What are your thoughts on Phizer ordering sequences from SinoPeg and SinoBiological which utilized polyethylene glycol sequences which use graphene and using them in vaccines?
‘For us, therefore, we’re really taking that leap - us as company, Bayer, in cell and gene therapy, which to me is one of these examples where really we’re going to make a difference, hopefully, moving forward. Ultimately the mRNA vaccines are an example for that - cell and gene therapy - I always like to say that if we had surveyed two years ago in the public, “would you be willing to take a gene or cell therapy and inject it into your body” - we would have had probably a 95% refusal rate. I think this pandemic has also opened many people’s eyes to innovation in a way that was maybe not possible before.’ - Bayer Executive Stefan Oelrich, in a speech at the World Health Summit, October 2021.
Thank you for this video. I am trying to do the experiment on same but I got stuck with the calculation part. I most of the research papers the dilution part is missing. How much conc would I dilute the lipids and my nucleic acid part of the same concentration given in the video?
The system they use to insert the drugs inside of lipids…what is that system? Is it a big machine? Is it a robot? Do they just put the ingredients in a cup with a lid and shake it up? What’s the process of the combining of the lipids and the drugs?
it’s called a microfluidics device. they can be scaled for lab settings or for large manufacturing. I have personally worked with one in my previous lab to encapsulate mRNA inside LNPs.
@@ScientistSwanda how does it encapsulate the drug? Is there any kind of footage? Does it send electric impulses into the solution tuned to the frequency needed for them to just combine on their own? Or do they have small little nano robot arms that insert material into the lipids?
@@ScientistSwanda I just looked up a company who sells these kinds of devices…so I gather basically nobody knows how these machines actually work…because scientists just buy them and use them…the people to ask would be the ones who actually build these devices…
I appreciate that you're sharing your medical knowledge with us. It's always helpful to learn from experts.
my pleasure!
Thank you so much for this brief introduction of LNP, Dr Swanda! Tremendously helpful for a non-biology background person like me. Appreciate!😊
You're very welcome! I’m glad it is helpful ☺️
This video is a great reminder to stay vigilant about our health and to listen to our bodies.
What are your thoughts on Phizer ordering sequences from SinoPeg and SinoBiological which utilized polyethylene glycol sequences which use graphene and using them in vaccines?
Well done! I’d like to hear about more drugs that have successfully used this method. I think you’re a great teacher!
siRNA added to future topics! ✅
‘For us, therefore, we’re really taking that leap - us as company, Bayer, in cell and gene therapy, which to me is one of these examples where really we’re going to make a difference, hopefully, moving forward. Ultimately the mRNA vaccines are an example for that - cell and gene therapy - I always like to say that if we had surveyed two years ago in the public, “would you be willing to take a gene or cell therapy and inject it into your body” - we would have had probably a 95% refusal rate. I think this pandemic has also opened many people’s eyes to innovation in a way that was maybe not possible before.’ - Bayer Executive Stefan Oelrich, in a speech at the World Health Summit, October 2021.
This is such an important topic, especially for those who are at higher risk for blood clots. Thank you for spreading the word.
You are an excellent science communicator! I really appreciate your videos and clear explanations.
it’s my pleasure! science is for everyone!
Awesome ! i have been reading several publications but was not able to easy understand the LNP structure . Thank you for making science simple
It\'s amazing how complex our bodies are and how everything is connected. Thanks for breaking it down for us.
What do you think about LNP's from a drug being found in every organ throughout the body?
Top notch science educator! 🙌🏼 Thanks for explaining this!
thank you so much for your continued support, Karin! ♥️
Thank you for this video. I am trying to do the experiment on same but I got stuck with the calculation part. I most of the research papers the dilution part is missing. How much conc would I dilute the lipids and my nucleic acid part of the same concentration given in the video?
Thank you for being so informative and engaging in your videos. I always learn something new from you!
I'm so glad! Thank you for the support 😊
Thanks ! It will be really usefull for my presentation about mRNA vaccines ;)
How do you calculate N/P ratio molar ratio ? Can you please explain in detail ?
The system they use to insert the drugs inside of lipids…what is that system? Is it a big machine? Is it a robot? Do they just put the ingredients in a cup with a lid and shake it up? What’s the process of the combining of the lipids and the drugs?
it’s called a microfluidics device. they can be scaled for lab settings or for large manufacturing. I have personally worked with one in my previous lab to encapsulate mRNA inside LNPs.
@@ScientistSwanda how does it encapsulate the drug? Is there any kind of footage? Does it send electric impulses into the solution tuned to the frequency needed for them to just combine on their own? Or do they have small little nano robot arms that insert material into the lipids?
@@ScientistSwanda I just looked up a company who sells these kinds of devices…so I gather basically nobody knows how these machines actually work…because scientists just buy them and use them…the people to ask would be the ones who actually build these devices…
what you have gathered is incorrect. a simple pubmed search can tell you exactly how they work, good luck.
@@ScientistSwanda ok. I’ll check it out. Thanks. You’re the first person to ever answer this question for me! Appreciate it
Gone going
Nice video flag
So you let a Corporation program your cells 😮😮😮😮😮😮😮😮😮😮
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