My college roommate passed away due complications while battling (ALL) 4 years ago. He was a 29 year old profession game developer (Married). Thank you for spreading awareness and I hope one day it can be more effectively treated. R.I.P. Chris I miss you friend
I've been waiting for this topic for a long moment thanks from the bottom of my heart Zach, we need more from Lymphoma. Thanks again for your work we love you 💖💖💖
I am 25 yrs old and have B-ALL myself. At the moment I am in the maintanance part of the treatment. All I can say is that it is such a horrible journey but there is no choice. The video is really in-depth and helps to understand in a lot of detail
My mum has it, aged 74. She was in hospital for a month, then stayed at my sisters place for a couple of days and yesterday was readmitted due to high temperature and fever. I visited her today and she was exhausted and unable to concentrate. Her temperature has lowered towards normal. She is in a study program instead of receiving regular chemo. She is pumped with a chemical 24 hours a day via a pick in her arm. She is in the hospital where she began nursing and says she finds it interesting to be a patient there. She is the only human in the world who matters to me. Overpopulation of immature white blood cells is something I never imagined would be something I cared about. The medical expertise displayed by the video maker here is staggering. Unbelievable brain power to remember and understand all that.
@@realreal5745 I think she and my sister use the term ‘bling’. In the last few days she’s found it very hard to construct a sentence and she was eating pills from the wrong days of the week when she was staying at my sisters house. She’s been readmitted to hospital where the night staff are apparently mean. She had already been in a ward for a whole month before she was discharged so I think she liked being at my sister’s house. They have emergency stopped giving her 24 hour bling. I don’t know what the next step is. Hopefully this chemobrain will reduce. I’ve never seen her like this before. Despite the MRI coffins, the lumbar punctures and the marrow biopsies, she has not experienced pain or complained (except about the hospital night staff). When I visited her ward, the endless beeping and people coming in and out all the time seemed infuriating. It appeared that hospital schedules are non existent and no departments speak to one another. Also the alarms going off all over the place seem to beep right beside the patient’s face when a fluid runs out, and it can take an hour or more before a nurse checks it. I pressed the call button once and it took an hour for them to arrive. This seems en par with waiting rooms in emergency, where there is no screen telling the patients what order they are in, despite it clearly being presented on a screen to the triage nurse. Do I really need to conduct a study on the psychological effects of being forced to wait to get laws put in place to punish organisations who keep customers and patients in the dark about how long they have to sit there? It’s just common sense, as is making alerts appear clearly for nurses and admin without disturbing sick patients. As well as bling medication, she’s had some transfusions, and is also being pumped with sodium chloride all the time. She can no longer hold her bladder at all.
Hey zack, love your videos really helped me and my fiancé Dr.Mudaser Amir. Sadly my baby passed way 2 months ago in June due to B-ALL, he really admired you and watched your lectures day and night, he was a really good and kind doctor. I just wanna say thank you on behalf of him. He really enjoyed watching your videos, he often says this zack guy really enjoy learning and teaching others. Kindly pray for him and remember him.
i cant thank you guys enough for this channel. This channel is everything for my studies. You helped me understand the most complicated topics that i cant seem to understand before. Big kudos to ninjanerd team! God bless
I have also watched the videos for Hodgkin’s lymphoma and non-Hodgkins lymphoma today and I just can’t express how much I appreciate you walking through the lymphoblast lines every single time. 😍
Thank you for sharing this info. My husband died of acute leukemia but I never got an explanation from a doctor. The illness was very fast (12 weeks, 5 days). Your videos (certain ones) are helping me make sense of the medical records I requested. I realize your audience is likely mostly medical students, but there may be people like me just trying to understand medical matters because sometimes patients and caregivers work with doctors who are too busy. I only learned what his dx was after his death from the dc. So thanks again for your videos and clear explanation.
Acute Lymphoblastic Leukemia (ALL) is a cancer of the blood and bone marrow that affects the white blood cells. White blood cells fight infection and help protect the body against disease. Bone marrow is the spongy tissue inside bones where blood cells are made. Acute Lymphoblastic Leukemia (ALL) is the most common type of childhood cancer, however it also occurs in adults. It is more common for children to have ALL than adults, however the survival chance is less in adults then in children. The word “Acute” means that the disease usually gets worse quickly if not treated. Acute Lymphoblastic Leukemia (ALL) affects a type of white blood cell called Lymphocytes, which come in 2 main types: B Lymphocytes and T Lymphocytes. ALL may arise from either type of Lymphocyte. Cases of ALL are either known as B Cell or T Cell ALL. B Cell ALL is the most common. Acute Lymphoblastic Leukemia (ALL) causes people to produce too many immature white blood cells. Eventually, these cells crowd out normal white blood cells. Without enough proper white blood cells, the body has a harder time fighting infections. Acute Lymphoblastic Leukemia (ALL) most often occurs in children aged 3-5 and affects slightly more boys than girls. ALL is most common in Hispanic children, followed by those of white and African-American descent. About 3000 people are found to have ALL each year in the United States. Siblings of children with Leukemia have a slightly higher risk of developing ALL, but the rate is still quite low: no more than 1 in 500. Symptoms of Acute Lymphoblastic Leukemia (ALL) Include: -Frequent Infections -Fever -Easy bruising -Bleeding that is hard to stop (Nosebleeds or heavy menstrual periods) -Flat, dark-red skin spots (Petechiae) due to bleeding under the skin -Pain in the bones or joints -Lumps in the neck, underarm, stomach, or groin (These are swollen Lymph Nodes) -Pain or fullness below the ribs -Weakness, fatigue -Paleness -Loss of appetite -Shortness of Breath -Dizziness -Night Sweats -Unexplained weight loss -Anemia Causes of Acute Lymphoblastic Leukemia (ALL): In most cases, the cause of ALL is unknown. Certain inherited syndromes are linked to an increase of ALL, including Down’s Syndrome, Neurofibromatosis Type 1, Bloom Syndrome, Ataxia-telangiectasia, Li-Fraumeni Syndrome, certain forms of Fanconi anemia, Constitutional mismatch repair deficiency, Diamond-blackfan anemia, Familial PAX5 Syndrome, Familial ETV6 Syndrome, and Familial SH2B3 Syndrome. Acute Lymphoblastic Leukemia (ALL) occurs when a bone marrow cell develops changes (mutations) in its genetic material or DNA. Normally, the DNA tells the cell to grow at a set rate and to die at a set time. In Acute Lymphoblastic Leukemia, the mutations tell the bone marrow cell to continue growing and dividing. When this happens, blood cell production becomes out of control. The bone marrow produces immature cells that develop into Leukemic white blood cells called Lymphoblasts. These abnormal cells are unable to function properly, and they can build up and crown out healthy cells. It’s not clear what causes the DNA mutations that can lead to Acute Lymphoblastic Leukemia (ALL). Young children with ALL may have had genetic changes that happened before they were born. ALL in adults is linked to some carcinogens, including tobacco. Environmental risk factors include significant radiation exposure or prior Chemotherapy. Some hypothesize that an abnormal immune response to a common infection may be a trigger.
Explanations was really great. But i think you missed other advanced treatment for ALL like T.cell theraphy. It would be great if you could mention the success rates of these treatment types.
I just got diagnosed with LVH, and I'd like to learn a bit more about it if you have a video on it, or I'd appreciate a video on it. 😊 Thank you for your videos so far.
Damn it took me a week just to grasp tge basic concepts of All and you eluded it all in merely 40 mins. You are a sagaicious Saintvof sorts, please keep uploading these videos ❤❤.
I've been waiting for this topic please help me for explaining other types of leukemia becuase i have exam in th next week thanks alot ninja nerd we love you keep going ,thanks again😍🥰🥰
My head is still spinning because very recently I lost my best friend of the past 50 years plus to Leukaemia. He has always seemed well with no health problems at all. In fact we came back from holiday 4 weeks ago and 2 days later he started getting short of breath. He went into hospital and went down very fast. He died 11 days ago after spending less than 3 weeks in hospital. He was 67 but he's always seemed so fit and healthy.Just how can this happen? Please can anyone tell me, thank you.
I got low lymphocytes 0.72 and found 0.03 blasts in my blood. Now checking t and B cells. The rest of the values looked good. Hoping for the best but am really worried.
My college roommate passed away due complications while battling (ALL) 4 years ago. He was a 29 year old profession game developer (Married). Thank you for spreading awareness and I hope one day it can be more effectively treated.
R.I.P. Chris
I miss you friend
My 17 yo was diagnosed last week, we’re now in st Jude. He has the ALL -B cell😭
My bro diagnose this. Can u tell me the treatment process
@@andleebraja5678 Bone Marrow Transplant. He was in Texas undergoing other experimental treatment
I've been waiting for this topic for a long moment thanks from the bottom of my heart Zach, we need more from Lymphoma.
Thanks again for your work we love you 💖💖💖
I love this! I had ALL as a teen 20 years ago, and it's so awesome to learn about what I went through. Thank you for this!!
Wow
Now you recovered right?
Plz update us if you don’t mind
How old was you when diagnosed
I am 25 yrs old and have B-ALL myself. At the moment I am in the maintanance part of the treatment. All I can say is that it is such a horrible journey but there is no choice. The video is really in-depth and helps to understand in a lot of detail
I hope you heal well ❤️❤️❤️❤️ thank you for sharing your experience
God bless you! Get well soon! ❤
My mum has it too. I hope you get well soon
I am 39 and have B-ALL. Been good since stem cell transplant since 2021. Keep strong and I will be praying for you!
Speedy recovery
My mum has it, aged 74. She was in hospital for a month, then stayed at my sisters place for a couple of days and yesterday was readmitted due to high temperature and fever. I visited her today and she was exhausted and unable to concentrate. Her temperature has lowered towards normal. She is in a study program instead of receiving regular chemo. She is pumped with a chemical 24 hours a day via a pick in her arm. She is in the hospital where she began nursing and says she finds it interesting to be a patient there. She is the only human in the world who matters to me. Overpopulation of immature white blood cells is something I never imagined would be something I cared about. The medical expertise displayed by the video maker here is staggering. Unbelievable brain power to remember and understand all that.
Sorry to hear that. The doctors could be giving her Blinatumomab?
@@realreal5745 I think she and my sister use the term ‘bling’. In the last few days she’s found it very hard to construct a sentence and she was eating pills from the wrong days of the week when she was staying at my sisters house. She’s been readmitted to hospital where the night staff are apparently mean. She had already been in a ward for a whole month before she was discharged so I think she liked being at my sister’s house. They have emergency stopped giving her 24 hour bling. I don’t know what the next step is. Hopefully this chemobrain will reduce. I’ve never seen her like this before. Despite the MRI coffins, the lumbar punctures and the marrow biopsies, she has not experienced pain or complained (except about the hospital night staff). When I visited her ward, the endless beeping and people coming in and out all the time seemed infuriating. It appeared that hospital schedules are non existent and no departments speak to one another. Also the alarms going off all over the place seem to beep right beside the patient’s face when a fluid runs out, and it can take an hour or more before a nurse checks it. I pressed the call button once and it took an hour for them to arrive. This seems en par with waiting rooms in emergency, where there is no screen telling the patients what order they are in, despite it clearly being presented on a screen to the triage nurse. Do I really need to conduct a study on the psychological effects of being forced to wait to get laws put in place to punish organisations who keep customers and patients in the dark about how long they have to sit there? It’s just common sense, as is making alerts appear clearly for nurses and admin without disturbing sick patients. As well as bling medication, she’s had some transfusions, and is also being pumped with sodium chloride all the time. She can no longer hold her bladder at all.
I am à student nurse in France .... and I couldnt thankyou enough for your amazing tutos .. they are so easy to understand and retain !
You guys study medicine/ nursing in English ?
Hey zack, love your videos really helped me and my fiancé Dr.Mudaser Amir. Sadly my baby passed way 2 months ago in June due to B-ALL, he really admired you and watched your lectures day and night, he was a really good and kind doctor. I just wanna say thank you on behalf of him. He really enjoyed watching your videos, he often says this zack guy really enjoy learning and teaching others. Kindly pray for him and remember him.
I respect you for giving your precious time to the viewers, your colleague with regards from Ukraine
Your courses are excellent, and they have helped me significantly in my advanced pathophysiology course. Thank you so much!!
i cant thank you guys enough for this channel. This channel is everything for my studies. You helped me understand the most complicated topics that i cant seem to understand before. Big kudos to ninjanerd team! God bless
I have also watched the videos for Hodgkin’s lymphoma and non-Hodgkins lymphoma today and I just can’t express how much I appreciate you walking through the lymphoblast lines every single time. 😍
I am so glad I found these videos. You are a very talented educator!
Yeeeeeeess!!!! You make things make sense 😭 I had the hardest time in heme class. This is great to review for my final semester!
Thank you for sharing this info. My husband died of acute leukemia but I never got an explanation from a doctor. The illness was very fast (12 weeks, 5 days). Your videos (certain ones) are helping me make sense of the medical records I requested. I realize your audience is likely mostly medical students, but there may be people like me just trying to understand medical matters because sometimes patients and caregivers work with doctors who are too busy. I only learned what his dx was after his death from the dc. So thanks again for your videos and clear explanation.
It’s well
God bless you
❤
Acute Lymphoblastic Leukemia (ALL) is a cancer of the blood and bone marrow that affects the white blood cells. White blood cells fight infection and help protect the body against disease. Bone marrow is the spongy tissue inside bones where blood cells are made. Acute Lymphoblastic Leukemia (ALL) is the most common type of childhood cancer, however it also occurs in adults. It is more common for children to have ALL than adults, however the survival chance is less in adults then in children. The word “Acute” means that the disease usually gets worse quickly if not treated.
Acute Lymphoblastic Leukemia (ALL) affects a type of white blood cell called Lymphocytes, which come in 2 main types: B Lymphocytes and T Lymphocytes. ALL may arise from either type of Lymphocyte. Cases of ALL are either known as B Cell or T Cell ALL. B Cell ALL is the most common.
Acute Lymphoblastic Leukemia (ALL) causes people to produce too many immature white blood cells. Eventually, these cells crowd out normal white blood cells. Without enough proper white blood cells, the body has a harder time fighting infections.
Acute Lymphoblastic Leukemia (ALL) most often occurs in children aged 3-5 and affects slightly more boys than girls. ALL is most common in Hispanic children, followed by those of white and African-American descent. About 3000 people are found to have ALL each year in the United States. Siblings of children with Leukemia have a slightly higher risk of developing ALL, but the rate is still quite low: no more than 1 in 500.
Symptoms of Acute Lymphoblastic Leukemia (ALL) Include:
-Frequent Infections
-Fever
-Easy bruising
-Bleeding that is hard to stop (Nosebleeds or heavy menstrual periods)
-Flat, dark-red skin spots (Petechiae) due to bleeding under the skin
-Pain in the bones or joints
-Lumps in the neck, underarm, stomach, or groin (These are swollen Lymph Nodes)
-Pain or fullness below the ribs
-Weakness, fatigue
-Paleness
-Loss of appetite
-Shortness of Breath
-Dizziness
-Night Sweats
-Unexplained weight loss
-Anemia
Causes of Acute Lymphoblastic Leukemia (ALL):
In most cases, the cause of ALL is unknown. Certain inherited syndromes are linked to an increase of ALL, including Down’s Syndrome, Neurofibromatosis Type 1, Bloom Syndrome, Ataxia-telangiectasia, Li-Fraumeni Syndrome, certain forms of Fanconi anemia, Constitutional mismatch repair deficiency, Diamond-blackfan anemia, Familial PAX5 Syndrome, Familial ETV6 Syndrome, and Familial SH2B3 Syndrome. Acute Lymphoblastic Leukemia (ALL) occurs when a bone marrow cell develops changes (mutations) in its genetic material or DNA. Normally, the DNA tells the cell to grow at a set rate and to die at a set time. In Acute Lymphoblastic Leukemia, the mutations tell the bone marrow cell to continue growing and dividing. When this happens, blood cell production becomes out of control. The bone marrow produces immature cells that develop into Leukemic white blood cells called Lymphoblasts. These abnormal cells are unable to function properly, and they can build up and crown out healthy cells. It’s not clear what causes the DNA mutations that can lead to Acute Lymphoblastic Leukemia (ALL). Young children with ALL may have had genetic changes that happened before they were born. ALL in adults is linked to some carcinogens, including tobacco. Environmental risk factors include significant radiation exposure or prior Chemotherapy. Some hypothesize that an abnormal immune response to a common infection may be a trigger.
So sorry for your loss.
Thanks so much professor,you interestingly make things so cheap
Still need some deep explanation for some sub type. Of each leukemia.great job.thank you sir
Fantastic! Feels great watching a ninja nerd video after ages.
Explanations was really great. But i think you missed other advanced treatment for ALL like T.cell theraphy. It would be great if you could mention the success rates of these treatment types.
Fantastic. My son was just diagnosed with ALL. This was very help to help me understand and communicate with his doctor.
My 17 was diagnosed last week. How’s your son doing??
can always depend on u in making me understand something complex
The long waited lectures. 🎉🎉🎉
Ty ma Zack 💓 ❤🎉 The best prof 🎉🎉
Thank you making this video. I have bettered my understanding so much through using your videos.
Sir , please do videos of remaining hematological diseases like myeloproliferative disorders,myelodysplastic syndrome
Please more hematology lectures please Dr zack
the best doctor in the whole world
Enjoy your teaching style, all things to the point , Great content . Thank you .
NINJA NERDS🤟
Please continue hematology videos.
Thank you very much! Very informative and nicely explained.
Wow, quite impressive! Thank you!
Thank you for the lecture🎉🎉 In the lecture you made reference to AML lecture,but I didn't find any
Thanks so much.....just when I needed it ❤
You saved my hematology exam my dude
That’s what i was looking for, brilliant work !
this man is too powerful
best lectures in my life.
I just got diagnosed with LVH, and I'd like to learn a bit more about it if you have a video on it, or I'd appreciate a video on it. 😊 Thank you for your videos so far.
Finally some hematology😍😍
Thank you! I think that you are one of the professors that made me like medicine by understanding it
Thanks to your videos my teachers love me 😂❤ Thank you!!!
Amazing content and thank you so much for putting in the hours and effort.Stay blessed.
I love the channel, your drawings help me understand the topic in a second!
Excellent lecture.
Please upload more video about leukemia and anemia. This is really helpful.
Thanks a lot.
I freaking love you and your videos. You make it so much easier to understand. I don´t know why, but thank you so much!
Thankyou for these videos ✨
Thank you my guy for all the videos
Amazing explanation as usual, thank you
Great revision and summary as always. Thanks.
You literally have info about everything
Thank you ninja nerd. Your lectures are very helpful
Thank u so much sir...I was able to give presentation very nicely becoz of u😊
You such an incredible teacher I feel like you could run a medical school by yourself
Great presentation
Very good
thank u so much for all of your great helpful content ❤
Damn it took me a week just to grasp tge basic concepts of All and you eluded it all in merely 40 mins. You are a sagaicious Saintvof sorts, please keep uploading these videos ❤❤.
Thank you so much for your efforts, really appreciate it
Thanks doc
I've been waiting for this topic please help me for explaining other types of leukemia becuase i have exam in th next week thanks alot ninja nerd we love you keep going ,thanks again😍🥰🥰
Thank you for clear concept
Thanks
My head is still spinning because very recently I lost my best friend of the past 50 years plus to Leukaemia. He has always seemed well with no health problems at all. In fact we came back from holiday 4 weeks ago and 2 days later he started getting short of breath. He went into hospital and went down very fast. He died 11 days ago after spending less than 3 weeks in hospital. He was 67 but he's always seemed so fit and healthy.Just how can this happen? Please can anyone tell me, thank you.
Thank you
Thanks for devotion of time and knowledge to disseminate content
how are you remember all of these info! Anyway awesome lecture!
mindblowing ....simple as you like 👍
Easy to learn
You are a legend bro! Thank you for your content
I got low lymphocytes 0.72 and found 0.03 blasts in my blood.
Now checking t and B cells.
The rest of the values looked good.
Hoping for the best but am really worried.
More topics of heamatology pls Dr make for us thanks for your efforts
Many thanks Zach
Could you PLEASE do one for multiple myeloma?
Thank you!
Can u please make a video for the Ewing sarcoma?? 👉🏻👈🏻 Ur work is amazing and very helpful ❤
Thank you❤
Thanks for the information!!!
thank you!
MUCH LOVE MAN
Plz make videos on muskuskeletal or orthopedics pathology
SO WHAT DOES THE PCR DO IN ALL?
Arrived at 49 seconds, 17 views already.
Amazing!!!
You have a great way of explaining. I became curious about your undergraduate degree.
Very interesting! I'm going to be starting my masters project in September on developing asparaginase based therapies for ALL
They use asparaginase on my sons ALL b cell
You are soooo amazing I love your videos they are really helpful thank you ❤ ❤ ❤
Amazing ❤
Thanks!
I'm Printing your logo on my shirt and wearing it upon graduation 💀🔥
Where can i find AML video pls
Make a lecture on acute myeloid leukemia
Please! Chronic lymphocytic leukemia and Menigitis note we need.
Ninja nerd>>>
My uncle was diagnosed with ALL which led him to get sepsis and passed away from it. It’s been two years now…
amazing, cant find the pharmacology about the chemotherapies tho!! Thank you
Wonderful! And if all of this fails, we use CAR T cell therapy for the B-ALL
Great dr. Ninja
Thanku sir
thank u so much
Thanks.
Amazing
LOVE THIS!!! YOU THE BEST!