Oral azacitidine maintenance in AML with MDS-related changes: insights from QUAZAR AML-001

Maria Teresa Voso, MD, University Tor Vergata, Rome, Italy, discusses a sub-analysis of the QUAZAR AML-001 (NCT01757535) study, which examined oral azacitidine maintenance therapy for patients with acute myeloid leukemia (AML) with myelodysplastic syndrome (MDS)-related changes. The study found that azacitidine significantly improved relapse-free survival (RFS) compared to placebo, suggesting it may effectively prolong survival and achieve measurable residual disease (MRD) negativity in this high-risk group. This interview took place at the 29th Congress of the European Hematology Association (EHA) in Madrid, Spain.
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