Great presentation. I was diagnosed with MZS Lymphoma, Stage IV (low grade) in 2005, only 5 years after retiring from the Army as a Aviator. I was 43. The one thing I think is very important for diagnosis is how my symptoms presented themselves. Dry cotton mouth, severe itching (mainly where my clothes touched my skin tightly), night sweats, periodic fevers with no infection, and very severe fatigue. I never contributed any one of them to be part of the collective issue. I like to think I’m educated and informed, but there was no way I could have connected them all to NHL. Even the doctors were baffled. I was admitted to the hospital, and for a week I was the Guinea pig for about a dozen residents. There’s nothing more concerning when it comes to my health then watching doctors scratch their heads and not have answers. It took a bone biopsy to find the truth. After my enlarged spleen was removed, I went through CHOP-R (I wouldn’t wish it on anyone), and maintenance treatment for 4 years. I’m still in the fight, and the key for patients is to stay aggressive and informed in your treatment. Including the PET scans and labs as often as possible. What you presented here really helped me understand the process of how it progressed. Thanks
Thanks for sharing your story. The cotton mouth is perhaps the first I've seen where listed on any stories of lymphoma symptoms but makes so much sense. I have a enlarged lymph node but haven't taken the order in to have the ultrasound yet. Waiting g for insurance to kick in. In the mean time I've been going batty with the dry mouth for about 3 weeks, lozenges don't even help and have been wondering whats going on.ive got the severe fatigue too so hanging onto my job by a thread. I hope I don't have lymphoma but answers would help ease my worries. The treatment for yours sounded harsh. Hope you're doing well now. 😊
Hi me too I'm a 63 yr gramma had the fatigue lost 50 lbs stressed the sweats had left marriage moved in w son & they had 2 babies bk to bk I was helping I became a live in baby sitter stressed fatigued 1st stages of non hodgkin's had no clue lived like tht 5 yrs came bk into marriage w regret forced to for severe financial / stressed related I was finally diagnosed in May this past spring of 2024 HOP been stage 3 diagnosed now I was told last week I'm complete Remission have only 2 chemo sessions left
One of the best lecture ever attended on Non Hodgkin Lymphoma ever attended or learnt in my life...too too good...no words to describe the marvellous way in which the concepts are given by the presenter...hats off to you sir
I live vicariously through you. Before I was struck by lightning, I tutored physics, chemistry and calculus. I discovered you exploring Hodgkins lymphoma as I have many symptoms and am trying to get referred to an oncologist. Your videos are amazing! I miss teaching so very much.
I have non-hodgkin mantle cell lymphoma. Going through RBAC chemo after 7 cycle of Retoximab and acalabrutinib. Not sure why RCHOP shows everywhere to tackle the cancer. Presentation was mind blowing, the best so far in YT. Thank you!!
Once again a huge THANK YOU Ninja Team💕 for all your hard work. Team work makes the dream work. All my love to you all. Happy midsummer from Finland 🇫🇮👋!
I had NO symptoms other than a almond sized lump in my neck. Thought it was an infection. 1 month turned into several lumps that started pressing on my windpipe. I was lucky I had a DR that LISTENED to me and took me seriously.
i was watch this awesome lecture from ninjanerd web page, had to come to youtube just to give BIG THUMBS UP.. what awesome way of teaching.. one little suggestion if ninja nerd team could rearrange the web page lecture's in order. thank you again
@NinjaNerdOfficial please explain what you mean here 1:10:23 when you are discussing staging in relation to nodes being on the “same side of the diaphragm “ or “different sides of the diaphragm.” The diaphragm is drawn on your figures it splits the thoracic region from the abdominal region. But when you are explaining it in real time you draw a dotted line down the middle of the figure like a Sagittal section. For ex. Stage 3 is 2+ nodes on “different sides of the diaphragm,” but are you really trying to say it’s 2+ nodes on different sides of the mediastinum?
Excellent presentation. The only thing that I am not ok with is the classification of Ann Arbor: sides of the diaphragm means sub and supra diaphragm and not left to right of the body. Please correct that
Had severe EB mono in my 20’s. At 62 had DLBC lymphoma from taking Humira for 10yr. Crohns Disease. Remission 5 years. RCHOP and Methotrexate intrathecal
As always, you are the best! I appreciate your work and dedication. I'm a MD and I really enjoy and learn a lot from your video. I'd love to know you in person, that would be a huge PLUS! :D
Great presentation. However for the staging ann arbor, different sources show lymphnode involvement for stage 2 on same side of diaphragm i.e above diaghram in chest upwards. If crosses below diaphragm, then stage 3. Not using sagittal plane as diaphragm reference. Kindly throw more light
Zach , i really like your videos and you always make a very thorough analyse of the topic. Just a small correction about ann arbor stages II and III in hl and nhl . Stage 2 means 2 or more groups of lymph nodes affected either above or below the diaphragm and stage 3 means lymph nodes above and below (its not about left or right part of diaphragm)
Hey Zac. Thank you for the video, such a comprehensive and detailed explanation. But in 1:00:47 you mention that the translocation for Follicular Lymphoma is t(11;14), isn't that for marginal cell lymphoma (also Multiple Myeloma)?? You probably meant t(14;18) for Follicular? Please confirm. Thank you again!!
Great videos! Absolute the best. Could you please add normal histology prep of the different NHL next to histopathology. It is difficult for me to know what to look at If I don’t have anything to relate to... Thank you for your interesting videos!
Had a swelling on the right side of neck appear almost overnight, and go away after two weeks or so. Also was noticing weight loss without trying. Months later, found a cancerous tonsil on the right side. Was found to be B-cell non Hodgkins. Determined I was at stage IIIA. Could chronic lung infection from maybe histoplasmosis have led to this? Had the upper right lobe removed. Now in the process of treatment.
Point out one mistake in 59minutes ,Histopathology of genetics u said Follicular Lymphoma from 11:14 translocation but its incorrect nasically its from 14:18 translocation
Great presentation. I was diagnosed with MZS Lymphoma, Stage IV (low grade) in 2005, only 5 years after retiring from the Army as a Aviator. I was 43. The one thing I think is very important for diagnosis is how my symptoms presented themselves. Dry cotton mouth, severe itching (mainly where my clothes touched my skin tightly), night sweats, periodic fevers with no infection, and very severe fatigue. I never contributed any one of them to be part of the collective issue. I like to think I’m educated and informed, but there was no way I could have connected them all to NHL. Even the doctors were baffled. I was admitted to the hospital, and for a week I was the Guinea pig for about a dozen residents. There’s nothing more concerning when it comes to my health then watching doctors scratch their heads and not have answers. It took a bone biopsy to find the truth. After my enlarged spleen was removed, I went through CHOP-R (I wouldn’t wish it on anyone), and maintenance treatment for 4 years. I’m still in the fight, and the key for patients is to stay aggressive and informed in your treatment. Including the PET scans and labs as often as possible. What you presented here really helped me understand the process of how it progressed. Thanks
Thanks for sharing your story. The cotton mouth is perhaps the first I've seen where listed on any stories of lymphoma symptoms but makes so much sense. I have a enlarged lymph node but haven't taken the order in to have the ultrasound yet. Waiting g for insurance to kick in. In the mean time I've been going batty with the dry mouth for about 3 weeks, lozenges don't even help and have been wondering whats going on.ive got the severe fatigue too so hanging onto my job by a thread. I hope I don't have lymphoma but answers would help ease my worries. The treatment for yours sounded harsh. Hope you're doing well now. 😊
Are you still fighting or you win I hope you are doing okey
Hi me too I'm a 63 yr gramma had the fatigue lost 50 lbs stressed the sweats had left marriage moved in w son & they had 2 babies bk to bk I was helping I became a live in baby sitter stressed fatigued 1st stages of non hodgkin's had no clue lived like tht 5 yrs came bk into marriage w regret forced to for severe financial / stressed related I was finally diagnosed in May this past spring of 2024 HOP been stage 3 diagnosed now I was told last week I'm complete Remission have only 2 chemo sessions left
CHOP THERAPY
@@janiceaguilar3593awesome!
Excellent. As an oncologist I can say that this lecture is so true and important for common understanding
Simply the best Professor of Medicine on World Wide Web.
One of the best lecture ever attended on Non Hodgkin Lymphoma ever attended or learnt in my life...too too good...no words to describe the marvellous way in which the concepts are given by the presenter...hats off to you sir
Best medical and physiology videos anywhere on the internet! Thank you for your dedication!
I live vicariously through you. Before I was struck by lightning, I tutored physics, chemistry and calculus. I discovered you exploring Hodgkins lymphoma as I have many symptoms and am trying to get referred to an oncologist.
Your videos are amazing! I miss teaching so very much.
Seriously the best comprehensive, detailed and yet effective explanation I’ve seen on the internet
I have non-hodgkin mantle cell lymphoma. Going through RBAC chemo after 7 cycle of Retoximab and acalabrutinib. Not sure why RCHOP shows everywhere to tackle the cancer. Presentation was mind blowing, the best so far in YT. Thank you!!
Thank you .. This video is on time for my last semester in medical school ...having Hematology in a month! ... This surely made everything way easier
Your dedication to sharing knowledge across the world is unbelievable, Thanks so much
I’m so glad you are making haematology videos because I have an exam in a week and these are the only thing that makes sense to me. Thank you !!!!
Once again a huge THANK YOU Ninja Team💕 for all your hard work. Team work makes the dream work. All my love to you all. Happy midsummer from Finland 🇫🇮👋!
This should be paid. THANK YOU SO MUCH
Absolutely the best explanation I have ever received on this topic,even paid platforms fail to give such detailed and understandable explanation ❤
I was diagnosed with hodgkins lymphoma a year ago my chemo is complete and excited to study the hodgkin and non hodgkin as a med student
Genius . saved my time instead of cluelessly staring at the text books
I am 1yr in remission from diffuse large B cell lymphoma. Thank you for helping me understand my disease.
@1Alchemist420I was stage 2E. Did 3 cycles of R-CHOP chemotherapy followed by 21 treatments of radiation.
I had NO symptoms other than a almond sized lump in my neck. Thought it was an infection. 1 month turned into several lumps that started pressing on my windpipe. I was lucky I had a DR that LISTENED to me and took me seriously.
Thanks a lot! Excellent presentation! Zack, you have a natural uncanny set of skills to teach!!!
Greetings from Colombia. Your presentation skills are A+.
Thank you very much, great explanation from start to finish.
You first talk about physiopathology and until you finish to treatment. We are grateful.
Okay but ninja nerd uli chi pondo..👌 From a mad scientist to a Ninja nerd. I salute
Zambia ku caalo😂... I just had to like your comment
Thank God for Dr. Zach!! 🙏🏼❤
Im literally only passing my exam because of your videos. Forever grateful ❤
Thanks for this content I don't realize this much in class❤
I have been waiting for this lecture. Thank you sir!
Excellent excellent excellent....world great top teacher you are sir...keep it up..God bless you
i was watch this awesome lecture from ninjanerd web page, had to come to youtube just to give BIG THUMBS UP.. what awesome way of teaching.. one little suggestion if ninja nerd team could rearrange the web page lecture's in order. thank you again
@NinjaNerdOfficial please explain what you mean here 1:10:23 when you are discussing staging in relation to nodes being on the “same side of the diaphragm “ or “different sides of the diaphragm.” The diaphragm is drawn on your figures it splits the thoracic region from the abdominal region. But when you are explaining it in real time you draw a dotted line down the middle of the figure like a Sagittal section. For ex. Stage 3 is 2+ nodes on “different sides of the diaphragm,” but are you really trying to say it’s 2+ nodes on different sides of the mediastinum?
It should be above/bellow
Excellent presentation. The only thing that I am not ok with is the classification of Ann Arbor: sides of the diaphragm means sub and supra diaphragm and not left to right of the body. Please correct that
THANK YOU and THE TEAM behind this channel ❤❤
Had severe EB mono in my 20’s. At 62 had DLBC lymphoma from taking Humira for 10yr. Crohns Disease. Remission 5 years. RCHOP and Methotrexate intrathecal
Biologics can kill. I was on Remicade for nine years, it gave me NHL. It wasn’t worth it.
Love your presentations. They are very informative and helpful. Thank you
I am overflowing with knowledge 🧐
Love this stuff, please do some more!!
Tnx professor Zach you are the best teacher I've ever seen❤❤❤❤❤❤❤❤❤
Excellent presentation
Wow, you're an amazing teacher.. Thank you so much for doing this... Now, I can talk to my doctor and know more what he's talking about. 🙏
Just amazing, well planned lecture. Thank you. Also a new subscriber here.
Thanks a lot Professor Zac from 🇿🇲🇿🇲🙏
A BIG THANK YOU FROM UGANDA.
I have been looking for this after watching Hodgkin lymphoma
Where’s the Hodgkin videos pls
Thank you may God bless your work you make my studies easy
Huge respect for u guys❤
Uploaded right after my hematology exam😭 passed though thanks to the other hematology videos🙏
1:00:46 Correction = " Follicular cell lymphoma " is associated with chromosomal segment translocation between chromosomes 18 & 14 ; t(14,18) NOT chromosomes 11 & 14 ; t(11,14) .
Correction: It is t(14;18) not t(18;14)
Colon cancer
Breast cancer
Ebola virus
Sir these all topics are very important, please make a video on these topics
Thank you sir
Thank you so much for your lectures on Hodgkin’s and non-Hodgkin’s lymphoma! Learned so much. Can you talk about HLH next?
You really are a great teacher! ❤️
As always, you are the best! I appreciate your work and dedication. I'm a MD and I really enjoy and learn a lot from your video. I'd love to know you in person, that would be a huge PLUS! :D
best medical videos at all
You’re a genius teacher
Brilliantly explained & presented! Thank you!
Amazing presentation❤
Perfect presentation…very inspiring….Great instructor
Can’t thank you enough Dr.Zach😊
Awesome presentation- thank you
Amazing lecture! Thank you very much for your dedication
Rockstar! Very informative and I didn’t die of boredom!
And we had this same lecture in class a day ago. Coincidence!!
thank you Zac,very informative
Great presentation. However for the staging ann arbor, different sources show lymphnode involvement for stage 2 on same side of diaphragm i.e above diaghram in chest upwards.
If crosses below diaphragm, then stage 3. Not using sagittal plane as diaphragm reference. Kindly throw more light
You are really awesome , great lecture ..Multipl Myeloma please 🙏only you can do it properly and perfectly
Great video. Just a little addition; P53 will suppress proliferation so the mutation in cancers inhibits p53 (like in diffuse B-cell lymphoma)
Your lectures are too good
Thank you for explaining!!! I'm doing Gazyva infusions and Venclexta tablets Monoclonal Antibodies are a real game changer!!!!!
Absolutely amazing 🤩😍😍
I love your video so much, thank you for giving us such useful information
Superb lecture 😊
Amazing!!!!!!!!! Loveee it!!!! Thankyou so much, you're extremely good mentor
Zach , i really like your videos and you always make a very thorough analyse of the topic. Just a small correction about ann arbor stages II and III in hl and nhl . Stage 2 means 2 or more groups of lymph nodes affected either above or below the diaphragm and stage 3 means lymph nodes above and below (its not about left or right part of diaphragm)
Excelent video you really helped to me as a med student
At 1:00:55 you made a mistake the follicular cell lymphoma is a mutation in 14;18
Thank you for your dedication!
Thanks Mr Zac ❤❤
You are awesome!!! Thank you so much! 😊❤
Because of ninja nerd I learnt ecg from you only
Hey Zac. Thank you for the video, such a comprehensive and detailed explanation.
But in 1:00:47 you mention that the translocation for Follicular Lymphoma is t(11;14), isn't that for marginal cell lymphoma (also Multiple Myeloma)?? You probably meant t(14;18) for Follicular?
Please confirm. Thank you again!!
Thank you for the hard work
Perfect as always ❤
Great as always
Thank you
سپاس فراوان
Wow. Thank you so much, so much to learn.
Thanks for all you DO🙌🙌. Zach! A video on Renal tumours won’t be a bad idea🙂
Amazing lecture.
amazing as always
Thank you sir 😊😊
Great video, as always. Thanks!
Great work,,,, Very easy to retain now,,,
Thanks from India 👍
Great videos! Absolute the best. Could you please add normal histology prep of the different NHL next to histopathology. It is difficult for me to know what to look at If I don’t have anything to relate to... Thank you for your interesting videos!
May Allah protect you .
Thank you so much!!!
Had a swelling on the right side of neck appear almost overnight, and go away after two weeks or so. Also was noticing weight loss without trying. Months later, found a cancerous tonsil on the right side. Was found to be B-cell non Hodgkins. Determined I was at stage IIIA. Could chronic lung infection from maybe histoplasmosis have led to this? Had the upper right lobe removed. Now in the process of treatment.
How's treatment going?
@@catherineero1317 Just a year out from last chemo, and still in remission as far as I can tell.
I love your videos, you help me so much!
Point out one mistake in 59minutes ,Histopathology of genetics u said Follicular Lymphoma from 11:14 translocation but its incorrect nasically its from 14:18 translocation
litrly just came here after hodgkin lymphoma and was like where is non hodgkin lymphoma . i feel like u read my mind sir 😆😁
u r great abd dedicated teacher. thank you
thanks for this class❤❤❤❤❤
Please upload two lectures in a week.
Too bad I cant just pay you instead of my university....
Thank you Dr Zach
great lecture ..thank you