Vitamin B1-Thiamin(e) Deficiency-----So many symptoms!--Part 1
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- Опубліковано 23 лют 2022
- Vitamin B1-Thiamin(e) Deficiency-----So many symptoms!--Part 1
Dr. Derrick Lonsdale
“It is a critical and rate-limiting co-factor to multiple enzymes involved in this process, including those at the entry points and at critical junctures for the glucose, fatty acid, and amino acid pathways.”
“thiamine availability dictates molecular oxygen homeostasis and mitochondrial ATP production.”
Thiamin dependent enzymes: there are more than the 5 listed.
1. Transketolase
2. Pyruvate Dehydrogenase Complex
3. 2-Hydroxyacyl-CoA Lyase
4. Branched Chain Keto-Acid Dehydrogenase
5. Alpha-Ketoglutarate Dehydrogenase Complex
Recommended daily intake men 1.2 mg and women 1.1mg
B vitamins are water-soluble, so they dissolve quickly in the body. Half life 1-12 hours with approx. 30 mg stored muscle, heart, brain, liver and kidneys which can be depleted in 2-3 weeks. Or with acute illness it can be depleted in as little as 72 hrs. Absorbed in the jejunum of the small intestine by diffusion.
Thiamin deficiency is rare in the US but sub-optimal levels are quite common. True deficiency is called Beri Beri which cause damage to nerves, muscles and cardiovascular system.
Wet beri beri-cardiovascular system(shortness of breath, tachycardia) and edema
Dry beri beri-nervous system, N/T in hands and feet, confusion, memory loss, trouble moving the legs and pain.
Wernicke-Korsakoff Syndrome-alcoholics, malabsorption, anorexia
www.mayoclinic.org/drugs-suppl...
www.mayoclinic.org/drugs-suppl...
ods.od.nih.gov/factsheets/Thi...
lpi.oregonstate.edu/mic/vitami...
umm.edu/health/medical/altmed/...
www.ncbi.nlm.nih.gov/books/NBK...
pubmed.ncbi.nlm.nih.gov/22116...
www.mdpi.com/2073-4409/10/10/...
www.researchgate.net/figure/B...
pubmed.ncbi.nlm.nih.gov/15328...
Dr. Jin Sung is a Chiropractic Physician who specializes in the management of complex chronic conditions in Massachusetts, 30 minutes north of Boston. He utilizes natural and alternative therapies to help manage complex cases such as Hashimoto's, autoimmune conditions, IBS, SIBO, chronic fatigue, brain fog, early Alzheimer's, etc.
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1. Thiamine HCL
2. Benfotiamine
us.fullscript.com/catalog/pro...
us.fullscript.com/catalog/pro...
3.TTFD- thiamine tetrahydrofurfuryl disulfide us.fullscript.com/catalog/pro...
4. Nutritional yeast us.fullscript.com/catalog/pro...
Dr. Sung's Online Supplement Dispensary-conditions apply. Certain companies will require a prescription from Dr. Sung.
The content of this video is for educational purposes only and does not constitute medical advice. Please consult with your physician before embarking on any dietary changes or taking any nutritional supplements.
40 year retired ICU nurse here. We always gave IV thiamine to our heavy alcohol drinker patients.
Yes and a load of petrol made drugs on top of that 😂
@graciejohnson52 Thank you for saying that. I'm going to show your comment to a friend of mine who keeps drinking whiskey despite the fact that she just had 1 kidney and her pancreas removed and is diabetic! She doesn't believe in "vitamin mumbo-jumbo". Your comment lends credibility here. Thanks also for your service. Nurses do the heavy lifting--especially ICU.❤
Looking forward to part 2. Great video!
Last summer was suffering from confusion and brain fog. Was recommended to try B1 100 MG daily. After taking the first dose in morning by afternoon symptoms were gone. It was like a switch was thrown. Been taking it ever since and have not had any reoccurring events.
Which form of B1 did you take?
@@marioa9350 Nature Made B1 100mg
@@johnletourneau6176 appreciate the feedback
Placebo is a powerful stuff
@@MrDarre86 bro shutup
I love your informative videos, Dr. Sung. Thank you!
Wow, great information Dr!!! Brilliant doctor! Thank you so much for all of your videos ❤
Dr. Jin W. Sung
First time listener, instant subscriber! Many thanks for the information, and your delivery of it without gimmicks.
When consuming NAC, it must also be partnered with thiamine to assure production of higher amounts of glutathione.
Thank you, sooo interesting! 🐘🦒🐆🦁
👍
thanks!
Thiamine and magnesium together make glutathione.
Thank you so much!!❤❤❤
Thank you Doctor Sung. Very interesting.
Always so interesting. Ty
no doctor wants to address the dsub-clinical symptoms, whereas the patients live a miserable life because of those symptoms.
Yes please Cover this vitamin I'm too sick to read Derek's work
Welcome back to Dr. Clapper. Anyway thanks good video.
B1 must add POTASSIUM, MAGNESIUM sice can deplete ELECTROLYTES
You are 100% correct!
With So many problems folks are facing with small intestines I would think B1 deficiency is much more common than you mentioned. Example; Celiac tears up the small intestines
Yes about 75% of GI issues are due to GMO garbage from farmers playing with the crops and spraying them with pesticides and plus food these days is void of nutrients so it's a culmination of nutrient deficiencies and the body rejecting GMO fake food. The other 25% is due to genetic predisposition.
I absolutely agree.
Mostly goes undiagnosed by doctors. People end up dead or nearly dying with irreparable damage before they figure it out. Thanks to the endless information of the internet, the "layman" knows more than some doctors these days.
I never thought of that. I don't have celiac disease but I have gluten and GI issues and cannot tolerate any gluten and most other grains, as well as other food allergies.
@@lindam9618 Me too. Dairy bothers me, as well. Do you suffer from constipation or insomnia (my issues).
Had issues with my left eye being suppressed for years. All the daily exercises only helped for a few minutes. A lot of chronic tension on the right side of my body.
Bought some quality B1 from a good brand and was astounded, that the next day my left eye started focusing again and giving me back my depth of field. Just a small thing like that had a huge impact
What brand do you take, if you don't mind sharing?
@@lindam9618 i usually buy sunday natural products, if they have what I need. In this case I did as well.
Amazing
Whaat!!?What!!?? Wow thank you for commenting.. I have left eye suppression and it's amblyopia or strabismus.. I have double vision now. Just got B1 by Nutricost . What brand did you get? Also how is your vision now?
@@ShinySilverBunny i do exercise on a weekly basis for amblyopia and take the B1 from sunday natural.
I actually answered to lindam who had the same question, but somehow that comment is gone.
Thanks so much! Love your videos!!!
Thank you Dr Jin Sung, very useful information
Food based organic b complex
Thank you very much Sir!!
Do you have any suggestion on when to supplement and when to get an IV? How low/at what level? And THANK YOU VERY MICH FOR A CONCISE BUT SPOT ON DISCUSSION!❤
Very useful information. My level of B1 is 3.65 ng/ml. I take supplements
We need more information on the subject.
B1 got rid of my anxiety. I take it with a b complex. Works great. B1 plus a B complex!
Hi, what brands of b1 and b complex do you take ? Please help 🙏
@AJE which brands and dosages worked to help with your anxiety? Thanks.
All the excess vitamins went to his brain and killed him. Rip wahopin.... rip
@@browneyedgirlFL67 Do your research and just pick a good brand. I use several different ones plus nutritional yeast.
@@NOT-WOKE-007 how often do you use Nutritional yeast?? Do you need to take them togther??
Thank you
What you mentioned at start, is what exactly happened with me. Now, I am regularly taking b1 tablet
Well, I haven't listened to the entire video yet, but I have been looking into this. I am thinking this subclinical "deficiency" is highly correlated to the COVID brain fog issue. Stress and infection deplete Thiamine, hence brain fog etc. Optimal Thiamine is not the same as an amount that masks clear symptoms. I even give my potted.plants thiamine.
Interesting. Didn't know about the stress and infection link to B-1. Thanks!
So you can have autonomic system symptoms with both wet and dry beri beri?
What if your Thiamine is high is it cause for alarm? Great video
Why is synthetic forms of Vit B1 all we can find?
Dr.Jin
Are you doing part 2 on the Befotaimine the fat soluble B1?
I will.. been busy playing Xbox
B1 got rid of my restless leg syndrome! Try taking it daily! Be sure to take it with a B Complex tablet.
what dosage worked for you?
@@jasongendron8309 I take Benfotiamine 300mg daily.
@@NOT-WOKE-007 thanks
Thank you. Sometimes you learn just as much from the comments as you do from the video!
@@NOT-WOKE-007 How long were you taking it before you noticed that?
i will try it .and then i will get back to you .the was very help full .thank you
How did you go?
I was having acid reflux due to thiamine deficiency. A multivitamin wasn't adequate to take care of it either. I had to use a b1 supplement. Taking it solved my acid reflux that same night. Not sure how I got that deficiency to begin with.
How many milligrams? Would 250 be okay?
By age naturally you get it. Secondlyhigh carb diet
Interesting that a deficiency mimics autonomic symptoms.
🤯🤔‼️
Look at this video too ua-cam.com/video/GlpXUIQWBok/v-deo.html and this ua-cam.com/video/rjVXFqiPDwE/v-deo.html
It doesn’t mimic them, it causes them! B vitamins are crucial for Nervous System support & repair. All of them, but particularly B1 & B12. So many of our modern diseases are just due to undiagnosed Thiamine deficiency, particularly anything with Nervous System involvement. And it is no coincidence that most, if not all of the CV & long-haul symptoms mirror those of Thiamine deficiency, either…….
It does not MIMIC, it IS THE ROOT CAUSE of autonomic outcomes!
My blood test came back as 295 nmol/l… is that too high & I should stop taking benfotiamine?
I just started takwing B1 thiamine, wow! What a difference! But seems like i got grouchy 😢😢
Can Vitamin b1 help for left atrial enlargement
I start feeling like my nervous system is glitchy and sparky. Panic feeling and dizzy spells. Chest pain and heart arrhythmia. No appetite. Nausea. Basically feels like you're gonna die soon.
Try a functional medicine doctor. You'd be surprised what they can do with hormones and vitamins.... even testosterone! But suggest you start with Nutritional Yeast Flakes and Benfotiamine on Dr. Sung's schedule... every 12 hours!!
Same problem
At 1:00 you gives a quote that made me think. Maybe it is the thiamine deficiency due to impaired apsorbtion caused by excess alcohol consumption that is making alcoholics thin in the last stages? Because they do get excess calories from the alcohol, and of course they lack fatty acids and amino acids in their diets, but maybe they cannot utilise them even when they get some? Just wondering about this. Haven't read the literature.
This makes a whole lot of sense!
Y
Small Ulcer will cause gut issues and nutrition deficiency...so root cause is stomach issues....supplement b1 will help but you got to to root cause
Holy (bleep)! I have learned some of the wonders of B1 and it has already changed my life... but... "every 12-hours" I didn't know. I take an expensive brand of nutritional yeast flakes and at first I thought "don't take too much, it costs a lot." Now I am doubling that. Also taking Benfotiamine too. Thanks doc. I do rely on your videos.
When you discover allithiamine your world will change. The fat soluble form of b1. It will charge your depleted b1 so quick especially in alcoholics. It is in all of the onion family.
And not synthetic like bento
@@Lsvdp369Dr. Berg stated yes Benfotiamine is synthetic, but he's never found any negative issues with it.
Can one get both dry beri beri symptoms and wet beriberi symptoms in the body?
Yes.
Trying to recuperate and reintroduce B1 back into my system after taking metronidazole & suffering toxicity from its side effects.
Very informative information, thank you!
That's nasty stuff, so many prescription drugs deplete the body and cause mitochondrial dysfunction.
what does Thiamine deplete though? i remember reading that it does deplete something else in the body so its important to always take it with that. Wish i had saved that info somewhere because its not easy to google. I'm sure one of the things was selenium.
Vitamin B2 and Mg. Another UA-camr (might have been Elliot Overton) mentioned that increasing vitamin B1 consumption causes increased utilization of vitamin B2 and magnesium, which necessitates taking them with high-dose vitamin B1 in order to avoid certain negative effects and enable vitamin B1 to carry out many of its functions.
I found it, this is the comment: " B1 increases demand for B2, but adding B2 may not do anything if there is an underlying iodine, selenium, and/or molybdenum deficiency. As most are iodine deficient and unaware of it, adding iodine-iodide such as Iodoral can be extremely helpful. Very important to check into this, as iodine (as well as selenium and molybdenum) is necessary to activate B2. A B1 therapy "crash" can be avoided or fixed by having enough of these other important cofactors."
Surgeries
Bad diet
Alcohol
Cigarettes
Diseases
Infections
Stress
Chronic stress
Traumas
Coffee
Root canals
Amalgam fillings
Other toxic agents used in dentistry
Inplants= surgery
Co2 poisoning
Accidents
Illnesses
Molds
House hold chemicals
Glysphosphate
Antibiotics
Pregnancies
Abortions
Positive stress too, because stress causes depletion
Methylation problems
Cooking for to long, sepleting nutrients
Poor soil quality to grow fruits/vegs
Crap/poor diets of animals for meat
Medication
Psychiatric medication
Vaccinations
The list goes on...
POTASSIUM, MAGNESIUM.
Since can deplete ELECTROLYTES
Significant and/or prolonged doses of quercetin, rutin and bioflavonoids in general can decrease thiamine levels
Damn it, that clap in my headphones damaged my eardrum, I'm going to need the name of your malpractice insurance provider, what state are concurrently practicing medicine in?
💙🌀 💫 🌀💙
Dr: Derrick
Lonsdale
💙Thanks💙
We miss you
💙🌀💙🌀💙
What about high doses everyday of thiamine in Parkinson's disease?
An Italian doctor used this indeed with sucess, but he died recently.
Also for essential tremor.
Dr. Coimbra ( Brazilian neurologist ) uses high vitamin D for curing parkinson.
See the Coimbra protocol.
I’ve seen videos that it greatly helps
It’s been shown to help a great deal. Some people have been able to reverse this condition. I am really excited about this because it can even help folks described as having Parkinsonism. Not full on Parkinson’s and not much is really known about it but when people present with these symptoms and test negative for Parkinson’s they just call it Parkinsonism.
“your body will fail.” Hit me like a ton of bricks.
This is pretty much me, I've been losing weight for the last 3 years despite eating well, down to 56kgs/124lbs from 74kgs/167lbs!!! Not digesting or absorbing, looks like B1 is a factor! Tried Benfothiame 100-200mg per day before, but need high doses up to 1000mg to get body working again. Also will take Magnesium & Potassium.
I just checked my vitamin B1 through blood test and my B1 was high
Make sure you take magnesium with B1 they are cofactors
It’s the T in the M A T H + protocols for Covid19
@Tammy Maher What does the rest of MATH stand for? Thank you.
@@browneyedgirlFL67 The MATH+ protocol was created to treat patients in hospital and intensive care units, based on using therapies such as anti-inflammatory corticosteroids (Methylprednisolone), high-dose intravenous Vitamin C (Ascorbic acid), Vitamin B1 (Thiamine), and an anticoagulant (Heparin), plus co-interventions such as antivirals and supplements (MATH+)
O
I use iv b1 . I have to get it of E bay because doctors are assholes
Ho-weh-wo = however
😂😂