Berberine: Type 2 Diabetes Game Changer

Поділитися
Вставка
  • Опубліковано 29 вер 2024
  • Berberine Helps Release Insulin From Pancreas
    Berberine is a magical molecule with a vast array of effects. Today we will focus on the mechanism of insulin release and the impact of Berberine on the pancreatic beta cells.
    If you like this content and want more, I am doing a special lifetime membership offer. Click here:
    www.drbeen.com...
    Want to support this work?:
    Buy me a coffee :-) www.buymeacoff...
    Become my patron: www.patreon.co...
    PayPal: paypal.me/mobe...
    My substack: mobeensyedmd.s...
    #drbeen #koolbeens #Nutrition
    Disclaimer:
    This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
    Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
    References:
    Frontiers | Glucose-lowering effect of berberine on type 2 diabetes: A systematic review and meta-analysis
    www.frontiersi...
    ATP-sensitive K+ channels in pancreatic beta-cells. Spare-channel hypothesis - PubMed
    pubmed.ncbi.nl...

КОМЕНТАРІ • 128

  • @atrumluminarium
    @atrumluminarium Рік тому +8

    Would be nice to see a Metformin vs Berberine deep dive as a future lecture

    • @cindypendleton7901
      @cindypendleton7901 Рік тому +1

      My husband is allergic to metformin. He does great in berberine.

    • @pamwaldron3504
      @pamwaldron3504 4 місяці тому

      Why don't pharmacists and doctors warn you that networking reduces one of the B vitamins over time to the point you will become so deficient you will die?
      I consider that to be negligence at best and attempted murder at worst.
      If you take Metformin, supplement your B vitamins from the beginning if you'd rather live and be healthy.

  • @terfalicious
    @terfalicious Рік тому +2

    Love the obligatory cat tail passing by! 😻Love to Kyrie!

  • @fijyify
    @fijyify Рік тому +31

    I read this randomized controlled study "Effect of berberine administration on metabolic syndrome, insulin sensitivity, and insulin secretion" that showed that"Administration of berberine leads to remission of metabolic syndrome and decreases in waist circumference, SBP, triglycerides, and total insulin secretion, with an increase in insulin sensitivity". So, it appears that berberine doesn't increase insulin secretion. Another study showed that "Berberine induces GLP-1 secretion through activation of bitter taste receptor pathways".

    • @billytheweasel
      @billytheweasel Рік тому +2

      Study titles much appreciated!

    • @HerbalAmandaL
      @HerbalAmandaL Рік тому +1

      @@billytheweasel I believe the title is the 1st part of the statement in Quotation 😀

    • @HerbalAmandaL
      @HerbalAmandaL Рік тому +3

      Your quote says "with an increase in insulin sensitivity" but then you state that it doesn't - I'm confused 🤔

    • @billytheweasel
      @billytheweasel Рік тому

      @@HerbalAmandaL yep and I really appreciate that!

    • @BCSTS
      @BCSTS Рік тому

      @@HerbalAmandaL I think you should read his/her comment again....maybe find & peruse the study referred to....I do not see where there is a contradiction....

  • @sheilahendrix5935
    @sheilahendrix5935 Рік тому +1

    May 💚God💛 Be ❤️With 💜Everyone💛 Always❤️ Much 💜Love Blessings 💛Always ☺️ ✌️✌️🎇🌈🌐💜❤️💛💛💚💙💙💚💚💛❤️💜💜

  • @bobthrasher8226
    @bobthrasher8226 Рік тому +2

    I hope Dr Been will look into high-dose Thiamine - see the book "Thiamine Deficiency Disease, Dysautonomia, and High Calorie Malnutrition" - may provide help to long haulers and many other conditions.

    • @christineknapp-phillips
      @christineknapp-phillips Рік тому +1

      Yes! Dr. Lonsdale book is amazing! Research and presentations by Lonsdale, Constantino, Marrs, Overton has been so helpful.

    • @bobthrasher8226
      @bobthrasher8226 Рік тому

      @@christineknapp-phillips Glad you found them. I know Dr Been has covered thiamine but I don't think he or Dr Marik appreciate high-dose vitamin therapy yet.

  • @dwdwone
    @dwdwone Рік тому +1

    This sounds very similar to how sulfonylurea drugs like glypizides work in the pancreas in that the calcium channels are manipulated by a change in polarity. Is it the same kind of mechanism but in the liver?

  • @jovoorheescollinsmphbsnbch6245
    @jovoorheescollinsmphbsnbch6245 Рік тому +17

    Thank you so much for this lecture Dr. Been!!
    I am a diabetes management coach and i
    I have shared this video with my diabetes support groups totaling 90K viewers 😁 this is going to be so helpful for them!!!

  • @sherrystouth7707
    @sherrystouth7707 Рік тому +14

    I tested as prediabetic twice in 2021 and my dr just dismissed that i had all the symptoms of insulin resistance, so i began taking bererine on my own (since i wasnt put on any pharmas to help) and its helped a lot.

    • @ssss-xt3dk
      @ssss-xt3dk 7 місяців тому

      Can you please tell what is your current situation

    • @melznutz3313
      @melznutz3313 4 місяці тому

      Cannot out exercise a bad diet. Stop eating bread and drinking sugar water now and ur halfway there!
      Take a lil time with the rest and make the changes permanent. Cheers 🌞

  • @t.hunter4660
    @t.hunter4660 Рік тому +21

    My mother has been taking Berberine for a few years to help with her cholesterol levels. I am really looking forward to hearing the rest of this series. Thank you so much Dr Been!!!

    • @terfalicious
      @terfalicious Рік тому

      How is it working for your mother?

    • @jovoorheescollinsmphbsnbch6245
      @jovoorheescollinsmphbsnbch6245 Рік тому +1

      Have you noticed it has helped her?

    • @mygundidntdoit999
      @mygundidntdoit999 Рік тому +3

      You might have your mother's iron levels checked while she's on Berberine, because I read where it chelates the iron. I became anemic and figured out Berberine was contributing to it. Other things that I've found which work just as good are Bitter Melon and Amla.

    • @terfalicious
      @terfalicious Рік тому

      @@mygundidntdoit999 Thanks - I have ongoing problems with anemia, and this info is appreciated!

  • @johnsnider2006
    @johnsnider2006 Рік тому +11

    As an antibiotic it is a mild antibiotic, but the value in it is it destroys the biofilm making other antibiotics more effective

  • @bobchannell3553
    @bobchannell3553 Рік тому +6

    Very good talk. I understand. Thanks for the video. Since I have type two diabetes, I'll try to watch all of the videos in this series.

  • @nipagandhi7251
    @nipagandhi7251 Рік тому +8

    You are such a Great Teacher 👍👍👍

  • @MamaRestInPeace1424
    @MamaRestInPeace1424 Рік тому +7

    Dr Been you are a truly wonderful Researcher and Doctor. Your help to humanity is beyond words. Thank You!

  • @johnsnider2006
    @johnsnider2006 Рік тому +24

    If you mix it with Metformin there is a synergist effect, especially if mixed with tummeric and sage, and can lower blood sugar very low. It also becomes cardiotoxic if mixed with statins.

  • @annalisette5897
    @annalisette5897 Рік тому +7

    This is a big surprise! Berberine occurs in Mahonia aquifolium, Oregon's state flower the Oregon grape. Native Americans used parts of the plant medicinally but those parts of the plants have been considered to be fairly toxic. The berries are edible but generally unpleasant. The roots bleed yellow when dug up. Roots, bark and berries can be used to make a variety of dyes ranging from yellow to purple.

    • @barbaraseville4139
      @barbaraseville4139 10 місяців тому

      The ripe berries make very tasty jam.

    • @barbaraseville4139
      @barbaraseville4139 5 місяців тому

      Ripe berries make a delicious jam. Recipes are on line.😊

  • @jeffreyscottfishman
    @jeffreyscottfishman Рік тому +7

    Im worried about Berberine lowering blood pressure. What if you already have low blood pressure? Will it make it worse?

  • @brenda126176
    @brenda126176 Рік тому +7

    I am so impressed with you!!! Joining your channel today, God willing!

  • @breathless8075
    @breathless8075 Рік тому +5

    I have just found your channel and I I have type 2 Diabetes. I am always interested in what I can do to continue working on my diagnosis. It's really changed my way of life and has made it not too fun. So much that we do traditionally involves food, when we gather with friends and family. I don't know much about Diabetes but I want to learn. Thanks so much for this lesson. Could be life changing.

  • @leifkring6346
    @leifkring6346 Рік тому +3

    I've been searching for natural compounds which can reduce glutamine. So far I've only found two, of which berberine is one.
    Cancer cells use glucose as fuel, so by a ketogenic diet you can minimize the glucose levels and this can be enough to kill some cancers. But if the cancer cells don't have access to glucose, they will use glutamine as fuel.
    There are some glutamine-blocking drugs, e.g. 6-diazo-5-oxo-norleucine (DON), but they are not available. They also have some bad side effects.
    Theanine is the other natural compund that can have a glutamine-reducing effect, as it inhibits the glutamine transporter.
    Can anyone suggest some other glutamine-inhibiting natural compounds?

  • @sheilahendrix5935
    @sheilahendrix5935 Рік тому +1

    Peace💛 and 💚Blessings❤️ Too 💙My💜 Brother 💚May❤️ God💙 Bless 💛You 💚Always ❤️May 💙God💛 Bless 💚You ❤️Richly💙 with Everything💚 You ❤️need💙 Always Much💛 Love 💚Blessings💙 Always ☺️ 🎇🌈🌐✌️💯💛💚❤️❤️❤️❤️💚💚❤️❤️❤️❤️

  • @PeterQuentercrimsonbamboo
    @PeterQuentercrimsonbamboo Рік тому +4

    Well… we have been using plant medicines that contain berberine for decades in natural health practice for benefiting such conditions -

  • @margaretmacinnes1519
    @margaretmacinnes1519 Рік тому +7

    Thank You Dr Mobeen and all
    The Koolbeens!!! Great lecture to begin the study of Berberine♥️♥️♥️ wishing all a good night 😴💤🌙 😄🙏

  • @delarrubio
    @delarrubio Рік тому +2

    The berberine effect that blocks the clearing of potassium, and as a result, calcium receptor channels opening up, does it mean you should avoid taking berberine if you are taking ACE inhibitors(ramipril) and calcium channel blockers like amlodipine? Or, does lowering the dose of ACE and/or CCB can work in tandem with BBRN? Thanks for your very detailed illustrations Dr.!

  • @headybrew
    @headybrew 4 місяці тому

    How do the K+ ions get into the cell? Perhaps I missed that... Thanks for you great video explaining beta cell function.

  • @moneymattersforeverybody
    @moneymattersforeverybody Рік тому +3

    I really appreciate your lectures. Have been praying about joining for some time and finally today, took the plunge. $67 for lifetime access is a no brainer! Thank you! ~Terri

  • @mygundidntdoit999
    @mygundidntdoit999 Рік тому +4

    Thanks for the great video. I have pre diabetes and have used Berberine, and it works. The only side effects I've seen are constipation and it lowers iron. I became anemic and figured out Berberine was contributing to it. I still take Berberine every once in a while, but use bitter melon, amla and other things most of the time.

    • @2bbossfree
      @2bbossfree Рік тому

      I have not seen a lowering of my iron....I cook with an iron skillet. Think that has anything to do with it? I have pre diabetes, high cholesterol and macular degeneration, so happy with the supplement.

  • @katl6320
    @katl6320 4 місяці тому

    are there any side effects of berberine? i am hypoglycemic (self diagnosed)

  • @marantz747
    @marantz747 3 місяці тому

    How long is berberine effective in a diabetic? Does it become less effective after 5 or 10 years?

  • @FightBackAgainstDiabetes
    @FightBackAgainstDiabetes 9 місяців тому +1

    *You Did Not Choose To Be Classified As Diabetic, But You Can Choose To Fight Back Against Diabetes* 💪

  • @mrsrichter8586
    @mrsrichter8586 Рік тому +1

    I am even more confused now - there is berberine from the berries, called barberry. And there's berberine from the bark of the plant and berberine from the roots of the plant all sold seperately as berberine. Whyyyy??? What's the difference and why must everything be so complicated and confusing?

  • @MakaiMauka
    @MakaiMauka Рік тому +1

    My wife was taking 24 unit of insulin daily. Now takes 4 units of insulin daily after starting Berberine 500mg twice daily.
    Promises she did nothing else differently. Quite amazing.

  • @FahlstromJohn
    @FahlstromJohn 9 місяців тому

    will Berberine cause elevated fasting insulin?

  • @9111logic
    @9111logic Рік тому +2

    Sorry I could not follow you live from the UK - Marvellous explanation, perfectly understandable, thank you so very much again our dearest Mobeen 🙏🥰

  • @diana12701
    @diana12701 Рік тому +1

    I have a question I started taking barberine and I get really bad bloated want to not give up 😕on the barberine. any advise in how I can prevent the bloated from happening 🙏thank you Dr.Mobeen p.s love your drawings 👍

  • @vickiredfeather4808
    @vickiredfeather4808 Рік тому +1

    Been using for years. Would like to know best brand

  • @terfalicious
    @terfalicious Рік тому +1

    Very excited for the series. Especially interested on effects on the kidney, as I have had problems (genetic predisposition to PCKD). Also wondering about Vit D effects on kidney - I've read conflicting info. THANK YOU Dr Been!

  • @billytheweasel
    @billytheweasel Рік тому +1

    Great reminder. I ran out of berberine before we moved from America.

  • @patriciamuscat1049
    @patriciamuscat1049 10 місяців тому

    Thank you for your lectures Im a patient with heart failure and Im on medication Entresto, Jardiance, spironolactone, nebivolol, and rivaxoban. can we take it ?

  • @tinyspeckofdust37
    @tinyspeckofdust37 8 місяців тому

    This explanation is fantastic ! Dr Been would you be kind enough to do the same with thyroid hormones and all the connections including Reverse T3 and perhaps highlight the most important natural treatment eg. A supplement or a beneficial herb please? And if you could discuss Adrenal exhaustion and what can be helpful based on your research? That would be very much appreciated 💕 thank you. Ps. I have been taking Berberine for around 2 months.

  • @upriver7047
    @upriver7047 Рік тому

    Thank You! Your explanation was very helpful. Do you think Berberine with the addition of cinnamon or milk thistle would be helpful to better absorption of the berberine? Or is it better to just increase the dosage of berberine? I'm subscribing to learn more from you. I appreciate your efforts to educate the general population.

  • @rimavanhill-seal7557
    @rimavanhill-seal7557 Рік тому +3

    I missed it

  • @bilel1299
    @bilel1299 Рік тому

    I used to be type 1 here, but I'm now out of control owing to a terrible diet. Carbohydrate diets are easier to follow. I was forced to use the gluconize brand. check if it works

  • @zbyszek2951
    @zbyszek2951 Рік тому

    Other medicines increasing production of insulin can cause hypoglycemia due to continue of work at low level of glucose. What is difference? does it means that they are closing one or both channels more tightly or open Ca++ to let insulin out?

  • @dwightcarlson7136
    @dwightcarlson7136 Рік тому

    Would like to hear whether taking Berberine with Metformin is good, bad or indifferent????

  • @randyromines7364
    @randyromines7364 Рік тому

    I have non-insulin required blood sugar to manage. My injectable has become unavailable due to supply issues etc. This sounds like the perfect thing to start taking to help control sugar levels. Funny thing is when I could no longer use the injectible I suddenly dropped 14 lb in less than 2 months and have not gained it back.

  • @lindapestridge3073
    @lindapestridge3073 Рік тому

    Dr would you do a video
    On bergamot please.

  • @denachubbic9494
    @denachubbic9494 Рік тому +1

    Thanks to your teaching I understand what berberine does. But how does berberine do it? How does it close the less active potassium channel?

    • @dwdwone
      @dwdwone Рік тому

      I'm not sure but I think it changes the polarity due to its natural structure.

    • @DrBeenMedicalLectures
      @DrBeenMedicalLectures  Рік тому +1

      It binds to these channels.

  • @halifaxlithos2488
    @halifaxlithos2488 Рік тому

    I always learn from your presentations, Dr. Mobeen. As an added benefit, I find them enjoyable.
    I look forward to seeing more of you and your cat in the future.

  • @glenndavis4452
    @glenndavis4452 Рік тому

    Have heard this from other medical discussions.
    They recommended it with circumin

  • @amywjn
    @amywjn Рік тому

    Thank you for going over the studies & being to thorough & unbiased.

  • @seanvogel8067
    @seanvogel8067 Рік тому +1

    Thanks!

  • @Optimization_Coach
    @Optimization_Coach Рік тому

    Do we have a good comparison vs Metformin ??

  • @pettutor4213
    @pettutor4213 Рік тому

    Does increasing insulin with this mechanism also risk increasing insulin resistance? I would think we want to increase insulin sensivity and not increase total insulin. Great lecture I joined your lifetime membership program.

  • @HappyLife-wv5ms
    @HappyLife-wv5ms Рік тому

    Is there an increase in intestinal infections with long term use of berberine?

  • @dorotap9423
    @dorotap9423 Рік тому

    Can berberine be used long term?

  • @KathyCreed-dj3fn
    @KathyCreed-dj3fn Рік тому

    Thanks!

  • @DaisyIdes
    @DaisyIdes Рік тому +12

    Thank you for this one. I just recently purchased Berberine for this purpose. My numbers are not terrible, but I am a smidge above normal.
    I also saw studies showing berberine may be effective in helping with dementia (diabetes 3). My mother died of Alzheimer’s, so this is also of import to me and my family.

  • @lisashapiro4714
    @lisashapiro4714 Рік тому

    This is terrific

  • @kayemoore
    @kayemoore Рік тому

    Very clear, super helpful!

  • @jeffrey4577
    @jeffrey4577 Рік тому

    Outstanding

  • @HerbalAmandaL
    @HerbalAmandaL Рік тому +1

    It is my opinion that it much better to use the plants rather than the supplement. This is why turmeric is one of my favorite herbs for my diabetic clients with fenugreek ❤️

    • @HerbalAmandaL
      @HerbalAmandaL Рік тому

      Same for cardiovascular and even autoimmune

    • @jayajora
      @jayajora Рік тому

      Huh? Not in India

    • @HerbalAmandaL
      @HerbalAmandaL Рік тому

      @@jayajora what do you mean, "not in India."??

    • @jayajora
      @jayajora Рік тому +1

      @@HerbalAmandaL turmeric is part if their everyday use yet diabetes out of control

    • @HerbalAmandaL
      @HerbalAmandaL Рік тому +1

      @@jayajora oh, I see now what you meant. Eating it as a spice and using it medicinally are 2 different things. You can also use other herbs, berberine is the chemical found in them. Using the whole plant as medicine provides better synergy than just 1 chemical. 😀

  • @2bbossfree
    @2bbossfree Рік тому

    Earl gray tea has berberine and Stack makes a high berberine teabag.
    It is in a citrus fruit used in Italy and some think this might be part of the reason why the Mediterranean diet was thought to be so good, along with olive oil instead of canola oil. Without the berberine, the Mediterranean diet is very different.

    • @n.a.1397
      @n.a.1397 Місяць тому

      Ordinary Early Grey tea is just bergamout added to black tea, no? It doesn't have berberine? Wht is STack?

  • @aliyamea
    @aliyamea Рік тому

    Another good show!!

  • @sandrajones2926
    @sandrajones2926 Рік тому

    nice art

  • @TheRolandSmith
    @TheRolandSmith Рік тому

    Thanks!

  • @JJ-hg5ho
    @JJ-hg5ho Рік тому

    🙏

  • @mehtabbandesha5637
    @mehtabbandesha5637 Рік тому

    awesome

  • @AlimaElysee
    @AlimaElysee Рік тому +3

    A loved one was taken off his diabetic and hypertension meds after hospitalization last month for AKI subsequent to a bout with the virus. Thankfully, his readings have been excellent without them. Our physician recently approved adding berberine and quercetin/bromelain for nutritional support. It is reassuring to learn how effective berberine is especially with kidney function. Thank you, Dr. Been for your untiring, diligent research and dedication to disseminating this vital knowledge.

  • @johnreas9216
    @johnreas9216 Рік тому

    Illustrated to perfection!!….I’m hereby dubbing Dr.Been not only as his rightfully deserved KingBeen, but also as: ‘Picasso-Been’.🧐

  • @babayaga5225
    @babayaga5225 Рік тому

    I got to be honest. I felt really uncomfortable when at the 6 minute mark you mentioned, "it has the potential to treat some cancers". There should be a BIG disclaimer there.

    • @scotmil1
      @scotmil1 Рік тому +2

      So you are cool talking about diabetes, but mentioning a potential in treating some cancers is taboo? He wrote "Anti tumor effect." I am sure you are going to make it through this emotional setback.

  • @dwightcarlson7136
    @dwightcarlson7136 Рік тому

    I believe bananas have quite a bit of potassium. Therefore is it good to eat bananas to reduce A1C?

    • @FahlstromJohn
      @FahlstromJohn 9 місяців тому

      many report very high glucose numbers after eating banana...might be better to get potassium from other sources

  • @babayaga5225
    @babayaga5225 Рік тому

    I got to be honest. I felt really uncomfortable when at the 6 minute mark you mentioned, "it has the potential to treat some cancers". There should be a BIG disclaimer there.

    • @terfalicious
      @terfalicious Рік тому +2

      "Potential to" IS a disclaimer - same as saying "MAY/MIGHT" do something, not that it absolutely "DOES" do something. Even in studies that show efficacy and/or causality, individual results MAY vary.

    • @setapart27
      @setapart27 Рік тому

      ​@@terfalicious I hope you investigate the poisonous poke also..😢

    • @terfalicious
      @terfalicious Рік тому +1

      @@setapart27 I stay far, far away from crazy-eyed people with coming at me with needles - especially those sent by the gov't or captured corporations; I read my George Orwell back in the day!