Reverse Transcriptase: an Enzyme that copies RNA to DNA

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  • Опубліковано 4 жов 2024
  • www.explorebio...
    This video describes the Nobel Prize winning discovery by David Baltimore and Howard Temin of reverse transcriptase, an enzyme that copies RNA into DNA. Retroviruses, which have a genome made of RNA, use reverse transcriptase to replicate. This discovery came as surprise because the widely accepted Central Dogma postulated only a one-way flow of information from DNA to RNA to protein. Reverse transcriptase later played a major role in biotechnology industry, providing a mechanism for cloning DNA from cellular RNA and making cDNA libraries. Learn more reverse transcriptase and viruses in Mike Bishop's Narrative on Cancer Genetics in The Explorer’s Guide to Biology (explorebiology.org/summary/genetics/the-genetic-basic-of-cancer).

КОМЕНТАРІ • 43

  • @TheExplorersGuidetoBiology
    @TheExplorersGuidetoBiology  Рік тому +1

    We present biology as detective work and focus on the process of science. Find out more at explorebiology.org

  • @alexgehrke8231
    @alexgehrke8231 4 роки тому +37

    I just learnt more in this 4 minute video than I did in a 12 week long university class

    • @Thefunksoulbro
      @Thefunksoulbro 3 роки тому +2

      Perhaps you could explain to me what I have just watched please. I've not got it?

    • @dealerataris
      @dealerataris Рік тому

      Years ago I stumbled onto a 3D animated “inside the cell” video that showcased a lot of what my professor was covering in my honors college biology II course, but seeing it come to life made things far clearer... same idea of condensing the course down into a few minutes. The prof loved showing videos like this in class so I figured I’d share it with him.. Pretty sure he got offended because he HATED my guts after that. Oops! 😀

  • @jaxnaturals
    @jaxnaturals 2 роки тому +5

    So a new studies shows that the pf izer and mod erna v a x does reverse transcriptase

  • @taladiv3415
    @taladiv3415 3 роки тому +2

    Never take anything for granted!

  • @zerobambiro
    @zerobambiro 3 роки тому +9

    Is this important for the corona vaccine?

    • @Megan-sl4mc
      @Megan-sl4mc 3 роки тому

      no

    • @DeeDee-qz6cg
      @DeeDee-qz6cg 3 роки тому +2

      It could be relevant.

    • @arenkai
      @arenkai 3 роки тому +2

      @@Alias9000 Being exposed to the virus itself puts you at risk of having its RNA being integrated to your genome, which is already happening in fact. And it's not as dramatic as it sounds, since all it does is make you positive to covid-19 even though you have 0 viral charge.
      Given how RNA is a very short lived molecule that gets degraded in less than 24 hours, the possibility for it to affect anything months or years down the line would be quite spectacular.
      Those chances are also always lower than the possibility of exposure to Sars-cov-2 having the same effect since it's DNA-based, and DNA is more stable than RNA.
      (Remember, Sars-cov-2 replicates in your body for up to 2 weeks before symptoms appear)
      So, in conclusion: even by taking into account the possibility of RNA being integrated to human genome, the vaccine is still safer than the virus itself

    • @ProfFeinman
      @ProfFeinman 3 роки тому

      Covid is not a retrovirus.

    • @salemdesigns65
      @salemdesigns65 2 роки тому +1

      @@ProfFeinman
      Truely, we don't know what Covid is.
      IF there is a 'Covid'.

  • @b-music9329
    @b-music9329 3 роки тому +2

    Extremely interesting! Very well done video!

    • @clashinghub3971
      @clashinghub3971 2 роки тому

      Can you say me what she said at 1:52 which enzyme

  • @jasonuren3479
    @jasonuren3479 2 роки тому +2

    Amazing that this was discovered in 1975, yet I've heard so many over the last couple of years saying it'd be impossible 🤔

  • @magznificent7845
    @magznificent7845 4 роки тому +2

    Thank you so much

  • @pavadaiarumugam9723
    @pavadaiarumugam9723 3 роки тому

    Thank you so much. This is what im searching for

  • @laraibafzal5585
    @laraibafzal5585 Рік тому +1

    Reverse transcriptase of hiv is used for the conversion of RNA into viral /host DNA?? PLEASE ANSWER

    • @dominicyelin
      @dominicyelin Рік тому

      HIV modifies the hosts dna. That's why people with aids have a damaged immune system. Because their dna has been modified.

  • @yoontaerij
    @yoontaerij Рік тому

    fantastic ,thank you so much.. ;)

  • @lilgamerx2777
    @lilgamerx2777 2 роки тому

    Very well explained!

  • @thanhtatttoewin
    @thanhtatttoewin 4 роки тому

    Thank you

  • @jasperm.8093
    @jasperm.8093 4 роки тому

    Thanks

  • @rthmjohn
    @rthmjohn 3 роки тому

    Great video!

  • @clashinghub3971
    @clashinghub3971 2 роки тому

    What did the scientist isolated enzyeme pls reply

  • @Mr4thetruth
    @Mr4thetruth 4 роки тому +4

    Why the awful background cacophony?

  • @nickdagreat33
    @nickdagreat33 Рік тому

    Basically a PS6 can reverse engineer the backward capability of a PS5 but PS5 has to upgrade first. 🤣🤣🤣

  • @jeepz669
    @jeepz669 3 роки тому +1

    How the hell did I get here bruh

  • @gulsuozturk2853
    @gulsuozturk2853 4 роки тому +2

    ADAMSIN

  • @ExistenceUniversity
    @ExistenceUniversity 2 роки тому +1

    Dogma doesn't mean fact lol

  • @diegoabarcaramos5196
    @diegoabarcaramos5196 4 роки тому +1

    ta fachera

  • @ramasalah2890
    @ramasalah2890 2 роки тому

    مين فايت ع الفيديو من الشاملة 😂😂😂

  • @Priceygames
    @Priceygames Рік тому +1

    Is it the mark of the beast, just kidding