PCR - Polymerase Chain Reaction (IQOG-CSIC)

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  • Опубліковано 19 сер 2024
  • PCR technique (Polymerase Chain Reaction), Animation.
    It is a technique used to make multiple copies of a DNA segment of interest, generating a large amount of copies from a small initial simple.
    Amplification of DNA segments makes possible the detection of pathogenic virus or bacteria, identification of individuals (DNA fingerprinting), and several scientific research involving DNA manipulation.
    Spanish version: • PCR: Reacción en Caden...
    This video has been produced in the Institute of General Organic Chemistry of the CSIC (IQOG-CSIC), Spain, by Guillermo Corrales, as part of its task for promoting Science Communication and may be freely used for educational and science popularization purposes.
    Canal Divulgación. Divulgación científica.
    Instituto de Química Orgánica General (QOG) CSIC
    Madrid, Spain
    / canaldivulgacion

КОМЕНТАРІ • 1,7 тис.

  • @slabon6091
    @slabon6091 2 роки тому +711

    the music makes me feel like if i dont learn this the world is gonna end or something

  • @tomtran5643
    @tomtran5643 7 років тому +2325

    Learning about DNA has never been more epic.

  • @Michaelbsav707
    @Michaelbsav707 3 роки тому +30

    I can never forget this solely due to the magnificent grammy-level soundtrack

  • @lazizasamov440
    @lazizasamov440 5 місяців тому +33

    That’s the most dramatic PCR ever

  • @aldurocher
    @aldurocher 7 років тому +539

    This is the kind of PCR explanation I've been searching for my whole life. Thanks so much.

    • @PianoGesang
      @PianoGesang 4 роки тому

      Yes, but what is done with the end result in the test tube?

    • @aldurocher
      @aldurocher 4 роки тому

      ​@@PianoGesang you can perform gel electrophoresis on it to visualize the results

    • @PianoGesang
      @PianoGesang 4 роки тому

      @@aldurocher Is that done by laser? I can look it up myself, thanks for the buzzword.

  • @Stepperfoot
    @Stepperfoot 8 років тому +1483

    That was so dramatic lol

  • @SozEmad
    @SozEmad 3 місяці тому +28

    the music background was so dramatic and it got happy ending 😂

  • @tednosaur6257
    @tednosaur6257 8 місяців тому +23

    Ah yes, intense war movie music to go with some intense hard working DNA polymerases

  • @Vinmob01
    @Vinmob01 9 років тому +116

    Love the eyes on the polymerase molecules - mischievous and full of intent!

  • @itszefflah5350
    @itszefflah5350 3 роки тому +79

    One hour lecture= Not understand about pcr
    3 minutes video with no voices= Understand everything about pcr

  • @RinkuSingh-ed3wi
    @RinkuSingh-ed3wi 11 місяців тому +12

    This is why animation is best way to explain things especially in biology
    Thanks a lot ❤❤❤

  • @Mirrori
    @Mirrori 4 роки тому +15

    Our teacher always showed this video at lab tech school when we talked about PCR. But she never keeped musics on.
    Now i probably understand why.
    But yeah i understand why did she show this because this is very helpful.
    And i never got my own PCR test to work correctly in school.
    Good memories.

  • @seppukuchuan5608
    @seppukuchuan5608 8 років тому +222

    Hands down the most dopest video I've viewed as far as learning more about the PCR specifically the taq polymerase :D Really helped. Thanks!!!

  • @user-jl3lp3kc3z
    @user-jl3lp3kc3z 3 роки тому +11

    this is the most epic pcr video ever made

  • @SynnoveJamila
    @SynnoveJamila 3 роки тому +18

    The music is epic. I'm studying for my exam, and I'm feeling as dramatic as this video right now.

  • @alexandriaalles7649
    @alexandriaalles7649 Рік тому +9

    The music with the animations cracked me up!! Thanks for making! Very helpful!

  • @Chanelifiable
    @Chanelifiable 7 років тому +143

    The drama. I started cracking up when the music kicked in.

    • @yeglabrat
      @yeglabrat 6 років тому +1

      I sang along at the beginning to Zarathustra, and cracked up at the part where it reaches PEAK EPICNESS. I'll be sending this to my instructor friends for their students.

  • @carolvitellas8497
    @carolvitellas8497 4 роки тому +3

    I watched this video back in 2017 while studying for my MCAT and I ALWAYS remembered it. Now I am back for some nostalgic review, 3 years later, as a second year medical student studying for STEP 1. Still as amazing as I remembered.

  • @mohangurunathan8634
    @mohangurunathan8634 3 роки тому +5

    This is one of the only videos which clearly explains the variable length DNA fragments that occur. Thank you so much.

  • @KristysEdits
    @KristysEdits 4 роки тому +25

    Best explanation ever

  • @studybiotic
    @studybiotic 2 роки тому +23

    well done and thx for this dramatic music

  • @rajifusama
    @rajifusama 8 років тому +572

    intro music too majestic i kenot

    • @OrnateOwl
      @OrnateOwl 8 років тому +2

      +rajifusama Pls, spoodermen!

    • @saurabhtripathi9590
      @saurabhtripathi9590 5 років тому

      that music was from movie 2001 a space odesye

  • @simphiwedhlamini5399
    @simphiwedhlamini5399 6 років тому +2

    Thanks to your video i secured about 15 marks in a 20 mark essay from my genetics exam yesterday. Thank you! :)

  • @isadorah4969
    @isadorah4969 4 місяці тому +12

    Why is this video keeping my serotonin high af

  • @Julia-ri8cu
    @Julia-ri8cu 3 роки тому +9

    This music and croissant-like polymerase made me smile before my exam, thanks! I love it

    • @0n1k6
      @0n1k6 3 роки тому

      Makes me hungry

  • @samrobbins4520
    @samrobbins4520 Рік тому +5

    I don't understand the need for this music, but good on you folks for trying to provide educational materials.

  • @hikingnorth9043
    @hikingnorth9043 3 роки тому +7

    BRUUH the music, I can't.
    You could make an epic trilogy with this soundtrack

  • @maxsteinberg7350
    @maxsteinberg7350 4 місяці тому +15

    this video >>>> the ~50 slides my prof gave us for pcr

  • @Hydro.Gaming
    @Hydro.Gaming 3 роки тому +22

    Damn I remember seeing this video in school, now came through this as a med student. Time flies!

    • @kamalreza.m4805
      @kamalreza.m4805 3 роки тому +1

      Goodluck bro

    • @elpidakeremidou3702
      @elpidakeremidou3702 3 роки тому

      true dat..

    • @Anupamchess
      @Anupamchess 4 місяці тому

      Bruh bro is going to become a doctor while having 26k subscribers on his Gaming channel...💀
      Mad respect bro

    • @Hydro.Gaming
      @Hydro.Gaming 3 місяці тому

      @@Anupamchess thx lol

  • @justpennie5068
    @justpennie5068 9 місяців тому +5

    this is amazing and pretty informative even without narration. I lowkey felt like i was watching a movie with all the dramatic and suspenseful music which added so much and kept me interested in the video. swell job!

  • @mahmoudsweda8012
    @mahmoudsweda8012 2 роки тому +12

    the music makes me feels I am having a dance with the PCR😂😂😂

  • @DeceptaconAgain
    @DeceptaconAgain 3 роки тому +10

    I liked the epic music, it actually made me more engaged.

  • @granthuttar5755
    @granthuttar5755 7 років тому +48

    Very easy to follow illustration of the PCR process. Educational and not overly complicated so many can learn from it.

  • @victoriavirador2699
    @victoriavirador2699 3 роки тому +3

    Después de presentar la PCR más de 10 veces durante la pandemia, me he encontrado este video. Lástima no haberlo encontrado antes, ¡genial!. Muchas gracias gentes del CSIC, que os vaya bien en vuestras carreras científicas.

  • @stamonicaswayzel7963
    @stamonicaswayzel7963 3 роки тому +6

    they made me understand this topic without actually saying a word. thankyou!

  • @bangtanseva2604
    @bangtanseva2604 3 роки тому +12

    This is so helpful u guys cannot imagine . It's been 7 years since u posted this . Its the pandemic and students are learning from youtube . Pcr is so important. Students type in the search bar and this video comes. What a save .... I would like to thank the team .

  • @linafessi67
    @linafessi67 2 роки тому +4

    I'm a french biology student and this is an amazing video. Every student should watch it

  • @Linkmon99
    @Linkmon99 4 роки тому +47

    THX I PASS BIO NOW

  • @tanyajain9950
    @tanyajain9950 5 місяців тому +13

    Concept is clear🎉❤
    But the background music was so dramatic😊
    It seems that it's the most daunting task existing 😅😅

  • @anjalikumarikashyap9141
    @anjalikumarikashyap9141 4 роки тому +68

    The background music scared the shit out of me at the beginning though

  • @waffles764
    @waffles764 Рік тому +5

    Ugh I’ve been stressing on what exactly is happening during a pcr. This helped so much thank you

  • @addicted6262
    @addicted6262 6 місяців тому +12

    Music make it feel like i am in a war or something 😂

    • @Pachjtene
      @Pachjtene 6 місяців тому +2

      Everytime i have to re-learn PCR:

  • @iiiiiiiii6579
    @iiiiiiiii6579 3 роки тому +17

    I laughed way too hard because of the music, thank you

  • @Racheal700
    @Racheal700 6 років тому +2

    This was awesome..not sure why people are complaining about the music. The point is what hes showing us and its a great informative video.

  • @jorgi0135
    @jorgi0135 Рік тому +11

    I died when the head on the bottom right popped up to the music

  • @mridulverma2516
    @mridulverma2516 2 роки тому +21

    The music is just......Like Something Akashvaani is goin to happen...👌😂😂

  • @proximacentauri2684
    @proximacentauri2684 5 років тому +23

    It's 6:43 in the morning. I spilled my coffee like something out of a sitcom lol the music scared the shit out of me. good video though

  • @charanSparsh7
    @charanSparsh7 Рік тому +8

    You don't know, How much you have helped Indian pre medical exam aspirants 😂

  • @meow5692
    @meow5692 Рік тому +5

    Back ground music almost got me heart attack but yup animation was just amazing , thank you everyone who were involved .

  • @Sameer_Malik18
    @Sameer_Malik18 2 дні тому +3

    10 years of making this video.. Still how amazing 😮😮

  • @BrigitteLP
    @BrigitteLP 4 роки тому +2

    Llevo 10 años trabajando como bióloga molecular y esto es de lo mejor que he vsto. Epiquísimo ¡Gracias!

  • @shazleenatasha
    @shazleenatasha 3 роки тому +10

    the background music is so epic until it leaves marks(memories) in my brain. thanks!!!

  • @CarterColeisInfamous
    @CarterColeisInfamous 9 років тому +20

    i love how epic it this is... really helps you feel the power and gravity of the reaction

  • @wealllive2
    @wealllive2 9 років тому +244

    That musics though....

    • @2201km
      @2201km 9 років тому +7

      +Ang Li epic music.

    • @amarug
      @amarug 7 років тому +3

      yes, 3:55 min of chronic ambivalence between "oh thanks for the useful info" and "wtf did you smoke while adding the music".

  • @kayo6689
    @kayo6689 8 місяців тому +4

    This makes the # of PCR copies so clear... no one told me that sometimes variable-length target sequence DNA is counted as a copy of the target sequence too!

  • @frapechinokelsey6451
    @frapechinokelsey6451 3 роки тому +6

    I'm in 12 standard from INDIA 🇮🇳 & I found this video which really boosted my knowledge ☺

  • @saibaba1106
    @saibaba1106 10 років тому +24

    It was seriously amazing....now I can easily understand and write my exam well!

  • @sciencesynergy-g4h
    @sciencesynergy-g4h Рік тому +6

    I even clapped for you🤗🤗...you made I felt the animation...whoever is behind this video should keep it up

  • @malinideori4966
    @malinideori4966 3 роки тому +2

    I have studied pcr from multiple books but today after watching your videos I learnt about pcr to the core..now I have no doubts.. n thank you so much for putting this up😃😃😃😃

  • @user-vm4om7dx3g
    @user-vm4om7dx3g 2 роки тому +5

    The animation is great. I'm a Korean school teacher, so you can use this video as a background for education.

  • @BhagwaniDevi-eb4uu
    @BhagwaniDevi-eb4uu 3 місяці тому +20

    Who is watching this video in 2024 ???

  • @danielg1680
    @danielg1680 3 роки тому +4

    I'm crying 😢 because this video really helped me a lot....
    Thanks

  • @planetyam6044
    @planetyam6044 5 років тому +10

    in my exam : " explain about the PCR technique".
    my head: _2001 music starts playing_

  • @elisenitouche2371
    @elisenitouche2371 6 місяців тому +13

    D-polymerase looks like it's judging me. I love it.

  • @Bookworm23184
    @Bookworm23184 Рік тому +6

    This is the most useful video i've ever watched

  • @tracy4259
    @tracy4259 2 роки тому +7

    Simple, clear, thorough. Thank you.

  • @jahnavee_palsodkar
    @jahnavee_palsodkar 4 роки тому +2

    This is just THE BEST video about PCR I've ever watched! The animations make it really easy and fun to understand it. Awesome job guys!

  • @andreainzaghi7373
    @andreainzaghi7373 3 роки тому +3

    the best short video I have seen. Even if it is short, it is very explicative. Number one!!

  • @rulamudhafar7930
    @rulamudhafar7930 5 років тому +3

    How simple and smart this explanation is !!
    How great your efforts are. Thanks ,many thanks !!

  • @viveksudhir2479
    @viveksudhir2479 3 роки тому +15

    Felt like i saved the entire galaxy at the end!! lol

  • @jessicakwiecinski
    @jessicakwiecinski 4 роки тому

    Why did I almost cry. Never been more impressed by a lesson on PCR

  • @Yousefmmohammed
    @Yousefmmohammed 4 роки тому +3

    Honestly that cool video is a real representation of what the word 'creativity ' really means .

  • @nihaljagtap4873
    @nihaljagtap4873 3 роки тому +10

    It's really helpful and kinda humorous too bcoz of music👌🏻

  • @ValentinaHGomes
    @ValentinaHGomes 8 місяців тому +5

    thank you so much!! the animation really helps to understand the whole process!! big thanks from brasil!

  • @DarthGangsta
    @DarthGangsta 4 роки тому +1

    My bio professor told me in a hw assignment to find a video explaining PCR and post a link in my response. I've found the ideal video.

  • @AlenaKazikova-mh2eq
    @AlenaKazikova-mh2eq Рік тому +35

    why so dramatic💀

  • @caro_alexandra
    @caro_alexandra 3 роки тому +4

    Cortito y al punto, excelente video!!
    Se entendió todo perfectamente, muchas gracias!

  • @user-ri8ps6cl4w
    @user-ri8ps6cl4w 3 роки тому +19

    great video, but the music choice is... interesting

    • @sakhti9962
      @sakhti9962 3 роки тому +2

      I muted it, felt it was way too distracting.

  • @weizhang6938
    @weizhang6938 Рік тому +3

    one of the best demonstrations I have ever seen on this subject!

  • @TemeraireBjartskula
    @TemeraireBjartskula 5 років тому +2

    This is simply incredible! Definitely one of the best (study) videos in existence... the animations make sense and the music totally finishes it

  • @pradyutdas7358
    @pradyutdas7358 Рік тому +15

    I came here to learn about PCR. But now I feel like I can kill a band of Orcs.

    • @hayaaldalq
      @hayaaldalq Рік тому +2

      I have q what is the fate of the primar in PCR?
      Does it become part of the amplified dna
      Or get removed at the end of PCR?

    • @JDogtheAutisticGiant
      @JDogtheAutisticGiant Рік тому

      @@hayaaldalq Primers are incorporated into the strands being synthesised as shown in the video. They become the beginning end (5' end) of the new strand.

  • @fatinnabilah2366
    @fatinnabilah2366 3 роки тому +10

    i dont know why i laugh but the background music sksksksksksk

  • @pierc1ngs
    @pierc1ngs Рік тому +18

    the music background😭

  • @sivasankarisiva2919
    @sivasankarisiva2919 3 роки тому +4

    Super animated explanation. A voice without speech

  • @bhavyaupadhyay794
    @bhavyaupadhyay794 6 місяців тому +6

    Such a intense music made me feel i can do anything after learning this

  • @sujathaprabhakar769
    @sujathaprabhakar769 5 років тому +4

    Best video about PCR. Thanks and big salute to the entire team

  • @ihanba
    @ihanba 5 років тому +1

    Why can't I like this video more than once? It's excellent!

  • @xzettxhabenx3389
    @xzettxhabenx3389 4 роки тому +9

    Nobody:
    Our instructors: assigns this video

  • @dicle743
    @dicle743 Рік тому +5

    The best animation video on PCR

  • @bernardohochman9100
    @bernardohochman9100 3 роки тому +3

    Este video es increible! Horas tratando de entender el tema, hasta ahora. GRACIAS!

  • @carlosalmeida8435
    @carlosalmeida8435 4 роки тому +2

    Thank you very much for this video, finally I understand why there is much more copies of the desired DNA region than the variable lenth DNA. GOD bless you!

  • @sidratwani8860
    @sidratwani8860 5 місяців тому +18

    This music sounds like the end of a superhero movie

  • @lindamarialal
    @lindamarialal 9 років тому +149

    That background music though! X'D

  • @user-uj8og9cm9d
    @user-uj8og9cm9d 3 роки тому +5

    Great video, in my head I was picturing the off target amplicons (the ones that are from original template and extend beyond the reverse primer) and I was picturing that you would get a amplicons of a variety of sizes over the thickness of a band of agarose. Which apparently is correct but is irrelevant as the target amplicons quickly dwarf the off target ones in number.

  • @jesseduran8244
    @jesseduran8244 4 роки тому +5

    Absolutely incredible. Simple and clear.

    • @sandeshdaluwatta5250
      @sandeshdaluwatta5250 3 роки тому

      Do you think this is the most accurate way to detect COVID 19?

  • @_LAA406
    @_LAA406 2 роки тому +3

    I have never seen any video more easily understandable than this...👍

  • @wajihazahoor2530
    @wajihazahoor2530 Рік тому +4

    The best video I've seen and the explanation through pictorial representation is so good

  • @salmaamoukal3036
    @salmaamoukal3036 2 роки тому +33

    i cant with the music I-

    • @Hasanjanac
      @Hasanjanac 2 роки тому

      mute your audio

    • @radioloop2311
      @radioloop2311 2 роки тому +2

      @@Hasanjanac i think they meant in an absurd or comical way which is agreeable

  • @marianaarroyo5835
    @marianaarroyo5835 Рік тому +6

    Great video! Absolutely loved the background music! Incredible!

  • @heathermill12
    @heathermill12 2 роки тому +15

    this was so emotional :'(

    • @adannanmezi3672
      @adannanmezi3672 2 роки тому

      literally said this to myself 1 second before reading your comment🤣

    • @theinnominatoidk3821
      @theinnominatoidk3821 2 роки тому

      yeah I love how dramatic it is lol