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Gene Therapy Explained
Many diseases have a genetic basis, which means that the disease is caused by mutated genes which provide incorrect instructions that cause the cell to produce abnormal protein, or disable production of the protein completely.
In gene therapy, a functional copy of the gene is delivered into a patient’s own cells. Normal protein that is produced from a functional gene corrects the underlying cause of the disease, and may provide restorative disease-modifying effects.
Gene therapy uses engineered viruses to deliver genes into cells, such as adeno-associated virus (AAV) vectors, which are especially well suited for treating retinal diseases. Genetic defects in the eye can cause vision loss or blindness, and gene therapy can provide a long-term therapeutic benefit.
This video explains how gene therapy, delivered by AAV vectors, works.
For more info, visit www.agtc.com.
Переглядів: 468 501

Відео

Foundation Park: a Home for Life Science Innovation in North Central Florida
Переглядів 1 тис.8 років тому
In February 2016, AGTC announced the opening of a new combined use corporate office and laboratory facility in the rapidly growing North Central Florida biotech corridor. The facility is located within Foundation Park in Alachua County, Florida. Listen to AGTC CEO Sue Washer and Mark Long, director of the Sid Martin Biotechnology Incubator at the University of Florida, discuss the relationship ...
Sheep with Achromatopsia Are Able to Navigate a Maze After Gene Therapy
Переглядів 3,3 тис.9 років тому
Sheep affected by achromatopsia (a genetic cause of blindness) are dramatically better able to navigate a maze after receiving gene therapy. For each animal, you see its ear tag before treatment and its poor performance navigating the maze. Then, you see the same sheep (ear tag shown again) after treatment (in just one eye) showing markedly improved performance; actually very nearly normal. Thi...
About the University of Florida Office of Technology Licensing
Переглядів 2749 років тому
The University of Florida Office of Technology Licensing’s mission is to help transfer University of Florida discoveries from the laboratory towards the market, in order to make the world a better place. AGTC is proud of our origins as a UF-based startup. See how the UF OTL works with companies such as AGTC to foster innovation & success.
Michigan State University, UPenn and AGTC’s Gene Therapy Proof-of-Concept for Achromatopsia
Переглядів 4,6 тис.9 років тому
CNGB3- Achromatopsia is caused by a gene mutation that results in extremely poor visual acuity, photophobia, day blindness and complete loss of color discrimination. It affects dogs as well as humans. Using gene therapy to deliver correct copies of the causative gene, veterinary ophthalmology researchers from the University of Pennsylvania and Michigan State University are successfully treating...
AGTC CEO Sue Washer's Presentation at the ARM's 3rd Annual Regen Med Investor Day
Переглядів 3109 років тому
Sue Washer, AGTC President and CEO, provided a company presentation at the Alliance for Regenerative Medicine's 3rd Annual Regen Med Investor Day in which she discussed key corporate milestones and provided an update on AGTC’s clinical pipeline. This presentation took place on March 25, 2015.
AGTC’s Technology
Переглядів 6669 років тому
How does AGTC's gene therapy work? Find out from our experts.
AGTC speaks with OIS Co-Chair Gil Kliman at the OIS@AAO Innovator Award Presentation
Переглядів 1609 років тому
AGTC CEO Sue Washer, after winning the OIS@AAO Innovator award, sits down with Dr. Bill Hauswirth and OIS Co-Chair Gil Kliman to discuss AGTC’s technology and role in the gene therapy industry.
AGTC’s Sue Washer on Ophthalmology IPOs
Переглядів 2189 років тому
AGTC CEO, Sue Washer, speaks with fellow CEOs about ophthalmology IPOs.
AGTC’s Sue Washer featured on The Corridor Magazine’s Faces of Technology
Переглядів 3949 років тому
Sue Washer speaks to The Corridor Magazine, a publication of The Florida High Tech Council, about innovation at AGTC
AGTC Technology’s Effect on Canines
Переглядів 2159 років тому
Watch the effect AGTC's gene therapy technology has on a canine.
AGTC Company Overview
Переглядів 2,5 тис.9 років тому
Learn about AGTC, what we do, and our focus on rare diseases.
AGTC: A Great Place To Work
Переглядів 1,1 тис.9 років тому
What makes AGTC a great place to work? Hear from our team about why they love working at AGTC.

КОМЕНТАРІ

  • @Taranjitsingh-qm4pq
    @Taranjitsingh-qm4pq 3 місяці тому

    Damn 🙌

  • @henriquetrindade6483
    @henriquetrindade6483 8 місяців тому

    My son is 13yrs old and he has retinitis pigmentosa

  • @henriquetrindade6483
    @henriquetrindade6483 8 місяців тому

    Hello...is it fine for those who has retinitis pigmentosa??

  • @Dharmendrakumar-vi4kb
    @Dharmendrakumar-vi4kb 9 місяців тому

    Agtc company kaisa hai

  • @RuralChemist
    @RuralChemist 10 місяців тому

    R.I.P AGTC

  • @mohammadzaid1023
    @mohammadzaid1023 10 місяців тому

    In India available any branch agtc

  • @تاريخمغربي
    @تاريخمغربي 11 місяців тому

    What about gene therapy after 7 years, or is it just theories and computer graphics?

  • @Zzz21140
    @Zzz21140 Рік тому

    Explained really well

  • @janisnielson3529
    @janisnielson3529 Рік тому

    I'm grateful to have come across you Dr Igudia youtube, I'm now free after I used the medicine you sent me, having Herpes almost ruined my life but I'm happy today after I used your treatment.

  • @sibu_puhal7255
    @sibu_puhal7255 Рік тому

    I'm muscular atrophy type c patient please help me

  • @aleksandarculjic1640
    @aleksandarculjic1640 Рік тому

    All we need now is one of those virus things. Which don't grow on trees... ua-cam.com/video/Q8chs2ncYIw/v-deo.html

  • @karmand879
    @karmand879 Рік тому

    What happen in now

  • @Heresheis0818
    @Heresheis0818 Рік тому

    2:16👆🏽dementia patients pay me now

  • @DouglasJediKnight
    @DouglasJediKnight Рік тому

    All types of sma…not only 1

  • @shelbyjenkins1181
    @shelbyjenkins1181 Рік тому

    Cool I love it

  • @ionescho
    @ionescho Рік тому

    This new gene that is inserted in the cell does not actually integrate itself in the cell's genome right? Otherwise that would be CRISPR-Cas9. The gene sits besides the genome but still has functional benefits but that would mean that the faulty gene would still be able to be passed on to the next generation? Germline editing is still illegal from what I know.

  • @randalramsook5445
    @randalramsook5445 Рік тому

    Covid 19 shot is gene therapy.

  • @kenw1849
    @kenw1849 2 роки тому

    The music is quite annoying but good video otherwise

  • @maedehdelshad8551
    @maedehdelshad8551 2 роки тому

    I suffer from LCA3 disease and my vision is poor. Can gene therapy help me?

  • @maedehdelshad8551
    @maedehdelshad8551 2 роки тому

    suffer from LCA3 disease and my vision is poor. Can gene therapy help me? 

  • @LoveLove-ur8qx
    @LoveLove-ur8qx 2 роки тому

    I was able to sort out my herpes virus from my body system completely after using #drehimen herbal remedy ...

  • @jacobinvesting5657
    @jacobinvesting5657 2 роки тому

    $AGTC, the best stock to BUY right now!

  • @jacobinvesting5657
    @jacobinvesting5657 2 роки тому

    $AGTC, the best stock to BUY right now!

  • @arin5047
    @arin5047 2 роки тому

    Umbrella corps: "that down write that down"

  • @beautiful3089
    @beautiful3089 2 роки тому

    Thats very bad. They gonna change cell molecule but they d not mention that each of them has sound vibration phantom code and if u change cell molecule- the phantome u cant change which gonna prove u cant play a God. They r just ssadists doing experiments on people. We gonna see soon ugly creatures coming off those mutations.

  • @usainiyahuza8034
    @usainiyahuza8034 2 роки тому

    #droigiangbe you are the best herbalist online no doubts. After using your herbal medication and getting cured I believed you for life and immediately my trust grew up more for you. I sincerely believe lots of people gonna despise you and blaspheme you for no reasons but they don’t know what they’re missing. You’re a powerful healer of herpes. You be my doctor forevermore for life. I rest my case . contact #droigiangbe on UA-cam'''''

  • @oubaybraougui7831
    @oubaybraougui7831 2 роки тому

    their brand name is also the four nucleic bases of DNA

  • @czekoladowyzajunc41
    @czekoladowyzajunc41 2 роки тому

    Thank you so much for making this video! I’m so glad sheep with achromatopsia are finally getting some media representation. Please say hi to them from me. I find their perseverance extremely inspiring. It gives me hope that maybe one day I will be able to successfully navigate a maze just like them!

  • @jeffreyeuro6523
    @jeffreyeuro6523 2 роки тому

    How effective would this be to sarcopenia

  • @typicalrockhound9887
    @typicalrockhound9887 2 роки тому

    💥

  • @WaleShozy
    @WaleShozy 2 роки тому

    Can AAV be a possible prognosis for melanoma therapy please???

  • @ДокторВадимБондарь

    Very interesting, i was very sceptic about sub retinal injections for gene therapy, i thought it is very traumatic. But after i seen achromatic dog "before" and "äfter"... im very impressed.. thank you

  • @rik-keymusic160
    @rik-keymusic160 3 роки тому

    Did I heard that correctly? “Engineered viruses” …

  • @imanolk5513
    @imanolk5513 3 роки тому

    Why would anyone want to get this into their bodies for a viru s that you might get no serious symptoms of. This is more serious than they are showing it to be.

    • @ravenn8600
      @ravenn8600 2 роки тому

      well nobody force you to take gene therapy, some people wanna see better

    • @hunterbiden4975
      @hunterbiden4975 2 роки тому

      @@ravenn8600 looks at pfizer mrna "vaccine"

  • @yesmate78
    @yesmate78 3 роки тому

    The so called va ccine

  • @Emily-yt1xx
    @Emily-yt1xx 3 роки тому

    The background music is extremely unneeded and distracting from trying to listen to the narrator. I'm trying to learn this stuff for a class, and I really wish I could turn the music off.

  • @immigrantworld4899
    @immigrantworld4899 3 роки тому

    Gene therapy for red green color blindness please😭

  • @kr-1543
    @kr-1543 3 роки тому

    Cobid 19 Vaxine. (Misspelled for obvious reasons)

  • @yeshwanthreddy268
    @yeshwanthreddy268 3 роки тому

    UA-cam have dh12 gene mutation so I can participate in clinical trial I am staying in India CEO at present there is any treatment for th 12 gene mutation

  • @trojanhell7639
    @trojanhell7639 3 роки тому

    That’s what they use for COVID VACCINES loool Even MODERNA filings shows FDA recognize it as GENE THERAPY that means it’s like what they use for cancer patient it’s nothing more then a TYLENOL 🤣🤣🤣🤣 This sh$t doesn’t stop the spread, doesn’t stop infection or create immunity 😂 they probably messed around with people Genes in their dna

  • @ashekhinahpt1197
    @ashekhinahpt1197 3 роки тому

    Could a blood transfusion that produces the correct protein cure a mutated gene. And visa versa ?

  • @jerrynemec930
    @jerrynemec930 3 роки тому

    Like a vax that makes a cell grow a spike so the body will make antibodies to fight the spike ?

    • @imanolk5513
      @imanolk5513 3 роки тому

      Isn't easier to inject the spike in the vax instead of making the body produce it?

  • @Tokiofritz
    @Tokiofritz 3 роки тому

    Is this why the MRNA vaccine is described as 'synthetic'? There's no actual viral sample involved? Complete layman, here!

  • @vipulaggarwal328
    @vipulaggarwal328 3 роки тому

    Thankyou

  • @sarahtlm013
    @sarahtlm013 3 роки тому

    How to manufacture the functional gene in labs?

  • @ronbacani3742
    @ronbacani3742 3 роки тому

    STS brought me here. Hello BSED Fil2A

  • @shanavasa3078
    @shanavasa3078 3 роки тому

    Is possible gene therapy for eye optic nerve damage treatment for regeneration..

  • @techroach6343
    @techroach6343 3 роки тому

    Terrible audio mix.

  • @immigrantworld4899
    @immigrantworld4899 3 роки тому

    I am color blindness, strong protan since birth. I’ve never experinced full colors since birth and waited the gene therapy since monkeys trial in 2009. I couldn’t cook well, see the sunset, trafic light, match the dress, get dream jobs, and etc. I am fully disable honestly althogh it is not threatining condition. But most scientists dont understand how broken I am. They would rather find the cure of AMD and RP than CVD. In Indonesia said “sampai kapan ini berakhir ya Yesus?” Or in english “till when it will end oh JESUS?” I want to be cured like You ever did for blind people in Yerikho. Yeah, only hope can save my life now.

    • @solyanafekadu
      @solyanafekadu 7 місяців тому

      Everything happen for a reason. Don't feel bad. Even if you can't differ color one day everything will be changed. Be happy.

  • @anthonydonald7644
    @anthonydonald7644 3 роки тому

    draziegbe1 has really made me So much believe in him by getting me cured From my herpes virus with his herbal Medicine, thank you very much draziegbe1 on UA-cam..