Auricular vagal nerve stimulation in patients with mild cognitive impairment

Elinor Ben-Menachem, MD, PhD, University of Gothenburg, Gothenburg, Sweden, discusses vagal nerve stimulation (VNS) to treat Alzheimer's disease. An Alzheimer's study in 2001 showed that VNS improved cognition while decreasing tau in the cerebrospinal fluid (CSF). Recently, a randomized, double-blind study of auricular VNS in patients with mild cognitive impairment showed statistically significant improvement in ADAS-Cog scores in the VNS group, compared to the placebo group. Other notable outcomes included an improvement in verbal memory probing tests, which was lost in the subsequent untreated period. This interview took place at the European Academy of Neurology (EAN) Annual Meeting 2024 in Helsinki, Finland.
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