How mRNA Vaccines Work - Simply Explained

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  • Опубліковано 3 тра 2024
  • mRNA vaccines have to potential to end the COVID19 pandemic. How do they work? Are they safe? And how could they've been developed so quickly?
    The main idea of mRNA vaccines is to trick our bodies to produce part of a virus. This kickstarts our immune response, without getting us sick. All that's needed is a part of the virus's DNA or RNA, packaged into mRNA. Cool!
    (mRNA is the technology behind the vaccines from Pfizer/BioNTech, Moderna & CureVac)
    💡 Follow-up video
    • mRNA Vaccines: Questio...
    I answer 10 of your mostly asked questions (and address some misconceptions).
    📚 Sources used to make this video:
    savjee.be/videos/simply-expla...
    ☝️ This page also contains answers for frequently asked questions.
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    #mrna #vaccine #covid19 #simplyexplained
  • Наука та технологія

КОМЕНТАРІ • 3,1 тис.

  • @scofah
    @scofah 2 роки тому +240

    I really appreciate how you didn't have any background music or sound effects in this video. I'm so tired of all the noise/racket in the background of videos.

    • @The_mountaingirl
      @The_mountaingirl 2 роки тому +1

      True💯💯

    • @wolfthorn1
      @wolfthorn1 Рік тому +2

      too true.
      Nothing worse than a two minute intro of dubstep at level ten.

    • @jeffreyperez2178
      @jeffreyperez2178 Рік тому +1

      Oh my gosh yes!

    • @michaelackerman8455
      @michaelackerman8455 Рік тому

      I cannot agree more. I find background 'music' so irritating and intrusive that I am unable to watch the video. This video was brilliant, thank you very much!

  • @syngen462
    @syngen462 2 роки тому +16

    Yes, and 2 vaccines and 100 boosters later!!

  • @walkerb392
    @walkerb392 2 роки тому +6

    But why we also hear people still experiencing symptoms and other illness after getting mRNA vaccines..??

  • @andrewhate5925
    @andrewhate5925 2 роки тому +7

    Why do we need second dose if our immune systems already know that thing

    • @MjoedDrikkar
      @MjoedDrikkar 2 роки тому +1

      B cells doesn't last forever, and if it is a reocurring experience your immune system will increase the amount of b cells in total in your body.

    • @goodvibes1525
      @goodvibes1525 2 роки тому +1

      Many vaccines have a second dose

  • @panamahub
    @panamahub 3 роки тому +1274

    so basically you don't need the whole enemy to train your soldiers only show them how the enemy's weapon look like.

    • @simplyexplained
      @simplyexplained  3 роки тому +113

      Haha yeah! Cool analogy!

    • @giovanigalagnara
      @giovanigalagnara 3 роки тому +9

      If your immune system will not react the spike you now produced more coronavirus. Can you have a presentation using DNA.

    • @Memphis2010GFC
      @Memphis2010GFC 3 роки тому +1

      Absolultely!

    • @Memphis2010GFC
      @Memphis2010GFC 3 роки тому +22

      We need to keep things in perspective. About 54 million covid vaccine doses have been given worldwide. We would all hope that no one experiences any side effects from the vaccine. I suggest the incidence of serious side effects is rare! It is very easy to highlight cases and blow things totally out of proportion. Which is greater: Getting a severe side effect or getting covid (which has known long-term side effects) and passing it on to others? What is your solution to getting out of the pandemic?

    • @fareli91
      @fareli91 3 роки тому +7

      More like showing a photo of their enemy rather than just their weapons, and rather than letting them figure out by themselves.

  • @Praestantia
    @Praestantia 2 роки тому +29

    I swear the thought process that went into these vaccines was clever as hell. Like, who thinks of using our own body to make the key markers of a virus which it will use to identify said virus? That's the most ingenious piece of biomedical engineering idea I've ever heard of.

    • @reveal102
      @reveal102 2 роки тому +8

      It is clever as hell. Some have likened it to the invention of the transistor.

    • @outdoorsrob3023
      @outdoorsrob3023 2 роки тому +9

      But with so many variations one will need booster after booster.

    • @SamuelBakutana
      @SamuelBakutana 2 роки тому +1

      Clever as HEAVEN. Hell isn't that clever.

    • @BazzaOTW
      @BazzaOTW 2 роки тому +2

      I believe the originator of the mRNA idea struggled to get funding or anyone interested, until of course until COVID came along…

    • @BazzaOTW
      @BazzaOTW 2 роки тому +3

      @@reveal102 Nobel Prize stuff for services to medicine and humanity in my opinion.

  • @carolejackson8357
    @carolejackson8357 Рік тому +7

    Good simple explanation but missing important parts like how does the body stop this loop of continuing to make the spike proteins. And what are the long term affects.

  • @john-cp8kx
    @john-cp8kx 2 роки тому +8

    The problem is that spikes circulate in the blood and the complex of spike and antibody may deposit itself on the cells of blood vessels causing an inflammatory reaction that damages the cells lining the blood vessels.

  • @Jurassiic
    @Jurassiic 2 роки тому +9

    At 3:05 it says you don’t get sick but many people have gotten sick with the injection , how come ?

    • @goodvibes1525
      @goodvibes1525 2 роки тому +1

      You don't get sick as in you don't get sick with covid

    • @Jurassiic
      @Jurassiic 2 роки тому +1

      @@goodvibes1525 but people with the vaccine have been getting sick with Covid and the different variants.

    • @Dish.Washer
      @Dish.Washer 2 роки тому +1

      The symptoms right after receiving the vaccine are common responses when your body wants to build immunity. Getting the vaccine doesn't make you invulnerable, just like wearing seatbelts doesn't mean you're not getting hurt if you crash

    • @HaloAubreeMariee
      @HaloAubreeMariee Місяць тому

      It's symptoms, but not full blown sickness (most times). Your body is producing active virus DNA, so when your cells replicate it, you might experience symptoms of the virus before your body can shut it down. And by the next day, you're usually a-okay again.

  • @Chipchase780
    @Chipchase780 3 роки тому +774

    This is the best and clearest explanation of mRNA vaccines I have heard so far. Excellent !

    • @simoneharvey-foote9134
      @simoneharvey-foote9134 3 роки тому +4

      seriously !

    • @temusombash4256
      @temusombash4256 3 роки тому +1

      Very good indeed!

    • @funkyfreak97
      @funkyfreak97 3 роки тому +17

      Better than my coworkers over a Skype call this morning. "mRNA will fuse to your genes and kill you." I'm still speechless. These people get paid around $25-40 an hour and they think Bill Gates is trying to microchip us. I only realized this morning how nutty a couple people on my team really are.

    • @DaniDani-zb4wd
      @DaniDani-zb4wd 3 роки тому

      @@funkyfreak97 Isn't 25-40$/hour quite a bit even for well developed countries? 25-40$/hour is a lot in my country where minimum net salary is 317 US dollars like imagine getting paid around1,5$/hour like not getting paid in a day of work as much as you get paid in one hour.

    • @rrajkamal
      @rrajkamal 3 роки тому +1

      I agree 100%!

  • @GQ-yb5kt
    @GQ-yb5kt 3 роки тому +40

    Great vid! Straight to the point, easy to digest, and quick. Literally everything i needed to know!

    • @conniemcmurray5146
      @conniemcmurray5146 2 роки тому +1

      I think it is misleading that the video didn't make clear that the vaxxx is meant to kill us all.

    • @the_modfied_car4903
      @the_modfied_car4903 2 роки тому +4

      @@conniemcmurray5146 go back to school

    • @CarlosVAsquez-kp2qf
      @CarlosVAsquez-kp2qf 3 місяці тому

      @@conniemcmurray5146 so where are all the millions of dead people?

  • @SreeOne
    @SreeOne 3 роки тому +68

    I gave thumbs up for the last part of your Video. Dont just trust me, deep dive into the sources. Nice .

    • @gailbenton8642
      @gailbenton8642 2 роки тому +5

      Sources: Forbes, Wiki, Business Insider, Twitter?

  • @Kelsie_Lista_Brinza
    @Kelsie_Lista_Brinza 3 роки тому +138

    My concern is by sending a message to your cells to replicate the "spike" and then to later attack that spike could be setting our bodies up for autoimmune disease.

    • @slooob23
      @slooob23 3 роки тому +103

      Which might not materialize for many months or even years later. I am not taking an experimental medication like this until it is proven safe.

    • @kenn3758
      @kenn3758 3 роки тому +52

      The mRNA that tells our cells to produce the spikes are very unstable. They are degraded very quickly and does not remain in your body long term. It is only temporarily there to teach your cells to recognize the enemy. It's like how you would teach maths to kids , but you're not going to stay with them the rest of their lives to show them how to multiply.

    • @slooob23
      @slooob23 3 роки тому +64

      @@kenn3758 all you are doing is describing the theoretical mode of action and the intention of the medication. What happens in real world situations is unclear at this stage, though people have already died after taking this experimental medication. Describing the intention is somewhat meaningless in this context.

    • @kenn3758
      @kenn3758 3 роки тому +43

      @@slooob23 I understand your point of view. Though I must highlight that this 'theoretical' mechanism has been well studied for decades, meanwhile the deaths (if any) from this category of vaccines are extremely rare. That is like saying you won't walk outside during the rain because lightning could hit you. Yes there may be a slight possibility of negative effects, but the expected benefit you and your community get from this vaccine heavily outweigh them.

    • @slooob23
      @slooob23 3 роки тому +42

      @@kenn3758 to my knowledge this is the first RNA vaccine ever produced, in that regard how can we have high confidence in it until a suitable period of time and the associated monitoring is complete? We also don't know how long it is effective for, corona viruses being notoriously difficult for lasting immune response. If the vaccine is only effective for a few months the risk profile becomes rather more of an issue.

  • @davidagiel8130
    @davidagiel8130 2 роки тому +15

    Spike proteins themselves can still cause lung damage and blood thickening.

    • @talltree3941
      @talltree3941 2 роки тому

      💩

    • @awayfarer6813
      @awayfarer6813 2 роки тому

      @@talltree3941 like, oh 💩 !!!?

    • @talltree3941
      @talltree3941 2 роки тому

      @@awayfarer6813 no, like this guy “David” is trying to push some bullshit story to try to scare people from getting the vaccine. So the emoji is meant to mean “bullshit”. But maybe I coud Try: 🐂💩

    • @awayfarer6813
      @awayfarer6813 2 роки тому +4

      @@talltree3941 Haha, well, I just hope people are doing their due diligence and homework about the vaccine before making a decision, and not stopping at this simple video. I respect whatever personal decision people make...and what I mean by personal is thinking for oneself, and not giving in to coercion or societal pressure either way you go.

    • @talltree3941
      @talltree3941 2 роки тому +2

      @@awayfarer6813 I got fully vaccinated in March. No issues. I live in a large city. Millions have gotten fully vaccinated. I haven’t heard of anyone experiencing any serious side effects.

  • @rikkisaxx684
    @rikkisaxx684 Рік тому +5

    Unfortunately studies are showing that the spike is toxic and also very damaging. So Mrna thought our bodies to produce damaging toxins in a large way therefore making our immune systems go into continuous overdrive eventually leading to self destruction causing immune failure.

    • @jimmyswaggart1189
      @jimmyswaggart1189 Рік тому

      So by your reasoning this would happen with the natural virus as well as the vaccine?

    • @JK_JK_JK
      @JK_JK_JK 11 місяців тому +1

      @@jimmyswaggart1189 What is the Covid-related mortality for non-elderly persons with no comorbidities??

    • @jimmyswaggart1189
      @jimmyswaggart1189 11 місяців тому

      @@JK_JK_JK Well that's a question that is impossible to answer now isn't it so why ask it?

    • @JK_JK_JK
      @JK_JK_JK 11 місяців тому +1

      @@jimmyswaggart1189 Try again after looking at the data.

    • @jimmyswaggart1189
      @jimmyswaggart1189 11 місяців тому

      @@JK_JK_JK Again this has been answered before and it's an impossible to answer.

  • @tumnaharring5233
    @tumnaharring5233 3 роки тому +8

    Thank you so much.. saved me from failing in my Final school year Bio Examinations
    ... Hoping to get at least 90... 7 questions from the subject came and I answered it will thanks to you

    • @MacLuckyPTP
      @MacLuckyPTP 2 роки тому +4

      You will not get 90 if you take vaccines frequently.

    • @stellarch9524
      @stellarch9524 2 роки тому +1

      @@MacLuckyPTP what?

    • @SHREDTILLDEAD
      @SHREDTILLDEAD 2 роки тому +1

      @@stellarch9524 you will not live to be 90

    • @stellarch9524
      @stellarch9524 2 роки тому +1

      @@SHREDTILLDEAD I like how you didn’t even correctly explain it, this guy is talking about grades not the age so your clearly just as stupid as the guy I replied to

  • @cindysagers9552
    @cindysagers9552 3 роки тому +6

    Wonderful! Thanks for the straightforward explanation. Brilliant!

  • @sophielowe1417
    @sophielowe1417 2 роки тому

    Thank you for taking the time to simply explain. First video that I have found that actually makes it clear and precise.

  • @PinkeySuavo
    @PinkeySuavo 2 роки тому +3

    1) So why more than 1 injection is needed?
    2) Why there are any side effects or people feel sick and so on?
    3) Why there's a talk about "long term side effects"? How learning the body to fight against virus can cause long term side effects?

    • @coleross1562
      @coleross1562 2 роки тому

      you can find these all with a simple google search

    • @PinkeySuavo
      @PinkeySuavo 2 роки тому

      @@coleross1562 but im too lazy

  • @lunamoon9935
    @lunamoon9935 3 роки тому +24

    One of the best explanation videos ever!!

  • @melanie8388
    @melanie8388 3 роки тому +10

    I've been trying to find a clear and simple video to show friends and family, this is perfect - thank you!

  • @MikesterCurtis
    @MikesterCurtis 2 роки тому +6

    The immune system is amazing. I think you could add to the video the effects someone might experience while the immune system tackles the intruder. But keeping it simple is a good way to teach, generally.

  • @Vearyn812
    @Vearyn812 2 роки тому +2

    wow, not mentioned any risks, only the benefits. Bravo

  • @maurakoulik982
    @maurakoulik982 3 роки тому +9

    Great explanation and graphics!

  • @mahavati3696
    @mahavati3696 3 роки тому +25

    Well that shattered one or two illusions I had! Thanks for that video.

    • @tdottees7146
      @tdottees7146 3 роки тому +8

      just like that huh? did you bother to research further? probably not...

    • @randyrandall8274
      @randyrandall8274 2 роки тому +1

      @@taraakins8273 Whaaaat? Wow, just....wow 🤦

  • @user-uy3eq5hg1s
    @user-uy3eq5hg1s 3 роки тому +76

    My concern is that this is the first time mRNA has been used on humans in such a wide scale before. The experts say it is safe, but how can we know for sure that there will not be long term side effects?

    • @jonny555333
      @jonny555333 3 роки тому +19

      Because we know exactly how it works. It's isn't just some random procedure. We have known how mrna works for decades and we simply are using that knowledge to teach out cells to fight off a virus.

    • @maxmorris4562
      @maxmorris4562 3 роки тому +43

      @@jonny555333 we don’t know the ramifications and the majority of us can fight off the virus with our immune system so we don’t all need it

    • @minpat7518
      @minpat7518 3 роки тому +43

      @@jonny555333 no, this has never been done before on humans and everyone gettin it are guinea pigs to fight a virus that’s 99.998% survivable!

    • @whyp9552
      @whyp9552 3 роки тому +23

      @@minpat7518 lol if you don't have a good resson to get vaccinated (like a disease or whatever) and you don't want to be vaccinated you're irresponsible and more or less an idiot

    • @caryfrancis8030
      @caryfrancis8030 3 роки тому +8

      @@maxmorris4562 we know how RNA works, my buddy began working on this more than 20 years ago.

  • @findyourpassion8722
    @findyourpassion8722 2 роки тому

    I love your ability to Simply Explain complex topics. Subscribed.

  • @jear4766
    @jear4766 3 роки тому +29

    You really make it easy to understand. Thank you so much!

  • @swayp5715
    @swayp5715 3 роки тому +16

    Thank you brother!

  • @A3Kr0n
    @A3Kr0n 2 роки тому +7

    Listing sources gets a huge thumbs up.

    • @JoshxIZ
      @JoshxIZ 2 роки тому +1

      You get a gold star if u get ur 2 injections :)

  • @haydenmacfarlane7194
    @haydenmacfarlane7194 3 роки тому +7

    Thanks for the explanation. Easy to understand and relatively quick/to the point.

  • @Urketadic
    @Urketadic Рік тому +5

    In theory it sounds great, in practice its unfortunately not.

  • @AstralPhnx
    @AstralPhnx 3 роки тому +18

    Incredible video explaining some incredible technology! I'm amazed by the scientists that managed to come up with this technique and put it into effective use! Incredible stuff!

    • @garryallison5679
      @garryallison5679 3 роки тому +13

      I wouldnt get to excited. Lets see how it works a year down the line.

    • @nickizcool20
      @nickizcool20 3 роки тому

      @@garryallison5679 it works great

    • @nickizcool20
      @nickizcool20 3 роки тому

      @@garryallison5679 I got the vaccine it’s awesome. I feel great

    • @3chords490
      @3chords490 3 роки тому +1

      @@nickizcool20 the placebo effect....

    • @AC-lh3qb
      @AC-lh3qb 3 роки тому +5

      why are people dying from the vaccine?

  • @janecridland5105
    @janecridland5105 3 роки тому +23

    Perfect amount of information, explained concisely. Thank you!

  • @timstimbre9762
    @timstimbre9762 2 роки тому +19

    Awesome, couldn't find any info on the actual breakdown of the produced spikes by the body's immune system after vaccination has taken place. This was clear and concise for laymen like me. :-)

  • @Christophers_Crafts
    @Christophers_Crafts 2 роки тому +4

    Then why are people getting so sick after the second dose?

  • @BrandonTorres
    @BrandonTorres 3 роки тому +17

    Really good explanation and super understandable, thank you!

    • @screeneducation4167
      @screeneducation4167 Рік тому

      Except he didn't mention the following:
      1. The purpose of the research Dr. Fauci funded was to engineer the spike protein to be EXTREMELY toxic. So the spike protein our bodies manufacture are just as toxic as the spike protein on the virus, and they are causing major problems.
      2. It's the spike protein that is mutating to create the new variants, which is why these vaxes don't provide lasting immunity ---- after the spike protein mutates, our immune system no longer recognizes the spike virus. Which is why dead antigen vaccines are so superior --- because we develop immune recognition to all 32 viral proteins, so when the spike protein mutates we can still recognize the rest of the virus.

  • @skiki222
    @skiki222 3 роки тому +3

    Thanks for sharing! Finally some clarity : )

  • @bencorley8687
    @bencorley8687 2 роки тому

    Thank you for making this so easy to understand. It really does help give me peace of mind.

  • @xxsexhaverxxreal1180
    @xxsexhaverxxreal1180 2 роки тому +4

    You can tell if someone is really smart they can explain complex things simply with ease.

    • @sweetbeat7
      @sweetbeat7 3 місяці тому +1

      asking the body to build lots of spike proteins? teaches us how to fight them off? may make sense to some but not to me.

    • @camokoy
      @camokoy 2 місяці тому

      The really smart people never took the jab in the first place

  • @thomask2616
    @thomask2616 3 роки тому +50

    Thank you, most articles act like I am a child when I read them.

    • @simplyexplained
      @simplyexplained  3 роки тому +2

      Glad you liked it!

    • @fidyculous
      @fidyculous 2 роки тому +7

      That might be because most of the people are behaving like children during this whole pandemic

  • @asymmetricfuzion970
    @asymmetricfuzion970 2 роки тому +8

    Dude. Thank you. I’ve recently got the new kurzgesagt book on immunology. It’s great but I either haven’t got to the MRNa but yet or it’s not covered. But I keep hearing about it and I keep hearing about “MRNa entering the cells nucleus” which sounded like bullshit. This totally clears up what the MRNa does so thank you 🙏

  • @dwcscca
    @dwcscca 3 роки тому +16

    This was great! Thanks for putting together such a logical and simple presentation.

  • @djl9154
    @djl9154 Рік тому +8

    Nice explanation and appreciated. The part about not getting sick is not quite accurate though. Maybe that is supposed to work that way, but typically doesn’t from all that I talked with, at least a few days. One study even indicating that the spike protein may be getting in the blood in a few cases, anything can take place if that happens. Guess will find out over time.

  • @garydean777
    @garydean777 3 роки тому +11

    If it is that simple then why are there so many people suffering severe side effects & why are so very many reputable & highly qualified doctors warning us not to take it? I don't get it.

    • @theotherorange3586
      @theotherorange3586 3 роки тому +2

      I don't think I like the sound of this. What happens when it mutates in your body? Your infecting yourself with something that might cause autoimmune disorder by the looks of it. I will take my chances with nature

    • @garydean777
      @garydean777 2 роки тому

      @@theotherorange3586 A lot of doctors have said precisely that.

  • @StefTechSurfer
    @StefTechSurfer 2 роки тому +5

    Now Govts need to market this with a brief explanation of how the vaccines work and endorsements.

    • @MrStruggle0
      @MrStruggle0 2 роки тому +1

      Exactly, they’re currently just advertising that you should get it and that everyone’s getting it, instead of actually explaining it so people can see it’s safe without having to take the governments word for it

    • @kasiawilk39
      @kasiawilk39 2 роки тому

      Nie,nie

  • @preetcharan
    @preetcharan 3 роки тому +18

    The easy going explanation so far.

  • @SmallFry01
    @SmallFry01 2 роки тому +8

    Amazing, super clear explanation. Well done!

  • @elizabeththomas6707
    @elizabeththomas6707 3 роки тому +3

    Very Well, and clearly explained, Great job👍

  • @onurguzel16
    @onurguzel16 3 роки тому +5

    Can you make a video for inactive vaccines (eg: for Covid 19) comparing to mRNA vaccines by versus? Appreciate. Great job.

  • @geraldinemyers7769
    @geraldinemyers7769 3 роки тому +151

    Amazing and totally clear, understandable explanation of covid vaccines. No highly technical mumbo jumbo that most researchers like to try and impress you with. A real breath of fresh air for anyone who wants to know what is happening inside them when they get that shot.

    • @norawhite1503
      @norawhite1503 2 роки тому +1

      That's me right now. Just got the second shot so I am wondering what happens to see if I am going to feel bad or not.
      Amazing video

    • @JohnDouqh
      @JohnDouqh 2 роки тому +2

      Forgot to mention ade

    • @H.K-tm
      @H.K-tm 2 роки тому

      Very true. Same here

    • @telemarketer1584
      @telemarketer1584 2 роки тому +3

      ikr? I watched one and they were like "fancy science words... blah blah" and I didn't understand a thing. This one makes sense! I think it's really important that people explain things in normal terms, so ordinary people can understand it too. Don't try to impress us with technical terms, impress us with a clear, understandable explanation

    • @JohnDouqh
      @JohnDouqh 2 роки тому +7

      @@telemarketer1584 for a better explanation on how these “vaccines” work. Just go to John Hopkins COVID tracker. Pick your favorite heavily vaccinated country (Israel, Canada, Australia, Gibraltar) look at the timeline of COVID cases and deaths. Notice how the majority occur AFTER the “vaccine” rollout . I’ll let you figure out what that means.

  • @JoannaLaurensings
    @JoannaLaurensings 2 роки тому +2

    So if you can’t get sick, why are some people getting symptoms after taking it?

  • @jordankeats8327
    @jordankeats8327 3 роки тому +16

    Short and sweet, wonderful and informative video!

  • @elizabethquintal2499
    @elizabethquintal2499 2 роки тому +54

    Excellent video. So simple, easy to understand, informative and educational. Thank you! In fact, this video should be sent to the CDC so they can better inform the public instead of confusing them.👍👏

    • @MegaTrivial
      @MegaTrivial 2 роки тому +8

      Maybe their intention and point, is to confuse

    • @mommyshark5106
      @mommyshark5106 2 роки тому +1

      @@MegaTrivial yeah they want fear, not facts.

    • @MegaTrivial
      @MegaTrivial 2 роки тому

      @@mommyshark5106
      - it sucks.. I wish authorities were starting to behave normal, no need of power over us LoL 😆😆🙂🔌🔌🔌🔌

  • @shadowman7408
    @shadowman7408 2 роки тому +2

    Still doesn't explain what happens to the cells that manufactured the mrna.

  • @reneecowan3194
    @reneecowan3194 3 роки тому +1

    Great explanation and easy to understand. Everyone should watch this.

  • @maxinemacdonald35
    @maxinemacdonald35 3 роки тому +3

    Really helpful and easy to understand. You've greatly put my mind at rest! Thank you so much for taking the time to put this video together!

  • @courtneyc.647
    @courtneyc.647 3 роки тому +14

    So helpful! Thank you so much for this video.

    • @deliciosatv8401
      @deliciosatv8401 3 роки тому

      Yes, I agree with you. cool video! clear and easy to understand!

  • @vivekchandraundirwade7059
    @vivekchandraundirwade7059 2 роки тому

    Awesome explanation. Keep up the good work Champ!!

  • @manon8600
    @manon8600 2 роки тому +3

    if mRNA vaccines can't make us sick, how come a lot of people experience covid symptoms (fever, fatigue, etc) a for a few days after vaccination? (not being edgy, just asking sincerely)

  • @mackenmd
    @mackenmd 3 роки тому +75

    You have done the world a public service by creating this video and I will share this to all corners of my little world and hopefully it'll spread. Thank you also for providing references in the description. Well done!

    • @simplyexplained
      @simplyexplained  3 роки тому +3

      Thanks for your kind words! Really means a lot. I hope other people will also see the value (and the trolls stay away)

    • @mackenmd
      @mackenmd 3 роки тому +3

      @@simplyexplained You are very welcome. Ignore all the trolls and anybody else that doesn't have a constructive question or comment. I know, easier said than done. In particular, there is one person I will target this video to: she is a fitness/motivational influencer on UA-cam and has urged her followers to avoid vaccines at any cost. I will be sending her your video link directly. Her chief complaint is the mRNA component of the vaccine. This is especially why I'm appreciative of the references in the description. Keep up the fantastic work!

    • @martyes9563
      @martyes9563 3 роки тому +2

      Spread...like a virus!? (Sorry, little vaccine joke)

    • @mackenmd
      @mackenmd 3 роки тому +1

      @@martyes9563 we need laughs so no need to be sorry ;-)

    • @chanfranc
      @chanfranc 3 роки тому +5

      Hope this video will calm down the anti-vaccine people.

  • @MiladFarjadian
    @MiladFarjadian 3 роки тому +4

    Thanks! Easy and understandable.

  • @user-nf1hm3ny6s
    @user-nf1hm3ny6s 2 роки тому

    This is such a great explanation! Thank you so much!

    • @JoshxIZ
      @JoshxIZ 2 роки тому

      This is great:) now u too can get this amazing injection from god.

  • @izamils
    @izamils 2 роки тому

    Thank you so much! This really helps me with my Life Sciences 11 Project!

  • @TheMicahwitz
    @TheMicahwitz 2 роки тому +6

    Talk about the side effects now.

  • @Apochocolate
    @Apochocolate 3 роки тому +40

    This is the first time in my life I'm learning how vaccines work. Thank you for making this knowledge so accessible!

    • @pungency101
      @pungency101 3 роки тому +15

      This isn't how vaccines work though. This is an experimental technology 😂 learn some basic science please

    • @wickedwonderland9831
      @wickedwonderland9831 3 роки тому +8

      @@pungency101 The video starts with the basic principles. What are you on about?

    • @Apochocolate
      @Apochocolate 3 роки тому +1

      @@surfinmuso37 Would be interested in seeing the research you're looking at that puts these numbers in context.

    • @Apochocolate
      @Apochocolate 3 роки тому

      @@pungency101 You're so smart dude

    • @pungency101
      @pungency101 3 роки тому +7

      @@Apochocolate I've been studying medicinal chemistry for over 5 years... I'm well enough informed to know this is an experiment

  • @ManufactureBelief
    @ManufactureBelief 3 роки тому +2

    Please explain how it is impossible for the synthetic mRNA to enter the cell nucleus. I've not seen any explanations on why this is impossible anywhere. They just say it's impossible. As a commercial risk analyst my role requires me to list all the possible risks (even unlikely ones) for any large purchases/contract agreements that need approving by the exec. This is so they can make an informed decision. No one is giving any detailed listing of the risks, including 1, 2, 3 - 5, 10 year and longer term horizons. What are the potential risks, however unlikely, if its even remotely possible, they should be listed so we can make an informed decision. If execs expect such for a mere $1 million purchase, what makes this any different?

  • @dongilpark2701
    @dongilpark2701 2 роки тому

    Nice animation. I rarely looked at this quality video.

  • @xxkq0
    @xxkq0 2 роки тому +32

    I had the 2nd dose of Moderna recently and had pretty bad flu symptoms for about 24 hours (headache especially when moving quickly, muscle pains, fever, skin sensitivity, fatigue etc.). This video says there are few side effects because there is no live virus but side effects are pretty common at least for Moderna and Pfizer, so what is the mechanism that causes this? Immune system overreacting to the spike proteins?

    • @Banishedsoulsofficial
      @Banishedsoulsofficial 2 роки тому +7

      MRNA is a retrovirus. When a virus Is replicating it needs certain conditions. A fever means it is doing what it does to replicate. It's not a vaccine by definition it is infact gene therapy using a man-made retrovirus as a delivery system. You really shouldn't do the boosters, you shouldn't have done the covid shot at all. But that is your choice and you made it

    • @adama9032
      @adama9032 2 роки тому

      To much misinfo thanks for clearing it up

    • @thesmiffable
      @thesmiffable 2 роки тому +7

      @@Banishedsoulsofficial You are suffering from what's called the Dunning Kruger effect... you think you understand the whole picture but really, you're clueless.

    • @thesmiffable
      @thesmiffable 2 роки тому +2

      When
      someone can't type mRNA properly, it's a dead giveaway of where they are coming from.

    • @cwdgamedev1017
      @cwdgamedev1017 2 роки тому +6

      @@Chad_Max I recently watched a talk given by a biochemist who worked at Pfizer for 10 years. He said that there no attenuation (that he was aware of) of the vaccine's effect, which is to cause cells (which cells?) to produce the spike protein. Once you're injected, your body will be producing those spike proteins indefinitely. And since they're so small, they are able to penetrate the blood brain barrier. This leads to clotting (strokes) and inflammation elsewhere in the body. Your body will constantly be fighting to eliminate them and it likely won't be able to catch them all. They're going to build up and we're going to see what the long term effects of that are. It's probably not going to be pretty.

  • @tgy119
    @tgy119 3 роки тому +8

    In North America, why is the government not procuring traditional vaccines from Russia or China. If I had a choice, I’d much prefer the traditional weakened or dead virus vaccine over mRNA version.

    • @Subfightr
      @Subfightr 3 роки тому +2

      I HAD the same feeling as you. For me, an mRNA engineered vaccine was new, I didn't understand it, thus I was afraid of it. But when I took the time to watch several hours of videos from the engineers themselves, it was fully explained, the theory behind it, the amazing mechanism used to create it, my fears were lifted. Let us not go back to sleeping under the covers because we are afraid of the monster in the closet, I feel it we were to shine a light on it, we would see our fears are unfounded. I appreciate that you have watched this video at the very least.

    • @pushandr_
      @pushandr_ 3 роки тому +1

      Well if you google how Russian, most of Chinese and also Astrazeneca/Cambridge vaccines are made you will realize they are not traditional at al :) They all use an adenoviral vectors to achieve basicially the same what the mRNA vaccines are doing in this video, but with some extra steps (DNA to mRNA transcription) . This vaccines are basically give you an infection with genetically engineered adenovirus (usually in nature this virus is responsible for the common cold), that unable to replicate because of deletion of many important genes in it, they just use this virus to deliver genetic information to the cells of your body, so they can produce some sars-cov-2 spike proteins and trigger the immune system. Still not sure which technology is better though, they all have pros and cons.

    • @mahasimha8379
      @mahasimha8379 3 роки тому

      Sputnik V, traditional no side effect vaccine..

    • @pushandr_
      @pushandr_ 3 роки тому

      ​@@mahasimha8379No, adenovirus based vaccines are quite new, it is completely different technology compared to your seasonal flu shot for example, please use google...

  • @yako668
    @yako668 2 роки тому +1

    If developing vaccines takes about 8 years to get approved, how comes that the CoronaVac vaccine or Sinopharm which were developed using the traditional method, got approved for emergency use in less than a year?

  • @theorialogos
    @theorialogos 2 роки тому +3

    Very good explanation, thank you.
    Many people I know who get vaccinated get sick almost immediately with covid type symptoms. Why is that?

  • @glw5166
    @glw5166 3 роки тому +12

    What an excellent and informative video! Thanks!

  • @shadowofzeus6267
    @shadowofzeus6267 3 роки тому +4

    a very nice simple explanation - thanks so much!

  • @progress-ms3du
    @progress-ms3du 2 роки тому +2

    Very graphically & clearly illustrated - quick questions tho :
    1. What is the synthetic mRNA (syn-mRNA) made from?
    2. How & (more importantly) why does the body destroy the syn-mRNA?
    3. How long after it's introduction is syn-mRNA removed. ?
    4. Does this affect efficacy timelines ( hence booster shots ) ?
    5. Does this removal of the synthetic mRNA from the cell have any destructive effect on the cell itself, either in the ribosome or the nucleus or indeed the whole cell?
    6. For how long do the B-cells retain the infectant 'information ' ?

    • @stefc7122
      @stefc7122 2 роки тому +1

      Good questions.
      He also used the words DNA and RNA as if they were the same thing and I’m not sure why.
      I think the 2 places he does this need further clarification.

  • @ripkirby3498
    @ripkirby3498 2 роки тому +3

    The most beautiful explanation in its simplicity. Great video !!

  • @bluesky5384
    @bluesky5384 3 роки тому +3

    Thankful for this video and the (majority) of comments being informed and intelligent for once.

  • @KingsleyOseiAbrah
    @KingsleyOseiAbrah 3 роки тому +6

    You really made this very easy to understand! Thank you!

  • @billylim5268
    @billylim5268 3 роки тому

    Very good video - simple and clear explanation!

  • @elizabethhurtado2829
    @elizabethhurtado2829 Рік тому +2

    What if a person already has a hyperactive immune response and how long dies this stay in your body and what is the connection to heart and kidney disease?

  • @revelations4396
    @revelations4396 3 роки тому +21

    I like your explanation. However, it must be cautioned that this technology does not have a track record. What will happen when this synthetic rna is produced in other parts of the body? In the case of covid, what about the lipid enclosed nano particles? They are basically tricking the cells into making a synthetic compound. What is being used to create this synthetic compound? What happens to the synthetic compound that was used to create this protein? Can the nano particles be remotely manipulated? How is it possible for the vaccine to enter the cells?

    • @PD-yd3fr
      @PD-yd3fr 3 роки тому +7

      @@renitapayno Jerusalem Times had an article about these mRNA vaccines. I am not an antivaxer I know vaccines work, but this is an entirely new type of vaccine, never been approved for use in humans before. I don't know why they would not used the tried and true weakened/dead virus for a vaccine

    • @revelations4396
      @revelations4396 3 роки тому +8

      @@renitapayno , do you mind sharing that article? I have too many questions about the platforms that they are using with this vaccine. I personally find the whole process very troubling. No one is talking about the nanotechnology used in this vaccine.

    • @3274BigBlueBotics
      @3274BigBlueBotics Рік тому

      Tried to warn coworkers against using this new technology that, ultimately, injects itself into your cells and manipulates them to produce spike proteins instead of what it normally produces.
      Extremely invasive.
      Most importantly, I said it's not worth taking a risk given you are young and healthy and are at no risk.
      Of course, they called me anti-vaxxer.

  • @manu23325
    @manu23325 2 роки тому +3

    Nice explanation, but I still don’t understand how the immune system understands that those produced spikes have to be killed, as they don’t cause any harm.

  • @dan4091
    @dan4091 3 роки тому +9

    Good, now we know how it is **supposed** to work, but what are the possible downsides to teaching the body how to make spike proteins.

  • @tonymak9213
    @tonymak9213 2 роки тому +4

    So that's the theory. But what about all the spike proteins travelling around the body and causing mayhem in vital organs?

  • @alanoliver9956
    @alanoliver9956 3 роки тому +4

    The vaccine is mRNA. mRNA is genetic code. The vaccine is genetic code. He forgot to mention that.

  • @morris5439
    @morris5439 3 роки тому +9

    I wanna to know what kind of body cells will take up those mRNA? Are those cells being specifically selected or randomly absorbed? Once those body cells start marking the viral protein and display on their surface, will the T-cell treat them as foreign and attack those cell also? Just like rejection in transplantation?

    • @azaraliyev2064
      @azaraliyev2064 3 роки тому +2

      Good question and it is about 4 days no answer)

    • @morris5439
      @morris5439 3 роки тому +6

      @@azaraliyev2064 Either no one can give the exact answer, or someone know the answer but not wanna disclose it.

    • @bemusedbandersnatch2069
      @bemusedbandersnatch2069 3 роки тому

      I've been wondering about that too. I would assume they're just thrown out of the cell to hang out in the tissues or work their way over to the bloodstream where immune cells can find them. (Cells absorb and release proteins all the time after all.)

  • @roimordechay2975
    @roimordechay2975 2 роки тому +4

    Great! And also, once I hear someone says: "But don't take my word for it! All sources [...] are listed below", then you got me. Hit the subscribe button :)

  • @my_opiniondemocracy6584
    @my_opiniondemocracy6584 2 роки тому +1

    superb....hats off to those people who thought the idea of making a blue print of that portion in the virus that produces the spikes... excellent

  • @ibh9999
    @ibh9999 2 роки тому +3

    Towards the end, the video man says "don't take my words".

  • @jamieatkinson1581
    @jamieatkinson1581 3 роки тому +17

    I really needed this... it has been so hard to comprehend this new type of vaccine and I finally get it. I could even explain it to others if I had to

    • @conniemcmurray5146
      @conniemcmurray5146 2 роки тому +8

      Make sure to explain that it is the spike protein that kills people and that this is a depopulation shot.

    • @hyperbot2328
      @hyperbot2328 2 роки тому +3

      @@conniemcmurray5146 i got it and didnt die. And where did u get that information?

    • @Nowhereoh
      @Nowhereoh 2 роки тому +1

      @@conniemcmurray5146 Prof. Bhakdi puts it down, Dr Robert Malone mRNA vax tech inventor thinks all the data is fake. There are are at least ten to many more natural and 2 cheap generic solutions that make jab EUA invalid.

    • @Nowhereoh
      @Nowhereoh 2 роки тому +2

      @@hyperbot2328 Retired German prof. Bhakdi argues against, not depop argument. Vax tech inventor Dr. Robert Malone who had vax for travel thinks all the data is fake. Why am I talking to a bot?

    • @cribbycrabby7321
      @cribbycrabby7321 2 роки тому

      @@Nowhereoh why are you crazy talking?

  • @DardaniaLion
    @DardaniaLion 2 роки тому

    You got my subscription. Totally clear explanation.

  • @joeingy8777
    @joeingy8777 2 роки тому

    Awesome video, straight to the point and very comprehensible.

  • @shamariridley4890
    @shamariridley4890 2 роки тому +2

    How does the MRNA vaccine work against new variants because isn't the RNA of the variant different? If the RNA sequence of the vaccine is based on the original COVID virus? Great video and should definitely be shown to people who are hesitant towards the vaccine.

    • @Mohankeneh
      @Mohankeneh 2 роки тому

      youre right. the spike protein is different, but it is similar. with each mutation, the current vaccine which was created for the OG strain, will get most likely less effective. it still shows to have some efficacy so definitely better than nothing.

  • @elenaortega5459
    @elenaortega5459 Рік тому +5

    Very nice and clear. Now explain what happens in real life. I dare you.

  • @gsc1ugs
    @gsc1ugs 2 роки тому

    Explained really well for the mere mortal such as I

  • @Auraya1986
    @Auraya1986 2 роки тому +2

    As a virus a Spike Protein is used to dock on the cell, what happens with all the spike proteins that are now generated by the own body? Do they also dock on a cell or they just floating around in the blood?

    • @sadismx2137
      @sadismx2137 2 роки тому

      They are supposed to get destroyed. That's the whole point of the vaccine, to train your body to recognize and destroy the spike proteins.

    • @Auraya1986
      @Auraya1986 2 роки тому

      @@sadismx2137 the body is constantly producing the spike protein and destroying it? It sounds like war

    • @sadismx2137
      @sadismx2137 2 роки тому

      @@Auraya1986 I'm not sure if its constantly producing it, as the mRNA containing those instructions is also destroyed along with the spike proteins.

  • @heff4heather
    @heff4heather 2 роки тому +5

    Wait, so what happens if your immune system starts attacking your own cells because they now contain the mRNA of the spikes in their own cells?

    • @TravisJeScott
      @TravisJeScott 2 роки тому +2

      THEN you have a pandemic

    • @bluewaveafrica1092
      @bluewaveafrica1092 2 роки тому +1

      Lol

    • @heff4heather
      @heff4heather 2 роки тому

      Or is this not how it works, I don't know lol; is the mRNA lost during mitosis or apoptosis??

  • @AdamNZ
    @AdamNZ 2 роки тому +6

    I had the worst reaction from my second phizer vaccine and so did my partner.

    • @Mr.Monta77
      @Mr.Monta77 10 місяців тому

      You don’t know why that happend. It could be something else that caused your reaction. Don’t make the assumption that because two phenomena occour simultaniously, that one is caused by the other. That is a logical fallacy. It could be the vaccine but to claim it is a mono-causal and often erroneous explanation.

  • @jtveg
    @jtveg 2 роки тому +1

    Thanks so much for sharing. 😎👌🏼

  • @krishnabala8403
    @krishnabala8403 2 місяці тому

    Thank you! Clear and short explanation.