Why Naltrexone Doesn't Work for Everyone - The Sinclair Method for Alcoholism

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  • Опубліковано 27 лис 2018
  • Dr. John Mendelson discusses why naltrexone, although effective for many people, doesn't always work for everybody as a medication to stop drinking.
    Learn more at riahealth.com/youtube/
    Subscribe: / @riahealth
    In this video, Dr. Mendelson, addiction specialist speaks about the medication naltrexone when used for alcohol use disorder. While the medication is proven to be very effective for many people, it unfortunately does not work for all. Dr Mendelson speaks to the scientific reasons as to why naltrexone doesn't work for everyone.
    Ria Health delivers evidence-based care that includes medications, one on one support, a digital app, and progress tools. We support people who want to either reduce or stop drinking with the care of an expert medical team and community support.
    We use safe and FDA approved medications such as naltrexone, which is the cornerstone of the Sinclair Method. We also support not for profit advocates that promote awareness of options for people who want to change their relationship with alcohol. We are proud sponsors of Claudia Christian's CThree Foundation and Moderation Management.
    Learn more about the Sinclair Method: riahealth.com/sinclair-method/
    Ready to get started? Visit riahealth.com/begin-now/
    Contact us at:
    www.RiaHealth.com
    800-504-5360
    Hello@RiaHealth.com
  • Наука та технологія

КОМЕНТАРІ • 137

  • @RiaHealth
    @RiaHealth  4 роки тому +1

    Find out how Ria Health's program can help you drink less from home at riahealth.com/how-it-works/ or schedule a call with a team member at member.riahealth.com/member/register/start/info

  • @kevindaniel2328
    @kevindaniel2328 4 роки тому +40

    I have 0 side effects , and this pill is changing my life for the better. 🙏 for everyone

    • @arlenepearson1924
      @arlenepearson1924 4 роки тому +3

      I had zero side effects as well. I did TSM for 14. Today I'm alcohol free.

    • @hankmoody5514
      @hankmoody5514 4 роки тому +2

      Can you please tell me how you take it? I've been doing an hour before drinking for about a week? Does it take longer to work?

    • @arlenepearson1924
      @arlenepearson1924 4 роки тому +4

      @@hankmoody5514 Yes, one hour before drinking is the protocol. It took me 14 months to reach extinction, but everyone is different. Some people respond much faster. The book by Roy Eskapa, ",The Cure for Alcoholism ", explains the Sinclair Method and should answer any questions you may have.

    • @hankmoody5514
      @hankmoody5514 4 роки тому +2

      @@arlenepearson1924 cool. I was thinking it'd be overnight. It going to take some time then. Thanks

    • @arlenepearson1924
      @arlenepearson1924 4 роки тому +2

      @@hankmoody5514 Dont get discouraged during the process. There were times when I was still drinking a lot, probably about 7 to 9 months into the process. There are wonderful Facebook groups to support you through this. I drank for decades and tried EVERYTHING to stop. Nothing worked for me like Naltrexone. The page I started with was Sinclair Method Warriors. They have additional pages as you progess. I wish you all the best.

  • @Foxyfreedom
    @Foxyfreedom Рік тому +4

    After day two of naltrexone I threw up my $20 breakfast. So not only do I still have an alcohol problem, now I have stomach problems. See this is the problem with modern “scientifically supported” treatments. Sure psilocybin treatment is anecdotal but I don’t end up with more problems afterwards.

  • @stubdo16
    @stubdo16 4 роки тому +3

    Really interesting interview and content 👍

  • @FahadShah822
    @FahadShah822 3 роки тому +2

    Dr. John Mendelson is a wealth of knowledge.

  • @rhondabeckman9380
    @rhondabeckman9380 5 років тому +1

    Good info !

  • @stevecooper7038
    @stevecooper7038 4 роки тому +18

    But it DOES work for 8 out of 10 people who are complient with The Sinclair Method of using Naltrexone.

  • @reallycoolguy121
    @reallycoolguy121 5 років тому +4

    Awesome information. Thanks for all you do.

    • @RiaHealth
      @RiaHealth  5 років тому

      Thanks for the comment! We appreciate it.

  • @johna3357
    @johna3357 2 роки тому +6

    I don't have any side effects but it seems to have no or very little effect on my drinking. I just drink right through it

    • @RiaHealth
      @RiaHealth  Рік тому

      Naltrexone works for most people, but not for all. You might want to discuss with your doctor, and they can give you the best advice on whether this is the best method for you.

  • @user-yx1uf5gf7b
    @user-yx1uf5gf7b Рік тому +3

    Hasnt done anything for me, drinking the exact same amount. Damn. I thought this was my answer....guess not :(

    • @kkw-pal1178
      @kkw-pal1178 Рік тому

      Me too. 🙄

    • @user-yx1uf5gf7b
      @user-yx1uf5gf7b Рік тому

      @@kkw-pal1178 S0rry to hear. There is no quick fix miracle pill for this alcoholic

    • @CrazyCoon100
      @CrazyCoon100 5 місяців тому

      Try BACLOFEN

    • @marysiddiqi3630
      @marysiddiqi3630 3 місяці тому

      It takes a while for some to get in your system. I know some people months and one lady said finally after a year she’s not been drinking. It took that long.

  • @bluesdirt6555
    @bluesdirt6555 Рік тому +1

    I feel high ,foggy headed,forgetful, but it seems to be working. Maybe part withdrawals I’ve been drinking for years. .

  • @kkw-pal1178
    @kkw-pal1178 Рік тому +2

    Maybe I'm one that it doesn't work for. 5th week and it's like, ummmm🤔

  • @elizagreenesmith
    @elizagreenesmith Рік тому +1

    Okay so I’m a month in and the side effects are a little less - at first it was like I was sooo high, and sleepy, it was like being drunk with out the payoff. And that was BEFORE I would have a drink. And then drinking would be less appealing because everything was less appealing. Now I still feel discombobulated but less so. I’m worried I’m the 10%

  • @normanlanier6196
    @normanlanier6196 Рік тому +2

    As an opiate will Naltrexone show up one a work place or probationary drug screen?

  • @chrislewis73
    @chrislewis73 2 роки тому +2

    I have side effects the naltrexone hangover/ terrible dreams super vivid. I gonna gut thru this . its my life. I have to beat this! I am now trying to master lucid dreaming, If I am gonna have to endure this I guess I gotta make the best of it!

    • @mojoriiisn
      @mojoriiisn 2 роки тому +1

      Lucid dreaming is the best!

  • @surfhealthy4272
    @surfhealthy4272 Рік тому +4

    taking naltrexone.....doesn't work for me...interest in drinking is still there.

    • @RiaHealth
      @RiaHealth  Рік тому +1

      Good for you for giving it a try, but it doesn't work for everyone. That said, it is not an instant fix. It takes time to change patterns, and we also recommend combining it with counseling, for the best results.
      Wishing you success in drinking less, whichever method works best for you.

  • @Sharon-tb9yh
    @Sharon-tb9yh 5 років тому +4

    Thank you for this info, now I know why I had nausea.

  • @rosarutherford9352
    @rosarutherford9352 Рік тому

    December 19
    If naltrexone is not successful what are the alternatives that can be discussed with my health provider?

  • @MattMendians
    @MattMendians Рік тому +1

    I started it a few days ago and it seems to make me extremely sleepy!

  • @jackster1212
    @jackster1212 3 роки тому +7

    The family member we've tried to help by encouraging him to get on naltrexone was getting good results with the regular use pill, but fell off the wagon and felt he should start getting the monthly shot instead. Unfortunately, he started just drinking through the shot. And he's now an even heavier drinker. Not sure what to do next...

    • @RiaHealth
      @RiaHealth  Рік тому +1

      Apologies for the late reply, and hope your family member is doing better. Naltrexone alone won't necessarily solve the problem, it works best combined with counseling.
      Definitely discuss with your doctor, and we wish your family all success.

    • @CrazyCoon100
      @CrazyCoon100 5 місяців тому

      If your family member has a history of trauma, have them try BACLOFEN
      A reason that people MAY “drink through” the pleasure receptor blocking effects of naltrexone is very often because they can still use alcohol to escape trauma.
      Does your loved one have a history of trauma? Did their drinking start getting heavy after that trauma?

  • @danielafantauzzo8551
    @danielafantauzzo8551 Рік тому +1

    I don't see that he is answering the real question of why it may not work for eveyrone. Only that some people can't tolerate side effects. I'll continue watching to see if this changes.

    • @AM-xh8zn
      @AM-xh8zn Рік тому

      I agree, I can't figure out if he is saying those who experience naltrexone as a cappa antagonist are immune or just uncomfortable...

  • @readytogo5115
    @readytogo5115 4 роки тому +1

    For some the supplement l glutamate, might help.

  • @juliebraden4865
    @juliebraden4865 4 роки тому +10

    I guess I need to preface by saying I have backslid into drinking. I go 3 to ten days sober. Then binge. Why can't they understand???

  • @richardharris9708
    @richardharris9708 Рік тому +3

    It worked instantaneously for me and I stopped wanting to drink... but a few months later I had a strong cider while on naltrexone and got the usual dose of opiates. No side effects but it seems to work inconsistently for me (on 50mg/day)

    • @OnTheFritz602
      @OnTheFritz602 Рік тому

      Using the method properly, you take it *only when you know* you're going to drink.
      1 hour before.

    • @richardharris9708
      @richardharris9708 Рік тому

      @@OnTheFritz602 I've done that but it still doesn't work reliably for me :(

  • @Scratch1980
    @Scratch1980 3 роки тому +1

    It doesn't work for me very well.

  • @wheatstonebridge
    @wheatstonebridge 3 роки тому +3

    My doctor said it could be that there are many life stresses in their lives and they still do make part of an effort to drink less, along with the pill.

    • @RiaHealth
      @RiaHealth  3 роки тому

      That is a great point.

    • @danielafantauzzo8551
      @danielafantauzzo8551 Рік тому

      Very interesting.

    • @kkw-pal1178
      @kkw-pal1178 Рік тому

      Completely agree.

    • @CrazyCoon100
      @CrazyCoon100 5 місяців тому

      I will write it one more time. A huge reason that people can drink “through“ the naltrexone because they are not drinking because it’s adding pleasure to their life. They are drinking to escape the after effects of trauma. Ask yourself if your loved one has had significant trauma in their life. Also ask if they started drinking after That trauma happened. Or if they have a history of childhood trauma. If the case is that they do, have them try. BACLOFEN

    • @CrazyCoon100
      @CrazyCoon100 5 місяців тому

      Also, these comments are kind of saying that it’s the fault of the person for developing an alcohol or substance abuse disorder, because they reacting to trauma. If you’re loved one has trauma, especially complex trauma, it’s an entire syndrome that affects their entire nervous system.

  • @angeloarteaga1930
    @angeloarteaga1930 3 роки тому +1

    I had taken the shot drank 4 days later felt very weird and not well felt like my head was under alot of pressure.. how long does it stay in the system?

    • @RiaHealth
      @RiaHealth  3 роки тому

      Hello there! Here is an article about Vivitrol: riahealth.com/2019/05/16/vivitrol-naltrexone-alcohol/

  • @welder1357
    @welder1357 4 роки тому

    Funny I thought this was a live feed or just recorded yesterday I'm watching it exactly one year later LOL doing my research today hoping that my insurance and doctors will consider this treatment

  • @corrinamatus3865
    @corrinamatus3865 4 роки тому +3

    Do you know if neltrexon is safe for a person who already has nacortimg pancertitis and high liver levels has tried vegerously to stop drinking and relapse every time suffering from deperssion now of feelings of failure and sadness he is only 26 and wants his life back so bad . Would Neltrexon be safe for him ???

    • @kateri222
      @kateri222 4 роки тому

      I read that you cannot be in the middle of withdrawal, must be 7-10 days after. I also read that you shouldn't take it if you have Liver issues.

    • @kateri222
      @kateri222 4 роки тому

      This video also says that Naltrexone can create liver problems- rarely.

    • @corrinamatus3865
      @corrinamatus3865 4 роки тому +1

      @@kateri222 Thank you kateri solberg I will look into more info about this appreciate your reply.Thanks

    • @madisoncrispo2936
      @madisoncrispo2936 3 роки тому +1

      Hi Corrina, I’m wondering how this person you spoke of is doing?? Sending love and strength ❤️

  • @zsmith5575
    @zsmith5575 4 роки тому +1

    What are the other medications Dr. Mendelson is referring to besides Naltrexone?

    • @RiaHealth
      @RiaHealth  4 роки тому

      Here's a list of some of the most common ones: riahealth.com/medication-for-alcoholism

  • @CrazyCoon100
    @CrazyCoon100 5 місяців тому

    In my experience, with TSM, people who are drinking to add pleasure and relief from stress will find success with no truck zone. But people who are using alcohol because of wanting to escape from the ruminating thoughts and panic and nervous system dysfunction caused by TRAUMA need baclofen. So technically, the alcohol still “works” for people who are using the alcohol to regulate their nervous systems, and to escape the rumination and panic of trauma.
    It’s very frustrating for me to listen to interviews with doctors who are supposed to be specialist in addiction and they don’t bring up the idea of why people are drinking. They just talk about chemistry and how to fix biology. The why a person is drinking is so important.

  • @unstoppablezone4980
    @unstoppablezone4980 3 роки тому +2

    What other medications?

    • @at9048
      @at9048 2 роки тому +1

      Naloxone

  • @napoleonwilson5461
    @napoleonwilson5461 Рік тому +2

    I haven’t had a drink for 3.5 years but I would like to drink again….just not binge and go overboard like I did back in 2019. Could naltrexone keep my drinking safe?

    • @RiaHealth
      @RiaHealth  Рік тому +1

      Of course, everyone is different, and you should definitely talk with your doctor. (And like every method for dealing with alcohol issues, naltrexone doesn't work for everyone.)
      But yes, our studies show that many people can "relearn" how to drink moderately, with a combination of naltrexone and counseling.

    • @napoleonwilson5461
      @napoleonwilson5461 Рік тому

      What if you are also taking Wellbutrin (bupropion)???

    • @napoleonwilson5461
      @napoleonwilson5461 Рік тому

      hi riahealth .... I started naltrexone about 7 months ago and could drink moderately. however recently I missed a few doses and ended up on a two day binge without eating I came out of it Monday and it took 5 days to detox and recover. just wondering if it was simply because I missed a few doses or if my alcoholic tendencies are back? remember I did stop drinking completely for 3.5 years.........any help or advice would be appreciated.

    • @theycallmedip
      @theycallmedip Рік тому

      ​@@napoleonwilson5461 my understanding is that you can't miss a dose otherwise the addiction will come back in full force.

  • @patriciagraham9007
    @patriciagraham9007 Рік тому +1

    I take 150 buporion and 50 of naltrexone

  • @juliebraden4865
    @juliebraden4865 4 роки тому

    Now I'm scared shitless! I have terrible debilitating neck/left body muscle spasms. Ya...can't drive, eat, or be seen in public when they hit! Been 9n numerous muscle relaxers. NONE work! Like taking a placebo. Only thing that keeps them at bay r either Xanax or Ativan. And so many ERs and docs think I'm drug seeking! Just don't want to be debilitated! I can function and work taking Xanax or Ativan (prefer Attivan). And I don't abuse taking too much. I conserve when I can for need when desperste.

  • @aphysique
    @aphysique 4 роки тому

    Doc, would luv to hear your thoughts on Buprenorphine?

    • @RiaHealth
      @RiaHealth  4 роки тому

      Great question! This is definitely something that requires one-on-one medical advice with an experience physician who knows you. Sorry we can't provide more guidance on here. We are always here to help - riahealth.com/how-it-works/ or 800-504-5360. Wishing you the best.

    • @jmr6117
      @jmr6117 4 роки тому +1

      Esoteric Fitness thats the same of methadone..worst drugs you can use ..don't do it..i can tell..

    • @aphysique
      @aphysique 4 роки тому +3

      @@jmr6117 not the same at methadone, not even close bud

    • @murkstalinskitm5334
      @murkstalinskitm5334 4 роки тому +1

      Dr. Philly over here 😂 a quick Google search could have prevented your ignorant comment.

    • @loudsqueak
      @loudsqueak Рік тому

      ​@@aphysiqueyou canadian bud ? Haha

  • @avitolourenco
    @avitolourenco 4 роки тому +1

    What about someone with Liver cirrhosis?

    • @RiaHealth
      @RiaHealth  4 роки тому +1

      Hello! Great question that you could certainly speak with a physician about. Here is some more information about a medication that may be helpful for some in this case: riahealth.com/baclofen/

  • @shantanuroy6432
    @shantanuroy6432 4 роки тому

    my doctor prescribed nodict 50 which is naltrexone...my doctor adviced half tablet every alternative days...which is around 25 mg..but yesterday i have taken it...i got massive heaeche...hallucination.feverish..sleep problems...itchy..and today my head is shaky and bit drowsy...should i also break the 25 mg dose

    • @margaretwhite7067
      @margaretwhite7067 4 роки тому +1

      25mg every other day still seems too high. You should try to cut in half again, if possible.

    • @shantanuroy6432
      @shantanuroy6432 4 роки тому

      @@margaretwhite7067 thanks for the suggestion...but now i am little tensed that my doctor again adviced me to take 25 mg which is half of nodict 50 with 2 tabs of zolfresh 5(zolpidem) before bedtime after 2 to 3 days...i ve no idea what do...its about am i taking a risk again..

    • @jewelzinthelotus
      @jewelzinthelotus 4 роки тому +1

      @@shantanuroy6432 you can dilute the 50 mg into 50 ml of distilled water and then take 1-5 ml/day as low dose naltrexone lots of vids on this

  • @readytogo5115
    @readytogo5115 4 роки тому +1

    The pill form didn't work me,don't that mean the shot want work either.

  • @joshgreer3527
    @joshgreer3527 Рік тому

    I'm starting it soon scared it won't stop me from drinking and I've got a lot of stumic and health problems have colitis after they took my gallbladder out I'm scared to death its going to make my stomach hurt more have to wait a week before I can take it I decided I wanted to drink one more time like a dumb ass guess I needed to get sick one more time and my girlfriend couldn't stay with me I get worried when I take a new pill because I take a lot of medication

  • @unsignedredefined7525
    @unsignedredefined7525 2 роки тому +1

    I'm trying this with bupropion for weight loss. It doesn't seem to be working, I get some nausea and constipation but just a little. No other side effects and I'm taking 25 mg which is a lot more than is typically prescribed. I'm still getting food cravings and overeat, and weirdly alcohol cravings and I don't drink? I am now wondering what is going with my opiod receptors.

    • @RiaHealth
      @RiaHealth  Рік тому

      Definitely discuss these symptoms with your doctor. They can take a look and (hopefully) figure out what the issue is.

  • @michaeloakes2200
    @michaeloakes2200 5 років тому +3

    i took naltrexone last nite threw up dry heaves in morning slept all day

    • @RiaHealth
      @RiaHealth  5 років тому +3

      We're so sorry to hear you got sick! Are you working with a physician for your naltrexone? Nausea is a side effect for some people early on. However, many people can build up a tolerance to it over time and overcome the nausea. Often doctors will have people start at a small dose and allow them to work up to a higher dose. Hope that helps!

    • @gamerdaddy
      @gamerdaddy 5 років тому +2

      Nausea and sleeping all day long (on the day after taking the medicine, I mean) are tottaly normal side effects.

    • @aluna167
      @aluna167 4 роки тому +2

      I started with 1/2 of a 50 mg and was nauseated for 2 days then I took 1/4 for 2 days and slowly went up to 50 mg. Start with small doses.

    • @407Maddi
      @407Maddi 4 роки тому

      @@gamerdaddy Why take this if you get the same hangover like effect lol.

    • @gamerdaddy
      @gamerdaddy 4 роки тому

      @@407Maddi Hahaha... Sad, but I have to say it... I quit Naltrexone... The medicine DID work for me. My problem was the aftermatch. I've gotten depressed, so I decided to come back to drinking. I wish you guys a better luck than mine. :(

  • @candiereasoner5081
    @candiereasoner5081 3 роки тому +1

    I have been on Naltrexone for going on 4 Months and still can drink normal ??

    • @madisoncrispo2936
      @madisoncrispo2936 3 роки тому +1

      Same… me 2 months… have you noticed any changes yet now??

    • @kkw-pal1178
      @kkw-pal1178 Рік тому

      5 weeks and nothing

  • @juliebraden4865
    @juliebraden4865 4 роки тому +5

    That's what I get for being honest with my nurse practitioner. I take (minimal) dosage Xanax .5mg for anxiety. Had appt with her today. I opened up about wanting to try Naltrexone. She not only shut me down, she has taken away my .5mg Xanax, which I truly need for anxiety! What now??? I'm mad at myself for being honest. I've now been left to get my much needed Xanax (.5mg) through the internet!!! I'm poverty level and on Medi-Cal. NOW wtf do I do? 🥺 I feel EXTREMELY betrayed and now left out in the cold. EF this sh**! And then docs wonder why we need to be guarded lest our needed meds r cut off. 🥺🥺🥺🥺🥺🥺🥺🥺🥺🥺🥺🥺

    • @VAMR-vc7xg
      @VAMR-vc7xg 4 роки тому +3

      So sorry this has happened to you.

    • @jmr6117
      @jmr6117 4 роки тому +2

      Julie Braden i hope you learned the lession and don't tell shit to the doctors they just want you to be fuck up all your life...i hope you can get your medication some how..change the dr,and the insurance...

    • @murkstalinskitm5334
      @murkstalinskitm5334 4 роки тому

      The Dr cut you off because you admitted to having an alcohol problem while taking a benzodiazapine. They did you a favor

    • @juliebraden4865
      @juliebraden4865 4 роки тому

      @@murkstalinskitm5334 Yes right. Keep telling yourself that. Maybe u mean well, but u know not what u talk of in this case. Thank u for caring?

    • @juliebraden4865
      @juliebraden4865 4 роки тому

      "The doctor." Pulease.

  • @gabec6522
    @gabec6522 2 місяці тому

    Day 1 on it and horrible response on it.

  • @hankmoody5514
    @hankmoody5514 4 роки тому +1

    I've been taking it for a week orally (an hour before drinking). I still drink like a fish, should I get the shot?

    • @RiaHealth
      @RiaHealth  4 роки тому +2

      Definitely talk with your doctor about what is best!

    • @enlightenedfight9860
      @enlightenedfight9860 3 роки тому

      how about now?

    • @hankmoody5514
      @hankmoody5514 3 роки тому +4

      @@enlightenedfight9860 sober for 6ish months. Stopped taking it a month or so ago. Whenever I get a craving I pop one. I drink NA beer now. So far so good.

    • @hankmoody5514
      @hankmoody5514 3 роки тому +1

      @Nikita it took a couple weeks to kick in. I stopped taking it a month or so ago. 7ish months sober so far

    • @crodgers383
      @crodgers383 3 роки тому

      Mo shit. I don't see an answer for this.

  • @Michael-tr7uq
    @Michael-tr7uq 3 роки тому +1

    Great info. But wish this video was titled "Why Naltrexone only works for about 80% of the population"

    • @RiaHealth
      @RiaHealth  3 роки тому

      Good suggestions! We will re-consider the title...

  • @teeduck
    @teeduck 5 років тому +4

    All drugs are like this 50/50. . chance it helps

  • @alecsimms9653
    @alecsimms9653 5 років тому +3

    Yeah,but does it stop PAWS,you know feeling like hell for months?

  • @lisashoare7381
    @lisashoare7381 5 років тому +2

    :)

  • @user-yn9mp4bt3q
    @user-yn9mp4bt3q 4 роки тому

    Red pill 💊

  • @BetterBlue
    @BetterBlue 4 роки тому +1

    A FORM CAUSED YOU PROBLEMS. WILL A FORM HELP YOU OUT OF THEM? ARE THEY DIFFERENT? iN YOU I YOURSELF. FORMLESS. THOUGH THE MEANS OF HELP ARE DIFF FOR EVERYONE, REMEMBER TO SINCERELY ASK YOUR cREATOR TO HELP YOU YOU FROM IN. rISE ABOVE THE FORMS OF THE WORLD. YA, YOU CAN.

  • @plusbonus1165
    @plusbonus1165 4 роки тому

    No no no .
    Terrible ' medicine' .
    Don't mess yourself up on this dangerous stuff .
    His explanations are good regarding the side effect except the total despair/suicidal thoughts.