Now universities are giving graduate degrees in science communication, teaching them graphic design in order to help explain scientific topics! I was amazed at the animation too! It's so rare to find a video that has great explanation and graphics
Joseph, most biomedical animations and animations for commercials production are made in Cinema 4D because of its procedural motion graphics (in c4d it is mograph) package. Also it can be made in Maya 2017-2018, with their motion graphics tool called 'mash'. Besides additional tools are used for rendering (Arnold, Vray etc) and post-production (Photoshop, After Effects). For additional reference or even full models of proteins you can use PDB (protein data bank), all models are free to use; there is addon called mMaya, to install and customize them.
As someone who did his graduation in molecular biology I'm in awe. I remember the first time I saw and realised how mechanistic the inner workings of our cells are. Captivating..
Michael Hurwitz there's the Miller and urey experiment that showed some amino acids could have been generated spontaneously from atmospheric conditions and chemicals present in the early earth atmosphere. Also, you've got molecules (take, RNA) capable of making copies of themselves, while accumulating mutations that makes them susceptible to natural selection. I think that idea is more exciting! Life is.... chemistry and probability. Given the right conditions, and time, it could flourish anywhere. Maybe there's a design... maybe the natural laws of physics in our universe allow this all to happen, and it's pure chance..maybe there's a grand designer who "engineered" the laws of nature to allow life to emerge from nothing. Who knows? The mystery is the most precious part of life... no one knows 😍
According to research,thoughts emerge from neural processes. Humans tend to feel things according to how we perceive information ,so sex has no "feeling" ,science goes deeper than what our brain's process in the 10% that we use. I find it difficult to understand those who say scientific procedures such as hormones can change gender. According to biology,a threadlike structure of nucleic acids and protein found in the nucleus of most living cells, carrying genetic information in the form of genes scientifically determines gender (Chromosomes).Some tend to claim that Crispr DNA can annihilate or mutate chromosomes ,however ,Crispr DNA only binds to the DNA and cuts it, shutting the targeted gene off. The reason why mutating chromosomes or any cell will not be effective is because If you lost a section of DNA in only a single cell or small group of cells, the cells might live as before,and if not they would likely die or be killed due to the deviation. The body has multiple methods of getting rid of problem cells.If the chromosome became misshapen due to the missing DNA, the cellular divison process would break the chromosome and/or cause additional mutations, which would cause one or both cells to die. By stating that , the chromosome that one tried to mutate would only die ,and you would as well due to abnormal occurances and attempts at changing something that scientifically cannot be changed. Many have compared humans to clownfish in such topic as an example,however,in these species, such as many species of coral reef fishes, sex change is a normal anatomical process. . we do not have an anatomical process as they do. Although clownfish can change their physical anatomy , their chromosomes remain as male thoughrought their natural process. -
@@ryanthemainhoee1273 10% use theory is complete fraud, there is no way to calculate percentage of brain, as @Ethan Ferns said, we are using entire brain, some people are smarter, others are dumber. the memory, knowledge portion of brain is anatomically tiny, it is Hypocampus and Amygdala that connects memory to emotions, maybe that's why there is 10% usage theory walking around. On gender changing issue, I completely agree with you, there is no way to change gender by hormones, only way is to replace X to Y or vice versa in all existing cells of person. That's why this thing is called gender dysphoria syndrome, it is psychological problem, like Schizophrenia, Bipolar e.t.c, but of course if you say this in our PC era, you'll be labeled as homophobe e.t.c
Great video. I don't have a background in science but I've been following the press on this topic and feel like this is the first clear explanation I've come across.
CW C I personally believe this is about to be the next huge thing in medicine. Keep an eye on it because it's truly incredible and has the potential to be an absolute game changer
Millions of years of evolution and scientists think they can make genomes better since they learn how to cut it (not very well). Sure. How much damage those "treatments" can and will introduce to the human genomes... I'm writing this from my perspective, I'm in the field on molecular biology for 20+ years.
This is very exciting. Sickle Cell Disease, which primarily affects African-Americans, could be cured using the CRISPR system. I lost my sister a couple years ago after her lifelong fight with SCD and the fact that we now have SCD patients in CRISPR trials brings tears to my eyes. I really do love the power of science.
@@fullercrane1795The only reason why the world is not a better place to live is only because of Adharma. Adharma is our only enemy, Adharma is not any particular person, religion, or race. It lies within ourselves. Adharma includes selfishness, greed, hate etc. Dharma is a notion that shows us the path, it is the concept that says to do what is required of you i.e, do the rightmost thing that needs to be done. You have do it under any circumstances. Do it unattached to the world and everything in it, be it your parents, your emotions, your desires or anything else. It is dharma, a concept, a guiding principle, a conceptualized entity that commands to do what is due to the world, the things that should be done, those things that should be implemented. . By abiding Dharma you always carry out the rightmost action. Adharma is simply not doing the this
The only reason why the world is not a better place to live is only because of Adharma. Adharma is our only enemy, Adharma is not any particular person, religion, or race. It lies within ourselves. Dharma is a notion that shows us the path, it is the concept that says to do what is required of you i.e, do the rightmost thing that needs to be done. You have do it under any circumstances. Do it unattached to the world and everything in it, be it your parents, your emotions, your desires or anything else. It is dharma, a concept, a guiding principle, a conceptualized entity that commands to do what is due to the world, the things that should be done, those things that should be implemented. . By abiding Dharma you always carry out the rightmost action. Adharma is simply not doing the this
As a first year nanobiologist, I do really like the video. It is however wrong on some details, although I think those don't matter too much, considering it is a video for the public. But condensated chromosomes inside the nucleus isn't very accurate, except for if the cell is ready to devide. And all the chromosomes are connected at the middle, also something which isn't always the case. But hey, what do you expect.
Really? Do tell. Other then Crispr being something that was discovered in a bacterial immune system. What is it and not for what they say they use it for. What exactly is it?
@@David-iv6je Never tagged you. Nor do I care about your high school grade mumbling on about grammar. You're as bad as child saying you didnt capitalize a letter. In fact you're worse. You made that stupid remark because you don't want people to know or ask questions. I see no other reason you be that anal over it.
I seriously doubt they will. This is Pandoras box and I do not consent. it must stop. these plus they are also suppressing info on how the technologies generates other mutations.
Better they suppress it than freely release information to people that may use it for malicious purposes. All about finding a balance between publishing enough information to keep the public in the loop and staying safe.
This is similar to computer technologies and mobile communication. At first it will be accessible only to the rich. But after a couple of decades to middle class, and more. And this is a technology that can help to prolong life of all people.
Am certainly not impressed with what people have done. Quiet disappointed in humanity as a whole. As science and technology can help many. There's much more foundational problem's with mountains of lies. The way people react when face the true says it all. In fact youtube is perfect example of this. You can say nothing but facts about race and sex things that go on around the world and it will get removed. Making a more psychotic two faced environment.
The possibilities that Crispr/Cas9 can achieve will be Amazing, spectacular Incredible. We’re at a point where we can unlock our full potential as a species, and what this could bring us (if we use it wisely) I love it
@@healingfrequencycenter8542 You have no idea of our potential either. CRISPR is an interesting concept, and I stand by what I said the fact that it could eliminate diseases as well is proof enough that we should. That being said people would probably use it for something stupid instead of what could actually benefit humankind
Such an amazing animation! I am nowhere near biology and genetics (in fact I'm fom AI), and yet I received some intuitive understanding of how this stuff works! These kind of animations can really help people outside the field intuitively understand the topic. Great for general erudition.
Guys am an engineer, but i learned through videos on youtube that dna is inside each cell and chromosomes are just dna incased for when cells divised and there are 23 pairs of chromosomes each from dad and mom and then there complex proteins that copy / zip / edit / crop dna and that rna and other material is inside the cells (but outside the nucleous of the cell) for those dna operations. I dunno what am saying, but am saying, i learned everything today am trying to get a grip and combine all this new info. Biology is amazing, gonna take this serious.
This makes me wish I understood how interesting bio chemistry can be. I wish i knew this when i was younger. It also makes me think about movies ive watched of advanced xivilazations that have permanently optimized their dna, but end up causing irreversible damage to their species. Which can also be a possibility for us thousands of years from now if we are not careful. Way too interesting of a subject.
@@porter2719 After everyone has had the opportunity to get the vaccine, I hope they unleash the full force of it by spraying it everywhere. That should rid the nation of a lot of morons like you. I know I plan to spread it as much as possible.
@@dinoferrante1718 You want to force experimental medical operations on people against their will, despite not knowing their long term effects. But your definately the good guy because you know whats best for mankind.
Its crazy how even the cutting edge of gene editing isn't actually using proteins designed from scratch but merely repurposed proteins already found in nature. The complexity of life is so overwhelming and vast that it almost feels impossible to fully comprehend for our short lived mortal brains, in many cases we are merely genetic plumbers, discovering kinks and fixing leaks but with very little understanding of how to build or maintain an aqueduct or sewage plant.
Great video! It reminds us to look into biological machinery so as to solve our problems! Natural selection is beyond us when it comes to create biological structures!
@@dareks1193that is covid 😂🤦♂️ You're a host *who brings forth after their kind.. it literally makes bacteria more likely to find the host due to polarity *positive or negative cells even a neutral cell eventually choose sides 🤦♂️ It's legal genocide 🤬
I would be interested to know how CRISPR/Cas9 differs from current gene editing technology. Is it significantly more effective, precise, quicker than other techniques? Or is it the versitility of the system that is the cause for all the hype?
CRISPR-Cas9 essentially *is* current gene editing technology. It's cheaper and faster than previous techniques, though sometimes those tools are still preferable. Generally speaking, what used to take thousands of dollars and months of work can now be accomplished for a few hundred dollars in less than a week.
Previous gene editing techniques had to be engineered to exacting specifications. And each edit you wanted to make required the same lengthy process. Now this single protein, cas9, has the ability to latch onto any guide RNA molecule you care to feed it and you get extremely precise activity.
Compared to TALENs and random mutagenesis it's better in every way. Random mutagenesis in particular (using UV light/chemicals/transposons to induce random mutations) is VERY time consuming so you'd potentially need 10s of thousands of samples to induce random mutations and identify subsequent gene functions.
My mind is blown by the animation😵😱 thank you so much for making this topic understandable and kudos for your hard work especially Mr. Eric Small and Mr. Elizabeth McDonald🙏🙌
In my opinion, it really doesn't matter. In 2018, if you want to alter the human genome, you wouldn't use CRISPR directly on it, it would be much easier to use CRISPR to edit an adenovirus (or similar) vector and then use *that* on the human genome.
In theory yes, but in reality probably not. Still plenty of problems with off target editing, and delivering it efficiently to your cells. If your problem is with a specific organ or tissue, it's more likely. Crossing my fingers for you
sir, it depends, only a few genetic diseases can be cured by crispr till now, kindly tell what type of genetic flaw are you talking about. it depends on that.
Really I hate Science, but when I started to see this types of animation videos I am really fascinating towards Science. Thankyou guys for making learning easy for me.
They do actually. The use cases are plentiful from better healthcare to increased food production and new materials. I don't think this technology is suited to build weapons with it.
you should terrified. China has already opened a human cloning center. They are using crispyr tech to fatten up beagles. did you watch 60 minutes? I did w my parents and they realized the Chinese are doing that to fatten up their food. they eat beagles. do we need to encourage this behavior??? hell no! stop now!
As a 3D artist, I feel it’s awesome to see these types of animations being used in education. Keep up the great work!
Not only the animation is great, but the explanations are the clearest I know of!
What software do you think they used to make this animation?
anndillm ;
Now universities are giving graduate degrees in science communication, teaching them graphic design in order to help explain scientific topics! I was amazed at the animation too! It's so rare to find a video that has great explanation and graphics
Joseph, most biomedical animations and animations for commercials production are made in Cinema 4D because of its procedural motion graphics (in c4d it is mograph) package. Also it can be made in Maya 2017-2018, with their motion graphics tool called 'mash'. Besides additional tools are used for rendering (Arnold, Vray etc) and post-production (Photoshop, After Effects). For additional reference or even full models of proteins you can use PDB (protein data bank), all models are free to use; there is addon called mMaya, to install and customize them.
As someone who did his graduation in molecular biology I'm in awe.
I remember the first time I saw and realised how mechanistic the inner workings of our cells are. Captivating..
I feel the same way! It's inspiring and exhilarating isn't it 😍
Michael Hurwitz there's the Miller and urey experiment that showed some amino acids could have been generated spontaneously from atmospheric conditions and chemicals present in the early earth atmosphere. Also, you've got molecules (take, RNA) capable of making copies of themselves, while accumulating mutations that makes them susceptible to natural selection. I think that idea is more exciting! Life is.... chemistry and probability. Given the right conditions, and time, it could flourish anywhere. Maybe there's a design... maybe the natural laws of physics in our universe allow this all to happen, and it's pure chance..maybe there's a grand designer who "engineered" the laws of nature to allow life to emerge from nothing. Who knows? The mystery is the most precious part of life... no one knows 😍
According to research,thoughts emerge from neural processes. Humans tend to feel things according to how we perceive information ,so sex has no "feeling" ,science goes deeper than what our brain's process in the 10% that we use.
I find it difficult to understand those who say scientific procedures such as hormones can change gender. According to biology,a threadlike structure of nucleic acids and protein found in the nucleus of most living cells, carrying genetic information in the form of genes scientifically determines gender (Chromosomes).Some tend to claim that Crispr DNA can annihilate or mutate chromosomes ,however ,Crispr DNA only binds to the DNA and cuts it, shutting the targeted gene off. The reason why mutating chromosomes or any cell will not be effective is because If you lost a section of DNA in only a single cell or small group of cells, the cells might live as before,and if not they would likely die or be killed due to the deviation. The body has multiple methods of getting rid of problem cells.If the chromosome became misshapen due to the missing DNA, the cellular divison process would break the chromosome and/or cause additional mutations, which would cause one or both cells to die. By stating that , the chromosome that one tried to mutate would only die ,and you would as well due to abnormal occurances and attempts at changing something that scientifically cannot be changed. Many have compared humans to clownfish in such topic as an example,however,in these species, such as many species of coral reef fishes, sex change is a normal anatomical process. . we do not have an anatomical process as they do. Although clownfish can change their physical anatomy , their chromosomes remain as male thoughrought their natural process. -
@@ryanthemainhoee1273 10% use theory is complete fraud, there is no way to calculate percentage of brain, as @Ethan Ferns said, we are using entire brain, some people are smarter, others are dumber. the memory, knowledge portion of brain is anatomically tiny, it is Hypocampus and Amygdala that connects memory to emotions, maybe that's why there is 10% usage theory walking around.
On gender changing issue, I completely agree with you, there is no way to change gender by hormones, only way is to replace X to Y or vice versa in all existing cells of person. That's why this thing is called gender dysphoria syndrome, it is psychological problem, like Schizophrenia, Bipolar e.t.c, but of course if you say this in our PC era, you'll be labeled as homophobe e.t.c
✋✋
This was the most calming academic video I have ever watched
Not if you're watching it in 2021.
@@Dreadandcircuses hahahahahahahahaha what a deep say
Yeah
You should check the secret life of gymnosperms, angiosperms. And mosses. Watched them for Botany and they were hilariously great, but also soothing
Great video. I don't have a background in science but I've been following the press on this topic and feel like this is the first clear explanation I've come across.
CW C I personally believe this is about to be the next huge thing in medicine. Keep an eye on it because it's truly incredible and has the potential to be an absolute game changer
Millions of years of evolution and scientists think they can make genomes better since they learn how to cut it (not very well). Sure. How much damage those "treatments" can and will introduce to the human genomes... I'm writing this from my perspective, I'm in the field on molecular biology for 20+ years.
@@mickjagger149 i suffering polycystic kidney disease by mutations /genetic I keep on eyes and hope if it will bring in our life ameen
Exactly
Wow, I was pleasantly surprised by the high quality of this video. Keep up the great work!!
This is very exciting. Sickle Cell Disease, which primarily affects African-Americans, could be cured using the CRISPR system. I lost my sister a couple years ago after her lifelong fight with SCD and the fact that we now have SCD patients in CRISPR trials brings tears to my eyes. I really do love the power of science.
It's amazing right? The CRISPR Cas9 gene editing technique could be used to potentially cure all genetically linked diseases from the fetus!
Science wont sort out the African American issue.
@@fullercrane1795The only reason why the world is not a better place to live is only because of Adharma.
Adharma is our only enemy, Adharma is not any particular person, religion, or race. It lies within ourselves. Adharma includes selfishness, greed, hate etc.
Dharma is a notion that shows us the path, it is the concept that says to do what is required of you i.e, do the rightmost thing that needs to be done. You have do it under any circumstances. Do it unattached to the world and everything in it, be it your parents, your emotions, your desires or anything else. It is dharma, a concept, a guiding principle, a conceptualized entity that commands to do what is due to the world, the things that should be done, those things that should be implemented.
.
By abiding Dharma you always carry out the rightmost action.
Adharma is simply not doing the this
The only reason why the world is not a better place to live is only because of Adharma.
Adharma is our only enemy, Adharma is not any particular person, religion, or race. It lies within ourselves.
Dharma is a notion that shows us the path, it is the concept that says to do what is required of you i.e, do the rightmost thing that needs to be done. You have do it under any circumstances. Do it unattached to the world and everything in it, be it your parents, your emotions, your desires or anything else. It is dharma, a concept, a guiding principle, a conceptualized entity that commands to do what is due to the world, the things that should be done, those things that should be implemented.
.
By abiding Dharma you always carry out the rightmost action.
Adharma is simply not doing the this
You'll be happy to know they successfully treated it with crispr in 2023
Speaking as a molecular biologist, this is a great video. Explains clearly without introducing errors!
As a first year nanobiologist, I do really like the video. It is however wrong on some details, although I think those don't matter too much, considering it is a video for the public. But condensated chromosomes inside the nucleus isn't very accurate, except for if the cell is ready to devide. And all the chromosomes are connected at the middle, also something which isn't always the case. But hey, what do you expect.
@@thatyougoon1785 Simplifying for clarity. Perfect is often the enemy of good, especially with clear presentation.
Really? Do tell. Other then Crispr being something that was discovered in a bacterial immune system. What is it and not for what they say they use it for. What exactly is it?
@@fullercrane1795 First you use "then" inappropriately, followed by a syntactic jumble. Are you asking a question?
@@David-iv6je
Never tagged you. Nor do I care about your high school grade mumbling on about grammar. You're as bad as child saying you didnt capitalize a letter. In fact you're worse. You made that stupid remark because you don't want people to know or ask questions. I see no other reason you be that anal over it.
I truly hope that humanity will fully comprehend the responsibility that comes with using this kind of technology.
I seriously doubt they will. This is Pandoras box and I do not consent. it must stop. these plus they are also suppressing info on how the technologies generates other mutations.
Better they suppress it than freely release information to people that may use it for malicious purposes. All about finding a balance between publishing enough information to keep the public in the loop and staying safe.
You guys are idiots! Fuck the mutation! This stuff needs to be researched and if proven safe it can help people with many different types of diseases.
DatMan Dooley only problem is when they do find out whatever with this... It'll only be accessible to the rich. But I agree with you
This is similar to computer technologies and mobile communication. At first it will be accessible only to the rich. But after a couple of decades to middle class, and more.
And this is a technology that can help to prolong life of all people.
Having just read Jennifer Doudna's book "A crack in creation", this sort of video helps bring the science alive. Well done.
perfect for teaching my class. By far the best CRSIPR explanation video I have found, and I have looked at about 20 of them!!!
I am definitely impressed with the accomplishments of our species! Marvelous work!!
Am certainly not impressed with what people have done. Quiet disappointed in humanity as a whole. As science and technology can help many. There's much more foundational problem's with mountains of lies. The way people react when face the true says it all. In fact youtube is perfect example of this. You can say nothing but facts about race and sex things that go on around the world and it will get removed. Making a more psychotic two faced environment.
This is stunning. The brilliance of the researchers is beyond my comprehension.
The possibilities that Crispr/Cas9 can achieve will be Amazing, spectacular Incredible. We’re at a point where we can unlock our full potential as a species, and what this could bring us (if we use it wisely) I love it
lol you have no idea of our potential and they don't want you to know just so you can rely on these artificial means of playing God
@@healingfrequencycenter8542 if it can eliminate diseases then why not utilize it?
@@healingfrequencycenter8542 You have no idea of our potential either. CRISPR is an interesting concept, and I stand by what I said the fact that it could eliminate diseases as well is proof enough that we should. That being said people would probably use it for something stupid instead of what could actually benefit humankind
@@healingfrequencycenter8542 it can cure diseases, that’s potential. What ideas can you offer to progress mankind?
This is the clearest explanation of the CRISPR-Cas9 system I've seen to date.
Extraordinary animations! Thank you for this piece. Very interesting.
I'm overwhelmed by their mode of action. Splendid animation
Such an amazing animation! I am nowhere near biology and genetics (in fact I'm fom AI), and yet I received some intuitive understanding of how this stuff works! These kind of animations can really help people outside the field intuitively understand the topic. Great for general erudition.
Guys am an engineer, but i learned through videos on youtube that dna is inside each cell and chromosomes are just dna incased for when cells divised and there are 23 pairs of chromosomes each from dad and mom and then there complex proteins that copy / zip / edit / crop dna and that rna and other material is inside the cells (but outside the nucleous of the cell) for those dna operations.
I dunno what am saying, but am saying, i learned everything today am trying to get a grip and combine all this new info. Biology is amazing, gonna take this serious.
O vídeo está perfeito, certamente tornará mais fácil a aprendizagem para os alunos de BIOMOL
Give the animator a raise and a trophy 🏆 that was so well done and thoroughly explained 👏
Clear, concise explanation of a difficult topic👍🏼
Good videos like this are hard to find, please continue to produce more.
This makes me wish I understood how interesting bio chemistry can be. I wish i knew this when i was younger. It also makes me think about movies ive watched of advanced xivilazations that have permanently optimized their dna, but end up causing irreversible damage to their species. Which can also be a possibility for us thousands of years from now if we are not careful. Way too interesting of a subject.
Fantastic animations. Learning is fun with these videoclips. Thanks to all the authors of these great art
The fact that we can visualize such mechanisms is so amazing!
“DharmaCON” is likely the most important thing needed to be known here
Wow! What a powerful use of animation! That's very impressive!
Wow.. everything is clearly explained in just a few minutes. Very impressive and helpful.
The ease that this can be done should actually terrifying to the human race. Imagine this in the hands of someone with less than good intentions.
Like Bill Gates and Fauci?
@@porter2719 After everyone has had the opportunity to get the vaccine, I hope they unleash the full force of it by spraying it everywhere. That should rid the nation of a lot of morons like you. I know I plan to spread it as much as possible.
@@dinoferrante1718 are you one of those people with less than good intentions?
@@someguy8273 No. I'm trying to save the human race in spite of the morons.
@@dinoferrante1718 You want to force experimental medical operations on people against their will, despite not knowing their long term effects. But your definately the good guy because you know whats best for mankind.
Best video on CRISPR I have seen so far.
This is a great animation and very understandable thank you for this creation!!!
Dude, the video is way too calming!
crispr is bettr than tumblr
lol
But tumblr is funnyr than crispr...but you have to admit...crispr is a lot cooler than tumblr
tumblr causes cancer, crispr gets rid of it
does CRISPR allows porn tho??
@@AxelZaore depending on the gene you knock-out/down/in, the mice can probably stay fertile afterwards
This was beautiful and easy to understand! props to the animators
watched this yesterday, and i can't understand shit. Now im fuckin stoned, I can even understand the whole universe.
Man…
Its crazy how even the cutting edge of gene editing isn't actually using proteins designed from scratch but merely repurposed proteins already found in nature. The complexity of life is so overwhelming and vast that it almost feels impossible to fully comprehend for our short lived mortal brains, in many cases we are merely genetic plumbers, discovering kinks and fixing leaks but with very little understanding of how to build or maintain an aqueduct or sewage plant.
Great video! It reminds us to look into biological machinery so as to solve our problems! Natural selection is beyond us when it comes to create biological structures!
Reverting nature or die this is all we need
This was a piece of art! Subscribed. Great work
This method has been applied in covid mRNA vaccines
Yes to edit and DNA
And killed many people
@@rogerbenito595 and to generate antibodies.
very exciting to know science is evolving to more advance methods that can be used to cure disease 🙏🏼🙏🏼
Finally,
I learned how CRISPR Cas9 works
Thank you for helping me
شكراً من القلب أفضل شرح شاهدة على الإطلاق 🌹🌹
This animation is awesome! CRISPR-CAS9 system is really interesting! I hope we can utilize more biotechnology tools.
Standards still Maintained. No one can replace THE NATURE...really love it❤❤❤❤.
the nature is so inttelgent man
Anyone after Nobel Prize in chemistry 2020 ?
Meeee
Mee
I knew it before the nobel but underestimated its value
@whesley hynes i appreciate!
@whesley hynes you have no idea what you are talking about do you?
I wrote a speech about crispr for biology last year. This is extremely interesting stuff
I love your work, as a regular citizen and science enthusiast, it´s a perfect way to understand such complex processes
BRAVO, IT IS AN AMAZING ANIMATION OF THE CONCEPT, PLEASE KEEP IT UP...👍🏼
This was mind blowing. So much good and bad that can arise from this.
I was just googling this for a paper and now this is in my recommendations. Google works fast 😅
Personally, I'd prefer to keep my natural DNA.
Ok...
its for genetic disorders
@@ooglemoogle8210 for covid also .
You can get a superpower
@@dareks1193that is covid 😂🤦♂️
You're a host *who brings forth after their kind.. it literally makes bacteria more likely to find the host due to polarity *positive or negative cells even a neutral cell eventually choose sides 🤦♂️
It's legal genocide 🤬
These visuals are much better than the helix, sheets and folders that you're given in text books or shown in presentations.
Will change everything...
Still waiting
Please make a video on Cre Lox system. It will be better understood if visualised and help many people. Seeing is believing
Is there any good text or resources to study more about this topic. If you know then please help?
Rajinder Singh Bump. Would also appreciate this.
We've compiled a lot of resources (including this one!) on our website - innovativegenomics.org/resources/educational-materials/
You can play with CRISPr www.the-odin.com/diy-crispr-kit/
Great video about the application of Crisper! Really inspiring!
Don't let them fool you, its not about tackling diseases, its about transhumanism and connecting humans with artificial intelligence.
Still absolutely amazing every time I watch it
I would be interested to know how CRISPR/Cas9 differs from current gene editing technology. Is it significantly more effective, precise, quicker than other techniques? Or is it the versitility of the system that is the cause for all the hype?
Julius Stopforth the sgRNA @0:42 can be designed by researcher to complement with a specific sequence in the genome that researchers want to modify
CRISPR-Cas9 essentially *is* current gene editing technology. It's cheaper and faster than previous techniques, though sometimes those tools are still preferable. Generally speaking, what used to take thousands of dollars and months of work can now be accomplished for a few hundred dollars in less than a week.
Previous gene editing techniques had to be engineered to exacting specifications. And each edit you wanted to make required the same lengthy process. Now this single protein, cas9, has the ability to latch onto any guide RNA molecule you care to feed it and you get extremely precise activity.
Short answer: Yes.
Compared to TALENs and random mutagenesis it's better in every way. Random mutagenesis in particular (using UV light/chemicals/transposons to induce random mutations) is VERY time consuming so you'd potentially need 10s of thousands of samples to induce random mutations and identify subsequent gene functions.
Absolutely well done and definitely keep it up!!! 👍👍👍👍👍
What's this beautiful music?
U simp
Proud to know my loved one is working on this at Carnegie Mellon University! Super cool stuff. Totally over my head!
@whesley hynes maybe you need to watch this video again....or read a book. Get a grip kiddo.
@whesley hynes Damn Karen. Maybe start educating yourself before you comment stupid things like this.
@whesley hynes you’re really convincing me
@whesley hynes We should stop hitler, call some organizations for us and get the ball rolling!
@whesley hynes yeah, searching for cures to deadly diseases and genetic engineering is totally wicked dude
Tribute to Jennifer Doudna and Emmanuelle Charpentier❤️💐✨
I love the background theme haha, also, thanks for this overview, great starting point to research CRISPR applications.
tutorial pls i want glow in the dark hair
mellow m your offspring (child) will have the effect not you.
Bigbanana E hair is dead cells though, is it not?
@@liljimbob8740 no, it's just protein.
@@liljimbob8740 hair is composed of keratin, the very same protein that is present in dead skin cells
Myr Na interesting. Thank you.
My mind is blown by the animation😵😱 thank you so much for making this topic understandable and kudos for your hard work especially Mr. Eric Small and Mr. Elizabeth McDonald🙏🙌
i wonder how criper does access the DNA sequence when it's in form of euchromatin, packed and covered in histones..
Nereus during replication and transcription DNA unwound from the compact chromosomal conformation, and that's the window when CRISPR works...
In my opinion, it really doesn't matter. In 2018, if you want to alter the human genome, you wouldn't use CRISPR directly on it, it would be much easier to use CRISPR to edit an adenovirus (or similar) vector and then use *that* on the human genome.
@@kropotkln ? You get crispr into cells using viruses
This video is a link added to my i-Text for Cell Biology - incredible!
Layman's question. I was born with a genetic flaw that has caused me problems now that I am almost 50 years old. Can CRISPR tech help me?
In theory yes, but in reality probably not. Still plenty of problems with off target editing, and delivering it efficiently to your cells. If your problem is with a specific organ or tissue, it's more likely. Crossing my fingers for you
sir, it depends, only a few genetic diseases can be cured by crispr till now, kindly tell what type of genetic flaw are you talking about. it depends on that.
I love to watch science animations ❤️❤️❤️
I love advanced technologies in foreign countries 🙏🌎🙏
oh my god, i had never seen such a pretty chromosome, these animations are so good
The mind boggles at how far we have come and how much further we are yet to travel. Fascinating.
youre going backward not forward if you think this is the way forward
Eugenics?
C-19 vaccines
@@unmu1392 ur mom
Genetics engineering is not bad unless it is only used by the elites
What a gorgeous animation! Thank you
Who’s here after buying crisper stock 🤣?
OMG! This is so beautiful;)👍
Padora's box?
Superbly done thank you sooo much for this video 🙏
Hmm why is this in my recommended? The Ai algorithm knows what this Rona vaccine is..do you?
GREAT video!! Inspiring!! Thank you!!
what is the name of the background music? i really need to know
This is a great breakthrugh of science.
All I see are wads of gum.
We must use these kind of things in a educational level
i understood maybe 30% of what I just watched
Really I hate Science, but when I started to see this types of animation videos I am really fascinating towards Science. Thankyou guys for making learning easy for me.
NIGHT OF THE LIVING DEAD...
Very interesting video! And thanks a lot for the English subtitle!
I'd feel better about all this, if I thought they had our best interests at heart.
They do actually. The use cases are plentiful from better healthcare to increased food production and new materials. I don't think this technology is suited to build weapons with it.
Susan Raezer: How many times have you done something with their "best interest at heart" and have it totally backfired on you...? Be honest!!!
you should terrified. China has already opened a human cloning center.
They are using crispyr tech to fatten up beagles. did you watch 60 minutes? I did w my parents and they realized the Chinese are doing that to fatten up their food. they eat beagles. do we need to encourage this behavior??? hell no! stop now!
The animation is amazing work!
God is amazing and imagine what's in store for you if you are truly saved by the Son of God Jesus Christ who is God the Father.
Jesus is the real demon 😈
All of this is so insanely cool
Crazy scientists are playing roulette russe with our lives and think our DNA is some kind of logo play.
stupid its for curing genetic defects u idoit
Incredible and breath-taking.
very dangerous stuff
how
This is a great animation! Thank you
You've got to be out of your mind if would think all of these systems are as a result of time+mutation.
The CRISPR system evolved in bacteria as a defense mechanism against viruses (so they could target viral DNA sequences and disable them).
So just because we cant explain it all now, a God have to had made it? Just a matter of time before they can explain more
Great video. Easy to understand!
Read Robison pathology can't understood!! Watched yours!! Concept Cleared
The animations and background music just remind me of an RPG character customizer
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