplements factor into water fasting? Are their certain vitals one should track closely during a fast? Are there certain people who should not fast?
For the finding of higher triglycerides after 3 months, did the study subjects have their calorie and macronutrient consumption tracked during this period? The explanation might be behavioral--i.e. after the 5 day fast was over, maybe the deprivation triggered some long-term "poorer" eating habits--(the body thinks periodic famine conditions may be a regular occurrence in the future, therefore, test subjects become more "fat seeking" in their dietary choices)
the increase in TG could be that the body got used to utilizing more fats even when glucose is available.
When i started cardio fasted i was very week at first but after weeks of training i was much better, and even after a good period of not fasting i felti kept these gainz for a long time. I also remember to start getting irritable when hungry and trembeling and after a few mornings of fasting it went away forever even if i eat normaly, as long as i fast occasionally.
Raised cholesterol is the body’s reaction to stress. Cholesterol being used to build glucocorticoids like adrenaline and cortisol. Cortisol causes insulin resistance. It makes sense from a survival standpoint. The body says, “I better become insulin resistant so I can store any shave I encounter as fat”. Metabolism is thereafter lowered and excess energy is saved in the form of fat via insulin resistance.
What is your opinion? I am diagnosed NAFLD, and my enzymes were around 550 after a 48 hour fast (I am/was a heavy drinker until the last few weeks also)... after those results I have cut back alcohol to rarely... and I have been losing weight with keto/occasionally 24-36 hour fasts... is the fasting causing more damage than it is repairing due to the weight loss?
Just done 5 days 17 hours. Felt like needed to break out of boredom. Black tarry diarrhea past day or so.
Broke fast with couple pieces bread and butter. Tin of chicken stock. Banana muffin and now couple of yoghurts. Lost 5 kg+. Worked out during fast. First two days worst. Days 3 and 4 okay. Made my mind you to crack 5 days. Wasn't hungry and could have continued but felt bored not eating
Omg you never come off a fast like that 😮you come off a fast with veggies or fruits only read Dr fungs book on fasting , or look up Cole Robertson the snake diet guy he does a lot of research about fasting ! He has a bit of a potty mouth yells a lot but he is very good at this fasting stuff, worth a looks❤
Cortisol is probably off the charts. I did a 7 day water fast, felt like crap. Didn't lose not one pound. I didn't do any blood test though and at the time I had Cushing's.
My thoughts on elevated TRG after the fast. As was mentioned the weight came back. So they had calories surplus. Since they probably were on standard carb centric diet the excess of carbs was converted into fats and being delivered to tissue by TRG.
It's probable that they were in a surplus, I hear you there, les. Thanks for adding your input, I'm trying to get more people to speculate a bit - it's fun.
So in conclusion you recommend it or not?
What is the (electronic synthesized?) woodwind music that comes in softly at the *very* end of the video?
Im on day 4 😊 my blood pressure has dropped from 169/98 to 129/87 😊
I wonder what effect taking statins would have during the high cholesterol period mid fast. Would this lead to more rapid weight loss or even greater use of fat stores? Or would it be very harmful?
Excellent you crushed it!!
My guess high cholesterol/trig is due to stress.
Thanks, Koi!
May be good to be on a Staten to lower cholesterol on a fast?
you have great hair!
I have a potential explanation. I watched a video about cholesterol- wish I could tell you the name or anything- wherein it explained that all cholesterol was actually the same and whether it was good or bad had to do with how it is directed. That's the very simplistic explanation from a non-doctor me, so be patient. They said something about triglycerides raising after a fast because the body is doing much more repair work than it had been doing before the fast. That's all I have for you to work with.
colestrol raise is quite normal, liver already makes 80% of the colestrol , by not eating the fuel source is body fat , colestrol is essential, it is the carb in the mix thats the problem
Thank you for this topic. I would like to do this sort of fast to improve metabolic health (and potentially longevity through autophagy) but I don't have the reserves to do so healthily. This is suppose, is where Prolon saw a gap in the market as a treatment protocol for those with chronic illness or who lack the willpower to comply with a water fast unsupported.
My pleasure, LV. Yes, FMD can be an alternative, then.
@@Physionic I was surprised by the macros on the diet for Prolon. It had added Sugars too
@@littlevoice_11 I did Prolon for four months. My triglycerides dropped 50 points. My overall blood panel much improved, including glucose. But very little weight due to a medication that I have to take for chronic illness. At least I maintained a 30 lb weightloss from previous ketogenic regimen. My focus now is uric acid and associated illnesses, and I have problems with research that does not include differentiation between ages, health status and sex. I have been tempted to recreate the Prolon diet by making my own food, the marketing of their product and the expense kinda bug me. That would mean it kinda boils down to calorie restriction. Oh! And I think these cycles of fasting have to be repeated for long term effects.
@@littlevoice_11 I was horrified re sugar level as a strict ketogenic follower, but I fell for the explanation by Longo. My daily numbers that I monitor were never better….it appeals to me Longo’s life as Pescatarian and vegetarian, but so does Carnivore. Seems calorie restriction, carb reduction, insulin control is key on all.
Good.
Here's my thought on cholesterol. The body has switch from burning glucose and went to fats stores for energy, thus releasing fat in the body. ?
so, umm... is that good?
6:39-6:47 suggests a level of pre-judgement. Surely the next study will help "make my point" but it might just as likely discount/discredit it.
i' m on day 7 the last one , i will break fast later with bone broth if I feel good I will continue till 10 days , do u recommend that ?
one possible explanation for the cholesterol at 3 months is that they may have been able to break their addiction to sugars and changed their diet to a more protein-based diet. Just one possible variable
Why tryglicerids were high? Should we "5 day fasters" worry?
For triglycerides and cholesterol...Could it be that the lack of nutrients hardens the veins and arteries walls? The body might need to lubricate as a compensation. If this is stupid, please disregard. I am not in the medical profession, just using average Joe logic.
Wonder what the results would be if you did this every two months.
Valtor longo said that the body resets its ability to use fat as fuel during a 5 day fast, so these increases in ldl/hdl would concur with that.
Also he said the benefits come from autophagy and stem cells being released months after the fast.
More UA-camrs really should interview him
Well the triglycerides staying high is alarming. I've been curious about doing this for quite some time but have never felt fully comfortable with the idea. I just keep collecting information. Thank you for doing this series.
True, although they aren't dangerously high, at least. Still, if it causes you to pause, Ellen, I certainly understand.
I have done fasting for 3 to 4 days like 3 times in my life and on the contrary my triglycerides crashed very low endeed, my cholesterol goes up tho, I have read studies that note that triglycerides actually get significantly low with fasting and that’s what makes sense biochemically.
Hey can someone tell me the video where he talks about the follow up study and/or about dyslipidemia resultsv
The liver doesn’t produce cholesterol particles to transport fat. It produces lipoproteins which transport fat, cholesterol, liposoluble vitamins, etc. It is important to make that distinction. LDL and HDL are not cholesterol. They are vessels for various substances, including cholesterol.
Having said that, I don’t really care about cholesterol or lipoprotein numbers. I don’t believe they are at all causal in heart disease.
Isn't the cholesterol elevated because we simply run on our own saturated fat ? This leads to a hypothesis if only the presence of LDL cholesterol in blood is bad, as carnivore people often asking.
Hey doc, can you please do a video about tightening skin with fasting. I ve seen your skin video but don't remember that specifically. Love the channel btw. Just discovered. Also love your call out videos as well!🙂
I'm interested in this too, have you found any good resources on it in the last two weeks? Thanks
@@lynntrovert2471 so far it seems like fasting is helping me. I have lost 90 plus pounds in last year. I have very little loose skin. Under arms and belly. But I have been doing a 5 day straight fast every month plus mostly intermittent fasting. Like I say, seems to be working and loose skin I do have seems to be tightening slowly as well.
@@KbeezyThe Good to hear. And good job. :)
im curious to see what these types of fasts do with muscle and organ tissue. claims exist of muscle preservation, and/or that muscle and organ tissues restore after the fast, but im not confident in these claims.
im so excited about this subject, as someone who has done multi-week water fasting.
Muscle mass is largely preserved, but after a time, there's definitely some loss.
You'll have to tune in tomorrow for the multi-week fasting video, then, Cherryl.
It mostly depends how lean you are. A guy with 20% body fat will lose minimal quantity of muscle. A guy who is athlete around 10-12 % body fat will lose a lot of muscle.
Since I am at about 12% bf I have tried this on myself and I lose muscle during my 2 day fast.
have a doubt bro please clarify me I want to loose weight
My doubt was
I will eat only 4 or 5 days in a week and remaining days are fasting until i reach my target my daily calorie deficit budget was 2300
Does my BMR will help me to loose weight in fasting days ?
I mean can I count BMR calories in fasting day ???
Hm ... just thinking:
One part of the weight loss from water fasting is the lack of glycogene and the water it holds in the body; the second - and likewise fast effect - is the loss of gut contents; both can in my experience sum up to 3-4 kilograms.
That will be restored with a normal diet within a few days.
Takes crazy willpower... I feel like i am starving not eating for 12 hours
It's a mind thing if you believe in Jesus Christ ask him to walk you through it! We've been brainwashed since birth to believe we need food everyday 3 times a day !! Trust and believe if God demands fasting its Good for ya
Start slow. Skip a meal. Go to two meals a day, no snacks. Then one meal a day....thats 24 hours. Then after you've done OMAD for a week or two try 36 hours, then 48 hours.
2:18 2:36 :How do you come to the quick conclusion that they lost subtantial FAT withing 5 days of fasting, rather than primarily muscle mass? Doesn't muscle mass tend to go before fat? Isn’t “loss of weight => loss of body fat” precisely a common mistake? How is “weight” even a relevant indicator for anything but largely overweight people? (which as you point out is not even the case in this study)
What did these people do in the lab for 5 days? Did they train or just zone in hypoglycemia limbo? In which case, what was the effect on training?
There is a lot of overlap in the error bars in some of these graphs, which makes me hesitant to give weight to some of the conclusions you espoused.
Any beneficial use of ApOA and ApOB instead of LDL and HDL ?
Yes - I'd argue a better metric than LDL, for certain.
The cholesterol results are consistent with my similar (but not identical) experience, and consistent with "LDL hyperresponders". It would be interesting for Dr Ben Bikman to converse with "Dr Physionic".
I hear about so many people being healed but so far my goiter hasn't gone away . I really didn't want to have it surgically removed ... anyone hv success with goiter going back to normal size with fasting
When i was doing 10 days water fast i had high trigl. Slightly high colesterol, after 10 days i had my blood checked had loverd triglicerides and almost dubled cloesterol also had high lvls of uric best explantaion for this was given by Buchinger wilhelmy doctors in one of theyrs videos about long therm fasting should lookt them up if you havent jet thery work is great, ps ty for video always plesure to learn sonething new
Very interesting to me, Jon - thank you for sharing your experience.
Kako su poviseni trigliceridi pozotivna stvar? Ok insulin se smanjio ali se i vratio brzo, ali koliko vidimo trigliceridi se nisu vratili kao sto su bili pre
Cholesterol has gone up because the body is mobilising fat to be used for energy. There's more cholesterol in the blood stream because all triglycerides and fats in general are moving around from their stores to be used in target tissues.
Omigosh the triglyceride increase really scares me. I would never have thought this would happen. What is mineral water? Like, Smart Water? Can I drink LaCroix?
LaCroix is fine. Keep in mind the triglyceride increase isn't massive, although still present.
My 3rd day I'm doing pretty good.. First two days was hell...
I've got an off topic question for you. Has anybody ever asked you if you're related to the late Buddy Holly? To me you look just like the man and not that that has anything to do with anything, but I was just curious. Great video though, very informative.
I'm starting day 5 of a 5 day fast, I've lost 11 pounds, or 4.68% of my total body weight. I started at 235 pounds, I'm sure that's above normal. Last year's 5 day fast I lost 10 pounds.
What was interesting was I did my first 5 day fast last year, and it broke my food discipline I had formed dieting the previous year. I really struggled to get back to eating specific things at specific times
Awesome! But keep in mind that when you start eating carbs again you'll gain some water weight but dont worry the fat will stay off ❤
Fasting may not improve things dramatically unless you change your diet-and that includes basal insulin. I had dramatic weight loss fasting, but was only successful in keeping it off when I changed my macronutrients, reducing carbohydrates and processed foods (including seed oils.)
PS: Virtually all the standard metrics for health improved, with the exception of LDL, because LDL is BS. My coronary artery calcium scan even went down to "zero."
My trigs went way down keto / fasts
I did a 3 day fast and went down two pants sizes going to start my 5 day fast today.
What's the issue with chronically high triglycerides?
It's associated with pancreatitis and arteriosclerosis, as two potential issues.
So, Professor, have you done a five day fast? I would be afraid of passing out.
A few years ago I lost a dear friend and subsequently lost my appetite for several weeks. I wasn’t fasting, but I definitely was not eating much. I had a blood test during this period and my total cholesterol was shockingly high. Maybe the result of utilizing fatty acids as fuel?
No, I haven't. There's been no need in my life, plus with me lifting weights religiously, it's counter to those goals.
I'm sorry to hear about your friend; I can imagine that was extremely turbulent, emotionally. I certainly understand the lack of appetite; I've been there, myself. It's possible it was elevated for that reason, but that's just educated speculation on my part, Ariel.
@@Physionic That was probably the closest I came to fasting, but I remember when I did eat it was mostly this grain bread with something called coconut butter on it. So between not eating much but having this coconut butter, my cholesterol shot up.
Just an observation.
@@PhysionicHa ha ha. I remember our PA who were assisting during many orthospine neurosurgeries… all of them dumped their heavy weights. No heavy liftings. The only activity they were doing: “religiously” swimming every day. 😂
can One drink coffee instead of just water? would that still count as fasting? regards.
Yes, you may drink black coffee or green tea as well
@@MsTumz473 thank You for your response. regards.
Would fasting 1 day per week do anything to boost autophagy? Would 3 consecutive days each month be better?
Speculatively, you'd still see increases in autophagy, but 3 days would lead to more.
@@Physionic yikes well I actually watched the video. Increased LDL does not sound good. I'm borderline high with 110 ldl and 95 apob and somewhat of a family cvd history. (But could have been due to others smoking). I should research this more before fasting regularly.
Fortunately, values went back to normal pretty soon after the fast, so keep that in mind, Matthew.
@@Physionic Thank you. You make some thought provoking videos. I need to go back and watch vids specifically about autophagy. Apoe4/3 so I am hoping to lower my AD chances. already slim and fit and minimal refined carbs and pretty good sleep. So perhaps some fasting.
So fasting is a terrible idea for those with high cholesterol numbers.
check out the buchinger Wilhelmini studies!
I just did, Julia - you may have blown my mind. Haha. I'm definitely going to dig into this - thank you.
Videos are usually low in volume, hard to hear at times
If I make them any louder, the audio will clip. I set the audio to around -8dB. Not sure I can make it any louder without distorting the sound, unfortunately.
In my experience, fiber is the best way to reduce cholesterol numbers. When I was on a strict keto diet, my cholesterol was sky high. ApoB was 186. Switching to a high fiber diet (i.e. lots of legumes), literally cut that number in half. So of course, we aren't taking in fiber on a multi-day water fast, and cholesterol will increase.
Why the f*ck would you care about "sky high" cholesterol. We are not in the 60s anymore. Stop being brainwashed.
I am going to be starting a 10 day fast tomorrow!
Good luck, Katia. :)
Keep us posted.
interesting
Glad you think so - as do I!