Gene Therapy Explained

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  • Опубліковано 19 гру 2024

КОМЕНТАРІ • 192

  • @poppyshaikh1300
    @poppyshaikh1300 6 років тому +68

    I am studying 11th-grade biology, from childhood I was interested in genetic engineering, I wanted to become GE, and I am researching gene therapy.... And after watching this video i would like to tell actg channel to upload more videos.. Thanks

    • @BikashDas-hm6zg
      @BikashDas-hm6zg 4 роки тому +2

      I also like biology & want to be a GE . Ty sister

    • @ms-finearts5186
      @ms-finearts5186 3 роки тому +1

      i am in 9th grade and i get this topic in detail haha

    • @josyv4579
      @josyv4579 2 роки тому +1

      Wow this is so good to hear, hope you started majoring in genetic engineering

    • @poppyshaikh1300
      @poppyshaikh1300 2 роки тому +5

      @@josyv4579 thank you so much☺i'm doing microbiology as a major stream and in a 2nd year...hope so I'll do genetics in master's degree

    • @josyv4579
      @josyv4579 2 роки тому +1

      @@poppyshaikh1300 I wish you all the best ❤❤

  • @el_engineer0p106
    @el_engineer0p106 4 роки тому +54

    Writing a paper for BIO. Had to watch like 10 times.

    • @user-vd8nm8sv6x
      @user-vd8nm8sv6x 3 роки тому +3

      THIS UGH :/ is it just me or is this video bad at explaining? the monotone and voice makes it SO hard to pay attention, and the visuals, while interesting, feel…cold and kind of sterile? It feels like a commercial (though, I guess it is lol!)

    • @klam77
      @klam77 3 роки тому

      see you in medical school!

  • @Kurt_707
    @Kurt_707 7 років тому +79

    I have a form of this called Rod Monochromatism so I really hope that one day this could treat my disease. I'm so happy that there are people actually working on a cure for me and others like me

    • @joeyvillanueva4607
      @joeyvillanueva4607 7 років тому +1

      try ageloc

    • @warioland523
      @warioland523 7 років тому

      Gene therapy is becoming a major field of research recently. We discuss these types of things over on this biotechnology server here. Feel free to join in. discord.gg/ftSbffu

    • @pmz558
      @pmz558 6 років тому

      old up there buddy imma help ppl like ya one day

    • @biologyhub94439
      @biologyhub94439 5 років тому

      Say true

    • @brainwashedbyevidence948
      @brainwashedbyevidence948 5 років тому

      Tricky....you'd have to design a vector to discriminate between cone types to deliver the correct genes to the right cell

  • @shelleysmith9709
    @shelleysmith9709 6 років тому +63

    Great video, explains gene therapy so well for us mere mortals.

    • @Luigi_Mario_1997
      @Luigi_Mario_1997 4 роки тому +1

      You say “mere mortal” like you’re some whiny emo.

    • @navinsawesomeanddivineacco4221
      @navinsawesomeanddivineacco4221 4 роки тому

      I'm a mere Mortal :p

    • @usainiyahuza8034
      @usainiyahuza8034 2 роки тому

      #droigiangbe you are the best herbalist online no doubts. After using your herbal medication and getting cured I believed you for life and immediately my trust grew up more for you. I sincerely believe lots of people gonna despise you and blaspheme you for no reasons but they don’t know what they’re missing. You’re a powerful healer of herpes. You be my doctor forevermore for life. I rest my case . contact #droigiangbe on UA-cam'''''

  • @ginosanchez7
    @ginosanchez7 5 років тому +8

    It just so happens I’m writing a research paper on gene therapy for my microbiology class... extremely glad I stumbled across this lol

  • @zahraiqba765
    @zahraiqba765 7 років тому +35

    The music in this video is so pleasant

  • @kr-1543
    @kr-1543 3 роки тому +4

    Cobid 19 Vaxine.
    (Misspelled for obvious reasons)

  • @Zzz21140
    @Zzz21140 Рік тому +2

    Explained really well

  • @marklee3570
    @marklee3570 3 роки тому +1

    $AGTC will be a game changer. Got some shares at $3.95 in Jan before the surge. Lots of 'eyeballs' are on this company now. AGTC FTW!

  • @yeshwanthreddy268
    @yeshwanthreddy268 3 роки тому +1

    UA-cam have dh12 gene mutation so I can participate in clinical trial I am staying in India CEO at present there is any treatment for th 12 gene mutation

  • @jeffreyeuro6523
    @jeffreyeuro6523 2 роки тому

    How effective would this be to sarcopenia

  • @djanibianco3301
    @djanibianco3301 4 роки тому +2

    What should i study to have a career in gene therapy? Currently i am a bachelor in biotechnology at a small university

  • @valhallanews5675
    @valhallanews5675 3 роки тому +18

    Covid-19 brought me here

    • @dablackxican
      @dablackxican 3 роки тому +2

      Is the vaccines gene therapy? I was doing research and they seem very similar

    • @whyseman375
      @whyseman375 3 роки тому +3

      Yes that vaccine is definitely gene therapy

    • @AccordingToArmon
      @AccordingToArmon 2 роки тому

      Me too smh. The vaccine is gene therapy indeed

    • @TheHeroWhoAsked
      @TheHeroWhoAsked Рік тому

      Maybe I should get another one, I think I have childhood dementia so need that gene therapy 👍👍

  • @TAMOGHNADASBBT
    @TAMOGHNADASBBT 5 років тому +6

    Great video.. what softwares or apps do you use to make such animations? Its so good and detailed..

  • @mohammadzaid1023
    @mohammadzaid1023 10 місяців тому

    In India available any branch agtc

  • @shanavasa3078
    @shanavasa3078 3 роки тому

    Is possible gene therapy for eye optic nerve damage treatment for regeneration..

  • @WaleShozy
    @WaleShozy 2 роки тому

    Can AAV be a possible prognosis for melanoma therapy please???

  • @imanolk5513
    @imanolk5513 3 роки тому +2

    Why would anyone want to get this into their bodies for a viru s that you might get no serious symptoms of. This is more serious than they are showing it to be.

    • @ravenn8600
      @ravenn8600 2 роки тому

      well nobody force you to take gene therapy, some people wanna see better

    • @hunterbiden4975
      @hunterbiden4975 2 роки тому +2

      @@ravenn8600 looks at pfizer mrna "vaccine"

  • @sarahtlm013
    @sarahtlm013 3 роки тому

    How to manufacture the functional gene in labs?

  • @dogemoon5871
    @dogemoon5871 3 роки тому +12

    So im guessing dont question the science behind this at all? K got it

    • @XOXOX4242
      @XOXOX4242 2 роки тому +3

      Yep, just take your jabs every 6 months for the rest of your life & dont question it too much!

    • @Merlin4193
      @Merlin4193 2 місяці тому

      @@XOXOX4242 Dumbass

  • @sharadpatil1837
    @sharadpatil1837 6 років тому

    Is it works on incurable eye disease like stargardt disease ?How many times take this treatment for cure to stargardt or muscular dystrophy.?

  • @sherlinefenelon818
    @sherlinefenelon818 4 роки тому

    which hospital can provide information with gene theraphy my son has terrible x-ald
    i am searching solution

  • @arin5047
    @arin5047 2 роки тому

    Umbrella corps: "that down write that down"

  • @osamasaid2210
    @osamasaid2210 6 років тому

    What type of genes as far u know has a treatment or improvement..

  • @rohanroy6629
    @rohanroy6629 3 роки тому +1

    the revolution of science

  • @melaries1823
    @melaries1823 4 роки тому +1

    I have 22q deletion syndrome which means I dont have the proteins that make cells, which means i have had a cleft palate, speech disorder, neurodevelopmental disorder. Im hoping to get gene therapy soon.

  • @beenishkhalid1224
    @beenishkhalid1224 6 років тому

    What’s success rate for CNGA 3 genes??

  • @alfredlindeborg4736
    @alfredlindeborg4736 7 років тому +5

    Really looking forward to your ACHM studies. I am myself an achromatic that is currently participating in a study to treat the CNGB# ache version.

    • @Kurt_707
      @Kurt_707 7 років тому

      Alfred Lindeborg How is it going?

    • @ilinca9194
      @ilinca9194 7 років тому

      What education did you have to do to become that?

    • @beenishkhalid1224
      @beenishkhalid1224 6 років тому

      Alfred How is it going??is their any progress?

  • @ДокторВадимБондарь

    Very interesting, i was very sceptic about sub retinal injections for gene therapy, i thought it is very traumatic. But after i seen achromatic dog "before" and "äfter"... im very impressed.. thank you

  • @Emily-yt1xx
    @Emily-yt1xx 3 роки тому

    The background music is extremely unneeded and distracting from trying to listen to the narrator. I'm trying to learn this stuff for a class, and I really wish I could turn the music off.

  • @HSAyoub
    @HSAyoub 6 років тому +7

    success rate in clinical trials ?

    • @CaptivaLP
      @CaptivaLP 5 років тому

      HS Ayoub close to 100%. The only problem is, that sometimes mistakes can happen and there isn’t enough research on the safety yet. You meight get cancer from current gene therapy

    • @fireartdrawer9531
      @fireartdrawer9531 4 роки тому

      @@CaptivaLP Use Artificial Intelligent near perfect Robots for operation.

  • @sibu_puhal7255
    @sibu_puhal7255 Рік тому

    I'm muscular atrophy type c patient please help me

  • @maedehdelshad8551
    @maedehdelshad8551 2 роки тому

    I suffer from LCA3 disease and my vision is poor. Can gene therapy help me?

  • @solosailor222
    @solosailor222 4 роки тому +1

    Custom Gene Therapy: engineered from the patient's own cells and CRISPERed to replace faulty code, takes a few million $ in equipment and a team of super experts.
    Available for those who "know someone", and can donate a 10 million dollars to the "researchers".
    For the common folk, "yeah, we're working on it"; means "its not cheap enough yet for YOU"

  • @runsthroughmyveins8
    @runsthroughmyveins8 3 роки тому +8

    covid 19 vax brought me here

    • @dablackxican
      @dablackxican 3 роки тому

      Is the vaccines gene therapy? I was doing research and they seem very similar

  • @surendrachaurasia1047
    @surendrachaurasia1047 6 років тому +1

    Muscular dystrofe treatment bhe ?

  • @maedehdelshad8551
    @maedehdelshad8551 2 роки тому

    suffer from LCA3 disease and my vision is poor. Can gene therapy help me?

  • @waterbird2686
    @waterbird2686 6 років тому

    could it work with neural diseases like SMA ?

    • @Kevin-qy9wf
      @Kevin-qy9wf 6 років тому

      Yes it has shown to work for SMA in mice and a company has already filed for FDA approval . Google "SMA gene therapy mice"

  • @owaisshaikh2144
    @owaisshaikh2144 3 роки тому

    I'm from Pakistan. I have Retinitis Pigmentosa. How can I get treatment?

  • @ashekhinahpt1197
    @ashekhinahpt1197 3 роки тому

    Could a blood transfusion that produces the correct protein cure a mutated gene. And visa versa ?

  • @John-un3lj
    @John-un3lj 5 років тому

    How does it work with alleles? If population X and population Y has different alleles, will gene therapy like this affect them both or is it allele-specific?

  • @user-zf1ti3yg3v
    @user-zf1ti3yg3v 7 років тому +1

    Think also of sicklers, people with sickle cell disease as well, its a red blood cell disease that is like veey common in oill rich region of saudi in eastern province, common and sickle cell like has no real cure so gene therapy of bone marrow is advised

  • @UHFStation1
    @UHFStation1 5 років тому

    Can we not inject proteins instead? Or what if the retina disease isn't due to flawed genes?

  • @enricopetrucci
    @enricopetrucci 8 років тому +2

    33 yo Man with XLRS. Proud of you, guys...

    • @Rswinters1
      @Rswinters1 7 років тому

      Transgenic organisms

  • @jraser2885
    @jraser2885 4 роки тому +2

    Only after reproduction. Reproduction could possible effect dna in ways we will not be able to predict.

  • @itsme477
    @itsme477 6 років тому +10

    please do more New researches using CRISPER for all genes

    • @DTGMRuns
      @DTGMRuns 5 років тому +3

      CRIPSR and gene therapy are separate techniques. Gene therapy involves insertion of fully functional genes for incorporation, while CRISPR edits original nucleotide sequences.

    • @sagudanicasnicas2660
      @sagudanicasnicas2660 5 років тому +3

      CRISPR

  • @melissaalvarado94
    @melissaalvarado94 4 роки тому +2

    Please find a gene therapy for keratoconus 😭 it hurts my eyes so bad 😔

  • @swapnadeepdey9394
    @swapnadeepdey9394 4 роки тому +1

    Wonderful video 😊 loved it

  • @ionescho
    @ionescho Рік тому

    This new gene that is inserted in the cell does not actually integrate itself in the cell's genome right? Otherwise that would be CRISPR-Cas9. The gene sits besides the genome but still has functional benefits but that would mean that the faulty gene would still be able to be passed on to the next generation? Germline editing is still illegal from what I know.

  • @jeepz669
    @jeepz669 4 роки тому

    How rich do I have to be to get this tho??

  • @jakobkirbach7318
    @jakobkirbach7318 5 років тому

    Are the gene modifications inheritable?

    • @louisbroadway4392
      @louisbroadway4392 5 років тому +1

      Jakob Kirbach Good Question!... wanted an answer to this myself

    • @willgreen8310
      @willgreen8310 5 років тому +1

      They wouldn’t be as the transduction is local to the eye. If it was local to the testes then it would be inheritable as the sperm cells would carry the modifications whereas in this case only the cone cells do. Hope this helps.

  • @samuelzev4076
    @samuelzev4076 4 роки тому

    Has this been approved by the FDA?

    • @CrazziiDukuu174
      @CrazziiDukuu174 4 роки тому +1

      Yes it has!

    • @samuelzev4076
      @samuelzev4076 4 роки тому

      @@CrazziiDukuu174 can this cure Myopia?

    • @CrazziiDukuu174
      @CrazziiDukuu174 4 роки тому

      Samuel Christian No. Myopia is basically short sightedness which is corrected by wearing glasses.

    • @samuelzev4076
      @samuelzev4076 4 роки тому

      @@CrazziiDukuu174 but isn’t it also a genetic eror?

  • @mohamedbouacida2722
    @mohamedbouacida2722 4 роки тому

    I have a question
    If genes made the body's proteins, then from where come other body structures such as sugar and fat?

    • @aliyachoudhury8420
      @aliyachoudhury8420 4 роки тому +1

      Fat is not made by the human body, it is stored after ingesting and digesting food. Sugar is made of glucose which is a product of respiration.

  • @dutamulia
    @dutamulia 5 років тому

    the virus is engineered before or after harvesting them, sir?

    • @brainwashedbyevidence948
      @brainwashedbyevidence948 5 років тому

      During... A cell such as hek 239 has the virus genes to make the protein shell...and synthetic DNA is introduced to become enveloped by the protein shell. This is then harvested as the final product.

  • @funny11744
    @funny11744 6 років тому

    I have a genetic mutation on gene ADPRHL2 . Please specify the complementary DNA of mutation :
    ADPRHL2 gene : (NM_017825.2) c.[14C>T];[14C>T] (p.[Ala5Val];[Ala5Val])
    Many thanks. It helps for CRISPR .

  • @immigrantworld4899
    @immigrantworld4899 3 роки тому

    I am color blindness, strong protan since birth. I’ve never experinced full colors since birth and waited the gene therapy since monkeys trial in 2009. I couldn’t cook well, see the sunset, trafic light, match the dress, get dream jobs, and etc. I am fully disable honestly althogh it is not threatining condition. But most scientists dont understand how broken I am. They would rather find the cure of AMD and RP than CVD. In Indonesia said “sampai kapan ini berakhir ya Yesus?” Or in english “till when it will end oh JESUS?” I want to be cured like You ever did for blind people in Yerikho. Yeah, only hope can save my life now.

    • @solyanafekadu
      @solyanafekadu 7 місяців тому

      Everything happen for a reason. Don't feel bad. Even if you can't differ color one day everything will be changed. Be happy.

  • @maeranellarint7060
    @maeranellarint7060 4 роки тому +1

    During gene therapy, we embed one duplicate of a typical allele for each cell that needs it. For what reasons don't we embed an entire chromosome from a sound patient?

    • @usainiyahuza8034
      @usainiyahuza8034 2 роки тому

      #droigiangbe you are the best herbalist online no doubts. After using your herbal medication and getting cured I believed you for life and immediately my trust grew up more for you. I sincerely believe lots of people gonna despise you and blaspheme you for no reasons but they don’t know what they’re missing. You’re a powerful healer of herpes. You be my doctor forevermore for life. I rest my case . contact #droigiangbe on UA-cam'''''

  • @rik-keymusic160
    @rik-keymusic160 3 роки тому +1

    Did I heard that correctly? “Engineered viruses” …

  • @life-kk9xu
    @life-kk9xu 5 років тому

    I just did not understand how you could fix a mutation just by changing one cell. Would its dna take over all the other cells like it?

    • @bodypillow3800
      @bodypillow3800 5 років тому +3

      It's a virus, it duplicates in your cells and spreads to surrounding cells. It eventually infects all the cells and mutates them according to their coding.

    • @life-kk9xu
      @life-kk9xu 5 років тому

      Thanks

  • @nursepurity2955
    @nursepurity2955 7 років тому +1

    I wonder how dey got to know all these

    • @miathapapaya
      @miathapapaya 6 років тому +4

      Years of study on top of decades and decades of other peoples lifetime research. New technological advancements in lab instruments and computers, etc etc.

  • @divyanshu2303
    @divyanshu2303 5 років тому

    Thx ...for concept clear...👍🏻👍🏻

  • @joshireson5457
    @joshireson5457 6 років тому +6

    Now this, this is EPIC!

  • @jacobinvesting5657
    @jacobinvesting5657 2 роки тому +1

    $AGTC, the best stock to BUY right now!

  • @biologyhub94439
    @biologyhub94439 5 років тому +1

    Nice creative video

  • @janisnielson3529
    @janisnielson3529 Рік тому

    I'm grateful to have come across you Dr Igudia youtube, I'm now free after I used the medicine you sent me, having Herpes almost ruined my life but I'm happy today after I used your treatment.

  • @RuralChemist
    @RuralChemist 10 місяців тому +2

    R.I.P AGTC

  • @UHFStation1
    @UHFStation1 5 років тому

    Intellectual property portfolio? In other words you want to monopolize medicine?

  • @تاريخمغربي
    @تاريخمغربي 11 місяців тому

    What about gene therapy after 7 years, or is it just theories and computer graphics?

  • @matthewc4895
    @matthewc4895 6 років тому

    0:09-2:10 Something for me ignore this

  • @oubaybraougui7831
    @oubaybraougui7831 2 роки тому

    their brand name is also the four nucleic bases of DNA

  • @kenw1849
    @kenw1849 2 роки тому

    The music is quite annoying but good video otherwise

  • @melanievidal2578
    @melanievidal2578 4 роки тому

    How genes are inserted into cancer cells ?
    -kindly help me pls 😊

  • @shelbyjenkins1181
    @shelbyjenkins1181 Рік тому +2

    Cool I love it

  • @willankers2426
    @willankers2426 7 років тому +2

    The virus part of this freaks me out

    • @mrdanker6756
      @mrdanker6756 7 років тому

      What's wrong with injecting herpes in your eyes?

    • @pmz558
      @pmz558 6 років тому +2

      Jesus Christ well said Jesus

    • @miathapapaya
      @miathapapaya 6 років тому +5

      Harmless virus. Same as one plant is toxic to eat but another is edible. Both plants, but very different effects on human body.

    • @LightningSe7en
      @LightningSe7en 6 років тому +1

      The risky thing is unless the gene coding is perfected, we could one day cause a doomsday mutation just because a single gene is out of place. *Made a zombie strain. Oopsie!*

  • @adinatalahatova8123
    @adinatalahatova8123 6 років тому

    AGTC is very good, best information, but i cant understand english perfect. (but that okay 👍)

  • @HAZNAUT
    @HAZNAUT 4 роки тому +1

    *if you want a job look for team stellar on facebook, we are starting up, but if you want to study gene therapy with us, i need a big, big science team - we share findings*

  • @azharhussain3849
    @azharhussain3849 4 роки тому

    Wonderful.....,

  • @KortexYTT
    @KortexYTT 4 роки тому +1

    Thank you !

  • @karmand879
    @karmand879 Рік тому

    What happen in now

  • @gomathib2310
    @gomathib2310 3 роки тому

    Dedicated to MicroBiologists,
    Bio Technologists.

  • @MegaDixen
    @MegaDixen 3 роки тому

    this is cool I like this stock

  • @ronbacani3742
    @ronbacani3742 3 роки тому

    STS brought me here.
    Hello BSED Fil2A

  • @uzmaatif3209
    @uzmaatif3209 4 роки тому

    Hi my son 7 years old he is dmd

  • @DouglasJediKnight
    @DouglasJediKnight Рік тому

    All types of sma…not only 1

  • @abhisheksahoo6863
    @abhisheksahoo6863 5 років тому

    Nice expression

  • @vipulaggarwal328
    @vipulaggarwal328 3 роки тому

    Thankyou

  • @Hugo-lu6jg
    @Hugo-lu6jg 6 років тому +1

    its finally happening

  • @techroach6343
    @techroach6343 3 роки тому

    Terrible audio mix.

  • @Heresheis0818
    @Heresheis0818 Рік тому

    2:16👆🏽dementia patients pay me now

  • @zahraiqba765
    @zahraiqba765 7 років тому +1

    Wow👏🏻👏🏻👏🏻

  • @aang7505
    @aang7505 5 років тому +1

    Heroes

  • @typicalrockhound9887
    @typicalrockhound9887 2 роки тому

    💥

  • @Taranjitsingh-qm4pq
    @Taranjitsingh-qm4pq 3 місяці тому

    Damn 🙌

  • @allencompassingevil
    @allencompassingevil 6 років тому

    I want to use this technology to create the first genetic sex change. I could make millions!

  • @ramasharma6113
    @ramasharma6113 6 років тому

    i m suffring lgmd

  • @mathiaspetersen536
    @mathiaspetersen536 6 років тому

    Svend