CRISPR Explained: Gene Editing History, Technology, and Applications

Discover #CRISPR applications and gene editing history, the mechanism of CRISPR-Cas9, and modeling Cas9 function. Click "Show More" for chapters and free resources 👇
00:00 - Introduction
00:41 - CRISPR applications, history, ethics, and activities
15:40 - How does CRISPR-Cas9 work?
17:38 - Modeling Cas9 molecular mechanism and mathematical specificity
The 2020 Nobel Prize in Chemistry was awarded for CRISPR. Learn more about the Out of the Blue CRISPR Kit and Genotyping Extension, and download free modeling and bioinformatics activities in the instructor and student guides, at bio-rad.com/outoftheblue
Free CRISPR teaching resources at bio-rad.com/teachcrispr
*Correction: the last passenger pigeon died in someone's hands at the Cincinnati Zoo, not the Cleveland Zoo.
See more curated videos on our CRISPR Gene Editing playlist at • CRISPR Gene Editing
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[@davidrosen5137]

I attended the webinar last night. It was extremely helpful! Thanks for putting it on! One question I had is the relationship between CRISPR and restriction enzymes with regards to the natural function of both. Do bacteria have both? One or the other? Can you clarify?

[@BioRadEducation]

Thanks, David! Yes, many bacteria will have CRISPR and traditional restriction enzymes, the former being an adaptive immunity and the latter being an innate immunity against infectious bacteriophage DNA being injected into the cells.

[@mirzamudassir3937]

Nice

[@catescsc]

Great video. Two notes: 1) the tone used during the discussion of eugenics is a bit too gleeful, and 2) the last passenger pigeon died at the Cincinnati zoo, not the Cleveland zoo.

[@BioRadEducation]

Thanks for the correction, catescsc, about the Cincinnati Zoo!