Summary of the video. Alzheimer's often starts in middle age. Up to 90% of cases can be prevented by lifestyle. Genes are not decisive. In Alzheimer's, toxic protein accumulations occur. This starts 20 to 30 years before symptoms appear. Dementia starts with mild cognitive impairment where intervention can still be effective. Four processes play a role: 1. inflammation 2. oxidation 3. lipid dysregulation 4. glucose dysregulation. People with (pre-)diabetes may already experience a lower cognitive state in middle age. Well-controlled diabetes does not have to lead to dementia. High LDL values, even at a young age, increase the risk of dementia. Five factors reduce the risk: nutrition, physical exercise, stress reduction, sleep and cognitive stimulation. The Mediterranean diet is recommended. Strength training, especially of the legs, can reduce the risk of progression from mild cognitive impairment to dementia by more than 35%. Bad stress increases levels of cortisol and adrenaline that are harmful to the hippocampus, which is responsible for memory and problem solving. Good stress, such as challenging activities, stimulates dopamine and promotes brain growth. During deep sleep, a cleaning process takes place in the brain. Reduced deep sleep can disrupt this cleaning process. Optimally, 7-8 hours of deep sleep are needed. Cognitive reserve protects against brain damage. Passive activities, such as watching TV, lead to cognitive decline. Complex activities are better. Brains continue to develop throughout life and remain plastic.
@@aureliapompili310 sleep has three very important components-regularity, quantity, quality (quality can be measured by sub-components-deep, REM, restlessness, stress, duration). Most people forget the regularity of bedtime and awakenings.
The marvellous thing I have observed after listening to many, many podcasts and reading books from a variety of experts is the consistency of the messages. If we eat a good diet, stay hydrated, sleep enough, do regular exercise, avoid toxins (like smoking, alcohol and drugs) manage our stress and keep our brains active and challenged, it's good for gut health, cardio vascular health, organ health, and brain health. The same good lifestyle elements promote every aspect of health 😊
The Drs. Sherzai are fantastic science communicators. So many things to think about but I have a few small things to tweak immediately. Thank you for another great Zoe podcast and for the entire series of bringing leading edge scientists to us.
Thanks for telling me it starts in your 40's I was diagnosed with bowel cancer on my 40th birthday and my relationship died due to zero support from my partner. Couldn't stay their no more as she happy to argue and fight in front of our son.. my dad got diagnosed with dementia 5 years before he passed away with sepsis he also had bowel cancer. My mum was very controlling. Stress sure is a silent killer...😢 For the record I will be 50 this year..
As an avid researcher for the last 15 years because of an illness, I would LOVE to see a neurologist and a cardiologist discuss the whole LDL research because what is being delivered from one to another is opposite ends of the spectrum. Some say higher LDL is needed because your brain needs fat and HDL and tryclercides are more important and then some doctors/researchers say low LDL under 70 is most important and don't worry about HDL. We need long term studies on a healthy population with higher and lower LDL.
My mother had dementia, my father early onset dementia, short term memory loss, but fortunately still has mental capacity even after turning 100 last year. This does as Jonathan says, leaves one in fear of what the future holds. Reducing the risk is welcome.
So great! What a dynamic, interesting, inspiring pair - I was leaning in the entire episode as there was so much actionable material here! Thanks for sharing them with us and hope to see them again.
Drink silicon rich water and read labels to avoid aluminum. MIND diet. Exercise. Source Dr. C. Exley. almost 40 years of research on AL. Also my friend's recovery. Good luck.
. . . so, so glad to see my 2 most respected & loved "Brain Doctors" . . . I have missed seeing them on YT...I Learn so much new info each time I get to see them.... God Bless each of them, and, you, also, for this wonderful interview.... 🙏🙏🙏
I read ,listened to previous Zoe podcasts. I think that the hippocampus, the cell in the brain that I think is the only one,that can regenerate slightly. Your Gut is the driver of your body. The food chain is vast, but as well as this and keeping active,exercises, physical etc. Stress unfortunately is not good. But positive mindsets your body and mind work as a team . I am learning lots from their pod casts 😊. Fantastic podcast..x
I had a lot of announcements from UA-cam while seeing this podcast. This is the first time this happens. I have seen all zoe's podcasts and thought they had no announcements.
I really enjoyed this extremely informative and interesting video from Dr Dean Sherzai and Dr Ayesha Sherzai courtesy of ZOE. Most of us are aware of or have been touched by Alzheimers in some way, shape or form. Please take on board what is being said and make adjustments in your own lifestyle to reduce your own risk factors. Many thanks for the content.
What a helpful and encouraging episode - and from such lovely people Drs. Aisha and Dean are (And Dean’s such an affirming husband, gently praising his wife’s achievements! ) Thank you all for this public health education podcast.
My grandmother had the "optimal lifestyle": no major stess, Mediterranean lifestyle with plenty of home-grown and wild organic food, long walks/skiing and social dances with new goreographies... still got dementia. My mother and her sister had similar lifestyle, except when my mother had stress when doing the accounts for the company she worked for, and the sister would watched a lot of TV after her mobility declined. They both had dementia (my mother had high blood pressure all her life). So, I expect to get dementia despite being on relatively healthy diet and still constanly learning something new: I have high LDL cholesterol despite being on vegetarian diet (mostly home cooked), exercising is highly restricted because anything I do gives me migraine and the quality of my sleep is poor so I wake up tired even if I sleep 7-9 hours, and my gut biome was healthy when it got tested.
It's hard but remember you tend to fulfill your expectations. So try to follow the good advice in the podcast and stop worrying as much as poss. All the best!
One factor that needs a closer examination is Glycemic lymphatic flushing. However there are studies to show how beneficial yoga is specifically for that. I practice everything noted, but I get the biggest buzz from yoga. I’m sure the main reason is that I spend the majority of the class with my head below my heart in a number of different poses. I can tell you for a fact that I’m crystal clear a short while afterwards. I swear it’s down to glymph-phatic system. Studies are definitely being worked on & id love to hear more about the benefits of yoga, in old age. So not just to keep the body supple. There are many different ways that yoga is beneficial for us. By the way I’m 72 and an AI Digital Marketer.
When LDL is discussed in your podcasts, you talk about LDL as a result of a poor diet. I eat a very good vegan diet, minimal UPFs, but my LDL is high because I have familial high cholesterol. The statins I took years ago had no impact on the level of LDL. I've recently begun taking Rosuvastatin because I'm told these have had good results for people like me. I'm yet to get my initial 3 monthly results. Does the fact that I have a very good diet and familial high LDL make any difference to my chances of getting Alzheimer's?
Great news for cyclists then - leg exercise and navigation (without a GPS) on new territory. I always think that when I'm riding, figuring out where I am, what road it connects to, planning the mostly circular ride in my head to get back home with the exact mileage I want - is a bit like London Taxi drivers. It's certainly great brain taxing planning/problem solving.
Riding a bike is mostly cardio-vascular and to a lesser extend muscle building, but you can enhance it by riding on a hilly terrain. I miss cycling buy unfortunately it is too dangerous where I live and the traffic is such it's just start-stop-start-stop... 😢
I would love Zoe to have a session or comment on the book "Change your diet change your mind" by Dr Georgia Ede, which seems to contradict everything that Zoe encourages of what a healthy diet should look like. I'm very sceptical reading, but it would be great to have an opinion on what their suggested ketogenic diets do to the gut and their long-term effects.
Unfortunately, if the message doesn’t endorse Zoe model, they will not promote it, whatever the evidence base. Similarly the cholesterol message. Bear in mind that the business minds behind Zoe intend this podcast to be an advertising vehicle. Nothing wrong with that, but the “science” needs to be viewed through that lens.
Really interesting and informative, but I do wonder, given the various stages of sleep, how we can manage 7-8 hours of deep sleep. Or how we can even guarantee a deep sleep?
So much helpful information. Thank you ! I heard the mention of reducing ldl. Do you recommend cholesterol medicines to aid that. I am so struggling not wanting to take it as my levels were not high and thought brain needs good cholesterol. Thanks again
Same question! I eat zero dietary cholesterol and am fully plant based but my LDL (and Apo an and B) are high. Nothing seems to move the needle. Hate the idea of statins but may have to consider.
Our bodies need cholesterol so bad, the liver and brain makes it daily! Low levels is the cause of brain fog, that's from my own n1 experience! There are numerous studies over the last twenty years that show this, but they are suppressed and I'm certain this comment will be also!
Well, the cholesterol scare & the over prescription of statins are controversial subjects. I suggest you research the role of cholesterol and the side effects of statins to learn more about them. One of the side effects is memory issues, and there are other undesirable changes in the body in long term statin users. With due respect to the presenters, I never heard it before that higher cholesterol can contribute to dementia. Unless they refer to triglycerides, which indeed is a health risk for the cardio vascular system. Yes, our bodies need cholesterol for many vital biological functions, such as new cell building, immune system function, hormone production and optimum nervous system function. Which no Dr will tell us is that there is a qualitative lipid panel test that can identify what type of LDL particles we have. The small, boyant LDL is healthy, but the larger, more sticky LDL is a concern. The curreny used blood tests don't look at this. I suggest listening to podcasts from highly esteemed researchers such as Dr. Robert Lastig (endocrinologist), Dr. Ben Bikman (biochemist) Dr. Ovadia (cardioligis, Dr. David Pearlmutter (neuroligist), and in the UK, Dr. Aseem Malhotra (cardiologist). ...and the list of cutting edge reserchers goes on. I sincerely hope that in 10 years' time, the healthcare systems will have a more modern and more current science based approach to blood lipid management.
@@zsofiazoltan7359 Yes. Zoe are demonising cholesterol, saturated fat and red meat yet again.......There are many respected scientists who think very differently on these subjects and have the research to prove it. Most agree on exercise, sleep, stress and eating real food but as to what kind of real food, that is where the disagreements lie.
@@zsofiazoltan7359thanks for posting this. I know Sarah Berry refers to these views as cholesterol deniers, but people need to be made aware that the Zoe line of messaging is not the only one.
Even children today have signs of artery disease. Fast foods and sugary drinks have long term consequences. There is an obesity epidemic today where over 60% of the population is overweight or obese. What is common today and "NORMAL" is not healthy. The average person today is not healthy and is taking medications. Heart attacks were once only common in people over 65. Today people in their 40 are having heart attacks. Add more plants and vegetables to your diet and less junk and overly processed foods Get off the couch. Get off the iphone or ipad. Get up and go for a walk, run, bike ride , garden, work outside. Move more, sit less. Daily exercise is key to as healthy life. Ride a bicycle to school, work or for fun. Riding a bicycle is a great way to exercise. Ebikes are bringing many older adults back to cycling. Cities need to do more to encourage people to ride bicycles. Safe protected bike lanes and trails are needed so adults and children can ride safely. Speak up for bicycles in your community. Bicycles make life and cities better. Ask your local transportation planner and elected officials to support more protected bike lanes and trails. Children should be riding a bicycle to school and not be driven in a minivan. Be healthier and happier. Ride a bicycle regularly. Make a bicycle your transportation option for short distance travel.
Well both my parents got dementia, father vascular, mother Alzheimer's. On my fathers side there was no dementia (both grandparents didn't get it). Not certain about my mother's because both her parents died young. In terms of NEURO and the O, my mother remained very active mentally until her mid 80's working in charities and was a stickler for crossword puzzles and Sudoku. She did them religiously. Both parents did a lot of exercise through walking and lots of physically demanding gardening. Both parents didn't drink heavily and neither ever smoked. The only one on your list that they might have been guilty of was consuming too much sugar, with both eating chocolate - and that being dark, which some reckon is a good form of chocolate. So clearly something else caused their dementia. It's these other factors I think which hold more of a clue to what is really going on. I did some water sampling at their house but it came back supposedly within a normal range. I think there are yet unknown reasons for the causes of dementia beyond just the NEURO formula described in this video.
A question for the excellent Doctors, if they are still able to comment. Would golf, taken seriously, which is a mental as well as a physical challenge combined, qualify as an excellent hedge against Dementia? I might argue that the social aspects of the game can also reduce stress. I can't find any studies of this online.
Ive read there are studies from Dr Richard Davidson's research that meditation can improve brain health and even grow some brain regions. Do you feel this is true?
In terms of reducing stress, certainly, and it may also stimulate the production of certain hormones, but I wouldn't dare to claim it as any affect on growth.
55:50 "...7 to 8 hours of it, of deep sleep..." What exactly is the definition of "deep"? According to my Fitbit sleep tracker, on a good night I get one hour of deep sleep, which according to them, this is about average for my age (73). I hope that's not as bad as it sounds...
Question: flax and chia seeds tend to go though the body undigested so how good source of omega are they really? How about cold pressed hemp oil, or hulled hemp seeds don't they have high omega 3 content with higher bioavailability?
I have been resisting taking statins recommended by my gp as my cholesterol is high despite a good diet. After watching this video, I’m beginning to think I should be taking them because of my LDL levels. What do others think?
Perhaps measure ApoB which is a more relevant overall metric and includes effects from LDL-C. Check out Simon Hill's interviews with the geeks of cholesterol and CVD. Good luck.
Up to you but I would do my own research. Read what Dr Malcolm Kendrick has to say on the matter. He and Zoe Harcombe (no relation to this Zoe) just won their legal case against the Daily Mail who had accused them of being statin deniers and being responsible for people dying as a result of stopping taking them. They were totally vindicated.
I had a babysitter, a nurse, who was physically very active and lean, but even vegetarian diet and benecol dis not lower her very high cholesterol. Only when she went on a vegan diet her cholesterol levels started dropping! I'm not saying it works for everyone but if you are worried about statins you might be motivated enough to try it. Be aware of processed foods such as meat alternatives and ready-made meals though. These days it's all too easy to be vegetarian l/vegan and still have unhealthy diet. Notice also that meat alternatives mostly do not have equivalent amounts of protein. For example, a vegeburger may only have a quarter of the amount of protein than a hamburger or none at all!
Oh goodness. For those of you not in the States, this is a Seventh Day Adventist couple from Loma Linda California that push a Vegan diet and STILL try to demonize saturated fatty acids for brain health for religious reasons (the opposite of what actual metabolic doctors like Dr. Georgia Ede and Chris Palmer are researching). They push a very high carbohydrate diet, even though the most up to date research is showing that Alzheimer’s is a disease of hyperinsulinemia and glucose intolerance. It's being referred to as type 3 diabetes for a reason. In their own words: "Meat and dairy contain high levels of saturated fat which raises blood pressure which isn't just bad for the heart but clogs up the brain too." They literally still follow the disproven 'belief' that saturated fat, which is metablized into efficient ketone bodies that can cross the blood brain barrier without insulin, somehow 'clogs' our hearts and brains. Ketones do not 'clog' anything. Be careful or there 🫡.
Thank you for that clarification. I was thinking that the negative emphasis they put on saturated fats and dairy clashed with my experience, knowledge and understanding of a ketogenic or low carb diet. It was at this point in the podcast that i started to feel uncomfortable regarding their dietary messages.
@@Caladcholg You do you! I’ll do me. I believe in eating a mostly plant based diet. Zoe has plenty of guests on their program that recommend this style of eating.
The Interview about seed oils by Sarah Berry on Diary of a CEO was disappointing. There was a lack of candid openness regarding potential conflict of interest. Please don't let that happen again as it could undo some of the good work you have done to date. Trusting the Messenger is of vital importance.
It was a car crash. I imagine the Zoe image managers are furious as they couldn’t control the message. Well worth a listen though to hear her call people “cholesterol deniers” as well as laugh at the idea that ultra processed seeds oils might not be a healthy foodstuff.
Why do these videos have to be so long? We all know why. You could shorten the video content and we could receive the same output. - It's a shame because the overall message is good but you lose a lot of viewers
I have read many books, I listened to many UA-cam videos by many of the world's leading gurus and health experts but nothing came close to the hidden herbs by anette ray. I recommend everyone giving it a read.
I pray to God that everyone who is reading this gets better and stays healthy. What helped me is using the herbs from the book the hidden herbs by anette ray
Summary of the video. Alzheimer's often starts in middle age. Up to 90% of cases can be prevented by lifestyle. Genes are not decisive. In Alzheimer's, toxic protein accumulations occur. This starts 20 to 30 years before symptoms appear. Dementia starts with mild cognitive impairment where intervention can still be effective. Four processes play a role: 1. inflammation 2. oxidation 3. lipid dysregulation 4. glucose dysregulation. People with (pre-)diabetes may already experience a lower cognitive state in middle age. Well-controlled diabetes does not have to lead to dementia. High LDL values, even at a young age, increase the risk of dementia. Five factors reduce the risk: nutrition, physical exercise, stress reduction, sleep and cognitive stimulation. The Mediterranean diet is recommended. Strength training, especially of the legs, can reduce the risk of progression from mild cognitive impairment to dementia by more than 35%. Bad stress increases levels of cortisol and adrenaline that are harmful to the hippocampus, which is responsible for memory and problem solving. Good stress, such as challenging activities, stimulates dopamine and promotes brain growth. During deep sleep, a cleaning process takes place in the brain. Reduced deep sleep can disrupt this cleaning process. Optimally, 7-8 hours of deep sleep are needed. Cognitive reserve protects against brain damage. Passive activities, such as watching TV, lead to cognitive decline. Complex activities are better. Brains continue to develop throughout life and remain plastic.
Thanks that’s incredibly helpful. Saved me twenty mins!
Thank you very much. Most helpful!
Thank you x
7-8 hours deep sleep?? Per night?? Or 7-8 hours sleep overnight.
@@aureliapompili310 sleep has three very important components-regularity, quantity, quality (quality can be measured by sub-components-deep, REM, restlessness, stress, duration). Most people forget the regularity of bedtime and awakenings.
The marvellous thing I have observed after listening to many, many podcasts and reading books from a variety of experts is the consistency of the messages. If we eat a good diet, stay hydrated, sleep enough, do regular exercise, avoid toxins (like smoking, alcohol and drugs) manage our stress and keep our brains active and challenged, it's good for gut health, cardio vascular health, organ health, and brain health. The same good lifestyle elements promote every aspect of health 😊
The Drs. Sherzai are fantastic science communicators. So many things to think about but I have a few small things to tweak immediately. Thank you for another great Zoe podcast and for the entire series of bringing leading edge scientists to us.
Thanks for telling me it starts in your 40's I was diagnosed with bowel cancer on my 40th birthday and my relationship died due to zero support from my partner. Couldn't stay their no more as she happy to argue and fight in front of our son.. my dad got diagnosed with dementia 5 years before he passed away with sepsis he also had bowel cancer. My mum was very controlling. Stress sure is a silent killer...😢 For the record I will be 50 this year..
"The Proof is in the Plants" pg 152. The section on colorectal cancer should be helpful. Fibre!
As an avid researcher for the last 15 years because of an illness, I would LOVE to see a neurologist and a cardiologist discuss the whole LDL research because what is being delivered from one to another is opposite ends of the spectrum. Some say higher LDL is needed because your brain needs fat and HDL and tryclercides are more important and then some doctors/researchers say low LDL under 70 is most important and don't worry about HDL. We need long term studies on a healthy population with higher and lower LDL.
My mother had dementia, my father early onset dementia, short term memory loss, but fortunately still has mental capacity even after turning 100 last year. This does as Jonathan says, leaves one in fear of what the future holds. Reducing the risk is welcome.
Read "Imagine You Are An Aluminum Atom"
Don't worry , you won't remember any of it and worrying makes it worse
So great! What a dynamic, interesting, inspiring pair - I was leaning in the entire episode as there was so much actionable material here! Thanks for sharing them with us and hope to see them again.
*My father's siblings, 4 out of 5, had Alzheimeirs. I am quite worried. I am 52. Thank you, great video!* 🌷
Drink silicon rich water and read labels to avoid aluminum. MIND diet. Exercise. Source Dr. C. Exley. almost 40 years of research on AL. Also my friend's recovery. Good luck.
. . . so, so glad to see my 2 most respected & loved "Brain Doctors" . . . I have missed seeing them on YT...I Learn so much new info each time I get to see them.... God Bless each of them, and, you, also, for this wonderful interview.... 🙏🙏🙏
Great interview. Thank you for allowing the guests to speak. Perfect timing of questions without interrupting them.
Super & world-class expert guests …. Amazing interview & wide-ranging information about the brain. Thanks to all three of you - it’s appreciated. 👏
I want to say a huge thanks to you guys for trying to help us listeners to become and stay healthy so we can live our best lives!!!
Magnificent presentation of Neuroscience Q & A episode. Thank you so much Jonathan and Doctors!!!
A fantastic episode! Thank you so much to the three of you
I read ,listened to previous Zoe podcasts. I think that the hippocampus, the cell in the brain that I think is the only one,that can regenerate slightly.
Your Gut is the driver of your body.
The food chain is vast, but as well as this and keeping active,exercises, physical etc. Stress unfortunately is not good.
But positive mindsets your body and mind work as a team .
I am learning lots from their pod casts 😊.
Fantastic podcast..x
I had a lot of announcements from UA-cam while seeing this podcast. This is the first time this happens. I have seen all zoe's podcasts and thought they had no announcements.
I really enjoyed this extremely informative and interesting video from Dr Dean Sherzai and Dr Ayesha Sherzai courtesy of ZOE. Most of us are aware of or have been touched by Alzheimers in some way, shape or form. Please take on board what is being said and make adjustments in your own lifestyle to reduce your own risk factors. Many thanks for the content.
What a helpful and encouraging episode - and from such lovely people Drs. Aisha and Dean are (And Dean’s such an affirming husband, gently praising his wife’s achievements! ) Thank you all for this public health education podcast.
A prime example of missing-information.
Nutrition
Exercise
Unwind/Stress
Restorative Sleep
Optimization of Cognitive Ability
I love how practical and science-backed these habits are.
My grandmother had the "optimal lifestyle": no major stess, Mediterranean lifestyle with plenty of home-grown and wild organic food, long walks/skiing and social dances with new goreographies... still got dementia. My mother and her sister had similar lifestyle, except when my mother had stress when doing the accounts for the company she worked for, and the sister would watched a lot of TV after her mobility declined. They both had dementia (my mother had high blood pressure all her life).
So, I expect to get dementia despite being on relatively healthy diet and still constanly learning something new: I have high LDL cholesterol despite being on vegetarian diet (mostly home cooked), exercising is highly restricted because anything I do gives me migraine and the quality of my sleep is poor so I wake up tired even if I sleep 7-9 hours, and my gut biome was healthy when it got tested.
Meditation, Qigong ,,,,may bring you benefits that youre missing in sleep etc..
It's hard but remember you tend to fulfill your expectations. So try to follow the good advice in the podcast and stop worrying as much as poss. All the best!
Excellent points about good and bad 'stress'. The problem can be sometimes be differentiating between the two in your personal life....
One of the best podcasts
Always great to see Dean and Ayesha
Wow!!!! So informative and food for thought. Thankyou so much
One factor that needs a closer examination is Glycemic lymphatic flushing. However there are studies to show how beneficial yoga is specifically for that. I practice everything noted, but I get the biggest buzz from yoga. I’m sure the main reason is that I spend the majority of the class with my head below my heart in a number of different poses. I can tell you for a fact that I’m crystal clear a short while afterwards. I swear it’s down to glymph-phatic system. Studies are definitely being worked on & id love to hear more about the benefits of yoga, in old age. So not just to keep the body supple. There are many different ways that yoga is beneficial for us. By the way I’m 72 and an AI Digital Marketer.
Thank you!
Fantastic and highly informative discussion with so many actionable lifestyle options. Thank you!
Thank you for a very interesting program. Greetings from a follower from Finland.
Excellent video! Thank you for posting! :)
Absolutely brilliant and life changing information
Excellent podcast.
Oh wow ! such good info .Thanks!
When LDL is discussed in your podcasts, you talk about LDL as a result of a poor diet. I eat a very good vegan diet, minimal UPFs, but my LDL is high because I have familial high cholesterol. The statins I took years ago had no impact on the level of LDL. I've recently begun taking Rosuvastatin because I'm told these have had good results for people like me. I'm yet to get my initial 3 monthly results. Does the fact that I have a very good diet and familial high LDL make any difference to my chances of getting Alzheimer's?
Absolutely helpful and informative podcast, thank you. Fascinating and what's more gives immediately actionable points NEURO ❤
Great news for cyclists then - leg exercise and navigation (without a GPS) on new territory. I always think that when I'm riding, figuring out where I am, what road it connects to, planning the mostly circular ride in my head to get back home with the exact mileage I want - is a bit like London Taxi drivers. It's certainly great brain taxing planning/problem solving.
Riding a bike is mostly cardio-vascular and to a lesser extend muscle building, but you can enhance it by riding on a hilly terrain. I miss cycling buy unfortunately it is too dangerous where I live and the traffic is such it's just start-stop-start-stop... 😢
@@oakstrong1 Thanks for your comment. I live in a very hilly area. I sometimes think I must look like a Kangaroo - thin arms and big legs - Ha!
Fascinating video, thank you Zoe !
I would love Zoe to have a session or comment on the book "Change your diet change your mind" by Dr Georgia Ede, which seems to contradict everything that Zoe encourages of what a healthy diet should look like. I'm very sceptical reading, but it would be great to have an opinion on what their suggested ketogenic diets do to the gut and their long-term effects.
Unfortunately, if the message doesn’t endorse Zoe model, they will not promote it, whatever the evidence base.
Similarly the cholesterol message.
Bear in mind that the business minds behind Zoe intend this podcast to be an advertising vehicle. Nothing wrong with that, but the “science” needs to be viewed through that lens.
Great chat. Very interesting AND helpful. Easy steps to follow. Thank you for sharing 🙂
Both my mum and her mother had dementia. I'm 60 years now and have suffered from chronic insomnia for the last 5 years. I'm doomed!
Have a blast while you can.
@@maryosborne8417 😉👍
I found this very helpful. Thanks.
Another brilliant podcast, so informative and so much invaluable advice. But please Johnathan, sit on your hands when you are interviewing.
Everybody on tv and youtube waves their hands about. It's really irritating!
Really interesting and informative, but I do wonder, given the various stages of sleep, how we can manage 7-8 hours of deep sleep. Or how we can even guarantee a deep sleep?
Excellent
It’s crazy no one here is talking about the hidden herbs by Anette Ray…
So much helpful information. Thank you ! I heard the mention of reducing ldl. Do you recommend cholesterol medicines to aid that. I am so struggling not wanting to take it as my levels were not high and thought brain needs good cholesterol. Thanks again
Same question! I eat zero dietary cholesterol and am fully plant based but my LDL (and Apo an and B) are high. Nothing seems to move the needle. Hate the idea of statins but may have to consider.
Our bodies need cholesterol so bad, the liver and brain makes it daily! Low levels is the cause of brain fog, that's from my own n1 experience! There are numerous studies over the last twenty years that show this, but they are suppressed and I'm certain this comment will be also!
Well, the cholesterol scare & the over prescription of statins are controversial subjects.
I suggest you research the role of cholesterol and the side effects of statins to learn more about them.
One of the side effects is memory issues, and there are other undesirable changes in the body in long term statin users.
With due respect to the presenters, I never heard it before that higher cholesterol can contribute to dementia.
Unless they refer to triglycerides, which indeed is a health risk for the cardio vascular system.
Yes, our bodies need cholesterol for many vital biological functions, such as new cell building, immune system function, hormone production and optimum nervous system function.
Which no Dr will tell us is that there is a qualitative lipid panel test that can identify what type of LDL particles we have. The small, boyant LDL is healthy, but the larger, more sticky LDL is a concern. The curreny used blood tests don't look at this.
I suggest listening to podcasts from highly esteemed researchers such as Dr. Robert Lastig (endocrinologist), Dr. Ben Bikman (biochemist)
Dr. Ovadia (cardioligis, Dr. David Pearlmutter (neuroligist), and in the UK, Dr. Aseem Malhotra (cardiologist).
...and the list of cutting edge reserchers goes on.
I sincerely hope that in 10 years' time, the healthcare systems will have a more modern and more current science based approach to blood lipid management.
@@zsofiazoltan7359 Yes. Zoe are demonising cholesterol, saturated fat and red meat yet again.......There are many respected scientists who think very differently on these subjects and have the research to prove it. Most agree on exercise, sleep, stress and eating real food but as to what kind of real food, that is where the disagreements lie.
@@zsofiazoltan7359thanks for posting this. I know Sarah Berry refers to these views as cholesterol deniers, but people need to be made aware that the Zoe line of messaging is not the only one.
Hating the ads!
Agreed. Real pity but I think zoe is struggling financially unfortunately
Amazing stuff
Two fabulous guests
Even children today have signs of artery disease. Fast foods and sugary drinks have long term consequences.
There is an obesity epidemic today where over 60% of the population is overweight or obese.
What is common today and "NORMAL" is not healthy. The average person today is not healthy and is taking medications.
Heart attacks were once only common in people over 65. Today people in their 40 are having heart attacks.
Add more plants and vegetables to your diet and less junk and overly processed foods
Get off the couch. Get off the iphone or ipad. Get up and go for a walk, run, bike ride , garden, work outside. Move more, sit less.
Daily exercise is key to as healthy life. Ride a bicycle to school, work or for fun.
Riding a bicycle is a great way to exercise. Ebikes are bringing many older adults back to cycling.
Cities need to do more to encourage people to ride bicycles. Safe protected bike lanes and trails are needed so adults and children can ride safely. Speak up for bicycles in your community. Bicycles make life and cities better. Ask your local transportation planner and elected officials to support more protected bike lanes and trails. Children should be riding a bicycle to school and not be driven in a minivan. Be healthier and happier. Ride a bicycle regularly.
Make a bicycle your transportation option for short distance travel.
Well both my parents got dementia, father vascular, mother Alzheimer's. On my fathers side there was no dementia (both grandparents didn't get it). Not certain about my mother's because both her parents died young. In terms of NEURO and the O, my mother remained very active mentally until her mid 80's working in charities and was a stickler for crossword puzzles and Sudoku. She did them religiously. Both parents did a lot of exercise through walking and lots of physically demanding gardening. Both parents didn't drink heavily and neither ever smoked. The only one on your list that they might have been guilty of was consuming too much sugar, with both eating chocolate - and that being dark, which some reckon is a good form of chocolate. So clearly something else caused their dementia. It's these other factors I think which hold more of a clue to what is really going on. I did some water sampling at their house but it came back supposedly within a normal range. I think there are yet unknown reasons for the causes of dementia beyond just the NEURO formula described in this video.
A question for the excellent Doctors, if they are still able to comment. Would golf, taken seriously, which is a mental as well as a physical challenge combined, qualify as an excellent hedge against Dementia? I might argue that the social aspects of the game can also reduce stress. I can't find any studies of this online.
Very disappointed by generalization of LDL. No discussion of large and small particle LDL.
Agreed. This bit was over simplified
Ive read there are studies from Dr Richard Davidson's research that meditation can improve brain health and even grow some brain regions. Do you feel this is true?
Absolutely 💯 agree.
In terms of reducing stress, certainly, and it may also stimulate the production of certain hormones, but I wouldn't dare to claim it as any affect on growth.
55:50 "...7 to 8 hours of it, of deep sleep..."
What exactly is the definition of "deep"?
According to my Fitbit sleep tracker, on a good night I get one hour of deep sleep, which according to them, this is about average for my age (73).
I hope that's not as bad as it sounds...
My question also. Can't imagine someone having 7-8 hours of deep sleep a night.
Question: flax and chia seeds tend to go though the body undigested so how good source of omega are they really? How about cold pressed hemp oil, or hulled hemp seeds don't they have high omega 3 content with higher bioavailability?
Also, how good or bad is the body at converting ALA to DHA or EPA I wonder.
Too many commercials
I have been resisting taking statins recommended by my gp as my cholesterol is high despite a good diet. After watching this video, I’m beginning to think I should be taking them because of my LDL levels. What do others think?
I am in a similar dilemma 😮 Statins have a myriad of side effects.
Perhaps measure ApoB which is a more relevant overall metric and includes effects from LDL-C. Check out Simon Hill's interviews with the geeks of cholesterol and CVD. Good luck.
Up to you but I would do my own research. Read what Dr Malcolm Kendrick has to say on the matter. He and Zoe Harcombe (no relation to this Zoe) just won their legal case against the Daily Mail who had accused them of being statin deniers and being responsible for people dying as a result of stopping taking them. They were totally vindicated.
Don’t!
I had a babysitter, a nurse, who was physically very active and lean, but even vegetarian diet and benecol dis not lower her very high cholesterol. Only when she went on a vegan diet her cholesterol levels started dropping! I'm not saying it works for everyone but if you are worried about statins you might be motivated enough to try it. Be aware of processed foods such as meat alternatives and ready-made meals though. These days it's all too easy to be vegetarian l/vegan and still have unhealthy diet. Notice also that meat alternatives mostly do not have equivalent amounts of protein. For example, a vegeburger may only have a quarter of the amount of protein than a hamburger or none at all!
That explains Fred Housego
Great I have knee injury can’t do lunges or squats
So, is it too late for me at 65?
What happens to those of us unable to sleep well? 😥
Insomnia! At least try to stay calm and rested and try meditation 🧘♀️ 😌
Deep sleep is a necessity
Please can you get Chris Van Tulleken on one of your forthcoming podcasts 🙏 he is the godfather of ultra processed foods and how bad they are for you!
Oh goodness. For those of you not in the States, this is a Seventh Day Adventist couple from Loma Linda California that push a Vegan diet and STILL try to demonize saturated fatty acids for brain health for religious reasons (the opposite of what actual metabolic doctors like Dr. Georgia Ede and Chris Palmer are researching). They push a very high carbohydrate diet, even though the most up to date research is showing that Alzheimer’s is a disease of hyperinsulinemia and glucose intolerance. It's being referred to as type 3 diabetes for a reason. In their own words:
"Meat and dairy contain high levels of saturated fat which raises blood pressure which isn't just bad for the heart but clogs up the brain too."
They literally still follow the disproven 'belief' that saturated fat, which is metablized into efficient ketone bodies that can cross the blood brain barrier without insulin, somehow 'clogs' our hearts and brains. Ketones do not 'clog' anything.
Be careful or there 🫡.
Loma Linda is considered a “blue zone”. There are lots of experts who recommend a vegan or vegetarian diet.
@redhen689 Oh _goodness._ Don't get me started on the Dan Buettner Blue Zone data. Some other time.
Thank you for that clarification. I was thinking that the negative emphasis they put on saturated fats and dairy clashed with my experience, knowledge and understanding of a ketogenic or low carb diet. It was at this point in the podcast that i started to feel uncomfortable regarding their dietary messages.
@@Caladcholg You do you! I’ll do me. I believe in eating a mostly plant based diet. Zoe has plenty of guests on their program that recommend this style of eating.
@redhen689 sounds like a plan! Just keep an open mind if you start to feel unwell, but, by all means, do what you feel is best/makes you happiest.
Immigrating to another country cured my stress once and for all
thank you. it seems like you need to be your own doctor these days. for everyone reading this i recommend the book the hidden herbs by anette ray
The Interview about seed oils by Sarah Berry on Diary of a CEO was disappointing.
There was a lack of candid openness regarding potential conflict of interest.
Please don't let that happen again as it could undo some of the good work you have done to date.
Trusting the Messenger is of vital importance.
Revering CEOs is a mistake.
It was a car crash. I imagine the Zoe image managers are furious as they couldn’t control the message. Well worth a listen though to hear her call people “cholesterol deniers” as well as laugh at the idea that ultra processed seeds oils might not be a healthy foodstuff.
Might this be more of the great cholesterol con? 🤔
"R" is for regenerative sleep. Lol just embrace the S's
Did she say seven to eight hours of deep sleep? Seems impossible. Or did she misspeak?
Restorative sleep which goes through multiple cycles of which deep is one, rem ia another, etc
@@daveuk1324That's not what I asked. Read 55:44 of the transcript.
NEURO
N Nutrition
E Exercise
U Unwind
R Restorative Sleep
O Optimize
Liver also has ability to grow
I forgot what she was talking about
Why go to the gym when you get the same by cycling or walking where you have to go. Less car more leg muscle!
jonathan,,,, please mate, its not all about you,
Why do these videos have to be so long? We all know why. You could shorten the video content and we could receive the same output. - It's a shame because the overall message is good but you lose a lot of viewers
Dr. Sherzai needs to reduce his weight
The host needs to curtail his own words and diatribe.
For everyone reading this, finding the banned book called “the hidden herbs” by anette ray should be your top priority
Everyone watching this go find the book the hidden herbs by anette ray
I have read many books, I listened to many UA-cam videos by many of the world's leading gurus and health experts but nothing came close to the hidden herbs by anette ray. I recommend everyone giving it a read.
I pray to God that everyone who is reading this gets better and stays healthy. What helped me is using the herbs from the book the hidden herbs by anette ray
I normally don't comment but for everyone reading this go read the hidden herbs by anette ray
Fantastically informative podcast and very easy to listen to. Thank you 😊